Incidental Mutation 'R7782:Dennd4a'
| ID |
599312 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dennd4a
|
| Ensembl Gene |
ENSMUSG00000053641 |
| Gene Name |
DENN/MADD domain containing 4A |
| Synonyms |
F730015K02Rik |
| MMRRC Submission |
045838-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.432)
|
| Stock # |
R7782 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
9 |
| Chromosomal Location |
64811340-64919667 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 64906920 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glycine
at position 1473
(D1473G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000037915
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000038890]
|
| AlphaFold |
E9Q8V6 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000038890
AA Change: D1473G
PolyPhen 2
Score 0.977 (Sensitivity: 0.76; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000037915
Gene: ENSMUSG00000053641
AA Change: D1473G
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_1
|
45 |
93 |
3.26e-5 |
PROSPERO |
|
uDENN
|
169 |
276 |
1.71e-28 |
SMART |
|
DENN
|
309 |
493 |
2.4e-73 |
SMART |
|
dDENN
|
559 |
633 |
4.15e-27 |
SMART |
|
low complexity region
|
724 |
735 |
N/A |
INTRINSIC |
|
low complexity region
|
936 |
950 |
N/A |
INTRINSIC |
|
low complexity region
|
1176 |
1191 |
N/A |
INTRINSIC |
|
low complexity region
|
1249 |
1262 |
N/A |
INTRINSIC |
|
low complexity region
|
1402 |
1417 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.4%
|
| Validation Efficiency |
100% (80/80) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a DENN domain-containing protein that may function as a guanine nucleotide exchange factor that specifically activates ras-related protein Rab-10. This protein also contains a interferon stimulated response element-binding domain and may be involved in regulating the v-myc avian myelocytomatosis viral (MYC) oncogene. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8. [provided by RefSeq, Mar 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 81 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4931409K22Rik |
A |
G |
5: 24,544,226 (GRCm38) |
L758P |
probably damaging |
Het |
| 4933415A04Rik |
GTGTGTGTATGTGTGT |
GTGTGTGT |
11: 43,587,412 (GRCm38) |
|
probably null |
Het |
| 5430419D17Rik |
G |
A |
7: 131,302,737 (GRCm38) |
|
probably null |
Het |
| Adamts16 |
A |
G |
13: 70,836,146 (GRCm38) |
S133P |
probably damaging |
Het |
| Adamts17 |
T |
C |
7: 67,125,054 (GRCm38) |
W1001R |
probably damaging |
Het |
| Aox4 |
T |
A |
1: 58,231,092 (GRCm38) |
|
probably null |
Het |
| B4galnt4 |
C |
T |
7: 141,065,075 (GRCm38) |
P221S |
probably damaging |
Het |
| BC005537 |
C |
T |
13: 24,803,399 (GRCm38) |
R7W |
possibly damaging |
Het |
| BC034090 |
T |
C |
1: 155,232,664 (GRCm38) |
|
probably benign |
Het |
| Best2 |
T |
A |
8: 85,009,514 (GRCm38) |
D312V |
probably damaging |
Het |
| Bod1l |
A |
T |
5: 41,817,943 (GRCm38) |
D2009E |
probably benign |
Het |
| Ccdc158 |
A |
C |
5: 92,645,514 (GRCm38) |
S672A |
probably benign |
Het |
| Ccdc43 |
A |
T |
11: 102,697,617 (GRCm38) |
L31Q |
probably damaging |
Het |
| Chaf1a |
T |
G |
17: 56,062,291 (GRCm38) |
H507Q |
probably benign |
Het |
| Clptm1l |
A |
G |
13: 73,604,320 (GRCm38) |
Y28C |
probably damaging |
Het |
| Cp |
G |
A |
3: 19,975,059 (GRCm38) |
|
probably null |
Het |
| Crocc |
C |
T |
4: 141,025,286 (GRCm38) |
A1432T |
probably benign |
Het |
| Crybg2 |
A |
G |
4: 134,073,826 (GRCm38) |
T457A |
probably benign |
