Incidental Mutation 'R7818:Mical2'
| ID |
601662 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Mical2
|
| Ensembl Gene |
ENSMUSG00000038244 |
| Gene Name |
microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| Synonyms |
4921517J23Rik, Ebitein1, 5330438E18Rik, Micalcl |
| MMRRC Submission |
045872-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.242)
|
| Stock # |
R7818 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
7 |
| Chromosomal Location |
111825063-112012313 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 111944514 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Tyrosine to Cysteine
at position 948
(Y948C)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000047639
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000037991]
[ENSMUST00000050149]
|
| AlphaFold |
Q8BML1
Q9D5U9 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000037991
AA Change: Y948C
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000047639
Gene: ENSMUSG00000038244
AA Change: Y948C
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:FAD_binding_3
|
86 |
143 |
1e-8 |
PFAM |
|
Pfam:FAD_binding_2
|
88 |
127 |
3.2e-6 |
PFAM |
|
low complexity region
|
175 |
188 |
N/A |
INTRINSIC |
|
low complexity region
|
500 |
515 |
N/A |
INTRINSIC |
|
CH
|
518 |
617 |
4.14e-17 |
SMART |
|
low complexity region
|
691 |
700 |
N/A |
INTRINSIC |
|
low complexity region
|
894 |
925 |
N/A |
INTRINSIC |
|
LIM
|
979 |
1033 |
9.91e-10 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000050149
|
| SMART Domains |
Protein: ENSMUSP00000051163
Gene: ENSMUSG00000038244
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:FAD_binding_3
|
86 |
143 |
1.1e-8 |
PFAM |
|
Pfam:FAD_binding_2
|
88 |
127 |
1.5e-6 |
PFAM |
|
Pfam:Pyr_redox_2
|
88 |
259 |
1.3e-6 |
PFAM |
|
low complexity region
|
500 |
515 |
N/A |
INTRINSIC |
|
CH
|
518 |
617 |
4.14e-17 |
SMART |
|
low complexity region
|
691 |
700 |
N/A |
INTRINSIC |
|
LIM
|
752 |
806 |
9.91e-10 |
SMART |
|
low complexity region
|
918 |
926 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000144509
|
| SMART Domains |
Protein: ENSMUSP00000123341
Gene: ENSMUSG00000038244
| Domain | Start | End | E-Value | Type |
|---|
|
LIM
|
14 |
68 |
9.91e-10 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000215412
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000216652
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.5%
- 20x: 98.5%
|
| Validation Efficiency |
99% (88/89) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a monooxygenase that enhances depolymerization of F-actin and is therefore involved in cytoskeletal dynamics. The encoded protein is a regulator of the SRF signaling pathway. Increased expression of this gene has been associated with cancer progression and metastasis. [provided by RefSeq, Oct 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 88 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4931429L15Rik |
T |
A |
9: 46,215,519 (GRCm39) |
R342S |
probably benign |
Het |
| Aatk |
C |
T |
11: 119,912,281 (GRCm39) |
V55I |
probably benign |
Het |
| Abhd10 |
T |
A |
16: 45,557,916 (GRCm39) |
I128L |
probably benign |
Het |
| Abraxas1 |
T |
A |
5: 100,954,176 (GRCm39) |
M325L |
probably benign |
Het |
| Adgrb2 |
C |
A |
4: 129,908,353 (GRCm39) |
L1087I |
probably damaging |
Het |
| Adgrb2 |
C |
T |
4: 129,908,762 (GRCm39) |
P1124S |
possibly damaging |
Het |
| Akap9 |
T |
A |
5: 4,063,875 (GRCm39) |
Y1741* |
probably null |
Het |
| Ap1g2 |
A |
T |
14: 55,337,181 (GRCm39) |
V718D |
probably benign |
Het |
| Asph |
A |
T |
4: 9,475,015 (GRCm39) |
M637K |
probably damaging |
Het |
| Atp2c1 |
T |
C |
9: 105,291,956 (GRCm39) |
I869V |
probably benign |
Het |
| C1ra |
G |
A |
6: 124,494,684 (GRCm39) |
E316K |
