Mutagenetix > Incidental Mutation

Incidental Mutation 'R7798:Abca13'

600375

Institutional Source

Beutler Lab

Gene Symbol

Abca13

Ensembl Gene

ENSMUSG00000004668

Gene Name

ATP-binding cassette, sub-family A (ABC1), member 13

Synonyms

A930002G16Rik

MMRRC Submission

045648-MU

Accession Numbers

NCBI RefSeq: NM_178259.3; MGI:2388707

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R7798 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

9191942-9684259 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 9291664 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Threonine to Alanine at position 1176 (T1176A)

Ref Sequence

ENSEMBL: ENSMUSP00000040465 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000042740]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000042740
AA Change: T1176A

PolyPhen 2 Score 0.038 (Sensitivity: 0.94; Specificity: 0.82)

SMART Domains

Protein: ENSMUSP00000040465
Gene: ENSMUSG00000004668
AA Change: T1176A

Domain	Start	End	E-Value	Type
transmembrane domain	20	42	N/A	INTRINSIC
low complexity region	358	379	N/A	INTRINSIC
low complexity region	441	451	N/A	INTRINSIC
low complexity region	820	831	N/A	INTRINSIC
low complexity region	1382	1393	N/A	INTRINSIC
low complexity region	1721	1737	N/A	INTRINSIC
low complexity region	1859	1872	N/A	INTRINSIC
Pfam:ABC2_membrane_3	3288	3740	4.7e-21	PFAM
low complexity region	3796	3809	N/A	INTRINSIC
AAA	3835	4019	8.08e-12	SMART
transmembrane domain	4206	4228	N/A	INTRINSIC
Pfam:ABC2_membrane_3	4317	4646	1.6e-33	PFAM
AAA	4721	4909	8.86e-9	SMART

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.6%
20x: 98.7%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] In human, the ATP-binding cassette (ABC) family of transmembrane transporters has at least 48 genes and 7 gene subfamilies. This gene is a member of ABC gene subfamily A (ABCA). Genes within the ABCA family typically encode several thousand amino acids. Like other ABC transmembrane transporter proteins, this protein has 12 or more transmembrane alpha-helix domains that likely arrange to form a single central chamber with multiple substrate binding sites. It is also predicted to have two large extracellular domains and two nucleotide binding domains as is typical for ABCA proteins. Alternative splice variants have been described but their biological validity has not been demonstrated.[provided by RefSeq, Mar 2009]

Allele List at MGI

All alleles(3) : Targeted(3)

