Mutagenetix > Incidental Mutation

Incidental Mutation 'R7768:Celsr1'

598416

Institutional Source

Beutler Lab

Gene Symbol

Celsr1

Ensembl Gene

ENSMUSG00000016028

Gene Name

cadherin, EGF LAG seven-pass G-type receptor 1

Synonyms

Scy, Adgrc1, Crsh, crash

MMRRC Submission

045824-MU

Accession Numbers

Essential gene?

Possibly essential (E-score: 0.634) question?

Stock #

R7768 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

85783130-85918404 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

G to T at 85816610 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Glutamine to Lysine at position 1778 (Q1778K)

Ref Sequence

ENSEMBL: ENSMUSP00000016172 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000016172]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000016172
AA Change: Q1778K

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000016172
Gene: ENSMUSG00000016028
AA Change: Q1778K

Domain	Start	End	E-Value	Type
signal peptide	1	29	N/A	INTRINSIC
low complexity region	65	93	N/A	INTRINSIC
low complexity region	221	240	N/A	INTRINSIC
low complexity region	243	257	N/A	INTRINSIC
CA	282	366	9.51e-26	SMART
CA	390	472	1.59e-27	SMART
CA	496	578	3.8e-25	SMART
CA	602	700	2.25e-27	SMART
CA	724	802	3.14e-17	SMART
CA	826	905	2.67e-29	SMART
CA	929	1012	3.23e-28	SMART
CA	1036	1114	4.17e-22	SMART
CA	1142	1218	6.89e-1	SMART
EGF	1321	1376	3.38e-3	SMART
EGF	1381	1414	5.49e-3	SMART
EGF	1421	1456	9.7e-4	SMART
LamG	1477	1644	2.53e-33	SMART
EGF	1667	1700	6.4e-4	SMART
LamG	1726	1864	1.13e-21	SMART
EGF	1890	1923	1.84e-4	SMART
EGF	1925	1961	5.49e-3	SMART
EGF_Lam	2018	2063	7.12e-11	SMART
HormR	2066	2128	2.55e-20	SMART
Pfam:GAIN	2140	2396	1.1e-64	PFAM
GPS	2422	2475	5.03e-22	SMART
Pfam:7tm_2	2480	2712	2.6e-60	PFAM
low complexity region	2738	2753	N/A	INTRINSIC
low complexity region	2819	2852	N/A	INTRINSIC
low complexity region	2976	2988	N/A	INTRINSIC

