Mutagenetix > Incidental Mutation

Incidental Mutation 'R7834:Tenm2'

605871

Institutional Source

Beutler Lab

Gene Symbol

Tenm2

Ensembl Gene

ENSMUSG00000049336

Gene Name

teneurin transmembrane protein 2

Synonyms

2610040L17Rik, 9330187F13Rik, D3Bwg1534e, Ten-m2, Odz2

MMRRC Submission

045888-MU

Accession Numbers

Essential gene?

Possibly essential (E-score: 0.514) question?

Stock #

R7834 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

36006656-37235964 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 36024854 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Leucine to Proline at position 1951 (L1951P)

Ref Sequence

ENSEMBL: ENSMUSP00000129951 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000057207] [ENSMUST00000102801] [ENSMUST00000163524]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000057207
AA Change: L1952P

PolyPhen 2 Score 0.991 (Sensitivity: 0.71; Specificity: 0.97)

SMART Domains

Protein: ENSMUSP00000052014
Gene: ENSMUSG00000049336
AA Change: L1952P

Domain	Start	End	E-Value	Type
Pfam:Ten_N	10	374	4.9e-177	PFAM
transmembrane domain	375	397	N/A	INTRINSIC
EGF	575	603	5.62e0	SMART
EGF_like	606	634	4.93e1	SMART
EGF	639	668	1.76e1	SMART
EGF	671	700	1.43e-1	SMART
EGF	705	735	1.2e1	SMART
EGF	738	766	9.63e0	SMART
EGF	769	797	1.25e1	SMART
EGF	800	832	1.4e0	SMART
low complexity region	1459	1475	N/A	INTRINSIC
low complexity region	2219	2230	N/A	INTRINSIC
Pfam:Tox-GHH	2681	2758	1.4e-34	PFAM

Predicted Effect

probably damaging
Transcript: ENSMUST00000102801
AA Change: L1951P

PolyPhen 2 Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)

SMART Domains

Protein: ENSMUSP00000099865
Gene: ENSMUSG00000049336
AA Change: L1951P

Domain	Start	End	E-Value	Type
Pfam:Ten_N	9	374	2e-186	PFAM
transmembrane domain	375	397	N/A	INTRINSIC
EGF	575	603	5.62e0	SMART
EGF_like	606	634	4.93e1	SMART
EGF	639	668	1.76e1	SMART
EGF	671	700	1.43e-1	SMART
EGF	705	735	1.2e1	SMART
EGF	737	765	9.63e0	SMART
EGF	768	796	1.25e1	SMART
EGF	799	831	1.4e0	SMART
low complexity region	1458	1474	N/A	INTRINSIC
low complexity region	2218	2229	N/A	INTRINSIC
Pfam:Tox-GHH	2679	2757	2e-34	PFAM

Predicted Effect

probably damaging
Transcript: ENSMUST00000163524
AA Change: L1951P

PolyPhen 2 Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)

SMART Domains

Protein: ENSMUSP00000129951
Gene: ENSMUSG00000049336
AA Change: L1951P

Domain	Start	End	E-Value	Type
Pfam:Ten_N	9	374	2e-186	PFAM
transmembrane domain	375	397	N/A	INTRINSIC
EGF	575	603	5.62e0	SMART
EGF_like	606	634	4.93e1	SMART
EGF	639	668	1.76e1	SMART
EGF	671	700	1.43e-1	SMART
EGF	705	735	1.2e1	SMART
EGF	737	765	9.63e0	SMART
EGF	768	796	1.25e1	SMART
EGF	799	831	1.4e0	SMART
low complexity region	1458	1474	N/A	INTRINSIC
low complexity region	2218	2229	N/A	INTRINSIC
Pfam:Tox-GHH	2679	2757	2e-34	PFAM

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.7%
20x: 99.1%

Validation Efficiency

100% (75/75)

