Incidental Mutation 'R0632:Dscaml1'
| ID |
59720 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dscaml1
|
| Ensembl Gene |
ENSMUSG00000032087 |
| Gene Name |
DS cell adhesion molecule like 1 |
| Synonyms |
4921507G06Rik, 4930435C18Rik |
| MMRRC Submission |
038821-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.674)
|
| Stock # |
R0632 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
9 |
| Chromosomal Location |
45426628-45753712 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 45732134 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Phenylalanine
at position 1284
(I1284F)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000034592
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000034592]
|
| AlphaFold |
Q4VA61 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000034592
AA Change: I1284F
PolyPhen 2
Score 0.058 (Sensitivity: 0.94; Specificity: 0.84)
|
| SMART Domains |
Protein: ENSMUSP00000034592
Gene: ENSMUSG00000032087
AA Change: I1284F
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
17 |
N/A |
INTRINSIC |
|
low complexity region
|
28 |
55 |
N/A |
INTRINSIC |
|
IG_like
|
96 |
168 |
1.22e0 |
SMART |
|
IG
|
189 |
277 |
1.15e-3 |
SMART |
|
IGc2
|
296 |
359 |
2.54e-14 |
SMART |
|
IGc2
|
385 |
451 |
8.12e-13 |
SMART |
|
IGc2
|
478 |
550 |
9.55e-10 |
SMART |
|
IGc2
|
575 |
640 |
9.78e-7 |
SMART |
|
IGc2
|
666 |
734 |
5.93e-6 |
SMART |
|
IGc2
|
760 |
832 |
6.75e-10 |
SMART |
|
IG
|
853 |
943 |
1e-3 |
SMART |
|
FN3
|
945 |
1029 |
6.64e-7 |
SMART |
|
FN3
|
1045 |
1133 |
9.46e-12 |
SMART |
|
FN3
|
1148 |
1234 |
3.2e-9 |
SMART |
|
FN3
|
1249 |
1332 |
3.48e-10 |
SMART |
|
IGc2
|
1363 |
1428 |
1.49e-11 |
SMART |
|
FN3
|
1442 |
1522 |
3.42e-9 |
SMART |
|
FN3
|
1537 |
1618 |
2.14e-1 |
SMART |
|
low complexity region
|
1671 |
1683 |
N/A |
INTRINSIC |
|
low complexity region
|
2018 |
2026 |
N/A |
INTRINSIC |
|
low complexity region
|
2035 |
2069 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000216685
|
| Meta Mutation Damage Score |
0.1820 |
| Coding Region Coverage |
- 1x: 99.4%
- 3x: 99.0%
- 10x: 97.8%
- 20x: 96.0%
|
| Validation Efficiency |
95% (81/85) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a member of the Ig superfamily of cell adhesion molecules and is involved in neuronal differentiation. The encoded membrane-bound protein localizes to the cell surface, where it forms aggregates that repel neuronal processes of the same cell type. [provided by RefSeq, Sep 2016]
PHENOTYPE: Mice homozygous for a gene trapped allele exhibit impaired self-avoidance in multiple cell types in the retina. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(4) : Gene trapped(4) |
| Other mutations in this stock |
Total: 80 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acaa1a |
T |
A |
9: 119,347,818 (GRCm38) |
|
probably benign |
Het |
| Adgrg7 |
T |
A |
16: 56,742,589 (GRCm38) |
T462S |
possibly damaging |
Het |
| Akap6 |