Predicted Effect

Coding Region Coverage

1x: 100.0%
3x: 100.0%
10x: 99.7%
20x: 99.1%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. This particular member is a developmentally regulated, neural-specific gene which plays an unspecified role in early embryogenesis. [provided by RefSeq, Jul 2008]
PHENOTYPE: Nullizygous mice exhibit kinky tails, variable neural tube defects, abnormal hair follicle orientation, whorl-like hair patterns, and partial prenatal lethality. ENU-induced mutants show defects in planar polarity of inner ear hair cells and complete perinatal lethality due to craniorachischisis. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 87 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Actn2	A	G	13: 12,297,480 (GRCm39)	V479A	possibly damaging	Het
Acy1	G	A	9: 106,310,817 (GRCm39)	T317M	possibly damaging	Het
Adgrg6	A	T	10: 14,307,410 (GRCm39)	D797E	probably benign	Het
Ank1	C	T	8: 23,588,013 (GRCm39)	A552V	probably benign	Het
Ankrd13c	A	G	3: 157,694,284 (GRCm39)	T262A	probably benign	Het
Ap4e1	A	T	2: 126,888,854 (GRCm39)	N468Y	probably damaging	Het
Apbb1	T	C	7: 105,216,295 (GRCm39)	I367V	probably benign	Het
Arl6	A	G	16: 59,452,699 (GRCm39)	I33T	probably damaging	Het
Asgr2	T	C	11: 69,996,242 (GRCm39)	I228T	probably damaging	Het
Aspn	A	G	13: 49,710,871 (GRCm39)	H172R	probably damaging	Het
Bclaf1	T	A	10: 20,215,517 (GRCm39)	F868L	probably benign	Het
Cacna1i	G	A	15: 80,265,389 (GRCm39)	R1547H	probably damaging	Het
Cep250	T	C	2: 155,827,929 (GRCm39)	L42S		Het
Clnk	C	A	5: 38,925,501 (GRCm39)	R100L	probably damaging	Het
Cpvl	A	G	6: 53,873,476 (GRCm39)	V420A	possibly damaging	Het
Dicer1	C	A	12: 104,672,956 (GRCm39)	G825V	probably damaging	Het
Dmxl2	T	C	9: 54,288,223 (GRCm39)	Y2628C	probably damaging	Het
Dnah7b	T	A	1: 46,176,634 (GRCm39)	H751Q	probably benign	Het
Dnhd1	C	A	7: 105,370,302 (GRCm39)	R4576S	possibly damaging	Het
Dzip1	A	T	14: 119,116,910 (GRCm39)	D775E	probably benign	Het
Erich3	T	A	3: 154,453,968 (GRCm39)	M381K	probably benign	Het
Fam193a	A	G	5: 34,623,135 (GRCm39)	D1241G	possibly damaging	Het
Gbx2	A	G	1: 89,856,706 (GRCm39)	L228P	probably benign	Het
Ggt7	A	T	2: 155,348,421 (GRCm39)	M77K	possibly damaging	Het
Gpr26	T	A	7: 131,576,077 (GRCm39)	I247K	probably damaging	Het
Grip1	A	G	10: 119,874,302 (GRCm39)	T745A	probably damaging	Het
Gusb	A	T	5: 130,029,246 (GRCm39)	H178Q	probably benign	Het
Hacl1	T	C	14: 31,338,437 (GRCm39)	Y380C	probably damaging	Het
Hdac9	T	C	12: 34,440,239 (GRCm39)	H380R	possibly damaging	Het
Icam4	T	A	9: 20,941,290 (GRCm39)	L143Q	probably damaging	Het
Ikbkb	T	A	8: 23,185,252 (GRCm39)	I43F	probably damaging	Het
Ints11	G	T	4: 155,971,396 (GRCm39)	K303N	probably damaging	Het
Itpa	A	T	2: 130,509,836 (GRCm39)	N16I	probably damaging	Het
Kank1	GCGAACG	GCG	19: 25,388,569 (GRCm39)		probably null	Het
Kat6a	T	A	8: 23,393,228 (GRCm39)	N235K	probably damaging	Het
Kmt2a	C	T	9: 44,731,900 (GRCm39)	V2806I	unknown	Het
Loxhd1	T	A	18: 77,472,637 (GRCm39)	F1051L	probably damaging	Het
Map2	A	G	1: 66,453,642 (GRCm39)	E844G	possibly damaging	Het
