Mutagenetix > Incidental Mutation

Incidental Mutation 'R7803:Tenm2'

600627

Institutional Source

Beutler Lab

Gene Symbol

Tenm2

Ensembl Gene

ENSMUSG00000049336

Gene Name

teneurin transmembrane protein 2

Synonyms

2610040L17Rik, 9330187F13Rik, D3Bwg1534e, Ten-m2, Odz2

MMRRC Submission

045858-MU

Accession Numbers

Essential gene?

Possibly essential (E-score: 0.514) question?

Stock #

R7803 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

36006656-37235964 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 36047116 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Serine to Threonine at position 1578 (S1578T)

Ref Sequence

ENSEMBL: ENSMUSP00000052014 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000057207] [ENSMUST00000102801] [ENSMUST00000163524]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000057207
AA Change: S1578T

PolyPhen 2 Score 0.976 (Sensitivity: 0.76; Specificity: 0.96)

SMART Domains

Protein: ENSMUSP00000052014
Gene: ENSMUSG00000049336
AA Change: S1578T

Domain	Start	End	E-Value	Type
Pfam:Ten_N	10	374	4.9e-177	PFAM
transmembrane domain	375	397	N/A	INTRINSIC
EGF	575	603	5.62e0	SMART
EGF_like	606	634	4.93e1	SMART
EGF	639	668	1.76e1	SMART
EGF	671	700	1.43e-1	SMART
EGF	705	735	1.2e1	SMART
EGF	738	766	9.63e0	SMART
EGF	769	797	1.25e1	SMART
EGF	800	832	1.4e0	SMART
low complexity region	1459	1475	N/A	INTRINSIC
low complexity region	2219	2230	N/A	INTRINSIC
Pfam:Tox-GHH	2681	2758	1.4e-34	PFAM

Predicted Effect

probably damaging
Transcript: ENSMUST00000102801
AA Change: S1577T

PolyPhen 2 Score 0.980 (Sensitivity: 0.75; Specificity: 0.96)

SMART Domains

Protein: ENSMUSP00000099865
Gene: ENSMUSG00000049336
AA Change: S1577T

Domain	Start	End	E-Value	Type
Pfam:Ten_N	9	374	2e-186	PFAM
transmembrane domain	375	397	N/A	INTRINSIC
EGF	575	603	5.62e0	SMART
EGF_like	606	634	4.93e1	SMART
EGF	639	668	1.76e1	SMART
EGF	671	700	1.43e-1	SMART
EGF	705	735	1.2e1	SMART
EGF	737	765	9.63e0	SMART
EGF	768	796	1.25e1	SMART
EGF	799	831	1.4e0	SMART
low complexity region	1458	1474	N/A	INTRINSIC
low complexity region	2218	2229	N/A	INTRINSIC
Pfam:Tox-GHH	2679	2757	2e-34	PFAM

Predicted Effect

probably damaging
Transcript: ENSMUST00000163524
AA Change: S1577T

PolyPhen 2 Score 0.980 (Sensitivity: 0.75; Specificity: 0.96)

SMART Domains

Protein: ENSMUSP00000129951
Gene: ENSMUSG00000049336
AA Change: S1577T

Domain	Start	End	E-Value	Type
Pfam:Ten_N	9	374	2e-186	PFAM
transmembrane domain	375	397	N/A	INTRINSIC
EGF	575	603	5.62e0	SMART
EGF_like	606	634	4.93e1	SMART
EGF	639	668	1.76e1	SMART
EGF	671	700	1.43e-1	SMART
EGF	705	735	1.2e1	SMART
EGF	737	765	9.63e0	SMART
EGF	768	796	1.25e1	SMART
EGF	799	831	1.4e0	SMART
low complexity region	1458	1474	N/A	INTRINSIC
low complexity region	2218	2229	N/A	INTRINSIC
Pfam:Tox-GHH	2679	2757	2e-34	PFAM

