Incidental Mutation 'RF013:Myo10'
| ID |
603366 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Myo10
|
| Ensembl Gene |
ENSMUSG00000022272 |
| Gene Name |
myosin X |
| Synonyms |
myosin-X, D15Ertd600e |
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
RF013 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
15 |
| Chromosomal Location |
25622636-25813759 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 25799565 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Methionine to Lysine
at position 1376
(M1376K)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000106087
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000022882]
[ENSMUST00000110457]
|
| AlphaFold |
F8VQB6 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000022882
AA Change: M630K
PolyPhen 2
Score 0.994 (Sensitivity: 0.69; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000022882
Gene: ENSMUSG00000022272
AA Change: M630K
| Domain | Start | End | E-Value | Type |
|---|
|
IQ
|
1 |
17 |
7.83e1 |
SMART |
|
IQ
|
18 |
40 |
1.06e0 |
SMART |
|
IQ
|
41 |
63 |
7.07e-2 |
SMART |
|
PDB:2LW9|B
|
136 |
171 |
7e-13 |
PDB |
|
low complexity region
|
172 |
186 |
N/A |
INTRINSIC |
|
low complexity region
|
213 |
235 |
N/A |
INTRINSIC |
|
low complexity region
|
344 |
356 |
N/A |
INTRINSIC |
|
low complexity region
|
401 |
419 |
N/A |
INTRINSIC |
|
PH
|
471 |
570 |
1.39e-21 |
SMART |
|
SCOP:d1faoa_
|
588 |
639 |
3e-6 |
SMART |
|
PH
|
651 |
757 |
6.76e-11 |
SMART |
|
MyTH4
|
805 |
953 |
4.12e-37 |
SMART |
|
B41
|
954 |
1216 |
1.72e-44 |
SMART |
|
Blast:B41
|
1218 |
1303 |
3e-45 |
BLAST |
|
low complexity region
|
1304 |
1316 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000110457
AA Change: M1376K
PolyPhen 2
Score 0.994 (Sensitivity: 0.69; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000106087
Gene: ENSMUSG00000022272
AA Change: M1376K
| Domain | Start | End | E-Value | Type |
|---|
|
MYSc
|
57 |
740 |
N/A |
SMART |
|
IQ
|
741 |
763 |
1.27e-3 |
SMART |
|
IQ
|
764 |
786 |
1.06e0 |
SMART |
|
IQ
|
787 |
809 |
7.07e-2 |
SMART |
|
Pfam:MYO10_CC
|
881 |
932 |
4.2e-22 |
PFAM |
|
low complexity region
|
959 |
981 |
N/A |
INTRINSIC |
|
low complexity region
|
1090 |
1102 |
N/A |
INTRINSIC |
|
low complexity region
|
1147 |
1165 |
N/A |
INTRINSIC |
|
PH
|
1217 |
1316 |
1.39e-21 |
SMART |
|
PH
|
1397 |
1503 |
6.76e-11 |
SMART |
|
MyTH4
|
1551 |
1699 |
4.12e-37 |
SMART |
|
B41
|
1700 |
1962 |
1.72e-44 |
SMART |
|
low complexity region
|
2050 |
2062 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 99.8%
- 3x: 99.7%
- 10x: 99.4%
- 20x: 98.9%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the myosin superfamily. The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-10 (MYH10). Unconventional myosins contain the basic domains of conventional myosins and are further distinguished from class members by their tail domains. This gene functions as an actin-based molecular motor and plays a role in integration of F-actin and microtubule cytoskeletons during meiosis. [provided by RefSeq, Dec 2011]
PHENOTYPE: Homozygous null mutations are semi-lethal with over half of homozygous embryos exhibiting exencephaly. Surviving mutants show decreased body weight, white spotting, syndactyly, persistence of hyaloid vascular system and other eye defects. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 73 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acap3 |
CCTGGGCTGCTG |
CCTGGGCTGCTGCATACTGGGCTGCTG |
4: 155,989,553 (GRCm39) |
