Mutagenetix > Incidental Mutation

Incidental Mutation 'R7850:Igsf10'

606872

Institutional Source

Beutler Lab

Gene Symbol

Igsf10

Ensembl Gene

ENSMUSG00000036334

Gene Name

immunoglobulin superfamily, member 10

Synonyms

6530405F15Rik, CMF608, Adlican2

MMRRC Submission

045903-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.194) question?

Stock #

R7850 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

59224156-59251815 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 59227053 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Leucine to Isoleucine at position 2207 (L2207I)

Ref Sequence

ENSEMBL: ENSMUSP00000037246 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000039419] [ENSMUST00000040325] [ENSMUST00000164225] [ENSMUST00000193455] [ENSMUST00000194546] [ENSMUST00000199659]

AlphaFold

Q3V1M1

Predicted Effect

probably benign
Transcript: ENSMUST00000039419
AA Change: L2207I

PolyPhen 2 Score 0.334 (Sensitivity: 0.90; Specificity: 0.89)

SMART Domains

Protein: ENSMUSP00000037246
Gene: ENSMUSG00000036334
AA Change: L2207I

Domain	Start	End	E-Value	Type
signal peptide	1	25	N/A	INTRINSIC
LRRNT	28	61	3.24e-4	SMART
LRR	57	79	9.24e1	SMART
LRR	80	103	2.02e-1	SMART
LRR	104	127	7.16e0	SMART
LRR_TYP	128	151	1.2e-3	SMART
LRR	152	175	1.25e-1	SMART
LRR	188	207	2.33e2	SMART
LRRCT	219	280	4.19e-4	SMART
IGc2	488	558	2.34e-4	SMART
IGc2	586	652	7.88e-11	SMART
low complexity region	917	930	N/A	INTRINSIC
low complexity region	1175	1185	N/A	INTRINSIC
low complexity region	1245	1263	N/A	INTRINSIC
low complexity region	1311	1321	N/A	INTRINSIC
low complexity region	1449	1465	N/A	INTRINSIC
IGc2	1632	1701	7.69e-14	SMART
IGc2	1729	1798	5.07e-14	SMART
IGc2	1826	1895	2.19e-9	SMART
IGc2	1925	1994	4.59e-12	SMART
IGc2	2022	2097	1.33e-8	SMART
IGc2	2125	2191	2.96e-15	SMART
IGc2	2223	2291	2.03e-4	SMART
IGc2	2321	2389	9.99e-13	SMART
IGc2	2416	2484	3.03e-12	SMART
IGc2	2512	2583	7.76e-10	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000040325

SMART Domains

Protein: ENSMUSP00000042269
Gene: ENSMUSG00000056476

Domain	Start	End	E-Value	Type
Med12	101	161	1.71e-24	SMART
low complexity region	216	224	N/A	INTRINSIC
low complexity region	269	278	N/A	INTRINSIC
Pfam:Med12-LCEWAV	282	730	2.6e-207	PFAM
low complexity region	744	758	N/A	INTRINSIC
low complexity region	853	872	N/A	INTRINSIC
low complexity region	1455	1466	N/A	INTRINSIC
low complexity region	1728	1742	N/A	INTRINSIC
low complexity region	1769	1783	N/A	INTRINSIC
Pfam:Med12-PQL	1803	2029	2.3e-14	PFAM
low complexity region	2055	2076	N/A	INTRINSIC
low complexity region	2083	2101	N/A	INTRINSIC
low complexity region	2116	2136	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000164225

SMART Domains

Protein: ENSMUSP00000127038
Gene: ENSMUSG00000056476

Domain	Start	End	E-Value	Type
Med12	101	161	1.71e-24	SMART
low complexity region	216	224	N/A	INTRINSIC
low complexity region	269	278	N/A	INTRINSIC
Pfam:Med12-LCEWAV	283	765	5e-187	PFAM
low complexity region	779	793	N/A	INTRINSIC
low complexity region	888	907	N/A	INTRINSIC
low complexity region	1490	1501	N/A	INTRINSIC
low complexity region	1763	1777	N/A	INTRINSIC
low complexity region	1804	1818	N/A	INTRINSIC
Pfam:Med12-PQL	1840	2063	9.7e-66	PFAM
low complexity region	2090	2111	N/A	INTRINSIC
low complexity region	2118	2136	N/A	INTRINSIC
low complexity region	2151	2171	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000193455
AA Change: L2207I