Coding Region Coverage

1x: 100.0%
3x: 100.0%
10x: 99.8%
20x: 99.4%

Validation Efficiency

98% (49/50)

MGI Phenotype

PHENOTYPE: Mice homozygous for a null allele show abnormalities in the laterality and mapping of ipsilateral retinal projections that lead to loss of ipsilateral drive, defects in binocular vision, and impaired performance on a visual discrimination task. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 57 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Acta2	C	A	19: 34,243,418 (GRCm38)	A297S	probably benign	Het
Ada	A	G	2: 163,735,368 (GRCm38)	Y67H	probably benign	Het
Adcy9	A	G	16: 4,304,380 (GRCm38)	I839T	probably benign	Het
Arg1	C	T	10: 24,916,791 (GRCm38)	V182I	possibly damaging	Het
Cbx7	G	A	15: 79,933,823 (GRCm38)	T26M	unknown	Het
Ceacam5	A	G	7: 17,759,392 (GRCm38)	Y780C	probably damaging	Het
Ces2h	A	G	8: 105,018,400 (GRCm38)	M389V	probably benign	Het
Chst11	A	T	10: 83,191,186 (GRCm38)	E149V	possibly damaging	Het
Clstn1	T	C	4: 149,631,871 (GRCm38)	W265R	probably damaging	Het
Col4a4	A	G	1: 82,489,698 (GRCm38)		probably null	Het
Csrp3	T	G	7: 48,833,797 (GRCm38)	K119T	probably benign	Het
Ddx39a	T	C	8: 83,719,600 (GRCm38)		probably null	Het
Ddx41	A	G	13: 55,531,921 (GRCm38)	I437T	probably damaging	Het
Eif1ad4	T	A	12: 87,895,499 (GRCm38)	C44S	probably benign	Het
Fbln5	A	T	12: 101,761,818 (GRCm38)	D282E	probably damaging	Het
Folh1	G	A	7: 86,726,098 (GRCm38)	T527I	probably damaging	Het
Gch1	T	A	14: 47,188,961 (GRCm38)	T103S	probably benign	Het
Gpr149	A	G	3: 62,530,715 (GRCm38)	S674P	probably damaging	Het
Hecw1	G	T	13: 14,234,342 (GRCm38)	R1127S	probably benign	Het
Hmcn1	A	T	1: 150,770,279 (GRCm38)	C723S	probably benign	Het
Impg2	T	C	16: 56,267,150 (GRCm38)	S1111P	probably damaging	Het
Insl3	T	C	8: 71,689,340 (GRCm38)	L28P	probably damaging	Het
Kifc1	T	C	17: 33,884,740 (GRCm38)	D203G	probably benign	Het
Kmt2d	A	T	15: 98,862,923 (GRCm38)	S849T	unknown	Het
Krt33b	A	G	11: 100,025,258 (GRCm38)		probably null	Het