Other mutations in this stock

Total: 77 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700088E04Rik	T	A	15: 79,135,732 (GRCm38)	N128I	probably damaging	Het
5830473C10Rik	T	C	5: 90,597,511 (GRCm38)	S608P	possibly damaging	Het
Abca9	A	G	11: 110,138,179 (GRCm38)	V851A	probably benign	Het
Abcc6	C	A	7: 45,976,853 (GRCm38)	E1494*	probably null	Het
Adamts14	A	T	10: 61,271,173 (GRCm38)	V56E	probably damaging	Het
Adamts15	G	A	9: 30,904,643 (GRCm38)	T639M	probably damaging	Het
Arhgap11a	A	C	2: 113,843,335 (GRCm38)	V70G	probably damaging	Het
BC051665	A	T	13: 60,784,435 (GRCm38)	D113E	probably benign	Het
Best1	T	C	19: 9,991,671 (GRCm38)	Y227C	probably damaging	Het
Camk2b	A	G	11: 5,978,399 (GRCm38)	S447P	probably benign	Het
Ccdc88a	C	A	11: 29,477,348 (GRCm38)	Q1018K	probably benign	Het
Cfap74	T	A	4: 155,422,622 (GRCm38)	V180D		Het
Clca3a1	T	A	3: 144,757,962 (GRCm38)	T185S	probably damaging	Het
Clca3b	T	C	3: 144,828,130 (GRCm38)	S495G	probably damaging	Het
Cyb5r2	A	T	7: 107,753,948 (GRCm38)	Y96N	possibly damaging	Het
Cyp21a1	T	C	17: 34,804,321 (GRCm38)	K27E	probably benign	Het
Cyp2ab1	T	C	16: 20,312,416 (GRCm38)	E321G	probably benign	Het
Des	T	C	1: 75,362,359 (GRCm38)	I228T	probably damaging	Het
Dis3l	G	T	9: 64,341,017 (GRCm38)	P39T	probably benign	Het
Disp2	A	C	2: 118,791,879 (GRCm38)	I1031L	probably benign	Het
Ell3	TCTCCTC	TCTC	2: 121,439,456 (GRCm38)		probably benign	Het
Etl4	G	A	2: 20,781,946 (GRCm38)		probably null	Het
Fgf23	A	T	6: 127,073,214 (GRCm38)	D62V	probably damaging	Het
Galnt15	C	T	14: 32,029,905 (GRCm38)	T138I	possibly damaging	Het
Ggt6	A	T	11: 72,435,541 (GRCm38)		probably benign	Het
Gm28710	T	C	5: 16,856,658 (GRCm38)	F801L	possibly damaging	Het
Gm9573	C	G	17: 35,621,254 (GRCm38)	G680A	unknown	Het
Gpr180	T	A	14: 118,153,686 (GRCm38)	V209D	probably damaging	Het
Gzma	A	T	13: 113,096,324 (GRCm38)	F78Y	probably benign	Het
Igkv8-30	A	T	6: 70,117,371 (GRCm38)	C19S	probably benign	Het
Il1r1	G	A	1: 40,310,366 (GRCm38)	V361I	probably benign	Het
Intu	T	C	3: 40,691,929 (GRCm38)	V598A	probably damaging	Het
Itpr2	A	G	6: 146,386,015 (GRCm38)	F471L	probably benign	Het
Kntc1	T	A	5: 123,786,294 (GRCm38)	V1081E	probably benign	Het
Kntc1	T	A	5: 123,819,117 (GRCm38)	V2163E	possibly damaging	Het
Macf1	T	C	4: 123,378,100 (GRCm38)	K6552E	probably damaging	Het
Marf1	T	C	16: 14,138,451 (GRCm38)	H842R	probably benign	Het
Mgat4b	A	G	11: 50,225,670 (GRCm38)	T10A	possibly damaging	Het
Muc5ac	T	C	7: 141,794,041 (GRCm38)		probably null	Het
Nrk	CGCAGCAGCAGCAGCAGCAGC	CGCAGCAGCAGCAGCAGC	X: 138,982,677 (GRCm38)		probably benign	Het
Nsun4	T	G	4: 116,051,174 (GRCm38)	S730R	possibly damaging	Het
Olfr1112	A	T	2: 87,192,292 (GRCm38)	I202L	probably benign	Het
Olfr1310	A	G	2: 112,008,272 (GRCm38)	F305L	probably benign	Het
Olfr351	T	C	2: 36,860,336 (GRCm38)	E4G	probably benign	Het
Olfr360	A	T	2: 37,069,174 (GRCm38)	S290C	probably damaging	Het
Olfr727	A	T	14: 50,127,438 (GRCm38)	Y287F	probably damaging	Het
Padi3	C	T	4: 140,786,439 (GRCm38)	E653K	probably benign	Het
Pde4a	A	G	9: 21,198,663 (GRCm38)	E280G	possibly damaging	Het
Phactr3	G	A	2: 178,283,910 (GRCm38)	R326H	probably benign	Het
Prob1	G	A	18: 35,653,344 (GRCm38)	P619L	possibly damaging	Het
Ptk2	G	A	15: 73,295,375 (GRCm38)	R368W	probably damaging	Het
Rgs6	A	G	12: 83,069,519 (GRCm38)	T240A	probably benign	Het
Rpa1	A	T	11: 75,312,809 (GRCm38)	Y356N	probably damaging	Het
Rxrb	T	A	17: 34,033,605 (GRCm38)	D165E	probably damaging	Het
Sco1	A	G	11: 67,053,802 (GRCm38)	T84A	possibly damaging	Het
Sepsecs	T	C	5: 52,647,189 (GRCm38)	I380V	probably benign	Het
Sfmbt1	T	A	14: 30,816,802 (GRCm38)	W793R	probably damaging	Het
Slco3a1	A	G	7: 74,318,596 (GRCm38)	S459P	probably benign	Het
Smg1	A	T	7: 118,171,939 (GRCm38)	S1503R	possibly damaging	Het
Sox2	G	A	3: 34,650,642 (GRCm38)	R76H	probably damaging	Het
Spty2d1	G	A	7: 46,996,056 (GRCm38)	S613F	probably damaging	Het
Stab2	A	T	10: 86,957,912 (GRCm38)	Y440N	probably damaging	Het
Syn3	A	G	10: 86,080,253 (GRCm38)	Y290H	probably damaging	Het
Tex15	C	T	8: 33,581,847 (GRCm38)	S2474F	possibly damaging	Het
Tgtp1	A	G	11: 48,987,332 (GRCm38)	F182S	probably benign	Het
Tmcc1	A	T	6: 116,043,578 (GRCm38)	S304R		Het
Tmem130	T	G	5: 144,743,770 (GRCm38)	K275Q	probably damaging	Het
Tmem9	C	A	1: 136,034,189 (GRCm38)	T174K	probably damaging	Het
Ttyh3	C	T	5: 140,634,783 (GRCm38)	R233Q	probably damaging	Het
Twnk	T	C	19: 45,007,668 (GRCm38)	M180T	probably benign	Het
Ube4a	A	G	9: 44,933,331 (GRCm38)	V874A	probably damaging	Het
Ugt2a3	T	C	5: 87,327,723 (GRCm38)	N350S	probably damaging	Het
Vegfa	C	T	17: 46,031,835 (GRCm38)	G19D	probably damaging	Het
Vmn2r2	C	A	3: 64,134,097 (GRCm38)	C399F	possibly damaging	Het
Vmn2r65	A	G	7: 84,946,984 (GRCm38)	F164S	probably damaging	Het
Vmn2r65	G	T	7: 84,946,322 (GRCm38)	P385T	probably benign	Het
Zcchc6	A	T	13: 59,815,575 (GRCm38)	M323K	possibly damaging	Het

