Mutagenetix > Incidental Mutation

Incidental Mutation 'RF020:Cep350'

603767

Institutional Source

Beutler Lab

Gene Symbol

Cep350

Ensembl Gene

ENSMUSG00000033671

Gene Name

centrosomal protein 350

Synonyms

4933409L06Rik, 6430546F08Rik

Accession Numbers

Essential gene?

Probably essential (E-score: 0.961) question?

Stock #

RF020 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

155720710-155849001 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 155791224 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Valine to Glutamic Acid at position 1300 (V1300E)

Ref Sequence

ENSEMBL: ENSMUSP00000120085 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000138762]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000138762
AA Change: V1300E

PolyPhen 2 Score 0.336 (Sensitivity: 0.90; Specificity: 0.89)

SMART Domains

Protein: ENSMUSP00000120085
Gene: ENSMUSG00000033671
AA Change: V1300E

Domain	Start	End	E-Value	Type
low complexity region	251	265	N/A	INTRINSIC
low complexity region	376	394	N/A	INTRINSIC
low complexity region	481	491	N/A	INTRINSIC
coiled coil region	596	641	N/A	INTRINSIC
low complexity region	659	669	N/A	INTRINSIC
low complexity region	701	719	N/A	INTRINSIC
low complexity region	754	763	N/A	INTRINSIC
low complexity region	979	994	N/A	INTRINSIC
low complexity region	1153	1175	N/A	INTRINSIC
low complexity region	1250	1267	N/A	INTRINSIC
coiled coil region	1363	1402	N/A	INTRINSIC
low complexity region	1517	1531	N/A	INTRINSIC
low complexity region	1536	1546	N/A	INTRINSIC
low complexity region	1694	1714	N/A	INTRINSIC
coiled coil region	1732	1794	N/A	INTRINSIC
low complexity region	1800	1811	N/A	INTRINSIC
low complexity region	1819	1835	N/A	INTRINSIC
coiled coil region	1853	1893	N/A	INTRINSIC
low complexity region	1980	1994	N/A	INTRINSIC
coiled coil region	2042	2092	N/A	INTRINSIC
low complexity region	2383	2394	N/A	INTRINSIC
low complexity region	2409	2421	N/A	INTRINSIC
low complexity region	2470	2482	N/A	INTRINSIC
CAP_GLY	2486	2551	5.91e-31	SMART
coiled coil region	2700	2731	N/A	INTRINSIC

Coding Region Coverage

1x: 99.8%
3x: 99.7%
10x: 99.3%
20x: 98.5%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The product of this gene is a large protein with a CAP-Gly domain typically found in cytoskeleton-associated proteins. The encoded protein primarily localizes to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. The encoded protein directly interacts with another large centrosomal protein and is required to anchor microtubules at the centrosome. It is also implicated in the regulation of a class of nuclear hormone receptors in the nucleus. Several alternatively spliced transcript variants have been found, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]

Allele List at MGI

All alleles(5) : Gene trapped(5)