Lpin3	A	G	2: 160,895,390 (GRCm38)	D119G	possibly damaging	Het
Maml2	AGC	AGCCGC	9: 13,621,254 (GRCm38)		probably benign	Het
Maml2	AGC	AGCCGC	9: 13,621,275 (GRCm38)		probably benign	Het
Maml2	GCA	GCACCA	9: 13,621,276 (GRCm38)		probably benign	Het
Nsun7	T	A	5: 66,276,541 (GRCm38)	L178*	probably null	Het
Or6c1b	A	G	10: 129,436,931 (GRCm38)	N40D	probably damaging	Het
Or6c205	A	T	10: 129,250,995 (GRCm38)	I154F	probably benign	Het
Or8g55	A	T	9: 39,874,082 (GRCm38)	D269V	probably benign	Het
Orc6	T	A	8: 85,303,408 (GRCm38)	S136T	possibly damaging	Het
Peg10	CATCAGGATCCCCATCAGGATGCACATCAGGATCCACATCAGGATGCACATCAGGATC	CATC	6: 4,756,431 (GRCm38)		probably benign	Het
Plxnc1	A	G	10: 94,943,515 (GRCm38)		probably null	Het
Prkdc	G	A	16: 15,806,096 (GRCm38)	D3308N	probably null	Het
Rtkn2	G	A	10: 67,979,813 (GRCm38)		probably null	Het
Sele	T	C	1: 164,050,694 (GRCm38)	S201P	possibly damaging	Het
Shq1	A	G	6: 100,671,045 (GRCm38)	F6S	probably damaging	Het
Sparc	A	T	11: 55,409,971 (GRCm38)	I5N	probably damaging	Het
Spata31e3	A	G	13: 50,246,190 (GRCm38)	V700A	probably benign	Het
Srm	T	C	4: 148,593,945 (GRCm38)	I238T	probably damaging	Het
Stx2	C	A	5: 128,993,563 (GRCm38)	E97*	probably null	Het
Sugp2	C	T	8: 70,252,072 (GRCm38)	P753L	probably benign	Het
Tff3	T	C	17: 31,129,570 (GRCm38)	T3A	probably benign	Het
Tmem38a	C	T	8: 72,572,120 (GRCm38)	A6V	probably benign	Het
Trbv16	G	A	6: 41,151,995 (GRCm38)	A38T	not run	Het
Trim30a	G	A	7: 104,411,397 (GRCm38)	Q391*	probably null	Het
Ttn	T	G	2: 76,776,371 (GRCm38)	Y18065S	probably damaging	Het
Ubr5	G	A	15: 37,979,832 (GRCm38)	A2434V	probably null	Het
Vmn2r24	T	A	6: 123,780,479 (GRCm38)	M102K	probably benign	Het
Vmn2r69	G	T	7: 85,407,116 (GRCm38)	H605N	probably benign	Het
Washc1	T	A	17: 66,119,060 (GRCm38)	M451K	possibly damaging	Het
Washc3	G	T	10: 88,216,075 (GRCm38)		probably null	Het
Washc5	A	T	15: 59,368,459 (GRCm38)	Y112N	probably damaging	Het
Zbtb40	T	A	4: 137,017,327 (GRCm38)	T261S	probably benign	Het

