Mutagenetix > Incidental Mutation

Incidental Mutation 'R7788:Lmo7'

599693

Institutional Source

Beutler Lab

Gene Symbol

Lmo7

Ensembl Gene

ENSMUSG00000033060

Gene Name

LIM domain only 7

Synonyms

FBXO20, LOC380928

MMRRC Submission

045844-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.141) question?

Stock #

R7788 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

101967393-102172146 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to C at 102136012 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Asparagine to Threonine at position 695 (N695T)

Ref Sequence

ENSEMBL: ENSMUSP00000097910 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000100337] [ENSMUST00000159026] [ENSMUST00000159258] [ENSMUST00000159314] [ENSMUST00000159597]

AlphaFold

E9PYF4

Predicted Effect

possibly damaging
Transcript: ENSMUST00000100337
AA Change: N695T

PolyPhen 2 Score 0.638 (Sensitivity: 0.87; Specificity: 0.91)

SMART Domains

Protein: ENSMUSP00000097910
Gene: ENSMUSG00000033060
AA Change: N695T

Domain	Start	End	E-Value	Type
CH	14	124	2.57e-13	SMART
low complexity region	200	211	N/A	INTRINSIC
Pfam:DUF4757	242	348	2.2e-14	PFAM
low complexity region	448	462	N/A	INTRINSIC
Pfam:DUF4757	568	735	1.8e-46	PFAM
low complexity region	861	879	N/A	INTRINSIC
low complexity region	979	991	N/A	INTRINSIC
low complexity region	1003	1015	N/A	INTRINSIC
PDZ	1047	1119	1.05e-8	SMART
coiled coil region	1222	1275	N/A	INTRINSIC
coiled coil region	1319	1411	N/A	INTRINSIC
low complexity region	1585	1596	N/A	INTRINSIC
low complexity region	1599	1617	N/A	INTRINSIC
LIM	1629	1687	6.54e-10	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000159026
AA Change: N462T

PolyPhen 2 Score 0.055 (Sensitivity: 0.94; Specificity: 0.84)

SMART Domains

Protein: ENSMUSP00000124605
Gene: ENSMUSG00000033060
AA Change: N462T

Domain	Start	End	E-Value	Type
low complexity region	215	229	N/A	INTRINSIC
coiled coil region	435	471	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000159258

SMART Domains

Protein: ENSMUSP00000125465
Gene: ENSMUSG00000033060

Domain	Start	End	E-Value	Type
low complexity region	215	229	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000159314
AA Change: N462T

PolyPhen 2 Score 0.026 (Sensitivity: 0.95; Specificity: 0.81)

SMART Domains

Protein: ENSMUSP00000124349
Gene: ENSMUSG00000033060
AA Change: N462T

Domain	Start	End	E-Value	Type
low complexity region	215	229	N/A	INTRINSIC
coiled coil region	435	492	N/A	INTRINSIC
low complexity region	628	646	N/A	INTRINSIC
low complexity region	746	758	N/A	INTRINSIC
low complexity region	770	782	N/A	INTRINSIC
PDZ	814	886	1.05e-8	SMART
coiled coil region	989	1042	N/A	INTRINSIC
coiled coil region	1086	1178	N/A	INTRINSIC
low complexity region	1352	1363	N/A	INTRINSIC
low complexity region	1366	1384	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000159597
AA Change: N573T

PolyPhen 2 Score 0.029 (Sensitivity: 0.95; Specificity: 0.82)

SMART Domains

Protein: ENSMUSP00000123706
Gene: ENSMUSG00000033060
AA Change: N573T

Domain	Start	End	E-Value	Type
low complexity region	78	89	N/A	INTRINSIC
internal_repeat_1	111	141	6.96e-5	PROSPERO
internal_repeat_1	218	248	6.96e-5	PROSPERO
low complexity region	326	340	N/A	INTRINSIC
coiled coil region	546	603	N/A	INTRINSIC
low complexity region	739	757	N/A	INTRINSIC
low complexity region	857	869	N/A	INTRINSIC
low complexity region	881	893	N/A	INTRINSIC
PDZ	925	997	1.05e-8	SMART
coiled coil region	1127	1180	N/A	INTRINSIC
coiled coil region	1224	1316	N/A	INTRINSIC
low complexity region	1490	1501	N/A	INTRINSIC
low complexity region	1504	1522	N/A	INTRINSIC
LIM	1534	1592	6.54e-10	SMART

