Incidental Mutation 'RF008:Phldb2'
| ID |
603011 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Phldb2
|
| Ensembl Gene |
ENSMUSG00000033149 |
| Gene Name |
pleckstrin homology like domain, family B, member 2 |
| Synonyms |
LL5b, C820004H04Rik, LL5beta |
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
RF008 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
16 |
| Chromosomal Location |
45566606-45773961 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 45583337 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Glycine
at position 1054
(S1054G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000075672
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000036355]
[ENSMUST00000076333]
[ENSMUST00000134802]
|
| AlphaFold |
Q8K1N2 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000036355
AA Change: S1001G
PolyPhen 2
Score 0.995 (Sensitivity: 0.68; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000046496
Gene: ENSMUSG00000033149
AA Change: S1001G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
267 |
283 |
N/A |
INTRINSIC |
|
low complexity region
|
426 |
447 |
N/A |
INTRINSIC |
|
coiled coil region
|
580 |
692 |
N/A |
INTRINSIC |
|
coiled coil region
|
724 |
800 |
N/A |
INTRINSIC |
|
coiled coil region
|
1027 |
1097 |
N/A |
INTRINSIC |
|
PH
|
1140 |
1244 |
6.45e-17 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000076333
AA Change: S1054G
PolyPhen 2
Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000075672
Gene: ENSMUSG00000033149
AA Change: S1054G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
267 |
283 |
N/A |
INTRINSIC |
|
low complexity region
|
426 |
447 |
N/A |
INTRINSIC |
|
coiled coil region
|
580 |
692 |
N/A |
INTRINSIC |
|
coiled coil region
|
724 |
800 |
N/A |
INTRINSIC |
|
low complexity region
|
901 |
913 |
N/A |
INTRINSIC |
|
coiled coil region
|
1080 |
1150 |
N/A |
INTRINSIC |
|
PH
|
1193 |
1297 |
6.45e-17 |
SMART |
|
| Predicted Effect |
|
| SMART Domains |
Protein: ENSMUSP00000119718
Gene: ENSMUSG00000033149
AA Change: S316G
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
1 |
55 |
N/A |
INTRINSIC |
|
coiled coil region
|
87 |
163 |
N/A |
INTRINSIC |
|
coiled coil region
|
342 |
412 |
N/A |
INTRINSIC |
|
PH
|
456 |
560 |
6.45e-17 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000134802
AA Change: S1046G
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000123284
Gene: ENSMUSG00000033149
AA Change: S1046G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
20 |
28 |
N/A |
INTRINSIC |
|
low complexity region
|
312 |
328 |
N/A |
INTRINSIC |
|
low complexity region
|
471 |
492 |
N/A |
INTRINSIC |
|
coiled coil region
|
625 |
737 |
N/A |
INTRINSIC |
|
coiled coil region
|
769 |
845 |
N/A |
INTRINSIC |
|
coiled coil region
|
1072 |
1131 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 99.8%
- 3x: 99.7%
- 10x: 99.4%
- 20x: 98.7%
|
| Validation Efficiency |
100% (45/45) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 70 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abi3bp |
CCACGACC |
CCACGACCACGACC |
16: 56,447,952 (GRCm39) |
|
probably benign |
Het |
| Acan |
T |
G |
7: 78,742,148 (GRCm39) |
V515G |
possibly damaging |
Het |
| Acap3 |
TGG |
TGGACTGCTGCATCCAGG |
4: 155,989,555 (GRCm39) |
|
probably benign |
Het |
| AI837181 |
G |
GGCT |
19: 5,475,266 (GRCm39) |
|
probably benign |
Het |
| Ankhd1 |