probably benign |
Het |
| Cacna1e |
T |
C |
1: 154,274,152 (GRCm39) |
D2251G |
probably damaging |
Het |
| Camk2b |
A |
G |
11: 5,927,812 (GRCm39) |
S413P |
probably benign |
Het |
| Casz1 |
G |
A |
4: 149,030,533 (GRCm39) |
C1184Y |
probably damaging |
Het |
| Cbr4 |
G |
A |
8: 61,940,976 (GRCm39) |
V32I |
probably benign |
Het |
| Ccdc166 |
A |
G |
15: 75,852,864 (GRCm39) |
S368P |
possibly damaging |
Het |
| Ccdc170 |
A |
G |
10: 4,499,603 (GRCm39) |
N508S |
probably benign |
Het |
| Ccdc187 |
A |
G |
2: 26,166,186 (GRCm39) |
S748P |
possibly damaging |
Het |
| Cdca8 |
A |
T |
4: 124,820,456 (GRCm39) |
|
probably null |
Het |
| Cep120 |
T |
C |
18: 53,856,175 (GRCm39) |
D414G |
probably benign |
Het |
| Dcp1a |
G |
T |
14: 30,201,678 (GRCm39) |
A34S |
probably damaging |
Het |
| Ddit3 |
C |
T |
10: 127,131,662 (GRCm39) |
T70I |
probably benign |
Het |
| Dlg2 |
C |
G |
7: 91,589,225 (GRCm39) |
A313G |
probably damaging |
Het |
| Dnah9 |
A |
T |
11: 65,916,037 (GRCm39) |
V2305D |
possibly damaging |
Het |
| Dock1 |
T |
A |
7: 134,365,594 (GRCm39) |
D427E |
probably damaging |
Het |
| Dolpp1 |
T |
C |
2: 30,286,503 (GRCm39) |
L141P |
probably benign |
Het |
| Dsc2 |
A |
T |
18: 20,183,189 (GRCm39) |
D76E |
probably damaging |
Het |
| Dusp7 |
C |
A |
9: 106,246,329 (GRCm39) |
N111K |
probably benign |
Het |
| Fam193a |
A |
G |
5: 34,622,997 (GRCm39) |
E1195G |
possibly damaging |
Het |
| Fig4 |
A |
G |
10: 41,139,162 (GRCm39) |
L347P |
probably damaging |
Het |
| Frem1 |
T |
C |
4: 82,932,245 (GRCm39) |
E152G |
probably damaging |
Het |
| Galnt2 |
G |
T |
8: 125,056,527 (GRCm39) |
D234Y |
probably damaging |
Het |
| H1f3 |
C |
T |
13: 23,739,165 (GRCm39) |
|
probably benign |
Het |
| Igkv4-59 |
T |
C |
6: 69,415,475 (GRCm39) |
T27A |
possibly damaging |
Het |
| Ihh |
T |
C |
1: 74,985,804 (GRCm39) |
D227G |
possibly damaging |
Het |
| Il1rap |
T |
A |
16: 26,517,597 (GRCm39) |
C266S |
probably damaging |
Het |
| Iqcf4 |
A |
T |
9: 106,447,738 (GRCm39) |
L57* |
probably null |
Het |
| Kif2b |
A |
G |
11: 91,466,952 (GRCm39) |
S444P |
probably damaging |
Het |
| Lmf1 |
T |
G |
17: 25,881,565 (GRCm39) |
I538S |
probably benign |
Het |
| Mr1 |
G |
A |
1: 155,006,382 (GRCm39) |
Q322* |
probably null |
Het |
| Mroh2a |
T |
C |
1: 88,162,334 (GRCm39) |
|
probably null |
Het |
| Mup6 |
A |
G |
4: 60,004,884 (GRCm39) |
T100A |
probably benign |
Het |
| Mybpc1 |
T |
A |
10: 88,394,529 (GRCm39) |
D266V |
probably damaging |
Het |
| Myocos |
T |
C |
1: 162,475,063 (GRCm39) |
N48S |
unknown |
Het |
| Naf1 |
G |
A |
8: 67,342,028 (GRCm39) |
G551E |
probably damaging |
Het |
| Nrarp |
A |
G |
2: 25,071,250 (GRCm39) |
N43S |
possibly damaging |
Het |
| Or4a80 |
A |
G |
2: 89,582,288 (GRCm39) |
S295P |
possibly damaging |
Het |
| Or5p52 |
G |
A |
7: 107,502,230 (GRCm39) |
C102Y |
probably benign |
Het |
| Or7a40 |
A |
C |
16: 16,491,437 (GRCm39) |
M136R |
probably damaging |
Het |
| Or7g19 |
T |
A |
9: 18,856,305 (GRCm39) |
Y120* |
probably null |
Het |
| Or8b57 |
T |
A |
9: 40,004,008 (GRCm39) |
M85L |
probably damaging |
Het |
| Padi3 |
T |
A |
4: 140,525,453 (GRCm39) |
T177S |
possibly damaging |
Het |
| Pde3b |
A |
G |
7: 114,090,675 (GRCm39) |
M305V |
probably damaging |
Het |
| Pde6a |
T |
A |
18: 61,414,580 (GRCm39) |
|
probably null |
Het |
| Plscr4 |
C |
T |
9: 92,372,843 (GRCm39) |
R322* |
probably null |
Het |
| Prph |
A |
G |
15: 98,955,753 (GRCm39) |
T446A |
probably damaging |
Het |
| Pwwp2b |
T |
C |
7: 138,835,240 (GRCm39) |
V227A |
probably benign |
Het |
| Rev3l |
T |
C |
10: 39,699,898 (GRCm39) |
I1465T |
possibly damaging |
Het |
| Rin1 |
A |
G |
19: 5,102,219 (GRCm39) |
S243G |
probably benign |
Het |
| Ripor3 |
A |
T |
2: 167,831,346 (GRCm39) |
I485N |
probably benign |