MGI Phenotype

PHENOTYPE: Mice homozygous for a null allele show abnormalities in the laterality and mapping of ipsilateral retinal projections that lead to loss of ipsilateral drive, defects in binocular vision, and impaired performance on a visual discrimination task. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 74 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abcb11	A	T	2: 69,284,724 (GRCm38)	I626N	probably damaging	Het
Abcc12	C	T	8: 86,558,230 (GRCm38)	C252Y	probably damaging	Het
Abcc12	T	A	8: 86,531,550 (GRCm38)	Y779F	possibly damaging	Het
Adam22	A	T	5: 8,130,535 (GRCm38)	C521S	probably damaging	Het
Adcy5	C	A	16: 35,157,200 (GRCm38)	H368N	probably benign	Het
Akap13	T	A	7: 75,742,642 (GRCm38)	I2411N	possibly damaging	Het
Ankrd12	A	G	17: 65,987,352 (GRCm38)	F339S	probably damaging	Het
Bmp1	T	A	14: 70,508,565 (GRCm38)	R153W	probably damaging	Het
Bmp6	T	C	13: 38,469,667 (GRCm38)	F237L	probably damaging	Het
Cacna1c	A	G	6: 118,610,581 (GRCm38)	S1628P		Het
Ccdc141	T	C	2: 77,059,545 (GRCm38)	R468G	possibly damaging	Het
Cdc40	A	T	10: 40,882,949 (GRCm38)	S43T	probably benign	Het
Celf4	A	G	18: 25,753,485 (GRCm38)	M48T	probably benign	Het
Clec4g	A	T	8: 3,716,500 (GRCm38)	M267K	probably damaging	Het
Col6a1	G	T	10: 76,709,928 (GRCm38)	S903R	unknown	Het
Creg2	A	G	1: 39,650,634 (GRCm38)	F103L	probably damaging	Het
Cul9	T	C	17: 46,525,704 (GRCm38)		probably null	Het
Dchs1	G	A	7: 105,765,567 (GRCm38)	A756V	probably benign	Het
Diaph1	G	A	18: 37,853,709 (GRCm38)		probably benign	Het
Dmxl1	G	A	18: 49,920,977 (GRCm38)	G2550D	probably damaging	Het
Dst	G	T	1: 34,194,105 (GRCm38)	R3396I	probably benign	Het
Dync2h1	T	C	9: 7,118,953 (GRCm38)	T2171A	probably benign	Het
Fgd2	C	T	17: 29,364,951 (GRCm38)	T113M	probably damaging	Het
Galnt6	G	T	15: 100,714,103 (GRCm38)	S219R	probably damaging	Het
Gbp6	T	A	5: 105,273,265 (GRCm38)	E558V	probably benign	Het
Gnas	A	T	2: 174,298,990 (GRCm38)	K377*	probably null	Het
Hars2	T	C	18: 36,789,581 (GRCm38)	I389T	probably damaging	Het
Hsp90ab1	T	C	17: 45,571,165 (GRCm38)	I123V	possibly damaging	Het
Igkv6-14	A	T	6: 70,435,008 (GRCm38)	N97K	possibly damaging	Het
Isg20	T	C	7: 78,920,119 (GRCm38)	L168P	probably damaging	Het
Kcna1	C	T	6: 126,642,740 (GRCm38)	D206N	probably benign	Het
Kcnn3	A	G	3: 89,521,354 (GRCm38)	I296V	probably damaging	Het
Kif18a	G	A	2: 109,296,774 (GRCm38)	R351H	probably damaging	Het
Klra5	A	T	6: 129,899,290 (GRCm38)		probably null	Het