Het |
| Diaph3 |
A |
G |
14: 87,037,504 (GRCm38) |
F172S |
probably benign |
Het |
| Dnajc5b |
A |
G |
3: 19,574,842 (GRCm38) |
N100S |
probably benign |
Het |
| Dusp13 |
G |
A |
14: 21,741,336 (GRCm38) |
T16I |
possibly damaging |
Het |
| Epb42 |
T |
G |
2: 121,034,435 (GRCm38) |
K58N |
probably benign |
Het |
| Fam208a |
A |
G |
14: 27,471,944 (GRCm38) |
T1034A |
probably benign |
Het |
| Fat1 |
A |
G |
8: 44,950,911 (GRCm38) |
Y233C |
probably damaging |
Het |
| Fcgbp |
T |
A |
7: 28,085,035 (GRCm38) |
Y173* |
probably null |
Het |
| Fign |
T |
A |
2: 63,979,162 (GRCm38) |
D588V |
probably damaging |
Het |
| Fignl2 |
C |
T |
15: 101,053,307 (GRCm38) |
V365M |
unknown |
Het |
| Fnip2 |
A |
C |
3: 79,508,123 (GRCm38) |
Y203D |
probably benign |
Het |
| Ftsj3 |
CCTTCTTCTTCTTCTTCT |
CCTTCTTCTTCTTCT |
11: 106,252,551 (GRCm38) |
|
probably benign |
Het |
| Gfral |
C |
A |
9: 76,193,290 (GRCm38) |
V289L |
probably benign |
Het |
| Gm10031 |
C |
T |
1: 156,524,982 (GRCm38) |
T251I |
probably damaging |
Het |
| Heatr5b |
G |
T |
17: 78,795,941 (GRCm38) |
T1161K |
probably damaging |
Het |
| Hectd4 |
A |
T |
5: 121,305,721 (GRCm38) |
I1335F |
possibly damaging |
Het |
| Hist2h2be |
T |
A |
3: 96,221,171 (GRCm38) |
|
probably null |
Het |
| Htt |
T |
A |
5: 34,882,992 (GRCm38) |
V2166D |
probably benign |
Het |
| Ipo5 |
G |
C |
14: 120,933,125 (GRCm38) |
K436N |
possibly damaging |
Het |
| Itga6 |
A |
G |
2: 71,841,535 (GRCm38) |
E794G |
probably damaging |
Het |
| Itga9 |
G |
A |
9: 118,843,644 (GRCm38) |
C148Y |
|
Het |
| Kcnip2 |
A |
C |
19: 45,797,085 (GRCm38) |
|
probably null |
Het |
| Kcnk6 |
T |
C |
7: 29,225,844 (GRCm38) |
T116A |
possibly damaging |
Het |
| Kctd21 |
A |
G |
7: 97,348,090 (GRCm38) |
I257V |
probably benign |
Het |
| Kif19a |
G |
A |
11: 114,781,922 (GRCm38) |
R299Q |
probably damaging |
Het |
| Kifc2 |
G |
A |
15: 76,664,128 (GRCm38) |
G391R |
probably benign |
Het |
| Klrg2 |
A |
G |
6: 38,627,627 (GRCm38) |
V381A |
possibly damaging |
Het |
| Mob1b |
A |
G |
5: 88,749,683 (GRCm38) |
|
probably null |
Het |
| Olfr1340 |
T |
C |
4: 118,726,909 (GRCm38) |
Y221H |
probably damaging |
Het |
| Olfr1356 |
T |
C |
10: 78,847,613 (GRCm38) |
I101V |
probably benign |
Het |
| Olfr790 |
T |
C |
10: 129,501,151 (GRCm38) |
V81A |
probably benign |
Het |
| Olfr816 |
T |
G |
10: 129,911,523 (GRCm38) |
S252R |
probably damaging |
Het |
| Oxsm |
C |
A |
14: 16,240,925 (GRCm38) |
A375S |
possibly damaging |
Het |
| Pcdha3 |
T |
C |
18: 36,948,140 (GRCm38) |
V645A |
probably damaging |
Het |
| Pcdhb15 |
T |
A |
18: 37,474,735 (GRCm38) |
V340E |
possibly damaging |
Het |
| Pced1a |
G |
A |
2: 130,422,515 (GRCm38) |
P132S |
probably damaging |
Het |
| Pla2r1 |
C |
T |
2: 60,504,187 (GRCm38) |
V414M |
probably benign |
Het |
| Plekhg4 |
A |
C |
8: 105,377,767 (GRCm38) |
I493L |
probably benign |
Het |
| Plekhj1 |
T |
A |
10: 80,798,345 (GRCm38) |
|
probably benign |
Het |
| Pmfbp1 |
G |
T |
8: 109,527,780 (GRCm38) |
K482N |
probably damaging |
Het |
| Ppil3 |
T |
C |
1: 58,434,415 (GRCm38) |
N92S |
probably benign |
Het |
| Ppt2 |
A |
G |
17: 34,625,712 (GRCm38) |
S156P |
probably benign |
Het |
| Prss41 |
A |
T |
17: 23,837,113 (GRCm38) |
D255E |
probably benign |
Het |
| Psg25 |
T |
A |
7: 18,521,302 (GRCm38) |
M430L |
probably benign |
Het |
| Rffl |
A |
T |
11: 82,812,769 (GRCm38) |
C109* |
probably null |
Het |
| Rock2 |
A |
G |
12: 16,971,110 (GRCm38) |
E991G |
probably benign |
Het |
| Rpap2 |
A |
G |
5: 107,620,192 (GRCm38) |
