Incidental Mutation 'R7818:Dsc2'
| ID |
601708 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dsc2
|
| Ensembl Gene |
ENSMUSG00000024331 |
| Gene Name |
desmocollin 2 |
| Synonyms |
Dsc2a, Dsc2b |
| MMRRC Submission |
045872-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7818 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
18 |
| Chromosomal Location |
20163690-20192611 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 20183189 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glutamic Acid
at position 76
(D76E)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000074702
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000039247]
[ENSMUST00000075214]
[ENSMUST00000128464]
|
| AlphaFold |
P55292 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000039247
AA Change: D76E
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000042905
Gene: ENSMUSG00000024331
AA Change: D76E
| Domain | Start | End | E-Value | Type |
|---|
|
Cadherin_pro
|
31 |
113 |
2.82e-37 |
SMART |
|
CA
|
156 |
241 |
4.66e-11 |
SMART |
|
CA
|
265 |
353 |
1.87e-24 |
SMART |
|
low complexity region
|
358 |
372 |
N/A |
INTRINSIC |
|
CA
|
376 |
470 |
1.27e-12 |
SMART |
|
CA
|
493 |
575 |
4.14e-17 |
SMART |
|
CA
|
594 |
676 |
1.49e-1 |
SMART |
|
transmembrane domain
|
696 |
718 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000075214
AA Change: D76E
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000074702
Gene: ENSMUSG00000024331
AA Change: D76E
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
28 |
N/A |
INTRINSIC |
|
Cadherin_pro
|
31 |
113 |
2.82e-37 |
SMART |
|
CA
|
156 |
241 |
4.66e-11 |
SMART |
|
CA
|
265 |
353 |
1.87e-24 |
SMART |
|
low complexity region
|
358 |
372 |
N/A |
INTRINSIC |
|
CA
|
376 |
470 |
1.27e-12 |
SMART |
|
CA
|
493 |
575 |
4.14e-17 |
SMART |
|
CA
|
594 |
676 |
1.49e-1 |
SMART |
|
transmembrane domain
|
696 |
718 |
N/A |
INTRINSIC |
|
Pfam:Cadherin_C
|
730 |
901 |
3.7e-9 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000128464
AA Change: D76E
PolyPhen 2
Score 0.983 (Sensitivity: 0.75; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000123010
Gene: ENSMUSG00000024331
AA Change: D76E
| Domain | Start | End | E-Value | Type |
|---|
|
Cadherin_pro
|
31 |
113 |
2.82e-37 |
SMART |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.5%
- 20x: 98.5%
|
| Validation Efficiency |
99% (88/89) |
| MGI Phenotype |
FUNCTION: This gene encodes a member of the desmocollin protein subfamily. Desmocollins are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
|
| Allele List at MGI |
All alleles(2) : Targeted, other(2) |
| Other mutations in this stock |
Total: 88 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4931429L15Rik |
T |
A |
9: 46,215,519 (GRCm39) |
R342S |
probably benign |
Het |
| Aatk |
C |
T |
11: 119,912,281 (GRCm39) |
V55I |
probably benign |
Het |
| Abhd10 |
T |
A |
16: 45,557,916 (GRCm39) |
I128L |
probably benign |
Het |
| Abraxas1 |
T |
A |
5: 100,954,176 (GRCm39) |
M325L |
probably benign |
Het |
| Adgrb2 |
C |
A |
4: 129,908,353 (GRCm39) |
L1087I |
probably damaging |
Het |
| Adgrb2 |
C |
T |
4: 129,908,762 (GRCm39) |
P1124S |
possibly damaging |
Het |
| Akap9 |
T |
A |
5: 4,063,875 (GRCm39) |
Y1741* |
probably null |
Het |
| Ap1g2 |
A |
T |
14: 55,337,181 (GRCm39) |
V718D |
probably benign |
Het |
| Asph |
A |
T |
4: 9,475,015 (GRCm39) |
M637K |
probably damaging |
Het |
| Atp2c1 |
T |
C |
9: 105,291,956 (GRCm39) |
I869V |
probably benign |
Het |
| C1ra |
G |
A |
