Incidental Mutation 'R7818:Sez6'
| ID |
601685 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Sez6
|
| Ensembl Gene |
ENSMUSG00000000632 |
| Gene Name |
seizure related gene 6 |
| Synonyms |
sez-6, D11Bhm177e |
| MMRRC Submission |
045872-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7818 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
11 |
| Chromosomal Location |
77821626-77869874 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 77867728 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Proline to Serine
at position 882
(P882S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000091532
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000000646]
[ENSMUST00000093995]
|
| AlphaFold |
Q7TSK2 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000000646
AA Change: P882S
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000000646
Gene: ENSMUSG00000000632
AA Change: P882S
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
19 |
N/A |
INTRINSIC |
|
low complexity region
|
72 |
85 |
N/A |
INTRINSIC |
|
low complexity region
|
119 |
132 |
N/A |
INTRINSIC |
|
low complexity region
|
223 |
235 |
N/A |
INTRINSIC |
|
CUB
|
241 |
350 |
9.36e-2 |
SMART |
|
CCP
|
354 |
409 |
1.23e-10 |
SMART |
|
CUB
|
413 |
524 |
1.41e-28 |
SMART |
|
CCP
|
529 |
586 |
5.43e-12 |
SMART |
|
CUB
|
590 |
701 |
7.49e-24 |
SMART |
|
CCP
|
707 |
762 |
3.09e-16 |
SMART |
|
CCP
|
768 |
827 |
3.5e-15 |
SMART |
|
CCP
|
835 |
892 |
1.42e-15 |
SMART |
|
transmembrane domain
|
910 |
932 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000093995
AA Change: P882S
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000091532
Gene: ENSMUSG00000000632
AA Change: P882S
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
19 |
N/A |
INTRINSIC |
|
low complexity region
|
72 |
85 |
N/A |
INTRINSIC |
|
low complexity region
|
119 |
132 |
N/A |
INTRINSIC |
|
low complexity region
|
223 |
235 |
N/A |
INTRINSIC |
|
CUB
|
241 |
350 |
9.36e-2 |
SMART |
|
CCP
|
354 |
409 |
1.23e-10 |
SMART |
|
CUB
|
413 |
524 |
1.41e-28 |
SMART |
|
CCP
|
529 |
586 |
5.43e-12 |
SMART |
|
CUB
|
590 |
701 |
7.49e-24 |
SMART |
|
CCP
|
707 |
762 |
3.09e-16 |
SMART |
|
CCP
|
768 |
827 |
3.5e-15 |
SMART |
|
CCP
|
835 |
892 |
1.42e-15 |
SMART |
|
transmembrane domain
|
923 |
945 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000140630
|
| SMART Domains |
Protein: ENSMUSP00000115660
Gene: ENSMUSG00000000632
| Domain | Start | End | E-Value | Type |
|---|
|
CUB
|
29 |
140 |
9.8e-28 |
SMART |
|
CCP
|
157 |
214 |
5.43e-12 |
SMART |
|
Pfam:CUB
|
218 |
278 |
1.6e-11 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000151982
|
| SMART Domains |
Protein: ENSMUSP00000132041
Gene: ENSMUSG00000000632
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
57 |
69 |
N/A |
INTRINSIC |
|
CUB
|
75 |
184 |
9.36e-2 |
SMART |
|
CCP
|
188 |
243 |
1.23e-10 |
SMART |
|
CUB
|
247 |
358 |
8.08e-29 |
SMART |
|
low complexity region
|
379 |
394 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.5%
- 20x: 98.5%
|
| Validation Efficiency |
99% (88/89) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is thought to contain five cysteine-rich motifs that are similar to sushi domains, as well as two domains similar to the amino terminal half of the CUB (for complement C1r/C1s, Uegf, Bmp1) domain. Mutations in this gene have been associated with febrile seizures. [provided by RefSeq, Jul 2016]
