Incidental Mutation 'RF042:Morn4'
ID604893
Institutional Source Beutler Lab
Gene Symbol Morn4
Ensembl Gene ENSMUSG00000049670
Gene NameMORN repeat containing 4
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.141) question?
Stock #RF042 (G1)
Quality Score214.458
Status Not validated
Chromosome19
Chromosomal Location42074939-42086370 bp(-) (GRCm38)
Type of Mutationnonsense
DNA Base Change (assembly) GCAGTGAG to GCAGTGAGTCAGTCAGTGAG at 42076111 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000062887 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000051772]
Predicted Effect probably null
Transcript: ENSMUST00000051772
SMART Domains Protein: ENSMUSP00000062887
Gene: ENSMUSG00000049670

DomainStartEndE-ValueType
MORN 14 35 1.64e-5 SMART
MORN 37 58 4.15e-2 SMART
MORN 60 81 1.86e-4 SMART
MORN 83 104 1.84e0 SMART
Coding Region Coverage
  • 1x: 99.8%
  • 3x: 99.7%
  • 10x: 99.4%
  • 20x: 98.8%
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 46 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
5430401F13Rik AAAGGAAAAGGTGGCCAG AAAGGAAAAGGTGGCCAGCAAAAACAGGAAGGAAAAGGTGGCCAG 6: 131,552,886 probably benign Het
A030005L19Rik GCTGCTG GCTGCTGTGACTGCTG 1: 82,913,584 probably benign Het
AI837181 GGC GGCTGC 19: 5,425,217 probably benign Het
AI837181 CG CGGTG 19: 5,425,237 probably benign Het
Anapc2 GCGGCGGCGGCGAC GC 2: 25,272,561 probably benign Het
Cgnl1 AGCG AGCGGCG 9: 71,724,715 probably benign Het
Cntnap1 TTT TTTTGTT 11: 101,180,305 probably benign Het
Cul9 TTCTC TTC 17: 46,540,615 probably null Het
Dnmt1 GGGGCGGAGCACAGTTCCTACCTCGTT GGGGCGGAGCACAGTTCCTACCTCGTTTTGTGGGCGGAGCACAGTTCCTACCTCGTT 9: 20,910,119 probably null Het
Frem3 GATC GATCATC 8: 80,615,238 probably benign Het
Gab3 TCT TCTACT X: 75,000,005 probably benign Het
Gab3 TTC TTCGTC X: 75,000,022 probably benign Het
Gabre GGCTCC GGCTCCTGCTCC X: 72,270,047 probably benign Het
Gm8369 TGTG TGTGAGTG 19: 11,511,773 probably null Het
Gm8369 GTGTGT GTGTGTTTGTGT 19: 11,511,778 probably benign Het
Gykl1 G A 18: 52,694,416 R232Q probably benign Het
Igkv12-89 G GCAACGCCAT 6: 68,835,286 probably benign Het
Iqcf4 TCCTTTTCCTTTTCCTTTT TCCTTTTCCTTTTCCTTTTCCTTTTCCTTTTCCTTTGCCTTTTCCTTTTCCTTTT 9: 106,570,605 probably benign Het
Kmt2e TTT TTTTCTT 5: 23,478,509 probably benign Het
Krtap28-10 CCACAG CCACAGACACAG 1: 83,042,125 probably benign Het
Las1l CTTCCT CTTCCTTTTCCT X: 95,940,620 probably benign Het
Lca5l GCCCTGGCCCTGGCCCC GCCC 16: 96,159,297 probably null Het
Lce1m CACTGCTGCTGC CACTGCTGCTGCAACTGCTGCTGC 3: 93,018,139 probably benign Het
Lypd8 CA CAGTTCCCTCGCCTCTGTTACCCCACAAATCACCAATA 11: 58,390,243 probably benign Het
Mamld1 GCAACA GCAACAACA X: 71,118,812 probably benign Het