Other mutations in Abca13

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00094:Abca13	APN	11	9,297,443 (GRCm38)	missense	probably benign	0.24
IGL00481:Abca13	APN	11	9,290,969 (GRCm38)	missense	probably damaging	0.99
IGL00707:Abca13	APN	11	9,291,586 (GRCm38)	missense	probably damaging	0.99
IGL00755:Abca13	APN	11	9,542,102 (GRCm38)	missense	possibly damaging	0.87
IGL00771:Abca13	APN	11	9,290,870 (GRCm38)	missense	probably damaging	1.00
IGL00802:Abca13	APN	11	9,297,717 (GRCm38)	missense	probably damaging	0.96
IGL00807:Abca13	APN	11	9,378,285 (GRCm38)	missense	probably benign	0.10
IGL00977:Abca13	APN	11	9,399,284 (GRCm38)	missense	probably damaging	1.00
IGL01064:Abca13	APN	11	9,483,855 (GRCm38)	missense	probably benign	0.01
IGL01100:Abca13	APN	11	9,274,673 (GRCm38)	splice site	probably null
IGL01290:Abca13	APN	11	9,256,232 (GRCm38)	missense	probably damaging	1.00
IGL01299:Abca13	APN	11	9,298,743 (GRCm38)	missense	probably benign	0.22
IGL01302:Abca13	APN	11	9,399,470 (GRCm38)	splice site	probably benign
IGL01307:Abca13	APN	11	9,297,159 (GRCm38)	missense	possibly damaging	0.86
IGL01349:Abca13	APN	11	9,292,076 (GRCm38)	missense	probably benign	0.05
IGL01351:Abca13	APN	11	9,267,565 (GRCm38)	missense	probably benign	0.28
IGL01446:Abca13	APN	11	9,403,834 (GRCm38)	missense	probably damaging	0.97
IGL01453:Abca13	APN	11	9,403,834 (GRCm38)	missense	probably damaging	0.97
IGL01461:Abca13	APN	11	9,403,834 (GRCm38)	missense	probably damaging	0.97
IGL01476:Abca13	APN	11	9,403,834 (GRCm38)	missense	probably damaging	0.97
IGL01506:Abca13	APN	11	9,297,447 (GRCm38)	missense	probably benign	0.36
IGL01527:Abca13	APN	11	9,290,788 (GRCm38)	missense	possibly damaging	0.49
IGL01559:Abca13	APN	11	9,309,020 (GRCm38)	missense	possibly damaging	0.82
IGL01580:Abca13	APN	11	9,293,527 (GRCm38)	missense	probably benign	0.00
IGL01679:Abca13	APN	11	9,298,071 (GRCm38)	missense	probably benign	0.07
IGL01731:Abca13	APN	11	9,249,749 (GRCm38)	splice site	probably benign
IGL01762:Abca13	APN	11	9,315,423 (GRCm38)	missense	probably benign	0.18
IGL01781:Abca13	APN	11	9,399,280 (GRCm38)	missense	probably damaging	1.00
IGL01802:Abca13	APN	11	9,292,438 (GRCm38)	missense	probably benign	0.00
IGL01809:Abca13	APN	11	9,290,339 (GRCm38)	missense	probably damaging	0.96
IGL01906:Abca13	APN	11	9,216,225 (GRCm38)	missense	probably damaging	1.00
IGL01928:Abca13	APN	11	9,683,342 (GRCm38)	missense	probably benign	0.13
IGL01940:Abca13	APN	11	9,567,661 (GRCm38)	splice site	probably benign
IGL01993:Abca13	APN	11	9,258,452 (GRCm38)	unclassified	probably benign
IGL02039:Abca13	APN	11	9,297,193 (GRCm38)	nonsense	probably null
IGL02159:Abca13	APN	11	9,314,545 (GRCm38)	missense	probably benign	0.00
IGL02202:Abca13	APN	11	9,288,529 (GRCm38)	missense	possibly damaging	0.55
IGL02268:Abca13	APN	11	9,290,626 (GRCm38)	missense	probably benign	0.00
IGL02332:Abca13	APN	11	9,291,482 (GRCm38)	missense	probably damaging	0.98
IGL02380:Abca13	APN	11	9,291,599 (GRCm38)	missense	possibly damaging	0.73
IGL02466:Abca13	APN	11	9,297,527 (GRCm38)	missense	probably benign	0.00
IGL02505:Abca13	APN	11	9,581,498 (GRCm38)	missense	probably damaging	1.00
IGL02507:Abca13	APN	11	9,399,388 (GRCm38)	missense	probably damaging	1.00
IGL02558:Abca13	APN	11	9,399,387 (GRCm38)	missense	probably damaging	1.00
IGL02581:Abca13	APN	11	9,399,132 (GRCm38)	splice site	probably benign
IGL02586:Abca13	APN	11	9,293,983 (GRCm38)	missense	possibly damaging	0.56
IGL02598:Abca13	APN	11	9,431,898 (GRCm38)	missense	probably damaging	1.00
IGL02747:Abca13	APN	11	9,373,282 (GRCm38)	nonsense	probably null
IGL02893:Abca13	APN	11	9,290,543 (GRCm38)	missense	probably damaging	0.96
IGL02930:Abca13	APN	11	9,378,226 (GRCm38)	missense	possibly damaging	0.86
IGL02967:Abca13	APN	11	9,378,291 (GRCm38)	missense	probably damaging	0.99
IGL02983:Abca13	APN	11	9,290,663 (GRCm38)	missense	probably benign	0.40
IGL02999:Abca13	APN	11	9,581,757 (GRCm38)	splice site	probably benign
IGL03100:Abca13	APN	11	9,258,527 (GRCm38)	missense	probably benign	0.25
IGL03114:Abca13	APN	11	9,528,999 (GRCm38)	missense	probably benign	0.06
IGL03230:Abca13	APN	11	9,294,313 (GRCm38)	missense	probably benign	0.02
IGL03329:Abca13	APN	11	9,298,047 (GRCm38)	missense	probably benign	0.08
IGL03380:Abca13	APN	11	9,298,574 (GRCm38)	missense	probably benign	0.10
IGL02835:Abca13	UTSW	11	9,451,515 (GRCm38)	missense	probably damaging	1.00
PIT4366001:Abca13	UTSW	11	9,294,962 (GRCm38)	missense	probably benign
PIT4458001:Abca13	UTSW	11	9,298,304 (GRCm38)	missense	probably benign	0.05