6: 124,494,684 (GRCm39) |
E316K |
probably benign |
Het |
| Cacna1e |
T |
C |
1: 154,274,152 (GRCm39) |
D2251G |
probably damaging |
Het |
| Camk2b |
A |
G |
11: 5,927,812 (GRCm39) |
S413P |
probably benign |
Het |
| Casz1 |
G |
A |
4: 149,030,533 (GRCm39) |
C1184Y |
probably damaging |
Het |
| Cbr4 |
G |
A |
8: 61,940,976 (GRCm39) |
V32I |
probably benign |
Het |
| Ccdc166 |
A |
G |
15: 75,852,864 (GRCm39) |
S368P |
possibly damaging |
Het |
| Ccdc170 |
A |
G |
10: 4,499,603 (GRCm39) |
N508S |
probably benign |
Het |
| Ccdc187 |
A |
G |
2: 26,166,186 (GRCm39) |
S748P |
possibly damaging |
Het |
| Cdca8 |
A |
T |
4: 124,820,456 (GRCm39) |
|
probably null |
Het |
| Cep120 |
T |
C |
18: 53,856,175 (GRCm39) |
D414G |
probably benign |
Het |
| Dcp1a |
G |
T |
14: 30,201,678 (GRCm39) |
A34S |
probably damaging |
Het |
| Ddit3 |
C |
T |
10: 127,131,662 (GRCm39) |
T70I |
probably benign |
Het |
| Dlg2 |
C |
G |
7: 91,589,225 (GRCm39) |
A313G |
probably damaging |
Het |
| Dnah9 |
A |
T |
11: 65,916,037 (GRCm39) |
V2305D |
possibly damaging |
Het |
| Dock1 |
T |
A |
7: 134,365,594 (GRCm39) |
D427E |
probably damaging |
Het |
| Dolpp1 |
T |
C |
2: 30,286,503 (GRCm39) |
L141P |
probably benign |
Het |
| Dusp7 |
C |
A |
9: 106,246,329 (GRCm39) |
N111K |
probably benign |
Het |
| Fam193a |
A |
G |
5: 34,622,997 (GRCm39) |
E1195G |
possibly damaging |
Het |
| Fig4 |
A |
G |
10: 41,139,162 (GRCm39) |
L347P |
probably damaging |
Het |
| Frem1 |
T |
C |
4: 82,932,245 (GRCm39) |
E152G |
probably damaging |
Het |
| Galnt2 |
G |
T |
8: 125,056,527 (GRCm39) |
D234Y |
probably damaging |
Het |
| H1f3 |
C |
T |
13: 23,739,165 (GRCm39) |
|
probably benign |
Het |
| Igkv4-59 |
T |
C |
6: 69,415,475 (GRCm39) |
T27A |
possibly damaging |
Het |
| Ihh |
T |
C |
1: 74,985,804 (GRCm39) |
D227G |
possibly damaging |
Het |
| Il1rap |
T |
A |
16: 26,517,597 (GRCm39) |
C266S |
probably damaging |
Het |
| Iqcf4 |
A |
T |
9: 106,447,738 (GRCm39) |
L57* |
probably null |
Het |
| Kif2b |
A |
G |
11: 91,466,952 (GRCm39) |
S444P |
probably damaging |
Het |
| Lmf1 |
T |
G |
17: 25,881,565 (GRCm39) |
I538S |
probably benign |
Het |
| Mical2 |
A |
G |
7: 111,944,514 (GRCm39) |
Y948C |
probably damaging |
Het |
| Mr1 |
G |
A |
1: 155,006,382 (GRCm39) |
Q322* |
probably null |
Het |
| Mroh2a |
T |
C |
1: 88,162,334 (GRCm39) |
|
probably null |
Het |
| Mup6 |
A |
G |
4: 60,004,884 (GRCm39) |
T100A |
probably benign |
Het |
| Mybpc1 |
T |
A |
10: 88,394,529 (GRCm39) |
D266V |
probably damaging |
Het |
| Myocos |
T |
C |
1: 162,475,063 (GRCm39) |
N48S |
unknown |
Het |
| Naf1 |
G |
A |
8: 67,342,028 (GRCm39) |
G551E |
probably damaging |
Het |
| Nrarp |
A |
G |
2: 25,071,250 (GRCm39) |
N43S |
possibly damaging |
Het |
| Or4a80 |
A |
G |
2: 89,582,288 (GRCm39) |
S295P |
possibly damaging |
Het |
| Or5p52 |
G |
A |
7: 107,502,230 (GRCm39) |
C102Y |
probably benign |
Het |
| Or7a40 |
A |
C |
16: 16,491,437 (GRCm39) |
M136R |
probably damaging |
Het |
| Or7g19 |
T |
A |
9: 18,856,305 (GRCm39) |
Y120* |
probably null |
Het |
| Or8b57 |
T |
A |
9: 40,004,008 (GRCm39) |
M85L |
probably damaging |
Het |
| Padi3 |
T |
A |
4: 140,525,453 (GRCm39) |
T177S |
possibly damaging |
Het |
| Pde3b |
A |
G |
7: 114,090,675 (GRCm39) |
M305V |
probably damaging |
Het |
| Pde6a |
T |
A |
18: 61,414,580 (GRCm39) |
|
probably null |
Het |
| Plscr4 |
C |
T |
9: 92,372,843 (GRCm39) |
R322* |
probably null |
Het |
| Prph |
A |
G |
15: 98,955,753 (GRCm39) |
T446A |
probably damaging |
Het |
| Pwwp2b |
T |
C |
