Incidental Mutation 'R7763:Abca16'
| ID |
598030 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Abca16
|
| Ensembl Gene |
ENSMUSG00000051900 |
| Gene Name |
ATP-binding cassette, sub-family A member 16 |
| Synonyms |
|
| MMRRC Submission |
045819-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7763 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
7 |
| Chromosomal Location |
120008870-120144036 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 120113825 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Tryptophan to Arginine
at position 899
(W899R)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000112736
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000056042]
[ENSMUST00000120490]
|
| AlphaFold |
E9PWJ7 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000056042
AA Change: W898R
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000061094
Gene: ENSMUSG00000051900
AA Change: W898R
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:ABC2_membrane_3
|
26 |
455 |
2.7e-23 |
PFAM |
|
AAA
|
537 |
720 |
2.01e-7 |
SMART |
|
Pfam:ABC2_membrane_3
|
898 |
1287 |
4.6e-25 |
PFAM |
|
low complexity region
|
1325 |
1336 |
N/A |
INTRINSIC |
|
low complexity region
|
1342 |
1353 |
N/A |
INTRINSIC |
|
AAA
|
1378 |
1563 |
4.23e-6 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000120490
AA Change: W899R
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000112736
Gene: ENSMUSG00000051900
AA Change: W899R
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:ABC2_membrane_3
|
25 |
456 |
2.4e-22 |
PFAM |
|
AAA
|
538 |
721 |
2.01e-7 |
SMART |
|
Pfam:ABC2_membrane_3
|
899 |
1288 |
1.1e-27 |
PFAM |
|
low complexity region
|
1326 |
1337 |
N/A |
INTRINSIC |
|
low complexity region
|
1343 |
1354 |
N/A |
INTRINSIC |
|
AAA
|
1379 |
1564 |
4.23e-6 |
SMART |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.0%
|
| Validation Efficiency |
|
| Allele List at MGI |
All alleles(4) : Targeted(3) Gene trapped(1)
|
| Other mutations in this stock |
Total: 111 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca5 |
A |
T |
11: 110,163,323 (GRCm39) |
W1631R |
possibly damaging |
Het |
| Actg2 |
T |
A |
6: 83,504,350 (GRCm39) |
D25V |
probably damaging |
Het |
| Akap10 |
G |
C |
11: 61,806,331 (GRCm39) |
D132E |
probably damaging |
Het |
| Angptl2 |
G |
T |
2: 33,132,394 (GRCm39) |
E334* |
probably null |
Het |
| Aprt |
T |
C |
8: 123,301,674 (GRCm39) |
R165G |
probably benign |
Het |
| Bmp1 |
A |
G |
14: 70,729,524 (GRCm39) |
F549S |
probably damaging |
Het |
| Capzb |
C |
T |
4: 139,007,864 (GRCm39) |
T215I |
probably benign |
Het |
| Car14 |
C |
T |
3: 95,811,684 (GRCm39) |
M1I |
probably null |
Het |
| Ccdc148 |
T |
A |
2: 58,713,648 (GRCm39) |
Q501L |
probably benign |
Het |
| Ccdc32 |
G |
A |
2: 118,857,828 (GRCm39) |
T12I |
probably damaging |
Het |
| Ccnf |
G |
A |
17: 24,443,986 (GRCm39) |
S594L |
probably damaging |
Het |
| Cdadc1 |
C |
T |
14: 59,811,283 (GRCm39) |
C409Y |
probably damaging |
Het |
| Cdh23 |
G |
T |
10: 60,148,356 (GRCm39) |
S2670R |
probably damaging |
Het |
| Cdh8 |
T |
A |
8: 100,006,306 (GRCm39) |
K94* |
probably null |
Het |
| Cdhr2 |
A |
T |
13: 54,865,505 (GRCm39) |
Y193F |
probably damaging |
Het |
| Cdon |
T |
A |
9: 35,365,711 (GRCm39) |
Y153* |
probably null |
Het |
| Chd1 |
G |
A |
17: 15,953,303 (GRCm39) |
G413R |
probably damaging |
Het |
