Incidental Mutation 'R7861:Cux1'
| ID |
607503 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Cux1
|
| Ensembl Gene |
ENSMUSG00000029705 |
| Gene Name |
cut-like homeobox 1 |
| Synonyms |
Cux-1, Cutl1, CDP, Cux |
| MMRRC Submission |
045914-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.861)
|
| Stock # |
R7861 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
5 |
| Chromosomal Location |
136248135-136567490 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 136252604 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Glycine
at position 568
(E568G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000135054
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000175918]
[ENSMUST00000175998]
[ENSMUST00000176216]
[ENSMUST00000176745]
[ENSMUST00000177297]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000175918
|
| SMART Domains |
Protein: ENSMUSP00000135606
Gene: ENSMUSG00000029705
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
73 |
328 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000175998
AA Change: E362G
PolyPhen 2
Score 0.105 (Sensitivity: 0.93; Specificity: 0.86)
|
| SMART Domains |
Protein: ENSMUSP00000135816
Gene: ENSMUSG00000029705
AA Change: E362G
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
1 |
39 |
N/A |
INTRINSIC |
|
low complexity region
|
52 |
64 |
N/A |
INTRINSIC |
|
coiled coil region
|
76 |
148 |
N/A |
INTRINSIC |
|
Pfam:CASP_C
|
204 |
430 |
8.6e-72 |
PFAM |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000176216
AA Change: E568G
PolyPhen 2
Score 0.584 (Sensitivity: 0.88; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000135054
Gene: ENSMUSG00000029705
AA Change: E568G
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
16 |
45 |
N/A |
INTRINSIC |
|
coiled coil region
|
110 |
365 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
369 |
390 |
9.35e-5 |
PROSPERO |
|
Pfam:CASP_C
|
421 |
647 |
1.2e-71 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000176745
AA Change: E566G
PolyPhen 2
Score 0.136 (Sensitivity: 0.92; Specificity: 0.86)
|
| SMART Domains |
Protein: ENSMUSP00000135512
Gene: ENSMUSG00000029705
AA Change: E566G
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
16 |
45 |
N/A |
INTRINSIC |
|
coiled coil region
|
110 |
363 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
367 |
388 |
8.95e-5 |
PROSPERO |
|
Pfam:CASP_C
|
419 |
645 |
1.2e-71 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000177297
|
| SMART Domains |
Protein: ENSMUSP00000134819
Gene: ENSMUSG00000029705
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
16 |
45 |
N/A |
INTRINSIC |
|
coiled coil region
|
110 |
365 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
369 |
390 |
8.99e-6 |
PROSPERO |
|
Pfam:CASP_C
|
422 |
527 |
1.8e-17 |
PFAM |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.2%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Homozygotes for a targeted null mutation exhibit delayed lung development and neonatal mortality. Survivors show growth retardation and hair defects. Homozygotes for a partially deleted protein have curly hair, and females tend to lose their litters. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 81 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700016H13Rik |
T |
A |
5: 103,649,494 (GRCm38) |
I50F |
possibly damaging |
Het |
| Abcc3 |
T |
C |
11: 94,357,249 (GRCm38) |
D1175G |
probably null |
Het |
| Accs |
C |
A |
2: 93,835,732 (GRCm38) |
*503L |
probably null |
Het |
| Adgra2 |
A |
G |
8: 27,114,457 (GRCm38) |
E520G |
probably damaging |
Het |
| Aldh7a1 |
C |
A |
18: 56,548,453 (GRCm38) |
C215F |
probably benign |
Het |
| Apbb1ip |
