Incidental Mutation 'RF009:Atrn'
| ID |
603031 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Atrn
|
| Ensembl Gene |
ENSMUSG00000027312 |
| Gene Name |
attractin |
| Synonyms |
Mgca |
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
RF009 (G1)
|
| Quality Score |
175.009 |
|
Status
|
Validated
|
| Chromosome |
2 |
| Chromosomal Location |
130906495-131030333 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to A
at 130906922 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Lysine
at position 121
(T121K)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000028781
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000028781]
[ENSMUST00000146975]
|
| AlphaFold |
Q9WU60 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000028781
AA Change: T121K
PolyPhen 2
Score 0.116 (Sensitivity: 0.93; Specificity: 0.86)
|
| SMART Domains |
Protein: ENSMUSP00000028781
Gene: ENSMUSG00000027312
AA Change: T121K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
9 |
N/A |
INTRINSIC |
|
low complexity region
|
51 |
97 |
N/A |
INTRINSIC |
|
EGF
|
99 |
129 |
9.85e-5 |
SMART |
|
CUB
|
131 |
247 |
7.85e-18 |
SMART |
|
EGF
|
248 |
282 |
1.47e1 |
SMART |
|
Pfam:Kelch_1
|
339 |
382 |
1.1e-7 |
PFAM |
|
Pfam:Kelch_5
|
389 |
434 |
2.5e-7 |
PFAM |
|
Pfam:Kelch_6
|
390 |
439 |
3.3e-8 |
PFAM |
|
Pfam:Kelch_1
|
553 |
606 |
8.4e-8 |
PFAM |
|
PSI
|
646 |
693 |
7.41e-7 |
SMART |
|
PSI
|
702 |
747 |
8.64e-8 |
SMART |
|
PSI
|
754 |
799 |
2.11e-2 |
SMART |
|
CLECT
|
787 |
918 |
6.14e-20 |
SMART |
|
PSI
|
931 |
982 |
1.11e-5 |
SMART |
|
PSI
|
985 |
1060 |
1.2e-6 |
SMART |
|
EGF_Lam
|
1062 |
1105 |
1.97e-4 |
SMART |
|
EGF_like
|
1108 |
1154 |
3.9e0 |
SMART |
|
transmembrane domain
|
1278 |
1300 |
N/A |
INTRINSIC |
|
low complexity region
|
1310 |
1322 |
N/A |
INTRINSIC |
|
low complexity region
|
1373 |
1385 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000146975
|
| Coding Region Coverage |
- 1x: 99.8%
- 3x: 99.7%
- 10x: 99.3%
- 20x: 98.5%
|
| Validation Efficiency |
96% (53/55) |
| MGI Phenotype |
FUNCTION: This gene encodes a widely expressed transmembrane glycoprotein that plays important roles in diverse physiological processes such as regulation of hair pigmentation, monocyte-T cell interaction and control of energy homeostasis. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional protein. Certain mutations in this gene are responsible for the mahogany mouse phenotype of dark brown or black coat on a normally agouti background. Mice with loss-of-function mutations in this gene exhibit black coat color, tremor, adiposity, higher basal metabolic rate, juvenile-onset hypomyelination and age-dependent spongiform neurodegeneration of the central nervous system. [provided by RefSeq, Jul 2016]
PHENOTYPE: Some mutant homozygotes exhibit decreases in phaeomelanin synthesis, body weight, and adiposity; increases in locomotion, and abnormal myelination and vacuolation of the central nervous system resulting in tremors. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 85 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 6030445D17Rik |