I299V |
probably benign |
Het |
| Rras |
T |
C |
7: 45,021,105 (GRCm38) |
S158P |
probably benign |
Het |
| Serpinb10 |
G |
A |
1: 107,535,466 (GRCm38) |
|
probably benign |
Het |
| Smyd3 |
A |
T |
1: 178,972,294 (GRCm38) |
I360N |
possibly damaging |
Het |
| Synm |
A |
G |
7: 67,734,966 (GRCm38) |
S541P |
probably damaging |
Het |
| Tbc1d31 |
C |
A |
15: 57,958,368 (GRCm38) |
T813K |
possibly damaging |
Het |
| Trav7n-4 |
A |
G |
14: 53,091,646 (GRCm38) |
M38V |
probably benign |
Het |
| Tulp3 |
A |
C |
6: 128,324,980 (GRCm38) |
N359K |
possibly damaging |
Het |
| Twf1 |
T |
C |
15: 94,582,773 (GRCm38) |
K196E |
probably benign |
Het |
| Usp24 |
A |
T |
4: 106,316,574 (GRCm38) |
N35Y |
probably damaging |
Het |
| Usp46 |
T |
A |
5: 74,002,111 (GRCm38) |
E342D |
probably benign |
Het |
| Vps50 |
T |
A |
6: 3,532,202 (GRCm38) |
|
probably null |
Het |
| Vps8 |
T |
A |
16: 21,511,558 (GRCm38) |
I727N |
possibly damaging |
Het |
| Wdr90 |
C |
T |
17: 25,846,326 (GRCm38) |
R1652Q |
probably damaging |
Het |
| Zfp11 |
A |
T |
5: 129,656,963 (GRCm38) |
V478E |
possibly damaging |
Het |
| Zfp493 |
A |
G |
13: 67,787,004 (GRCm38) |
K359E |
probably benign |
Het |
| Zfp536 |
T |
C |
7: 37,568,701 (GRCm38) |
Y430C |
probably damaging |
Het |
| Zfpm1 |
A |
G |
8: 122,336,950 (GRCm38) |
D916G |
unknown |
Het |
|
| Other mutations in Dennd4a |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00476:Dennd4a
|
APN |
9 |
64,911,762 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01610:Dennd4a
|
APN |
9 |
64,906,884 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL01788:Dennd4a
|
APN |
9 |
64,842,621 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL01827:Dennd4a
|
APN |
9 |
64,842,561 (GRCm38) |
nonsense |
probably null |
|
|
IGL01828:Dennd4a
|
APN |
9 |
64,842,561 (GRCm38) |
nonsense |
probably null |
|
|
IGL01829:Dennd4a
|
APN |
9 |
64,842,561 (GRCm38) |
nonsense |
probably null |
|
|
IGL01979:Dennd4a
|
APN |
9 |
64,894,409 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL02100:Dennd4a
|
APN |
9 |
64,909,706 (GRCm38) |
splice site |
probably benign |
|
|
IGL02339:Dennd4a
|
APN |
9 |
64,842,561 (GRCm38) |
nonsense |
probably null |
|
|
IGL02341:Dennd4a
|
APN |
9 |
64,842,561 (GRCm38) |
nonsense |
probably null |
|
|
IGL02584:Dennd4a
|
APN |
9 |
64,851,298 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02607:Dennd4a
|
APN |
9 |
64,862,327 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL02654:Dennd4a
|
APN |
9 |
64,910,191 (GRCm38) |
splice site |
probably benign |
|
|
IGL02701:Dennd4a
|
APN |
9 |
64,897,353 (GRCm38) |
missense |
possibly damaging |
0.50 |
|
IGL03051:Dennd4a
|
APN |
9 |
64,862,414 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03257:Dennd4a
|
APN |
9 |
64,871,874 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
IGL03346:Dennd4a
|
APN |
9 |
64,888,526 (GRCm38) |
missense |
possibly damaging |
0.47 |
|
IGL03349:Dennd4a
|
APN |
9 |
64,888,974 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03398:Dennd4a
|
APN |
9 |
64,871,882 (GRCm38) |
missense |
probably benign |
0.32 |
|
R0010:Dennd4a
|
UTSW |
9 |
64,896,715 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0010:Dennd4a
|
UTSW |
9 |
64,896,715 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0129:Dennd4a
|
UTSW |
9 |
64,893,294 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0220:Dennd4a
|
UTSW |
9 |
64,852,445 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0396:Dennd4a
|
UTSW |
9 |