|
probably benign |
Het |
| Adamts9 |
A |
G |
6: 92,920,126 (GRCm39) |
V4A |
possibly damaging |
Het |
| AI837181 |
GGC |
GGCTGC |
19: 5,475,260 (GRCm39) |
|
probably benign |
Het |
| Alk |
A |
G |
17: 72,202,931 (GRCm39) |
Y1135H |
probably damaging |
Het |
| Ankhd1 |
CGGCGG |
CGGCGGAGGCGG |
18: 36,693,979 (GRCm39) |
|
probably benign |
Het |
| Ano3 |
A |
C |
2: 110,527,381 (GRCm39) |
L609R |
probably benign |
Het |
| Bicc1 |
A |
G |
10: 70,771,660 (GRCm39) |
|
probably null |
Het |
| Bltp1 |
TTAT |
TTATTATTATTATTAGTAT |
3: 37,104,906 (GRCm39) |
|
probably benign |
Het |
| Card6 |
T |
C |
15: 5,129,624 (GRCm39) |
I591V |
probably benign |
Het |
| Ccdc121rt2 |
T |
A |
5: 112,597,937 (GRCm39) |
N161K |
probably benign |
Het |
| Ccdc18 |
A |
G |
5: 108,368,582 (GRCm39) |
N1235D |
probably benign |
Het |
| Cd109 |
TTAT |
TTATTTATTTATCTAT |
9: 78,619,813 (GRCm39) |
|
probably benign |
Het |
| Cnpy3 |
CCT |
CCTGCT |
17: 47,047,670 (GRCm39) |
|
probably benign |
Het |
| Col6a5 |
GCAGTC |
GCAGTCTCCAGTC |
9: 105,755,796 (GRCm39) |
|
probably null |
Het |
| Cyb5r4 |
GACACACTGCCCAGGGA |
GACACACTGCCCAGGGATGTGACACACACACTGCCCAGGGA |
9: 86,922,485 (GRCm39) |
|
probably benign |
Het |
| Cyp8b1 |
A |
T |
9: 121,744,561 (GRCm39) |
M257K |
possibly damaging |
Het |
| Dbf4 |
A |
T |
5: 8,447,985 (GRCm39) |
H408Q |
possibly damaging |
Het |
| Defb22 |
TTGCGGCA |
TTGCGGCAGAGCTGGCCTGTGCGGCA |
2: 152,327,751 (GRCm39) |
|
probably benign |
Het |
| Ercc6l2 |
A |
T |
13: 64,000,831 (GRCm39) |
T417S |
probably benign |
Het |
| Exd2 |
AGCCACAG |
A |
12: 80,522,706 (GRCm39) |
|
probably null |
Het |
| Fam171b |
GC |
GCAGCATC |
2: 83,643,239 (GRCm39) |
|
probably benign |
Het |
| Flvcr2 |
T |
A |
12: 85,793,960 (GRCm39) |
L112Q |
probably damaging |
Het |
| Flywch1 |
GTG |
GTGGGGGGAGGCTACGTACTCACCCACTCCTTTTG |
17: 23,981,149 (GRCm39) |
|
probably null |
Het |
| Gabre |
TCAGGCTCAGGCT |
TCAGGCTCAGGCTCAGGCT |
X: 71,314,022 (GRCm39) |
|
probably benign |
Het |
| Garin5a |
CCTGGGTCTGAGGGAGGA |
CCTGGGTCTGAGGGAGGACGGCTGGATCCTGGATCACTGGGTCTGAGGGAGGA |
7: 44,149,944 (GRCm39) |
|
probably null |
Het |
| Gm4884 |
C |
A |
7: 40,690,233 (GRCm39) |
P43Q |
probably damaging |
Het |
| Grm8 |
A |
G |
6: 27,363,779 (GRCm39) |
W579R |
probably damaging |
Het |
| Hsdl2 |
AG |
AGCAGCAGCCACAGCTGCCG |
4: 59,610,657 (GRCm39) |
|
probably benign |
Het |
| Ivl |
CTGCTGCTGCTGCTGT |
C |
3: 92,479,650 (GRCm39) |
|
probably benign |
Het |
| Kif18b |
T |
C |
11: 102,803,192 (GRCm39) |
D506G |
probably benign |
Het |
| Krtap28-10 |
AGCCAC |
AGCCACGGCCAC |
1: 83,019,856 (GRCm39) |
|
probably benign |
Het |
| Krtap28-10 |
GCCACAGCCACCACA |
GCCACAGCCACCACATCCACAGCCACCACA |
1: 83,019,995 (GRCm39) |
|
probably benign |
Het |
| Lama1 |
C |
A |
17: 68,088,057 (GRCm39) |
S1558R |
|
Het |
| Lcmt1 |
C |
CCGCGGGGCTT |
7: 122,969,059 (GRCm39) |
|
probably null |
Het |
| Lmna |
A |
G |
3: 88,391,361 (GRCm39) |
V494A |
probably benign |
Het |
| Mapk6 |
CCAC |
CCACCTCAC |
9: 75,295,542 (GRCm39) |
|
probably null |
Het |
| Mboat7 |
T |
A |
7: 3,694,856 (GRCm39) |
H52L |
probably damaging |
Het |
| Med12l |
CAG |
CAGAAG |
3: 59,183,387 (GRCm39) |
|
probably benign |
Het |
| Morc2a |
T |
A |
11: 3,626,191 (GRCm39) |
M225K |
probably benign |
Het |
| Mpdz |
G |
A |
4: 81,211,829 (GRCm39) |
A1566V |
possibly damaging |
Het |
| Mpi |
T |
C |
9: 57,455,924 (GRCm39) |
D186G |
probably benign |
Het |
| Mtmr12 |
C |
A |
15: 12,261,984 (GRCm39) |
N386K |
probably damaging |
