Incidental Mutation 'R7810:Flg2'
| ID |
601063 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Flg2
|
| Ensembl Gene |
ENSMUSG00000049133 |
| Gene Name |
filaggrin family member 2 |
| Synonyms |
EG229574 |
| MMRRC Submission |
045865-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.126)
|
| Stock # |
R7810 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
3 |
| Chromosomal Location |
93104585-93128698 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 93107548 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Threonine
at position 11
(I11T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000096482
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000098884]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000098884
AA Change: I11T
PolyPhen 2
Score 0.703 (Sensitivity: 0.86; Specificity: 0.92)
|
| SMART Domains |
Protein: ENSMUSP00000096482
Gene: ENSMUSG00000049133
AA Change: I11T
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:S_100
|
4 |
46 |
1.2e-17 |
PFAM |
|
low complexity region
|
58 |
70 |
N/A |
INTRINSIC |
|
low complexity region
|
110 |
121 |
N/A |
INTRINSIC |
|
low complexity region
|
131 |
146 |
N/A |
INTRINSIC |
|
low complexity region
|
207 |
223 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
230 |
347 |
7.36e-7 |
PROSPERO |
|
internal_repeat_2
|
349 |
466 |
7.36e-7 |
PROSPERO |
|
internal_repeat_3
|
366 |
392 |
6.93e-6 |
PROSPERO |
|
internal_repeat_6
|
419 |
471 |
4.17e-5 |
PROSPERO |
|
low complexity region
|
474 |
550 |
N/A |
INTRINSIC |
|
low complexity region
|
567 |
589 |
N/A |
INTRINSIC |
|
low complexity region
|
593 |
679 |
N/A |
INTRINSIC |
|
low complexity region
|
680 |
705 |
N/A |
INTRINSIC |
|
low complexity region
|
719 |
748 |
N/A |
INTRINSIC |
|
low complexity region
|
749 |
768 |
N/A |
INTRINSIC |
|
low complexity region
|
772 |
800 |
N/A |
INTRINSIC |
|
internal_repeat_5
|
804 |
825 |
4.17e-5 |
PROSPERO |
|
internal_repeat_3
|
810 |
836 |
6.93e-6 |
PROSPERO |
|
low complexity region
|
846 |
860 |
N/A |
INTRINSIC |
|
low complexity region
|
863 |
885 |
N/A |
INTRINSIC |
|
internal_repeat_5
|
895 |
919 |
4.17e-5 |
PROSPERO |
|
internal_repeat_4
|
899 |
939 |
1.7e-5 |
PROSPERO |
|
internal_repeat_1
|
944 |
1461 |
8.08e-127 |
PROSPERO |
|
internal_repeat_6
|
1335 |
1386 |
4.17e-5 |
PROSPERO |
|
low complexity region
|
1465 |
1485 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
1486 |
2009 |
8.08e-127 |
PROSPERO |
|
internal_repeat_4
|
2123 |
2173 |
1.7e-5 |
PROSPERO |
|
| Meta Mutation Damage Score |
0.1712 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.0%
|
| Validation Efficiency |