A |
C |
2: 22,816,978 (GRCm38) |
D9A |
unknown |
Het |
| Atad2 |
G |
A |
15: 58,125,780 (GRCm38) |
A228V |
probably benign |
Het |
| Atp10a |
T |
C |
7: 58,788,359 (GRCm38) |
S430P |
probably damaging |
Het |
| Atp1a3 |
T |
C |
7: 25,001,148 (GRCm38) |
D6G |
unknown |
Het |
| Brca1 |
A |
T |
11: 101,526,422 (GRCm38) |
N295K |
possibly damaging |
Het |
| Caly |
C |
A |
7: 140,081,388 (GRCm38) |
|
probably benign |
Het |
| Ces1h |
A |
G |
8: 93,357,425 (GRCm38) |
Y386H |
unknown |
Het |
| Col14a1 |
A |
G |
15: 55,444,616 (GRCm38) |
D1044G |
unknown |
Het |
| Csf2rb |
A |
G |
15: 78,349,157 (GRCm38) |
D888G |
probably damaging |
Het |
| Dhrs7b |
T |
A |
11: 60,855,742 (GRCm38) |
L219Q |
probably damaging |
Het |
| Dlg5 |
G |
A |
14: 24,245,212 (GRCm38) |
P80L |
probably damaging |
Het |
| Dnah14 |
C |
T |
1: 181,616,759 (GRCm38) |
P545S |
probably damaging |
Het |
| Dnajc24 |
A |
T |
2: 106,002,035 (GRCm38) |
M1K |
probably null |
Het |
| Dusp12 |
C |
T |
1: 170,874,526 (GRCm38) |
W301* |
probably null |
Het |
| Dyrk1a |
G |
T |
16: 94,691,716 (GRCm38) |
G603* |
probably null |
Het |
| Eif4g1 |
T |
A |
16: 20,679,702 (GRCm38) |
V403E |
probably benign |
Het |
| Epn3 |
T |
C |
11: 94,496,274 (GRCm38) |
E90G |
probably damaging |
Het |
| Etl4 |
A |
G |
2: 20,805,910 (GRCm38) |
S1303G |
probably benign |
Het |
| Evpl |
A |
T |
11: 116,228,069 (GRCm38) |
Y627N |
probably damaging |
Het |
| Fbxw25 |
A |
T |
9: 109,664,557 (GRCm38) |
L22* |
probably null |
Het |
| Fcamr |
T |
A |
1: 130,814,638 (GRCm38) |
N587K |
probably benign |
Het |
| Fgd6 |
A |
G |
10: 94,103,331 (GRCm38) |
N946S |
probably benign |
Het |
| Fndc3b |
A |
T |
3: 27,468,999 (GRCm38) |
I477N |
possibly damaging |
Het |
| Grifin |
C |
T |
5: 140,564,525 (GRCm38) |
A54T |
probably benign |
Het |
| Gtf2b |
A |
G |
3: 142,781,344 (GRCm38) |
I180M |
probably damaging |
Het |
| Invs |
A |
T |
4: 48,397,559 (GRCm38) |
D378V |
possibly damaging |
Het |
| Itgb6 |
T |
C |
2: 60,628,444 (GRCm38) |
E378G |
probably damaging |
Het |
| Khdc1a |
T |
C |
1: 21,350,399 (GRCm38) |
I81T |
possibly damaging |
Het |
| Kif20b |
T |
A |
19: 34,939,922 (GRCm38) |
D617E |
probably damaging |
Het |
| Kifc3 |
T |
A |
8: 95,107,537 (GRCm38) |
|
probably null |
Het |
| Kirrel3 |
C |
T |
9: 35,020,123 (GRCm38) |
H403Y |
possibly damaging |
Het |
| Klf15 |
G |
A |
6: 90,466,838 (GRCm38) |
V132I |
probably benign |
Het |
| Kmt2a |
A |
G |
9: 44,818,734 (GRCm38) |
S3429P |
unknown |
Het |
| Lama1 |
T |
G |
17: 67,809,221 (GRCm38) |
L2361R |
|
Het |
| Lrp1b |
T |
C |
2: 40,697,558 (GRCm38) |
D3895G |
|
Het |
| Mcoln3 |
A |
C |
3: 146,124,791 (GRCm38) |
E92A |
possibly damaging |
Het |
| Myo3b |
T |
C |
2: 70,108,688 (GRCm38) |
M135T |
probably damaging |
Het |
| Mysm1 |
A |
G |
4: 94,946,967 (GRCm38) |
*820Q |
probably null |
Het |
| Ncoa7 |
A |
G |
10: 30,691,060 (GRCm38) |
S541P |
probably benign |
Het |
| Nup54 |
T |
C |
5: 92,431,093 (GRCm38) |
T33A |
unknown |
Het |
| Or10al2 |
C |
A |
17: 37,672,517 (GRCm38) |
Q165K |
possibly damaging |
Het |
| Or13a17 |
T |
G |
7: 140,691,571 (GRCm38) |
I222S |
probably damaging |
Het |
| Or1s2 |
T |
C |
19: 13,781,446 (GRCm38) |
V276A |
possibly damaging |
Het |
| Or4k42 |
T |
A |
2: 111,490,024 (GRCm38) |
I45F |
probably damaging |
Het |
| Or51a5 |
T |
A |
7: 103,122,692 (GRCm38) |
I27F |
probably benign |
Het |
| Otud6b |
A |
G |
4: 14,826,414 (GRCm38) |
C18R |
probably benign |
Het |
| Pde4d |
A |
G |
13: 109,935,324 (GRCm38) |
E284G |
probably damaging |
Het |
| Peg10 |
CATCAGGATCCCCATCAGGATGCACATCAGGATCCACATCAGGATGCACATCAGGATC |
CATC |
6: 4,756,431 (GRCm38) |
|
probably benign |
Het |