Other mutations in Tenm2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00161:Tenm2	APN	11	36,206,899 (GRCm38)	splice site	probably benign
IGL00834:Tenm2	APN	11	36,024,258 (GRCm38)	missense	probably damaging	1.00
IGL00911:Tenm2	APN	11	36,008,733 (GRCm38)	nonsense	probably null
IGL00937:Tenm2	APN	11	36,024,623 (GRCm38)	missense	probably damaging	1.00
IGL01154:Tenm2	APN	11	36,041,544 (GRCm38)	missense	probably damaging	1.00
IGL01313:Tenm2	APN	11	36,024,248 (GRCm38)	missense	probably damaging	0.98
IGL01346:Tenm2	APN	11	36,027,405 (GRCm38)	nonsense	probably null
IGL01539:Tenm2	APN	11	36,106,827 (GRCm38)	missense	possibly damaging	0.89
IGL01629:Tenm2	APN	11	36,864,884 (GRCm38)	missense	probably damaging	0.98
IGL01780:Tenm2	APN	11	36,046,941 (GRCm38)	missense	probably benign
IGL01821:Tenm2	APN	11	36,023,883 (GRCm38)	missense	probably damaging	0.98
IGL01988:Tenm2	APN	11	36,027,251 (GRCm38)	missense	probably damaging	1.00
IGL02002:Tenm2	APN	11	36,207,095 (GRCm38)	missense	probably benign
IGL02449:Tenm2	APN	11	36,023,622 (GRCm38)	missense	probably damaging	0.99
IGL02505:Tenm2	APN	11	36,051,916 (GRCm38)	nonsense	probably null
IGL02649:Tenm2	APN	11	36,207,085 (GRCm38)	missense	possibly damaging	0.85
IGL02688:Tenm2	APN	11	36,068,458 (GRCm38)	missense	probably benign	0.05
IGL02801:Tenm2	APN	11	36,047,030 (GRCm38)	nonsense	probably null
IGL02928:Tenm2	APN	11	36,027,170 (GRCm38)	missense	possibly damaging	0.69
IGL02940:Tenm2	APN	11	36,041,644 (GRCm38)	missense	probably damaging	1.00
IGL03202:Tenm2	APN	11	36,024,548 (GRCm38)	missense	probably damaging	1.00
IGL03213:Tenm2	APN	11	36,023,330 (GRCm38)	missense	probably benign	0.05
IGL03276:Tenm2	APN	11	36,072,776 (GRCm38)	missense	possibly damaging	0.95
IGL03296:Tenm2	APN	11	36,052,025 (GRCm38)	splice site	probably null
IGL03381:Tenm2	APN	11	36,068,411 (GRCm38)	missense	probably benign	0.01
IGL03398:Tenm2	APN	11	36,024,543 (GRCm38)	missense	probably damaging	1.00
browser	UTSW	11	36,046,765 (GRCm38)	critical splice donor site	probably null
mosaic	UTSW	11	36,063,775 (GRCm38)	critical splice donor site	probably null
IGL02799:Tenm2	UTSW	11	36,273,408 (GRCm38)	missense	probably damaging	1.00
PIT4260001:Tenm2	UTSW	11	36,163,730 (GRCm38)	missense	probably damaging	1.00
PIT4382001:Tenm2	UTSW	11	36,063,902 (GRCm38)	missense	probably damaging	0.99
R0004:Tenm2	UTSW	11	36,023,357 (GRCm38)	missense	probably damaging	1.00
R0420:Tenm2	UTSW	11	36,207,124 (GRCm38)	splice site	probably benign
R0537:Tenm2	UTSW	11	36,163,730 (GRCm38)	missense	probably damaging	1.00
R0599:Tenm2	UTSW	11	36,024,780 (GRCm38)	missense	possibly damaging	0.93
R0636:Tenm2	UTSW	11	36,943,976 (GRCm38)	missense	probably damaging	1.00
R0693:Tenm2	UTSW	11	36,024,809 (GRCm38)	missense	probably damaging	1.00
R0991:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R0992:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1167:Tenm2	UTSW	11	36,864,684 (GRCm38)	missense	probably benign	0.30