Het |
| Rnpc3 |
G |
T |
3: 113,423,600 (GRCm39) |
P35Q |
probably damaging |
Het |
| Sbpl |
G |
T |
17: 24,172,236 (GRCm39) |
Q228K |
unknown |
Het |
| Scn11a |
A |
C |
9: 119,613,177 (GRCm39) |
N804K |
probably damaging |
Het |
| Selenoo |
A |
G |
15: 88,981,019 (GRCm39) |
T453A |
probably damaging |
Het |
| Sez6 |
C |
T |
11: 77,867,728 (GRCm39) |
P882S |
probably damaging |
Het |
| Skint5 |
C |
T |
4: 113,799,923 (GRCm39) |
R82H |
possibly damaging |
Het |
| Slc18a2 |
A |
C |
19: 59,251,593 (GRCm39) |
T115P |
probably benign |
Het |
| Slc1a2 |
A |
G |
2: 102,574,301 (GRCm39) |
D237G |
probably benign |
Het |
| Spidr |
T |
C |
16: 15,932,729 (GRCm39) |
S184G |
probably damaging |
Het |
| Stag3 |
A |
T |
5: 138,299,705 (GRCm39) |
Q872L |
probably benign |
Het |
| Suds3 |
T |
C |
5: 117,253,814 (GRCm39) |
|
probably benign |
Het |
| Sv2c |
T |
A |
13: 96,123,328 (GRCm39) |
K382* |
probably null |
Het |
| Taf2 |
T |
C |
15: 54,929,326 (GRCm39) |
I77V |
probably benign |
Het |
| Tcof1 |
G |
C |
18: 60,962,123 (GRCm39) |
A702G |
possibly damaging |
Het |
| Tdrd3 |
G |
T |
14: 87,709,636 (GRCm39) |
C100F |
probably damaging |
Het |
| Tek |
T |
A |
4: 94,715,953 (GRCm39) |
H458Q |
possibly damaging |
Het |
| Tes |
C |
A |
6: 17,099,743 (GRCm39) |
P246Q |
probably damaging |
Het |
| Tgif1 |
A |
T |
17: 71,156,603 (GRCm39) |
|
probably null |
Het |
| Tlr11 |
A |
T |
14: 50,599,285 (GRCm39) |
N424Y |
probably damaging |
Het |
| Tmc8 |
A |
T |
11: 117,682,953 (GRCm39) |
N626I |
probably damaging |
Het |
| Tmem132c |
T |
A |
5: 127,641,152 (GRCm39) |
*1108K |
probably null |
Het |
| Tnks |
A |
T |
8: 35,340,182 (GRCm39) |
Y479N |
probably benign |
Het |
| Trip12 |
C |
T |
1: 84,738,527 (GRCm39) |
G776D |
probably damaging |
Het |
| Tssk1 |
A |
G |
16: 17,712,311 (GRCm39) |
E32G |
probably benign |
Het |
| Ube2o |
T |
C |
11: 116,434,736 (GRCm39) |
D575G |
probably damaging |
Het |
| Uckl1 |
A |
T |
2: 181,216,460 (GRCm39) |
M16K |
probably damaging |
Het |
| Zfp948 |
A |
T |
17: 21,807,985 (GRCm39) |
E392D |
probably benign |
Het |
| Zmynd8 |
G |
A |
2: 165,684,751 (GRCm39) |
T167I |
probably damaging |
Het |
|
| Other mutations in Mical2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00504:Mical2
|
APN |
7 |
111,981,352 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL00886:Mical2
|
APN |
7 |
111,914,279 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00934:Mical2
|
APN |
7 |
111,948,610 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00941:Mical2
|
APN |
7 |
111,920,652 (GRCm39) |
splice site |
probably benign |
|
|
IGL01020:Mical2
|
APN |
7 |
111,914,283 (GRCm39) |
splice site |
probably benign |
|
|
IGL01395:Mical2
|
APN |
7 |
111,922,792 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01658:Mical2
|
APN |
7 |
111,914,205 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01775:Mical2
|
APN |
7 |
111,981,269 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL02040:Mical2
|
APN |
7 |
111,910,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02051:Mical2
|
APN |
7 |
111,980,597 (GRCm39) |
missense |
probably benign |
0.30 |
|
IGL02388:Mical2
|
APN |
7 |
111,934,620 (GRCm39) |
missense |
probably benign |
|
|
IGL02551:Mical2
|
APN |
7 |
111,923,197 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02578:Mical2
|
APN |
7 |
111,950,580 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02751:Mical2
|
APN |
7 |
111,931,243 (GRCm39) |
missense |
probably benign |
0.11 |
|
IGL03114:Mical2
|
APN |
7 |
111,996,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0091:Mical2
|
UTSW |
7 |
111,980,503 (GRCm39) |
missense |
probably benign |
0.05 |
|
R0101:Mical2
|
UTSW |
7 |
111,936,074 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R0415:Mical2