R0017:Abca13	UTSW	11	9,292,775 (GRCm38)	missense	probably damaging	0.99
R0079:Abca13	UTSW	11	9,293,493 (GRCm38)	missense	probably benign	0.00
R0089:Abca13	UTSW	11	9,292,886 (GRCm38)	missense	possibly damaging	0.76
R0103:Abca13	UTSW	11	9,273,951 (GRCm38)	missense	probably damaging	1.00
R0103:Abca13	UTSW	11	9,273,951 (GRCm38)	missense	probably damaging	1.00
R0113:Abca13	UTSW	11	9,292,114 (GRCm38)	missense	possibly damaging	0.54
R0119:Abca13	UTSW	11	9,298,076 (GRCm38)	missense	probably benign	0.03
R0152:Abca13	UTSW	11	9,581,724 (GRCm38)	missense	probably damaging	0.98
R0255:Abca13	UTSW	11	9,581,545 (GRCm38)	missense	probably damaging	1.00
R0277:Abca13	UTSW	11	9,294,701 (GRCm38)	missense	probably benign	0.25
R0278:Abca13	UTSW	11	9,378,215 (GRCm38)	missense	probably damaging	1.00
R0294:Abca13	UTSW	11	9,269,122 (GRCm38)	splice site	probably null
R0299:Abca13	UTSW	11	9,298,076 (GRCm38)	missense	probably benign	0.03
R0310:Abca13	UTSW	11	9,293,810 (GRCm38)	missense	probably benign	0.36
R0317:Abca13	UTSW	11	9,293,459 (GRCm38)	missense	probably damaging	1.00
R0323:Abca13	UTSW	11	9,294,701 (GRCm38)	missense	probably benign	0.25
R0324:Abca13	UTSW	11	9,297,669 (GRCm38)	missense	possibly damaging	0.76
R0329:Abca13	UTSW	11	9,399,430 (GRCm38)	missense	probably damaging	0.97
R0336:Abca13	UTSW	11	9,298,481 (GRCm38)	missense	probably benign	0.04
R0346:Abca13	UTSW	11	9,566,278 (GRCm38)	missense	probably damaging	0.99
R0380:Abca13	UTSW	11	9,588,500 (GRCm38)	splice site	probably null
R0382:Abca13	UTSW	11	9,636,650 (GRCm38)	splice site	probably benign
R0482:Abca13	UTSW	11	9,328,207 (GRCm38)	missense	possibly damaging	0.88
R0487:Abca13	UTSW	11	9,331,687 (GRCm38)	missense	probably benign	0.07
R0491:Abca13	UTSW	11	9,298,235 (GRCm38)	missense	probably benign	0.02
R0496:Abca13	UTSW	11	9,291,701 (GRCm38)	missense	probably benign	0.01
R0505:Abca13	UTSW	11	9,291,058 (GRCm38)	missense	probably benign	0.00
R0511:Abca13	UTSW	11	9,294,559 (GRCm38)	missense	probably benign
R0525:Abca13	UTSW	11	9,293,371 (GRCm38)	missense	probably damaging	1.00
R0538:Abca13	UTSW	11	9,267,622 (GRCm38)	critical splice donor site	probably null
R0615:Abca13	UTSW	11	9,256,197 (GRCm38)	missense	probably damaging	0.96
R0634:Abca13	UTSW	11	9,314,491 (GRCm38)	missense	possibly damaging	0.59
R0699:Abca13	UTSW	11	9,588,508 (GRCm38)	splice site	probably benign
R0848:Abca13	UTSW	11	9,682,011 (GRCm38)	nonsense	probably null
R0883:Abca13	UTSW	11	9,291,238 (GRCm38)	nonsense	probably null
R0892:Abca13	UTSW	11	9,298,305 (GRCm38)	missense	probably benign	0.00
R0904:Abca13	UTSW	11	9,298,740 (GRCm38)	missense	probably benign	0.22
R0968:Abca13	UTSW	11	9,298,016 (GRCm38)	missense	probably benign	0.00
R1187:Abca13	UTSW	11	9,528,981 (GRCm38)	missense	probably benign	0.00
R1299:Abca13	UTSW	11	9,294,821 (GRCm38)	missense	possibly damaging	0.94
R1323:Abca13	UTSW	11	9,290,937 (GRCm38)	missense	possibly damaging	0.86
R1323:Abca13	UTSW	11	9,290,937 (GRCm38)	missense	possibly damaging	0.86
R1368:Abca13	UTSW	11	9,291,836 (GRCm38)	missense	probably benign
R1387:Abca13	UTSW	11	9,682,085 (GRCm38)	nonsense	probably null
R1436:Abca13	UTSW	11	9,292,646 (GRCm38)	missense	probably damaging	0.99
R1449:Abca13	UTSW	11	9,298,580 (GRCm38)	missense	probably damaging	1.00
R1450:Abca13	UTSW	11	9,430,531 (GRCm38)	splice site	probably benign
R1462:Abca13	UTSW	11	9,483,924 (GRCm38)	splice site	probably benign
R1465:Abca13	UTSW	11	9,399,303 (GRCm38)	missense	probably damaging	1.00
R1465:Abca13	UTSW	11	9,399,303 (GRCm38)	missense	probably damaging	1.00
R1466:Abca13	UTSW	11	9,570,536 (GRCm38)	splice site	probably benign
R1494:Abca13	UTSW	11	9,466,429 (GRCm38)	nonsense	probably null
R1559:Abca13	UTSW	11	9,399,180 (GRCm38)	missense	probably null	1.00
R1564:Abca13	UTSW	11	9,434,316 (GRCm38)	nonsense	probably null
R1698:Abca13	UTSW	11	9,314,507 (GRCm38)	missense	probably benign	0.13
R1728:Abca13	UTSW	11	9,249,680 (GRCm38)	missense	probably benign	0.02
R1734:Abca13	UTSW	11	9,585,460 (GRCm38)	missense	probably benign	0.03
R1781:Abca13	UTSW	11	9,269,194 (GRCm38)	missense	probably damaging	1.00
R1782:Abca13	UTSW	11	9,297,971 (GRCm38)	missense	probably benign	0.36
R1807:Abca13	UTSW	11	9,291,755 (GRCm38)	missense	probably damaging	0.98
R1830:Abca13	UTSW	11	9,290,350 (GRCm38)	missense	probably benign	0.04
R1869:Abca13	UTSW	11	9,292,134 (GRCm38)	missense	probably benign	0.19
R1870:Abca13	UTSW	11	9,292,134 (GRCm38)	missense	probably benign	0.19
