Incidental Mutation 'R7818:Mybpc1'
| ID |
601681 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Mybpc1
|
| Ensembl Gene |
ENSMUSG00000020061 |
| Gene Name |
myosin binding protein C, slow-type |
| Synonyms |
Slow-type C-protein, 8030451F13Rik |
| MMRRC Submission |
045872-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.862)
|
| Stock # |
R7818 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
10 |
| Chromosomal Location |
88354141-88441014 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 88394529 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Valine
at position 266
(D266V)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000112615
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000119185]
[ENSMUST00000121629]
|
| AlphaFold |
A0A571BEN1 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000119185
AA Change: D252V
PolyPhen 2
Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000112699
Gene: ENSMUSG00000020061
AA Change: D252V
| Domain | Start | End | E-Value | Type |
|---|
|
IG
|
51 |
147 |
1.96e-6 |
SMART |
|
low complexity region
|
221 |
233 |
N/A |
INTRINSIC |
|
IG
|
246 |
325 |
4.53e-2 |
SMART |
|
IG
|
335 |
416 |
1.13e-2 |
SMART |
|
IG
|
426 |
506 |
6.97e-3 |
SMART |
|
IG
|
519 |
604 |
2.83e-3 |
SMART |
|
FN3
|
607 |
690 |
4.28e-10 |
SMART |
|
FN3
|
705 |
788 |
1.49e-9 |
SMART |
|
low complexity region
|
800 |
812 |
N/A |
INTRINSIC |
|
IG
|
815 |
898 |
9.06e-2 |
SMART |
|
FN3
|
901 |
983 |
2.06e-12 |
SMART |
|
IGc2
|
1028 |
1095 |
1.88e-8 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000121629
AA Change: D266V
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000112615
Gene: ENSMUSG00000020061
AA Change: D266V
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
8 |
27 |
N/A |
INTRINSIC |
|
IG
|
65 |
161 |
1.96e-6 |
SMART |
|
low complexity region
|
235 |
247 |
N/A |
INTRINSIC |
|
IG
|
260 |
339 |
4.53e-2 |
SMART |
|
IG
|
349 |
430 |
1.13e-2 |
SMART |
|
IG
|
440 |
520 |
6.97e-3 |
SMART |
|
IG
|
533 |
618 |
2.83e-3 |
SMART |
|
FN3
|
621 |
704 |
4.28e-10 |
SMART |
|
FN3
|
719 |
802 |
1.49e-9 |
SMART |
|
low complexity region
|
814 |
826 |
N/A |
INTRINSIC |
|
IG
|
829 |
912 |
9.06e-2 |
SMART |
|
FN3
|
915 |
997 |
2.06e-12 |
SMART |
|
IGc2
|
1042 |
1109 |
1.88e-8 |
SMART |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.5%
- 20x: 98.5%
|
| Validation Efficiency |
99% (88/89) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the myosin-binding protein C family. Myosin-binding protein C family members are myosin-associated proteins found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. The encoded protein is the slow skeletal muscle isoform of myosin-binding protein C and plays an important role in muscle contraction by recruiting muscle-type creatine kinase to myosin filaments. Mutations in this gene are associated with distal arthrogryposis type I. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 88 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4931429L15Rik |
T |
A |
9: 46,215,519 (GRCm39) |
R342S |
probably benign |
Het |
| Aatk |
C |
T |
11: 119,912,281 (GRCm39) |
V55I |
probably benign |
Het |
| Abhd10 |
T |
A |
16: 45,557,916 (GRCm39) |
I128L |
probably benign |
Het |
| Abraxas1 |
T |
A |
5: 100,954,176 (GRCm39) |
M325L |
probably benign |
Het |
| Adgrb2 |
C |
A |
4: 129,908,353 (GRCm39) |
L1087I |
probably damaging |
Het |
| Adgrb2 |
C |
T |
4: 129,908,762 (GRCm39) |
P1124S |
