Incidental Mutation 'R7779:Atp8b1'
| ID |
599124 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Atp8b1
|
| Ensembl Gene |
ENSMUSG00000039529 |
| Gene Name |
ATPase, class I, type 8B, member 1 |
| Synonyms |
Ic, FIC1 |
| MMRRC Submission |
045835-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7779 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
18 |
| Chromosomal Location |
64662050-64794342 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 64674453 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Proline
at position 943
(S943P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000025482
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000025482]
|
| AlphaFold |
Q148W0 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000025482
AA Change: S943P
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000025482
Gene: ENSMUSG00000039529
AA Change: S943P
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:PhoLip_ATPase_N
|
65 |
144 |
5.3e-29 |
PFAM |
|
Pfam:E1-E2_ATPase
|
146 |
413 |
6e-11 |
PFAM |
|
Pfam:HAD
|
451 |
902 |
2.4e-21 |
PFAM |
|
Pfam:Cation_ATPase
|
532 |
632 |
1e-12 |
PFAM |
|
Pfam:PhoLip_ATPase_C
|
919 |
1173 |
7.3e-82 |
PFAM |
|
low complexity region
|
1193 |
1207 |
N/A |
INTRINSIC |
|
low complexity region
|
1221 |
1232 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.7%
- 20x: 99.2%
|
| Validation Efficiency |
98% (92/94) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the P-type cation transport ATPase family, which belongs to the subfamily of aminophospholipid-transporting ATPases. The aminophospholipid translocases transport phosphatidylserine and phosphatidylethanolamine from one side of a bilayer to another. Mutations in this gene may result in progressive familial intrahepatic cholestasis type 1 and in benign recurrent intrahepatic cholestasis. [provided by RefSeq, Jul 2008]
PHENOTYPE: Homozygous mice display abnormal bile salt homeostasis, normal bile secretion, and an impaired ability to handle increased bile salt loading resulting in liver damage and weight loss on a bile salt supplemented diet. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 93 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 9330159F19Rik |
T |
A |
10: 29,101,316 (GRCm39) |
V563E |
probably damaging |
Het |
| Adra1d |
A |
G |
2: 131,403,805 (GRCm39) |
V95A |
probably damaging |
Het |
| Ak7 |
A |
C |
12: 105,708,609 (GRCm39) |
I355L |
probably benign |
Het |
| Ank1 |
G |
A |
8: 23,586,763 (GRCm39) |
|
probably null |
Het |
| Apol7c |
A |
T |
15: 77,409,946 (GRCm39) |
H333Q |
probably damaging |
Het |
| Arfgef3 |
T |
C |
10: 18,470,771 (GRCm39) |
M1665V |
probably damaging |
Het |
| Arid5b |
A |
G |
10: 67,932,606 (GRCm39) |
Y1099H |
probably damaging |
Het |
| BC005537 |
C |
T |
13: 24,987,382 (GRCm39) |
R7W |
possibly damaging |
Het |
| Bcl2l2 |
C |
T |
14: 55,121,836 (GRCm39) |
|
probably benign |
Het |
| Bco1 |
A |
G |
8: 117,844,135 (GRCm39) |
Y283C |
probably damaging |
Het |
| Brd4 |
A |
T |
17: 32,431,910 (GRCm39) |
D652E |
probably benign |
Het |
| Cacna1s |
G |
A |
1: 136,046,767 (GRCm39) |
A1799T |
probably damaging |
Het |
| Camsap3 |
A |
G |
8: 3,647,887 (GRCm39) |
Y65C |
probably damaging |
Het |
| Capn1 |
T |
C |
19: 6,044,116 (GRCm39) |
K535E |
probably benign |
Het |
| Cbl |
A |
G |
9: 44,070,393 (GRCm39) |
S480P |
probably benign |
Het |
| Cfap99 |
A |
C |
5: 34,469,008 (GRCm39) |
N294T |
probably benign |