Other mutations in this stock

Total: 90 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca16	A	G	7: 120,132,880 (GRCm39)	K1270E	possibly damaging	Het
Adgrb2	T	C	4: 129,903,877 (GRCm39)	S668P	probably damaging	Het
Ahdc1	T	G	4: 132,791,588 (GRCm39)	L943R	possibly damaging	Het
Ank2	T	C	3: 126,739,125 (GRCm39)	K2253R	unknown	Het
Arhgap23	T	C	11: 97,354,387 (GRCm39)	S767P	probably damaging	Het
Arhgef12	A	G	9: 42,901,285 (GRCm39)	I839T	possibly damaging	Het
Begain	CGCCGC	CGCCGCGGCCGC	12: 108,999,350 (GRCm39)		probably benign	Het
Btbd19	A	T	4: 116,979,472 (GRCm39)	C116S	probably damaging	Het
Cbr1	C	T	16: 93,407,067 (GRCm39)	A261V	probably benign	Het
Ccdc137	A	G	11: 120,349,022 (GRCm39)	R18G	probably benign	Het
Cdsn	AG	AGACAGGAAGTAGTAGCTCTCAG	17: 35,865,876 (GRCm39)		probably benign	Het
Celsr3	C	T	9: 108,726,256 (GRCm39)	R3162C	probably benign	Het
Cluh	G	GCCAGAT	11: 74,560,364 (GRCm39)		probably benign	Het
Cmya5	G	T	13: 93,205,799 (GRCm39)	Q3357K	possibly damaging	Het
Col6a2	T	G	10: 76,442,043 (GRCm39)		probably null	Het
Cyp2j9	T	A	4: 96,465,889 (GRCm39)	T315S	probably damaging	Het
Cyp3a13	CATTATT	CATT	5: 137,892,525 (GRCm39)		probably null	Het
Dnah6	T	A	6: 73,095,040 (GRCm39)	Y2181F	probably benign	Het
Dnah7b	A	G	1: 46,412,421 (GRCm39)	D4010G	possibly damaging	Het
E4f1	CCG	CCGACG	17: 24,674,169 (GRCm39)		probably benign	Het
Ep300	A	T	15: 81,470,772 (GRCm39)		probably benign	Het
Fam234a	A	G	17: 26,437,725 (GRCm39)	V90A	probably benign	Het
Gab3	TCT	TCTGCT	X: 74,043,623 (GRCm39)		probably benign	Het
Gal3st1	A	G	11: 3,948,153 (GRCm39)	Y120C	possibly damaging	Het
Garin5a	GGA	GGAAGGGTGGATCCTGGATACCTGGGTCTGAGGGAAGA	7: 44,149,959 (GRCm39)		probably null	Het
Gm5475	GTGGAAGGAAAGGT	G	15: 100,325,030 (GRCm39)		probably null	Het
Gm6665	T	TC	18: 31,953,430 (GRCm39)		probably null	Het
Hdlbp	T	C	1: 93,368,456 (GRCm39)	T8A	probably benign	Het
Hnrnpa2b1	T	A	6: 51,443,674 (GRCm39)	K92N	probably damaging	Het
Hsdl2	GGAGCAGCCACAGCTGCAGGAGAAGCCACAGCTGCAGGAGCAGCCACAGC	GGAGCAGCCACAGCTGCAGGAGCAGCCACAGCTGCAGGAGAAGCCACAGCTGCAGGAGCAGCCACAGC	4: 59,610,640 (GRCm39)		probably benign	Het
Klhl10	C	G	11: 100,332,896 (GRCm39)	Q14E	probably benign	Het
Klra2	GAAAGAAATCCA	GAAAGAAATCCAAAGAAATCCA	6: 131,198,801 (GRCm39)		probably null	Het
Kmt2b	CC	CCTCCTGC	7: 30,285,807 (GRCm39)		probably benign	Het
Krt1c	A	G	15: 101,726,403 (GRCm39)	I45T	unknown	Het
Ksr2	T	C	5: 117,693,283 (GRCm39)	S244P	probably benign	Het
Lama5	A	T	2: 179,837,971 (GRCm39)	M915K	probably benign	Het
Lrp1b	A	C	2: 41,660,858 (GRCm39)	H197Q		Het
Lrrc1	T	C	9: 77,359,913 (GRCm39)	E293G	probably damaging	Het
Med12l	AACA	AACAACA	3: 59,183,379 (GRCm39)		probably benign	Het
Mgam	T	A	6: 40,662,243 (GRCm39)	Y1179N	probably damaging	Het
Mgat4c	A	G	10: 102,224,928 (GRCm39)	I381V	probably benign	Het
Mrgprx1	A	AGAC	7: 47,671,259 (GRCm39)		probably benign	Het
Myc	A	T	15: 61,857,672 (GRCm39)		probably benign	Het
Nipbl	A	G	15: 8,388,418 (GRCm39)	S401P	probably damaging	Het