A |
T |
12: 52,937,148 (GRCm38) |
N825I |
probably damaging |
Het |
| Ankib1 |
T |
A |
5: 3,772,529 (GRCm38) |
N59I |
probably benign |
Het |
| Anks6 |
T |
C |
4: 47,033,167 (GRCm38) |
S633G |
possibly damaging |
Het |
| Ap4e1 |
C |
A |
2: 127,049,280 (GRCm38) |
Y522* |
probably null |
Het |
| Art5 |
G |
A |
7: 102,097,957 (GRCm38) |
T205I |
probably damaging |
Het |
| Ascc2 |
T |
A |
11: 4,649,855 (GRCm38) |
L176H |
probably damaging |
Het |
| Atp13a5 |
T |
C |
16: 29,298,208 (GRCm38) |
D529G |
probably benign |
Het |
| C2cd4a |
T |
C |
9: 67,831,563 (GRCm38) |
E66G |
probably benign |
Het |
| C8a |
T |
C |
4: 104,856,492 (GRCm38) |
D147G |
probably damaging |
Het |
| Ccdc14 |
T |
C |
16: 34,721,649 (GRCm38) |
V532A |
possibly damaging |
Het |
| Ccdc88a |
T |
A |
11: 29,482,749 (GRCm38) |
|
probably benign |
Het |
| Cfap54 |
C |
T |
10: 92,885,096 (GRCm38) |
E2543K |
unknown |
Het |
| Cldn13 |
C |
T |
5: 134,914,747 (GRCm38) |
E195K |
probably benign |
Het |
| Cp |
A |
G |
3: 19,971,082 (GRCm38) |
S402G |
probably null |
Het |
| Cpa3 |
T |
C |
3: 20,225,194 (GRCm38) |
T194A |
probably benign |
Het |
| Crygf |
C |
A |
1: 65,927,997 (GRCm38) |
Y93* |
probably null |
Het |
| Ctsh |
A |
G |
9: 90,061,582 (GRCm38) |
R87G |
possibly damaging |
Het |
| Cyp2t4 |
A |
G |
7: 27,158,246 (GRCm38) |
D428G |
possibly damaging |
Het |
| Dnah17 |
C |
G |
11: 118,067,682 (GRCm38) |
|
probably benign |
Het |
| Dnah3 |
A |
G |
7: 119,967,905 (GRCm38) |
V2366A |
probably benign |
Het |
| Dsg1c |
T |
C |
18: 20,272,346 (GRCm38) |
|
probably benign |
Het |
| Dst |
G |
T |
1: 34,271,413 (GRCm38) |
R4098L |
probably damaging |
Het |
| Efhb |
A |
G |
17: 53,413,459 (GRCm38) |
|
probably benign |
Het |
| Epha7 |
A |
T |
4: 28,821,104 (GRCm38) |
I90F |
probably damaging |
Het |
| Fam171a2 |
T |
A |
11: 102,437,881 (GRCm38) |
D684V |
probably damaging |
Het |
| Fan1 |
A |
G |
7: 64,363,199 (GRCm38) |
V665A |
possibly damaging |
Het |
| Fbn2 |
A |
G |
18: 58,037,747 (GRCm38) |
C2191R |
probably damaging |
Het |
| Fkbp3 |
G |
A |
12: 65,073,918 (GRCm38) |
A2V |
probably benign |
Het |
| G6pd2 |
A |
G |
5: 61,810,171 (GRCm38) |
N430D |
probably benign |
Het |
| Gm13547 |
T |
A |
2: 29,761,584 (GRCm38) |
D7E |
possibly damaging |
Het |
| H4c9 |
G |
T |
13: 22,041,027 (GRCm38) |
Y99* |
probably null |
Het |
| Hdac5 |
A |
T |
11: 102,205,812 (GRCm38) |
D260E |
probably damaging |
Het |
| Hsf2bp |
T |
C |
17: 32,013,346 (GRCm38) |
E142G |
probably damaging |
Het |
| Igf1r |
C |
T |
7: 68,165,155 (GRCm38) |
T268I |
probably damaging |
Het |
| Inava |
T |
C |
1: 136,227,618 (GRCm38) |
D83G |
probably benign |
Het |
| Kcne3 |
C |
T |
7: 100,184,439 (GRCm38) |
R88C |
probably damaging |
Het |
| Klk1b9 |
G |
T |
7: 43,979,372 (GRCm38) |
G100V |
possibly damaging |
Het |
| Kmt2d |
G |
A |
15: 98,853,581 (GRCm38) |
|
probably benign |
Het |
| Lama1 |
C |
T |
17: 67,752,368 (GRCm38) |
|
probably benign |