99% (91/92) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 94 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adam34 |
T |
C |
8: 44,105,045 (GRCm39) |
E200G |
probably benign |
Het |
| Ankfy1 |
C |
T |
11: 72,645,281 (GRCm39) |
Q787* |
probably null |
Het |
| Birc6 |
T |
A |
17: 74,855,815 (GRCm39) |
H208Q |
probably damaging |
Het |
| Brsk2 |
T |
A |
7: 141,539,157 (GRCm39) |
|
probably null |
Het |
| Cabp5 |
T |
A |
7: 13,132,263 (GRCm39) |
F11I |
possibly damaging |
Het |
| Ccdc88a |
T |
C |
11: 29,435,964 (GRCm39) |
Y1296H |
probably damaging |
Het |
| Ccdc88b |
A |
G |
19: 6,826,454 (GRCm39) |
V1087A |
probably benign |
Het |
| Cct3 |
C |
T |
3: 88,228,442 (GRCm39) |
T508I |
probably damaging |
Het |
| Ceacam9 |
T |
A |
7: 16,457,658 (GRCm39) |
M57K |
possibly damaging |
Het |
| Ces1f |
T |
C |
8: 93,983,546 (GRCm39) |
E487G |
probably damaging |
Het |
| Chd5 |
A |
G |
4: 152,443,032 (GRCm39) |
K278E |
probably damaging |
Het |
| Cntnap3 |
T |
A |
13: 64,941,122 (GRCm39) |
H286L |
possibly damaging |
Het |
| Dnai7 |
T |
G |
6: 145,140,312 (GRCm39) |
D163A |
probably benign |
Het |
| Efr3a |
G |
T |
15: 65,659,022 (GRCm39) |
|
probably benign |
Het |
| Fastkd2 |
T |
A |
1: 63,770,851 (GRCm39) |
I69N |
possibly damaging |
Het |
| Folr2 |
T |
C |
7: 101,490,102 (GRCm39) |
M84V |
possibly damaging |
Het |
| Galnt12 |
T |
C |
4: 47,113,786 (GRCm39) |
F360S |
probably damaging |
Het |
| Galr2 |
T |
C |
11: 116,173,946 (GRCm39) |
V192A |
probably benign |
Het |
| Gas6 |
A |
T |
8: 13,516,809 (GRCm39) |
I563N |
probably damaging |
Het |
| Gbe1 |
T |
C |
16: 70,324,085 (GRCm39) |
F567L |
possibly damaging |
Het |
| Gm12695 |
G |
A |
4: 96,619,608 (GRCm39) |
H423Y |
probably damaging |
Het |
| Gm6902 |
T |
C |
7: 22,973,243 (GRCm39) |
T95A |
probably benign |
Het |
| Gpr155 |
G |
T |
2: 73,212,296 (GRCm39) |
A109D |
probably damaging |
Het |
| Hsdl1 |
T |
C |
8: 120,294,711 (GRCm39) |
D5G |
probably damaging |
Het |
| Hyal1 |
C |
T |
9: 107,455,628 (GRCm39) |
P313S |
probably damaging |
Het |
| Igfn1 |
G |
A |
1: 135,902,527 (GRCm39) |
T390M |
probably damaging |
Het |
| Irx1 |
C |
A |
13: 72,107,917 (GRCm39) |
R255L |
probably benign |
Het |
| Itga2 |
T |
A |
13: 115,002,715 (GRCm39) |
T592S |
probably benign |
Het |
| Kit |
C |
A |
5: 75,769,982 (GRCm39) |
S131R |
probably benign |
Het |
| Map1b |
T |
C |
13: 99,568,390 (GRCm39) |
T1444A |
unknown |
Het |
| Mapk8ip1 |
C |
T |
2: 92,219,496 (GRCm39) |
E112K |
probably benign |
Het |
| Marveld3 |
T |
C |
8: 110,681,266 (GRCm39) |
I210V |
probably damaging |
Het |
| Masp1 |
T |
A |
16: 23,295,068 (GRCm39) |
I398L |
probably benign |