Nlrp9c	A	T	7: 26,084,649 (GRCm39)	I310N	probably benign	Het
Nwd2	C	A	5: 63,963,066 (GRCm39)	Y883*	probably null	Het
Oas1e	T	A	5: 120,932,383 (GRCm39)	T87S	possibly damaging	Het
Or10n7-ps1	GA	GATACA	9: 39,598,049 (GRCm39)		probably null	Het
Or51a5	A	T	7: 102,771,098 (GRCm39)	C294S	probably benign	Het
Or52d3	A	G	7: 104,229,497 (GRCm39)	M215V	probably benign	Het
Or8b38	G	A	9: 37,972,620 (GRCm39)	M1I	probably null	Het
Pappa	T	G	4: 65,123,282 (GRCm39)	S872R	possibly damaging	Het
Parp4	T	C	14: 56,884,806 (GRCm39)	L1295P	unknown	Het
Pcdh15	A	T	10: 74,021,242 (GRCm39)	Y152F	probably damaging	Het
Pdk1	A	T	2: 71,714,240 (GRCm39)	I217L	possibly damaging	Het
Phldb1	A	C	9: 44,609,243 (GRCm39)	C450W	probably damaging	Het
Pnma8a	C	CCATGATGCACCTGCTTCAACATCA	7: 16,695,376 (GRCm39)		probably benign	Het
Prl2c5	G	A	13: 13,360,497 (GRCm39)	G55S	probably benign	Het
Psme2b	A	T	11: 48,836,397 (GRCm39)	H183Q	probably damaging	Het
Ptms	CCTCCTC	CCTCCTCCTC	6: 124,891,412 (GRCm39)		probably benign	Het
Rln3	T	C	8: 84,769,931 (GRCm39)	T73A	probably benign	Het
Rprd1a	T	A	18: 24,663,062 (GRCm39)	Q21L	probably damaging	Het
Septin3	A	T	15: 82,168,662 (GRCm39)	D155V	probably damaging	Het
Sh3rf3	T	A	10: 58,649,590 (GRCm39)	V65E	probably damaging	Het
Shank3	A	G	15: 89,384,593 (GRCm39)	N155S	probably benign	Het
Shox2	G	T	3: 66,881,146 (GRCm39)	P278Q	probably damaging	Het
Slc1a1	T	C	19: 28,856,555 (GRCm39)		probably null	Het
Slc39a10	A	T	1: 46,849,175 (GRCm39)	F814I	probably damaging	Het
Slc5a1	T	C	5: 33,290,773 (GRCm39)	I119T	probably damaging	Het
Slc6a13	T	C	6: 121,301,310 (GRCm39)		probably null	Het
Spmap2l	CAGCGATCCTCCCCAGTCCCGCAAGGC	CAGCGATCCTCCCCAGTCCCGCAAGGCGAGCGATCCTCCCCAGTCCCGCAAGGC	5: 77,164,247 (GRCm39)		probably benign	Het
Spta1	A	G	1: 174,041,010 (GRCm39)	D1270G	probably benign	Het
Spta1	T	A	1: 174,045,469 (GRCm39)	F1542L	probably damaging	Het
Tacc3	T	A	5: 33,818,568 (GRCm39)	M1K	probably null	Het
Tax1bp1	T	C	6: 52,698,339 (GRCm39)	V17A	probably damaging	Het
Tmem156	T	A	5: 65,248,890 (GRCm39)	E3D	probably benign	Het
Tmem209	T	A	6: 30,487,417 (GRCm39)	M530L	probably benign	Het
Trpc2	A	G	7: 101,745,433 (GRCm39)	D883G	unknown	Het
Tsen34	GGAGCCAAAAT	G	7: 3,698,795 (GRCm39)		probably null	Het
Uhrf2	T	C	19: 30,063,791 (GRCm39)	Y585H	probably damaging	Het
Vmn1r26	T	A	6: 57,985,705 (GRCm39)	K161N	probably benign	Het
Vmn1r29	A	G	6: 58,284,528 (GRCm39)	S83G	probably benign	Het
Vps13b	G	T	15: 35,925,552 (GRCm39)	W3829L	probably null	Het
Vwce	G	A	19: 10,630,449 (GRCm39)	G503R	probably damaging	Het
Zc3h11a	T	C	1: 133,554,735 (GRCm39)	E415G	possibly damaging	Het
Zc3h14	T	A	12: 98,746,541 (GRCm39)		probably null	Het
Zfp119b	A	T	17: 56,246,499 (GRCm39)	M229K	probably benign	Het
Zfp384	CCAAGCTCAAGC	CCAAGC	6: 125,013,418 (GRCm39)		probably benign	Het
Zfp384	GGCCCAGGC	GGCCCAGGCCCACGCCCAGGC	6: 125,013,451 (GRCm39)		probably benign	Het
Zyx	T	A	6: 42,334,330 (GRCm39)	L518Q	probably damaging	Het