PolyPhen 2 Score 0.334 (Sensitivity: 0.90; Specificity: 0.89)

SMART Domains

Protein: ENSMUSP00000141971
Gene: ENSMUSG00000036334
AA Change: L2207I

Domain	Start	End	E-Value	Type
signal peptide	1	25	N/A	INTRINSIC
LRRNT	28	61	3.24e-4	SMART
LRR	57	79	9.24e1	SMART
LRR	80	103	2.02e-1	SMART
LRR	104	127	7.16e0	SMART
LRR_TYP	128	151	1.2e-3	SMART
LRR	152	175	1.25e-1	SMART
LRR	188	207	2.33e2	SMART
LRRCT	219	280	4.19e-4	SMART
IGc2	488	558	2.34e-4	SMART
IGc2	586	652	7.88e-11	SMART
low complexity region	917	930	N/A	INTRINSIC
low complexity region	1175	1185	N/A	INTRINSIC
low complexity region	1245	1263	N/A	INTRINSIC
low complexity region	1311	1321	N/A	INTRINSIC
low complexity region	1449	1465	N/A	INTRINSIC
IGc2	1632	1701	7.69e-14	SMART
IGc2	1729	1798	5.07e-14	SMART
IGc2	1826	1895	2.19e-9	SMART
IGc2	1925	1994	4.59e-12	SMART
IGc2	2022	2097	1.33e-8	SMART
IGc2	2125	2191	2.96e-15	SMART
IGc2	2223	2291	2.03e-4	SMART
IGc2	2321	2389	9.99e-13	SMART
IGc2	2416	2484	3.03e-12	SMART
IGc2	2512	2583	7.76e-10	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000194546
AA Change: L2207I

PolyPhen 2 Score 0.334 (Sensitivity: 0.90; Specificity: 0.89)

SMART Domains

Protein: ENSMUSP00000141391
Gene: ENSMUSG00000036334
AA Change: L2207I

Domain	Start	End	E-Value	Type
signal peptide	1	25	N/A	INTRINSIC
LRRNT	28	61	3.24e-4	SMART
LRR	57	79	9.24e1	SMART
LRR	80	103	2.02e-1	SMART
LRR	104	127	7.16e0	SMART
LRR_TYP	128	151	1.2e-3	SMART
LRR	152	175	1.25e-1	SMART
LRR	188	207	2.33e2	SMART
LRRCT	219	280	4.19e-4	SMART
IGc2	488	558	2.34e-4	SMART
IGc2	586	652	7.88e-11	SMART
low complexity region	917	930	N/A	INTRINSIC
low complexity region	1175	1185	N/A	INTRINSIC
low complexity region	1245	1263	N/A	INTRINSIC
low complexity region	1311	1321	N/A	INTRINSIC
low complexity region	1449	1465	N/A	INTRINSIC
IGc2	1632	1701	7.69e-14	SMART
IGc2	1729	1798	5.07e-14	SMART
IGc2	1826	1895	2.19e-9	SMART
IGc2	1925	1994	4.59e-12	SMART
IGc2	2022	2097	1.33e-8	SMART
IGc2	2125	2191	2.96e-15	SMART
IGc2	2223	2291	2.03e-4	SMART
IGc2	2321	2389	9.99e-13	SMART
IGc2	2416	2484	3.03e-12	SMART
IGc2	2512	2583	7.76e-10	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000197374

Predicted Effect

probably benign
Transcript: ENSMUST00000199659

SMART Domains

Protein: ENSMUSP00000142903
Gene: ENSMUSG00000056476

Domain	Start	End	E-Value	Type
Med12	101	161	1.71e-24	SMART
low complexity region	216	224	N/A	INTRINSIC
low complexity region	269	278	N/A	INTRINSIC
Pfam:Med12-LCEWAV	282	765	5.5e-209	PFAM
low complexity region	779	793	N/A	INTRINSIC
low complexity region	888	907	N/A	INTRINSIC
low complexity region	1490	1501	N/A	INTRINSIC
low complexity region	1761	1775	N/A	INTRINSIC
low complexity region	1802	1816	N/A	INTRINSIC
Pfam:Med12-PQL	1836	2062	1.7e-15	PFAM
low complexity region	2088	2130	N/A	INTRINSIC
low complexity region	2144	2164	N/A	INTRINSIC