Het |
| Mmrn1 |
T |
C |
6: 60,953,309 (GRCm39) |
I530T |
probably benign |
Het |
| Mtss2 |
A |
G |
8: 111,452,833 (GRCm39) |
Y26C |
probably damaging |
Het |
| Myo5a |
T |
A |
9: 75,067,747 (GRCm39) |
S600R |
probably benign |
Het |
| Myo5a |
A |
G |
9: 75,076,292 (GRCm39) |
I836V |
probably benign |
Het |
| Naaladl1 |
A |
G |
19: 6,159,694 (GRCm39) |
D375G |
probably damaging |
Het |
| Napepld |
T |
A |
5: 21,888,263 (GRCm39) |
D62V |
possibly damaging |
Het |
| Nedd9 |
A |
C |
13: 41,465,483 (GRCm39) |
I719S |
possibly damaging |
Het |
| Nes |
T |
A |
3: 87,882,923 (GRCm39) |
M394K |
probably benign |
Het |
| Nlrc5 |
A |
T |
8: 95,231,772 (GRCm39) |
Y1288F |
possibly damaging |
Het |
| Nlrp14 |
T |
A |
7: 106,791,782 (GRCm39) |
C822* |
probably null |
Het |
| Noa1 |
A |
C |
5: 77,457,071 (GRCm39) |
L278R |
probably damaging |
Het |
| Nop16 |
A |
G |
13: 54,737,889 (GRCm39) |
|
probably benign |
Het |
| Odr4 |
T |
C |
1: 150,268,659 (GRCm39) |
|
probably benign |
Het |
| Or11h7 |
A |
T |
14: 50,891,450 (GRCm39) |
Y252F |
probably benign |
Het |
| Or5b12 |
A |
G |
19: 12,897,229 (GRCm39) |
V148A |
probably benign |
Het |
| Osbpl10 |
C |
T |
9: 114,890,962 (GRCm39) |
H117Y |
probably benign |
Het |
| Oxct1 |
A |
T |
15: 4,077,058 (GRCm39) |
E130D |
probably benign |
Het |
| Padi2 |
A |
G |
4: 140,676,575 (GRCm39) |
E571G |
possibly damaging |
Het |
| Pcdhac2 |
G |
A |
18: 37,278,717 (GRCm39) |
V566M |
probably benign |
Het |
| Pdcd11 |
G |
A |
19: 47,086,659 (GRCm39) |
E222K |
possibly damaging |
Het |
| Pira12 |
C |
A |
7: 3,897,204 (GRCm39) |
C544F |
probably damaging |
Het |
| Plekha2 |
A |
G |
8: 25,578,356 (GRCm39) |
|
probably null |
Het |
| Pogz |
T |
C |
3: 94,777,418 (GRCm39) |
L366P |
probably benign |
Het |
| Ppp4r3b |
A |
G |
11: 29,138,086 (GRCm39) |
I145V |
probably benign |
Het |
| Prkcd |
A |
G |
14: 30,320,407 (GRCm39) |
|
probably null |
Het |
| Ptprk |
T |
A |
10: 28,468,853 (GRCm39) |
H1438Q |
probably damaging |
Het |
| Rbm4 |
A |
T |
19: 4,842,650 (GRCm39) |
V63E |
possibly damaging |
Het |
| Sbk2 |
T |
A |
7: 4,961,938 (GRCm39) |
H116L |
probably damaging |
Het |
| Sdk1 |
A |
G |
5: 141,923,434 (GRCm39) |
T352A |
probably benign |
Het |
| Septin9 |
T |
A |
11: 117,250,264 (GRCm39) |
C529* |
probably null |
Het |
| Setx |
T |
A |
2: 29,038,663 (GRCm39) |
V1716D |
probably benign |
Het |
| Slc19a3 |
C |
T |
1: 82,997,162 (GRCm39) |
V349I |
probably benign |
Het |
| Slc27a4 |
C |
A |
2: 29,695,722 (GRCm39) |
R86S |
probably benign |
Het |
| Slc4a8 |
A |
G |
15: 100,696,059 (GRCm39) |
H613R |
possibly damaging |
Het |
| Smoc2 |
A |
G |
17: 14,545,884 (GRCm39) |