R1177:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1178:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1179:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1180:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1181:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1193:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1194:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1195:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1195:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1195:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1259:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1265:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1267:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1268:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1269:Tenm2	UTSW	11	36,008,358 (GRCm38)	missense	possibly damaging	0.64
R1270:Tenm2	UTSW	11	36,041,659 (GRCm38)	missense	probably damaging	1.00
R1272:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1273:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1311:Tenm2	UTSW	11	36,068,594 (GRCm38)	splice site	probably benign
R1374:Tenm2	UTSW	11	36,008,454 (GRCm38)	missense	probably benign	0.00
R1542:Tenm2	UTSW	11	36,300,220 (GRCm38)	missense	probably damaging	0.99
R1573:Tenm2	UTSW	11	36,047,069 (GRCm38)	missense	probably damaging	1.00
R1579:Tenm2	UTSW	11	36,106,783 (GRCm38)	missense	probably damaging	1.00
R1697:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1722:Tenm2	UTSW	11	36,008,103 (GRCm38)	missense	probably damaging	1.00
R1756:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1793:Tenm2	UTSW	11	36,023,382 (GRCm38)	missense	probably damaging	0.99
R1950:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1954:Tenm2	UTSW	11	36,047,547 (GRCm38)	missense	possibly damaging	0.87
R2025:Tenm2	UTSW	11	36,047,264 (GRCm38)	nonsense	probably null
R2117:Tenm2	UTSW	11	36,024,854 (GRCm38)	missense	probably damaging	1.00
R2244:Tenm2	UTSW	11	36,864,862 (GRCm38)	missense	probably damaging	0.98
R2298:Tenm2	UTSW	11	36,046,777 (GRCm38)	missense	possibly damaging	0.62
R2432:Tenm2	UTSW	11	36,027,191 (GRCm38)	missense	probably damaging	1.00
R3014:Tenm2	UTSW	11	36,023,973 (GRCm38)	missense	probably damaging	1.00
R3115:Tenm2	UTSW	11	36,023,366 (GRCm38)	missense	probably damaging	1.00
R3684:Tenm2	UTSW	11	36,051,817 (GRCm38)	missense	probably benign	0.00
R3685:Tenm2	UTSW	11	36,051,817 (GRCm38)	missense	probably benign	0.00
R3705:Tenm2	UTSW	11	36,068,326 (GRCm38)	missense	probably damaging	0.97
R3820:Tenm2	UTSW	11	36,024,320 (GRCm38)	missense	probably damaging	0.98
R3821:Tenm2	UTSW	11	36,024,320 (GRCm38)	missense	probably damaging	0.98
R3822:Tenm2	UTSW	11	36,024,320 (GRCm38)	missense	probably damaging	0.98
R3844:Tenm2	UTSW	11	36,047,538 (GRCm38)	missense	probably damaging	0.98
R3878:Tenm2	UTSW	11	36,139,574 (GRCm38)	critical splice donor site	probably null
R4019:Tenm2	UTSW	11	36,047,074 (GRCm38)	missense	probably benign	0.04
R4062:Tenm2	UTSW	11	36,008,655 (GRCm38)	missense	probably damaging	1.00
R4367:Tenm2	UTSW	11	36,027,398 (GRCm38)	missense	probably benign
R4395:Tenm2	UTSW	11	36,024,624 (GRCm38)	missense	probably benign	0.23
R4508:Tenm2	UTSW	11	36,008,345 (GRCm38)	missense	possibly damaging	0.82
R4534:Tenm2	UTSW	11	36,063,104 (GRCm38)	missense	possibly damaging	0.64