Mmp7	T	A	9: 7,697,749 (GRCm39)	Y261*	probably null	Het
Muc4	A	C	16: 32,576,568 (GRCm39)	M2023L	unknown	Het
Mybpc1	C	A	10: 88,378,234 (GRCm39)	G688V	probably damaging	Het
Myo3a	A	G	2: 22,245,954 (GRCm39)	T34A	probably damaging	Het
Nrxn2	A	G	19: 6,531,409 (GRCm39)	T683A	possibly damaging	Het
Nup160	A	G	2: 90,530,460 (GRCm39)	I444V	probably damaging	Het
Or2t29	A	T	11: 58,433,466 (GRCm39)	S292T	probably damaging	Het
Or2t29	A	T	11: 58,433,693 (GRCm39)	M216K	possibly damaging	Het
Or4f4-ps1	A	C	2: 111,330,198 (GRCm39)	K200N	possibly damaging	Het
Or8w1	T	C	2: 87,465,657 (GRCm39)	M145V	probably benign	Het
Pcdha1	A	G	18: 37,065,220 (GRCm39)	E628G	probably damaging	Het
Pcdha12	T	C	18: 37,155,404 (GRCm39)	S708P	probably damaging	Het
Pira2	A	T	7: 3,844,696 (GRCm39)	F445Y	probably benign	Het
Pkd1l2	A	G	8: 117,781,599 (GRCm39)		probably null	Het
Pla2g6	T	C	15: 79,181,514 (GRCm39)	D577G	probably damaging	Het
Pla2r1	G	T	2: 60,279,290 (GRCm39)	D763E	probably benign	Het
Pramel18	A	C	4: 101,769,010 (GRCm39)	I454L	probably benign	Het
Psg18	A	T	7: 18,079,953 (GRCm39)	I416N	probably damaging	Het
Rapgef6	G	T	11: 54,517,414 (GRCm39)	V369F	probably damaging	Het
Rasal3	T	C	17: 32,615,767 (GRCm39)	E357G	probably damaging	Het
Rhbdl3	G	A	11: 80,221,447 (GRCm39)	R195Q	probably benign	Het
Rnf216	A	T	5: 143,084,199 (GRCm39)	M1K	probably null	Het
Rspry1	C	A	8: 95,356,469 (GRCm39)	D165E	probably damaging	Het
Rwdd2b	G	A	16: 87,233,633 (GRCm39)	L156F	probably benign	Het
Scn11a	T	A	9: 119,644,338 (GRCm39)	I141F	probably benign	Het
Sirt2	A	T	7: 28,482,284 (GRCm39)	T198S	probably benign	Het
Slc2a1	A	G	4: 118,989,644 (GRCm39)	N94D	probably damaging	Het
Slc33a1	A	G	3: 63,855,039 (GRCm39)	F407S	possibly damaging	Het
Slc38a4	A	C	15: 96,906,545 (GRCm39)	L356R	probably damaging	Het
Slc43a1	T	A	2: 84,687,215 (GRCm39)	L372Q	probably damaging	Het
Slc6a6	T	A	6: 91,716,946 (GRCm39)	I274N	probably damaging	Het
Smchd1	C	T	17: 71,718,906 (GRCm39)	G821D	probably damaging	Het
Spata33	T	C	8: 123,941,146 (GRCm39)	F65S	unknown	Het
Spmip5	A	T	19: 58,781,174 (GRCm39)	Y25N	probably damaging	Het
Stx19	A	G	16: 62,642,567 (GRCm39)	T128A	probably benign	Het
Tas2r103	T	C	6: 133,013,812 (GRCm39)	M85V	probably benign	Het
Tas2r117	C	T	6: 132,780,485 (GRCm39)	L208F	probably damaging	Het
Tcirg1	A	T	19: 3,952,900 (GRCm39)	I233N	possibly damaging	Het
Uba6	C	A	5: 86,300,779 (GRCm39)	W192L	probably benign	Het
Ube3a	T	C	7: 58,938,525 (GRCm39)	I761T	probably damaging	Het
Unc80	T	C	1: 66,549,754 (GRCm39)	S671P	possibly damaging	Het
Usp8	A	G	2: 126,593,043 (GRCm39)	Q766R	probably damaging	Het
Vmn2r103	A	G	17: 20,032,314 (GRCm39)	N696S	probably damaging	Het
Vmn2r14	G	A	5: 109,368,086 (GRCm39)	T302I	probably benign	Het
Vmn2r50	G	A	7: 9,771,298 (GRCm39)	A801V	probably damaging	Het
Vmn2r85	T	G	10: 130,254,562 (GRCm39)	Q707H	probably damaging	Het
Wsb2	G	A	5: 117,501,787 (GRCm39)	V51M	probably benign	Het
Xdh	T	C	17: 74,246,831 (GRCm39)	T78A	probably benign	Het
Zfp442	T	C	2: 150,250,241 (GRCm39)	K554E	possibly damaging	Het