R58G |
probably damaging |
Het |
| Sphkap |
T |
A |
1: 83,254,021 (GRCm39) |
N1243Y |
probably damaging |
Het |
| Srsf5 |
T |
C |
12: 80,996,720 (GRCm39) |
S261P |
unknown |
Het |
| Tab1 |
A |
T |
15: 80,042,999 (GRCm39) |
T398S |
possibly damaging |
Het |
| Tas2r131 |
T |
A |
6: 132,934,705 (GRCm39) |
T35S |
probably benign |
Het |
| Tasor2 |
T |
C |
13: 3,625,714 (GRCm39) |
K1412R |
possibly damaging |
Het |
| Tigd4 |
T |
A |
3: 84,502,310 (GRCm39) |
V409E |
possibly damaging |
Het |
| Tlr12 |
T |
C |
4: 128,510,501 (GRCm39) |
Q583R |
probably benign |
Het |
| Tmprss9 |
T |
A |
10: 80,733,145 (GRCm39) |
C894S |
unknown |
Het |
| Topaz1 |
T |
A |
9: 122,578,250 (GRCm39) |
S387T |
probably benign |
Het |
| Tsfm |
T |
C |
10: 126,847,558 (GRCm39) |
R178G |
probably benign |
Het |
| Ttll13 |
T |
C |
7: 79,902,875 (GRCm39) |
I181T |
probably damaging |
Het |
| Ttyh3 |
T |
A |
5: 140,610,896 (GRCm39) |
K97N |
|
Het |
| Ubr4 |
A |
G |
4: 139,142,394 (GRCm39) |
E38G |
|
Het |
| Ugt2b37 |
T |
C |
5: 87,402,118 (GRCm39) |
Y171C |
probably damaging |
Het |
| Unc5b |
C |
A |
10: 60,601,020 (GRCm39) |
M935I |
probably benign |
Het |
| Usp34 |
T |
C |
11: 23,362,314 (GRCm39) |
S1606P |
|
Het |
| Vmn1r195 |
T |
C |
13: 22,463,244 (GRCm39) |
L238P |
probably damaging |
Het |
| Vmn2r85 |
T |
A |
10: 130,261,081 (GRCm39) |
M419L |
probably benign |
Het |
| Washc2 |
G |
T |
6: 116,236,020 (GRCm39) |
A1164S |
probably benign |
Het |
| Wdfy3 |
A |
T |
5: 102,042,940 (GRCm39) |
M1937K |
probably benign |
Het |
| Wdfy3 |
A |
T |
5: 102,099,265 (GRCm39) |
L261* |
probably null |
Het |
| Wdr64 |
A |
T |
1: 175,559,092 (GRCm39) |
Y285F |
probably benign |
Het |
| Wtap |
A |
G |
17: 13,199,797 (GRCm39) |
L62P |
probably damaging |
Het |
| Zfp1007 |
A |
C |
5: 109,825,170 (GRCm39) |
Y93* |
probably null |
Het |
| Zfp94 |
C |
A |
7: 24,002,498 (GRCm39) |
V315F |
probably benign |
Het |
| Zhx1 |
A |
T |
15: 57,911,798 (GRCm39) |
|
probably null |
Het |
|
| Other mutations in Flg2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00090:Flg2
|
APN |
3 |
93,109,416 (GRCm39) |
nonsense |
probably null |
|
|
IGL00092:Flg2
|
APN |
3 |
93,127,162 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL00985:Flg2
|
APN |
3 |
93,110,585 (GRCm39) |
missense |
unknown |
|
|
IGL01077:Flg2
|
APN |
3 |
93,127,513 (GRCm39) |
missense |
unknown |
|
|
IGL01093:Flg2
|
APN |
3 |
93,109,678 (GRCm39) |
missense |
unknown |
|
|
IGL01120:Flg2
|
APN |
3 |
93,108,475 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01473:Flg2
|
APN |
3 |
93,110,327 (GRCm39) |
missense |
unknown |
|
|
IGL01584:Flg2
|
APN |
3 |
93,122,777 (GRCm39) |