R1871:Abca13	UTSW	11	9,292,134 (GRCm38)	missense	probably benign	0.19
R1903:Abca13	UTSW	11	9,466,411 (GRCm38)	missense	probably benign	0.13
R1916:Abca13	UTSW	11	9,534,456 (GRCm38)	missense	probably damaging	1.00
R1936:Abca13	UTSW	11	9,293,595 (GRCm38)	missense	probably benign	0.13
R1976:Abca13	UTSW	11	9,397,815 (GRCm38)	missense	probably damaging	1.00
R2001:Abca13	UTSW	11	9,273,967 (GRCm38)	missense	probably benign	0.01
R2007:Abca13	UTSW	11	9,191,987 (GRCm38)	missense	probably benign	0.19
R2016:Abca13	UTSW	11	9,290,619 (GRCm38)	missense	probably damaging	1.00
R2017:Abca13	UTSW	11	9,290,619 (GRCm38)	missense	probably damaging	1.00
R2034:Abca13	UTSW	11	9,292,628 (GRCm38)	missense	possibly damaging	0.83
R2051:Abca13	UTSW	11	9,328,098 (GRCm38)	missense	probably benign	0.04
R2075:Abca13	UTSW	11	9,522,382 (GRCm38)	missense	probably damaging	1.00
R2118:Abca13	UTSW	11	9,309,013 (GRCm38)	splice site	probably benign
R2120:Abca13	UTSW	11	9,309,013 (GRCm38)	splice site	probably benign
R2124:Abca13	UTSW	11	9,309,013 (GRCm38)	splice site	probably benign
R2148:Abca13	UTSW	11	9,615,764 (GRCm38)	missense	probably damaging	1.00
R2149:Abca13	UTSW	11	9,267,508 (GRCm38)	missense	possibly damaging	0.68
R2157:Abca13	UTSW	11	9,577,170 (GRCm38)	missense	probably damaging	0.97
R2167:Abca13	UTSW	11	9,288,532 (GRCm38)	missense	probably benign	0.19
R2261:Abca13	UTSW	11	9,292,288 (GRCm38)	missense	probably benign
R2263:Abca13	UTSW	11	9,274,702 (GRCm38)	missense	probably benign	0.04
R2281:Abca13	UTSW	11	9,328,136 (GRCm38)	missense	probably damaging	0.98
R2340:Abca13	UTSW	11	9,399,165 (GRCm38)	missense	probably damaging	0.99
R2357:Abca13	UTSW	11	9,297,336 (GRCm38)	missense	probably damaging	1.00
R2370:Abca13	UTSW	11	9,256,185 (GRCm38)	missense	possibly damaging	0.85
R2384:Abca13	UTSW	11	9,267,450 (GRCm38)	splice site	probably benign
R2393:Abca13	UTSW	11	9,275,057 (GRCm38)	nonsense	probably null
R2432:Abca13	UTSW	11	9,451,333 (GRCm38)	splice site	probably benign
R2446:Abca13	UTSW	11	9,275,101 (GRCm38)	missense	probably benign
R2568:Abca13	UTSW	11	9,333,310 (GRCm38)	missense	probably benign	0.40
R2847:Abca13	UTSW	11	9,294,584 (GRCm38)	missense	possibly damaging	0.59
R2860:Abca13	UTSW	11	9,309,057 (GRCm38)	missense	probably damaging	0.99
R2861:Abca13	UTSW	11	9,309,057 (GRCm38)	missense	probably damaging	0.99
R2862:Abca13	UTSW	11	9,309,057 (GRCm38)	missense	probably damaging	0.99
R2877:Abca13	UTSW	11	9,291,889 (GRCm38)	missense	possibly damaging	0.91
R2878:Abca13	UTSW	11	9,291,889 (GRCm38)	missense	possibly damaging	0.91
R3748:Abca13	UTSW	11	9,316,119 (GRCm38)	splice site	probably benign
R3789:Abca13	UTSW	11	9,510,668 (GRCm38)	missense	probably damaging	0.97
R3933:Abca13	UTSW	11	9,354,856 (GRCm38)	missense	probably damaging	1.00
R3981:Abca13	UTSW	11	9,532,407 (GRCm38)	missense	probably benign
R4002:Abca13	UTSW	11	9,585,415 (GRCm38)	missense	probably benign	0.00
R4010:Abca13	UTSW	11	9,622,013 (GRCm38)	splice site	probably benign
R4011:Abca13	UTSW	11	9,622,013 (GRCm38)	splice site	probably benign
R4127:Abca13	UTSW	11	9,191,973 (GRCm38)	missense	probably benign	0.00
R4214:Abca13	UTSW	11	9,293,877 (GRCm38)	missense	probably damaging	0.96
R4236:Abca13	UTSW	11	9,256,205 (GRCm38)	missense	probably damaging	1.00
R4237:Abca13	UTSW	11	9,434,188 (GRCm38)	missense	probably benign	0.01
R4359:Abca13	UTSW	11	9,297,629 (GRCm38)	missense	probably benign	0.02
R4378:Abca13	UTSW	11	9,293,644 (GRCm38)	missense	probably benign	0.00
R4389:Abca13	UTSW	11	9,297,878 (GRCm38)	missense	probably damaging	0.98
R4392:Abca13	UTSW	11	9,309,034 (GRCm38)	missense	possibly damaging	0.94
R4623:Abca13	UTSW	11	9,309,130 (GRCm38)	missense	probably damaging	1.00
R4684:Abca13	UTSW	11	9,434,193 (GRCm38)	nonsense	probably null
R4691:Abca13	UTSW	11	9,434,195 (GRCm38)	missense	probably damaging	1.00
R4700:Abca13	UTSW	11	9,292,306 (GRCm38)	missense	possibly damaging	0.59
R4701:Abca13	UTSW	11	9,292,306 (GRCm38)	missense	possibly damaging	0.59
R4704:Abca13	UTSW	11	9,276,990 (GRCm38)	missense	possibly damaging	0.94
R4751:Abca13	UTSW	11	9,277,973 (GRCm38)	critical splice donor site	probably null
R4772:Abca13	UTSW	11	9,315,339 (GRCm38)	splice site	probably null
R4782:Abca13	UTSW	11	9,328,096 (GRCm38)	missense	probably damaging	0.96
R4801:Abca13	UTSW	11	9,522,341 (GRCm38)	missense	possibly damaging	0.94
R4802:Abca13	UTSW	11	9,522,341 (GRCm38)	missense	possibly damaging	0.94
R4819:Abca13	UTSW	11	9,290,421 (GRCm38)	missense	possibly damaging	0.88
R4831:Abca13	UTSW	11	9,542,077 (GRCm38)	nonsense	probably null