Other mutations in Celsr1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00392:Celsr1	APN	15	85,815,546 (GRCm39)	missense	probably benign	0.04
IGL00519:Celsr1	APN	15	85,915,037 (GRCm39)	missense	probably damaging	1.00
IGL00909:Celsr1	APN	15	85,806,436 (GRCm39)	missense	probably damaging	1.00
IGL01303:Celsr1	APN	15	85,914,692 (GRCm39)	missense	probably damaging	0.97
IGL01726:Celsr1	APN	15	85,810,391 (GRCm39)	missense	probably benign	0.35
IGL01910:Celsr1	APN	15	85,814,096 (GRCm39)	missense	probably benign
IGL01931:Celsr1	APN	15	85,791,861 (GRCm39)	missense	probably damaging	1.00
IGL01952:Celsr1	APN	15	85,847,424 (GRCm39)	missense	probably benign	0.35
IGL02090:Celsr1	APN	15	85,791,922 (GRCm39)	missense	possibly damaging	0.49
IGL02191:Celsr1	APN	15	85,863,205 (GRCm39)	missense	possibly damaging	0.69
IGL02372:Celsr1	APN	15	85,814,108 (GRCm39)	missense	probably benign	0.01
IGL02413:Celsr1	APN	15	85,915,427 (GRCm39)	missense	possibly damaging	0.96
IGL02478:Celsr1	APN	15	85,825,337 (GRCm39)	missense	possibly damaging	0.68
IGL02507:Celsr1	APN	15	85,784,889 (GRCm39)	utr 3 prime	probably benign
IGL02508:Celsr1	APN	15	85,914,818 (GRCm39)	nonsense	probably null
IGL02899:Celsr1	APN	15	85,915,927 (GRCm39)	missense	probably damaging	0.98
IGL02939:Celsr1	APN	15	85,785,673 (GRCm39)	missense	probably benign
IGL03212:Celsr1	APN	15	85,814,878 (GRCm39)	missense	probably benign	0.04
P0028:Celsr1	UTSW	15	85,806,436 (GRCm39)	missense	probably damaging	1.00
PIT4305001:Celsr1	UTSW	15	85,785,138 (GRCm39)	missense	possibly damaging	0.87
PIT4480001:Celsr1	UTSW	15	85,916,615 (GRCm39)	missense	probably damaging	0.99
R0018:Celsr1	UTSW	15	85,915,243 (GRCm39)	missense	possibly damaging	0.47
R0018:Celsr1	UTSW	15	85,915,243 (GRCm39)	missense	possibly damaging	0.47
R0038:Celsr1	UTSW	15	85,813,620 (GRCm39)	missense	possibly damaging	0.65
R0057:Celsr1	UTSW	15	85,914,963 (GRCm39)	missense	probably benign	0.02
R0060:Celsr1	UTSW	15	85,806,399 (GRCm39)	missense	probably damaging	0.98
R0060:Celsr1	UTSW	15	85,806,399 (GRCm39)	missense	probably damaging	0.98
R0279:Celsr1	UTSW	15	85,787,065 (GRCm39)	missense	probably benign	0.00
R0570:Celsr1	UTSW	15	85,787,566 (GRCm39)	missense	probably benign	0.18
R0611:Celsr1	UTSW	15	85,816,524 (GRCm39)	missense	possibly damaging	0.91
R0731:Celsr1	UTSW	15	85,785,798 (GRCm39)	missense	probably benign
R0792:Celsr1	UTSW	15	85,815,477 (GRCm39)	missense	probably benign	0.02
R0943:Celsr1	UTSW	15	85,787,489 (GRCm39)	missense	probably damaging	1.00
R0989:Celsr1	UTSW	15	85,915,480 (GRCm39)	missense	probably benign	0.39
R1118:Celsr1	UTSW	15	85,916,248 (GRCm39)	missense	probably damaging	1.00
R1237:Celsr1	UTSW	15	85,788,175 (GRCm39)	missense	probably benign	0.01
R1239:Celsr1	UTSW	15	85,863,347 (GRCm39)	missense	probably damaging	0.99
R1405:Celsr1	UTSW	15	85,789,635 (GRCm39)	splice site	probably null
R1405:Celsr1	UTSW	15	85,789,635 (GRCm39)	splice site	probably null