64,862,391 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0881:Dennd4a
|
UTSW |
9 |
64,851,383 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1225:Dennd4a
|
UTSW |
9 |
64,911,675 (GRCm38) |
missense |
probably benign |
0.03 |
|
R1311:Dennd4a
|
UTSW |
9 |
64,910,004 (GRCm38) |
missense |
probably benign |
0.34 |
|
R1448:Dennd4a
|
UTSW |
9 |
64,906,045 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R1450:Dennd4a
|
UTSW |
9 |
64,911,665 (GRCm38) |
missense |
probably benign |
0.03 |
|
R1630:Dennd4a
|
UTSW |
9 |
64,871,882 (GRCm38) |
missense |
probably benign |
0.32 |
|
R1709:Dennd4a
|
UTSW |
9 |
64,889,605 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R1824:Dennd4a
|
UTSW |
9 |
64,859,358 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1851:Dennd4a
|
UTSW |
9 |
64,862,030 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1870:Dennd4a
|
UTSW |
9 |
64,897,234 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1900:Dennd4a
|
UTSW |
9 |
64,897,336 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1911:Dennd4a
|
UTSW |
9 |
64,889,086 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1938:Dennd4a
|
UTSW |
9 |
64,842,490 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1954:Dennd4a
|
UTSW |
9 |
64,852,467 (GRCm38) |
missense |
probably benign |
0.02 |
|
R1955:Dennd4a
|
UTSW |
9 |
64,852,467 (GRCm38) |
missense |
probably benign |
0.02 |
|
R2049:Dennd4a
|
UTSW |
9 |
64,889,605 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R2129:Dennd4a
|
UTSW |
9 |
64,905,974 (GRCm38) |
splice site |
probably null |
|
|
R2138:Dennd4a
|
UTSW |
9 |
64,889,337 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2929:Dennd4a
|
UTSW |
9 |
64,852,417 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
R3083:Dennd4a
|
UTSW |
9 |
64,906,081 (GRCm38) |
missense |
probably benign |
0.03 |
|
R3108:Dennd4a
|
UTSW |
9 |
64,912,387 (GRCm38) |
missense |
probably benign |
0.23 |
|
R3176:Dennd4a
|
UTSW |
9 |
64,888,993 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3177:Dennd4a
|
UTSW |
9 |
64,888,993 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3276:Dennd4a
|
UTSW |
9 |
64,888,993 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3277:Dennd4a
|
UTSW |
9 |
64,888,993 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3890:Dennd4a
|
UTSW |
9 |
64,872,028 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3953:Dennd4a
|
UTSW |
9 |
64,852,575 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3963:Dennd4a
|
UTSW |
9 |
64,862,331 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4059:Dennd4a
|
UTSW |
9 |
64,911,892 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R4499:Dennd4a
|
UTSW |
9 |
64,910,123 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R4500:Dennd4a
|
UTSW |
9 |
64,910,123 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R4501:Dennd4a
|
UTSW |
9 |
64,910,123 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R4671:Dennd4a
|
UTSW |
9 |
64,894,407 (GRCm38) |
missense |
probably benign |
|
|
R4701:Dennd4a
|
UTSW |
9 |
64,897,357 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R4821:Dennd4a
|
UTSW |
9 |
64,897,249 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R4829:Dennd4a
|
UTSW |
9 |
64,889,056 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4876:Dennd4a
|
UTSW |
9 |
64,896,590 (GRCm38) |
missense |
probably benign |
|
|
R4881:Dennd4a
|
UTSW |
9 |
64,838,844 (GRCm38) |
missense |
possibly damaging |
0.77 |
|
R4962:Dennd4a
|
UTSW |
9 |
64,906,003 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5225:Dennd4a