PHENOTYPE: Mice homozygous for a null allele exhibit increased short dendrites, decreased excitatory synaptic signaling, resistance to pharmacologically induces seizures, decreased activity and impaired learning and coordination. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 88 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4931429L15Rik |
T |
A |
9: 46,215,519 (GRCm39) |
R342S |
probably benign |
Het |
| Aatk |
C |
T |
11: 119,912,281 (GRCm39) |
V55I |
probably benign |
Het |
| Abhd10 |
T |
A |
16: 45,557,916 (GRCm39) |
I128L |
probably benign |
Het |
| Abraxas1 |
T |
A |
5: 100,954,176 (GRCm39) |
M325L |
probably benign |
Het |
| Adgrb2 |
C |
A |
4: 129,908,353 (GRCm39) |
L1087I |
probably damaging |
Het |
| Adgrb2 |
C |
T |
4: 129,908,762 (GRCm39) |
P1124S |
possibly damaging |
Het |
| Akap9 |
T |
A |
5: 4,063,875 (GRCm39) |
Y1741* |
probably null |
Het |
| Ap1g2 |
A |
T |
14: 55,337,181 (GRCm39) |
V718D |
probably benign |
Het |
| Asph |
A |
T |
4: 9,475,015 (GRCm39) |
M637K |
probably damaging |
Het |
| Atp2c1 |
T |
C |
9: 105,291,956 (GRCm39) |
I869V |
probably benign |
Het |
| C1ra |
G |
A |
6: 124,494,684 (GRCm39) |
E316K |
probably benign |
Het |
| Cacna1e |
T |
C |
1: 154,274,152 (GRCm39) |
D2251G |
probably damaging |
Het |
| Camk2b |
A |
G |
11: 5,927,812 (GRCm39) |
S413P |
probably benign |
Het |
| Casz1 |
G |
A |
4: 149,030,533 (GRCm39) |
C1184Y |
probably damaging |
Het |
| Cbr4 |
G |
A |
8: 61,940,976 (GRCm39) |
V32I |
probably benign |
Het |
| Ccdc166 |
A |
G |
15: 75,852,864 (GRCm39) |
S368P |
possibly damaging |
Het |
| Ccdc170 |
A |
G |
10: 4,499,603 (GRCm39) |
N508S |
probably benign |
Het |
| Ccdc187 |
A |
G |
2: 26,166,186 (GRCm39) |
S748P |
possibly damaging |
Het |
| Cdca8 |
A |
T |
4: 124,820,456 (GRCm39) |
|
probably null |
Het |
| Cep120 |
T |
C |
18: 53,856,175 (GRCm39) |
D414G |
probably benign |
Het |
| Dcp1a |
G |
T |
14: 30,201,678 (GRCm39) |
A34S |
probably damaging |
Het |
| Ddit3 |
C |
T |
10: 127,131,662 (GRCm39) |
T70I |
probably benign |
Het |
| Dlg2 |
C |
G |
7: 91,589,225 (GRCm39) |
A313G |
probably damaging |
Het |
| Dnah9 |
A |
T |
11: 65,916,037 (GRCm39) |
V2305D |
possibly damaging |
Het |
| Dock1 |
T |
A |
7: 134,365,594 (GRCm39) |
D427E |
probably damaging |
Het |
| Dolpp1 |
T |
C |
2: 30,286,503 (GRCm39) |
L141P |
probably benign |
Het |
| Dsc2 |
A |
T |
18: 20,183,189 (GRCm39) |
D76E |
probably damaging |
Het |
| Dusp7 |
C |
A |
9: 106,246,329 (GRCm39) |
N111K |
probably benign |
Het |
| Fam193a |
A |
G |
5: 34,622,997 (GRCm39) |
E1195G |
possibly damaging |
Het |
| Fig4 |
A |
G |
10: 41,139,162 (GRCm39) |
L347P |
probably damaging |
Het |
| Frem1 |
T |
C |
4: 82,932,245 (GRCm39) |
E152G |
probably damaging |
Het |
| Galnt2 |
G |
T |
8: 125,056,527 (GRCm39) |
D234Y |
probably damaging |
Het |
| H1f3 |
C |
T |
13: 23,739,165 (GRCm39) |
|
probably benign |
Het |
| Igkv4-59 |
T |
C |
6: 69,415,475 (GRCm39) |
T27A |
possibly damaging |
Het |
| Ihh |
T |
C |
1: 74,985,804 (GRCm39) |
D227G |
possibly damaging |
Het |
| Il1rap |
T |
A |
16: 26,517,597 (GRCm39) |
C266S |
probably damaging |
Het |
| Iqcf4 |
A |
T |
9: 106,447,738 (GRCm39) |
L57* |
probably null |
Het |
| Kif2b |
A |
G |
11: 91,466,952 (GRCm39) |
S444P |
probably damaging |
Het |
| Lmf1 |
T |
G |
17: 25,881,565 (GRCm39) |
I538S |
probably benign |
Het |
| Mical2 |
A |
G |
7: 111,944,514 (GRCm39) |
Y948C |
probably damaging |