| Pidd1 |
C |
A |
7: 141,440,142 (GRCm38) |
W598L |
probably damaging |
Het |
| Pira2 |
A |
T |
7: 3,844,544 (GRCm38) |
C49S |
probably damaging |
Het |
| Pramel11 |
T |
C |
4: 143,897,718 (GRCm38) |
M70V |
possibly damaging |
Het |
| Prdx1 |
T |
G |
4: 116,693,738 (GRCm38) |
D135E |
probably benign |
Het |
| Rab15 |
T |
A |
12: 76,803,129 (GRCm38) |
Y88F |
probably damaging |
Het |
| Rem2 |
C |
A |
14: 54,477,799 (GRCm38) |
H144Q |
probably damaging |
Het |
| Sel1l3 |
T |
C |
5: 53,144,064 (GRCm38) |
D737G |
probably damaging |
Het |
| Srd5a3 |
C |
T |
5: 76,147,819 (GRCm38) |
Q119* |
probably null |
Het |
| Suclg2 |
G |
T |
6: 95,594,722 (GRCm38) |
Q120K |
probably benign |
Het |
| Tacc2 |
T |
A |
7: 130,625,431 (GRCm38) |
M1282K |
probably benign |
Het |
| Tbc1d5 |
T |
A |
17: 50,756,692 (GRCm38) |
Q620L |
probably damaging |
Het |
| Tdrd3 |
G |
T |
14: 87,472,154 (GRCm38) |
A91S |
probably damaging |
Het |
| Thsd7b |
T |
A |
1: 130,159,698 (GRCm38) |
F1184Y |
probably benign |
Het |
| Trim28 |
T |
A |
7: 13,028,412 (GRCm38) |
V321E |
possibly damaging |
Het |
| Trim5 |
C |
A |
7: 104,266,468 (GRCm38) |
|
probably null |
Het |
| Ugt2b37 |
A |
T |
5: 87,242,440 (GRCm38) |
Y382* |
probably null |
Het |
| Usp40 |
C |
T |
1: 87,982,130 (GRCm38) |
G534D |
probably damaging |
Het |
| Usp53 |
A |
T |
3: 122,934,463 (GRCm38) |
H823Q |
probably benign |
Het |
| Vmn2r12 |
T |
A |
5: 109,087,963 (GRCm38) |
M508L |
probably benign |
Het |
| Vmn2r56 |
T |
A |
7: 12,715,424 (GRCm38) |
I296F |
probably benign |
Het |
| Vps13a |
T |
C |
19: 16,655,304 (GRCm38) |
S2563G |
probably damaging |
Het |
| Wdr59 |
A |
G |
8: 111,494,280 (GRCm38) |
F207L |
|
Het |
| Zan |
A |
G |
5: 137,407,033 (GRCm38) |
S3777P |
unknown |
Het |
| Zfp277 |
T |
C |
12: 40,315,881 (GRCm38) |
N530D |
possibly damaging |
Het |
| Zfp365 |
G |
A |
10: 67,909,919 (GRCm38) |
R10W |
probably damaging |
Het |
| Zfp384 |
A |
T |
6: 125,036,325 (GRCm38) |
H452L |
probably damaging |
Het |
| Zftraf1 |
C |
T |
15: 76,648,186 (GRCm38) |
D241N |
probably benign |
Het |
| Zfyve28 |
A |
T |
5: 34,217,143 (GRCm38) |
L509Q |
probably damaging |
Het |
|
| Other mutations in Cux1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00846:Cux1
|
APN |
5 |
136,326,796 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL00966:Cux1
|
APN |
5 |
136,311,491 (GRCm38) |
intron |
probably benign |
|
|
IGL01129:Cux1
|
APN |
5 |
136,304,718 (GRCm38) |
intron |
probably benign |
|
|
IGL01885:Cux1
|
APN |
5 |
136,308,447 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
IGL01947:Cux1
|
APN |
5 |
136,275,125 (GRCm38) |
missense |
probably benign |
0.04 |
|
IGL02259:Cux1
|
APN |
5 |
136,326,833 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02666:Cux1
|
APN |
5 |
136,275,315 (GRCm38) |
nonsense |
probably null |
|
|
IGL02826:Cux1
|
APN |
5 |
136,308,003 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03014:Cux1
|
UTSW |
5 |
136,565,525 (GRCm38) |
intron |
probably benign |
|
|
R0047:Cux1
|
UTSW |
5 |
136,363,253 (GRCm38) |
splice site |
probably benign |
|
|
R0047:Cux1
|
UTSW |
5 |
136,363,253 (GRCm38) |
splice site |
probably benign |
|
|
R0057:Cux1
|
UTSW |
5 |
136,256,282 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0149:Cux1
|
UTSW |
5 |
136,279,497 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0295:Cux1
|
UTSW |
5 |
136,313,212 (GRCm38) |
missense |
probably benign |
0.04 |
|
R0361:Cux1
|
UTSW |
5 |
136,279,497 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0533:Cux1
|
UTSW |
5 |
136,307,859 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0630:Cux1
|
UTSW |
5 |