|
UTSW |
9 |
64,888,928 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R5557:Dennd4a
|
UTSW |
9 |
64,904,227 (GRCm38) |
missense |
probably benign |
0.07 |
|
R5649:Dennd4a
|
UTSW |
9 |
64,851,209 (GRCm38) |
splice site |
probably null |
|
|
R5868:Dennd4a
|
UTSW |
9 |
64,896,729 (GRCm38) |
missense |
probably benign |
0.02 |
|
R5876:Dennd4a
|
UTSW |
9 |
64,911,755 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6052:Dennd4a
|
UTSW |
9 |
64,886,945 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6411:Dennd4a
|
UTSW |
9 |
64,871,899 (GRCm38) |
missense |
probably benign |
0.04 |
|
R6596:Dennd4a
|
UTSW |
9 |
64,852,420 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6668:Dennd4a
|
UTSW |
9 |
64,886,965 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6915:Dennd4a
|
UTSW |
9 |
64,852,489 (GRCm38) |
nonsense |
probably null |
|
|
R7056:Dennd4a
|
UTSW |
9 |
64,906,923 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
R7107:Dennd4a
|
UTSW |
9 |
64,894,399 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
R7203:Dennd4a
|
UTSW |
9 |
64,896,474 (GRCm38) |
missense |
probably benign |
0.05 |
|
R7238:Dennd4a
|
UTSW |
9 |
64,861,956 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7373:Dennd4a
|
UTSW |
9 |
64,897,269 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7454:Dennd4a
|
UTSW |
9 |
64,852,570 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7546:Dennd4a
|
UTSW |
9 |
64,873,044 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7590:Dennd4a
|
UTSW |
9 |
64,888,587 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7662:Dennd4a
|
UTSW |
9 |
64,852,431 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7909:Dennd4a
|
UTSW |
9 |
64,872,993 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
R7976:Dennd4a
|
UTSW |
9 |
64,852,512 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R8026:Dennd4a
|
UTSW |
9 |
64,873,030 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8034:Dennd4a
|
UTSW |
9 |
64,888,568 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8089:Dennd4a
|
UTSW |
9 |
64,849,175 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8298:Dennd4a
|
UTSW |
9 |
64,906,875 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8397:Dennd4a
|
UTSW |
9 |
64,889,109 (GRCm38) |
missense |
probably benign |
|
|
R8425:Dennd4a
|
UTSW |
9 |
64,838,974 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8495:Dennd4a
|
UTSW |
9 |
64,886,879 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8855:Dennd4a
|
UTSW |
9 |
64,912,390 (GRCm38) |
missense |
probably benign |
|
|
R9219:Dennd4a
|
UTSW |
9 |
64,889,094 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R9275:Dennd4a
|
UTSW |
9 |
64,842,624 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9376:Dennd4a
|
UTSW |
9 |
64,912,692 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9485:Dennd4a
|
UTSW |
9 |
64,907,106 (GRCm38) |
nonsense |
probably null |
|
|
R9672:Dennd4a
|
UTSW |
9 |
64,893,358 (GRCm38) |
missense |
probably benign |
|
|
R9746:Dennd4a
|
UTSW |
9 |
64,894,511 (GRCm38) |
missense |
probably benign |
|
|
X0026:Dennd4a
|
UTSW |
9 |
64,897,320 (GRCm38) |
missense |
possibly damaging |
0.67 |
|
Z1088:Dennd4a
|
UTSW |
9 |
64,872,022 (GRCm38) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- CATGTGGCTGTATTTGCTCAGATC -3'
(R):5'- CTGTTGATGAGCTGGACTTCAAG -3'
Sequencing Primer
(F):5'- GCTCAGATCTTTTGATTATTGCCATG -3'
(R):5'- GATGAGCTGGACTTCAAGAAATATC -3'
|
| Posted On |
2019-11-26 |
Incidental Mutation