Het |
| Mr1 |
G |
A |
1: 155,006,382 (GRCm39) |
Q322* |
probably null |
Het |
| Mroh2a |
T |
C |
1: 88,162,334 (GRCm39) |
|
probably null |
Het |
| Mup6 |
A |
G |
4: 60,004,884 (GRCm39) |
T100A |
probably benign |
Het |
| Mybpc1 |
T |
A |
10: 88,394,529 (GRCm39) |
D266V |
probably damaging |
Het |
| Myocos |
T |
C |
1: 162,475,063 (GRCm39) |
N48S |
unknown |
Het |
| Naf1 |
G |
A |
8: 67,342,028 (GRCm39) |
G551E |
probably damaging |
Het |
| Nrarp |
A |
G |
2: 25,071,250 (GRCm39) |
N43S |
possibly damaging |
Het |
| Or4a80 |
A |
G |
2: 89,582,288 (GRCm39) |
S295P |
possibly damaging |
Het |
| Or5p52 |
G |
A |
7: 107,502,230 (GRCm39) |
C102Y |
probably benign |
Het |
| Or7a40 |
A |
C |
16: 16,491,437 (GRCm39) |
M136R |
probably damaging |
Het |
| Or7g19 |
T |
A |
9: 18,856,305 (GRCm39) |
Y120* |
probably null |
Het |
| Or8b57 |
T |
A |
9: 40,004,008 (GRCm39) |
M85L |
probably damaging |
Het |
| Padi3 |
T |
A |
4: 140,525,453 (GRCm39) |
T177S |
possibly damaging |
Het |
| Pde3b |
A |
G |
7: 114,090,675 (GRCm39) |
M305V |
probably damaging |
Het |
| Pde6a |
T |
A |
18: 61,414,580 (GRCm39) |
|
probably null |
Het |
| Plscr4 |
C |
T |
9: 92,372,843 (GRCm39) |
R322* |
probably null |
Het |
| Prph |
A |
G |
15: 98,955,753 (GRCm39) |
T446A |
probably damaging |
Het |
| Pwwp2b |
T |
C |
7: 138,835,240 (GRCm39) |
V227A |
probably benign |
Het |
| Rev3l |
T |
C |
10: 39,699,898 (GRCm39) |
I1465T |
possibly damaging |
Het |
| Rin1 |
A |
G |
19: 5,102,219 (GRCm39) |
S243G |
probably benign |
Het |
| Ripor3 |
A |
T |
2: 167,831,346 (GRCm39) |
I485N |
probably benign |
Het |
| Rnpc3 |
G |
T |
3: 113,423,600 (GRCm39) |
P35Q |
probably damaging |
Het |
| Sbpl |
G |
T |
17: 24,172,236 (GRCm39) |
Q228K |
unknown |
Het |
| Scn11a |
A |
C |
9: 119,613,177 (GRCm39) |
N804K |
probably damaging |
Het |
| Selenoo |
A |
G |
15: 88,981,019 (GRCm39) |
T453A |
probably damaging |
Het |
| Skint5 |
C |
T |
4: 113,799,923 (GRCm39) |
R82H |
possibly damaging |
Het |
| Slc18a2 |
A |
C |
19: 59,251,593 (GRCm39) |
T115P |
probably benign |
Het |
| Slc1a2 |
A |
G |
2: 102,574,301 (GRCm39) |
D237G |
probably benign |
Het |
| Spidr |
T |
C |
16: 15,932,729 (GRCm39) |
S184G |
probably damaging |
Het |
| Stag3 |
A |
T |
5: 138,299,705 (GRCm39) |
Q872L |
probably benign |
Het |
| Suds3 |
T |
C |
5: 117,253,814 (GRCm39) |
|
probably benign |
Het |
| Sv2c |
T |
A |
13: 96,123,328 (GRCm39) |
K382* |
probably null |
Het |
| Taf2 |
T |
C |
15: 54,929,326 (GRCm39) |
I77V |
probably benign |
Het |
| Tcof1 |
G |
C |
18: 60,962,123 (GRCm39) |
A702G |
possibly damaging |
Het |
| Tdrd3 |
G |
T |
14: 87,709,636 (GRCm39) |
C100F |
probably damaging |
Het |
| Tek |
T |
A |
4: 94,715,953 (GRCm39) |
H458Q |
possibly damaging |
Het |
| Tes |
C |
A |
6: 17,099,743 (GRCm39) |
P246Q |
probably damaging |
Het |
| Tgif1 |
A |
T |
17: 71,156,603 (GRCm39) |
|
probably null |
Het |
| Tlr11 |
A |
T |
14: 50,599,285 (GRCm39) |
N424Y |
probably damaging |
Het |
| Tmc8 |
A |
T |
11: 117,682,953 (GRCm39) |
N626I |
probably damaging |
Het |
| Tmem132c |
T |
A |
5: 127,641,152 (GRCm39) |
*1108K |
probably null |
Het |
| Tnks |
A |
T |
8: 35,340,182 (GRCm39) |
Y479N |
probably benign |
Het |
| Trip12 |
C |
T |
1: 84,738,527 (GRCm39) |
G776D |
probably damaging |
Het |
| Tssk1 |
A |
G |
16: 17,712,311 (GRCm39) |
E32G |
probably benign |
Het |
| Ube2o |
T |
C |
11: 116,434,736 (GRCm39) |
D575G |
probably damaging |