Krt9	T	C	11: 100,192,666 (GRCm38)	T180A	probably benign	Het
Lhx8	T	C	3: 154,311,537 (GRCm38)	S323G	probably null	Het
Lpcat2	T	A	8: 92,918,101 (GRCm38)	L506H	possibly damaging	Het
Map2	A	G	1: 66,416,488 (GRCm38)	E1447G	probably damaging	Het
Mapk8ip2	A	T	15: 89,461,373 (GRCm38)	I779F	probably damaging	Het
Mcmdc2	G	A	1: 9,912,174 (GRCm38)		probably null	Het
Mrps15	G	A	4: 126,055,389 (GRCm38)	E217K	probably damaging	Het
Muc5b	G	A	7: 141,859,070 (GRCm38)	G1918R	unknown	Het
Mug2	T	C	6: 122,036,282 (GRCm38)	I336T	probably benign	Het
Myh10	T	C	11: 68,785,826 (GRCm38)	V878A	probably damaging	Het
Nomo1	T	C	7: 46,056,738 (GRCm38)		probably null	Het
Ogdhl	T	A	14: 32,340,709 (GRCm38)	I584N	probably benign	Het
Pdzrn3	G	A	6: 101,151,195 (GRCm38)	R837C	probably damaging	Het
Pkhd1	A	G	1: 20,312,049 (GRCm38)	M2626T	probably benign	Het
Plat	G	T	8: 22,772,232 (GRCm38)	G91W	probably damaging	Het
Pml	C	A	9: 58,234,685 (GRCm38)	R288L	probably benign	Het
Pnliprp2	T	C	19: 58,774,159 (GRCm38)	S399P	probably benign	Het
Prelp	T	C	1: 133,914,772 (GRCm38)	T212A	probably damaging	Het
Ptpn13	T	A	5: 103,462,148 (GRCm38)	S4T	probably damaging	Het
Ptprb	A	C	10: 116,339,424 (GRCm38)	E821A	probably benign	Het
Rabgap1	T	C	2: 37,469,407 (GRCm38)		probably benign	Het
Reln	C	T	5: 22,039,635 (GRCm38)	V782M	possibly damaging	Het
Rpl3l	T	C	17: 24,733,463 (GRCm38)	V52A	possibly damaging	Het
Rrp1b	T	C	17: 32,051,724 (GRCm38)	V219A	probably benign	Het
Rtn1	T	A	12: 72,304,032 (GRCm38)	I468F	probably damaging	Het
Safb	T	A	17: 56,593,881 (GRCm38)	M129K	unknown	Het
Sall1	C	A	8: 89,033,374 (GRCm38)	S34I	probably benign	Het
Slc2a8	C	T	2: 32,976,907 (GRCm38)	G227D	probably damaging	Het
Slco4a1	G	T	2: 180,465,677 (GRCm38)	V295L	probably benign	Het
Slfn5	A	T	11: 82,960,452 (GRCm38)	Q525L	possibly damaging	Het
Speg	C	T	1: 75,384,927 (GRCm38)	T195M	probably damaging	Het
Syne2	A	T	12: 75,967,247 (GRCm38)	T3071S	probably benign	Het
Syngr1	G	T	15: 80,111,617 (GRCm38)	W119L	probably damaging	Het
Ulk4	C	T	9: 121,263,668 (GRCm38)	E168K	possibly damaging	Het
Ush2a	G	A	1: 188,733,440 (GRCm38)	W2735*	probably null	Het
Usp17lb	T	A	7: 104,841,511 (GRCm38)	T70S	probably damaging	Het
Vmn2r6	T	G	3: 64,538,022 (GRCm38)	N761H	probably damaging	Het
Vps13d	A	T	4: 145,108,573 (GRCm38)	I2741K		Het
Wdr38	A	T	2: 39,000,184 (GRCm38)	Q110L	possibly damaging	Het
Zfp872	A	G	9: 22,200,110 (GRCm38)	K295R	probably damaging	Het