| Cit |
A |
T |
5: 116,125,060 (GRCm39) |
T1582S |
probably benign |
Het |
| Clec4a3 |
T |
C |
6: 122,941,299 (GRCm39) |
L98P |
probably benign |
Het |
| Cpa4 |
T |
A |
6: 30,583,644 (GRCm39) |
D253E |
probably damaging |
Het |
| Cyp2c40 |
T |
A |
19: 39,795,612 (GRCm39) |
N189I |
possibly damaging |
Het |
| Daam2 |
G |
T |
17: 49,797,050 (GRCm39) |
A245E |
probably benign |
Het |
| Dennd5b |
A |
G |
6: 148,970,156 (GRCm39) |
F121S |
probably damaging |
Het |
| Dgkd |
A |
G |
1: 87,854,671 (GRCm39) |
T658A |
probably benign |
Het |
| Dmwd |
T |
A |
7: 18,814,265 (GRCm39) |
L305Q |
probably damaging |
Het |
| Dnah5 |
A |
T |
15: 28,314,001 (GRCm39) |
Y1939F |
probably damaging |
Het |
| Dock5 |
T |
C |
14: 68,058,776 (GRCm39) |
T512A |
probably damaging |
Het |
| Dop1b |
T |
A |
16: 93,552,402 (GRCm39) |
D398E |
probably benign |
Het |
| Eef1akmt4 |
A |
G |
16: 20,437,279 (GRCm39) |
H207R |
probably damaging |
Het |
| Egfr |
T |
C |
11: 16,841,266 (GRCm39) |
V719A |
probably damaging |
Het |
| Ep300 |
A |
T |
15: 81,470,784 (GRCm39) |
|
probably benign |
Het |
| Epha4 |
A |
G |
1: 77,366,668 (GRCm39) |
|
probably null |
Het |
| Erc2 |
T |
G |
14: 27,598,161 (GRCm39) |
|
probably null |
Het |
| Ergic1 |
A |
T |
17: 26,857,801 (GRCm39) |
Y209F |
possibly damaging |
Het |
| Fbxw28 |
A |
G |
9: 109,155,701 (GRCm39) |
I357T |
probably damaging |
Het |
| Flnb |
A |
T |
14: 7,926,478 (GRCm38) |
T1841S |
probably benign |
Het |
| Foxc1 |
G |
A |
13: 31,992,011 (GRCm39) |
S274N |
probably benign |
Het |
| Fto |
C |
T |
8: 92,136,071 (GRCm39) |
T115M |
probably damaging |
Het |
| Gm10228 |
C |
G |
16: 88,838,187 (GRCm39) |
C39S |
unknown |
Het |
| Gm7334 |
T |
C |
17: 51,005,743 (GRCm39) |
F10L |
possibly damaging |
Het |
| Hfm1 |
A |
G |
5: 107,029,727 (GRCm39) |
Y785H |
probably damaging |
Het |
| Hivep1 |
T |
A |
13: 42,312,937 (GRCm39) |
S1726T |
probably benign |
Het |
| Htt |
G |
T |
5: 35,009,534 (GRCm39) |
C1505F |
probably damaging |
Het |
| Hydin |
T |
C |
8: 111,232,475 (GRCm39) |
S1665P |
possibly damaging |
Het |
| Ifi209 |
T |
A |
1: 173,470,445 (GRCm39) |
N344K |
probably damaging |
Het |
| Ifnar2 |
T |
C |
16: 91,196,181 (GRCm39) |
M262T |
probably benign |
Het |
| Ighv7-3 |
T |
A |
12: 114,116,827 (GRCm39) |
S112C |
probably damaging |
Het |
| Igkv4-86 |
A |
G |
6: 68,887,563 (GRCm39) |
S59P |
probably benign |
Het |
| Iglv1 |
A |
G |
16: 18,904,239 (GRCm39) |
|
probably benign |
Het |
| Ipo7 |
T |
A |
7: 109,652,006 (GRCm39) |
D928E |
possibly damaging |
Het |
| Itgae |
G |
T |
11: 73,014,095 (GRCm39) |
|
probably null |
Het |
| Kbtbd12 |
T |
A |
6: 88,595,179 (GRCm39) |
Q217L |
probably benign |
Het |
| Kcnma1 |
T |
A |
14: 23,350,074 (GRCm39) |
Y1155F |
possibly damaging |
Het |
| Kif14 |
A |
G |
1: 136,444,121 (GRCm39) |
E1371G |
probably benign |
Het |
| Lilrb4a |
A |
T |
10: 51,367,142 (GRCm39) |
Y10F |
probably benign |
Het |
| Lrp2 |
A |
T |
2: 69,333,732 (GRCm39) |
V1503E |
probably damaging |
Het |
| Mfsd6 |
A |
T |
1: 52,747,799 (GRCm39) |
D355E |
probably benign |
Het |
| Mri1 |
T |
C |
8: 84,977,657 (GRCm39) |
H226R |
|
Het |
| Mroh4 |
C |
T |
15: 74,496,554 (GRCm39) |
E278K |
probably damaging |
Het |
| Muc4 |
T |
A |
16: 32,574,739 (GRCm39) |
L1063H |
probably benign |
Het |
| Mzf1 |
A |
T |
7: 12,778,018 (GRCm39) |
I541N |
probably damaging |
Het |
| Nasp |
T |
A |