7: 138,835,240 (GRCm39) |
V227A |
probably benign |
Het |
| Rev3l |
T |
C |
10: 39,699,898 (GRCm39) |
I1465T |
possibly damaging |
Het |
| Rin1 |
A |
G |
19: 5,102,219 (GRCm39) |
S243G |
probably benign |
Het |
| Ripor3 |
A |
T |
2: 167,831,346 (GRCm39) |
I485N |
probably benign |
Het |
| Rnpc3 |
G |
T |
3: 113,423,600 (GRCm39) |
P35Q |
probably damaging |
Het |
| Sbpl |
G |
T |
17: 24,172,236 (GRCm39) |
Q228K |
unknown |
Het |
| Scn11a |
A |
C |
9: 119,613,177 (GRCm39) |
N804K |
probably damaging |
Het |
| Selenoo |
A |
G |
15: 88,981,019 (GRCm39) |
T453A |
probably damaging |
Het |
| Sez6 |
C |
T |
11: 77,867,728 (GRCm39) |
P882S |
probably damaging |
Het |
| Skint5 |
C |
T |
4: 113,799,923 (GRCm39) |
R82H |
possibly damaging |
Het |
| Slc18a2 |
A |
C |
19: 59,251,593 (GRCm39) |
T115P |
probably benign |
Het |
| Slc1a2 |
A |
G |
2: 102,574,301 (GRCm39) |
D237G |
probably benign |
Het |
| Spidr |
T |
C |
16: 15,932,729 (GRCm39) |
S184G |
probably damaging |
Het |
| Stag3 |
A |
T |
5: 138,299,705 (GRCm39) |
Q872L |
probably benign |
Het |
| Suds3 |
T |
C |
5: 117,253,814 (GRCm39) |
|
probably benign |
Het |
| Sv2c |
T |
A |
13: 96,123,328 (GRCm39) |
K382* |
probably null |
Het |
| Taf2 |
T |
C |
15: 54,929,326 (GRCm39) |
I77V |
probably benign |
Het |
| Tcof1 |
G |
C |
18: 60,962,123 (GRCm39) |
A702G |
possibly damaging |
Het |
| Tdrd3 |
G |
T |
14: 87,709,636 (GRCm39) |
C100F |
probably damaging |
Het |
| Tek |
T |
A |
4: 94,715,953 (GRCm39) |
H458Q |
possibly damaging |
Het |
| Tes |
C |
A |
6: 17,099,743 (GRCm39) |
P246Q |
probably damaging |
Het |
| Tgif1 |
A |
T |
17: 71,156,603 (GRCm39) |
|
probably null |
Het |
| Tlr11 |
A |
T |
14: 50,599,285 (GRCm39) |
N424Y |
probably damaging |
Het |
| Tmc8 |
A |
T |
11: 117,682,953 (GRCm39) |
N626I |
probably damaging |
Het |
| Tmem132c |
T |
A |
5: 127,641,152 (GRCm39) |
*1108K |
probably null |
Het |
| Tnks |
A |
T |
8: 35,340,182 (GRCm39) |
Y479N |
probably benign |
Het |
| Trip12 |
C |
T |
1: 84,738,527 (GRCm39) |
G776D |
probably damaging |
Het |
| Tssk1 |
A |
G |
16: 17,712,311 (GRCm39) |
E32G |
probably benign |
Het |
| Ube2o |
T |
C |
11: 116,434,736 (GRCm39) |
D575G |
probably damaging |
Het |
| Uckl1 |
A |
T |
2: 181,216,460 (GRCm39) |
M16K |
probably damaging |
Het |
| Zfp948 |
A |
T |
17: 21,807,985 (GRCm39) |
E392D |
probably benign |
Het |
| Zmynd8 |
G |
A |
2: 165,684,751 (GRCm39) |
T167I |
probably damaging |
Het |
|
| Other mutations in Dsc2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00802:Dsc2
|
APN |
18 |
20,174,854 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL00826:Dsc2
|
APN |
18 |
20,168,372 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00852:Dsc2
|
APN |
18 |
20,167,740 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01082:Dsc2
|
APN |
18 |
20,176,849 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01328:Dsc2
|
APN |
18 |
20,181,343 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01338:Dsc2
|
APN |
18 |
20,180,214 (GRCm39) |
missense |
probably benign |
0.19 |
|
IGL01727:Dsc2
|
APN |
18 |
20,171,257 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01766:Dsc2
|
APN |
18 |
20,179,399 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
IGL02228:Dsc2
|
APN |
18 |
20,176,790 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02560:Dsc2
|
APN |
18 |
20,178,596 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02794:Dsc2
|
APN |
18 |
20,174,788 (GRCm39) |
missense |
probably damaging |
1.00 |
|
3-1:Dsc2
|
UTSW |
18 |