R1522:Celsr1	UTSW	15	85,815,477 (GRCm39)	missense	probably benign	0.02
R1662:Celsr1	UTSW	15	85,915,263 (GRCm39)	missense	probably damaging	1.00
R1673:Celsr1	UTSW	15	85,816,658 (GRCm39)	missense	probably benign	0.00
R1795:Celsr1	UTSW	15	85,914,524 (GRCm39)	missense	probably damaging	0.99
R1799:Celsr1	UTSW	15	85,916,886 (GRCm39)	missense	probably damaging	1.00
R1858:Celsr1	UTSW	15	85,916,960 (GRCm39)	missense	probably damaging	1.00
R2040:Celsr1	UTSW	15	85,917,088 (GRCm39)	missense	probably damaging	1.00
R2050:Celsr1	UTSW	15	85,914,748 (GRCm39)	missense	probably benign	0.02
R2131:Celsr1	UTSW	15	85,847,424 (GRCm39)	missense	probably benign	0.35
R2132:Celsr1	UTSW	15	85,916,168 (GRCm39)	missense	possibly damaging	0.91
R2189:Celsr1	UTSW	15	85,863,431 (GRCm39)	missense	possibly damaging	0.93
R2192:Celsr1	UTSW	15	85,800,924 (GRCm39)	missense	possibly damaging	0.93
R4213:Celsr1	UTSW	15	85,916,008 (GRCm39)	missense	probably damaging	1.00
R4356:Celsr1	UTSW	15	85,863,028 (GRCm39)	missense	probably damaging	1.00
R4414:Celsr1	UTSW	15	85,812,200 (GRCm39)	missense	probably damaging	1.00
R4414:Celsr1	UTSW	15	85,847,334 (GRCm39)	missense	probably benign	0.00
R4416:Celsr1	UTSW	15	85,812,200 (GRCm39)	missense	probably damaging	1.00
R4645:Celsr1	UTSW	15	85,800,957 (GRCm39)	missense	probably benign	0.35
R4666:Celsr1	UTSW	15	85,914,695 (GRCm39)	missense	probably damaging	1.00
R4687:Celsr1	UTSW	15	85,816,661 (GRCm39)	missense	possibly damaging	0.94
R4735:Celsr1	UTSW	15	85,790,230 (GRCm39)	critical splice acceptor site	probably null
R4804:Celsr1	UTSW	15	85,822,154 (GRCm39)	missense	possibly damaging	0.49
R4995:Celsr1	UTSW	15	85,822,112 (GRCm39)	missense	probably damaging	0.99
R5070:Celsr1	UTSW	15	85,823,335 (GRCm39)	missense	possibly damaging	0.89
R5218:Celsr1	UTSW	15	85,816,585 (GRCm39)	missense	probably damaging	1.00
R5280:Celsr1	UTSW	15	85,814,747 (GRCm39)	missense	probably benign
R5310:Celsr1	UTSW	15	85,810,423 (GRCm39)	missense	possibly damaging	0.88
R5388:Celsr1	UTSW	15	85,809,719 (GRCm39)	missense	probably damaging	0.99
R5484:Celsr1	UTSW	15	85,815,483 (GRCm39)	missense	probably benign	0.00
R5639:Celsr1	UTSW	15	85,914,968 (GRCm39)	missense	probably damaging	1.00
R5758:Celsr1	UTSW	15	85,825,465 (GRCm39)	missense	probably benign	0.27
R5778:Celsr1	UTSW	15	85,917,156 (GRCm39)	missense	probably damaging	1.00
R5893:Celsr1	UTSW	15	85,788,215 (GRCm39)	missense	probably benign	0.02
R5915:Celsr1	UTSW	15	85,914,550 (GRCm39)	missense	probably damaging	0.96
R5915:Celsr1	UTSW	15	85,822,176 (GRCm39)	missense	probably benign
R5932:Celsr1	UTSW	15	85,916,905 (GRCm39)	missense	probably damaging	1.00
R5950:Celsr1	UTSW	15	85,916,701 (GRCm39)	missense	probably damaging	1.00
R5975:Celsr1	UTSW	15	85,803,239 (GRCm39)	splice site	probably null
R6050:Celsr1	UTSW	15	85,814,812 (GRCm39)	missense	probably benign	0.00
R6117:Celsr1	UTSW	15	85,816,612 (GRCm39)	missense	probably benign	0.04