|
UTSW |
7 |
111,980,235 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0504:Mical2
|
UTSW |
7 |
111,870,524 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0594:Mical2
|
UTSW |
7 |
111,917,657 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0609:Mical2
|
UTSW |
7 |
111,920,647 (GRCm39) |
splice site |
probably null |
|
|
R0962:Mical2
|
UTSW |
7 |
111,979,624 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1521:Mical2
|
UTSW |
7 |
111,980,817 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1542:Mical2
|
UTSW |
7 |
111,908,675 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1611:Mical2
|
UTSW |
7 |
111,980,671 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1740:Mical2
|
UTSW |
7 |
111,933,043 (GRCm39) |
missense |
probably benign |
|
|
R1815:Mical2
|
UTSW |
7 |
112,012,109 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1855:Mical2
|
UTSW |
7 |
111,944,489 (GRCm39) |
missense |
probably benign |
0.21 |
|
R1958:Mical2
|
UTSW |
7 |
111,980,311 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1962:Mical2
|
UTSW |
7 |
112,012,051 (GRCm39) |
missense |
probably benign |
0.14 |
|
R2086:Mical2
|
UTSW |
7 |
111,917,810 (GRCm39) |
missense |
probably benign |
0.31 |
|
R2136:Mical2
|
UTSW |
7 |
111,870,722 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R2418:Mical2
|
UTSW |
7 |
111,919,941 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2439:Mical2
|
UTSW |
7 |
111,994,002 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3053:Mical2
|
UTSW |
7 |
111,910,630 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3979:Mical2
|
UTSW |
7 |
112,006,885 (GRCm39) |
splice site |
probably null |
|
|
R4308:Mical2
|
UTSW |
7 |
111,931,199 (GRCm39) |
missense |
probably benign |
0.27 |
|
R4551:Mical2
|
UTSW |
7 |
111,981,123 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R4583:Mical2
|
UTSW |
7 |
112,012,154 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4663:Mical2
|
UTSW |
7 |
111,927,884 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R4868:Mical2
|
UTSW |
7 |
111,917,831 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4902:Mical2
|
UTSW |
7 |
111,936,107 (GRCm39) |
missense |
probably benign |
|
|
R5112:Mical2
|
UTSW |
7 |
111,919,818 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5459:Mical2
|
UTSW |
7 |
111,981,444 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5487:Mical2
|
UTSW |
7 |
111,919,842 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5563:Mical2
|
UTSW |
7 |
111,914,185 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5763:Mical2
|
UTSW |
7 |
111,973,861 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5817:Mical2
|
UTSW |
7 |
111,922,866 (GRCm39) |
missense |
probably benign |
|
|
R5987:Mical2
|
UTSW |
7 |
111,934,155 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6042:Mical2
|
UTSW |
7 |
111,979,619 (GRCm39) |
missense |
probably benign |
0.40 |
|
R6087:Mical2
|
UTSW |
7 |
111,917,692 (GRCm39) |
nonsense |
probably null |
|
|
R6189:Mical2
|
UTSW |
7 |
112,012,087 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6209:Mical2
|
UTSW |
7 |
111,923,293 (GRCm39) |
splice site |
probably null |
|
|
R6311:Mical2
|
UTSW |
7 |
111,922,765 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6319:Mical2
|
UTSW |
7 |
111,927,884 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R6578:Mical2
|
UTSW |
7 |
111,910,652 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6750:Mical2
|
UTSW |
7 |
111,981,046 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6782:Mical2
|
UTSW |
7 |
111,945,968 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6798:Mical2
|
UTSW |
7 |
111,975,266 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R7061:Mical2
|
UTSW |
7 |