missense |
unknown |
|
|
IGL01584:Flg2
|
APN |
3 |
93,120,773 (GRCm39) |
missense |
unknown |
|
|
IGL01686:Flg2
|
APN |
3 |
93,109,591 (GRCm39) |
missense |
unknown |
|
|
IGL02207:Flg2
|
APN |
3 |
93,127,435 (GRCm39) |
missense |
unknown |
|
|
IGL02294:Flg2
|
APN |
3 |
93,111,053 (GRCm39) |
missense |
unknown |
|
|
IGL02418:Flg2
|
APN |
3 |
93,108,361 (GRCm39) |
missense |
probably benign |
0.26 |
|
IGL02581:Flg2
|
APN |
3 |
93,127,199 (GRCm39) |
missense |
unknown |
|
|
IGL02719:Flg2
|
APN |
3 |
93,127,438 (GRCm39) |
nonsense |
probably null |
|
|
IGL02795:Flg2
|
APN |
3 |
93,110,920 (GRCm39) |
missense |
unknown |
|
|
IGL02893:Flg2
|
APN |
3 |
93,110,920 (GRCm39) |
missense |
unknown |
|
|
IGL02958:Flg2
|
APN |
3 |
93,110,920 (GRCm39) |
missense |
unknown |
|
|
IGL03060:Flg2
|
APN |
3 |
93,110,920 (GRCm39) |
missense |
unknown |
|
|
IGL03088:Flg2
|
APN |
3 |
93,110,498 (GRCm39) |
missense |
unknown |
|
|
IGL03165:Flg2
|
APN |
3 |
93,121,918 (GRCm39) |
missense |
unknown |
|
|
IGL03342:Flg2
|
APN |
3 |
93,108,542 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03352:Flg2
|
APN |
3 |
93,109,801 (GRCm39) |
missense |
unknown |
|
|
IGL02796:Flg2
|
UTSW |
3 |
93,110,920 (GRCm39) |
missense |
unknown |
|
|
IGL02837:Flg2
|
UTSW |
3 |
93,109,044 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4618001:Flg2
|
UTSW |
3 |
93,111,088 (GRCm39) |
missense |
unknown |
|
|
R0087:Flg2
|
UTSW |
3 |
93,109,738 (GRCm39) |
missense |
unknown |
|
|
R0233:Flg2
|
UTSW |
3 |
93,109,104 (GRCm39) |
nonsense |
probably null |
|
|
R0233:Flg2
|
UTSW |
3 |
93,109,104 (GRCm39) |
nonsense |
probably null |
|
|
R0315:Flg2
|
UTSW |
3 |
93,122,029 (GRCm39) |
missense |
unknown |
|
|
R0390:Flg2
|
UTSW |
3 |
93,107,662 (GRCm39) |
splice site |
probably benign |
|
|
R0462:Flg2
|
UTSW |
3 |
93,108,744 (GRCm39) |
missense |
probably benign |
0.18 |
|
R0553:Flg2
|
UTSW |
3 |
93,110,891 (GRCm39) |
missense |
unknown |
|
|
R0828:Flg2
|
UTSW |
3 |
93,110,639 (GRCm39) |
missense |
unknown |
|
|
R1006:Flg2
|
UTSW |
3 |
93,108,514 (GRCm39) |
missense |
probably benign |
0.41 |
|
R1444:Flg2
|
UTSW |
3 |
93,109,620 (GRCm39) |
missense |
unknown |
|
|
R1497:Flg2
|
UTSW |
3 |
93,127,076 (GRCm39) |
missense |
unknown |
|
|
R1518:Flg2
|
UTSW |
3 |
93,110,445 (GRCm39) |
missense |
unknown |
|
|
R1737:Flg2
|
UTSW |
3 |
93,110,928 (GRCm39) |
missense |
unknown |
|
|
R1780:Flg2
|
UTSW |
3 |
93,110,306 (GRCm39) |
missense |
unknown |
|
|
R1797:Flg2
|
UTSW |
3 |
93,108,283 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2065:Flg2
|
UTSW |
3 |
93,109,538 (GRCm39) |
missense |
unknown |
|
|
R2168:Flg2
|
UTSW |