Predicted Effect

SMART Domains

Protein: ENSMUSP00000124300
Gene: ENSMUSG00000033060
AA Change: N184T

Domain	Start	End	E-Value	Type
low complexity region	34	45	N/A	INTRINSIC
Pfam:DUF4757	76	225	4.5e-53	PFAM
low complexity region	351	369	N/A	INTRINSIC
low complexity region	469	481	N/A	INTRINSIC
low complexity region	493	505	N/A	INTRINSIC
PDZ	537	609	1.05e-8	SMART
internal_repeat_1	620	691	9.31e-5	PROSPERO
coiled coil region	711	764	N/A	INTRINSIC
coiled coil region	808	900	N/A	INTRINSIC
internal_repeat_1	921	976	9.31e-5	PROSPERO
low complexity region	1075	1086	N/A	INTRINSIC
low complexity region	1089	1107	N/A	INTRINSIC
LIM	1119	1177	6.54e-10	SMART

Meta Mutation Damage Score

0.1712

Coding Region Coverage

1x: 100.0%
3x: 100.0%
10x: 99.7%
20x: 99.2%

Validation Efficiency

99% (68/69)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein containing a calponin homology (CH) domain, a PDZ domain, and a LIM domain, and may be involved in protein-protein interactions. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene, however, the full-length nature of some variants is not known. [provided by RefSeq, Jan 2009]
PHENOTYPE: Targeted mutations in this gene result in postnatal lethality, growth defects, skeletal muscle abnormalities and retinal defects reflective of retinal degeneration. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 70 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adam7	A	T	14: 68,750,094 (GRCm39)	V442E	possibly damaging	Het
Adgrv1	A	T	13: 81,721,433 (GRCm39)	V715D	probably damaging	Het
Aldh1l1	A	C	6: 90,546,894 (GRCm39)	D399A	probably benign	Het
Ankrd23	T	C	1: 36,570,808 (GRCm39)	N274S	probably damaging	Het
Aopep	A	T	13: 63,304,407 (GRCm39)	H473L	possibly damaging	Het
Arid5b	C	T	10: 67,934,417 (GRCm39)	G495E	probably benign	Het
Arpc4	A	T	6: 113,362,565 (GRCm39)	M149L	probably benign	Het
Bdp1	T	C	13: 100,191,759 (GRCm39)	T1407A	possibly damaging	Het
Calml3	A	T	13: 3,854,121 (GRCm39)	I28N	probably damaging	Het
Cdhr3	A	G	12: 33,110,319 (GRCm39)	S322P	probably damaging	Het
Cilk1	G	C	9: 78,074,902 (GRCm39)	V586L	probably benign	Het
Cntn5	A	G	9: 9,704,934 (GRCm39)	S622P	probably benign	Het
Col22a1	A	G	15: 71,824,166 (GRCm39)		probably null	Het
Csf2rb2	A	T	15: 78,177,041 (GRCm39)	I143N	probably benign	Het
Cwh43	T	C	5: 73,572,377 (GRCm39)	L205P	probably damaging	Het
Dennd5b	T	C	6: 148,970,064 (GRCm39)	T52A	probably benign	Het
Dhx40	A	G	11: 86,666,502 (GRCm39)	I597T	possibly damaging	Het
Dnajc21	A	G	15: 10,460,133 (GRCm39)	L268P	probably damaging	Het
Dzip1	A	T	14: 119,120,805 (GRCm39)	D717E	probably benign	Het
Elmo3	A	G	8: 106,034,876 (GRCm39)	N389D	probably damaging	Het
Evi2a	T	C	11: 79,418,768 (GRCm39)	E14G	unknown	Het
Fam149a	T	A	8: 45,834,554 (GRCm39)	R82W	probably damaging	Het
Farp1	A	T	14: 121,513,665 (GRCm39)	E820V	probably benign	Het