R4851:Abca13	UTSW	11	9,483,890 (GRCm38)	missense	probably benign	0.02
R4857:Abca13	UTSW	11	9,294,143 (GRCm38)	missense	probably benign	0.22
R4869:Abca13	UTSW	11	9,315,434 (GRCm38)	splice site	probably null
R4982:Abca13	UTSW	11	9,292,348 (GRCm38)	missense	possibly damaging	0.58
R5031:Abca13	UTSW	11	9,297,678 (GRCm38)	missense	probably damaging	0.99
R5044:Abca13	UTSW	11	9,373,323 (GRCm38)	missense	possibly damaging	0.80
R5092:Abca13	UTSW	11	9,258,535 (GRCm38)	missense	probably damaging	1.00
R5155:Abca13	UTSW	11	9,532,447 (GRCm38)	missense	probably damaging	0.98
R5173:Abca13	UTSW	11	9,682,032 (GRCm38)	frame shift	probably null
R5180:Abca13	UTSW	11	9,466,510 (GRCm38)	missense	probably benign	0.01
R5244:Abca13	UTSW	11	9,275,081 (GRCm38)	missense	probably benign	0.28
R5257:Abca13	UTSW	11	9,249,684 (GRCm38)	missense	possibly damaging	0.94
R5258:Abca13	UTSW	11	9,249,684 (GRCm38)	missense	possibly damaging	0.94
R5299:Abca13	UTSW	11	9,431,861 (GRCm38)	missense	probably damaging	1.00
R5363:Abca13	UTSW	11	9,277,035 (GRCm38)	missense	possibly damaging	0.75
R5365:Abca13	UTSW	11	9,628,629 (GRCm38)	missense	probably damaging	1.00
R5419:Abca13	UTSW	11	9,193,533 (GRCm38)	critical splice donor site	probably null
R5426:Abca13	UTSW	11	9,290,722 (GRCm38)	missense	probably damaging	1.00
R5468:Abca13	UTSW	11	9,294,062 (GRCm38)	missense	probably damaging	1.00
R5477:Abca13	UTSW	11	9,301,298 (GRCm38)	missense	possibly damaging	0.49
R5541:Abca13	UTSW	11	9,291,545 (GRCm38)	missense	probably benign	0.00
R5553:Abca13	UTSW	11	9,328,158 (GRCm38)	missense	probably damaging	1.00
R5556:Abca13	UTSW	11	9,258,546 (GRCm38)	missense	possibly damaging	0.91
R5566:Abca13	UTSW	11	9,294,615 (GRCm38)	nonsense	probably null
R5582:Abca13	UTSW	11	9,636,639 (GRCm38)	splice site	probably null
R5604:Abca13	UTSW	11	9,566,279 (GRCm38)	missense	probably damaging	0.97
R5609:Abca13	UTSW	11	9,403,874 (GRCm38)	missense	probably benign	0.01
R5617:Abca13	UTSW	11	9,277,891 (GRCm38)	missense	probably benign	0.00
R5693:Abca13	UTSW	11	9,316,233 (GRCm38)	missense	probably benign	0.29
R5707:Abca13	UTSW	11	9,510,620 (GRCm38)	missense	probably damaging	1.00
R5725:Abca13	UTSW	11	9,577,181 (GRCm38)	missense	probably benign	0.00
R5728:Abca13	UTSW	11	9,570,576 (GRCm38)	missense	probably damaging	1.00
R5738:Abca13	UTSW	11	9,621,917 (GRCm38)	missense	probably damaging	1.00
R5758:Abca13	UTSW	11	9,314,536 (GRCm38)	missense	probably damaging	0.97
R5762:Abca13	UTSW	11	9,581,665 (GRCm38)	missense	probably damaging	1.00
R5771:Abca13	UTSW	11	9,291,411 (GRCm38)	missense	probably damaging	1.00
R5809:Abca13	UTSW	11	9,293,692 (GRCm38)	missense	probably damaging	1.00
R5826:Abca13	UTSW	11	9,682,056 (GRCm38)	missense	probably damaging	0.99
R5831:Abca13	UTSW	11	9,567,777 (GRCm38)	nonsense	probably null
R5834:Abca13	UTSW	11	9,277,974 (GRCm38)	critical splice donor site	probably null
R5902:Abca13	UTSW	11	9,297,177 (GRCm38)	missense	probably damaging	1.00
R5933:Abca13	UTSW	11	9,249,658 (GRCm38)	missense	possibly damaging	0.63
R5945:Abca13	UTSW	11	9,293,398 (GRCm38)	missense	probably benign	0.04
R5969:Abca13	UTSW	11	9,292,214 (GRCm38)	nonsense	probably null
R5985:Abca13	UTSW	11	9,291,628 (GRCm38)	missense	probably benign	0.02
R5998:Abca13	UTSW	11	9,567,708 (GRCm38)	missense	probably damaging	0.97
R6021:Abca13	UTSW	11	9,290,465 (GRCm38)	nonsense	probably null
R6022:Abca13	UTSW	11	9,290,759 (GRCm38)	missense	probably damaging	1.00
R6032:Abca13	UTSW	11	9,297,752 (GRCm38)	missense	possibly damaging	0.52
R6032:Abca13	UTSW	11	9,297,752 (GRCm38)	missense	possibly damaging	0.52
R6105:Abca13	UTSW	11	9,397,812 (GRCm38)	missense	probably damaging	1.00
R6153:Abca13	UTSW	11	9,301,259 (GRCm38)	critical splice acceptor site	probably null
R6162:Abca13	UTSW	11	9,309,047 (GRCm38)	missense	probably damaging	1.00
R6187:Abca13	UTSW	11	9,309,085 (GRCm38)	missense	probably damaging	1.00
R6247:Abca13	UTSW	11	9,403,874 (GRCm38)	missense	probably benign	0.01
R6329:Abca13	UTSW	11	9,277,937 (GRCm38)	missense	probably damaging	1.00
R6352:Abca13	UTSW	11	9,309,139 (GRCm38)	splice site	probably null
R6367:Abca13	UTSW	11	9,216,248 (GRCm38)	missense	possibly damaging	0.85
R6423:Abca13	UTSW	11	9,298,778 (GRCm38)	missense	probably benign	0.01
R6424:Abca13	UTSW	11	9,510,542 (GRCm38)	missense	probably benign
R6456:Abca13	UTSW	11	9,290,474 (GRCm38)	missense	possibly damaging	0.94
R6490:Abca13	UTSW	11	9,298,661 (GRCm38)	missense	probably benign	0.00
R6547:Abca13	UTSW	11	9,274,757 (GRCm38)	missense	probably benign	0.04