Het |
| Lcp2 |
C |
T |
11: 34,082,426 (GRCm38) |
P335S |
possibly damaging |
Het |
| Lrrk2 |
T |
A |
15: 91,796,028 (GRCm38) |
N2047K |
probably damaging |
Het |
| Mcub |
T |
C |
3: 129,918,726 (GRCm38) |
M167V |
probably benign |
Het |
| Mia2 |
T |
C |
12: 59,136,143 (GRCm38) |
L36P |
probably damaging |
Het |
| Mmp13 |
A |
T |
9: 7,282,077 (GRCm38) |
I460F |
possibly damaging |
Het |
| Mmp13 |
G |
A |
9: 7,274,032 (GRCm38) |
G169R |
probably damaging |
Het |
| Msh4 |
A |
G |
3: 153,896,895 (GRCm38) |
I232T |
probably damaging |
Het |
| Msra |
T |
A |
14: 64,210,532 (GRCm38) |
M145L |
probably benign |
Het |
| Myo7a |
A |
T |
7: 98,112,150 (GRCm38) |
|
probably benign |
Het |
| Nme8 |
A |
T |
13: 19,658,036 (GRCm38) |
N422K |
probably damaging |
Het |
| Nol6 |
A |
T |
4: 41,121,115 (GRCm38) |
F353I |
probably damaging |
Het |
| Nphp3 |
A |
G |
9: 104,018,274 (GRCm38) |
K384E |
probably damaging |
Het |
| Or51h5 |
C |
T |
7: 102,928,604 (GRCm38) |
|
probably null |
Het |
| Or52e15 |
A |
G |
7: 104,996,703 (GRCm38) |
I67T |
probably benign |
Het |
| Or52h7 |
A |
G |
7: 104,564,337 (GRCm38) |
I39V |
probably benign |
Het |
| Phox2b |
T |
G |
5: 67,096,214 (GRCm38) |
|
probably benign |
Het |
| Plec |
A |
T |
15: 76,173,411 (GRCm38) |
S4131T |
probably damaging |
Het |
| Pptc7 |
G |
A |
5: 122,313,591 (GRCm38) |
|
probably benign |
Het |
| Pramel31 |
G |
A |
4: 144,363,782 (GRCm38) |
C464Y |
probably damaging |
Het |
| Prpf40b |
A |
G |
15: 99,316,289 (GRCm38) |
E810G |
probably benign |
Het |
| Ptprc |
C |
T |
1: 138,073,610 (GRCm38) |
V965I |
probably benign |
Het |
| Pum1 |
T |
A |
4: 130,728,104 (GRCm38) |
M180K |
probably benign |
Het |
| Ranbp3 |
T |
C |
17: 56,702,896 (GRCm38) |
|
probably benign |
Het |
| Rasgrf2 |
A |
G |
13: 91,972,274 (GRCm38) |
S787P |
probably benign |
Het |
| Rnf19b |
T |
A |
4: 129,073,551 (GRCm38) |
N294K |
probably damaging |
Het |
| Samd3 |
A |
T |
10: 26,244,495 (GRCm38) |
H156L |
possibly damaging |
Het |
| Serpinb6c |
C |
T |
13: 33,880,031 (GRCm38) |
R347Q |
possibly damaging |
Het |
| Slc36a3 |
A |
G |
11: 55,125,080 (GRCm38) |
I416T |
probably damaging |
Het |
| Slc4a4 |
T |
A |
5: 89,129,641 (GRCm38) |
F279Y |
probably damaging |
Het |
| Slc6a2 |
T |
A |
8: 92,992,801 (GRCm38) |
|
probably benign |
Het |
| Snrnp40 |
C |
G |
4: 130,378,043 (GRCm38) |
|
probably null |
Het |
| Tab2 |
A |
G |
10: 7,919,801 (GRCm38) |
S232P |
probably benign |
Het |
| Tacc2 |
A |
T |
7: 130,625,595 (GRCm38) |
K1356* |
probably null |
Het |
| Tmem87a |
A |
G |
2: 120,359,542 (GRCm38) |
S544P |
probably damaging |
Het |
| Trim52 |
T |
A |
14: 106,106,967 (GRCm38) |
C20S |
probably damaging |
Het |
| Usp38 |
A |
T |
8: 81,014,150 (GRCm38) |
V96E |
probably benign |
Het |
| Vmn2r59 |
T |
C |
7: 42,058,884 (GRCm38) |
Y33C |
probably damaging |
Het |
| Vsig10l |
T |
G |
7: 43,464,137 (GRCm38) |
V171G |
probably damaging |
Het |
| Zfp957 |