Het |
| Defa24 |
A |
C |
8: 22,225,355 (GRCm39) |
S82R |
probably benign |
Het |
| Dnai2 |
T |
C |
11: 114,645,235 (GRCm39) |
F557L |
possibly damaging |
Het |
| Dnhd1 |
T |
A |
7: 105,327,122 (GRCm39) |
H690Q |
probably benign |
Het |
| Dock2 |
A |
G |
11: 34,605,282 (GRCm39) |
V279A |
probably benign |
Het |
| Dst |
T |
A |
1: 34,233,678 (GRCm39) |
V3462E |
probably damaging |
Het |
| E2f3 |
T |
G |
13: 30,102,598 (GRCm39) |
H221P |
probably damaging |
Het |
| Eif2b4 |
A |
T |
5: 31,347,998 (GRCm39) |
I238N |
probably damaging |
Het |
| Eno4 |
T |
C |
19: 58,956,975 (GRCm39) |
S530P |
probably benign |
Het |
| Epb42 |
T |
G |
2: 120,864,916 (GRCm39) |
K58N |
probably benign |
Het |
| Etl4 |
C |
T |
2: 20,714,288 (GRCm39) |
T129I |
probably damaging |
Het |
| Extl1 |
A |
G |
4: 134,085,014 (GRCm39) |
F652S |
probably damaging |
Het |
| Extl1 |
T |
C |
4: 134,087,908 (GRCm39) |
K449E |
probably benign |
Het |
| F13b |
T |
A |
1: 139,444,124 (GRCm39) |
V486E |
probably benign |
Het |
| Fbln2 |
T |
A |
6: 91,210,176 (GRCm39) |
L40Q |
probably damaging |
Het |
| Glp2r |
C |
T |
11: 67,600,609 (GRCm39) |
W413* |
probably null |
Het |
| Grin2b |
A |
T |
6: 135,755,792 (GRCm39) |
Y507* |
probably null |
Het |
| H2-M11 |
G |
T |
17: 36,859,698 (GRCm39) |
L230F |
probably benign |
Het |
| Il36a |
T |
C |
2: 24,106,613 (GRCm39) |
Y66H |
probably damaging |
Het |
| Itpr1 |
A |
G |
6: 108,500,309 (GRCm39) |
E2634G |
possibly damaging |
Het |
| Itpr3 |
A |
T |
17: 27,315,037 (GRCm39) |
Y728F |
probably damaging |
Het |
| Jak1 |
C |
T |
4: 101,017,339 (GRCm39) |
E764K |
probably benign |
Het |
| Jak3 |
G |
T |
8: 72,139,932 (GRCm39) |
R1045L |
probably benign |
Het |
| Jam2 |
T |
C |
16: 84,606,271 (GRCm39) |
I95T |
probably damaging |
Het |
| Kdf1 |
T |
C |
4: 133,255,796 (GRCm39) |
V171A |
probably damaging |
Het |
| Lactbl1 |
A |
T |
4: 136,358,307 (GRCm39) |
K93* |
probably null |
Het |
| Lcn6 |
T |
C |
2: 25,570,805 (GRCm39) |
V131A |
probably benign |
Het |
| Lpar5 |
T |
A |
6: 125,059,207 (GRCm39) |
D309E |
probably damaging |
Het |
| Lrfn4 |
T |
C |
19: 4,663,715 (GRCm39) |
E273G |
probably damaging |
Het |
| Lta4h |
C |
T |
10: 93,310,811 (GRCm39) |
T447I |
probably benign |
Het |
| Lyst |
A |
G |
13: 13,809,128 (GRCm39) |
E266G |
probably damaging |
Het |
| Mab21l1 |
A |
T |
3: 55,690,796 (GRCm39) |
I128F |
possibly damaging |
Het |
| Mrgprb4 |
T |
G |
7: 47,848,895 (GRCm39) |
N11T |
probably benign |
Het |
| Mroh6 |
G |
A |
15: 75,760,505 (GRCm39) |
T23I |
possibly damaging |
Het |
| Myo1f |
T |
C |
17: 33,797,247 (GRCm39) |
I143T |
probably benign |
Het |
| Myof |
C |
T |
19: 37,927,838 (GRCm39) |
D1092N |
probably damaging |
Het |
| Ncan |
G |
T |
8: 70,567,661 (GRCm39) |
D150E |
probably damaging |
Het |
| Or1d2 |
T |
A |
11: 74,255,771 (GRCm39) |
I92N |
probably damaging |
Het |
| Or2y1f |
T |
A |
11: 49,185,048 (GRCm39) |
L300Q |
probably damaging |
Het |
| Or6c88 |
A |
T |
10: 129,407,180 (GRCm39) |
I219F |
probably damaging |
Het |
| Pcm1 |
A |
G |
8: 41,782,061 (GRCm39) |
Y1948C |
probably damaging |
Het |
| Pcsk6 |
A |
T |
7: 65,675,152 (GRCm39) |
T669S |
probably benign |
Het |
| Pdlim5 |
A |
C |
3: 141,948,447 (GRCm39) |
N613K |
probably benign |
Het |
| Pdzk1 |
T |
A |
3: 96,764,589 (GRCm39) |
V291D |
probably damaging |
Het |
| Plbd2 |
T |
C |
5: 120,625,743 (GRCm39) |
Q408R |
probably damaging |
Het |
| Ppp1r37 |
C |
A |
7: 19,266,712 (GRCm39) |