Other mutations in Tenm2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00161:Tenm2	APN	11	36,206,899 (GRCm38)	splice site	probably benign
IGL00834:Tenm2	APN	11	36,024,258 (GRCm38)	missense	probably damaging	1.00
IGL00911:Tenm2	APN	11	36,008,733 (GRCm38)	nonsense	probably null
IGL00937:Tenm2	APN	11	36,024,623 (GRCm38)	missense	probably damaging	1.00
IGL01154:Tenm2	APN	11	36,041,544 (GRCm38)	missense	probably damaging	1.00
IGL01313:Tenm2	APN	11	36,024,248 (GRCm38)	missense	probably damaging	0.98
IGL01346:Tenm2	APN	11	36,027,405 (GRCm38)	nonsense	probably null
IGL01539:Tenm2	APN	11	36,106,827 (GRCm38)	missense	possibly damaging	0.89
IGL01629:Tenm2	APN	11	36,864,884 (GRCm38)	missense	probably damaging	0.98
IGL01780:Tenm2	APN	11	36,046,941 (GRCm38)	missense	probably benign
IGL01821:Tenm2	APN	11	36,023,883 (GRCm38)	missense	probably damaging	0.98
IGL01988:Tenm2	APN	11	36,027,251 (GRCm38)	missense	probably damaging	1.00
IGL02002:Tenm2	APN	11	36,207,095 (GRCm38)	missense	probably benign
IGL02449:Tenm2	APN	11	36,023,622 (GRCm38)	missense	probably damaging	0.99
IGL02505:Tenm2	APN	11	36,051,916 (GRCm38)	nonsense	probably null
IGL02649:Tenm2	APN	11	36,207,085 (GRCm38)	missense	possibly damaging	0.85
IGL02688:Tenm2	APN	11	36,068,458 (GRCm38)	missense	probably benign	0.05
IGL02801:Tenm2	APN	11	36,047,030 (GRCm38)	nonsense	probably null
IGL02928:Tenm2	APN	11	36,027,170 (GRCm38)	missense	possibly damaging	0.69
IGL02940:Tenm2	APN	11	36,041,644 (GRCm38)	missense	probably damaging	1.00
IGL03202:Tenm2	APN	11	36,024,548 (GRCm38)	missense	probably damaging	1.00
IGL03213:Tenm2	APN	11	36,023,330 (GRCm38)	missense	probably benign	0.05
IGL03276:Tenm2	APN	11	36,072,776 (GRCm38)	missense	possibly damaging	0.95
IGL03296:Tenm2	APN	11	36,052,025 (GRCm38)	splice site	probably null
IGL03381:Tenm2	APN	11	36,068,411 (GRCm38)	missense	probably benign	0.01
IGL03398:Tenm2	APN	11	36,024,543 (GRCm38)	missense	probably damaging	1.00
browser	UTSW	11	36,046,765 (GRCm38)	critical splice donor site	probably null
mosaic	UTSW	11	36,063,775 (GRCm38)	critical splice donor site	probably null
IGL02799:Tenm2	UTSW	11	36,273,408 (GRCm38)	missense	probably damaging	1.00
PIT4260001:Tenm2	UTSW	11	36,163,730 (GRCm38)	missense	probably damaging	1.00
PIT4382001:Tenm2	UTSW	11	36,063,902 (GRCm38)	missense	probably damaging	0.99
R0004:Tenm2	UTSW	11	36,023,357 (GRCm38)	missense	probably damaging	1.00
R0420:Tenm2	UTSW	11	36,207,124 (GRCm38)	splice site	probably benign
R0537:Tenm2	UTSW	11	36,163,730 (GRCm38)	missense	probably damaging	1.00
R0599:Tenm2	UTSW	11	36,024,780 (GRCm38)	missense	possibly damaging	0.93
R0636:Tenm2	UTSW	11	36,943,976 (GRCm38)	missense	probably damaging	1.00
R0693:Tenm2	UTSW	11	36,024,809 (GRCm38)	missense	probably damaging	1.00
R0991:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R0992:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1167:Tenm2	UTSW	11	36,864,684 (GRCm38)	missense	probably benign	0.30