T |
A |
14: 79,212,920 (GRCm38) |
I480F |
probably damaging |
Het |
|
| Other mutations in Dscaml1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00418:Dscaml1
|
APN |
9 |
45,670,200 (GRCm38) |
nonsense |
probably null |
|
|
IGL00497:Dscaml1
|
APN |
9 |
45,752,238 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL00895:Dscaml1
|
APN |
9 |
45,751,253 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL01011:Dscaml1
|
APN |
9 |
45,683,672 (GRCm38) |
missense |
possibly damaging |
0.76 |
|
IGL01086:Dscaml1
|
APN |
9 |
45,702,662 (GRCm38) |
splice site |
probably benign |
|
|
IGL01125:Dscaml1
|
APN |
9 |
45,749,632 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
IGL01132:Dscaml1
|
APN |
9 |
45,752,328 (GRCm38) |
nonsense |
probably null |
|
|
IGL01356:Dscaml1
|
APN |
9 |
45,746,857 (GRCm38) |
missense |
probably benign |
0.03 |
|
IGL01459:Dscaml1
|
APN |
9 |
45,742,683 (GRCm38) |
nonsense |
probably null |
|
|
IGL01552:Dscaml1
|
APN |
9 |
45,447,908 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02033:Dscaml1
|
APN |
9 |
45,683,782 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02044:Dscaml1
|
APN |
9 |
45,746,943 (GRCm38) |
nonsense |
probably null |
|
|
IGL02095:Dscaml1
|
APN |
9 |
45,447,703 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02166:Dscaml1
|
APN |
9 |
45,683,701 (GRCm38) |
missense |
probably damaging |
0.98 |
|
IGL02262:Dscaml1
|
APN |
9 |
45,732,080 (GRCm38) |
missense |
probably benign |
0.44 |
|
IGL02262:Dscaml1
|
APN |
9 |
45,745,116 (GRCm38) |
missense |
probably benign |
|
|
IGL02340:Dscaml1
|
APN |
9 |
45,670,176 (GRCm38) |
missense |
possibly damaging |
0.66 |
|
IGL02604:Dscaml1
|
APN |
9 |
45,744,328 (GRCm38) |
unclassified |
probably benign |
|
|
IGL02619:Dscaml1
|
APN |
9 |
45,447,796 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02805:Dscaml1
|
APN |
9 |
45,447,897 (GRCm38) |
missense |
probably damaging |
0.98 |
|
IGL03409:Dscaml1
|
APN |
9 |
45,670,103 (GRCm38) |
missense |
probably damaging |
1.00 |
|
D3080:Dscaml1
|
UTSW |
9 |
45,684,325 (GRCm38) |
missense |
probably benign |
0.44 |
|
IGL03050:Dscaml1
|
UTSW |
9 |
45,742,999 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0149:Dscaml1
|
UTSW |
9 |
45,742,680 (GRCm38) |
nonsense |
probably null |
|
|
R0582:Dscaml1
|
UTSW |
9 |
45,668,264 (GRCm38) |
missense |
possibly damaging |
0.77 |
|
R0629:Dscaml1
|
UTSW |
9 |
45,721,418 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R0815:Dscaml1
|
UTSW |
9 |
45,745,074 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1162:Dscaml1
|
UTSW |
9 |
45,752,349 (GRCm38) |
splice site |
probably benign |
|
|
R1449:Dscaml1
|
UTSW |
9 |
45,742,223 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R1474:Dscaml1
|
UTSW |
9 |
45,685,221 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1481:Dscaml1
|
UTSW |
9 |
45,672,643 (GRCm38) |
missense |
probably benign |
0.01 |
|
R1533:Dscaml1
|
UTSW |
