Mutagenetix > Incidental Mutation

Incidental Mutation 'R7767:Dnhd1'

598302

Institutional Source

Beutler Lab

Gene Symbol

Dnhd1

Ensembl Gene

ENSMUSG00000030882

Gene Name

dynein heavy chain domain 1

Synonyms

8030491N06Rik

MMRRC Submission

045823-MU

Accession Numbers

Variant 1:ENSMUST00000145988; OTTMUST00000062891; Variant 2: ENSMUST00000106773; Variant 3: ENSMUST00000106776; Variant 4: ENSMUST00000163171; Variant 5: ENSMUST00000142363;OTTMUST00000062869; Variant 6: ENSMUST00000142874; OTTMUST00000062870; Variant 7: ENSMUST00000128388; OTTMUST00000062892; MGI:1924755

Essential gene?

Probably non essential (E-score: 0.077) question?

Stock #

R7767 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

105650827-105721799 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 105694610 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Isoleucine to Methionine at position 1720 (I1720M)

Ref Sequence

ENSEMBL: ENSMUSP00000121261 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000145988]

AlphaFold

no structure available at present

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000118658

Predicted Effect

probably benign
Transcript: ENSMUST00000145988
AA Change: I1720M

PolyPhen 2 Score 0.380 (Sensitivity: 0.90; Specificity: 0.89)

SMART Domains

Protein: ENSMUSP00000121261
Gene: ENSMUSG00000030882
AA Change: I1720M

Domain	Start	End	E-Value	Type
low complexity region	5	18	N/A	INTRINSIC
low complexity region	102	115	N/A	INTRINSIC
low complexity region	183	191	N/A	INTRINSIC
low complexity region	253	269	N/A	INTRINSIC
low complexity region	943	962	N/A	INTRINSIC
Pfam:DHC_N2	1018	1472	4.6e-50	PFAM
Pfam:AAA_6	1652	1875	2.7e-14	PFAM
low complexity region	1906	1918	N/A	INTRINSIC
Blast:AAA	1993	2196	1e-34	BLAST
Pfam:AAA_7	2362	2610	3.3e-11	PFAM
low complexity region	2697	2714	N/A	INTRINSIC
low complexity region	2722	2733	N/A	INTRINSIC
low complexity region	2800	2810	N/A	INTRINSIC
low complexity region	3116	3134	N/A	INTRINSIC
Pfam:MT	3178	3470	3.9e-16	PFAM
coiled coil region	3590	3642	N/A	INTRINSIC
coiled coil region	3816	3843	N/A	INTRINSIC
Pfam:Dynein_heavy	3976	4746	7.3e-97	PFAM

Meta Mutation Damage Score

0.2109

Coding Region Coverage

1x: 100.0%
3x: 100.0%
10x: 99.8%
20x: 99.3%

Validation Efficiency

Allele List at MGI

All alleles(1) : Gene trapped(1)