R1177:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1178:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1179:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1180:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1181:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1193:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1194:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1195:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1195:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1195:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1259:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1265:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1267:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1268:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1269:Tenm2	UTSW	11	36,008,358 (GRCm38)	missense	possibly damaging	0.64
R1270:Tenm2	UTSW	11	36,041,659 (GRCm38)	missense	probably damaging	1.00
R1272:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1273:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1311:Tenm2	UTSW	11	36,068,594 (GRCm38)	splice site	probably benign
R1374:Tenm2	UTSW	11	36,008,454 (GRCm38)	missense	probably benign	0.00
R1542:Tenm2	UTSW	11	36,300,220 (GRCm38)	missense	probably damaging	0.99
R1573:Tenm2	UTSW	11	36,047,069 (GRCm38)	missense	probably damaging	1.00
R1579:Tenm2	UTSW	11	36,106,783 (GRCm38)	missense	probably damaging	1.00
R1697:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1722:Tenm2	UTSW	11	36,008,103 (GRCm38)	missense	probably damaging	1.00
R1756:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1793:Tenm2	UTSW	11	36,023,382 (GRCm38)	missense	probably damaging	0.99
R1950:Tenm2	UTSW	11	36,063,177 (GRCm38)	missense	possibly damaging	0.94
R1954:Tenm2	UTSW	11	36,047,547 (GRCm38)	missense	possibly damaging	0.87
R2025:Tenm2	UTSW	11	36,047,264 (GRCm38)	nonsense	probably null
R2117:Tenm2	UTSW	11	36,024,854 (GRCm38)	missense	probably damaging	1.00
R2244:Tenm2	UTSW	11	36,864,862 (GRCm38)	missense	probably damaging	0.98
R2298:Tenm2	UTSW	11	36,046,777 (GRCm38)	missense	possibly damaging	0.62
R2432:Tenm2	UTSW	11	36,027,191 (GRCm38)	missense	probably damaging	1.00
R3014:Tenm2	UTSW	11	36,023,973 (GRCm38)	missense	probably damaging	1.00
R3115:Tenm2	UTSW	11	36,023,366 (GRCm38)	missense	probably damaging	1.00
R3684:Tenm2	UTSW	11	36,051,817 (GRCm38)	missense	probably benign	0.00
R3685:Tenm2	UTSW	11	36,051,817 (GRCm38)	missense	probably benign	0.00
R3705:Tenm2	UTSW	11	36,068,326 (GRCm38)	missense	probably damaging	0.97
R3820:Tenm2	UTSW	11	36,024,320 (GRCm38)	missense	probably damaging	0.98
R3821:Tenm2	UTSW	11	36,024,320 (GRCm38)	missense	probably damaging	0.98
R3822:Tenm2	UTSW	11	36,024,320 (GRCm38)	missense	probably damaging	0.98
R3844:Tenm2	UTSW	11	36,047,538 (GRCm38)	missense	probably damaging	0.98
R3878:Tenm2	UTSW	11	36,139,574 (GRCm38)	critical splice donor site	probably null
R4019:Tenm2	UTSW	11	36,047,074 (GRCm38)	missense	probably benign	0.04
R4062:Tenm2	UTSW	11	36,008,655 (GRCm38)	missense	probably damaging	1.00
R4367:Tenm2	UTSW	11	36,027,398 (GRCm38)	missense	probably benign
R4395:Tenm2	UTSW	11	36,024,624 (GRCm38)	missense	probably benign	0.23
R4508:Tenm2	UTSW	11	36,008,345 (GRCm38)	missense	possibly damaging	0.82
R4534:Tenm2	UTSW	11	36,063,104 (GRCm38)	missense	possibly damaging	0.64