A392S |
possibly damaging |
Het |
| Proser2 |
T |
A |
2: 6,107,878 (GRCm39) |
|
probably null |
Het |
| Psmd12 |
T |
C |
11: 107,388,405 (GRCm39) |
V406A |
probably benign |
Het |
| Rab3gap2 |
T |
C |
1: 184,991,641 (GRCm39) |
V709A |
probably damaging |
Het |
| Radil |
T |
C |
5: 142,473,320 (GRCm39) |
E787G |
probably benign |
Het |
| Rai14 |
A |
C |
15: 10,593,112 (GRCm39) |
D177E |
probably damaging |
Het |
| Rbms2 |
G |
A |
10: 127,979,315 (GRCm39) |
T166I |
probably damaging |
Het |
| Rrh |
C |
T |
3: 129,608,969 (GRCm39) |
C115Y |
probably benign |
Het |
| Slc1a6 |
C |
T |
10: 78,631,789 (GRCm39) |
T205I |
probably damaging |
Het |
| Sost |
T |
C |
11: 101,857,675 (GRCm39) |
E42G |
possibly damaging |
Het |
| Spcs3 |
T |
A |
8: 54,982,805 (GRCm39) |
I46F |
possibly damaging |
Het |
| Spg11 |
A |
G |
2: 121,901,420 (GRCm39) |
S1507P |
probably damaging |
Het |
| Sprtn |
C |
T |
8: 125,624,982 (GRCm39) |
P29L |
possibly damaging |
Het |
| Sptan1 |
C |
T |
2: 29,911,319 (GRCm39) |
T1886I |
probably damaging |
Het |
| Strn4 |
T |
C |
7: 16,565,417 (GRCm39) |
F394S |
probably damaging |
Het |
| Syt14 |
A |
T |
1: 192,666,751 (GRCm39) |
M51K |
unknown |
Het |
| Terb2 |
A |
G |
2: 122,016,975 (GRCm39) |
K32R |
probably benign |
Het |
| Tex15 |
G |
A |
8: 34,065,309 (GRCm39) |
G1580R |
probably damaging |
Het |
| Thumpd3 |
T |
C |
6: 113,036,950 (GRCm39) |
V283A |
probably damaging |
Het |
| Tm7sf2 |
T |
C |
19: 6,112,947 (GRCm39) |
Y418C |
possibly damaging |
Het |
| Trim24 |
T |
G |
6: 37,896,332 (GRCm39) |
F263C |
probably damaging |
Het |
| Trim24 |
T |
A |
6: 37,896,333 (GRCm39) |
F263L |
probably damaging |
Het |
| Trip11 |
A |
G |
12: 101,849,796 (GRCm39) |
S1423P |
probably damaging |
Het |
| Vps13c |
G |
A |
9: 67,788,704 (GRCm39) |
V326M |
probably damaging |
Het |
| Vps37c |
T |
C |
19: 10,689,988 (GRCm39) |
V150A |
probably damaging |
Het |
| Wdr90 |
C |
T |
17: 26,065,300 (GRCm39) |
R1652Q |
probably damaging |
Het |
| Wfdc9 |
A |
G |
2: 164,492,516 (GRCm39) |
V37A |
probably damaging |
Het |
| Yif1b |
T |
A |
7: 28,945,328 (GRCm39) |
M227K |
probably damaging |
Het |
| Zbtb18 |
T |
C |
1: 177,274,505 (GRCm39) |
|
probably benign |
Het |
| Zfp318 |
A |
G |
17: 46,710,820 (GRCm39) |
T848A |
probably benign |
Het |
| Zfp808 |
T |
A |
13: 62,320,571 (GRCm39) |
I600K |
possibly damaging |
Het |
| Zmym1 |
C |
A |
4: 126,948,038 (GRCm39) |
S111I |
probably benign |
Het |
| Zmym2 |
A |
G |
14: 57,165,740 (GRCm39) |
T688A |
probably damaging |
Het |
|
| Other mutations in Atp8b1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00472:Atp8b1
|
APN |
18 |
64,697,501 (GRCm39) |
missense |
probably benign |
0.23 |
|
IGL00907:Atp8b1
|
APN |
18 |
64,694,776 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL00962:Atp8b1
|
APN |
18 |
64,664,515 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01433:Atp8b1
|
APN |
18 |
64,706,590 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01525:Atp8b1
|
APN |
18 |
64,672,323 (GRCm39) |
nonsense |
probably null |
|
|
IGL01645:Atp8b1
|
APN |
18 |
64,679,184 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL02008:Atp8b1
|
APN |
18 |
64,671,766 (GRCm39) |
splice site |
probably benign |
|
|
IGL02227:Atp8b1
|
APN |
18 |
64,695,261 (GRCm39) |
missense |
probably benign |
|
|
IGL02231:Atp8b1
|
APN |
18 |
64,683,455 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL02326:Atp8b1
|
APN |
18 |