Fgd5	T	A	6: 91,965,440 (GRCm39)	S400T	possibly damaging	Het
Flnc	G	A	6: 29,456,443 (GRCm39)	V2214I	possibly damaging	Het
Galnt4	C	A	10: 98,944,975 (GRCm39)	N233K	possibly damaging	Het
Gbp5	A	G	3: 142,208,841 (GRCm39)	Y128C	probably damaging	Het
Gm4871	G	A	5: 144,969,420 (GRCm39)	T33I	probably benign	Het
Gm5592	T	C	7: 40,936,118 (GRCm39)	S207P	probably benign	Het
Gtf2ird1	A	T	5: 134,445,985 (GRCm39)	C15*	probably null	Het
Ido2	T	A	8: 25,037,242 (GRCm39)	I155F	probably damaging	Het
Ifi27l2b	A	T	12: 103,423,268 (GRCm39)		probably null	Het
Il15ra	C	T	2: 11,728,404 (GRCm39)	T49I	probably damaging	Het
Itpr3	T	A	17: 27,337,571 (GRCm39)	C2460*	probably null	Het
Kcnj11	T	C	7: 45,749,179 (GRCm39)	N48S	probably damaging	Het
Mmp15	C	A	8: 96,094,776 (GRCm39)	H217N	probably damaging	Het
Mtcl2	C	T	2: 156,869,504 (GRCm39)	A1044T	probably benign	Het
Muc21	A	T	17: 35,929,798 (GRCm39)	S1463T	unknown	Het
Mug1	C	A	6: 121,838,179 (GRCm39)	H470N	possibly damaging	Het
Myo5c	A	T	9: 75,186,627 (GRCm39)	D991V	probably damaging	Het
Nfkbid	T	A	7: 30,126,603 (GRCm39)	N396K	probably damaging	Het
Oas1c	A	G	5: 120,939,107 (GRCm39)	F361L	probably benign	Het
Or10aa1	A	G	1: 173,869,650 (GRCm39)	I45V	probably benign	Het
Or1e1b-ps1	A	T	11: 73,845,948 (GRCm39)	Y144F	probably benign	Het
Osbpl9	T	C	4: 108,919,691 (GRCm39)	K606E	probably benign	Het
Pkp2	C	A	16: 16,043,272 (GRCm39)	L111I	probably benign	Het
Pogz	A	G	3: 94,782,544 (GRCm39)	Y635C	probably damaging	Het
Prdx2	A	G	8: 85,698,303 (GRCm39)	T165A	probably benign	Het
Ptcd3	T	C	6: 71,862,541 (GRCm39)	I465V	probably benign	Het
Ptprd	G	A	4: 75,916,841 (GRCm39)	T770I	probably damaging	Het
Rapgef6	A	G	11: 54,585,225 (GRCm39)	Y1541C	probably damaging	Het
Rilpl1	A	T	5: 124,634,200 (GRCm39)		probably null	Het
Rimbp3	T	A	16: 17,030,568 (GRCm39)	Y1331N	probably benign	Het
Sav1	T	C	12: 70,030,995 (GRCm39)	R176G	probably damaging	Het
Sirt5	A	G	13: 43,536,623 (GRCm39)	H219R	probably benign	Het
Skint5	T	G	4: 113,403,715 (GRCm39)	D1169A	unknown	Het
Slfn9	G	T	11: 82,873,467 (GRCm39)	Q479K	possibly damaging	Het
Spata31f1e	A	T	4: 42,793,546 (GRCm39)	H195Q	possibly damaging	Het
Susd4	T	C	1: 182,722,767 (GRCm39)	I483T	possibly damaging	Het
Tmem156	C	T	5: 65,232,912 (GRCm39)	V217I	possibly damaging	Het
Tmem79	A	G	3: 88,239,949 (GRCm39)	Y254H	probably benign	Het
Tmprss2	T	A	16: 97,377,429 (GRCm39)	K223*	probably null	Het
Trav3-1	T	C	14: 52,818,581 (GRCm39)	V85A	probably damaging	Het
Ttn	T	C	2: 76,716,100 (GRCm39)		probably null	Het
Vmn2r22	T	C	6: 123,614,559 (GRCm39)	I344V	not run	Het
Vps13c	A	T	9: 67,847,765 (GRCm39)	M2176L	probably benign	Het
Wdfy3	A	T	5: 101,996,223 (GRCm39)	V3213D	probably damaging	Het
Zbtb21	G	A	16: 97,752,654 (GRCm39)	T543M	possibly damaging	Het
Zc3hav1	A	T	6: 38,309,691 (GRCm39)	V377D	probably benign	Het
Zswim3	T	C	2: 164,661,699 (GRCm39)	C60R	probably damaging	Het