Other mutations in this stock

Total: 77 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4932438A13Rik	G	T	3: 36,920,287 (GRCm38)		probably null	Het
Aox4	C	A	1: 58,235,207 (GRCm38)	S384Y	probably damaging	Het
Arhgef15	T	C	11: 68,953,847 (GRCm38)	E308G	probably damaging	Het
Asb15	A	G	6: 24,559,282 (GRCm38)	D142G	probably benign	Het
Atg13	A	G	2: 91,679,366 (GRCm38)	S394P	probably damaging	Het
Atp10a	G	C	7: 58,658,849 (GRCm38)	W132S	probably damaging	Het
BC003331	A	G	1: 150,372,037 (GRCm38)	V387A	probably benign	Het
Bod1l	T	A	5: 41,816,756 (GRCm38)	N2405I	probably benign	Het
Capsl	C	T	15: 9,462,684 (GRCm38)	R137C	probably damaging	Het
Cd109	T	A	9: 78,710,159 (GRCm38)	M1313K	probably damaging	Het
Chst13	G	A	6: 90,309,584 (GRCm38)	A132V	possibly damaging	Het
Cobl	T	C	11: 12,412,117 (GRCm38)		probably benign	Het
Coq9	A	T	8: 94,850,586 (GRCm38)	E193V	probably benign	Het
Cpd	T	A	11: 76,813,559 (GRCm38)	I410F	probably benign	Het
Cyth3	T	G	5: 143,707,474 (GRCm38)	V351G	probably damaging	Het
Dcdc2c	T	C	12: 28,470,257 (GRCm38)	K607E		Het
Dcp1a	T	C	14: 30,479,818 (GRCm38)		probably null	Het
Dennd3	A	G	15: 73,522,230 (GRCm38)	I35V	probably benign	Het
Dlgap4	C	T	2: 156,746,053 (GRCm38)	R606W	probably damaging	Het
Erbin	A	G	13: 103,859,399 (GRCm38)	L265P	probably damaging	Het
Ern1	T	C	11: 106,400,308 (GRCm38)	D847G	probably damaging	Het
Esyt3	T	G	9: 99,324,971 (GRCm38)	S342R	probably benign	Het
Exoc2	A	T	13: 30,876,769 (GRCm38)	I584K	probably benign	Het
Fam240a	T	C	9: 110,915,022 (GRCm38)	R50G	probably damaging	Het
Glis3	A	T	19: 28,263,960 (GRCm38)	M858K	probably benign	Het
Gls2	C	T	10: 128,195,129 (GRCm38)	R86C	unknown	Het
Gm10972	C	A	3: 94,643,594 (GRCm38)	Y25*	probably null	Het
H2-T10	A	T	17: 36,117,730 (GRCm38)	M350K	probably benign	Het
Has1	A	T	17: 17,850,530 (GRCm38)	V43D	probably damaging	Het
Herc2	T	A	7: 56,228,527 (GRCm38)	S4609R	probably benign	Het
Hmgcs2	A	C	3: 98,291,266 (GRCm38)	T162P	probably damaging	Het
Hspg2	G	T	4: 137,511,866 (GRCm38)	C368F	probably damaging	Het
Ighv11-1	A	G	12: 113,982,102 (GRCm38)	S44P	probably damaging	Het
Inppl1	A	G	7: 101,824,338 (GRCm38)	V1035A	probably benign	Het
Kmt2a	C	T	9: 44,818,998 (GRCm38)	V3341I	unknown	Het
Lrp1b	T	C	2: 40,801,505 (GRCm38)	N3434S		Het
Lrriq1	G	C	10: 103,215,954 (GRCm38)	S312R	probably damaging	Het
Map1a	G	A	2: 121,302,036 (GRCm38)	S1111N	probably damaging	Het
Myo15	T	C	11: 60,502,096 (GRCm38)	V1029A		Het
Nol11	T	C	11: 107,179,082 (GRCm38)	H314R	possibly damaging	Het
Nphs1	A	T	7: 30,463,308 (GRCm38)	D404V	probably damaging	Het
Olfr550	A	T	7: 102,571,764 (GRCm38)		probably benign	Het
Pabpc2	T	C	18: 39,774,554 (GRCm38)	Y291H	possibly damaging	Het
Pcdh15	G	A	10: 74,486,256 (GRCm38)	A1020T	probably benign	Het
Pla2g4f	A	C	2: 120,305,009 (GRCm38)	S395A	possibly damaging	Het
Ppp1r18	A	G	17: 35,867,284 (GRCm38)	Q17R	probably damaging	Het
Prokr2	A	T	2: 132,374,076 (GRCm38)	V155D	probably damaging	Het
Pwwp2a	T	G	11: 43,705,869 (GRCm38)	C620W	probably damaging	Het
Rabepk	T	C	2: 34,785,593 (GRCm38)	D175G	probably damaging	Het
Rad54l	T	C	4: 116,099,669 (GRCm38)	Y485C	probably damaging	Het
Rasef	A	G	4: 73,734,534 (GRCm38)	S577P	probably damaging	Het
Rgma	C	A	7: 73,418,004 (GRCm38)	L446I	unknown	Het
Rnf212b	T	C	14: 54,842,368 (GRCm38)	S182P	probably damaging	Het
Rnf6	C	A	5: 146,211,176 (GRCm38)	R344I	probably damaging	Het
Rnf6	T	A	5: 146,211,177 (GRCm38)	R344*	probably null	Het
Sgo1	A	G	17: 53,679,611 (GRCm38)	I184T	possibly damaging	Het
Sgpl1	A	T	10: 61,117,723 (GRCm38)	I78N	possibly damaging	Het
Snx13	T	A	12: 35,107,484 (GRCm38)	Y510N	probably damaging	Het
Sptbn2	G	A	19: 4,734,143 (GRCm38)	E638K	possibly damaging	Het
Sspo	A	G	6: 48,451,382 (GRCm38)	T349A	probably damaging	Het
Sv2c	C	T	13: 95,989,715 (GRCm38)	S343N	probably damaging	Het
Syne1	T	A	10: 5,333,632 (GRCm38)	I1478F	possibly damaging	Het
Syne1	C	A	10: 5,333,560 (GRCm38)	V1502F	possibly damaging	Het
Tmem121	C	T	12: 113,188,372 (GRCm38)	A70V	probably damaging	Het
Tmem215	A	G	4: 40,474,042 (GRCm38)	I40V	possibly damaging	Het
Trim25	A	G	11: 89,009,117 (GRCm38)		probably null	Het
Trio	A	G	15: 27,889,418 (GRCm38)	V534A	unknown	Het
Tyr	T	A	7: 87,493,010 (GRCm38)	E114V	probably benign	Het
Ush2a	A	T	1: 188,553,260 (GRCm38)	T1998S	probably benign	Het
Usp40	G	T	1: 87,982,178 (GRCm38)	A518E	probably benign	Het
Usp48	T	A	4: 137,604,645 (GRCm38)		probably null	Het
Vash1	T	A	12: 86,686,993 (GRCm38)	F152L	probably damaging	Het
Vsig10l	C	A	7: 43,463,717 (GRCm38)	P31Q	probably damaging	Het
Xab2	C	T	8: 3,619,018 (GRCm38)	E43K	probably benign	Het
Zfp423	G	A	8: 87,780,884 (GRCm38)	S944F	probably damaging	Het
Zp2	A	T	7: 120,137,169 (GRCm38)	D350E	probably benign	Het
Zscan4e	T	G	7: 11,307,534 (GRCm38)	Q165P	probably damaging	Het