GGCGGC |
GGCGGCAGCGGC |
18: 36,693,977 (GRCm39) |
|
probably benign |
Het |
| Anks1b |
G |
A |
10: 89,869,087 (GRCm39) |
G49D |
probably damaging |
Het |
| Arid1b |
GCG |
GCGACG |
17: 5,045,869 (GRCm39) |
|
probably benign |
Het |
| Arid1b |
CGG |
CGGAGG |
17: 5,045,870 (GRCm39) |
|
probably benign |
Het |
| Begain |
G |
GCCGCCC |
12: 108,999,363 (GRCm39) |
|
probably null |
Het |
| Cacna1e |
A |
G |
1: 154,317,882 (GRCm39) |
M1500T |
probably damaging |
Het |
| Casp16 |
C |
A |
17: 23,774,201 (GRCm39) |
|
probably benign |
Het |
| Ccdc174 |
T |
C |
6: 91,876,347 (GRCm39) |
S395P |
possibly damaging |
Het |
| Ccdc7a |
T |
G |
8: 129,691,434 (GRCm39) |
Q396H |
probably damaging |
Het |
| Ccdc85c |
CC |
CCGGC |
12: 108,240,887 (GRCm39) |
|
probably benign |
Het |
| Cemip |
T |
C |
7: 83,610,843 (GRCm39) |
T704A |
probably damaging |
Het |
| Cfap68 |
C |
T |
9: 50,677,067 (GRCm39) |
R8H |
probably benign |
Het |
| Col7a1 |
C |
T |
9: 108,793,547 (GRCm39) |
P1370S |
unknown |
Het |
| Cts8 |
T |
C |
13: 61,397,102 (GRCm39) |
I273V |
probably benign |
Het |
| Cyp2c50 |
T |
A |
19: 40,078,268 (GRCm39) |
I42N |
probably damaging |
Het |
| Dbt |
T |
G |
3: 116,341,717 (GRCm39) |
Y439* |
probably null |
Het |
| Dennd1b |
T |
A |
1: 138,981,135 (GRCm39) |
D116E |
probably damaging |
Het |
| Dkk2 |
T |
A |
3: 131,883,863 (GRCm39) |
H254Q |
probably damaging |
Het |
| Dpy30 |
C |
A |
17: 74,622,902 (GRCm39) |
V27F |
possibly damaging |
Het |
| Efhd2 |
GCCGCC |
GCCGCCCCCGCC |
4: 141,602,069 (GRCm39) |
|
probably benign |
Het |
| Eif4g3 |
A |
T |
4: 137,903,235 (GRCm39) |
E1020V |
probably damaging |
Het |
| Elmo1 |
T |
A |
13: 20,458,706 (GRCm39) |
S156T |
probably benign |
Het |
| Fancd2os |
T |
C |
6: 113,574,881 (GRCm39) |
T42A |
probably damaging |
Het |
| Fbrsl1 |
TGTGC |
TGTGCGGGTGTGGGTGC |
5: 110,525,984 (GRCm39) |
|
probably benign |
Het |
| Fsip2 |
T |
C |
2: 82,808,184 (GRCm39) |
V1501A |
probably benign |
Het |
| Gabrb2 |
A |
G |
11: 42,517,705 (GRCm39) |
Y509C |
probably damaging |
Het |
| Gm8369 |
GTGT |
GTGTTTGT |
19: 11,489,118 (GRCm39) |
|
probably null |
Het |
| Gpr139 |
T |
C |
7: 118,744,090 (GRCm39) |
D165G |
probably benign |
Het |
| Grik2 |
T |
C |
10: 49,120,480 (GRCm39) |
E603G |
probably damaging |
Het |
| H13 |
G |
A |
2: 152,511,589 (GRCm39) |
E30K |
probably damaging |
Het |
| Ifitm10 |
T |
A |
7: 141,882,330 (GRCm39) |
M147L |
unknown |
Het |
| Itpkb |
C |
T |
1: 180,160,887 (GRCm39) |
R338W |
probably damaging |
Het |
| Kif1b |
T |
A |
4: 149,336,195 (GRCm39) |
|
probably null |
Het |
| Krtap28-10 |
ACCACAGCCACAGCCACCACAGCCACAGCCACCACAGC |
ACCACAGCCACAGCCACCACAGCCACAGCCACCACAGCCACAGCCACCACAGC |
1: 83,019,974 (GRCm39) |
|
probably benign |
Het |
| Krtap28-10 |
AGCCACCACAGC |
AGCCACCACAGCCACCGCCACCACAGC |
1: 83,020,000 (GRCm39) |
|
probably benign |
Het |
| Krtap28-10 |
CAGCCA |
CAGCCATAGCCA |
1: 83,019,849 (GRCm39) |
|
probably benign |
Het |
| Krtap28-10 |
AGCCAC |
AGCCACCGCCAC |
1: 83,019,856 (GRCm39) |
|
probably benign |
Het |
| Las1l |
AGTGG |
AGTGGTGG |
X: 94,984,422 (GRCm39) |
|
probably benign |
Het |
| Mical2 |
T |
C |
7: 111,922,833 (GRCm39) |
Y613H |
probably damaging |
Het |
| Mlf2 |
C |
A |
6: 124,911,259 (GRCm39) |
H91Q |
probably benign |
Het |
| Nat9 |
A |
T |
11: 115,074,212 (GRCm39) |
I152N |
probably damaging |
Het |
| Or10d4c |
T |
C |
9: 39,558,559 (GRCm39) |