ACACACACCCGC |
AC |
4: 136,462,350 (GRCm38) |
|
probably null |
Het |
| AI182371 |
A |
G |
2: 35,089,197 (GRCm38) |
V153A |
possibly damaging |
Het |
| AI837181 |
CGG |
CGGTGG |
19: 5,425,234 (GRCm38) |
|
probably benign |
Het |
| Ankhd1 |
GCGGCG |
GCGGCGTCGGCG |
18: 36,560,922 (GRCm38) |
|
probably benign |
Het |
| Apoc2 |
C |
T |
7: 19,671,842 (GRCm38) |
M71I |
probably benign |
Het |
| Arhgap17 |
CTGTTGTTG |
CTGTTG |
7: 123,286,862 (GRCm38) |
|
probably benign |
Het |
| Btnl12 |
T |
C |
16: 37,854,479 (GRCm38) |
D207G |
probably benign |
Het |
| Ccdc170 |
C |
CCAG |
10: 4,561,030 (GRCm38) |
|
probably benign |
Het |
| Cckbr |
GCA |
G |
7: 105,434,686 (GRCm38) |
|
probably null |
Het |
| Cdk13 |
T |
C |
13: 17,803,744 (GRCm38) |
D303G |
unknown |
Het |
| Cfap65 |
C |
A |
1: 74,905,647 (GRCm38) |
R1477L |
probably damaging |
Het |
| Chd2 |
A |
G |
7: 73,519,662 (GRCm38) |
S37P |
possibly damaging |
Het |
| Chga |
AGC |
AGCCGC |
12: 102,561,420 (GRCm38) |
|
probably benign |
Het |
| Csf2rb2 |
T |
C |
15: 78,291,927 (GRCm38) |
I259V |
probably benign |
Het |
| Csnk1d |
A |
T |
11: 120,971,627 (GRCm38) |
N275K |
possibly damaging |
Het |
| Dmxl1 |
A |
C |
18: 49,893,394 (GRCm38) |
R1856S |
probably damaging |
Het |
| Dnah5 |
T |
C |
15: 28,204,019 (GRCm38) |
V14A |
probably benign |
Het |
| Edc4 |
G |
A |
8: 105,889,180 (GRCm38) |
S729N |
probably benign |
Het |
| Emilin3 |
T |
C |
2: 160,909,092 (GRCm38) |
S246G |
probably benign |
Het |
| Epc2 |
T |
G |
2: 49,532,237 (GRCm38) |
|
probably null |
Het |
| Exoc6 |
T |
A |
19: 37,571,620 (GRCm38) |
F101I |
probably benign |
Het |
| Fam171b |
GCAGCA |
GCAGCACCAGCA |
2: 83,812,880 (GRCm38) |
|
probably benign |
Het |
| Fam81b |
CTGTT |
CTGTTGTT |
13: 76,271,316 (GRCm38) |
|
probably benign |
Het |
| Flywch1 |
CTCACCCACTCCTGGTGT |
CTCACCCACTCCTGGTGTGGGGAGGCTACGTAGTCACCCACTCCTGGTGT |
17: 23,762,161 (GRCm38) |
|
probably null |
Het |
| Gab3 |
CTT |
CTTATT |
X: 75,000,024 (GRCm38) |
|
probably null |
Het |
| Gab3 |
TTC |
TTCCTC |
X: 74,999,992 (GRCm38) |
|
probably benign |
Het |
| Gabpa |
C |
A |
16: 84,844,336 (GRCm38) |
Q93K |
probably benign |
Het |
| Gabre |
GGGCTCAGGCTCAGGCTCAGGCTCAGGCTCAGGCTCAGGCTCAGGCTCAGGCTCAGGCTCTGGCTCAGGCTC |
GGGCTCAGGCTCAGGCTCAGGCTCAGGCTCAGGCTCAGGCTCAGGCTCAGGCTCTGGCTCAGGCTC |
X: 72,270,712 (GRCm38) |
|
probably benign |
Het |
| Gabre |
GGCTCA |
GGCTCAAGCTCA |
X: 72,270,713 (GRCm38) |
|
probably benign |
Het |
| H2-T3 |
TCCCGAAGAAC |
TC |
17: 36,189,402 (GRCm38) |
|
probably benign |
Het |
| Htr5a |
A |
G |
5: 27,842,861 (GRCm38) |
D138G |
probably damaging |
Het |
| Ifi207 |
G |
A |
1: 173,728,992 (GRCm38) |
P727S |
probably benign |
Het |
| Ifna13 |
T |
A |
4: 88,643,908 (GRCm38) |
S160C |
probably damaging |
Het |
| Kcnh8 |
G |
A |
17: 52,978,239 (GRCm38) |
R1079H |
probably benign |
Het |
| Klri2 |
GGAG |
GG |
6: 129,733,774 (GRCm38) |
|
probably null |
Het |
| Lce1m |
GTTGCTGCCACTG |
GTTGCTGCCACTGTTGCTGCCACTG |
3: 93,018,131 (GRCm38) |
|
probably benign |
Het |
| Lrch1 |
TTGGTGGTGCTGGTGG |
TTGGTGG |
14: 74,947,574 (GRCm38) |
|