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.7%
20x: 98.9%

Validation Efficiency

100% (43/43)

Allele List at MGI

All alleles(2) : Targeted, other(2)

Other mutations in this stock

Total: 46 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
A630089N07Rik	A	T	16: 97,869,328 (GRCm39)	D2E	probably damaging	Het
Abhd16b	G	A	2: 181,135,518 (GRCm39)	R140H	not run	Het
Acad11	G	T	9: 103,991,728 (GRCm39)	G588C	probably damaging	Het
Baz2b	C	A	2: 59,767,060 (GRCm39)	E107D	probably damaging	Het
Bcas1	A	G	2: 170,190,023 (GRCm39)	S625P	probably damaging	Het
Bdp1	T	A	13: 100,228,832 (GRCm39)	L265F	probably damaging	Het
Cacna1s	A	G	1: 135,998,786 (GRCm39)	Y227C	probably damaging	Het
Cacna2d2	G	A	9: 107,402,575 (GRCm39)	A848T	probably benign	Het
Cep135	T	C	5: 76,739,720 (GRCm39)		probably null	Het
Cyp2b9	G	T	7: 25,886,111 (GRCm39)	E93*	probably null	Het
Dcp2	C	A	18: 44,533,415 (GRCm39)	S122*	probably null	Het
Ecel1	A	G	1: 87,079,745 (GRCm39)	L456P	probably damaging	Het
Entpd8	T	C	2: 24,975,028 (GRCm39)	M453T	probably damaging	Het
Gcc2	T	A	10: 58,114,703 (GRCm39)	V1084D	probably damaging	Het
Grem1	A	G	2: 113,580,178 (GRCm39)	C108R	probably damaging	Het
Gtf2ird1	T	C	5: 134,392,069 (GRCm39)	E880G	probably benign	Het
Hacd2	T	A	16: 34,922,477 (GRCm39)	M222K	probably damaging	Het
Htr1b	G	T	9: 81,514,652 (GRCm39)		probably null	Het
Htt	T	G	5: 35,009,631 (GRCm39)		probably null	Het
Ifnab	T	G	4: 88,609,133 (GRCm39)	D111A	probably benign	Het
Itln1	T	C	1: 171,358,166 (GRCm39)	Y194C	probably damaging	Het
Kmt5b	T	A	19: 3,865,043 (GRCm39)	D702E	probably damaging	Het
Knop1	T	C	7: 118,449,860 (GRCm39)	E382G	unknown	Het
Lrit3	A	C	3: 129,594,452 (GRCm39)	L42V	probably damaging	Het
Mug2	A	G	6: 122,052,170 (GRCm39)	E976G	probably damaging	Het
Or5an10	T	C	19: 12,275,996 (GRCm39)	M167V	probably benign	Het
Or8g28	A	T	9: 39,169,518 (GRCm39)	I150N	possibly damaging	Het
Or8s8	G	A	15: 98,354,949 (GRCm39)	G253R	probably damaging	Het
Papln	A	T	12: 83,827,436 (GRCm39)	E758V	probably damaging	Het
Pcnx3	A	C	19: 5,728,960 (GRCm39)	F967V	possibly damaging	Het
Pcnx4	G	T	12: 72,602,842 (GRCm39)	C368F	probably benign	Het
Pi15	T	A	1: 17,673,105 (GRCm39)	Y101*	probably null	Het
Ppp1r9a	G	A	6: 4,905,894 (GRCm39)	V150M	possibly damaging	Het
Prrt4	A	T	6: 29,176,900 (GRCm39)		probably null	Het
Ptgdr	A	G	14: 45,090,828 (GRCm39)	V310A	probably benign	Het
Ric1	G	A	19: 29,572,293 (GRCm39)	S696N	probably benign	Het
Setx	T	A	2: 29,037,430 (GRCm39)	V1305D	probably damaging	Het
Slk	G	A	19: 47,610,796 (GRCm39)	R822H	probably damaging	Het
Tas2r135	T	A	6: 42,383,072 (GRCm39)	F204I	probably benign	Het
Tcaf3	A	T	6: 42,571,140 (GRCm39)		probably null	Het
Tmtc2	A	G	10: 105,409,568 (GRCm39)	Y15H	probably benign	Het
Treml2	T	C	17: 48,615,168 (GRCm39)	S218P	probably benign	Het
Tubb2a	T	C	13: 34,258,554 (GRCm39)	E412G	probably damaging	Het
Usp48	T	G	4: 137,333,060 (GRCm39)		probably null	Het
Vmn2r25	A	T	6: 123,805,431 (GRCm39)	N475K	probably damaging	Het
Zscan4-ps1	G	A	7: 10,799,735 (GRCm39)	H385Y	probably benign	Het

