|Institutional Source||Beutler Lab|
|Gene Name||ribosomal protein S26|
|Essential gene?||Not available|
|Stock #||R7835 (G1)|
|Chromosomal Location||128624534-128626747 bp(-) (GRCm38)|
|Type of Mutation||missense|
|DNA Base Change (assembly)||C to T at 128626126 bp (GRCm38)|
|Amino Acid Change||Valine to Isoleucine at position 40 (V40I)|
|Ref Sequence||ENSEMBL: ENSMUSP00000026420 (fasta)|
|Gene Model||predicted gene model for transcript(s): [ENSMUST00000026420] [ENSMUST00000133342]|
AA Change: V40I
PolyPhen 2 Score 0.023 (Sensitivity: 0.95; Specificity: 0.81)
AA Change: V40I
|Coding Region Coverage||
|Validation Efficiency||98% (48/49)|
|MGI Phenotype||FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S26E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]|
|Allele List at MGI|
|Other mutations in this stock||
|Other mutations in Rps26||
(F):5'- ACCATGCATGAGCCTCAATCTC -3'
(R):5'- AGGAAGGGCTGAATTCTCGC -3'
(F):5'- GTTAAAACCCCATCATTAGGCCTG -3'
(R):5'- GCCCCCTTTCCAATAGCG -3'