possibly damaging |
Het |
| Akap9 |
T |
A |
5: 4,063,875 (GRCm39) |
Y1741* |
probably null |
Het |
| Ap1g2 |
A |
T |
14: 55,337,181 (GRCm39) |
V718D |
probably benign |
Het |
| Asph |
A |
T |
4: 9,475,015 (GRCm39) |
M637K |
probably damaging |
Het |
| Atp2c1 |
T |
C |
9: 105,291,956 (GRCm39) |
I869V |
probably benign |
Het |
| C1ra |
G |
A |
6: 124,494,684 (GRCm39) |
E316K |
probably benign |
Het |
| Cacna1e |
T |
C |
1: 154,274,152 (GRCm39) |
D2251G |
probably damaging |
Het |
| Camk2b |
A |
G |
11: 5,927,812 (GRCm39) |
S413P |
probably benign |
Het |
| Casz1 |
G |
A |
4: 149,030,533 (GRCm39) |
C1184Y |
probably damaging |
Het |
| Cbr4 |
G |
A |
8: 61,940,976 (GRCm39) |
V32I |
probably benign |
Het |
| Ccdc166 |
A |
G |
15: 75,852,864 (GRCm39) |
S368P |
possibly damaging |
Het |
| Ccdc170 |
A |
G |
10: 4,499,603 (GRCm39) |
N508S |
probably benign |
Het |
| Ccdc187 |
A |
G |
2: 26,166,186 (GRCm39) |
S748P |
possibly damaging |
Het |
| Cdca8 |
A |
T |
4: 124,820,456 (GRCm39) |
|
probably null |
Het |
| Cep120 |
T |
C |
18: 53,856,175 (GRCm39) |
D414G |
probably benign |
Het |
| Dcp1a |
G |
T |
14: 30,201,678 (GRCm39) |
A34S |
probably damaging |
Het |
| Ddit3 |
C |
T |
10: 127,131,662 (GRCm39) |
T70I |
probably benign |
Het |
| Dlg2 |
C |
G |
7: 91,589,225 (GRCm39) |
A313G |
probably damaging |
Het |
| Dnah9 |
A |
T |
11: 65,916,037 (GRCm39) |
V2305D |
possibly damaging |
Het |
| Dock1 |
T |
A |
7: 134,365,594 (GRCm39) |
D427E |
probably damaging |
Het |
| Dolpp1 |
T |
C |
2: 30,286,503 (GRCm39) |
L141P |
probably benign |
Het |
| Dsc2 |
A |
T |
18: 20,183,189 (GRCm39) |
D76E |
probably damaging |
Het |
| Dusp7 |
C |
A |
9: 106,246,329 (GRCm39) |
N111K |
probably benign |
Het |
| Fam193a |
A |
G |
5: 34,622,997 (GRCm39) |
E1195G |
possibly damaging |
Het |
| Fig4 |
A |
G |
10: 41,139,162 (GRCm39) |
L347P |
probably damaging |
Het |
| Frem1 |
T |
C |
4: 82,932,245 (GRCm39) |
E152G |
probably damaging |
Het |
| Galnt2 |
G |
T |
8: 125,056,527 (GRCm39) |
D234Y |
probably damaging |
Het |
| H1f3 |
C |
T |
13: 23,739,165 (GRCm39) |
|
probably benign |
Het |
| Igkv4-59 |
T |
C |
6: 69,415,475 (GRCm39) |
T27A |
possibly damaging |
Het |
| Ihh |
T |
C |
1: 74,985,804 (GRCm39) |
D227G |
possibly damaging |
Het |
| Il1rap |
T |
A |
16: 26,517,597 (GRCm39) |
C266S |
probably damaging |
Het |
| Iqcf4 |
A |
T |
9: 106,447,738 (GRCm39) |
L57* |
probably null |
Het |
| Kif2b |
A |
G |
11: 91,466,952 (GRCm39) |
S444P |
probably damaging |
Het |
| Lmf1 |
T |
G |
17: 25,881,565 (GRCm39) |
I538S |
probably benign |
Het |
| Mical2 |
A |
G |
7: 111,944,514 (GRCm39) |
Y948C |
probably damaging |
Het |
| Mr1 |
G |
A |
1: 155,006,382 (GRCm39) |
Q322* |
probably null |
Het |
| Mroh2a |
T |
C |
1: 88,162,334 (GRCm39) |
|
probably null |
Het |
| Mup6 |
A |
G |
4: 60,004,884 (GRCm39) |
T100A |
probably benign |
Het |
| Myocos |
T |
C |
1: 162,475,063 (GRCm39) |
N48S |
unknown |
Het |
| Naf1 |
G |
A |
8: 67,342,028 (GRCm39) |
G551E |
probably damaging |
Het |
| Nrarp |
A |
G |
2: 25,071,250 (GRCm39) |
N43S |
possibly damaging |
Het |
| Or4a80 |
A |
G |
2: 89,582,288 (GRCm39) |
S295P |
possibly damaging |
Het |
| Or5p52 |
G |
A |
7: 107,502,230 (GRCm39) |
C102Y |
probably benign |
Het |
| Or7a40 |
A |
C |
16: 16,491,437 (GRCm39) |
M136R |
probably damaging |
Het |
| Or7g19 |
T |
A |
9: 18,856,305 (GRCm39) |
Y120* |
probably null |
Het |
| Or8b57 |
T |
A |
9: 40,004,008 (GRCm39) |
M85L |