9 |
45,450,584 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1542:Dscaml1
|
UTSW |
9 |
45,749,440 (GRCm38) |
missense |
possibly damaging |
0.84 |
|
R1572:Dscaml1
|
UTSW |
9 |
45,721,333 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1627:Dscaml1
|
UTSW |
9 |
45,753,147 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1634:Dscaml1
|
UTSW |
9 |
45,672,749 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1713:Dscaml1
|
UTSW |
9 |
45,752,690 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
R1777:Dscaml1
|
UTSW |
9 |
45,683,756 (GRCm38) |
missense |
possibly damaging |
0.58 |
|
R1812:Dscaml1
|
UTSW |
9 |
45,751,286 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1834:Dscaml1
|
UTSW |
9 |
45,683,632 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1907:Dscaml1
|
UTSW |
9 |
45,740,480 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1953:Dscaml1
|
UTSW |
9 |
45,670,224 (GRCm38) |
missense |
probably benign |
0.01 |
|
R2056:Dscaml1
|
UTSW |
9 |
45,750,132 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R2193:Dscaml1
|
UTSW |
9 |
45,685,234 (GRCm38) |
missense |
probably benign |
0.21 |
|
R2497:Dscaml1
|
UTSW |
9 |
45,745,078 (GRCm38) |
missense |
probably benign |
0.00 |
|
R3768:Dscaml1
|
UTSW |
9 |
45,732,137 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R3891:Dscaml1
|
UTSW |
9 |
45,717,484 (GRCm38) |
missense |
possibly damaging |
0.84 |
|
R4110:Dscaml1
|
UTSW |
9 |
45,732,068 (GRCm38) |
missense |
probably benign |
0.07 |
|
R4706:Dscaml1
|
UTSW |
9 |
45,450,580 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4716:Dscaml1
|
UTSW |
9 |
45,450,592 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4719:Dscaml1
|
UTSW |
9 |
45,672,695 (GRCm38) |
missense |
probably benign |
0.13 |
|
R4770:Dscaml1
|
UTSW |
9 |
45,670,106 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4924:Dscaml1
|
UTSW |
9 |
45,745,189 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5167:Dscaml1
|
UTSW |
9 |
45,717,432 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5346:Dscaml1
|
UTSW |
9 |
45,450,559 (GRCm38) |
missense |
possibly damaging |
0.63 |
|
R5737:Dscaml1
|
UTSW |
9 |
45,745,185 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R5977:Dscaml1
|
UTSW |
9 |
45,721,298 (GRCm38) |
missense |
probably benign |
0.19 |
|
R6073:Dscaml1
|
UTSW |
9 |
45,450,583 (GRCm38) |
missense |
probably benign |
0.22 |
|
R6276:Dscaml1
|
UTSW |
9 |
45,668,160 (GRCm38) |
missense |
possibly damaging |
0.62 |
|
R6415:Dscaml1
|
UTSW |
9 |
45,683,677 (GRCm38) |
nonsense |
probably null |
|
|
R6527:Dscaml1
|
UTSW |
9 |
45,712,184 (GRCm38) |
nonsense |
probably null |
|
|
R6582:Dscaml1
|
UTSW |
9 |
45,752,806 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6655:Dscaml1
|
UTSW |
9 |
45,746,937 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6772:Dscaml1
|
UTSW |
9 |
45,710,311 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6799:Dscaml1