4: 116,469,230 (GRCm39) |
E116D |
probably benign |
Het |
| Nlrp10 |
T |
A |
7: 108,525,033 (GRCm39) |
E149V |
probably damaging |
Het |
| Notch4 |
G |
A |
17: 34,801,392 (GRCm39) |
C1080Y |
probably damaging |
Het |
| Nova1 |
T |
G |
12: 46,767,481 (GRCm39) |
I147L |
unknown |
Het |
| Ogdh |
A |
G |
11: 6,288,558 (GRCm39) |
M223V |
probably benign |
Het |
| Or2a56 |
T |
C |
6: 42,932,723 (GRCm39) |
I97T |
probably benign |
Het |
| Or2y1e |
G |
T |
11: 49,218,498 (GRCm39) |
A87S |
probably benign |
Het |
| Or4n4 |
A |
T |
14: 50,518,945 (GRCm39) |
I255N |
probably damaging |
Het |
| Or6c66b |
G |
T |
10: 129,377,324 (GRCm39) |
R306L |
probably benign |
Het |
| P3h3 |
T |
C |
6: 124,831,395 (GRCm39) |
Q330R |
probably benign |
Het |
| Pcdhb10 |
A |
G |
18: 37,544,935 (GRCm39) |
T4A |
not run |
Het |
| Pkd2l2 |
A |
T |
18: 34,566,340 (GRCm39) |
|
probably null |
Het |
| Plekhb1 |
C |
T |
7: 100,294,870 (GRCm39) |
V168I |
probably benign |
Het |
| Plxna4 |
C |
T |
6: 32,200,915 (GRCm39) |
R753H |
probably damaging |
Het |
| Pramel17 |
T |
C |
4: 101,694,338 (GRCm39) |
I182V |
possibly damaging |
Het |
| Prex1 |
G |
C |
2: 166,555,629 (GRCm39) |
P4A |
unknown |
Het |
| Ptgdr |
A |
G |
14: 45,096,535 (GRCm39) |
V59A |
probably damaging |
Het |
| Ralgapa1 |
T |
A |
12: 55,804,740 (GRCm39) |
I519F |
probably benign |
Het |
| Rbpms |
A |
G |
8: 34,279,481 (GRCm39) |
I170T |
probably benign |
Het |
| Sec31b |
T |
A |
19: 44,512,274 (GRCm39) |
|
probably null |
Het |
| Skint11 |
A |
T |
4: 114,084,905 (GRCm39) |
Y138F |
probably benign |
Het |
| Slain2 |
A |
G |
5: 73,105,953 (GRCm39) |
Y196C |
probably damaging |
Het |
| Slco1b2 |
T |
A |
6: 141,621,950 (GRCm39) |
C503* |
probably null |
Het |
| Slfn3 |
A |
T |
11: 83,105,614 (GRCm39) |
Y537F |
possibly damaging |
Het |
| Slu7 |
T |
C |
11: 43,335,592 (GRCm39) |
Y443H |
probably damaging |
Het |
| Sorl1 |
T |
A |
9: 41,955,205 (GRCm39) |
E683D |
probably damaging |
Het |
| Sos1 |
T |
A |
17: 80,721,142 (GRCm39) |
I893L |
probably benign |
Het |
| St8sia2 |
T |
A |
7: 73,593,069 (GRCm39) |
Y329F |
probably damaging |
Het |
| Stra6l |
C |
A |
4: 45,869,570 (GRCm39) |
S212* |
probably null |
Het |
| Syne3 |
C |
T |
12: 104,963,754 (GRCm39) |
|
probably benign |
Het |
| Tenm4 |
T |
A |
7: 96,544,899 (GRCm39) |
I2342N |
probably benign |
Het |
| Tescl |
T |
A |
7: 24,032,688 (GRCm39) |
E212D |
probably benign |
Het |
| Trip11 |
A |
G |
12: 101,811,114 (GRCm39) |
S1879P |
probably benign |
Het |
| Ube2c |
A |
T |
2: 164,613,211 (GRCm39) |
|
probably null |
Het |
| Umodl1 |
T |
A |
17: 31,205,430 (GRCm39) |
I675N |
probably benign |
Het |
| Vipr2 |
T |
C |
12: 116,086,338 (GRCm39) |
F121S |
probably damaging |
Het |
| Vmn1r206 |
A |
T |
13: 22,804,839 (GRCm39) |
S123T |
possibly damaging |
Het |
| Vmn1r58 |
A |
G |
7: 5,413,912 (GRCm39) |
V106A |
probably damaging |
Het |
| Vmn2r112 |
A |
G |
17: 22,822,099 (GRCm39) |
Y259C |
probably damaging |
Het |
| Vmn2r66 |
T |
C |
7: 84,654,909 (GRCm39) |
K467E |
probably benign |
Het |
| Vmn2r98 |
T |
C |
17: 19,300,797 (GRCm39) |
F600L |
probably benign |
Het |
| Vps13a |
T |
A |
19: 16,723,364 (GRCm39) |
N278I |
possibly damaging |
Het |
| Vwa5a |
A |
C |
9: 38,652,458 (GRCm39) |
D747A |
possibly damaging |
Het |
| Xdh |
G |
A |
17: 74,241,829 (GRCm39) |
P157S |
possibly damaging |
Het |
| Xrn1 |
G |
A |