M179T |
probably benign |
Het |
| Or4a75 |
A |
T |
2: 89,447,711 (GRCm39) |
I275N |
possibly damaging |
Het |
| Pdik1l |
CACCAC |
CACCACAACCAC |
4: 134,006,822 (GRCm39) |
|
probably benign |
Het |
| Pkhd1l1 |
TTTT |
TTTTTTTTTTGTTT |
15: 44,421,901 (GRCm39) |
|
probably benign |
Het |
| Plcg2 |
T |
A |
8: 118,300,263 (GRCm39) |
|
probably null |
Het |
| Polr1has |
CACCACCACCACCACCAC |
CACCACCACCACCACCACCACAACCACCACCACCACCAC |
17: 37,275,946 (GRCm39) |
|
probably benign |
Het |
| Prdm16 |
T |
A |
4: 154,426,452 (GRCm39) |
R444S |
probably damaging |
Het |
| Rgs6 |
T |
C |
12: 83,110,223 (GRCm39) |
F163L |
probably damaging |
Het |
| Rnaseh2a |
A |
T |
8: 85,686,687 (GRCm39) |
L154* |
probably null |
Het |
| Rpp38 |
A |
G |
2: 3,330,072 (GRCm39) |
S277P |
unknown |
Het |
| Setd1a |
GGTAGTGGT |
GGTAGTGGTTGTAGTGGT |
7: 127,384,486 (GRCm39) |
|
probably benign |
Het |
| Shisa6 |
CGACAGCAGCAGAG |
CG |
11: 66,416,749 (GRCm39) |
|
probably benign |
Het |
| Slc27a2 |
T |
A |
2: 126,395,175 (GRCm39) |
L34Q |
possibly damaging |
Het |
| Slc7a6 |
G |
A |
8: 106,922,030 (GRCm39) |
V386I |
probably benign |
Het |
| Spry1 |
C |
T |
3: 37,697,264 (GRCm39) |
T169I |
possibly damaging |
Het |
| Sry |
TGCTGCTGCTG |
TGCTGCTGCTGCTG |
Y: 2,662,826 (GRCm39) |
|
probably benign |
Het |
| Stk24 |
A |
T |
14: 121,532,172 (GRCm39) |
I275N |
probably benign |
Het |
| Strn |
TC |
TCCGTGCTCCCTTACCCCAGTCCGTGCTCCCTTACCCCAGGC |
17: 78,984,716 (GRCm39) |
|
probably null |
Het |
| Tcp11l2 |
C |
A |
10: 84,449,388 (GRCm39) |
P451Q |
probably damaging |
Het |
| Tfeb |
AGC |
AGCTGC |
17: 48,097,027 (GRCm39) |
|
probably benign |
Het |
| Trappc9 |
TGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCT |
TGCTGCTGCTGCTGCGGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCT |
15: 72,673,138 (GRCm39) |
|
probably benign |
Het |
| V1ra8 |
A |
G |
6: 90,180,591 (GRCm39) |
T265A |
probably benign |
Het |
| Zfp106 |
CTCCTGGCAGT |
CT |
2: 120,355,026 (GRCm39) |
|
probably benign |
Het |
| Zfp612 |
C |
A |
8: 110,816,193 (GRCm39) |
H467N |
probably damaging |
Het |
| Zfp777 |
A |
T |
6: 48,018,982 (GRCm39) |
Y317* |
probably null |
Het |
|
| Other mutations in Phldb2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00321:Phldb2
|
APN |
16 |
45,592,617 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00485:Phldb2
|
APN |
16 |
45,577,551 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
IGL00544:Phldb2
|
APN |
16 |
45,645,674 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00547:Phldb2
|
APN |
16 |
45,645,898 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00835:Phldb2
|
APN |
16 |
45,571,819 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00987:Phldb2
|
APN |
16 |
45,583,465 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
IGL01102:Phldb2
|
APN |
16 |
45,645,423 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01530:Phldb2
|
APN |
16 |
45,623,092 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01549:Phldb2
|
APN |
16 |
45,594,681 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01712:Phldb2
|
APN |
16 |
45,571,792 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01755:Phldb2
|
APN |
16 |
45,645,945 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01823:Phldb2
|
APN |
16 |
45,645,507 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02353:Phldb2
|
APN |
16 |