3 |
93,109,244 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2220:Flg2
|
UTSW |
3 |
93,109,492 (GRCm39) |
missense |
unknown |
|
|
R2292:Flg2
|
UTSW |
3 |
93,127,984 (GRCm39) |
missense |
unknown |
|
|
R2327:Flg2
|
UTSW |
3 |
93,110,913 (GRCm39) |
nonsense |
probably null |
|
|
R2512:Flg2
|
UTSW |
3 |
93,109,082 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3177:Flg2
|
UTSW |
3 |
93,122,195 (GRCm39) |
missense |
unknown |
|
|
R3277:Flg2
|
UTSW |
3 |
93,122,195 (GRCm39) |
missense |
unknown |
|
|
R3522:Flg2
|
UTSW |
3 |
93,127,334 (GRCm39) |
missense |
unknown |
|
|
R3779:Flg2
|
UTSW |
3 |
93,109,730 (GRCm39) |
missense |
unknown |
|
|
R3926:Flg2
|
UTSW |
3 |
93,110,522 (GRCm39) |
missense |
unknown |
|
|
R4082:Flg2
|
UTSW |
3 |
93,110,828 (GRCm39) |
missense |
unknown |
|
|
R4407:Flg2
|
UTSW |
3 |
93,122,176 (GRCm39) |
missense |
unknown |
|
|
R5152:Flg2
|
UTSW |
3 |
93,122,284 (GRCm39) |
missense |
unknown |
|
|
R5253:Flg2
|
UTSW |
3 |
93,108,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5290:Flg2
|
UTSW |
3 |
93,127,873 (GRCm39) |
missense |
unknown |
|
|
R5464:Flg2
|
UTSW |
3 |
93,109,277 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R5539:Flg2
|
UTSW |
3 |
93,127,753 (GRCm39) |
missense |
unknown |
|
|
R5622:Flg2
|
UTSW |
3 |
93,109,871 (GRCm39) |
missense |
unknown |
|
|
R5788:Flg2
|
UTSW |
3 |
93,108,296 (GRCm39) |
missense |
probably benign |
0.41 |
|
R5792:Flg2
|
UTSW |
3 |
93,110,804 (GRCm39) |
missense |
unknown |
|
|
R5831:Flg2
|
UTSW |
3 |
93,107,541 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5877:Flg2
|
UTSW |
3 |
93,110,756 (GRCm39) |
missense |
unknown |
|
|
R6041:Flg2
|
UTSW |
3 |
93,127,668 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6189:Flg2
|
UTSW |
3 |
93,127,381 (GRCm39) |
missense |
unknown |
|
|
R6214:Flg2
|
UTSW |
3 |
93,109,166 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R6215:Flg2
|
UTSW |
3 |
93,109,166 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R6239:Flg2
|
UTSW |
3 |
93,108,579 (GRCm39) |
missense |
probably benign |
0.36 |
|
R6288:Flg2
|
UTSW |
3 |
93,111,092 (GRCm39) |
missense |
unknown |
|
|
R6413:Flg2
|
UTSW |
3 |
93,127,683 (GRCm39) |
missense |
unknown |
|
|
R6457:Flg2
|
UTSW |
3 |
93,127,789 (GRCm39) |
missense |
unknown |
|
|
R6468:Flg2
|
UTSW |
3 |
93,121,728 (GRCm39) |
missense |
unknown |
|
|
R6667:Flg2
|
UTSW |
3 |
93,109,068 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R6930:Flg2
|
UTSW |
3 |
93,108,642 (GRCm39) |
nonsense |
probably null |
|
|
R6996:Flg2
|
UTSW |
3 |
93,110,256 (GRCm39) |
missense |
unknown |
|
|
R6996:Flg2
|
UTSW |
3 |
93,109,977 (GRCm39) |