111,946,008 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7147:Mical2
|
UTSW |
7 |
111,922,810 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R7260:Mical2
|
UTSW |
7 |
111,919,001 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7266:Mical2
|
UTSW |
7 |
111,902,963 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7347:Mical2
|
UTSW |
7 |
111,981,358 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7391:Mical2
|
UTSW |
7 |
111,919,816 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7724:Mical2
|
UTSW |
7 |
111,922,833 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7747:Mical2
|
UTSW |
7 |
111,933,046 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7783:Mical2
|
UTSW |
7 |
112,012,183 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7824:Mical2
|
UTSW |
7 |
112,006,844 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7995:Mical2
|
UTSW |
7 |
111,980,975 (GRCm39) |
missense |
probably benign |
0.31 |
|
R8022:Mical2
|
UTSW |
7 |
111,902,974 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8429:Mical2
|
UTSW |
7 |
111,944,460 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8505:Mical2
|
UTSW |
7 |
111,919,007 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8532:Mical2
|
UTSW |
7 |
111,917,751 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8830:Mical2
|
UTSW |
7 |
111,980,403 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8862:Mical2
|
UTSW |
7 |
111,910,574 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8906:Mical2
|
UTSW |
7 |
111,980,671 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8988:Mical2
|
UTSW |
7 |
111,910,661 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R9006:Mical2
|
UTSW |
7 |
111,981,323 (GRCm39) |
missense |
probably benign |
0.13 |
|
R9123:Mical2
|
UTSW |
7 |
111,870,589 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9127:Mical2
|
UTSW |
7 |
111,870,589 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9128:Mical2
|
UTSW |
7 |
111,870,589 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9129:Mical2
|
UTSW |
7 |
111,870,589 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9140:Mical2
|
UTSW |
7 |
112,006,826 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9187:Mical2
|
UTSW |
7 |
111,902,797 (GRCm39) |
nonsense |
probably null |
|
|
R9233:Mical2
|
UTSW |
7 |
111,981,399 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9304:Mical2
|
UTSW |
7 |
111,980,974 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9310:Mical2
|
UTSW |
7 |
111,950,920 (GRCm39) |
missense |
probably benign |
0.45 |
|
R9377:Mical2
|
UTSW |
7 |
111,981,246 (GRCm39) |
missense |
probably benign |
0.10 |
|
R9399:Mical2
|
UTSW |
7 |
111,946,082 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9457:Mical2
|
UTSW |
7 |
112,010,665 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9500:Mical2
|
UTSW |
7 |
111,936,054 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R9620:Mical2
|
UTSW |
7 |
111,980,403 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9652:Mical2
|
UTSW |
7 |
111,945,996 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9657:Mical2
|
UTSW |
7 |
111,921,806 (GRCm39) |
missense |
probably benign |
0.37 |
|
R9756:Mical2
|
UTSW |
7 |
111,902,928 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9789:Mical2
|
UTSW |
7 |
111,945,996 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF008:Mical2
|
UTSW |
7 |
111,922,833 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0062:Mical2
|
UTSW |
7 |
111,946,050 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATAACTCTGGCATCTACTCCTGG -3'
(R):5'- GGATCCAGCCGACTTTCAAC -3'
Sequencing Primer
(F):5'- GAGACTCTGGGGTTCCACTTTC -3'
(R):5'- GCCGACTTTCAACACCCCTG -3'
|
| Posted On |
2019-12-03 |
Incidental Mutation