Other mutations in Dnhd1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00321:Dnhd1	APN	7	105,677,995 (GRCm38)	missense	probably damaging	1.00
IGL00516:Dnhd1	APN	7	105,657,211 (GRCm38)	missense	possibly damaging	0.52
IGL00576:Dnhd1	APN	7	105,692,675 (GRCm38)	missense	probably damaging	1.00
IGL00990:Dnhd1	APN	7	105,721,688 (GRCm38)	missense	possibly damaging	0.85
IGL01346:Dnhd1	APN	7	105,713,909 (GRCm38)	missense	probably benign
IGL01714:Dnhd1	APN	7	105,720,942 (GRCm38)	missense	probably damaging	1.00
IGL01735:Dnhd1	APN	7	105,713,754 (GRCm38)	missense	probably benign	0.37
IGL01814:Dnhd1	APN	7	105,652,030 (GRCm38)	missense	probably benign
IGL01999:Dnhd1	APN	7	105,721,215 (GRCm38)	missense	possibly damaging	0.50
IGL02022:Dnhd1	APN	7	105,678,309 (GRCm38)	missense	probably damaging	1.00
IGL02131:Dnhd1	APN	7	105,720,802 (GRCm38)	missense	probably damaging	1.00
IGL02156:Dnhd1	APN	7	105,721,744 (GRCm38)	missense	probably damaging	1.00
IGL02674:Dnhd1	APN	7	105,721,481 (GRCm38)	missense	probably benign	0.00
IGL02966:Dnhd1	APN	7	105,720,741 (GRCm38)	missense	probably benign	0.00
IGL03066:Dnhd1	APN	7	105,719,882 (GRCm38)	missense	probably damaging	0.99
IGL03298:Dnhd1	APN	7	105,714,475 (GRCm38)	missense	probably damaging	0.98
IGL03378:Dnhd1	APN	7	105,713,733 (GRCm38)	missense	possibly damaging	0.87
IGL02802:Dnhd1	UTSW	7	105,655,723 (GRCm38)	missense	possibly damaging	0.83
R0060:Dnhd1	UTSW	7	105,668,514 (GRCm38)	missense	probably damaging	0.99
R0129:Dnhd1	UTSW	7	105,720,924 (GRCm38)	missense	probably benign	0.19
R0238:Dnhd1	UTSW	7	105,721,531 (GRCm38)	missense	probably benign	0.06
R0238:Dnhd1	UTSW	7	105,721,531 (GRCm38)	missense	probably benign	0.06
R0239:Dnhd1	UTSW	7	105,721,531 (GRCm38)	missense	probably benign	0.06
R0239:Dnhd1	UTSW	7	105,721,531 (GRCm38)	missense	probably benign	0.06
R0384:Dnhd1	UTSW	7	105,720,114 (GRCm38)	missense	possibly damaging	0.56
R0453:Dnhd1	UTSW	7	105,674,444 (GRCm38)	missense	probably benign	0.00
R0540:Dnhd1	UTSW	7	105,720,788 (GRCm38)	missense	probably benign	0.04
R0554:Dnhd1	UTSW	7	105,694,395 (GRCm38)	missense	probably benign	0.10
R0576:Dnhd1	UTSW	7	105,714,045 (GRCm38)	missense	probably damaging	1.00
R0607:Dnhd1	UTSW	7	105,720,788 (GRCm38)	missense	probably benign	0.04
R0631:Dnhd1	UTSW	7	105,651,624 (GRCm38)	missense	probably benign	0.17
R0639:Dnhd1	UTSW	7	105,696,464 (GRCm38)	missense	possibly damaging	0.95
R0668:Dnhd1	UTSW	7	105,695,751 (GRCm38)	missense	probably benign
R0669:Dnhd1	UTSW	7	105,693,704 (GRCm38)	missense	probably benign	0.01
R0670:Dnhd1	UTSW	7	105,696,464 (GRCm38)	missense	possibly damaging	0.95
R0699:Dnhd1	UTSW	7	105,651,906 (GRCm38)	missense	probably damaging	0.98
R1019:Dnhd1	UTSW	7	105,709,171 (GRCm38)	missense	probably damaging	1.00
R1144:Dnhd1	UTSW	7	105,713,031 (GRCm38)	missense	probably damaging	1.00