probably benign |
Het |
| Lrch4 |
A |
G |
5: 137,637,543 (GRCm38) |
|
probably null |
Het |
| Lrrc2 |
TTGATTCGGTTCACC |
T |
9: 110,981,676 (GRCm38) |
|
probably null |
Het |
| Map1a |
GCTCCAGC |
GCTCCAGCCCCAGCTCCAGCTCCAGCTCCACCTCCAGC |
2: 121,306,301 (GRCm38) |
|
probably benign |
Het |
| Mettl25 |
T |
C |
10: 105,833,239 (GRCm38) |
|
probably benign |
Het |
| Mex3b |
A |
G |
7: 82,867,760 (GRCm38) |
D37G |
probably damaging |
Het |
| Mon1a |
T |
A |
9: 107,901,234 (GRCm38) |
V219E |
probably damaging |
Het |
| Myh3 |
GATTA |
GATTAATTA |
11: 67,086,355 (GRCm38) |
|
probably null |
Het |
| Myh3 |
ATTAC |
ATTACTTAC |
11: 67,086,356 (GRCm38) |
|
probably null |
Het |
| Myh3 |
TTACG |
TTACGTACG |
11: 67,086,357 (GRCm38) |
|
probably null |
Het |
| Myo5b |
T |
A |
18: 74,643,999 (GRCm38) |
C377S |
probably damaging |
Het |
| Nefh |
ACTTGGCCTCAGCTGGGG |
ACTTGGCCTCAGCTGGGGCCTTGGCCTCAGCTGGGG |
11: 4,940,997 (GRCm38) |
|
probably benign |
Het |
| Nos1ap |
T |
C |
1: 170,318,581 (GRCm38) |
D468G |
probably damaging |
Het |
| Ntn5 |
T |
C |
7: 45,693,260 (GRCm38) |
|
probably null |
Het |
| Oog2 |
T |
C |
4: 144,195,285 (GRCm38) |
V255A |
probably benign |
Het |
| Or5ac15 |
T |
A |
16: 59,119,911 (GRCm38) |
H53L |
probably damaging |
Het |
| Or8b37 |
A |
T |
9: 38,047,747 (GRCm38) |
H175L |
probably damaging |
Het |
| Pdgfd |
C |
A |
9: 6,288,624 (GRCm38) |
L93M |
probably damaging |
Het |
| Pgls |
G |
T |
8: 71,592,463 (GRCm38) |
V83L |
probably damaging |
Het |
| Pigw |
C |
A |
11: 84,877,161 (GRCm38) |
Q447H |
probably damaging |
Het |
| Pnma8a |
TCATGATGCACCTGCTTCAACATC |
TCATGATGCACCTGCTTCAACATCGCATGATGCACCTGCTTCAACATC |
7: 16,961,427 (GRCm38) |
|
probably benign |
Het |
| Poc1a |
C |
A |
9: 106,295,218 (GRCm38) |
L253M |
possibly damaging |
Het |
| Ppl |
T |
A |
16: 5,097,931 (GRCm38) |
E589D |
probably benign |
Het |
| Prkar1b |
A |
G |
5: 139,108,621 (GRCm38) |
S71P |
probably benign |
Het |
| Prx |
T |
C |
7: 27,518,960 (GRCm38) |
F1101S |
probably damaging |
Het |
| Rffl |
A |
G |
11: 82,845,772 (GRCm38) |
V26A |
probably benign |
Het |
| Scube3 |
T |
A |
17: 28,168,397 (GRCm38) |
L923Q |
probably damaging |
Het |
| Setd2 |
C |
T |
9: 110,550,711 (GRCm38) |
P1198L |
probably damaging |
Het |
| Shank2 |
C |
A |
7: 144,411,571 (GRCm38) |
A972E |
possibly damaging |
Het |
| Slc10a6 |
A |
G |
5: 103,608,992 (GRCm38) |
L302P |
probably damaging |
Het |
| Slc29a3 |
C |
T |
10: 60,750,561 (GRCm38) |
G42D |
probably benign |
Het |
| Spart |
T |
C |
3: 55,127,606 (GRCm38) |
V471A |
probably benign |
Het |
| Srebf1 |
T |
C |
11: 60,204,116 (GRCm38) |
T486A |
probably benign |
Het |
| Sspo |
T |
A |
6: 48,459,985 (GRCm38) |
Y1284* |
probably null |
Het |
| Supt20 |
AGCAGC |
AGCAGCCGCAGC |
3: 54,727,662 (GRCm38) |
|
probably benign |
Het |
| Tcof1 |
GCA |
GCACCA |
18: 60,835,743 (GRCm38) |
|
probably benign |
Het |
| Tff1 |
CTTCCTG |
C |
17: 31,164,927 (GRCm38) |
|
probably benign |
Het |
| Tmprss13 |
ATCTCCAGCAAGGGCACCTCCTCAGGCCTCTCCAGCAAGGACACCTCCTCAGGCCTCTCCAACAAGGACACCTCCTCAGGCCTCTCCAGCAAGGGCACCTCCTC |