45,569,142 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02360:Phldb2
|
APN |
16 |
45,569,142 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02716:Phldb2
|
APN |
16 |
45,621,953 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0139:Phldb2
|
UTSW |
16 |
45,591,029 (GRCm39) |
splice site |
probably benign |
|
|
R0312:Phldb2
|
UTSW |
16 |
45,609,410 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0379:Phldb2
|
UTSW |
16 |
45,601,814 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0535:Phldb2
|
UTSW |
16 |
45,577,490 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1387:Phldb2
|
UTSW |
16 |
45,646,357 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R1444:Phldb2
|
UTSW |
16 |
45,577,616 (GRCm39) |
splice site |
probably benign |
|
|
R1487:Phldb2
|
UTSW |
16 |
45,609,387 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1501:Phldb2
|
UTSW |
16 |
45,598,146 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1605:Phldb2
|
UTSW |
16 |
45,591,142 (GRCm39) |
splice site |
probably benign |
|
|
R1716:Phldb2
|
UTSW |
16 |
45,595,413 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1732:Phldb2
|
UTSW |
16 |
45,577,529 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1779:Phldb2
|
UTSW |
16 |
45,621,988 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1824:Phldb2
|
UTSW |
16 |
45,646,374 (GRCm39) |
missense |
probably benign |
0.14 |
|
R2001:Phldb2
|
UTSW |
16 |
45,594,558 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R2066:Phldb2
|
UTSW |
16 |
45,591,121 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2122:Phldb2
|
UTSW |
16 |
45,583,304 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2448:Phldb2
|
UTSW |
16 |
45,645,726 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2932:Phldb2
|
UTSW |
16 |
45,569,148 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R3076:Phldb2
|
UTSW |
16 |
45,645,373 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3078:Phldb2
|
UTSW |
16 |
45,645,373 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3779:Phldb2
|
UTSW |
16 |
45,569,118 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3914:Phldb2
|
UTSW |
16 |
45,577,526 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4536:Phldb2
|
UTSW |
16 |
45,591,044 (GRCm39) |
missense |
probably benign |
0.04 |
|
R4568:Phldb2
|
UTSW |
16 |
45,598,081 (GRCm39) |
nonsense |
probably null |
|
|
R4798:Phldb2
|
UTSW |
16 |
45,646,237 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4853:Phldb2
|
UTSW |
16 |
45,623,079 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4906:Phldb2
|
UTSW |
16 |
45,571,758 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4984:Phldb2
|
UTSW |
16 |
45,645,996 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5078:Phldb2
|
UTSW |
16 |
45,598,105 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R5137:Phldb2
|
UTSW |
16 |
45,628,621 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R5237:Phldb2
|
UTSW |
16 |
45,568,249 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5410:Phldb2
|
UTSW |
16 |
45,645,975 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R5825:Phldb2
|
UTSW |
16 |
45,583,460 (GRCm39) |
missense |
probably benign |
0.11 |
|
R5874:Phldb2
|
UTSW |
16 |
45,621,988 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5907:Phldb2
|
UTSW |
16 |
45,645,551 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6332:Phldb2