9: 95,880,401 (GRCm39) |
|
probably null |
Het |
| Zfp362 |
T |
A |
4: 128,680,824 (GRCm39) |
H180L |
probably benign |
Het |
| Zfp560 |
A |
T |
9: 20,258,619 (GRCm39) |
W748R |
possibly damaging |
Het |
| Zfp808 |
A |
T |
13: 62,320,478 (GRCm39) |
Q569L |
probably benign |
Het |
| Zfp93 |
T |
A |
7: 23,974,643 (GRCm39) |
D209E |
possibly damaging |
Het |
| Zftraf1 |
A |
T |
15: 76,542,747 (GRCm39) |
Y138N |
probably damaging |
Het |
|
| Other mutations in Abca16 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00417:Abca16
|
APN |
7 |
120,022,982 (GRCm39) |
missense |
probably benign |
0.08 |
|
IGL00590:Abca16
|
APN |
7 |
120,023,038 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01320:Abca16
|
APN |
7 |
120,038,422 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01322:Abca16
|
APN |
7 |
120,038,422 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01613:Abca16
|
APN |
7 |
120,140,500 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL01774:Abca16
|
APN |
7 |
120,021,024 (GRCm39) |
splice site |
probably benign |
|
|
IGL01774:Abca16
|
APN |
7 |
120,077,058 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01797:Abca16
|
APN |
7 |
120,113,760 (GRCm39) |
missense |
probably benign |
0.15 |
|
IGL02406:Abca16
|
APN |
7 |
120,139,825 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02437:Abca16
|
APN |
7 |
120,132,952 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02541:Abca16
|
APN |
7 |
120,113,881 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL02576:Abca16
|
APN |
7 |
120,032,678 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02578:Abca16
|
APN |
7 |
120,023,179 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL03156:Abca16
|
APN |
7 |
120,023,074 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
IGL03381:Abca16
|
APN |
7 |
120,127,041 (GRCm39) |
missense |
probably benign |
0.12 |
|
PIT4802001:Abca16
|
UTSW |
7 |
120,139,351 (GRCm39) |
missense |
probably benign |
0.31 |
|
R0024:Abca16
|
UTSW |
7 |
120,032,608 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0026:Abca16
|
UTSW |
7 |
120,077,146 (GRCm39) |
splice site |
probably benign |
|
|
R0026:Abca16
|
UTSW |
7 |
120,077,146 (GRCm39) |
splice site |
probably benign |
|
|
R0123:Abca16
|
UTSW |
7 |
120,139,378 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0134:Abca16
|
UTSW |
7 |
120,139,378 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0225:Abca16
|
UTSW |
7 |
120,139,378 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0346:Abca16
|
UTSW |
7 |
120,035,155 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0355:Abca16
|
UTSW |
7 |
120,023,021 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R0358:Abca16
|
UTSW |
7 |
120,143,939 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0525:Abca16
|
UTSW |
7 |
120,065,033 (GRCm39) |
nonsense |
probably null |
|
|
R0617:Abca16
|
UTSW |
7 |
120,032,834 (GRCm39) |
splice site |
probably benign |
|
|
R0625:Abca16
|
UTSW |
7 |
120,035,116 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0835:Abca16
|
UTSW |
7 |
120,065,007 (GRCm39) |
missense |
probably benign |
0.42 |
|
R1445:Abca16
|
UTSW |
7 |
120,119,256 (GRCm39) |
missense |
probably benign |
0.41 |
|
R1535:Abca16
|
UTSW |
7 |
120,139,928 (GRCm39) |
missense |
probably benign |
0.30 |
|
R1567:Abca16
|
UTSW |
7 |
120,030,352 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1694:Abca16