R1226:Dnhd1	UTSW	7	105,696,899 (GRCm38)	missense	probably damaging	1.00
R1257:Dnhd1	UTSW	7	105,694,153 (GRCm38)	missense	probably damaging	1.00
R1391:Dnhd1	UTSW	7	105,720,124 (GRCm38)	missense	probably damaging	1.00
R1453:Dnhd1	UTSW	7	105,721,273 (GRCm38)	critical splice donor site	probably null
R1501:Dnhd1	UTSW	7	105,668,463 (GRCm38)	missense	probably benign	0.00
R1503:Dnhd1	UTSW	7	105,693,660 (GRCm38)	missense	possibly damaging	0.67
R1515:Dnhd1	UTSW	7	105,704,148 (GRCm38)	missense	probably benign	0.11
R1615:Dnhd1	UTSW	7	105,713,706 (GRCm38)	missense	possibly damaging	0.74
R1615:Dnhd1	UTSW	7	105,703,206 (GRCm38)	missense	probably benign	0.00
R1656:Dnhd1	UTSW	7	105,714,281 (GRCm38)	missense	probably damaging	1.00
R1720:Dnhd1	UTSW	7	105,693,828 (GRCm38)	missense	probably benign
R1723:Dnhd1	UTSW	7	105,714,920 (GRCm38)	missense	possibly damaging	0.60
R1766:Dnhd1	UTSW	7	105,693,972 (GRCm38)	missense	possibly damaging	0.50
R1799:Dnhd1	UTSW	7	105,655,767 (GRCm38)	missense	probably benign	0.31
R1860:Dnhd1	UTSW	7	105,704,205 (GRCm38)	missense	probably benign
R1920:Dnhd1	UTSW	7	105,713,407 (GRCm38)	missense	probably benign	0.00
R1925:Dnhd1	UTSW	7	105,673,854 (GRCm38)	missense	probably damaging	0.96
R1925:Dnhd1	UTSW	7	105,652,252 (GRCm38)	missense	probably damaging	1.00
R1934:Dnhd1	UTSW	7	105,708,582 (GRCm38)	missense	probably benign	0.05
R1935:Dnhd1	UTSW	7	105,673,976 (GRCm38)	missense	probably benign	0.09
R1936:Dnhd1	UTSW	7	105,673,976 (GRCm38)	missense	probably benign	0.09
R2035:Dnhd1	UTSW	7	105,704,921 (GRCm38)	missense	probably damaging	0.99
R2125:Dnhd1	UTSW	7	105,677,971 (GRCm38)	missense	probably benign	0.35
R2127:Dnhd1	UTSW	7	105,693,721 (GRCm38)	missense	possibly damaging	0.56
R2254:Dnhd1	UTSW	7	105,703,772 (GRCm38)	missense	probably damaging	1.00
R2301:Dnhd1	UTSW	7	105,705,399 (GRCm38)	missense	probably damaging	1.00
R2316:Dnhd1	UTSW	7	105,674,421 (GRCm38)	missense	probably damaging	1.00
R2324:Dnhd1	UTSW	7	105,710,090 (GRCm38)	missense	probably damaging	1.00
R2337:Dnhd1	UTSW	7	105,703,467 (GRCm38)	missense	probably benign	0.07
R2381:Dnhd1	UTSW	7	105,693,664 (GRCm38)	missense	probably benign	0.42
R2394:Dnhd1	UTSW	7	105,720,231 (GRCm38)	missense	probably benign	0.19
R2862:Dnhd1	UTSW	7	105,712,559 (GRCm38)	missense	probably benign	0.01
R3038:Dnhd1	UTSW	7	105,720,229 (GRCm38)	missense	probably damaging	0.99
R3114:Dnhd1	UTSW	7	105,696,565 (GRCm38)	critical splice donor site	probably null
R3404:Dnhd1	UTSW	7	105,694,761 (GRCm38)	nonsense	probably null
R3405:Dnhd1	UTSW	7	105,694,761 (GRCm38)	nonsense	probably null
R3439:Dnhd1	UTSW	7	105,694,785 (GRCm38)	missense	probably damaging	1.00
R3959:Dnhd1	UTSW	7	105,713,122 (GRCm38)	missense	probably benign	0.21
R4014:Dnhd1	UTSW	7	105,714,838 (GRCm38)	missense	probably damaging	0.99