Other mutations in Cep350

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00764:Cep350	APN	1	155,816,492 (GRCm39)	missense	possibly damaging	0.68
IGL00821:Cep350	APN	1	155,737,950 (GRCm39)	missense	probably benign
IGL00837:Cep350	APN	1	155,829,137 (GRCm39)	missense	probably damaging	1.00
IGL00977:Cep350	APN	1	155,808,611 (GRCm39)	missense	probably null	0.99
IGL01544:Cep350	APN	1	155,828,933 (GRCm39)	missense	probably damaging	1.00
IGL01616:Cep350	APN	1	155,828,993 (GRCm39)	missense	probably benign	0.00
IGL01695:Cep350	APN	1	155,819,904 (GRCm39)	missense	probably damaging	1.00
IGL01902:Cep350	APN	1	155,737,731 (GRCm39)	missense	probably damaging	1.00
IGL01977:Cep350	APN	1	155,787,714 (GRCm39)	missense	probably benign	0.01
IGL02388:Cep350	APN	1	155,829,499 (GRCm39)	missense	probably benign	0.28
IGL02475:Cep350	APN	1	155,738,341 (GRCm39)	missense	probably damaging	1.00
IGL02528:Cep350	APN	1	155,770,361 (GRCm39)	missense	probably damaging	1.00
IGL02598:Cep350	APN	1	155,738,713 (GRCm39)	missense	probably benign	0.00
IGL02676:Cep350	APN	1	155,737,977 (GRCm39)	missense	possibly damaging	0.82
IGL02728:Cep350	APN	1	155,828,968 (GRCm39)	missense	probably benign	0.02
IGL02744:Cep350	APN	1	155,807,279 (GRCm39)	missense	probably damaging	0.98
IGL02817:Cep350	APN	1	155,804,588 (GRCm39)	missense	probably damaging	1.00
IGL02892:Cep350	APN	1	155,744,552 (GRCm39)	missense	possibly damaging	0.51
IGL03156:Cep350	APN	1	155,733,788 (GRCm39)	missense	probably damaging	1.00
IGL03166:Cep350	APN	1	155,739,346 (GRCm39)	missense	possibly damaging	0.78
IGL03216:Cep350	APN	1	155,736,373 (GRCm39)	missense	probably benign	0.06
IGL03268:Cep350	APN	1	155,829,295 (GRCm39)	missense	probably benign	0.16
IGL03358:Cep350	APN	1	155,804,285 (GRCm39)	missense	probably benign
primed	UTSW	1	155,829,334 (GRCm39)	missense	probably damaging	0.98
stoked	UTSW	1	155,791,321 (GRCm39)	missense	probably benign	0.03
NA:Cep350	UTSW	1	155,834,394 (GRCm39)	missense	probably damaging	1.00
R0060:Cep350	UTSW	1	155,804,372 (GRCm39)	missense	probably damaging	1.00
R0060:Cep350	UTSW	1	155,804,372 (GRCm39)	missense	probably damaging	1.00
R0066:Cep350	UTSW	1	155,786,964 (GRCm39)	missense	probably damaging	0.99
R0066:Cep350	UTSW	1	155,786,964 (GRCm39)	missense	probably damaging	0.99
R0172:Cep350	UTSW	1	155,829,193 (GRCm39)	missense	probably benign	0.00
R0365:Cep350	UTSW	1	155,782,317 (GRCm39)	missense	probably benign	0.00
R0472:Cep350	UTSW	1	155,790,469 (GRCm39)	missense	probably damaging	0.99