Het |
| Myh3 |
ATTAC |
ATTACTTAC |
11: 66,977,182 (GRCm39) |
|
probably null |
Het |
| Nbas |
C |
T |
12: 13,329,409 (GRCm39) |
T118I |
possibly damaging |
Het |
| Nedd4l |
C |
T |
18: 65,342,751 (GRCm39) |
R755C |
probably damaging |
Het |
| Nefh |
GACTTGGCCTCACCTGGG |
GACTTGGCCTCACCTGGGTACTTGGCCTCACCTGGG |
11: 4,891,032 (GRCm39) |
|
probably benign |
Het |
| Numa1 |
T |
C |
7: 101,648,987 (GRCm39) |
L906P |
probably damaging |
Het |
| Or6s1 |
G |
A |
14: 51,308,469 (GRCm39) |
A127V |
probably damaging |
Het |
| Or7h8 |
T |
C |
9: 20,124,190 (GRCm39) |
S182P |
probably benign |
Het |
| Otop2 |
G |
T |
11: 115,214,492 (GRCm39) |
R83L |
probably benign |
Het |
| Pmm1 |
T |
A |
15: 81,842,014 (GRCm39) |
Q62L |
probably damaging |
Het |
| Pramel16 |
C |
G |
4: 143,675,478 (GRCm39) |
Q449H |
probably damaging |
Het |
| Ptprj |
A |
T |
2: 90,301,514 (GRCm39) |
L206* |
probably null |
Het |
| Rassf6 |
TC |
TCTGCCTCACTCATGGTCCTGTAGAGCATTGGGGATCC |
5: 90,756,800 (GRCm39) |
|
probably benign |
Het |
| Rps19 |
A |
AGAAAAT |
7: 24,588,605 (GRCm39) |
|
probably benign |
Het |
| Rsrp1 |
T |
A |
4: 134,651,266 (GRCm39) |
V10E |
unknown |
Het |
| Sh2d6 |
C |
T |
6: 72,493,371 (GRCm39) |
|
probably null |
Het |
| Six4 |
TG |
T |
12: 73,150,356 (GRCm39) |
|
probably null |
Het |
| Slc6a15 |
T |
A |
10: 103,236,077 (GRCm39) |
V264D |
probably damaging |
Het |
| Snapc5 |
ATGGAAGAAGAGG |
A |
9: 64,089,493 (GRCm39) |
|
probably benign |
Het |
| Sost |
A |
T |
11: 101,854,958 (GRCm39) |
I117N |
probably damaging |
Het |
| Spmip5 |
A |
G |
19: 58,777,726 (GRCm39) |
F28S |
probably damaging |
Het |
| Tbc1d22a |
AGGTGTGTG |
A |
15: 86,183,975 (GRCm39) |
|
probably null |
Het |
| Tcaf1 |
C |
T |
6: 42,656,107 (GRCm39) |
V290I |
probably benign |
Het |
| Tcof1 |
GCA |
GCACCA |
18: 60,968,815 (GRCm39) |
|
probably benign |
Het |
| Tex55 |
T |
C |
16: 38,648,363 (GRCm39) |
T249A |
probably benign |
Het |
| Tgfbr1 |
A |
G |
4: 47,353,354 (GRCm39) |
I15V |
unknown |
Het |
| Tmem241 |
A |
T |
18: 12,116,618 (GRCm39) |
L288Q |
probably damaging |
Het |
| Tnfrsf13b |
T |
G |
11: 61,032,270 (GRCm39) |
V100G |
probably benign |
Het |
| Trim66 |
A |
G |
7: 109,059,960 (GRCm39) |
S809P |
probably damaging |
Het |
| Tubb4a |
C |
G |
17: 57,394,464 (GRCm39) |
G17A |
possibly damaging |
Het |
| Txndc16 |
A |
G |
14: 45,406,795 (GRCm39) |
V220A |
probably benign |
Het |
| Zan |
T |
A |
5: 137,389,982 (GRCm39) |
Q4830L |
unknown |
Het |
|
| Other mutations in Myo10 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00557:Myo10
|
APN |
15 |
25,776,466 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01068:Myo10
|
APN |
15 |
25,739,395 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL01352:Myo10
|
APN |
15 |
25,701,783 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01388:Myo10
|
APN |
15 |
25,736,703 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
IGL01460:Myo10
|
APN |
15 |
25,714,194 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01553:Myo10
|
APN |
15 |
25,776,415 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01732:Myo10
|
APN |
15 |
25,732,149 (GRCm39) |
missense |
probably benign |
0.10 |
|
IGL01992:Myo10
|
APN |
15 |
25,799,634 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL02000:Myo10
|
APN |
15 |
25,808,152 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02045:Myo10
|
APN |
15 |
25,726,574 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL02307:Myo10
|
APN |
15 |
25,776,401 (GRCm39) |