R4539:Tenm2	UTSW	11	36,046,780 (GRCm38)	missense	probably damaging	1.00
R4644:Tenm2	UTSW	11	36,047,136 (GRCm38)	missense	probably benign	0.00
R4661:Tenm2	UTSW	11	36,024,448 (GRCm38)	missense	probably damaging	0.99
R4669:Tenm2	UTSW	11	36,010,487 (GRCm38)	missense	probably damaging	1.00
R4687:Tenm2	UTSW	11	36,049,097 (GRCm38)	missense	probably benign
R4711:Tenm2	UTSW	11	36,300,212 (GRCm38)	missense	probably damaging	0.98
R4816:Tenm2	UTSW	11	36,027,290 (GRCm38)	missense	probably damaging	1.00
R4843:Tenm2	UTSW	11	36,024,020 (GRCm38)	missense	probably damaging	1.00
R4850:Tenm2	UTSW	11	36,023,488 (GRCm38)	nonsense	probably null
R4870:Tenm2	UTSW	11	36,078,569 (GRCm38)	missense	probably damaging	1.00
R5058:Tenm2	UTSW	11	36,207,080 (GRCm38)	missense	possibly damaging	0.80
R5071:Tenm2	UTSW	11	36,068,381 (GRCm38)	missense	probably damaging	0.99
R5073:Tenm2	UTSW	11	36,068,381 (GRCm38)	missense	probably damaging	0.99
R5074:Tenm2	UTSW	11	36,068,381 (GRCm38)	missense	probably damaging	0.99
R5081:Tenm2	UTSW	11	36,024,633 (GRCm38)	missense	possibly damaging	0.95
R5093:Tenm2	UTSW	11	36,944,162 (GRCm38)	missense	probably damaging	1.00
R5170:Tenm2	UTSW	11	36,024,806 (GRCm38)	missense	probably damaging	0.98
R5253:Tenm2	UTSW	11	36,047,201 (GRCm38)	nonsense	probably null
R5343:Tenm2	UTSW	11	36,069,503 (GRCm38)	missense	probably benign	0.00
R5493:Tenm2	UTSW	11	36,864,676 (GRCm38)	missense	probably benign	0.01
R5600:Tenm2	UTSW	11	36,163,714 (GRCm38)	splice site	probably null
R5677:Tenm2	UTSW	11	36,141,683 (GRCm38)	missense	probably damaging	0.98
R5703:Tenm2	UTSW	11	36,023,799 (GRCm38)	missense	probably benign	0.34
R5707:Tenm2	UTSW	11	36,047,182 (GRCm38)	missense	possibly damaging	0.79
R6026:Tenm2	UTSW	11	36,072,729 (GRCm38)	critical splice donor site	probably null
R6063:Tenm2	UTSW	11	36,163,717 (GRCm38)	critical splice donor site	probably null
R6086:Tenm2	UTSW	11	36,008,646 (GRCm38)	missense	possibly damaging	0.64
R6151:Tenm2	UTSW	11	36,008,783 (GRCm38)	missense	probably damaging	1.00
R6169:Tenm2	UTSW	11	36,139,690 (GRCm38)	missense	probably damaging	0.99
R6193:Tenm2	UTSW	11	36,046,794 (GRCm38)	missense	probably damaging	1.00
R6405:Tenm2	UTSW	11	36,864,859 (GRCm38)	missense	probably benign	0.44
R6477:Tenm2	UTSW	11	36,010,507 (GRCm38)	critical splice acceptor site	probably null
R6607:Tenm2	UTSW	11	36,063,775 (GRCm38)	critical splice donor site	probably null
R6668:Tenm2	UTSW	11	36,046,765 (GRCm38)	critical splice donor site	probably null
R6825:Tenm2	UTSW	11	36,046,884 (GRCm38)	missense	probably benign	0.02
R6885:Tenm2	UTSW	11	36,023,580 (GRCm38)	missense	possibly damaging	0.95
R7017:Tenm2	UTSW	11	36,171,409 (GRCm38)	missense	probably damaging	0.98
R7115:Tenm2	UTSW	11	36,163,817 (GRCm38)	missense	probably damaging	0.99
R7153:Tenm2	UTSW	11	36,024,182 (GRCm38)	missense	probably damaging	0.98
R7173:Tenm2	UTSW	11	36,041,551 (GRCm38)	missense	probably damaging	0.99
R7199:Tenm2	UTSW	11	36,171,436 (GRCm38)	missense	probably damaging	1.00
R7205:Tenm2	UTSW	11	36,049,129 (GRCm38)	missense	probably damaging	0.99
R7250:Tenm2	UTSW	11	36,072,798 (GRCm38)	missense	probably damaging	1.00
R7290:Tenm2	UTSW	11	36,023,471 (GRCm38)	missense	probably damaging	1.00