missense |
unknown |
|
|
R7100:Flg2
|
UTSW |
3 |
93,111,018 (GRCm39) |
missense |
unknown |
|
|
R7133:Flg2
|
UTSW |
3 |
93,127,069 (GRCm39) |
missense |
unknown |
|
|
R7180:Flg2
|
UTSW |
3 |
93,110,140 (GRCm39) |
missense |
unknown |
|
|
R7325:Flg2
|
UTSW |
3 |
93,110,679 (GRCm39) |
missense |
unknown |
|
|
R7349:Flg2
|
UTSW |
3 |
93,127,513 (GRCm39) |
missense |
unknown |
|
|
R7531:Flg2
|
UTSW |
3 |
93,108,177 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7571:Flg2
|
UTSW |
3 |
93,127,303 (GRCm39) |
nonsense |
probably null |
|
|
R7684:Flg2
|
UTSW |
3 |
93,126,956 (GRCm39) |
missense |
unknown |
|
|
R7853:Flg2
|
UTSW |
3 |
93,128,054 (GRCm39) |
missense |
unknown |
|
|
R8031:Flg2
|
UTSW |
3 |
93,127,521 (GRCm39) |
missense |
unknown |
|
|
R8078:Flg2
|
UTSW |
3 |
93,107,582 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8142:Flg2
|
UTSW |
3 |
93,122,782 (GRCm39) |
nonsense |
probably null |
|
|
R8156:Flg2
|
UTSW |
3 |
93,127,390 (GRCm39) |
missense |
unknown |
|
|
R8172:Flg2
|
UTSW |
3 |
93,108,468 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8204:Flg2
|
UTSW |
3 |
93,110,074 (GRCm39) |
missense |
unknown |
|
|
R8262:Flg2
|
UTSW |
3 |
93,127,517 (GRCm39) |
missense |
unknown |
|
|
R8269:Flg2
|
UTSW |
3 |
93,109,187 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R8290:Flg2
|
UTSW |
3 |
93,110,069 (GRCm39) |
missense |
unknown |
|
|
R8444:Flg2
|
UTSW |
3 |
93,107,585 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8670:Flg2
|
UTSW |
3 |
93,108,791 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8755:Flg2
|
UTSW |
3 |
93,108,120 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9039:Flg2
|
UTSW |
3 |
93,110,899 (GRCm39) |
missense |
unknown |
|
|
R9116:Flg2
|
UTSW |
3 |
93,109,591 (GRCm39) |
missense |
unknown |
|
|
R9214:Flg2
|
UTSW |
3 |
93,110,884 (GRCm39) |
missense |
unknown |
|
|
R9231:Flg2
|
UTSW |
3 |
93,109,508 (GRCm39) |
missense |
unknown |
|
|
R9553:Flg2
|
UTSW |
3 |
93,121,901 (GRCm39) |
missense |
unknown |
|
|
R9607:Flg2
|
UTSW |
3 |
93,108,719 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9735:Flg2
|
UTSW |
3 |
93,127,669 (GRCm39) |
missense |
unknown |
|
|
R9752:Flg2
|
UTSW |
3 |
93,108,467 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Z1177:Flg2
|
UTSW |
3 |
93,110,045 (GRCm39) |
missense |
unknown |
|
|
Z1177:Flg2
|
UTSW |
3 |
93,109,727 (GRCm39) |
missense |
unknown |
|
|
| Predicted Primers |
PCR Primer
(F):5'- ACCCATACTTGTATGTTGAGGTAG -3'
(R):5'- AGTGCATGTTCCAACTAATCTGAG -3'
Sequencing Primer
(F):5'- GTGGTCCAACAATGCTGTCACAG -3'
(R):5'- CAGCAGTTCCTTTAGCTCA -3'
|
| Posted On |
2019-11-26 |
Incidental Mutation