R4084:Dnhd1	UTSW	7	105,709,588 (GRCm38)	missense	probably damaging	1.00
R4181:Dnhd1	UTSW	7	105,693,954 (GRCm38)	missense	probably damaging	1.00
R4255:Dnhd1	UTSW	7	105,712,998 (GRCm38)	missense	probably damaging	1.00
R4302:Dnhd1	UTSW	7	105,693,954 (GRCm38)	missense	probably damaging	1.00
R4440:Dnhd1	UTSW	7	105,696,728 (GRCm38)	nonsense	probably null
R4565:Dnhd1	UTSW	7	105,651,956 (GRCm38)	missense	possibly damaging	0.92
R4569:Dnhd1	UTSW	7	105,657,166 (GRCm38)	splice site	probably null
R4584:Dnhd1	UTSW	7	105,678,049 (GRCm38)	missense	probably damaging	1.00
R4586:Dnhd1	UTSW	7	105,678,049 (GRCm38)	missense	probably damaging	1.00
R4590:Dnhd1	UTSW	7	105,714,030 (GRCm38)	missense	probably damaging	1.00
R4593:Dnhd1	UTSW	7	105,715,446 (GRCm38)	missense	probably benign	0.02
R4600:Dnhd1	UTSW	7	105,703,644 (GRCm38)	missense	probably damaging	1.00
R4705:Dnhd1	UTSW	7	105,655,741 (GRCm38)	missense	probably damaging	1.00
R4731:Dnhd1	UTSW	7	105,673,849 (GRCm38)	missense	probably benign	0.00
R4732:Dnhd1	UTSW	7	105,673,849 (GRCm38)	missense	probably benign	0.00
R4733:Dnhd1	UTSW	7	105,673,849 (GRCm38)	missense	probably benign	0.00
R4786:Dnhd1	UTSW	7	105,674,444 (GRCm38)	missense	probably benign	0.00
R4791:Dnhd1	UTSW	7	105,721,117 (GRCm38)	missense	probably damaging	1.00
R4811:Dnhd1	UTSW	7	105,714,281 (GRCm38)	missense	probably damaging	0.99
R4822:Dnhd1	UTSW	7	105,703,964 (GRCm38)	missense	probably benign	0.00
R4886:Dnhd1	UTSW	7	105,714,808 (GRCm38)	missense	probably benign	0.00
R4890:Dnhd1	UTSW	7	105,656,957 (GRCm38)	missense	possibly damaging	0.47
R4973:Dnhd1	UTSW	7	105,713,633 (GRCm38)	missense	probably benign	0.24
R5007:Dnhd1	UTSW	7	105,713,076 (GRCm38)	missense	probably damaging	1.00
R5048:Dnhd1	UTSW	7	105,693,697 (GRCm38)	missense	probably benign	0.01
R5151:Dnhd1	UTSW	7	105,713,440 (GRCm38)	missense	probably benign	0.22
R5179:Dnhd1	UTSW	7	105,714,552 (GRCm38)	missense	probably damaging	1.00
R5182:Dnhd1	UTSW	7	105,703,209 (GRCm38)	missense	probably damaging	1.00
R5183:Dnhd1	UTSW	7	105,703,209 (GRCm38)	missense	probably damaging	1.00
R5185:Dnhd1	UTSW	7	105,703,209 (GRCm38)	missense	probably damaging	1.00
R5209:Dnhd1	UTSW	7	105,696,460 (GRCm38)	missense	probably benign	0.00
R5225:Dnhd1	UTSW	7	105,703,923 (GRCm38)	missense	possibly damaging	0.73
R5250:Dnhd1	UTSW	7	105,685,761 (GRCm38)	missense	probably damaging	1.00
R5257:Dnhd1	UTSW	7	105,674,037 (GRCm38)	missense	probably benign
R5258:Dnhd1	UTSW	7	105,674,037 (GRCm38)	missense	probably benign
R5273:Dnhd1	UTSW	7	105,714,482 (GRCm38)	missense	probably damaging	0.99
R5288:Dnhd1	UTSW	7	105,714,437 (GRCm38)	missense	possibly damaging	0.94
R5396:Dnhd1	UTSW	7	105,713,684 (GRCm38)	missense	probably benign	0.00
R5453:Dnhd1	UTSW	7	105,710,123 (GRCm38)	missense	probably damaging	1.00