ATCTCCAGCAAGGGCACCTCCTCAGGGCTCTCCAGCAAGGGCACCTCCTCAGGCCTCTCCAGCAAGGACACCTCCTCAGGCCTCTCCAACAAGGACACCTCCTCAGGCCTCTCCAGCAAGGGCACCTCCTC |
9: 45,328,464 (GRCm38) |
|
probably benign |
Het |
| Tnfrsf25 |
T |
C |
4: 152,119,624 (GRCm38) |
W341R |
probably damaging |
Het |
| Trappc9 |
GCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCT |
GCTGCTGCTGCTGCTTCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCT |
15: 72,801,287 (GRCm38) |
|
probably benign |
Het |
| Trav8d-1 |
T |
A |
14: 52,778,750 (GRCm38) |
L31Q |
probably damaging |
Het |
| Ttc23 |
A |
T |
7: 67,726,029 (GRCm38) |
I452F |
possibly damaging |
Het |
| Uimc1 |
T |
C |
13: 55,050,785 (GRCm38) |
E526G |
possibly damaging |
Het |
| Ulbp1 |
T |
A |
10: 7,447,405 (GRCm38) |
K233N |
unknown |
Het |
| Usp17ld |
A |
T |
7: 103,250,288 (GRCm38) |
V479E |
probably damaging |
Het |
| Utrn |
T |
TGTTACCC |
10: 12,633,945 (GRCm38) |
|
probably null |
Het |
| Vmn1r9 |
C |
T |
6: 57,071,480 (GRCm38) |
S180L |
probably benign |
Het |
| Wdr97 |
GAGGAGGA |
G |
15: 76,363,167 (GRCm38) |
|
probably null |
Het |
| Zfp598 |
CACC |
CACCCCTACC |
17: 24,680,787 (GRCm38) |
|
probably benign |
Het |
|
| Other mutations in Atrn |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00337:Atrn
|
APN |
2 |
130,958,079 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL00571:Atrn
|
APN |
2 |
130,995,048 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01092:Atrn
|
APN |
2 |
130,947,636 (GRCm38) |
nonsense |
probably null |
|
|
IGL01572:Atrn
|
APN |
2 |
131,002,795 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01924:Atrn
|
APN |
2 |
130,935,565 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02116:Atrn
|
APN |
2 |
130,958,089 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02372:Atrn
|
APN |
2 |
131,002,754 (GRCm38) |
splice site |
probably benign |
|
|
IGL02390:Atrn
|
APN |
2 |
131,020,977 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
IGL02548:Atrn
|
APN |
2 |
130,972,282 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02749:Atrn
|
APN |
2 |
130,947,734 (GRCm38) |
splice site |
probably benign |
|
|
IGL02749:Atrn
|
APN |
2 |
130,970,144 (GRCm38) |
nonsense |
probably null |
|
|
BB010:Atrn
|
UTSW |
2 |
130,995,066 (GRCm38) |
missense |
probably damaging |
1.00 |
|
BB020:Atrn
|
UTSW |
2 |
130,995,066 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0026:Atrn
|
UTSW |
2 |
130,957,920 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0403:Atrn
|
UTSW |
2 |
130,906,859 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0479:Atrn
|
UTSW |
2 |
130,999,165 (GRCm38) |
nonsense |
probably null |
|
|
R0544:Atrn
|
UTSW |
2 |
130,986,826 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0570:Atrn
|
UTSW |
2 |
130,980,134 (GRCm38) |
missense |
probably benign |
0.01 |
|
R0606:Atrn
|
UTSW |
2 |
130,906,856 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R0617:Atrn
|
UTSW |
2 |
130,995,085 (GRCm38) |
critical splice donor site |
probably null |
|
|
R0658:Atrn
|
UTSW |
2 |
130,970,227 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1108:Atrn
|
UTSW |
2 |