64,671,654 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02562:Atp8b1
|
APN |
18 |
64,715,057 (GRCm39) |
missense |
probably benign |
|
|
IGL02929:Atp8b1
|
APN |
18 |
64,694,733 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
enchilada
|
UTSW |
18 |
64,679,060 (GRCm39) |
critical splice donor site |
probably null |
|
|
PIT4520001:Atp8b1
|
UTSW |
18 |
64,701,251 (GRCm39) |
missense |
probably benign |
0.34 |
|
PIT4696001:Atp8b1
|
UTSW |
18 |
64,672,341 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0144:Atp8b1
|
UTSW |
18 |
64,704,445 (GRCm39) |
splice site |
probably benign |
|
|
R0193:Atp8b1
|
UTSW |
18 |
64,694,707 (GRCm39) |
missense |
probably benign |
|
|
R0277:Atp8b1
|
UTSW |
18 |
64,701,323 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0308:Atp8b1
|
UTSW |
18 |
64,678,315 (GRCm39) |
nonsense |
probably null |
|
|
R0323:Atp8b1
|
UTSW |
18 |
64,701,323 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0403:Atp8b1
|
UTSW |
18 |
64,673,381 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0601:Atp8b1
|
UTSW |
18 |
64,704,724 (GRCm39) |
splice site |
probably null |
|
|
R0614:Atp8b1
|
UTSW |
18 |
64,666,658 (GRCm39) |
splice site |
probably benign |
|
|
R0883:Atp8b1
|
UTSW |
18 |
64,697,612 (GRCm39) |
missense |
probably benign |
0.44 |
|
R1077:Atp8b1
|
UTSW |
18 |
64,706,333 (GRCm39) |
nonsense |
probably null |
|
|
R1292:Atp8b1
|
UTSW |
18 |
64,704,092 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1494:Atp8b1
|
UTSW |
18 |
64,697,597 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1522:Atp8b1
|
UTSW |
18 |
64,683,503 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1534:Atp8b1
|
UTSW |
18 |
64,678,335 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1535:Atp8b1
|
UTSW |
18 |
64,678,335 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1536:Atp8b1
|
UTSW |
18 |
64,678,335 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1537:Atp8b1
|
UTSW |
18 |
64,678,335 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1650:Atp8b1
|
UTSW |
18 |
64,704,620 (GRCm39) |
splice site |
probably benign |
|
|
R1772:Atp8b1
|
UTSW |
18 |
64,706,563 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R2016:Atp8b1
|
UTSW |
18 |
64,673,405 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2017:Atp8b1
|
UTSW |
18 |
64,673,405 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2043:Atp8b1
|
UTSW |
18 |
64,738,271 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R2223:Atp8b1
|
UTSW |
18 |
64,697,428 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R3052:Atp8b1
|
UTSW |
18 |
64,686,179 (GRCm39) |
missense |
probably benign |
0.04 |
|
R3694:Atp8b1
|
UTSW |
18 |
64,666,792 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R3738:Atp8b1
|
UTSW |
18 |
64,666,800 (GRCm39) |
splice site |
probably benign |
|
|
R4211:Atp8b1
|
UTSW |
18 |
64,686,118 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4362:Atp8b1
|
UTSW |
18 |
64,697,608 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4560:Atp8b1
|
UTSW |
18 |
64,701,318 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4560:Atp8b1
|
UTSW |
18 |
64,689,950 (GRCm39) |
nonsense |
probably null |
|
|
R4562:Atp8b1
|
UTSW |
18 |
64,689,962 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4615:Atp8b1
|
UTSW |
18 |
64,686,170 (GRCm39) |
missense |
probably null |
|
|
R4676:Atp8b1
|
UTSW |
18 |
64,671,749 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4738:Atp8b1
|
UTSW |
18 |