Other mutations in Igsf10

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00773:Igsf10	APN	3	59,238,960 (GRCm39)	missense	probably benign	0.03
IGL00790:Igsf10	APN	3	59,226,938 (GRCm39)	missense	probably damaging	1.00
IGL00916:Igsf10	APN	3	59,238,548 (GRCm39)	missense	probably damaging	0.97
IGL00928:Igsf10	APN	3	59,238,018 (GRCm39)	missense	probably benign	0.00
IGL01066:Igsf10	APN	3	59,235,203 (GRCm39)	critical splice donor site	probably null
IGL01107:Igsf10	APN	3	59,238,945 (GRCm39)	missense	probably damaging	1.00
IGL01420:Igsf10	APN	3	59,227,071 (GRCm39)	missense	probably benign	0.02
IGL01533:Igsf10	APN	3	59,226,651 (GRCm39)	missense	probably damaging	0.98
IGL01537:Igsf10	APN	3	59,237,452 (GRCm39)	missense	probably benign	0.00
IGL01676:Igsf10	APN	3	59,236,756 (GRCm39)	missense	probably benign	0.17
IGL01676:Igsf10	APN	3	59,233,432 (GRCm39)	missense	probably benign	0.06
IGL01960:Igsf10	APN	3	59,226,158 (GRCm39)	missense	probably benign	0.00
IGL02123:Igsf10	APN	3	59,226,081 (GRCm39)	missense	probably damaging	0.97
IGL02198:Igsf10	APN	3	59,233,399 (GRCm39)	missense	possibly damaging	0.95
IGL02268:Igsf10	APN	3	59,238,573 (GRCm39)	nonsense	probably null
IGL02313:Igsf10	APN	3	59,238,111 (GRCm39)	missense	probably benign	0.01
IGL02368:Igsf10	APN	3	59,235,652 (GRCm39)	missense	probably benign
IGL02494:Igsf10	APN	3	59,235,427 (GRCm39)	missense	probably damaging	0.98
IGL02549:Igsf10	APN	3	59,236,662 (GRCm39)	missense	probably benign	0.03
IGL02616:Igsf10	APN	3	59,226,027 (GRCm39)	missense	probably benign	0.06
IGL02957:Igsf10	APN	3	59,238,285 (GRCm39)	missense	probably damaging	1.00
IGL03067:Igsf10	APN	3	59,226,339 (GRCm39)	missense	probably benign	0.25
IGL03104:Igsf10	APN	3	59,226,905 (GRCm39)	missense	probably damaging	1.00
IGL03124:Igsf10	APN	3	59,227,086 (GRCm39)	missense	probably benign	0.01
IGL03212:Igsf10	APN	3	59,235,586 (GRCm39)	missense	probably benign	0.09
IGL03347:Igsf10	APN	3	59,239,321 (GRCm39)	missense	possibly damaging	0.94
IGL03357:Igsf10	APN	3	59,243,632 (GRCm39)	missense	probably benign	0.35
F6893:Igsf10	UTSW	3	59,238,481 (GRCm39)	missense	probably damaging	1.00
FR4449:Igsf10	UTSW	3	59,226,531 (GRCm39)	missense	probably damaging	1.00
PIT1430001:Igsf10	UTSW	3	59,235,579 (GRCm39)	missense	probably benign	0.06
PIT4402001:Igsf10	UTSW	3	59,233,000 (GRCm39)	missense	probably benign	0.00
PIT4810001:Igsf10	UTSW	3	59,225,903 (GRCm39)	missense	probably damaging	1.00
R0068:Igsf10	UTSW	3	59,238,045 (GRCm39)	missense	probably damaging	0.98
R0095:Igsf10	UTSW	3	59,238,617 (GRCm39)	nonsense	probably null
R0095:Igsf10	UTSW	3	59,238,617 (GRCm39)	nonsense	probably null
R0112:Igsf10	UTSW	3	59,233,429 (GRCm39)	missense	probably benign	0.00