20,180,136 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
PIT4305001:Dsc2
|
UTSW |
18 |
20,179,300 (GRCm39) |
missense |
probably damaging |
0.96 |
|
PIT4431001:Dsc2
|
UTSW |
18 |
20,179,334 (GRCm39) |
nonsense |
probably null |
|
|
R0288:Dsc2
|
UTSW |
18 |
20,166,177 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0542:Dsc2
|
UTSW |
18 |
20,184,283 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0562:Dsc2
|
UTSW |
18 |
20,174,594 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0697:Dsc2
|
UTSW |
18 |
20,174,509 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0940:Dsc2
|
UTSW |
18 |
20,183,116 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1081:Dsc2
|
UTSW |
18 |
20,166,352 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1140:Dsc2
|
UTSW |
18 |
20,165,269 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1515:Dsc2
|
UTSW |
18 |
20,178,622 (GRCm39) |
missense |
probably benign |
0.40 |
|
R1515:Dsc2
|
UTSW |
18 |
20,167,758 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1558:Dsc2
|
UTSW |
18 |
20,183,208 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1654:Dsc2
|
UTSW |
18 |
20,179,303 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2061:Dsc2
|
UTSW |
18 |
20,165,456 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R2089:Dsc2
|
UTSW |
18 |
20,166,351 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R2091:Dsc2
|
UTSW |
18 |
20,166,351 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R2091:Dsc2
|
UTSW |
18 |
20,166,351 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R2172:Dsc2
|
UTSW |
18 |
20,178,559 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2247:Dsc2
|
UTSW |
18 |
20,168,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2472:Dsc2
|
UTSW |
18 |
20,178,526 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2927:Dsc2
|
UTSW |
18 |
20,178,558 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3611:Dsc2
|
UTSW |
18 |
20,165,408 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3961:Dsc2
|
UTSW |
18 |
20,184,284 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3963:Dsc2
|
UTSW |
18 |
20,184,284 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4353:Dsc2
|
UTSW |
18 |
20,183,125 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4362:Dsc2
|
UTSW |
18 |
20,183,214 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4612:Dsc2
|
UTSW |
18 |
20,174,876 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4613:Dsc2
|
UTSW |
18 |
20,174,876 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4752:Dsc2
|
UTSW |
18 |
20,171,279 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4946:Dsc2
|
UTSW |
18 |
20,183,214 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5056:Dsc2
|
UTSW |
18 |
20,183,199 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5267:Dsc2
|
UTSW |
18 |
20,167,640 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5445:Dsc2
|
UTSW |
18 |
20,168,360 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R5507:Dsc2
|
UTSW |
18 |
20,179,336 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5575:Dsc2
|
UTSW |
18 |
20,168,447 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5781:Dsc2
|
UTSW |
18 |
20,165,567 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6102:Dsc2
|
UTSW |
18 |
20,180,165 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6129:Dsc2
|
UTSW |
18 |
20,178,487 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6362:Dsc2
|
UTSW |
18 |
20,168,520 (GRCm39) |
nonsense |
probably null |
|
|
R6433:Dsc2
|
UTSW |