splice site |
probably benign |
|
|
IGL02511:Myo10
|
APN |
15 |
25,723,975 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL03240:Myo10
|
APN |
15 |
25,701,688 (GRCm39) |
missense |
probably damaging |
1.00 |
|
least
|
UTSW |
15 |
25,726,561 (GRCm39) |
nonsense |
probably null |
|
|
R0037:Myo10
|
UTSW |
15 |
25,666,618 (GRCm39) |
intron |
probably benign |
|
|
R0153:Myo10
|
UTSW |
15 |
25,781,324 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R0282:Myo10
|
UTSW |
15 |
25,793,253 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0360:Myo10
|
UTSW |
15 |
25,804,454 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0585:Myo10
|
UTSW |
15 |
25,736,541 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0617:Myo10
|
UTSW |
15 |
25,738,091 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0729:Myo10
|
UTSW |
15 |
25,722,243 (GRCm39) |
splice site |
probably benign |
|
|
R0771:Myo10
|
UTSW |
15 |
25,778,264 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0960:Myo10
|
UTSW |
15 |
25,801,275 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1562:Myo10
|
UTSW |
15 |
25,780,497 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R1651:Myo10
|
UTSW |
15 |
25,742,455 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1789:Myo10
|
UTSW |
15 |
25,726,611 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1816:Myo10
|
UTSW |
15 |
25,800,286 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1835:Myo10
|
UTSW |
15 |
25,805,673 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R1908:Myo10
|
UTSW |
15 |
25,801,308 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2082:Myo10
|
UTSW |
15 |
25,786,079 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2101:Myo10
|
UTSW |
15 |
25,722,345 (GRCm39) |
missense |
probably benign |
0.26 |
|
R2129:Myo10
|
UTSW |
15 |
25,781,885 (GRCm39) |
missense |
probably benign |
0.09 |
|
R2141:Myo10
|
UTSW |
15 |
25,714,194 (GRCm39) |
missense |
probably benign |
|
|
R2142:Myo10
|
UTSW |
15 |
25,714,194 (GRCm39) |
missense |
probably benign |
|
|
R2920:Myo10
|
UTSW |
15 |
25,801,226 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2938:Myo10
|
UTSW |
15 |
25,795,803 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3723:Myo10
|
UTSW |
15 |
25,803,374 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3852:Myo10
|
UTSW |
15 |
25,779,712 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4162:Myo10
|
UTSW |
15 |
25,726,501 (GRCm39) |
splice site |
probably null |
|
|
R4163:Myo10
|
UTSW |
15 |
25,726,501 (GRCm39) |
splice site |
probably null |
|
|
R4164:Myo10
|
UTSW |
15 |
25,726,501 (GRCm39) |
splice site |
probably null |
|
|
R4177:Myo10
|
UTSW |
15 |
25,734,137 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R4409:Myo10
|
UTSW |
15 |
25,807,955 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4667:Myo10
|
UTSW |
15 |
25,793,239 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R4905:Myo10
|
UTSW |
15 |
25,800,298 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4933:Myo10
|
UTSW |
15 |
25,781,204 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4968:Myo10
|
UTSW |
15 |
25,808,270 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5081:Myo10
|
UTSW |
15 |
25,786,026 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5123:Myo10
|
UTSW |
15 |
25,726,569 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5310:Myo10
|
UTSW |
15 |
25,778,164 (GRCm39) |
splice site |
probably null |
|
|
R6073:Myo10
|