R0141:Igsf10	UTSW	3	59,238,253 (GRCm39)	missense	probably damaging	1.00
R0538:Igsf10	UTSW	3	59,227,527 (GRCm39)	missense	probably damaging	0.99
R0551:Igsf10	UTSW	3	59,236,089 (GRCm39)	missense	probably benign	0.01
R0556:Igsf10	UTSW	3	59,236,296 (GRCm39)	missense	probably benign	0.02
R0582:Igsf10	UTSW	3	59,227,188 (GRCm39)	missense	probably benign	0.00
R0630:Igsf10	UTSW	3	59,233,483 (GRCm39)	missense	probably damaging	1.00
R0675:Igsf10	UTSW	3	59,236,015 (GRCm39)	missense	probably benign	0.14
R0948:Igsf10	UTSW	3	59,238,525 (GRCm39)	missense	probably damaging	1.00
R1252:Igsf10	UTSW	3	59,239,269 (GRCm39)	missense	probably benign	0.03
R1412:Igsf10	UTSW	3	59,235,196 (GRCm39)	splice site	probably benign
R1473:Igsf10	UTSW	3	59,226,188 (GRCm39)	missense	probably damaging	1.00
R1585:Igsf10	UTSW	3	59,237,838 (GRCm39)	missense	probably damaging	1.00
R1650:Igsf10	UTSW	3	59,233,583 (GRCm39)	missense	probably damaging	1.00
R1660:Igsf10	UTSW	3	59,238,706 (GRCm39)	missense	probably damaging	1.00
R1671:Igsf10	UTSW	3	59,235,921 (GRCm39)	nonsense	probably null
R1748:Igsf10	UTSW	3	59,226,514 (GRCm39)	missense	probably damaging	1.00
R1758:Igsf10	UTSW	3	59,236,617 (GRCm39)	missense	probably benign	0.09
R1856:Igsf10	UTSW	3	59,238,693 (GRCm39)	missense	possibly damaging	0.63
R1912:Igsf10	UTSW	3	59,236,993 (GRCm39)	missense	probably benign	0.40
R2148:Igsf10	UTSW	3	59,243,998 (GRCm39)	missense	possibly damaging	0.77
R2155:Igsf10	UTSW	3	59,239,101 (GRCm39)	missense	probably damaging	1.00
R2509:Igsf10	UTSW	3	59,239,287 (GRCm39)	missense	probably damaging	1.00
R2511:Igsf10	UTSW	3	59,239,287 (GRCm39)	missense	probably damaging	1.00
R2680:Igsf10	UTSW	3	59,232,875 (GRCm39)	missense	probably benign	0.14
R2913:Igsf10	UTSW	3	59,239,157 (GRCm39)	missense	possibly damaging	0.70
R2927:Igsf10	UTSW	3	59,236,848 (GRCm39)	missense	probably benign
R3547:Igsf10	UTSW	3	59,243,935 (GRCm39)	missense	probably damaging	1.00
R3547:Igsf10	UTSW	3	59,237,962 (GRCm39)	missense	probably benign	0.02
R3548:Igsf10	UTSW	3	59,243,935 (GRCm39)	missense	probably damaging	1.00
R3620:Igsf10	UTSW	3	59,243,752 (GRCm39)	missense	probably damaging	1.00
R3732:Igsf10	UTSW	3	59,233,135 (GRCm39)	missense	probably benign	0.29
R3743:Igsf10	UTSW	3	59,233,546 (GRCm39)	missense	possibly damaging	0.69
R3973:Igsf10	UTSW	3	59,239,345 (GRCm39)	missense	probably damaging	1.00
R4005:Igsf10	UTSW	3	59,235,981 (GRCm39)	missense	probably benign	0.00
R4184:Igsf10	UTSW	3	59,227,152 (GRCm39)	missense	probably damaging	1.00
R4302:Igsf10	UTSW	3	59,226,171 (GRCm39)	missense	probably damaging	1.00
R4404:Igsf10	UTSW	3	59,236,972 (GRCm39)	missense	probably benign	0.04
R4575:Igsf10	UTSW	3	59,237,521 (GRCm39)	missense	probably benign
R4676:Igsf10	UTSW	3	59,233,370 (GRCm39)	missense	probably benign	0.23