18 |
20,184,232 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6513:Dsc2
|
UTSW |
18 |
20,179,295 (GRCm39) |
missense |
probably benign |
|
|
R6615:Dsc2
|
UTSW |
18 |
20,165,576 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R6619:Dsc2
|
UTSW |
18 |
20,165,335 (GRCm39) |
missense |
probably benign |
0.22 |
|
R6665:Dsc2
|
UTSW |
18 |
20,183,205 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6961:Dsc2
|
UTSW |
18 |
20,171,279 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7179:Dsc2
|
UTSW |
18 |
20,168,332 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7275:Dsc2
|
UTSW |
18 |
20,184,236 (GRCm39) |
nonsense |
probably null |
|
|
R7352:Dsc2
|
UTSW |
18 |
20,168,392 (GRCm39) |
missense |
probably benign |
0.39 |
|
R7386:Dsc2
|
UTSW |
18 |
20,174,983 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R7496:Dsc2
|
UTSW |
18 |
20,168,451 (GRCm39) |
nonsense |
probably null |
|
|
R7510:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R7580:Dsc2
|
UTSW |
18 |
20,183,130 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7718:Dsc2
|
UTSW |
18 |
20,174,835 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7733:Dsc2
|
UTSW |
18 |
20,181,373 (GRCm39) |
missense |
probably benign |
0.16 |
|
R7733:Dsc2
|
UTSW |
18 |
20,181,372 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7852:Dsc2
|
UTSW |
18 |
20,179,342 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R7998:Dsc2
|
UTSW |
18 |
20,167,720 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R8029:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8030:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8031:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8032:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8059:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8060:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8061:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8062:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8063:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8082:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8090:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8114:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8115:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8116:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8117:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8118:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8328:Dsc2
|
UTSW |
18 |
20,165,576 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R8545:Dsc2
|
UTSW |
18 |
20,167,722 (GRCm39) |
nonsense |
probably null |
|
|
R9005:Dsc2
|
UTSW |
18 |
20,171,151 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9017:Dsc2
|
UTSW |
18 |
20,176,968 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9111:Dsc2
|
UTSW |
18 |
20,167,764 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9396:Dsc2
|
UTSW |
18 |
20,174,773 (GRCm39) |
nonsense |
probably null |
|
|
R9487:Dsc2
|
UTSW |
18 |
20,180,276 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9663:Dsc2
|
UTSW |
18 |
20,171,205 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Dsc2
|
UTSW |
18 |
20,179,361 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Z1176:Dsc2
|
UTSW |
18 |
20,168,356 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGTCAGTTAGCCCTAAAGAAACAC -3'
(R):5'- TCACATGCCTTTATTTCAGGACAC -3'
Sequencing Primer
(F):5'- CCAATTACACTCCATGCATATCATC -3'
(R):5'- CATGCCTTTATTTCAGGACACATATC -3'
|
| Posted On |
2019-12-03 |
Incidental Mutation