64,678,251 (GRCm39) |
missense |
probably benign |
0.31 |
|
R4774:Atp8b1
|
UTSW |
18 |
64,666,730 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R4808:Atp8b1
|
UTSW |
18 |
64,694,782 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4868:Atp8b1
|
UTSW |
18 |
64,684,937 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5162:Atp8b1
|
UTSW |
18 |
64,694,733 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R5289:Atp8b1
|
UTSW |
18 |
64,679,158 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R5328:Atp8b1
|
UTSW |
18 |
64,664,462 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5400:Atp8b1
|
UTSW |
18 |
64,679,060 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5587:Atp8b1
|
UTSW |
18 |
64,672,281 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5623:Atp8b1
|
UTSW |
18 |
64,679,165 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R5651:Atp8b1
|
UTSW |
18 |
64,664,453 (GRCm39) |
missense |
probably benign |
0.31 |
|
R5652:Atp8b1
|
UTSW |
18 |
64,664,453 (GRCm39) |
missense |
probably benign |
0.31 |
|
R5653:Atp8b1
|
UTSW |
18 |
64,678,268 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5667:Atp8b1
|
UTSW |
18 |
64,714,994 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5689:Atp8b1
|
UTSW |
18 |
64,697,608 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6008:Atp8b1
|
UTSW |
18 |
64,710,687 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6315:Atp8b1
|
UTSW |
18 |
64,664,550 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6759:Atp8b1
|
UTSW |
18 |
64,679,161 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6850:Atp8b1
|
UTSW |
18 |
64,689,923 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7255:Atp8b1
|
UTSW |
18 |
64,689,939 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7606:Atp8b1
|
UTSW |
18 |
64,688,186 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7635:Atp8b1
|
UTSW |
18 |
64,706,376 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R7639:Atp8b1
|
UTSW |
18 |
64,697,614 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R7698:Atp8b1
|
UTSW |
18 |
64,704,093 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7727:Atp8b1
|
UTSW |
18 |
64,678,346 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7785:Atp8b1
|
UTSW |
18 |
64,689,921 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7874:Atp8b1
|
UTSW |
18 |
64,704,095 (GRCm39) |
missense |
probably benign |
0.30 |
|
R7990:Atp8b1
|
UTSW |
18 |
64,671,748 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R8020:Atp8b1
|
UTSW |
18 |
64,679,084 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8161:Atp8b1
|
UTSW |
18 |
64,690,058 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9007:Atp8b1
|
UTSW |
18 |
64,684,931 (GRCm39) |
missense |
probably benign |
0.40 |
|
R9064:Atp8b1
|
UTSW |
18 |
64,697,491 (GRCm39) |
missense |
probably benign |
0.12 |
|
R9266:Atp8b1
|
UTSW |
18 |
64,710,528 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R9266:Atp8b1
|
UTSW |
18 |
64,704,108 (GRCm39) |
missense |
probably benign |
0.08 |
|
R9326:Atp8b1
|
UTSW |
18 |
64,706,344 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0025:Atp8b1
|
UTSW |
18 |
64,704,476 (GRCm39) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- CACTTTCAGACTTCCTTGTGAAATG -3'
(R):5'- GTGCCTTAAAAGTAATGTCTAACCCAC -3'
Sequencing Primer
(F):5'- TGAGGTCAATTCCTGAAGCC -3'
(R):5'- ATGTCTAACCCACTATTTCTTTTTCC -3'
|
| Posted On |
2019-11-26 |
Incidental Mutation