R0502:Cep350	UTSW	1	155,776,629 (GRCm39)	splice site	probably null
R0538:Cep350	UTSW	1	155,724,366 (GRCm39)	missense	possibly damaging	0.80
R0547:Cep350	UTSW	1	155,777,181 (GRCm39)	splice site	probably null
R0565:Cep350	UTSW	1	155,836,941 (GRCm39)	splice site	probably benign
R0607:Cep350	UTSW	1	155,747,794 (GRCm39)	missense	probably damaging	1.00
R0645:Cep350	UTSW	1	155,816,458 (GRCm39)	splice site	probably null
R0675:Cep350	UTSW	1	155,835,499 (GRCm39)	missense	possibly damaging	0.63
R0828:Cep350	UTSW	1	155,828,992 (GRCm39)	missense	probably benign	0.00
R0863:Cep350	UTSW	1	155,737,981 (GRCm39)	missense	probably benign	0.00
R0969:Cep350	UTSW	1	155,816,572 (GRCm39)	missense	possibly damaging	0.81
R1102:Cep350	UTSW	1	155,807,264 (GRCm39)	missense	probably damaging	1.00
R1186:Cep350	UTSW	1	155,751,122 (GRCm39)	missense	probably damaging	1.00
R1552:Cep350	UTSW	1	155,786,484 (GRCm39)	missense	possibly damaging	0.92
R1560:Cep350	UTSW	1	155,804,825 (GRCm39)	missense	possibly damaging	0.48
R1698:Cep350	UTSW	1	155,829,104 (GRCm39)	missense	possibly damaging	0.62
R1729:Cep350	UTSW	1	155,787,727 (GRCm39)	missense	probably benign	0.17
R1735:Cep350	UTSW	1	155,828,960 (GRCm39)	missense	probably damaging	0.99
R1740:Cep350	UTSW	1	155,804,579 (GRCm39)	missense	probably damaging	1.00
R1783:Cep350	UTSW	1	155,804,611 (GRCm39)	missense	probably damaging	1.00
R1844:Cep350	UTSW	1	155,724,374 (GRCm39)	missense	probably damaging	0.99
R1848:Cep350	UTSW	1	155,829,397 (GRCm39)	missense	probably benign	0.28
R1988:Cep350	UTSW	1	155,808,850 (GRCm39)	missense	possibly damaging	0.82
R2008:Cep350	UTSW	1	155,790,467 (GRCm39)	missense	probably benign	0.16
R2241:Cep350	UTSW	1	155,834,302 (GRCm39)	splice site	probably null
R2245:Cep350	UTSW	1	155,754,766 (GRCm39)	missense	probably benign	0.10
R2402:Cep350	UTSW	1	155,738,882 (GRCm39)	missense	probably benign
R2566:Cep350	UTSW	1	155,835,464 (GRCm39)	critical splice donor site	probably null
R3160:Cep350	UTSW	1	155,738,910 (GRCm39)	missense	probably benign	0.00
R3162:Cep350	UTSW	1	155,738,910 (GRCm39)	missense	probably benign	0.00
R3769:Cep350	UTSW	1	155,828,950 (GRCm39)	missense	probably damaging	1.00
R4035:Cep350	UTSW	1	155,835,541 (GRCm39)	missense	probably benign	0.06
R4158:Cep350	UTSW	1	155,808,621 (GRCm39)	missense	probably damaging	1.00
R4160:Cep350	UTSW	1	155,808,621 (GRCm39)	missense	probably damaging	1.00
R4213:Cep350	UTSW	1	155,811,707 (GRCm39)	missense	probably damaging	1.00