Other mutations in Lmo7

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00569:Lmo7	APN	14	102,124,487 (GRCm39)	missense	probably damaging	0.99
IGL00733:Lmo7	APN	14	102,153,138 (GRCm39)	missense	probably damaging	1.00
IGL00778:Lmo7	APN	14	102,148,321 (GRCm39)	splice site	probably benign
IGL01014:Lmo7	APN	14	102,157,993 (GRCm39)	splice site	probably benign
IGL01401:Lmo7	APN	14	102,031,713 (GRCm39)	nonsense	probably null
IGL01550:Lmo7	APN	14	102,163,576 (GRCm39)	utr 3 prime	probably benign
IGL01570:Lmo7	APN	14	102,139,807 (GRCm39)	critical splice donor site	probably null
IGL01602:Lmo7	APN	14	102,148,192 (GRCm39)	splice site	probably benign
IGL01605:Lmo7	APN	14	102,148,192 (GRCm39)	splice site	probably benign
IGL02012:Lmo7	APN	14	102,126,152 (GRCm39)	intron	probably benign
IGL02145:Lmo7	APN	14	102,139,659 (GRCm39)	missense	probably benign	0.00
IGL02236:Lmo7	APN	14	102,163,524 (GRCm39)	splice site	probably benign
IGL02318:Lmo7	APN	14	102,137,502 (GRCm39)	splice site	probably benign
IGL02345:Lmo7	APN	14	102,124,909 (GRCm39)	missense	probably damaging	1.00
IGL02498:Lmo7	APN	14	102,044,918 (GRCm39)	missense	probably benign	0.01
IGL02583:Lmo7	APN	14	102,171,360 (GRCm39)	utr 3 prime	probably benign
IGL02670:Lmo7	APN	14	102,118,416 (GRCm39)	missense	probably damaging	1.00
IGL02694:Lmo7	APN	14	102,124,606 (GRCm39)	missense	probably damaging	1.00
IGL03026:Lmo7	APN	14	102,166,769 (GRCm39)	utr 3 prime	probably benign
IGL03062:Lmo7	APN	14	102,149,515 (GRCm39)	missense	possibly damaging	0.66
IGL03068:Lmo7	APN	14	102,112,928 (GRCm39)	unclassified	probably benign
IGL03178:Lmo7	APN	14	102,166,696 (GRCm39)	nonsense	probably null
IGL03279:Lmo7	APN	14	102,137,944 (GRCm39)	missense	probably benign	0.30
PIT4458001:Lmo7	UTSW	14	102,124,923 (GRCm39)	nonsense	probably null
R0029:Lmo7	UTSW	14	102,171,357 (GRCm39)	utr 3 prime	probably benign
R0112:Lmo7	UTSW	14	102,124,629 (GRCm39)	nonsense	probably null
R0345:Lmo7	UTSW	14	102,114,313 (GRCm39)	missense	probably damaging	1.00
R0372:Lmo7	UTSW	14	102,155,489 (GRCm39)	splice site	probably benign
R0393:Lmo7	UTSW	14	102,137,892 (GRCm39)	missense	probably benign
R0514:Lmo7	UTSW	14	102,133,995 (GRCm39)	missense	probably damaging	1.00
R0514:Lmo7	UTSW	14	102,124,609 (GRCm39)	missense	probably damaging	1.00
R0526:Lmo7	UTSW	14	102,137,996 (GRCm39)	missense	probably damaging	1.00
R0615:Lmo7	UTSW	14	102,114,295 (GRCm39)	nonsense	probably null
R0900:Lmo7	UTSW	14	102,124,624 (GRCm39)	missense	probably damaging	1.00
R0961:Lmo7	UTSW	14	102,031,705 (GRCm39)	missense	probably benign	0.00
R0964:Lmo7	UTSW	14	102,158,003 (GRCm39)	splice site	probably benign
R1078:Lmo7	UTSW	14	102,157,910 (GRCm39)	splice site	probably benign
R1252:Lmo7	UTSW	14	102,138,019 (GRCm39)	missense	probably damaging	1.00
R1527:Lmo7	UTSW	14	102,114,264 (GRCm39)	missense	probably damaging	1.00
R1537:Lmo7	UTSW	14	102,166,700 (GRCm39)	utr 3 prime	probably benign
R1565:Lmo7	UTSW	14	102,124,957 (GRCm39)	missense	probably damaging	0.99