probably damaging |
Het |
| Padi3 |
T |
A |
4: 140,525,453 (GRCm39) |
T177S |
possibly damaging |
Het |
| Pde3b |
A |
G |
7: 114,090,675 (GRCm39) |
M305V |
probably damaging |
Het |
| Pde6a |
T |
A |
18: 61,414,580 (GRCm39) |
|
probably null |
Het |
| Plscr4 |
C |
T |
9: 92,372,843 (GRCm39) |
R322* |
probably null |
Het |
| Prph |
A |
G |
15: 98,955,753 (GRCm39) |
T446A |
probably damaging |
Het |
| Pwwp2b |
T |
C |
7: 138,835,240 (GRCm39) |
V227A |
probably benign |
Het |
| Rev3l |
T |
C |
10: 39,699,898 (GRCm39) |
I1465T |
possibly damaging |
Het |
| Rin1 |
A |
G |
19: 5,102,219 (GRCm39) |
S243G |
probably benign |
Het |
| Ripor3 |
A |
T |
2: 167,831,346 (GRCm39) |
I485N |
probably benign |
Het |
| Rnpc3 |
G |
T |
3: 113,423,600 (GRCm39) |
P35Q |
probably damaging |
Het |
| Sbpl |
G |
T |
17: 24,172,236 (GRCm39) |
Q228K |
unknown |
Het |
| Scn11a |
A |
C |
9: 119,613,177 (GRCm39) |
N804K |
probably damaging |
Het |
| Selenoo |
A |
G |
15: 88,981,019 (GRCm39) |
T453A |
probably damaging |
Het |
| Sez6 |
C |
T |
11: 77,867,728 (GRCm39) |
P882S |
probably damaging |
Het |
| Skint5 |
C |
T |
4: 113,799,923 (GRCm39) |
R82H |
possibly damaging |
Het |
| Slc18a2 |
A |
C |
19: 59,251,593 (GRCm39) |
T115P |
probably benign |
Het |
| Slc1a2 |
A |
G |
2: 102,574,301 (GRCm39) |
D237G |
probably benign |
Het |
| Spidr |
T |
C |
16: 15,932,729 (GRCm39) |
S184G |
probably damaging |
Het |
| Stag3 |
A |
T |
5: 138,299,705 (GRCm39) |
Q872L |
probably benign |
Het |
| Suds3 |
T |
C |
5: 117,253,814 (GRCm39) |
|
probably benign |
Het |
| Sv2c |
T |
A |
13: 96,123,328 (GRCm39) |
K382* |
probably null |
Het |
| Taf2 |
T |
C |
15: 54,929,326 (GRCm39) |
I77V |
probably benign |
Het |
| Tcof1 |
G |
C |
18: 60,962,123 (GRCm39) |
A702G |
possibly damaging |
Het |
| Tdrd3 |
G |
T |
14: 87,709,636 (GRCm39) |
C100F |
probably damaging |
Het |
| Tek |
T |
A |
4: 94,715,953 (GRCm39) |
H458Q |
possibly damaging |
Het |
| Tes |
C |
A |
6: 17,099,743 (GRCm39) |
P246Q |
probably damaging |
Het |
| Tgif1 |
A |
T |
17: 71,156,603 (GRCm39) |
|
probably null |
Het |
| Tlr11 |
A |
T |
14: 50,599,285 (GRCm39) |
N424Y |
probably damaging |
Het |
| Tmc8 |
A |
T |
11: 117,682,953 (GRCm39) |
N626I |
probably damaging |
Het |
| Tmem132c |
T |
A |
5: 127,641,152 (GRCm39) |
*1108K |
probably null |
Het |
| Tnks |
A |
T |
8: 35,340,182 (GRCm39) |
Y479N |
probably benign |
Het |
| Trip12 |
C |
T |
1: 84,738,527 (GRCm39) |
G776D |
probably damaging |
Het |
| Tssk1 |
A |
G |
16: 17,712,311 (GRCm39) |
E32G |
probably benign |
Het |
| Ube2o |
T |
C |
11: 116,434,736 (GRCm39) |
D575G |
probably damaging |
Het |
| Uckl1 |
A |
T |
2: 181,216,460 (GRCm39) |
M16K |
probably damaging |
Het |
| Zfp948 |
A |
T |
17: 21,807,985 (GRCm39) |
E392D |
probably benign |
Het |
| Zmynd8 |
G |
A |
2: 165,684,751 (GRCm39) |
T167I |
probably damaging |
Het |
|
| Other mutations in Mybpc1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00468:Mybpc1
|
APN |
10 |
88,385,124 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL00577:Mybpc1
|
APN |
10 |
88,372,246 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00703:Mybpc1
|
APN |
10 |
88,360,970 (GRCm39) |
splice site |
probably null |
|
|
IGL00964:Mybpc1
|
APN |
10 |
88,391,604 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
IGL01738:Mybpc1
|
APN |
10 |
88,406,507 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01978:Mybpc1
|
APN |
10 |