R6178:Celsr1	UTSW	15	85,785,222 (GRCm39)	missense	probably benign	0.08
R6186:Celsr1	UTSW	15	85,805,394 (GRCm39)	missense	possibly damaging	0.84
R6212:Celsr1	UTSW	15	85,800,888 (GRCm39)	missense	probably benign	0.25
R6307:Celsr1	UTSW	15	85,812,531 (GRCm39)	missense	probably benign
R6320:Celsr1	UTSW	15	85,785,160 (GRCm39)	missense	probably benign	0.13
R6349:Celsr1	UTSW	15	85,915,885 (GRCm39)	missense	probably damaging	1.00
R6478:Celsr1	UTSW	15	85,809,719 (GRCm39)	missense	probably damaging	0.99
R6504:Celsr1	UTSW	15	85,863,121 (GRCm39)	missense	probably benign	0.07
R6607:Celsr1	UTSW	15	85,847,486 (GRCm39)	missense	probably benign
R6615:Celsr1	UTSW	15	85,786,315 (GRCm39)	critical splice donor site	probably null
R6661:Celsr1	UTSW	15	85,803,135 (GRCm39)	missense	probably damaging	1.00
R6722:Celsr1	UTSW	15	85,790,115 (GRCm39)	critical splice donor site	probably null
R6743:Celsr1	UTSW	15	85,791,799 (GRCm39)	missense	probably damaging	0.96
R6746:Celsr1	UTSW	15	85,915,696 (GRCm39)	missense	probably damaging	1.00
R6772:Celsr1	UTSW	15	85,914,983 (GRCm39)	missense	probably benign
R6838:Celsr1	UTSW	15	85,823,395 (GRCm39)	missense	probably benign
R6886:Celsr1	UTSW	15	85,915,855 (GRCm39)	missense	probably benign	0.00
R7030:Celsr1	UTSW	15	85,789,679 (GRCm39)	missense	probably damaging	0.99
R7060:Celsr1	UTSW	15	85,916,856 (GRCm39)	missense	probably benign	0.07
R7080:Celsr1	UTSW	15	85,816,652 (GRCm39)	missense	possibly damaging	0.87
R7325:Celsr1	UTSW	15	85,917,209 (GRCm39)	missense	probably damaging	0.99
R7357:Celsr1	UTSW	15	85,914,715 (GRCm39)	missense	probably benign	0.00
R7371:Celsr1	UTSW	15	85,914,875 (GRCm39)	missense	possibly damaging	0.91
R7446:Celsr1	UTSW	15	85,791,874 (GRCm39)	missense	possibly damaging	0.95
R7465:Celsr1	UTSW	15	85,917,593 (GRCm39)	missense	probably benign
R7491:Celsr1	UTSW	15	85,916,719 (GRCm39)	missense	possibly damaging	0.78
R7639:Celsr1	UTSW	15	85,814,073 (GRCm39)	missense	probably benign	0.00
R7685:Celsr1	UTSW	15	85,862,933 (GRCm39)	nonsense	probably null
R7741:Celsr1	UTSW	15	85,863,303 (GRCm39)	missense	possibly damaging	0.94
R7974:Celsr1	UTSW	15	85,915,231 (GRCm39)	missense	probably damaging	1.00
R7977:Celsr1	UTSW	15	85,917,194 (GRCm39)	missense	probably damaging	1.00
R7987:Celsr1	UTSW	15	85,917,194 (GRCm39)	missense	probably damaging	1.00
R8073:Celsr1	UTSW	15	85,823,356 (GRCm39)	missense	probably benign	0.00
R8099:Celsr1	UTSW	15	85,915,801 (GRCm39)	missense	probably damaging	0.99
R8190:Celsr1	UTSW	15	85,787,090 (GRCm39)	missense	probably damaging	0.99
R8210:Celsr1	UTSW	15	85,863,436 (GRCm39)	missense	probably benign	0.00
R8289:Celsr1	UTSW	15	85,917,286 (GRCm39)	nonsense	probably null
R8290:Celsr1	UTSW	15	85,917,286 (GRCm39)	nonsense	probably null
R8292:Celsr1	UTSW	15	85,791,819 (GRCm39)	missense	possibly damaging	0.90
R8328:Celsr1	UTSW	15	85,806,445 (GRCm39)	missense	probably benign	0.00
R8330:Celsr1	UTSW	15	85,816,501 (GRCm39)	missense	probably damaging	0.99