R4483:Cep350	UTSW	1	155,802,214 (GRCm39)	missense	probably benign	0.01
R4648:Cep350	UTSW	1	155,778,344 (GRCm39)	missense	possibly damaging	0.85
R4694:Cep350	UTSW	1	155,804,332 (GRCm39)	missense	probably damaging	1.00
R4836:Cep350	UTSW	1	155,804,579 (GRCm39)	missense	probably damaging	1.00
R4839:Cep350	UTSW	1	155,804,240 (GRCm39)	missense	probably benign	0.00
R4969:Cep350	UTSW	1	155,736,025 (GRCm39)	missense	probably damaging	0.99
R5014:Cep350	UTSW	1	155,803,952 (GRCm39)	missense	probably benign	0.00
R5027:Cep350	UTSW	1	155,809,100 (GRCm39)	missense	probably benign	0.01
R5144:Cep350	UTSW	1	155,786,896 (GRCm39)	missense	probably damaging	0.99
R5153:Cep350	UTSW	1	155,811,692 (GRCm39)	missense	probably damaging	1.00
R5165:Cep350	UTSW	1	155,804,114 (GRCm39)	missense	probably damaging	1.00
R5182:Cep350	UTSW	1	155,733,854 (GRCm39)	missense	probably damaging	1.00
R5445:Cep350	UTSW	1	155,770,469 (GRCm39)	missense	probably benign	0.01
R5738:Cep350	UTSW	1	155,741,824 (GRCm39)	missense	probably damaging	1.00
R5809:Cep350	UTSW	1	155,809,087 (GRCm39)	missense	probably damaging	0.98
R5855:Cep350	UTSW	1	155,829,508 (GRCm39)	missense	probably benign	0.00
R6103:Cep350	UTSW	1	155,800,322 (GRCm39)	missense	probably benign	0.05
R6139:Cep350	UTSW	1	155,829,025 (GRCm39)	missense	probably benign	0.03
R6285:Cep350	UTSW	1	155,829,120 (GRCm39)	missense	possibly damaging	0.48
R6430:Cep350	UTSW	1	155,770,419 (GRCm39)	missense	probably damaging	1.00
R6446:Cep350	UTSW	1	155,737,900 (GRCm39)	missense	probably benign
R6520:Cep350	UTSW	1	155,809,082 (GRCm39)	missense	probably benign	0.02
R6712:Cep350	UTSW	1	155,733,852 (GRCm39)	missense	possibly damaging	0.93
R6940:Cep350	UTSW	1	155,804,297 (GRCm39)	missense	probably benign	0.01
R7020:Cep350	UTSW	1	155,804,077 (GRCm39)	missense	probably damaging	1.00
R7056:Cep350	UTSW	1	155,724,373 (GRCm39)	missense	probably damaging	1.00
R7141:Cep350	UTSW	1	155,790,494 (GRCm39)	missense	probably damaging	1.00
R7215:Cep350	UTSW	1	155,770,453 (GRCm39)	missense	possibly damaging	0.89
R7247:Cep350	UTSW	1	155,786,499 (GRCm39)	missense	probably damaging	1.00
R7272:Cep350	UTSW	1	155,829,334 (GRCm39)	missense	probably damaging	0.98
R7336:Cep350	UTSW	1	155,738,022 (GRCm39)	missense	probably benign	0.17
R7361:Cep350	UTSW	1	155,777,237 (GRCm39)	missense	probably damaging	1.00
R7390:Cep350	UTSW	1	155,741,833 (GRCm39)	missense	possibly damaging	0.94
R7402:Cep350	UTSW	1	155,803,961 (GRCm39)	missense	probably benign	0.00