88,367,632 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02255:Mybpc1
|
APN |
10 |
88,372,290 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02997:Mybpc1
|
APN |
10 |
88,362,235 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0098:Mybpc1
|
UTSW |
10 |
88,365,426 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0240:Mybpc1
|
UTSW |
10 |
88,391,600 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R0240:Mybpc1
|
UTSW |
10 |
88,391,600 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R0449:Mybpc1
|
UTSW |
10 |
88,376,822 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0879:Mybpc1
|
UTSW |
10 |
88,407,378 (GRCm39) |
splice site |
probably benign |
|
|
R1321:Mybpc1
|
UTSW |
10 |
88,406,463 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1321:Mybpc1
|
UTSW |
10 |
88,365,403 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R1562:Mybpc1
|
UTSW |
10 |
88,389,193 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1783:Mybpc1
|
UTSW |
10 |
88,406,430 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1803:Mybpc1
|
UTSW |
10 |
88,389,157 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R1962:Mybpc1
|
UTSW |
10 |
88,384,688 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1972:Mybpc1
|
UTSW |
10 |
88,387,404 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2006:Mybpc1
|
UTSW |
10 |
88,381,921 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2125:Mybpc1
|
UTSW |
10 |
88,409,299 (GRCm39) |
nonsense |
probably null |
|
|
R2129:Mybpc1
|
UTSW |
10 |
88,387,314 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2163:Mybpc1
|
UTSW |
10 |
88,376,804 (GRCm39) |
splice site |
probably benign |
|
|
R2200:Mybpc1
|
UTSW |
10 |
88,391,557 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2219:Mybpc1
|
UTSW |
10 |
88,391,540 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2270:Mybpc1
|
UTSW |
10 |
88,387,269 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2961:Mybpc1
|
UTSW |
10 |
88,367,641 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3767:Mybpc1
|
UTSW |
10 |
88,406,521 (GRCm39) |
splice site |
probably null |
|
|
R4032:Mybpc1
|
UTSW |
10 |
88,365,426 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4226:Mybpc1
|
UTSW |
10 |
88,409,387 (GRCm39) |
nonsense |
probably null |
|
|
R4821:Mybpc1
|
UTSW |
10 |
88,384,727 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4876:Mybpc1
|
UTSW |
10 |
88,372,286 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4876:Mybpc1
|
UTSW |
10 |
88,358,853 (GRCm39) |
missense |
probably benign |
|
|
R4878:Mybpc1
|
UTSW |
10 |
88,387,292 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4910:Mybpc1
|
UTSW |
10 |
88,391,586 (GRCm39) |
nonsense |
probably null |
|
|
R4913:Mybpc1
|
UTSW |
10 |
88,389,116 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4964:Mybpc1
|
UTSW |
10 |
88,391,525 (GRCm39) |
missense |
probably benign |
0.31 |
|
R5023:Mybpc1
|
UTSW |
10 |
88,379,636 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5098:Mybpc1
|
UTSW |
10 |
88,381,926 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5196:Mybpc1
|
UTSW |
10 |
88,372,213 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5344:Mybpc1
|
UTSW |
10 |
88,406,430 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5399:Mybpc1
|
UTSW |
10 |
88,358,876 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5538:Mybpc1
|
UTSW |
10 |
88,381,891 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5808:Mybpc1