R7366:Tenm2	UTSW	11	36,069,414 (GRCm38)	missense	probably benign	0.09
R7432:Tenm2	UTSW	11	36,864,941 (GRCm38)	missense	probably benign
R7504:Tenm2	UTSW	11	36,139,743 (GRCm38)	missense	probably damaging	1.00
R7513:Tenm2	UTSW	11	36,051,900 (GRCm38)	missense	probably benign	0.34
R7523:Tenm2	UTSW	11	36,078,581 (GRCm38)	splice site	probably null
R7527:Tenm2	UTSW	11	36,206,976 (GRCm38)	missense	probably damaging	1.00
R7648:Tenm2	UTSW	11	36,106,736 (GRCm38)	missense	probably damaging	1.00
R7653:Tenm2	UTSW	11	36,047,347 (GRCm38)	missense	probably benign	0.09
R7717:Tenm2	UTSW	11	36,864,935 (GRCm38)	missense	probably damaging	0.97
R7739:Tenm2	UTSW	11	36,069,561 (GRCm38)	missense	possibly damaging	0.50
R7762:Tenm2	UTSW	11	36,023,306 (GRCm38)	missense	possibly damaging	0.74
R7786:Tenm2	UTSW	11	36,010,449 (GRCm38)	missense	probably damaging	0.99
R7834:Tenm2	UTSW	11	36,024,854 (GRCm38)	missense	probably damaging	1.00
R7838:Tenm2	UTSW	11	36,106,799 (GRCm38)	missense	probably benign	0.02
R8073:Tenm2	UTSW	11	36,139,644 (GRCm38)	missense	possibly damaging	0.56
R8076:Tenm2	UTSW	11	36,027,221 (GRCm38)	missense	probably benign	0.23
R8109:Tenm2	UTSW	11	36,008,310 (GRCm38)	missense	probably benign
R8306:Tenm2	UTSW	11	36,069,369 (GRCm38)	missense	possibly damaging	0.52
R8352:Tenm2	UTSW	11	36,023,601 (GRCm38)	missense	probably damaging	0.98
R8452:Tenm2	UTSW	11	36,023,601 (GRCm38)	missense	probably damaging	0.98
R8864:Tenm2	UTSW	11	36,027,195 (GRCm38)	missense	possibly damaging	0.95
R8880:Tenm2	UTSW	11	36,051,961 (GRCm38)	missense	probably damaging	0.99
R8943:Tenm2	UTSW	11	36,944,034 (GRCm38)	missense	probably damaging	0.98
R8969:Tenm2	UTSW	11	36,051,861 (GRCm38)	missense	probably damaging	0.99
R9168:Tenm2	UTSW	11	36,039,895 (GRCm38)	missense	probably damaging	1.00
R9279:Tenm2	UTSW	11	36,068,476 (GRCm38)	missense	probably benign	0.00
R9294:Tenm2	UTSW	11	36,024,500 (GRCm38)	missense	probably damaging	0.98
R9320:Tenm2	UTSW	11	36,023,647 (GRCm38)	missense	probably damaging	0.99
R9373:Tenm2	UTSW	11	36,039,886 (GRCm38)	missense	probably damaging	1.00
R9408:Tenm2	UTSW	11	36,069,419 (GRCm38)	missense	probably damaging	1.00
R9410:Tenm2	UTSW	11	36,141,569 (GRCm38)	missense	probably damaging	0.99
R9454:Tenm2	UTSW	11	36,221,459 (GRCm38)	missense	probably benign
R9489:Tenm2	UTSW	11	36,943,964 (GRCm38)	missense	probably damaging	0.99
R9711:Tenm2	UTSW	11	36,024,514 (GRCm38)	missense	probably damaging	0.99
RF021:Tenm2	UTSW	11	36,024,203 (GRCm38)	missense	possibly damaging	0.95
X0018:Tenm2	UTSW	11	36,024,200 (GRCm38)	missense	probably damaging	1.00
X0063:Tenm2	UTSW	11	36,024,730 (GRCm38)	missense	probably benign
Z1088:Tenm2	UTSW	11	36,273,267 (GRCm38)	missense	probably damaging	1.00
Z1177:Tenm2	UTSW	11	36,385,130 (GRCm38)	missense	probably benign	0.01
Z1177:Tenm2	UTSW	11	36,300,335 (GRCm38)	missense	probably damaging	0.98
Z1177:Tenm2	UTSW	11	36,008,234 (GRCm38)	missense	possibly damaging	0.95

Predicted Primers

PCR Primer
(F):5'- CCCACGGTAAGGGTGATAATCTG -3'
(R):5'- ATCTGCTACTCGGGAGATGAC -3'

Sequencing Primer
(F):5'- TCTGATTATCAGGCATGAGCAG -3'
(R):5'- TACTCGGGAGATGACGCTTAC -3'

Posted On

2019-11-26