R7428:Cep350	UTSW	1	155,770,365 (GRCm39)	missense	probably benign	0.00
R7440:Cep350	UTSW	1	155,816,518 (GRCm39)	missense	probably damaging	0.98
R7520:Cep350	UTSW	1	155,791,375 (GRCm39)	missense	probably benign	0.05
R7529:Cep350	UTSW	1	155,737,669 (GRCm39)	missense	probably benign	0.08
R7635:Cep350	UTSW	1	155,754,767 (GRCm39)	nonsense	probably null
R7806:Cep350	UTSW	1	155,737,809 (GRCm39)	missense	probably benign	0.00
R8100:Cep350	UTSW	1	155,829,148 (GRCm39)	missense	probably damaging	0.97
R8192:Cep350	UTSW	1	155,816,529 (GRCm39)	missense	possibly damaging	0.94
R8193:Cep350	UTSW	1	155,737,825 (GRCm39)	missense	probably benign	0.01
R8351:Cep350	UTSW	1	155,747,780 (GRCm39)	missense	probably damaging	0.99
R8406:Cep350	UTSW	1	155,798,164 (GRCm39)	missense	probably benign	0.00
R8451:Cep350	UTSW	1	155,747,780 (GRCm39)	missense	probably damaging	0.99
R8467:Cep350	UTSW	1	155,791,321 (GRCm39)	missense	probably benign	0.03
R8543:Cep350	UTSW	1	155,738,122 (GRCm39)	missense	probably damaging	0.98
R8714:Cep350	UTSW	1	155,736,477 (GRCm39)	missense	probably damaging	0.98
R8810:Cep350	UTSW	1	155,803,862 (GRCm39)	missense	probably damaging	1.00
R8837:Cep350	UTSW	1	155,737,518 (GRCm39)	missense	probably benign	0.09
R8933:Cep350	UTSW	1	155,739,161 (GRCm39)	missense	probably benign	0.01
R9043:Cep350	UTSW	1	155,773,228 (GRCm39)	missense	probably damaging	1.00
R9050:Cep350	UTSW	1	155,738,687 (GRCm39)	missense	possibly damaging	0.81
R9067:Cep350	UTSW	1	155,737,485 (GRCm39)	missense	probably benign	0.00
R9105:Cep350	UTSW	1	155,835,561 (GRCm39)	missense	probably damaging	1.00
R9295:Cep350	UTSW	1	155,738,051 (GRCm39)	nonsense	probably null
R9304:Cep350	UTSW	1	155,829,464 (GRCm39)	missense	probably damaging	0.98
R9456:Cep350	UTSW	1	155,744,457 (GRCm39)	missense	probably benign	0.00
R9575:Cep350	UTSW	1	155,751,113 (GRCm39)	missense	probably benign	0.03
R9715:Cep350	UTSW	1	155,751,107 (GRCm39)	missense	probably benign	0.00
R9749:Cep350	UTSW	1	155,828,985 (GRCm39)	missense	probably benign	0.02
R9758:Cep350	UTSW	1	155,770,433 (GRCm39)	missense	probably damaging	0.96
R9767:Cep350	UTSW	1	155,739,018 (GRCm39)	missense	probably benign	0.01
X0018:Cep350	UTSW	1	155,829,032 (GRCm39)	missense	probably benign	0.13

Predicted Primers

PCR Primer
(F):5'- CCCTACCACTTAGTTCGCAG -3'
(R):5'- TTCTAGTGGCTCTTCAGACAAG -3'

Sequencing Primer
(F):5'- ATGGTTTCATGGACCCCAAG -3'
(R):5'- GCTCTTCAGACAAGGGAAGATCTC -3'

Posted On

2019-12-04