|
UTSW |
16 |
45,594,609 (GRCm39) |
missense |
probably benign |
|
|
R6354:Phldb2
|
UTSW |
16 |
45,645,477 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6355:Phldb2
|
UTSW |
16 |
45,645,701 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6383:Phldb2
|
UTSW |
16 |
45,569,113 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6463:Phldb2
|
UTSW |
16 |
45,595,356 (GRCm39) |
missense |
probably benign |
0.37 |
|
R6513:Phldb2
|
UTSW |
16 |
45,568,240 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R6593:Phldb2
|
UTSW |
16 |
45,645,790 (GRCm39) |
nonsense |
probably null |
|
|
R6756:Phldb2
|
UTSW |
16 |
45,628,683 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6810:Phldb2
|
UTSW |
16 |
45,569,088 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6897:Phldb2
|
UTSW |
16 |
45,598,138 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7010:Phldb2
|
UTSW |
16 |
45,571,868 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7142:Phldb2
|
UTSW |
16 |
45,577,539 (GRCm39) |
nonsense |
probably null |
|
|
R7149:Phldb2
|
UTSW |
16 |
45,571,895 (GRCm39) |
nonsense |
probably null |
|
|
R7249:Phldb2
|
UTSW |
16 |
45,621,977 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7300:Phldb2
|
UTSW |
16 |
45,645,925 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7328:Phldb2
|
UTSW |
16 |
45,578,572 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7515:Phldb2
|
UTSW |
16 |
45,594,603 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7840:Phldb2
|
UTSW |
16 |
45,571,727 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7988:Phldb2
|
UTSW |
16 |
45,645,934 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8159:Phldb2
|
UTSW |
16 |
45,680,747 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R8353:Phldb2
|
UTSW |
16 |
45,645,385 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8453:Phldb2
|
UTSW |
16 |
45,645,385 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8969:Phldb2
|
UTSW |
16 |
45,592,496 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9058:Phldb2
|
UTSW |
16 |
45,592,604 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R9106:Phldb2
|
UTSW |
16 |
45,680,757 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9278:Phldb2
|
UTSW |
16 |
45,646,308 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9324:Phldb2
|
UTSW |
16 |
45,595,437 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9563:Phldb2
|
UTSW |
16 |
45,645,247 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R9626:Phldb2
|
UTSW |
16 |
45,592,547 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R9712:Phldb2
|
UTSW |
16 |
45,595,340 (GRCm39) |
missense |
probably benign |
0.27 |
|
R9718:Phldb2
|
UTSW |
16 |
45,601,756 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
Z1176:Phldb2
|
UTSW |
16 |
45,773,871 (GRCm39) |
unclassified |
probably benign |
|
|
Z1176:Phldb2
|
UTSW |
16 |
45,646,190 (GRCm39) |
missense |
probably benign |
0.04 |
|
Z1176:Phldb2
|
UTSW |
16 |
45,646,189 (GRCm39) |
missense |
probably benign |
0.43 |
|
Z1190:Phldb2
|
UTSW |
16 |
45,645,697 (GRCm39) |
missense |
probably damaging |
0.96 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGGGTCCCCAAGATTCCTAG -3'
(R):5'- CCATAGATTTGTGAGATTCTGAGC -3'
Sequencing Primer
(F):5'- AGATTCCTAGCCCCCGC -3'
(R):5'- GTGAGATTCTGAGCTTGATAAATGAG -3'
|
| Posted On |
2019-12-04 |
Incidental Mutation