|
UTSW |
7 |
120,119,307 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1860:Abca16
|
UTSW |
7 |
120,133,986 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1876:Abca16
|
UTSW |
7 |
120,032,608 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1913:Abca16
|
UTSW |
7 |
120,140,463 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1940:Abca16
|
UTSW |
7 |
120,032,832 (GRCm39) |
splice site |
probably benign |
|
|
R2042:Abca16
|
UTSW |
7 |
120,143,941 (GRCm39) |
missense |
probably benign |
|
|
R2115:Abca16
|
UTSW |
7 |
120,139,868 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2122:Abca16
|
UTSW |
7 |
120,119,184 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2265:Abca16
|
UTSW |
7 |
120,030,383 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2267:Abca16
|
UTSW |
7 |
120,030,383 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2269:Abca16
|
UTSW |
7 |
120,030,383 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2993:Abca16
|
UTSW |
7 |
120,134,384 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3055:Abca16
|
UTSW |
7 |
120,035,074 (GRCm39) |
missense |
probably benign |
0.05 |
|
R3956:Abca16
|
UTSW |
7 |
120,126,975 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4114:Abca16
|
UTSW |
7 |
120,126,290 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4441:Abca16
|
UTSW |
7 |
120,127,024 (GRCm39) |
missense |
probably benign |
0.04 |
|
R4601:Abca16
|
UTSW |
7 |
120,035,920 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4706:Abca16
|
UTSW |
7 |
120,064,988 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4807:Abca16
|
UTSW |
7 |
120,139,832 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4824:Abca16
|
UTSW |
7 |
120,074,702 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R4937:Abca16
|
UTSW |
7 |
120,126,309 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5152:Abca16
|
UTSW |
7 |
120,139,846 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5257:Abca16
|
UTSW |
7 |
120,035,992 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5258:Abca16
|
UTSW |
7 |
120,035,992 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5330:Abca16
|
UTSW |
7 |
120,102,600 (GRCm39) |
missense |
probably benign |
0.15 |
|
R5388:Abca16
|
UTSW |
7 |
120,139,969 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5590:Abca16
|
UTSW |
7 |
120,143,995 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5810:Abca16
|
UTSW |
7 |
120,035,155 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6030:Abca16
|
UTSW |
7 |
120,133,021 (GRCm39) |
missense |
probably benign |
|
|
R6030:Abca16
|
UTSW |
7 |
120,133,021 (GRCm39) |
missense |
probably benign |
|
|
R6161:Abca16
|
UTSW |
7 |
120,139,934 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6313:Abca16
|
UTSW |
7 |
120,126,344 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6485:Abca16
|
UTSW |
7 |
120,026,390 (GRCm39) |
nonsense |
probably null |
|
|
R6527:Abca16
|
UTSW |
7 |
120,076,995 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6772:Abca16
|
UTSW |
7 |
120,126,276 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6885:Abca16
|
UTSW |
7 |
120,119,332 (GRCm39) |
missense |
probably benign |
0.07 |
|
R6899:Abca16
|
UTSW |
7 |
120,126,264 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6941:Abca16
|
UTSW |
7 |
120,140,370 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6990:Abca16