R4539:Tenm2	UTSW	11	36,046,780 (GRCm38)	missense	probably damaging	1.00
R4644:Tenm2	UTSW	11	36,047,136 (GRCm38)	missense	probably benign	0.00
R4661:Tenm2	UTSW	11	36,024,448 (GRCm38)	missense	probably damaging	0.99
R4669:Tenm2	UTSW	11	36,010,487 (GRCm38)	missense	probably damaging	1.00
R4687:Tenm2	UTSW	11	36,049,097 (GRCm38)	missense	probably benign
R4711:Tenm2	UTSW	11	36,300,212 (GRCm38)	missense	probably damaging	0.98
R4816:Tenm2	UTSW	11	36,027,290 (GRCm38)	missense	probably damaging	1.00
R4843:Tenm2	UTSW	11	36,024,020 (GRCm38)	missense	probably damaging	1.00
R4850:Tenm2	UTSW	11	36,023,488 (GRCm38)	nonsense	probably null
R4870:Tenm2	UTSW	11	36,078,569 (GRCm38)	missense	probably damaging	1.00
R5058:Tenm2	UTSW	11	36,207,080 (GRCm38)	missense	possibly damaging	0.80
R5071:Tenm2	UTSW	11	36,068,381 (GRCm38)	missense	probably damaging	0.99
R5073:Tenm2	UTSW	11	36,068,381 (GRCm38)	missense	probably damaging	0.99
R5074:Tenm2	UTSW	11	36,068,381 (GRCm38)	missense	probably damaging	0.99
R5081:Tenm2	UTSW	11	36,024,633 (GRCm38)	missense	possibly damaging	0.95
R5093:Tenm2	UTSW	11	36,944,162 (GRCm38)	missense	probably damaging	1.00
R5170:Tenm2	UTSW	11	36,024,806 (GRCm38)	missense	probably damaging	0.98
R5253:Tenm2	UTSW	11	36,047,201 (GRCm38)	nonsense	probably null
R5343:Tenm2	UTSW	11	36,069,503 (GRCm38)	missense	probably benign	0.00
R5493:Tenm2	UTSW	11	36,864,676 (GRCm38)	missense	probably benign	0.01
R5600:Tenm2	UTSW	11	36,163,714 (GRCm38)	splice site	probably null
R5677:Tenm2	UTSW	11	36,141,683 (GRCm38)	missense	probably damaging	0.98
R5703:Tenm2	UTSW	11	36,023,799 (GRCm38)	missense	probably benign	0.34
R5707:Tenm2	UTSW	11	36,047,182 (GRCm38)	missense	possibly damaging	0.79
R6026:Tenm2	UTSW	11	36,072,729 (GRCm38)	critical splice donor site	probably null
R6063:Tenm2	UTSW	11	36,163,717 (GRCm38)	critical splice donor site	probably null
R6086:Tenm2	UTSW	11	36,008,646 (GRCm38)	missense	possibly damaging	0.64
R6151:Tenm2	UTSW	11	36,008,783 (GRCm38)	missense	probably damaging	1.00
R6169:Tenm2	UTSW	11	36,139,690 (GRCm38)	missense	probably damaging	0.99
R6193:Tenm2	UTSW	11	36,046,794 (GRCm38)	missense	probably damaging	1.00
R6405:Tenm2	UTSW	11	36,864,859 (GRCm38)	missense	probably benign	0.44
R6477:Tenm2	UTSW	11	36,010,507 (GRCm38)	critical splice acceptor site	probably null
R6607:Tenm2	UTSW	11	36,063,775 (GRCm38)	critical splice donor site	probably null
R6668:Tenm2	UTSW	11	36,046,765 (GRCm38)	critical splice donor site	probably null
R6825:Tenm2	UTSW	11	36,046,884 (GRCm38)	missense	probably benign	0.02
R6885:Tenm2	UTSW	11	36,023,580 (GRCm38)	missense	possibly damaging	0.95
R7017:Tenm2	UTSW	11	36,171,409 (GRCm38)	missense	probably damaging	0.98
R7115:Tenm2	UTSW	11	36,163,817 (GRCm38)	missense	probably damaging	0.99
R7153:Tenm2	UTSW	11	36,024,182 (GRCm38)	missense	probably damaging	0.98
R7173:Tenm2	UTSW	11	36,041,551 (GRCm38)	missense	probably damaging	0.99
R7199:Tenm2	UTSW	11	36,171,436 (GRCm38)	missense	probably damaging	1.00
R7205:Tenm2	UTSW	11	36,049,129 (GRCm38)	missense	probably damaging	0.99
R7250:Tenm2	UTSW	11	36,072,798 (GRCm38)	missense	probably damaging	1.00
R7290:Tenm2	UTSW	11	36,023,471 (GRCm38)	missense	probably damaging	1.00