R6594:Abca13	UTSW	11	9,294,632 (GRCm38)	missense	possibly damaging	0.52
R6604:Abca13	UTSW	11	9,378,384 (GRCm38)	missense	probably damaging	1.00
R6614:Abca13	UTSW	11	9,294,371 (GRCm38)	missense	probably benign	0.04
R6736:Abca13	UTSW	11	9,465,058 (GRCm38)	missense	probably damaging	1.00
R6742:Abca13	UTSW	11	9,328,168 (GRCm38)	missense	probably damaging	1.00
R6791:Abca13	UTSW	11	9,378,504 (GRCm38)	missense	probably damaging	1.00
R6834:Abca13	UTSW	11	9,275,110 (GRCm38)	missense	possibly damaging	0.48
R6936:Abca13	UTSW	11	9,298,568 (GRCm38)	missense	probably damaging	0.96
R6955:Abca13	UTSW	11	9,294,307 (GRCm38)	missense	probably benign	0.28
R7031:Abca13	UTSW	11	9,621,892 (GRCm38)	missense	probably damaging	1.00
R7065:Abca13	UTSW	11	9,292,595 (GRCm38)	missense	probably benign	0.02
R7067:Abca13	UTSW	11	9,291,845 (GRCm38)	missense	probably benign	0.14
R7070:Abca13	UTSW	11	9,290,701 (GRCm38)	missense	probably benign	0.06
R7094:Abca13	UTSW	11	9,298,610 (GRCm38)	missense	probably damaging	0.96
R7102:Abca13	UTSW	11	9,335,215 (GRCm38)	missense	probably damaging	1.00
R7105:Abca13	UTSW	11	9,397,842 (GRCm38)	missense	probably damaging	1.00
R7131:Abca13	UTSW	11	9,291,893 (GRCm38)	missense	probably benign	0.37
R7155:Abca13	UTSW	11	9,529,010 (GRCm38)	missense	probably benign
R7158:Abca13	UTSW	11	9,273,982 (GRCm38)	missense	probably benign
R7212:Abca13	UTSW	11	9,298,854 (GRCm38)	missense	probably benign	0.04
R7215:Abca13	UTSW	11	9,288,405 (GRCm38)	splice site	probably null
R7228:Abca13	UTSW	11	9,297,653 (GRCm38)	missense	probably benign
R7231:Abca13	UTSW	11	9,294,175 (GRCm38)	missense	probably benign	0.25
R7247:Abca13	UTSW	11	9,290,732 (GRCm38)	missense	probably benign	0.00
R7278:Abca13	UTSW	11	9,291,126 (GRCm38)	missense	possibly damaging	0.56
R7299:Abca13	UTSW	11	9,294,649 (GRCm38)	missense	probably damaging	0.98
R7304:Abca13	UTSW	11	9,297,203 (GRCm38)	missense	probably benign
R7328:Abca13	UTSW	11	9,291,545 (GRCm38)	missense	probably benign	0.14
R7374:Abca13	UTSW	11	9,292,136 (GRCm38)	missense	possibly damaging	0.46
R7376:Abca13	UTSW	11	9,291,118 (GRCm38)	missense	probably benign	0.00
R7384:Abca13	UTSW	11	9,333,257 (GRCm38)	missense	probably damaging	1.00
R7395:Abca13	UTSW	11	9,291,658 (GRCm38)	missense	probably benign	0.01
R7419:Abca13	UTSW	11	9,297,833 (GRCm38)	missense	probably damaging	1.00
R7419:Abca13	UTSW	11	9,276,959 (GRCm38)	missense	probably damaging	1.00
R7421:Abca13	UTSW	11	9,510,463 (GRCm38)	missense	probably benign
R7458:Abca13	UTSW	11	9,290,777 (GRCm38)	missense	possibly damaging	0.94
R7474:Abca13	UTSW	11	9,328,088 (GRCm38)	nonsense	probably null
R7492:Abca13	UTSW	11	9,293,167 (GRCm38)	missense	probably benign	0.08
R7660:Abca13	UTSW	11	9,290,678 (GRCm38)	missense	probably benign	0.00
R7677:Abca13	UTSW	11	9,298,349 (GRCm38)	nonsense	probably null
R7744:Abca13	UTSW	11	9,290,421 (GRCm38)	missense	possibly damaging	0.88
R7790:Abca13	UTSW	11	9,297,915 (GRCm38)	missense	probably damaging	1.00
R7811:Abca13	UTSW	11	9,577,141 (GRCm38)	splice site	probably null
R7831:Abca13	UTSW	11	9,297,404 (GRCm38)	missense	possibly damaging	0.46
R7867:Abca13	UTSW	11	9,262,139 (GRCm38)	critical splice donor site	probably null
R7910:Abca13	UTSW	11	9,581,590 (GRCm38)	missense	probably damaging	1.00
R7964:Abca13	UTSW	11	9,316,146 (GRCm38)	missense	probably benign	0.06
R8037:Abca13	UTSW	11	9,293,904 (GRCm38)	missense	probably damaging	1.00
R8049:Abca13	UTSW	11	9,291,867 (GRCm38)	missense	probably damaging	0.99
R8059:Abca13	UTSW	11	9,373,279 (GRCm38)	missense	probably benign	0.00
R8072:Abca13	UTSW	11	9,294,574 (GRCm38)	missense	probably benign	0.10
R8078:Abca13	UTSW	11	9,301,279 (GRCm38)	missense	probably benign	0.32
R8112:Abca13	UTSW	11	9,314,624 (GRCm38)	missense	probably benign	0.01
R8146:Abca13	UTSW	11	9,397,829 (GRCm38)	missense	probably damaging	1.00
R8164:Abca13	UTSW	11	9,615,799 (GRCm38)	missense	probably damaging	1.00
R8195:Abca13	UTSW	11	9,274,735 (GRCm38)	missense	probably benign	0.00
R8220:Abca13	UTSW	11	9,434,299 (GRCm38)	missense	possibly damaging	0.58
R8235:Abca13	UTSW	11	9,262,077 (GRCm38)	missense	probably damaging	0.99
R8307:Abca13	UTSW	11	9,277,922 (GRCm38)	nonsense	probably null
R8310:Abca13	UTSW	11	9,378,269 (GRCm38)	missense	possibly damaging	0.90
R8315:Abca13	UTSW	11	9,585,502 (GRCm38)	missense	probably benign	0.44
R8315:Abca13	UTSW	11	9,378,460 (GRCm38)	missense	probably null	1.00
R8324:Abca13	UTSW	11	9,290,395 (GRCm38)	missense	probably damaging	1.00
R8375:Abca13	UTSW	11	9,397,841 (GRCm38)	missense	probably damaging	1.00