|
UTSW |
7 |
120,126,950 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7059:Abca16
|
UTSW |
7 |
120,020,971 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7144:Abca16
|
UTSW |
7 |
120,032,796 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7146:Abca16
|
UTSW |
7 |
120,126,974 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7193:Abca16
|
UTSW |
7 |
120,026,409 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7308:Abca16
|
UTSW |
7 |
120,022,993 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7449:Abca16
|
UTSW |
7 |
120,035,131 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7571:Abca16
|
UTSW |
7 |
120,119,211 (GRCm39) |
missense |
probably benign |
0.11 |
|
R7617:Abca16
|
UTSW |
7 |
120,102,694 (GRCm39) |
nonsense |
probably null |
|
|
R7646:Abca16
|
UTSW |
7 |
120,113,937 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7750:Abca16
|
UTSW |
7 |
120,113,928 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7840:Abca16
|
UTSW |
7 |
120,074,689 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7946:Abca16
|
UTSW |
7 |
120,126,398 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8018:Abca16
|
UTSW |
7 |
120,132,866 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8170:Abca16
|
UTSW |
7 |
120,065,005 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8413:Abca16
|
UTSW |
7 |
120,023,123 (GRCm39) |
missense |
probably benign |
0.06 |
|
R8461:Abca16
|
UTSW |
7 |
120,035,918 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8858:Abca16
|
UTSW |
7 |
120,052,327 (GRCm39) |
missense |
probably benign |
|
|
R8881:Abca16
|
UTSW |
7 |
120,074,794 (GRCm39) |
missense |
probably benign |
0.18 |
|
R9272:Abca16
|
UTSW |
7 |
120,076,993 (GRCm39) |
missense |
probably benign |
0.13 |
|
R9303:Abca16
|
UTSW |
7 |
120,126,989 (GRCm39) |
missense |
probably benign |
0.25 |
|
R9305:Abca16
|
UTSW |
7 |
120,126,989 (GRCm39) |
missense |
probably benign |
0.25 |
|
R9320:Abca16
|
UTSW |
7 |
120,139,320 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9413:Abca16
|
UTSW |
7 |
120,126,422 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9512:Abca16
|
UTSW |
7 |
120,022,963 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9559:Abca16
|
UTSW |
7 |
120,021,019 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9615:Abca16
|
UTSW |
7 |
120,126,404 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9641:Abca16
|
UTSW |
7 |
120,126,308 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R9643:Abca16
|
UTSW |
7 |
120,065,023 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R9674:Abca16
|
UTSW |
7 |
120,074,668 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R9714:Abca16
|
UTSW |
7 |
120,030,383 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9799:Abca16
|
UTSW |
7 |
120,132,998 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9800:Abca16
|
UTSW |
7 |
120,119,283 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
RF020:Abca16
|
UTSW |
7 |
120,132,880 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
X0066:Abca16
|
UTSW |
7 |
120,102,609 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGACTGTTAGTGAATAGTGGTGTCC -3'
(R):5'- GAGATTCAGAGCCAAATCAGAATTCC -3'
Sequencing Primer
(F):5'- TGAAGAAAACCCTTCAGATCTTTG -3'
(R):5'- GCCAAATCAGAATTCCCTGAAGTTG -3'
|
| Posted On |
2019-11-26 |
Incidental Mutation