R5511:Dnhd1	UTSW	7	105,714,156 (GRCm38)	missense	probably damaging	1.00
R5518:Dnhd1	UTSW	7	105,703,209 (GRCm38)	missense	probably damaging	1.00
R5523:Dnhd1	UTSW	7	105,703,209 (GRCm38)	missense	probably damaging	1.00
R5528:Dnhd1	UTSW	7	105,703,209 (GRCm38)	missense	probably damaging	1.00
R5529:Dnhd1	UTSW	7	105,703,209 (GRCm38)	missense	probably damaging	1.00
R5561:Dnhd1	UTSW	7	105,714,821 (GRCm38)	missense	probably damaging	0.99
R5681:Dnhd1	UTSW	7	105,703,209 (GRCm38)	missense	probably damaging	1.00
R5682:Dnhd1	UTSW	7	105,703,209 (GRCm38)	missense	probably damaging	1.00
R5683:Dnhd1	UTSW	7	105,703,209 (GRCm38)	missense	probably damaging	1.00
R5684:Dnhd1	UTSW	7	105,703,209 (GRCm38)	missense	probably damaging	1.00
R5686:Dnhd1	UTSW	7	105,703,209 (GRCm38)	missense	probably damaging	1.00
R5697:Dnhd1	UTSW	7	105,674,188 (GRCm38)	missense	probably damaging	1.00
R5789:Dnhd1	UTSW	7	105,705,010 (GRCm38)	missense	possibly damaging	0.50
R5790:Dnhd1	UTSW	7	105,655,774 (GRCm38)	missense	probably damaging	1.00
R5814:Dnhd1	UTSW	7	105,719,895 (GRCm38)	missense	possibly damaging	0.69
R5828:Dnhd1	UTSW	7	105,720,181 (GRCm38)	missense	probably benign	0.00
R5852:Dnhd1	UTSW	7	105,695,748 (GRCm38)	missense	probably damaging	1.00
R5883:Dnhd1	UTSW	7	105,720,504 (GRCm38)	missense	probably damaging	0.98
R6115:Dnhd1	UTSW	7	105,713,987 (GRCm38)	missense	probably benign	0.00
R6119:Dnhd1	UTSW	7	105,709,440 (GRCm38)	missense	probably benign	0.18
R6212:Dnhd1	UTSW	7	105,704,048 (GRCm38)	missense	probably damaging	1.00
R6243:Dnhd1	UTSW	7	105,652,009 (GRCm38)	missense	probably damaging	1.00
R6265:Dnhd1	UTSW	7	105,693,370 (GRCm38)	missense	probably benign	0.07
R6332:Dnhd1	UTSW	7	105,694,066 (GRCm38)	missense	probably benign	0.02
R6344:Dnhd1	UTSW	7	105,694,610 (GRCm38)	missense	probably benign	0.38
R6477:Dnhd1	UTSW	7	105,677,886 (GRCm38)	missense	probably benign	0.05
R6642:Dnhd1	UTSW	7	105,703,799 (GRCm38)	missense	probably benign
R6663:Dnhd1	UTSW	7	105,685,692 (GRCm38)	splice site	probably null
R6730:Dnhd1	UTSW	7	105,703,875 (GRCm38)	missense	probably benign	0.00
R6748:Dnhd1	UTSW	7	105,720,637 (GRCm38)	missense	probably benign	0.03
R6833:Dnhd1	UTSW	7	105,703,373 (GRCm38)	missense	probably benign	0.01
R6850:Dnhd1	UTSW	7	105,719,930 (GRCm38)	missense	possibly damaging	0.68
R6853:Dnhd1	UTSW	7	105,703,728 (GRCm38)	missense	probably benign
R6860:Dnhd1	UTSW	7	105,678,266 (GRCm38)	missense	probably benign
R6898:Dnhd1	UTSW	7	105,687,377 (GRCm38)	missense	probably damaging	0.99
R6927:Dnhd1	UTSW	7	105,715,563 (GRCm38)	missense	probably damaging	1.00
R6952:Dnhd1	UTSW	7	105,713,688 (GRCm38)	missense	probably damaging	1.00
R6987:Dnhd1	UTSW	7	105,704,585 (GRCm38)	missense	probably damaging	0.98
R6988:Dnhd1	UTSW	7	105,714,210 (GRCm38)	missense	probably damaging	1.00