Mamld1 A AGCC X: 71,118,853 probably benign Het
Map1a T TTGCTCCACCTCCAGCTCCAGCTCCAGCTCC 2: 121,306,287 probably benign Het
Med12l GCAACA GCAACAACA 3: 59,275,956 probably benign Het
Med12l AGC AGCGGC 3: 59,275,967 probably benign Het
Med12l CAG CAGAAG 3: 59,275,981 probably benign Het
Med12l GC GCATC 3: 59,275,995 probably benign Het
Nusap1 GAGA GAGATACACGTTAGCAGTGAGGAGCAAGCTTAGA 2: 119,627,607 probably null Het
Opa3 GCGGGC GCGGGCGGAGCTGCGGGCGGAGCTGCGGGCGGAGCTACGGGC 7: 19,255,669 probably benign Het
Pdia4 CTCTTCCTCCT C 6: 47,808,306 probably null Het
Reep1 CGCCA CGCCAGCCA 6: 71,707,966 probably null Het
Sbp AAGA AAGACGCTGACAACAGAGA 17: 23,945,384 probably benign Het
Sfswap CTCGGCCCA CTCGGCCCAGTCGGCCCA 5: 129,569,743 probably benign Het
Slc39a4 TC TCATCATGATCACCATGGTCACCATGATCACTGTGGCC 15: 76,614,871 probably benign Het
Srpk2 ATCCT AT 5: 23,525,575 probably benign Het
Tfeb GCA GCACCA 17: 47,786,097 probably benign Het
Tgoln1 T TCACCTCCCGTGGGCTTGCCAGAAG 6: 72,616,074 probably benign Het
Tob1 CACA CACAACA 11: 94,214,451 probably benign Het
Trappc9 A AGCTGCTGCTGCTGCT 15: 72,801,283 probably benign Het
Tsen2 GGA GGATGA 6: 115,560,067 probably benign Het
Zfhx3 GC GCCACAGCAAC 8: 108,956,088 probably benign Het
Zfhx3 CAGCAGCA CAGCAGCAAAAGCAGCA 8: 108,956,098 probably benign Het
Other mutations in Morn4
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00971:Morn4 APN 19 42076120 missense possibly damaging 0.53
IGL02572:Morn4 APN 19 42076447 splice site probably benign
IGL02933:Morn4 APN 19 42076222 missense probably benign 0.01
FR4449:Morn4 UTSW 19 42076109 small insertion probably benign
FR4548:Morn4 UTSW 19 42076109 small insertion probably benign
R1997:Morn4 UTSW 19 42076538 missense possibly damaging 0.71
R2239:Morn4 UTSW 19 42078032 missense possibly damaging 0.93
R4409:Morn4 UTSW 19 42078547 missense possibly damaging 0.53
R5544:Morn4 UTSW 19 42076247 missense possibly damaging 0.71
R5695:Morn4 UTSW 19 42076117 missense possibly damaging 0.96
R6986:Morn4 UTSW 19 42078014 missense possibly damaging 0.71
R7024:Morn4 UTSW 19 42078044 missense possibly damaging 0.92
RF025:Morn4 UTSW 19 42076111 nonsense probably null
RF030:Morn4 UTSW 19 42076111 nonsense probably null
RF036:Morn4 UTSW 19 42076114 nonsense probably null
RF040:Morn4 UTSW 19 42076111 nonsense probably null
RF044:Morn4 UTSW 19 42076114 nonsense probably null
RF057:Morn4 UTSW 19 42076106 nonsense probably null
X0063:Morn4 UTSW 19 42077968 missense possibly damaging 0.71
Predicted Primers PCR Primer
(F):5'- GAAGGACATAACTGCCGCAG -3'
(R):5'- TGAGCGGAAACATTAATGCCCTC -3'

Sequencing Primer
(F):5'- GGCCAAACCCCTCCACAC -3'
(R):5'- GGAAACATTAATGCCCTCTCCCTC -3'
Posted On2019-12-04