136,286,835 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0801:Cux1
|
UTSW |
5 |
136,326,929 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R0884:Cux1
|
UTSW |
5 |
136,307,835 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0976:Cux1
|
UTSW |
5 |
136,313,290 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1073:Cux1
|
UTSW |
5 |
136,252,541 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1222:Cux1
|
UTSW |
5 |
136,275,149 (GRCm38) |
missense |
probably benign |
0.18 |
|
R1518:Cux1
|
UTSW |
5 |
136,308,279 (GRCm38) |
missense |
probably benign |
0.29 |
|
R1686:Cux1
|
UTSW |
5 |
136,275,381 (GRCm38) |
nonsense |
probably null |
|
|
R1687:Cux1
|
UTSW |
5 |
136,312,669 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1758:Cux1
|
UTSW |
5 |
136,392,322 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1797:Cux1
|
UTSW |
5 |
136,275,315 (GRCm38) |
missense |
probably benign |
0.22 |
|
R1919:Cux1
|
UTSW |
5 |
136,363,319 (GRCm38) |
nonsense |
probably null |
|
|
R2051:Cux1
|
UTSW |
5 |
136,332,658 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2339:Cux1
|
UTSW |
5 |
136,287,008 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3438:Cux1
|
UTSW |
5 |
136,311,560 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R3713:Cux1
|
UTSW |
5 |
136,565,543 (GRCm38) |
intron |
probably benign |
|
|
R3800:Cux1
|
UTSW |
5 |
136,316,033 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3964:Cux1
|
UTSW |
5 |
136,282,942 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4135:Cux1
|
UTSW |
5 |
136,307,896 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4198:Cux1
|
UTSW |
5 |
136,286,848 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4467:Cux1
|
UTSW |
5 |
136,312,722 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4498:Cux1
|
UTSW |
5 |
136,312,993 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4622:Cux1
|
UTSW |
5 |
136,308,300 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4623:Cux1
|
UTSW |
5 |
136,308,300 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4651:Cux1
|
UTSW |
5 |
136,567,229 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4652:Cux1
|
UTSW |
5 |
136,567,229 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4658:Cux1
|
UTSW |
5 |
136,250,594 (GRCm38) |
missense |
possibly damaging |
0.80 |
|
R4665:Cux1
|
UTSW |
5 |
136,286,799 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4704:Cux1
|
UTSW |
5 |
136,249,201 (GRCm38) |
missense |
probably benign |
0.01 |
|
R4867:Cux1
|
UTSW |
5 |
136,274,961 (GRCm38) |
intron |
probably benign |
|
|
R4965:Cux1
|
UTSW |
5 |
136,311,556 (GRCm38) |
missense |
possibly damaging |
0.77 |
|
R5090:Cux1
|
UTSW |
5 |
136,313,200 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R5155:Cux1
|
UTSW |
5 |
136,565,441 (GRCm38) |
intron |
probably benign |
|
|
R5226:Cux1
|
UTSW |
5 |
136,370,173 (GRCm38) |
missense |
probably benign |
0.01 |
|
R5252:Cux1
|
UTSW |
5 |
136,308,297 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R5266:Cux1
|
UTSW |
5 |
136,312,694 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5399:Cux1
|
UTSW |
5 |
136,252,604 (GRCm38) |
missense |
possibly damaging |
0.58 |
|
R5509:Cux1
|
UTSW |
5 |
136,275,317 (GRCm38) |
missense |
probably benign |
0.13 |
|
R5609:Cux1
|
UTSW |
5 |
136,392,320 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5681:Cux1
|
UTSW |
5 |
136,308,184 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5993:Cux1
|
UTSW |
5 |
136,363,271 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6049:Cux1
|
UTSW |
5 |
136,332,710 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6290:Cux1
|
UTSW |
5 |