R7022:Dnhd1	UTSW	7	105,720,798 (GRCm38)	missense	probably benign	0.36
R7053:Dnhd1	UTSW	7	105,694,954 (GRCm38)	missense	probably damaging	1.00
R7085:Dnhd1	UTSW	7	105,715,261 (GRCm38)	missense	probably benign	0.26
R7086:Dnhd1	UTSW	7	105,708,532 (GRCm38)	missense	probably benign	0.03
R7112:Dnhd1	UTSW	7	105,713,985 (GRCm38)	missense	probably damaging	1.00
R7140:Dnhd1	UTSW	7	105,693,766 (GRCm38)	missense	probably benign	0.00
R7151:Dnhd1	UTSW	7	105,710,027 (GRCm38)	missense	probably benign	0.03
R7178:Dnhd1	UTSW	7	105,694,993 (GRCm38)	missense	probably damaging	0.98
R7326:Dnhd1	UTSW	7	105,720,930 (GRCm38)	missense	probably damaging	0.96
R7345:Dnhd1	UTSW	7	105,703,967 (GRCm38)	missense	probably benign	0.17
R7349:Dnhd1	UTSW	7	105,710,123 (GRCm38)	missense	probably damaging	1.00
R7397:Dnhd1	UTSW	7	105,705,297 (GRCm38)	missense	possibly damaging	0.87
R7520:Dnhd1	UTSW	7	105,696,048 (GRCm38)	missense	probably benign	0.07
R7536:Dnhd1	UTSW	7	105,709,561 (GRCm38)	missense	probably damaging	1.00
R7539:Dnhd1	UTSW	7	105,720,912 (GRCm38)	missense	probably damaging	1.00
R7541:Dnhd1	UTSW	7	105,678,309 (GRCm38)	missense	probably damaging	1.00
R7619:Dnhd1	UTSW	7	105,674,268 (GRCm38)	missense	probably benign	0.01
R7676:Dnhd1	UTSW	7	105,684,087 (GRCm38)	missense	probably benign	0.09
R7689:Dnhd1	UTSW	7	105,713,963 (GRCm38)	missense	probably benign	0.07
R7712:Dnhd1	UTSW	7	105,651,624 (GRCm38)	missense	probably benign	0.17
R7729:Dnhd1	UTSW	7	105,705,265 (GRCm38)	missense	probably damaging	1.00
R7768:Dnhd1	UTSW	7	105,721,095 (GRCm38)	missense	possibly damaging	0.87
R7779:Dnhd1	UTSW	7	105,677,915 (GRCm38)	missense	probably benign	0.01
R7879:Dnhd1	UTSW	7	105,703,439 (GRCm38)	missense	probably benign	0.09
R7922:Dnhd1	UTSW	7	105,668,514 (GRCm38)	missense	probably damaging	1.00
R7951:Dnhd1	UTSW	7	105,678,004 (GRCm38)	missense	probably damaging	1.00
R8259:Dnhd1	UTSW	7	105,694,788 (GRCm38)	missense	probably benign	0.38
R8350:Dnhd1	UTSW	7	105,678,024 (GRCm38)	missense	probably damaging	0.99
R8380:Dnhd1	UTSW	7	105,677,866 (GRCm38)	missense	probably benign	0.31
R8392:Dnhd1	UTSW	7	105,703,343 (GRCm38)	missense	possibly damaging	0.84
R8478:Dnhd1	UTSW	7	105,682,794 (GRCm38)	missense	probably benign	0.00
R8708:Dnhd1	UTSW	7	105,694,280 (GRCm38)	nonsense	probably null
R8767:Dnhd1	UTSW	7	105,652,123 (GRCm38)	missense	probably damaging	1.00
R8825:Dnhd1	UTSW	7	105,693,967 (GRCm38)	missense	possibly damaging	0.95
R8849:Dnhd1	UTSW	7	105,721,516 (GRCm38)	missense	probably benign	0.00
R8903:Dnhd1	UTSW	7	105,713,648 (GRCm38)	nonsense	probably null
R8910:Dnhd1	UTSW	7	105,683,697 (GRCm38)	missense	possibly damaging	0.92
R8940:Dnhd1	UTSW	7	105,714,647 (GRCm38)	intron	probably benign
R8954:Dnhd1	UTSW	7	105,694,779 (GRCm38)	missense	probably benign	0.35
R8956:Dnhd1	UTSW	7	105,692,645 (GRCm38)	missense	probably damaging	0.99