130,957,914 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1112:Atrn
|
UTSW |
2 |
130,999,161 (GRCm38) |
missense |
probably benign |
0.04 |
|
R1219:Atrn
|
UTSW |
2 |
131,021,007 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R1422:Atrn
|
UTSW |
2 |
130,957,914 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1524:Atrn
|
UTSW |
2 |
130,957,080 (GRCm38) |
missense |
probably benign |
0.15 |
|
R1653:Atrn
|
UTSW |
2 |
130,935,624 (GRCm38) |
missense |
probably benign |
|
|
R1795:Atrn
|
UTSW |
2 |
130,972,288 (GRCm38) |
missense |
probably benign |
|
|
R1807:Atrn
|
UTSW |
2 |
130,982,772 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R1920:Atrn
|
UTSW |
2 |
130,995,051 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1921:Atrn
|
UTSW |
2 |
130,995,051 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1935:Atrn
|
UTSW |
2 |
130,958,035 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1982:Atrn
|
UTSW |
2 |
130,970,222 (GRCm38) |
missense |
probably benign |
|
|
R2000:Atrn
|
UTSW |
2 |
130,935,588 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2143:Atrn
|
UTSW |
2 |
130,957,996 (GRCm38) |
missense |
probably benign |
0.03 |
|
R2336:Atrn
|
UTSW |
2 |
130,957,954 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2679:Atrn
|
UTSW |
2 |
130,961,675 (GRCm38) |
critical splice donor site |
probably null |
|
|
R3426:Atrn
|
UTSW |
2 |
131,020,956 (GRCm38) |
missense |
probably benign |
0.06 |
|
R3909:Atrn
|
UTSW |
2 |
130,994,207 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4077:Atrn
|
UTSW |
2 |
130,964,930 (GRCm38) |
critical splice donor site |
probably null |
|
|
R4162:Atrn
|
UTSW |
2 |
130,994,228 (GRCm38) |
splice site |
probably benign |
|
|
R4195:Atrn
|
UTSW |
2 |
130,933,412 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4364:Atrn
|
UTSW |
2 |
130,970,208 (GRCm38) |
missense |
probably benign |
0.39 |
|
R4465:Atrn
|
UTSW |
2 |
130,960,468 (GRCm38) |
missense |
probably benign |
0.08 |
|
R4510:Atrn
|
UTSW |
2 |
130,935,577 (GRCm38) |
nonsense |
probably null |
|
|
R4511:Atrn
|
UTSW |
2 |
130,935,577 (GRCm38) |
nonsense |
probably null |
|
|
R4527:Atrn
|
UTSW |
2 |
130,973,504 (GRCm38) |
missense |
probably benign |
0.10 |
|
R4586:Atrn
|
UTSW |
2 |
130,982,042 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4592:Atrn
|
UTSW |
2 |
130,999,130 (GRCm38) |
intron |
probably benign |
|
|
R4658:Atrn
|
UTSW |
2 |
130,933,429 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4735:Atrn
|
UTSW |
2 |
131,020,990 (GRCm38) |
missense |
probably benign |
0.06 |
|
R4960:Atrn
|
UTSW |
2 |
130,995,047 (GRCm38) |
nonsense |
probably null |
|
|
R4999:Atrn
|
UTSW |
2 |
130,975,954 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5066:Atrn
|
UTSW |
2 |
130,994,193 (GRCm38) |
missense |
possibly damaging |
0.60 |
|
R5080:Atrn
|
UTSW |
2 |
130,970,124 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R5141:Atrn
|
UTSW |
2 |
130,999,130 (GRCm38) |
intron |
probably benign |
|
|
R5256:Atrn
|
UTSW |
2 |
130,946,019 (GRCm38) |
missense |
probably benign |
0.39 |
|
R5494:Atrn
|
UTSW |
2 |