136,311,558 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R6310:Cux1
|
UTSW |
5 |
136,275,164 (GRCm38) |
missense |
probably benign |
0.10 |
|
R6351:Cux1
|
UTSW |
5 |
136,309,792 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6531:Cux1
|
UTSW |
5 |
136,275,119 (GRCm38) |
missense |
probably benign |
0.03 |
|
R6590:Cux1
|
UTSW |
5 |
136,340,117 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R6663:Cux1
|
UTSW |
5 |
136,485,847 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6690:Cux1
|
UTSW |
5 |
136,340,117 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R6777:Cux1
|
UTSW |
5 |
136,565,568 (GRCm38) |
intron |
probably benign |
|
|
R6786:Cux1
|
UTSW |
5 |
136,567,231 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6817:Cux1
|
UTSW |
5 |
136,373,173 (GRCm38) |
splice site |
probably null |
|
|
R6989:Cux1
|
UTSW |
5 |
136,279,648 (GRCm38) |
nonsense |
probably null |
|
|
R7011:Cux1
|
UTSW |
5 |
136,360,033 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7167:Cux1
|
UTSW |
5 |
136,310,041 (GRCm38) |
splice site |
probably null |
|
|
R7699:Cux1
|
UTSW |
5 |
136,485,739 (GRCm38) |
critical splice donor site |
probably null |
|
|
R7876:Cux1
|
UTSW |
5 |
136,363,307 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7916:Cux1
|
UTSW |
5 |
136,282,961 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8023:Cux1
|
UTSW |
5 |
136,373,397 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R8154:Cux1
|
UTSW |
5 |
136,252,580 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8267:Cux1
|
UTSW |
5 |
136,282,999 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8289:Cux1
|
UTSW |
5 |
136,308,504 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R8305:Cux1
|
UTSW |
5 |
136,360,009 (GRCm38) |
missense |
probably benign |
0.02 |
|
R8319:Cux1
|
UTSW |
5 |
136,565,397 (GRCm38) |
missense |
probably benign |
0.02 |
|
R8405:Cux1
|
UTSW |
5 |
136,275,387 (GRCm38) |
missense |
possibly damaging |
0.83 |
|
R8483:Cux1
|
UTSW |
5 |
136,275,090 (GRCm38) |
missense |
possibly damaging |
0.83 |
|
R8506:Cux1
|
UTSW |
5 |
136,308,504 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R8671:Cux1
|
UTSW |
5 |
136,250,600 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8680:Cux1
|
UTSW |
5 |
136,307,856 (GRCm38) |
missense |
possibly damaging |
0.46 |
|
R8737:Cux1
|
UTSW |
5 |
136,282,942 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8738:Cux1
|
UTSW |
5 |
136,373,366 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8793:Cux1
|
UTSW |
5 |
136,565,685 (GRCm38) |
missense |
unknown |
|
|
R8897:Cux1
|
UTSW |
5 |
136,286,769 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8926:Cux1
|
UTSW |
5 |
136,309,550 (GRCm38) |
intron |
probably benign |
|
|
R8954:Cux1
|
UTSW |
5 |
136,373,349 (GRCm38) |
nonsense |
probably null |
|
|
R9092:Cux1
|
UTSW |
5 |
136,485,817 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9205:Cux1
|
UTSW |
5 |
136,370,135 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9550:Cux1
|
UTSW |
5 |
136,311,533 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R9578:Cux1
|
UTSW |
5 |
136,254,065 (GRCm38) |
critical splice donor site |
probably null |
|
|
R9682:Cux1
|
UTSW |
5 |
136,308,262 (GRCm38) |
missense |
probably benign |
|
|
R9701:Cux1
|
UTSW |
5 |
136,314,315 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R9712:Cux1
|
UTSW |
5 |
136,309,819 (GRCm38) |
missense |
probably benign |
0.35 |
|
| Predicted Primers |
PCR Primer
(F):5'- AACTGTTGCTGTTCACTGGC -3'
(R):5'- TTAGCTCCCCAGTGGAACTG -3'
Sequencing Primer
(F):5'- CACAGTTTACATTACACCTGAGGGG -3'
(R):5'- TCCCCAGTGGAACTGTGACC -3'
|
| Posted On |
2019-12-20 |
Incidental Mutation