Het |
| Uckl1 |
A |
T |
2: 181,216,460 (GRCm39) |
M16K |
probably damaging |
Het |
| Zfp948 |
A |
T |
17: 21,807,985 (GRCm39) |
E392D |
probably benign |
Het |
| Zmynd8 |
G |
A |
2: 165,684,751 (GRCm39) |
T167I |
probably damaging |
Het |
|
| Other mutations in Sez6 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01125:Sez6
|
APN |
11 |
77,868,115 (GRCm39) |
splice site |
probably benign |
|
|
IGL01142:Sez6
|
APN |
11 |
77,864,642 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02252:Sez6
|
APN |
11 |
77,865,339 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02332:Sez6
|
APN |
11 |
77,845,568 (GRCm39) |
splice site |
probably benign |
|
|
IGL02366:Sez6
|
APN |
11 |
77,867,708 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02479:Sez6
|
APN |
11 |
77,868,852 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
IGL02963:Sez6
|
APN |
11 |
77,853,775 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
velum
|
UTSW |
11 |
77,865,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0054:Sez6
|
UTSW |
11 |
77,844,699 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0054:Sez6
|
UTSW |
11 |
77,844,699 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0089:Sez6
|
UTSW |
11 |
77,865,170 (GRCm39) |
splice site |
probably benign |
|
|
R0485:Sez6
|
UTSW |
11 |
77,844,639 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0598:Sez6
|
UTSW |
11 |
77,868,647 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R0729:Sez6
|
UTSW |
11 |
77,867,411 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1117:Sez6
|
UTSW |
11 |
77,865,340 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1199:Sez6
|
UTSW |
11 |
77,844,711 (GRCm39) |
missense |
probably benign |
|
|
R1534:Sez6
|
UTSW |
11 |
77,853,871 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1835:Sez6
|
UTSW |
11 |
77,844,329 (GRCm39) |
missense |
probably benign |
|
|
R1840:Sez6
|
UTSW |
11 |
77,844,543 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R1929:Sez6
|
UTSW |
11 |
77,863,758 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1970:Sez6
|
UTSW |
11 |
77,844,894 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3156:Sez6
|
UTSW |
11 |
77,844,605 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R3930:Sez6
|
UTSW |
11 |
77,867,708 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3931:Sez6
|
UTSW |
11 |
77,867,708 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4894:Sez6
|
UTSW |
11 |
77,866,086 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4904:Sez6
|
UTSW |
11 |
77,866,080 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5026:Sez6
|
UTSW |
11 |
77,859,815 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5040:Sez6
|
UTSW |
11 |
77,859,915 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5057:Sez6
|
UTSW |
11 |
77,863,979 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5093:Sez6
|
UTSW |
11 |
77,867,388 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R5640:Sez6
|
UTSW |
11 |
77,864,585 (GRCm39) |
intron |
probably benign |
|
|
R6013:Sez6
|
UTSW |
11 |
77,864,623 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6126:Sez6
|
UTSW |
11 |
77,864,630 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6153:Sez6
|
UTSW |
11 |
77,868,648 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6279:Sez6
|
UTSW |
11 |
77,867,367 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R6300:Sez6
|
UTSW |
11 |