R1637:Lmo7	UTSW	14	102,118,268 (GRCm39)	missense	probably damaging	1.00
R1943:Lmo7	UTSW	14	102,139,738 (GRCm39)	missense	probably damaging	1.00
R1967:Lmo7	UTSW	14	102,137,651 (GRCm39)	missense	probably benign	0.36
R2002:Lmo7	UTSW	14	102,124,497 (GRCm39)	missense	probably benign	0.13
R2057:Lmo7	UTSW	14	102,124,614 (GRCm39)	missense	probably damaging	1.00
R2131:Lmo7	UTSW	14	102,137,674 (GRCm39)	missense	probably damaging	0.99
R2153:Lmo7	UTSW	14	102,157,951 (GRCm39)	utr 3 prime	probably benign
R2257:Lmo7	UTSW	14	102,137,566 (GRCm39)	missense	probably damaging	1.00
R2355:Lmo7	UTSW	14	102,126,121 (GRCm39)	missense	probably damaging	1.00
R2356:Lmo7	UTSW	14	102,124,381 (GRCm39)	missense	probably damaging	1.00
R2898:Lmo7	UTSW	14	102,114,350 (GRCm39)	missense	possibly damaging	0.93
R3847:Lmo7	UTSW	14	102,159,531 (GRCm39)	critical splice acceptor site	probably null
R3848:Lmo7	UTSW	14	102,159,531 (GRCm39)	critical splice acceptor site	probably null
R3849:Lmo7	UTSW	14	102,159,531 (GRCm39)	critical splice acceptor site	probably null
R3916:Lmo7	UTSW	14	102,166,778 (GRCm39)	utr 3 prime	probably benign
R4050:Lmo7	UTSW	14	102,139,713 (GRCm39)	nonsense	probably null
R4326:Lmo7	UTSW	14	102,137,510 (GRCm39)	missense	possibly damaging	0.93
R4357:Lmo7	UTSW	14	102,125,091 (GRCm39)	missense	probably null	1.00
R4571:Lmo7	UTSW	14	102,125,030 (GRCm39)	missense	probably damaging	0.96
R4658:Lmo7	UTSW	14	102,124,393 (GRCm39)	missense	probably damaging	1.00
R4857:Lmo7	UTSW	14	102,124,784 (GRCm39)	splice site	probably null
R5006:Lmo7	UTSW	14	102,163,673 (GRCm39)	utr 3 prime	probably benign
R5528:Lmo7	UTSW	14	102,139,522 (GRCm39)	missense	probably damaging	1.00
R5588:Lmo7	UTSW	14	102,134,026 (GRCm39)	splice site	probably null
R5643:Lmo7	UTSW	14	102,166,772 (GRCm39)	utr 3 prime	probably benign
R5644:Lmo7	UTSW	14	102,166,772 (GRCm39)	utr 3 prime	probably benign
R5650:Lmo7	UTSW	14	102,136,110 (GRCm39)	missense	probably damaging	1.00
R5737:Lmo7	UTSW	14	102,124,672 (GRCm39)	missense	probably damaging	1.00
R5832:Lmo7	UTSW	14	102,121,649 (GRCm39)	missense	probably damaging	1.00
R5966:Lmo7	UTSW	14	102,137,938 (GRCm39)	missense	possibly damaging	0.92
R6026:Lmo7	UTSW	14	102,118,426 (GRCm39)	missense	probably benign	0.04
R6072:Lmo7	UTSW	14	102,166,772 (GRCm39)	utr 3 prime	probably benign
R6158:Lmo7	UTSW	14	102,137,573 (GRCm39)	missense	probably benign	0.03
R6246:Lmo7	UTSW	14	102,156,136 (GRCm39)	missense	probably damaging	1.00
R6335:Lmo7	UTSW	14	102,138,072 (GRCm39)	missense	probably damaging	1.00
R6620:Lmo7	UTSW	14	102,112,888 (GRCm39)	missense	probably benign	0.29
R6658:Lmo7	UTSW	14	102,148,281 (GRCm39)	missense	possibly damaging	0.84
R6917:Lmo7	UTSW	14	102,155,446 (GRCm39)	missense	probably damaging	1.00
R7064:Lmo7	UTSW	14	102,121,615 (GRCm39)	missense	probably damaging	1.00
R7072:Lmo7	UTSW	14	102,136,136 (GRCm39)	critical splice donor site	probably null
R7121:Lmo7	UTSW	14	102,124,471 (GRCm39)	missense	probably damaging	1.00
R7136:Lmo7	UTSW	14	102,157,975 (GRCm39)	missense	unknown