R7366:Tenm2	UTSW	11	36,069,414 (GRCm38)	missense	probably benign	0.09
R7432:Tenm2	UTSW	11	36,864,941 (GRCm38)	missense	probably benign
R7504:Tenm2	UTSW	11	36,139,743 (GRCm38)	missense	probably damaging	1.00
R7513:Tenm2	UTSW	11	36,051,900 (GRCm38)	missense	probably benign	0.34
R7523:Tenm2	UTSW	11	36,078,581 (GRCm38)	splice site	probably null
R7527:Tenm2	UTSW	11	36,206,976 (GRCm38)	missense	probably damaging	1.00
R7648:Tenm2	UTSW	11	36,106,736 (GRCm38)	missense	probably damaging	1.00
R7653:Tenm2	UTSW	11	36,047,347 (GRCm38)	missense	probably benign	0.09
R7717:Tenm2	UTSW	11	36,864,935 (GRCm38)	missense	probably damaging	0.97
R7739:Tenm2	UTSW	11	36,069,561 (GRCm38)	missense	possibly damaging	0.50
R7762:Tenm2	UTSW	11	36,023,306 (GRCm38)	missense	possibly damaging	0.74
R7786:Tenm2	UTSW	11	36,010,449 (GRCm38)	missense	probably damaging	0.99
R7803:Tenm2	UTSW	11	36,047,116 (GRCm38)	missense	probably damaging	0.98
R7838:Tenm2	UTSW	11	36,106,799 (GRCm38)	missense	probably benign	0.02
R8073:Tenm2	UTSW	11	36,139,644 (GRCm38)	missense	possibly damaging	0.56
R8076:Tenm2	UTSW	11	36,027,221 (GRCm38)	missense	probably benign	0.23
R8109:Tenm2	UTSW	11	36,008,310 (GRCm38)	missense	probably benign
R8306:Tenm2	UTSW	11	36,069,369 (GRCm38)	missense	possibly damaging	0.52
R8352:Tenm2	UTSW	11	36,023,601 (GRCm38)	missense	probably damaging	0.98
R8452:Tenm2	UTSW	11	36,023,601 (GRCm38)	missense	probably damaging	0.98
R8864:Tenm2	UTSW	11	36,027,195 (GRCm38)	missense	possibly damaging	0.95
R8880:Tenm2	UTSW	11	36,051,961 (GRCm38)	missense	probably damaging	0.99
R8943:Tenm2	UTSW	11	36,944,034 (GRCm38)	missense	probably damaging	0.98
R8969:Tenm2	UTSW	11	36,051,861 (GRCm38)	missense	probably damaging	0.99
R9168:Tenm2	UTSW	11	36,039,895 (GRCm38)	missense	probably damaging	1.00
R9279:Tenm2	UTSW	11	36,068,476 (GRCm38)	missense	probably benign	0.00
R9294:Tenm2	UTSW	11	36,024,500 (GRCm38)	missense	probably damaging	0.98
R9320:Tenm2	UTSW	11	36,023,647 (GRCm38)	missense	probably damaging	0.99
R9373:Tenm2	UTSW	11	36,039,886 (GRCm38)	missense	probably damaging	1.00
R9408:Tenm2	UTSW	11	36,069,419 (GRCm38)	missense	probably damaging	1.00
R9410:Tenm2	UTSW	11	36,141,569 (GRCm38)	missense	probably damaging	0.99
R9454:Tenm2	UTSW	11	36,221,459 (GRCm38)	missense	probably benign
R9489:Tenm2	UTSW	11	36,943,964 (GRCm38)	missense	probably damaging	0.99
R9711:Tenm2	UTSW	11	36,024,514 (GRCm38)	missense	probably damaging	0.99
RF021:Tenm2	UTSW	11	36,024,203 (GRCm38)	missense	possibly damaging	0.95
X0018:Tenm2	UTSW	11	36,024,200 (GRCm38)	missense	probably damaging	1.00
X0063:Tenm2	UTSW	11	36,024,730 (GRCm38)	missense	probably benign
Z1088:Tenm2	UTSW	11	36,273,267 (GRCm38)	missense	probably damaging	1.00
Z1177:Tenm2	UTSW	11	36,300,335 (GRCm38)	missense	probably damaging	0.98
Z1177:Tenm2	UTSW	11	36,008,234 (GRCm38)	missense	possibly damaging	0.95
Z1177:Tenm2	UTSW	11	36,385,130 (GRCm38)	missense	probably benign	0.01

Predicted Primers

PCR Primer
(F):5'- ACTTGTAGAACACCTGGCGC -3'
(R):5'- CACACAGTCAAGGATTTATACGG -3'

Sequencing Primer
(F):5'- GCCCAGTGCCCAAGAAAGATG -3'
(R):5'- AGGCTACATGGTGTATAACTCTGTC -3'

Posted On

2019-12-20