UTSW |
15 |
25,736,728 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6117:Myo10
|
UTSW |
15 |
25,805,745 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6185:Myo10
|
UTSW |
15 |
25,726,596 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6749:Myo10
|
UTSW |
15 |
25,714,196 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6819:Myo10
|
UTSW |
15 |
25,781,496 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R6875:Myo10
|
UTSW |
15 |
25,805,745 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6908:Myo10
|
UTSW |
15 |
25,804,469 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6963:Myo10
|
UTSW |
15 |
25,734,149 (GRCm39) |
missense |
probably benign |
0.31 |
|
R7144:Myo10
|
UTSW |
15 |
25,724,011 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7266:Myo10
|
UTSW |
15 |
25,783,067 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7380:Myo10
|
UTSW |
15 |
25,779,706 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7460:Myo10
|
UTSW |
15 |
25,807,913 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7614:Myo10
|
UTSW |
15 |
25,701,709 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7618:Myo10
|
UTSW |
15 |
25,726,561 (GRCm39) |
nonsense |
probably null |
|
|
R7717:Myo10
|
UTSW |
15 |
25,732,056 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7811:Myo10
|
UTSW |
15 |
25,804,610 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7830:Myo10
|
UTSW |
15 |
25,738,057 (GRCm39) |
nonsense |
probably null |
|
|
R7862:Myo10
|
UTSW |
15 |
25,666,522 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8232:Myo10
|
UTSW |
15 |
25,804,400 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8264:Myo10
|
UTSW |
15 |
25,800,195 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8377:Myo10
|
UTSW |
15 |
25,804,481 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8385:Myo10
|
UTSW |
15 |
25,804,484 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8426:Myo10
|
UTSW |
15 |
25,799,576 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8439:Myo10
|
UTSW |
15 |
25,725,158 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8696:Myo10
|
UTSW |
15 |
25,799,572 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8775:Myo10
|
UTSW |
15 |
25,800,145 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8775-TAIL:Myo10
|
UTSW |
15 |
25,800,145 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8970:Myo10
|
UTSW |
15 |
25,803,467 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R9024:Myo10
|
UTSW |
15 |
25,793,295 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R9196:Myo10
|
UTSW |
15 |
25,805,716 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9224:Myo10
|
UTSW |
15 |
25,808,081 (GRCm39) |
missense |
probably benign |
0.33 |
|
R9308:Myo10
|
UTSW |
15 |
25,781,862 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9358:Myo10
|
UTSW |
15 |
25,781,520 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R9606:Myo10
|
UTSW |
15 |
25,776,401 (GRCm39) |
frame shift |
probably null |
|
|
R9722:Myo10
|
UTSW |
15 |
25,801,227 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Myo10
|
UTSW |
15 |
25,799,640 (GRCm39) |
critical splice donor site |
probably null |
|
|
Z1177:Myo10
|
UTSW |
15 |
25,781,487 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AATAGCATTCCAGTGTCTCCG -3'
(R):5'- CAAACTCCTCTGTCCAAATAACTTG -3'
Sequencing Primer
(F):5'- ATTCCAGTGTCTCCGGGGAG -3'
(R):5'- CTGAAGGGATGGCTCTCACATACTG -3'
|
| Posted On |
2019-12-04 |
Incidental Mutation