R4700:Igsf10	UTSW	3	59,227,751 (GRCm39)	missense	probably damaging	0.99
R4765:Igsf10	UTSW	3	59,237,126 (GRCm39)	missense	probably benign	0.01
R4986:Igsf10	UTSW	3	59,236,027 (GRCm39)	missense	probably benign	0.24
R5012:Igsf10	UTSW	3	59,226,143 (GRCm39)	missense	probably damaging	1.00
R5070:Igsf10	UTSW	3	59,235,714 (GRCm39)	missense	probably benign	0.02
R5083:Igsf10	UTSW	3	59,233,694 (GRCm39)	missense	probably damaging	1.00
R5336:Igsf10	UTSW	3	59,227,553 (GRCm39)	missense	probably damaging	1.00
R5462:Igsf10	UTSW	3	59,233,175 (GRCm39)	missense	probably damaging	1.00
R5648:Igsf10	UTSW	3	59,235,574 (GRCm39)	missense	probably benign	0.01
R5810:Igsf10	UTSW	3	59,226,492 (GRCm39)	missense	probably damaging	1.00
R5871:Igsf10	UTSW	3	59,237,832 (GRCm39)	missense	possibly damaging	0.83
R5880:Igsf10	UTSW	3	59,238,252 (GRCm39)	missense	probably damaging	1.00
R5935:Igsf10	UTSW	3	59,235,578 (GRCm39)	missense	probably benign	0.12
R5979:Igsf10	UTSW	3	59,243,894 (GRCm39)	missense	probably damaging	1.00
R6145:Igsf10	UTSW	3	59,239,077 (GRCm39)	missense	possibly damaging	0.83
R6222:Igsf10	UTSW	3	59,226,336 (GRCm39)	missense	possibly damaging	0.90
R6224:Igsf10	UTSW	3	59,232,931 (GRCm39)	missense	probably damaging	1.00
R6264:Igsf10	UTSW	3	59,235,928 (GRCm39)	missense	possibly damaging	0.88
R6283:Igsf10	UTSW	3	59,226,870 (GRCm39)	missense	probably damaging	1.00
R6336:Igsf10	UTSW	3	59,237,760 (GRCm39)	missense	probably benign	0.00
R6490:Igsf10	UTSW	3	59,236,992 (GRCm39)	missense	probably benign	0.06
R6785:Igsf10	UTSW	3	59,226,665 (GRCm39)	missense	probably damaging	1.00
R6873:Igsf10	UTSW	3	59,235,865 (GRCm39)	missense	probably benign
R6889:Igsf10	UTSW	3	59,239,354 (GRCm39)	missense	probably benign
R7024:Igsf10	UTSW	3	59,239,122 (GRCm39)	missense	probably benign	0.00
R7056:Igsf10	UTSW	3	59,238,501 (GRCm39)	missense	probably damaging	1.00
R7128:Igsf10	UTSW	3	59,236,326 (GRCm39)	missense	probably benign
R7251:Igsf10	UTSW	3	59,226,875 (GRCm39)	missense	probably damaging	1.00
R7313:Igsf10	UTSW	3	59,236,837 (GRCm39)	missense	probably benign	0.05
R7340:Igsf10	UTSW	3	59,233,189 (GRCm39)	missense	probably damaging	1.00
R7447:Igsf10	UTSW	3	59,239,222 (GRCm39)	missense	probably benign	0.39
R7506:Igsf10	UTSW	3	59,226,775 (GRCm39)	missense	probably damaging	1.00
R7678:Igsf10	UTSW	3	59,226,761 (GRCm39)	missense	possibly damaging	0.81
R7695:Igsf10	UTSW	3	59,233,612 (GRCm39)	missense	probably damaging	1.00
R7709:Igsf10	UTSW	3	59,238,964 (GRCm39)	missense	probably damaging	0.96
R7749:Igsf10	UTSW	3	59,236,549 (GRCm39)	missense	possibly damaging	0.88
R7808:Igsf10	UTSW	3	59,235,489 (GRCm39)	missense	probably benign	0.00
R7879:Igsf10	UTSW	3	59,238,145 (GRCm39)	missense	probably damaging	1.00
