|Institutional Source||Beutler Lab|
|Gene Name||solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1|
|Is this an essential gene?||Probably non essential (E-score: 0.069)|
|Stock #||RF006 (G1)|
|Chromosomal Location||135348029-135397827 bp(+) (GRCm38)|
|Type of Mutation||small deletion (10 aa in frame mutation)|
|DNA Base Change (assembly)||CGAAGGAACCAGAAAGGAAGGAACCAGAAAGGAAGGAACCAGAAAGGAAGGAACCAGAAAGGAAGGAACCAGAAAGGAAGG to CGAAGGAACCAGAAAGGAAGGAACCAGAAAGGAAGGAACCAGAAAGGAAGG at 135357542 bp (GRCm38)|
|Amino Acid Change|
|Ref Sequence||ENSEMBL: ENSMUSP00000124452 (fasta)|
|Gene Model||predicted gene model for transcript(s): [ENSMUST00000078568] [ENSMUST00000159658]|
|AlphaFold||no structure available at present|
|Coding Region Coverage||
|Validation Efficiency||97% (36/37)|
|MGI Phenotype||FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a sodium/hydrogen exchanger and transmembrane protein. Highly conserved orthologs of this gene have been found in other mammalian species. The expression of this gene may be limited to testis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]|
|Allele List at MGI|
|Other mutations in this stock||
|Other mutations in Slc9b1||
(F):5'- CGGGTGCATTAATATGGGGC -3'
(R):5'- GGAGGACAGTAACTATTTGTCCC -3'
(F):5'- AGGGCATCGGATTCCATTAC -3'
(R):5'- GACAGTAACTATTTGTCCCTCTCTTC -3'