R7196:Lmo7	UTSW	14	102,133,936 (GRCm39)	missense	possibly damaging	0.75
R7228:Lmo7	UTSW	14	102,133,971 (GRCm39)	missense	probably damaging	0.99
R7337:Lmo7	UTSW	14	102,121,640 (GRCm39)	missense	probably damaging	0.98
R7341:Lmo7	UTSW	14	102,122,948 (GRCm39)	missense	probably benign	0.30
R7408:Lmo7	UTSW	14	102,118,389 (GRCm39)	missense	probably damaging	1.00
R7432:Lmo7	UTSW	14	102,139,551 (GRCm39)	missense	probably benign	0.42
R7470:Lmo7	UTSW	14	102,138,040 (GRCm39)	missense	possibly damaging	0.83
R7506:Lmo7	UTSW	14	102,157,045 (GRCm39)	missense	unknown
R7559:Lmo7	UTSW	14	102,124,662 (GRCm39)	nonsense	probably null
R7565:Lmo7	UTSW	14	102,122,737 (GRCm39)	missense	probably damaging	0.98
R8095:Lmo7	UTSW	14	102,124,855 (GRCm39)	missense	possibly damaging	0.88
R8100:Lmo7	UTSW	14	102,137,899 (GRCm39)	missense	probably benign	0.33
R8121:Lmo7	UTSW	14	102,163,736 (GRCm39)	missense	unknown
R8308:Lmo7	UTSW	14	102,139,807 (GRCm39)	critical splice donor site	probably null
R8371:Lmo7	UTSW	14	102,124,444 (GRCm39)	missense	possibly damaging	0.95
R8403:Lmo7	UTSW	14	102,139,800 (GRCm39)	missense	probably benign	0.03
R8690:Lmo7	UTSW	14	102,168,644 (GRCm39)	missense	unknown
R8778:Lmo7	UTSW	14	102,156,655 (GRCm39)	missense	probably benign	0.24
R8778:Lmo7	UTSW	14	102,149,503 (GRCm39)	missense	probably damaging	0.98
R8822:Lmo7	UTSW	14	102,121,610 (GRCm39)	missense	probably damaging	1.00
R8849:Lmo7	UTSW	14	102,163,543 (GRCm39)	missense	unknown
R8923:Lmo7	UTSW	14	102,137,679 (GRCm39)	missense	probably benign	0.31
R9006:Lmo7	UTSW	14	102,155,072 (GRCm39)	small deletion	probably benign
R9135:Lmo7	UTSW	14	102,118,297 (GRCm39)	missense	probably damaging	1.00
R9154:Lmo7	UTSW	14	102,122,743 (GRCm39)	missense	probably damaging	0.99
R9178:Lmo7	UTSW	14	102,044,906 (GRCm39)	nonsense	probably null
R9375:Lmo7	UTSW	14	102,136,123 (GRCm39)	missense	probably damaging	0.99
R9428:Lmo7	UTSW	14	102,155,076 (GRCm39)	missense	probably damaging	0.99
R9488:Lmo7	UTSW	14	102,122,783 (GRCm39)	missense	possibly damaging	0.85
R9493:Lmo7	UTSW	14	102,137,907 (GRCm39)	missense	probably benign	0.01
R9594:Lmo7	UTSW	14	102,156,136 (GRCm39)	missense	probably null	0.98
R9674:Lmo7	UTSW	14	102,078,340 (GRCm39)	missense	probably damaging	1.00
R9736:Lmo7	UTSW	14	102,157,929 (GRCm39)	missense	unknown
X0066:Lmo7	UTSW	14	102,124,897 (GRCm39)	missense	probably damaging	1.00
X0067:Lmo7	UTSW	14	102,124,369 (GRCm39)	splice site	probably null
Z1176:Lmo7	UTSW	14	102,156,717 (GRCm39)	missense	probably benign	0.00
Z1176:Lmo7	UTSW	14	102,121,742 (GRCm39)	missense	probably damaging	0.99
Z1176:Lmo7	UTSW	14	102,166,664 (GRCm39)	missense	unknown
Z1176:Lmo7	UTSW	14	102,156,879 (GRCm39)	missense	unknown
Z1177:Lmo7	UTSW	14	102,135,993 (GRCm39)	missense	probably damaging	1.00
Z1177:Lmo7	UTSW	14	102,133,954 (GRCm39)	missense	possibly damaging	0.96

Predicted Primers

PCR Primer
(F):5'- TTTTCCGGCAGACACATGAG -3'
(R):5'- ACCACATACAAAGCCTGTGTTC -3'

Sequencing Primer
(F):5'- TTTTCCGGCAGACACATGAGATAAAG -3'
(R):5'- AAAGCCTGTGTTCCCAGC -3'

Posted On

2019-11-26