R8333:Celsr1	UTSW	15	85,915,615 (GRCm39)	missense	possibly damaging	0.65
R8352:Celsr1	UTSW	15	85,917,286 (GRCm39)	nonsense	probably null
R8384:Celsr1	UTSW	15	85,917,286 (GRCm39)	nonsense	probably null
R8452:Celsr1	UTSW	15	85,917,286 (GRCm39)	nonsense	probably null
R8463:Celsr1	UTSW	15	85,914,415 (GRCm39)	missense	probably damaging	1.00
R8479:Celsr1	UTSW	15	85,917,286 (GRCm39)	nonsense	probably null
R8480:Celsr1	UTSW	15	85,917,286 (GRCm39)	nonsense	probably null
R8493:Celsr1	UTSW	15	85,822,207 (GRCm39)	missense	possibly damaging	0.67
R8498:Celsr1	UTSW	15	85,823,306 (GRCm39)	missense	probably benign	0.01
R8506:Celsr1	UTSW	15	85,917,286 (GRCm39)	nonsense	probably null
R8771:Celsr1	UTSW	15	85,788,175 (GRCm39)	missense	probably benign	0.01
R8891:Celsr1	UTSW	15	85,822,194 (GRCm39)	missense	probably benign	0.01
R8905:Celsr1	UTSW	15	85,788,269 (GRCm39)	intron	probably benign
R8924:Celsr1	UTSW	15	85,916,671 (GRCm39)	missense	possibly damaging	0.94
R8979:Celsr1	UTSW	15	85,847,340 (GRCm39)	missense	probably damaging	0.96
R9069:Celsr1	UTSW	15	85,914,772 (GRCm39)	missense	possibly damaging	0.53
R9115:Celsr1	UTSW	15	85,803,217 (GRCm39)	missense	probably damaging	1.00
R9194:Celsr1	UTSW	15	85,917,286 (GRCm39)	nonsense	probably null
R9196:Celsr1	UTSW	15	85,917,286 (GRCm39)	nonsense	probably null
R9198:Celsr1	UTSW	15	85,917,286 (GRCm39)	nonsense	probably null
R9200:Celsr1	UTSW	15	85,917,286 (GRCm39)	nonsense	probably null
R9201:Celsr1	UTSW	15	85,917,286 (GRCm39)	nonsense	probably null
R9202:Celsr1	UTSW	15	85,917,286 (GRCm39)	nonsense	probably null
R9203:Celsr1	UTSW	15	85,917,286 (GRCm39)	nonsense	probably null
R9222:Celsr1	UTSW	15	85,815,471 (GRCm39)	missense	possibly damaging	0.68
R9236:Celsr1	UTSW	15	85,915,051 (GRCm39)	missense	probably damaging	1.00
R9384:Celsr1	UTSW	15	85,917,286 (GRCm39)	nonsense	probably null
R9386:Celsr1	UTSW	15	85,863,231 (GRCm39)	missense	probably damaging	1.00
R9400:Celsr1	UTSW	15	85,917,286 (GRCm39)	nonsense	probably null
R9401:Celsr1	UTSW	15	85,917,286 (GRCm39)	nonsense	probably null
R9415:Celsr1	UTSW	15	85,917,286 (GRCm39)	nonsense	probably null
R9428:Celsr1	UTSW	15	85,815,549 (GRCm39)	missense	possibly damaging	0.64
R9435:Celsr1	UTSW	15	85,806,535 (GRCm39)	splice site	probably benign
R9493:Celsr1	UTSW	15	85,785,346 (GRCm39)	missense	probably damaging	0.98
R9495:Celsr1	UTSW	15	85,917,286 (GRCm39)	nonsense	probably null
R9499:Celsr1	UTSW	15	85,917,286 (GRCm39)	nonsense	probably null
R9607:Celsr1	UTSW	15	85,915,229 (GRCm39)	missense
R9673:Celsr1	UTSW	15	85,917,286 (GRCm39)	nonsense	probably null
Z1176:Celsr1	UTSW	15	85,847,301 (GRCm39)	missense	probably damaging	0.96
Z1177:Celsr1	UTSW	15	85,863,052 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- TATGTTGACCAAACCCACAAGG -3'
(R):5'- TGTAATTGTCTGCAGGCCG -3'

Sequencing Primer
(F):5'- ACAAGGTCCCTGTAGGTCC -3'
(R):5'- GTTTTCCATGTCACCGTAACTGTAG -3'

Posted On

2019-11-26