|
UTSW |
9 |
45,450,583 (GRCm38) |
missense |
probably benign |
0.22 |
|
R6892:Dscaml1
|
UTSW |
9 |
45,683,830 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R6918:Dscaml1
|
UTSW |
9 |
45,430,507 (GRCm38) |
missense |
probably benign |
|
|
R6967:Dscaml1
|
UTSW |
9 |
45,674,523 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R7214:Dscaml1
|
UTSW |
9 |
45,670,139 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7286:Dscaml1
|
UTSW |
9 |
45,742,746 (GRCm38) |
critical splice donor site |
probably null |
|
|
R7315:Dscaml1
|
UTSW |
9 |
45,745,125 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7338:Dscaml1
|
UTSW |
9 |
45,674,504 (GRCm38) |
missense |
probably benign |
0.12 |
|
R7343:Dscaml1
|
UTSW |
9 |
45,752,916 (GRCm38) |
missense |
probably benign |
|
|
R7395:Dscaml1
|
UTSW |
9 |
45,702,405 (GRCm38) |
missense |
possibly damaging |
0.73 |
|
R7439:Dscaml1
|
UTSW |
9 |
45,710,326 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R7484:Dscaml1
|
UTSW |
9 |
45,749,446 (GRCm38) |
splice site |
probably null |
|
|
R7545:Dscaml1
|
UTSW |
9 |
45,685,383 (GRCm38) |
missense |
probably benign |
0.11 |
|
R7979:Dscaml1
|
UTSW |
9 |
45,683,731 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8005:Dscaml1
|
UTSW |
9 |
45,717,510 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8181:Dscaml1
|
UTSW |
9 |
45,746,842 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
R8262:Dscaml1
|
UTSW |
9 |
45,747,140 (GRCm38) |
intron |
probably benign |
|
|
R8428:Dscaml1
|
UTSW |
9 |
45,742,586 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8725:Dscaml1
|
UTSW |
9 |
45,430,461 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8727:Dscaml1
|
UTSW |
9 |
45,430,461 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8796:Dscaml1
|
UTSW |
9 |
45,447,728 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R8840:Dscaml1
|
UTSW |
9 |
45,723,420 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R9291:Dscaml1
|
UTSW |
9 |
45,447,953 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9394:Dscaml1
|
UTSW |
9 |
45,750,056 (GRCm38) |
missense |
possibly damaging |
0.64 |
|
R9610:Dscaml1
|
UTSW |
9 |
45,668,224 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R9611:Dscaml1
|
UTSW |
9 |
45,668,224 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R9653:Dscaml1
|
UTSW |
9 |
45,732,168 (GRCm38) |
critical splice donor site |
probably null |
|
|
R9699:Dscaml1
|
UTSW |
9 |
45,743,017 (GRCm38) |
missense |
probably damaging |
0.97 |
|
X0058:Dscaml1
|
UTSW |
9 |
45,752,128 (GRCm38) |
missense |
probably benign |
0.00 |
|
Z1177:Dscaml1
|
UTSW |
9 |
45,672,791 (GRCm38) |
missense |
probably damaging |
0.98 |
|
| Predicted Primers |
PCR Primer
(F):5'- CCTGACCAAACACTTGTGAAGCTGG -3'
(R):5'- GGCCCATGATGGATGATAGCACAC -3'
Sequencing Primer
(F):5'- CTGTAGGCCATGCTCAGC -3'
(R):5'- gcttagtctcaggtcctcg -3'
|
| Posted On |
2013-07-11 |
Incidental Mutation