R8971:Dnhd1	UTSW	7	105,709,321 (GRCm38)	nonsense	probably null
R8996:Dnhd1	UTSW	7	105,674,035 (GRCm38)	missense	probably damaging	1.00
R9051:Dnhd1	UTSW	7	105,692,726 (GRCm38)	missense	possibly damaging	0.54
R9058:Dnhd1	UTSW	7	105,684,063 (GRCm38)	missense	probably benign	0.01
R9109:Dnhd1	UTSW	7	105,683,966 (GRCm38)	missense	probably damaging	0.98
R9284:Dnhd1	UTSW	7	105,651,884 (GRCm38)	missense	probably damaging	1.00
R9295:Dnhd1	UTSW	7	105,714,141 (GRCm38)	missense	probably benign
R9298:Dnhd1	UTSW	7	105,683,966 (GRCm38)	missense	probably damaging	0.98
R9299:Dnhd1	UTSW	7	105,720,599 (GRCm38)	missense	probably benign	0.00
R9308:Dnhd1	UTSW	7	105,704,277 (GRCm38)	missense	probably damaging	1.00
R9337:Dnhd1	UTSW	7	105,720,599 (GRCm38)	missense	probably benign	0.00
R9385:Dnhd1	UTSW	7	105,712,765 (GRCm38)	missense	probably damaging	1.00
R9463:Dnhd1	UTSW	7	105,695,016 (GRCm38)	missense	probably benign
R9463:Dnhd1	UTSW	7	105,657,247 (GRCm38)	missense	probably benign	0.00
R9476:Dnhd1	UTSW	7	105,703,682 (GRCm38)	missense	possibly damaging	0.74
R9489:Dnhd1	UTSW	7	105,651,597 (GRCm38)	missense	probably benign
R9500:Dnhd1	UTSW	7	105,704,502 (GRCm38)	missense	probably benign
R9510:Dnhd1	UTSW	7	105,703,682 (GRCm38)	missense	possibly damaging	0.74
R9513:Dnhd1	UTSW	7	105,704,972 (GRCm38)	missense	probably damaging	1.00
R9537:Dnhd1	UTSW	7	105,695,533 (GRCm38)	missense	probably damaging	0.99
R9567:Dnhd1	UTSW	7	105,704,266 (GRCm38)	missense	probably benign	0.03
R9622:Dnhd1	UTSW	7	105,704,135 (GRCm38)	missense	probably benign
R9623:Dnhd1	UTSW	7	105,694,927 (GRCm38)	missense	probably damaging	1.00
R9623:Dnhd1	UTSW	7	105,686,566 (GRCm38)	missense	probably damaging	1.00
R9674:Dnhd1	UTSW	7	105,714,222 (GRCm38)	missense	probably damaging	1.00
R9756:Dnhd1	UTSW	7	105,703,928 (GRCm38)	missense	probably benign	0.19
R9777:Dnhd1	UTSW	7	105,720,249 (GRCm38)	missense	probably benign	0.14
R9778:Dnhd1	UTSW	7	105,704,033 (GRCm38)	missense	probably benign
R9781:Dnhd1	UTSW	7	105,703,710 (GRCm38)	missense	probably benign	0.31
R9796:Dnhd1	UTSW	7	105,693,330 (GRCm38)	missense	probably damaging	1.00
Z1088:Dnhd1	UTSW	7	105,712,727 (GRCm38)	missense	probably benign	0.00
Z1176:Dnhd1	UTSW	7	105,703,036 (GRCm38)	critical splice acceptor site	probably null
Z1176:Dnhd1	UTSW	7	105,678,299 (GRCm38)	missense	probably benign
Z1176:Dnhd1	UTSW	7	105,668,547 (GRCm38)	missense	probably damaging	0.98
Z1176:Dnhd1	UTSW	7	105,703,580 (GRCm38)	frame shift	probably null
Z1177:Dnhd1	UTSW	7	105,682,841 (GRCm38)	missense	possibly damaging	0.90

Predicted Primers

PCR Primer
(F):5'- ACCTAGCCTGATGCATGAGC -3'
(R):5'- GACACTTGATGCTTCTCAAAGAAAC -3'

Sequencing Primer
(F):5'- GCATGAGCGTCAAGTATTTATTCTC -3'
(R):5'- CACCACCAAGGAGTAGGGGTTTAG -3'

Posted On

2019-11-26