131,023,075 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5678:Atrn
|
UTSW |
2 |
130,970,016 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R5752:Atrn
|
UTSW |
2 |
130,906,544 (GRCm38) |
unclassified |
probably benign |
|
|
R5931:Atrn
|
UTSW |
2 |
130,933,436 (GRCm38) |
missense |
possibly damaging |
0.56 |
|
R6023:Atrn
|
UTSW |
2 |
131,020,980 (GRCm38) |
missense |
probably benign |
0.25 |
|
R6176:Atrn
|
UTSW |
2 |
130,946,091 (GRCm38) |
missense |
probably benign |
0.31 |
|
R6377:Atrn
|
UTSW |
2 |
130,979,969 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6433:Atrn
|
UTSW |
2 |
131,023,027 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7226:Atrn
|
UTSW |
2 |
130,986,744 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R7402:Atrn
|
UTSW |
2 |
130,947,600 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7541:Atrn
|
UTSW |
2 |
130,961,571 (GRCm38) |
missense |
possibly damaging |
0.46 |
|
R7587:Atrn
|
UTSW |
2 |
130,980,114 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7872:Atrn
|
UTSW |
2 |
130,970,227 (GRCm38) |
critical splice donor site |
probably null |
|
|
R7910:Atrn
|
UTSW |
2 |
130,964,887 (GRCm38) |
missense |
probably benign |
0.04 |
|
R7913:Atrn
|
UTSW |
2 |
130,970,211 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7933:Atrn
|
UTSW |
2 |
130,995,066 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8044:Atrn
|
UTSW |
2 |
130,935,529 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8079:Atrn
|
UTSW |
2 |
131,013,641 (GRCm38) |
missense |
probably null |
1.00 |
|
R8093:Atrn
|
UTSW |
2 |
130,975,988 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8203:Atrn
|
UTSW |
2 |
130,960,549 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8234:Atrn
|
UTSW |
2 |
131,023,000 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
R8462:Atrn
|
UTSW |
2 |
130,935,584 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8816:Atrn
|
UTSW |
2 |
131,004,574 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8816:Atrn
|
UTSW |
2 |
130,906,878 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8831:Atrn
|
UTSW |
2 |
130,906,601 (GRCm38) |
missense |
probably benign |
0.22 |
|
R8937:Atrn
|
UTSW |
2 |
130,999,237 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9161:Atrn
|
UTSW |
2 |
130,935,550 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9722:Atrn
|
UTSW |
2 |
130,961,616 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9786:Atrn
|
UTSW |
2 |
130,944,889 (GRCm38) |
missense |
probably damaging |
1.00 |
|
X0024:Atrn
|
UTSW |
2 |
130,958,139 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1088:Atrn
|
UTSW |
2 |
130,973,399 (GRCm38) |
missense |
probably benign |
|
|
Z1176:Atrn
|
UTSW |
2 |
130,946,193 (GRCm38) |
missense |
probably benign |
0.27 |
|
Z1177:Atrn
|
UTSW |
2 |
130,946,042 (GRCm38) |
missense |
probably damaging |
0.99 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTGGATATGGACCCGCCG -3'
(R):5'- CTCCAGGAGGCAAGCCATC -3'
Sequencing Primer
(F):5'- TCAGCCCCAGGAAGATGGTG -3'
(R):5'- TCATCAAACACAGTGGGGC -3'
|
| Posted On |
2019-12-04 |
Incidental Mutation