R7886:Igsf10	UTSW	3	59,235,748 (GRCm39)	missense	probably benign	0.01
R7891:Igsf10	UTSW	3	59,235,832 (GRCm39)	nonsense	probably null
R7946:Igsf10	UTSW	3	59,227,125 (GRCm39)	missense	possibly damaging	0.69
R7948:Igsf10	UTSW	3	59,239,279 (GRCm39)	missense	probably benign	0.02
R8004:Igsf10	UTSW	3	59,237,130 (GRCm39)	missense	probably benign	0.01
R8096:Igsf10	UTSW	3	59,236,380 (GRCm39)	missense	probably damaging	0.98
R8141:Igsf10	UTSW	3	59,237,949 (GRCm39)	missense	probably damaging	0.96
R8183:Igsf10	UTSW	3	59,238,036 (GRCm39)	missense	probably benign	0.04
R8203:Igsf10	UTSW	3	59,236,254 (GRCm39)	missense	probably benign	0.11
R8325:Igsf10	UTSW	3	59,225,954 (GRCm39)	missense	probably damaging	0.96
R8350:Igsf10	UTSW	3	59,238,949 (GRCm39)	missense	probably damaging	1.00
R8387:Igsf10	UTSW	3	59,236,564 (GRCm39)	missense	probably damaging	1.00
R8488:Igsf10	UTSW	3	59,227,431 (GRCm39)	missense	probably damaging	1.00
R8697:Igsf10	UTSW	3	59,226,308 (GRCm39)	missense	probably benign	0.02
R8786:Igsf10	UTSW	3	59,238,063 (GRCm39)	missense	probably benign	0.25
R8804:Igsf10	UTSW	3	59,243,876 (GRCm39)	missense	probably damaging	1.00
R8886:Igsf10	UTSW	3	59,237,410 (GRCm39)	missense	probably benign	0.00
R8902:Igsf10	UTSW	3	59,243,633 (GRCm39)	missense	probably benign	0.00
R8906:Igsf10	UTSW	3	59,233,739 (GRCm39)	missense	probably benign	0.01
R8917:Igsf10	UTSW	3	59,226,888 (GRCm39)	missense	possibly damaging	0.69
R9051:Igsf10	UTSW	3	59,236,668 (GRCm39)	missense	probably benign	0.00
R9178:Igsf10	UTSW	3	59,233,480 (GRCm39)	missense	possibly damaging	0.69
R9228:Igsf10	UTSW	3	59,243,843 (GRCm39)	missense	probably damaging	1.00
R9230:Igsf10	UTSW	3	59,243,843 (GRCm39)	missense	probably damaging	1.00
R9231:Igsf10	UTSW	3	59,243,843 (GRCm39)	missense	probably damaging	1.00
R9232:Igsf10	UTSW	3	59,243,843 (GRCm39)	missense	probably damaging	1.00
R9417:Igsf10	UTSW	3	59,236,526 (GRCm39)	missense	possibly damaging	0.94
R9609:Igsf10	UTSW	3	59,226,869 (GRCm39)	missense	probably damaging	1.00
R9631:Igsf10	UTSW	3	59,237,904 (GRCm39)	missense	probably damaging	1.00
R9689:Igsf10	UTSW	3	59,233,624 (GRCm39)	missense	probably damaging	1.00
R9762:Igsf10	UTSW	3	59,237,106 (GRCm39)	missense	probably damaging	1.00
R9770:Igsf10	UTSW	3	59,227,199 (GRCm39)	missense	probably benign	0.07
R9798:Igsf10	UTSW	3	59,239,126 (GRCm39)	missense	probably damaging	1.00
Z1088:Igsf10	UTSW	3	59,237,359 (GRCm39)	missense	possibly damaging	0.59
Z1177:Igsf10	UTSW	3	59,237,026 (GRCm39)	nonsense	probably null

Predicted Primers

PCR Primer
(F):5'- GCAGAATCAGAAAGCCTTATGTTC -3'
(R):5'- TGCTGCCTTCCAACAATGTC -3'

Sequencing Primer
(F):5'- CAAGGTTCCATTTTGATGCACG -3'
(R):5'- CATTTCATTCTCCAATGACAGGTTC -3'

Posted On

2019-12-20