77,867,367 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R6475:Sez6
|
UTSW |
11 |
77,864,670 (GRCm39) |
|
|
|
|
R6722:Sez6
|
UTSW |
11 |
77,844,528 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6897:Sez6
|
UTSW |
11 |
77,844,385 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6910:Sez6
|
UTSW |
11 |
77,844,695 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R7012:Sez6
|
UTSW |
11 |
77,868,621 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7233:Sez6
|
UTSW |
11 |
77,863,963 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7265:Sez6
|
UTSW |
11 |
77,853,691 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7289:Sez6
|
UTSW |
11 |
77,865,149 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R7405:Sez6
|
UTSW |
11 |
77,853,717 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7408:Sez6
|
UTSW |
11 |
77,844,356 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7485:Sez6
|
UTSW |
11 |
77,864,711 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7592:Sez6
|
UTSW |
11 |
77,868,876 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7778:Sez6
|
UTSW |
11 |
77,865,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7793:Sez6
|
UTSW |
11 |
77,868,426 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7824:Sez6
|
UTSW |
11 |
77,865,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7980:Sez6
|
UTSW |
11 |
77,844,668 (GRCm39) |
missense |
probably benign |
0.34 |
|
R8008:Sez6
|
UTSW |
11 |
77,864,082 (GRCm39) |
nonsense |
probably null |
|
|
R8840:Sez6
|
UTSW |
11 |
77,867,313 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8947:Sez6
|
UTSW |
11 |
77,844,353 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8973:Sez6
|
UTSW |
11 |
77,865,397 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9040:Sez6
|
UTSW |
11 |
77,864,762 (GRCm39) |
missense |
probably benign |
|
|
R9081:Sez6
|
UTSW |
11 |
77,865,121 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9082:Sez6
|
UTSW |
11 |
77,865,121 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9092:Sez6
|
UTSW |
11 |
77,865,121 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9094:Sez6
|
UTSW |
11 |
77,865,121 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9095:Sez6
|
UTSW |
11 |
77,865,121 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9097:Sez6
|
UTSW |
11 |
77,865,121 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9169:Sez6
|
UTSW |
11 |
77,868,473 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9513:Sez6
|
UTSW |
11 |
77,865,409 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9630:Sez6
|
UTSW |
11 |
77,865,121 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9632:Sez6
|
UTSW |
11 |
77,865,121 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9646:Sez6
|
UTSW |
11 |
77,867,632 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9709:Sez6
|
UTSW |
11 |
77,865,121 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
X0013:Sez6
|
UTSW |
11 |
77,845,606 (GRCm39) |
missense |
probably benign |
0.01 |
|
X0067:Sez6
|
UTSW |
11 |
77,865,264 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
Z1088:Sez6
|
UTSW |
11 |
77,864,023 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
| Predicted Primers |
PCR Primer
(F):5'- AAACCTGACACCTCGATTGC -3'
(R):5'- ACTCCTGCAGTGTCTTGGTG -3'
Sequencing Primer
(F):5'- GACACCTCGATTGCTGCCTG -3'
(R):5'- TGGTGATGTTAAATCAGAGACTAGC -3'
|
| Posted On |
2019-12-03 |
Incidental Mutation