|
UTSW |
10 |
88,406,428 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R5970:Mybpc1
|
UTSW |
10 |
88,378,318 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6324:Mybpc1
|
UTSW |
10 |
88,404,481 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R6433:Mybpc1
|
UTSW |
10 |
88,396,217 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6441:Mybpc1
|
UTSW |
10 |
88,389,139 (GRCm39) |
missense |
probably benign |
0.09 |
|
R6648:Mybpc1
|
UTSW |
10 |
88,358,861 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6844:Mybpc1
|
UTSW |
10 |
88,372,243 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R6931:Mybpc1
|
UTSW |
10 |
88,378,192 (GRCm39) |
nonsense |
probably null |
|
|
R6972:Mybpc1
|
UTSW |
10 |
88,396,223 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R6973:Mybpc1
|
UTSW |
10 |
88,396,223 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R6978:Mybpc1
|
UTSW |
10 |
88,358,886 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7007:Mybpc1
|
UTSW |
10 |
88,389,274 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7019:Mybpc1
|
UTSW |
10 |
88,379,581 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7407:Mybpc1
|
UTSW |
10 |
88,385,209 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7442:Mybpc1
|
UTSW |
10 |
88,362,155 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7577:Mybpc1
|
UTSW |
10 |
88,385,187 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7660:Mybpc1
|
UTSW |
10 |
88,384,716 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R7768:Mybpc1
|
UTSW |
10 |
88,378,234 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8171:Mybpc1
|
UTSW |
10 |
88,358,865 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8195:Mybpc1
|
UTSW |
10 |
88,394,553 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R8241:Mybpc1
|
UTSW |
10 |
88,372,286 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8360:Mybpc1
|
UTSW |
10 |
88,409,359 (GRCm39) |
nonsense |
probably null |
|
|
R8494:Mybpc1
|
UTSW |
10 |
88,362,291 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8849:Mybpc1
|
UTSW |
10 |
88,407,447 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8936:Mybpc1
|
UTSW |
10 |
88,394,437 (GRCm39) |
missense |
probably benign |
0.44 |
|
R9031:Mybpc1
|
UTSW |
10 |
88,358,906 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9061:Mybpc1
|
UTSW |
10 |
88,391,501 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9081:Mybpc1
|
UTSW |
10 |
88,389,168 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9172:Mybpc1
|
UTSW |
10 |
88,379,615 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R9323:Mybpc1
|
UTSW |
10 |
88,360,829 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9460:Mybpc1
|
UTSW |
10 |
88,372,197 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9488:Mybpc1
|
UTSW |
10 |
88,379,624 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R9757:Mybpc1
|
UTSW |
10 |
88,372,257 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9796:Mybpc1
|
UTSW |
10 |
88,406,497 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
Z1176:Mybpc1
|
UTSW |
10 |
88,396,189 (GRCm39) |
missense |
probably benign |
|
|
Z1177:Mybpc1
|
UTSW |
10 |
88,409,299 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GACATATGCCCAGAAAGTTCTTCG -3'
(R):5'- TCCGCATGTCAACAAAACTCTG -3'
Sequencing Primer
(F):5'- ATATGCCCAGAAAGTTCTTCGATTCC -3'
(R):5'- ACACAGTAATTGGGAAGGCTTC -3'
|
| Posted On |
2019-12-03 |
Incidental Mutation