R8375:Abca13	UTSW	11	9,315,416 (GRCm38)	missense	probably benign	0.00
R8400:Abca13	UTSW	11	9,298,218 (GRCm38)	missense	probably damaging	0.97
R8400:Abca13	UTSW	11	9,293,925 (GRCm38)	missense	probably benign	0.00
R8425:Abca13	UTSW	11	9,314,623 (GRCm38)	missense	possibly damaging	0.92
R8486:Abca13	UTSW	11	9,275,092 (GRCm38)	missense	probably benign	0.00
R8493:Abca13	UTSW	11	9,510,668 (GRCm38)	missense	probably damaging	0.97
R8502:Abca13	UTSW	11	9,269,282 (GRCm38)	missense	probably benign	0.02
R8716:Abca13	UTSW	11	9,293,774 (GRCm38)	missense	probably benign	0.09
R8787:Abca13	UTSW	11	9,275,053 (GRCm38)	missense	possibly damaging	0.92
R8829:Abca13	UTSW	11	9,621,881 (GRCm38)	missense	probably damaging	1.00
R8859:Abca13	UTSW	11	9,378,397 (GRCm38)	missense
R8871:Abca13	UTSW	11	9,298,071 (GRCm38)	missense	probably benign	0.07
R8883:Abca13	UTSW	11	9,333,168 (GRCm38)	missense	probably benign	0.00
R8919:Abca13	UTSW	11	9,291,653 (GRCm38)	missense	possibly damaging	0.84
R8966:Abca13	UTSW	11	9,628,588 (GRCm38)	missense	probably damaging	1.00
R8967:Abca13	UTSW	11	9,292,696 (GRCm38)	missense	probably benign	0.18
R8969:Abca13	UTSW	11	9,277,944 (GRCm38)	missense	probably benign
R8972:Abca13	UTSW	11	9,328,138 (GRCm38)	missense	probably damaging	1.00
R9002:Abca13	UTSW	11	9,291,926 (GRCm38)	missense	possibly damaging	0.94
R9046:Abca13	UTSW	11	9,293,525 (GRCm38)	missense	probably benign	0.04
R9051:Abca13	UTSW	11	9,335,232 (GRCm38)	missense	probably damaging	1.00
R9056:Abca13	UTSW	11	9,464,921 (GRCm38)	missense	probably damaging	1.00
R9061:Abca13	UTSW	11	9,277,847 (GRCm38)	missense	probably benign	0.02
R9072:Abca13	UTSW	11	9,290,834 (GRCm38)	missense	possibly damaging	0.93
R9090:Abca13	UTSW	11	9,291,698 (GRCm38)	missense	probably damaging	0.98
R9127:Abca13	UTSW	11	9,292,080 (GRCm38)	missense	probably benign	0.03
R9164:Abca13	UTSW	11	9,328,157 (GRCm38)	missense	probably damaging	1.00
R9175:Abca13	UTSW	11	9,581,593 (GRCm38)	missense	probably damaging	0.98
R9190:Abca13	UTSW	11	9,291,886 (GRCm38)	missense	probably damaging	0.96
R9244:Abca13	UTSW	11	9,291,577 (GRCm38)	missense	probably benign	0.01
R9255:Abca13	UTSW	11	9,328,213 (GRCm38)	missense	probably damaging	1.00
R9271:Abca13	UTSW	11	9,291,698 (GRCm38)	missense	probably damaging	0.98
R9321:Abca13	UTSW	11	9,510,475 (GRCm38)	missense	probably benign	0.00
R9356:Abca13	UTSW	11	9,256,305 (GRCm38)	missense	probably benign	0.11
R9369:Abca13	UTSW	11	9,378,444 (GRCm38)	missense	probably damaging	1.00
R9423:Abca13	UTSW	11	9,290,395 (GRCm38)	missense	probably damaging	1.00
R9432:Abca13	UTSW	11	9,294,559 (GRCm38)	missense	probably benign	0.00
R9455:Abca13	UTSW	11	9,403,897 (GRCm38)	missense	probably damaging	1.00
R9486:Abca13	UTSW	11	9,290,621 (GRCm38)	missense	possibly damaging	0.88
R9492:Abca13	UTSW	11	9,293,667 (GRCm38)	nonsense	probably null
R9511:Abca13	UTSW	11	9,328,130 (GRCm38)	missense	probably benign	0.16
R9545:Abca13	UTSW	11	9,466,538 (GRCm38)	missense	probably damaging	1.00
R9566:Abca13	UTSW	11	9,464,927 (GRCm38)	missense	probably damaging	1.00
R9609:Abca13	UTSW	11	9,258,549 (GRCm38)	missense	probably damaging	1.00
R9616:Abca13	UTSW	11	9,290,501 (GRCm38)	missense	probably benign	0.00
R9651:Abca13	UTSW	11	9,585,484 (GRCm38)	missense	probably benign
R9651:Abca13	UTSW	11	9,293,741 (GRCm38)	missense	probably benign	0.31
R9653:Abca13	UTSW	11	9,293,741 (GRCm38)	missense	probably benign	0.31
R9657:Abca13	UTSW	11	9,293,379 (GRCm38)	missense	probably benign	0.35
R9684:Abca13	UTSW	11	9,333,307 (GRCm38)	missense	probably damaging	1.00
X0013:Abca13	UTSW	11	9,273,899 (GRCm38)	missense	probably benign	0.02
X0057:Abca13	UTSW	11	9,294,744 (GRCm38)	missense	probably damaging	0.96
X0066:Abca13	UTSW	11	9,267,565 (GRCm38)	missense	probably damaging	0.96
Z1088:Abca13	UTSW	11	9,294,687 (GRCm38)	missense	probably damaging	0.99
Z1176:Abca13	UTSW	11	9,267,461 (GRCm38)	missense	probably damaging	1.00
Z1176:Abca13	UTSW	11	9,251,376 (GRCm38)	missense	possibly damaging	0.88
Z1176:Abca13	UTSW	11	9,335,182 (GRCm38)	missense	probably damaging	1.00
Z1176:Abca13	UTSW	11	9,335,181 (GRCm38)	missense	probably damaging	1.00
Z1176:Abca13	UTSW	11	9,294,342 (GRCm38)	missense	probably benign	0.01
Z1177:Abca13	UTSW	11	9,314,545 (GRCm38)	frame shift	probably null

Predicted Primers

PCR Primer
(F):5'- AGTGGCGAGTGAATGCTTC -3'
(R):5'- TGAAGGCCATCCCAGTCATG -3'

Sequencing Primer
(F):5'- ATTATTCAGGAAACGAGGGGTCTTCC -3'
(R):5'- CAGTCATGGAAGTTATTCTCCTGAG -3'

Posted On

2019-11-26