|Institutional Source||Beutler Lab|
|Gene Name||coiled-coil domain containing 170|
|Is this an essential gene?||Possibly non essential (E-score: 0.327)|
|Stock #||RF023 (G1)|
|Chromosomal Location||4482502-4562231 bp(+) (GRCm38)|
|Type of Mutation||small insertion (1 aa in frame mutation)|
|DNA Base Change (assembly)||CCA to CCAACA at 4561018 bp (GRCm38)|
|Amino Acid Change|
|Ref Sequence||ENSEMBL: ENSMUSP00000115997 (fasta)|
|Gene Model||predicted gene model for transcript(s): [ENSMUST00000019901] [ENSMUST00000138112]|
|Coding Region Coverage||
|Validation Efficiency||96% (24/25)|
|MGI Phenotype||FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The function of this gene and its encoded protein is not known. Several genome-wide association studies have implicated the region around this gene to be involved in breast cancer and bone mineral density, but no link to this specific gene has been found. [provided by RefSeq, May 2010]|
|Allele List at MGI|
|Other mutations in this stock||
|Other mutations in Ccdc170||
(F):5'- ATTGTTGTTGCACTTGACCC -3'
(R):5'- AGTCACACACTATGGCTGAATTTC -3'
(F):5'- GTTGCACTTGACCCAGCAATG -3'
(R):5'- CACAACTGGAGAATCGTAC -3'