Incidental Mutation 'R7908:Jmjd1c'
| ID |
610293 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Jmjd1c
|
| Ensembl Gene |
ENSMUSG00000037876 |
| Gene Name |
jumonji domain containing 1C |
| Synonyms |
D630035I23Rik, TRIP8, 5430433L24Rik |
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.655)
|
| Stock # |
R7908 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
10 |
| Chromosomal Location |
66932189-67092105 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 67061621 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Proline
at position 1144
(S1144P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000133700
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000051446]
[ENSMUST00000173689]
[ENSMUST00000174317]
[ENSMUST00000174408]
|
| AlphaFold |
Q69ZK6 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000051446
AA Change: S1325P
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000056227
Gene: ENSMUSG00000037876
AA Change: S1325P
| Domain | Start | End | E-Value | Type |
|---|
|
Blast:JmjC
|
143 |
2236 |
N/A |
BLAST |
|
JmjC
|
2264 |
2488 |
3.29e-53 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000173689
AA Change: S1144P
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000133700
Gene: ENSMUSG00000037876
AA Change: S1144P
| Domain | Start | End | E-Value | Type |
|---|
|
Blast:JmjC
|
1 |
2056 |
N/A |
BLAST |
|
JmjC
|
2084 |
2308 |
3.29e-53 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000174317
|
| SMART Domains |
Protein: ENSMUSP00000134246
Gene: ENSMUSG00000037876
| Domain | Start | End | E-Value | Type |
|---|
|
Blast:JmjC
|
1 |
744 |
N/A |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000174408
AA Change: S1325P
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000134551
Gene: ENSMUSG00000037876
AA Change: S1325P
| Domain | Start | End | E-Value | Type |
|---|
|
Blast:JmjC
|
143 |
2237 |
N/A |
BLAST |
|
JmjC
|
2265 |
2489 |
3.29e-53 |
SMART |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.6%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene interacts with thyroid hormone receptors and contains a jumonji domain. It is a candidate histone demethylase and is thought to be a coactivator for key transcription factors. It plays a role in the DNA-damage response pathway by demethylating the mediator of DNA damage checkpoint 1 (MDC1) protein, and is required for the survival of acute myeloid leukemia. Mutations in this gene are associated with Rett syndrome and intellectual disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
PHENOTYPE: Mice homozygous for a null allele exhibit an age-dependent male infertility phenotype, characterized by early loss of undifferentiated spermatogonia, and a progressive reduction in testis size/weight and male germ cells, partly due to increased male germ cell apoptosis. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 77 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| A4galt |
A |
G |
15: 83,112,577 (GRCm39) |
F69L |
probably benign |
Het |
| Acsf3 |
A |
G |
8: 123,512,562 (GRCm39) |
M328V |
probably damaging |
Het |
| Adam10 |
T |
G |
9: 70,669,046 (GRCm39) |
V454G |
possibly damaging |
Het |
| Adamts15 |
T |
C |
9: 30,813,522 (GRCm39) |
D881G |
probably benign |
Het |
| Adamtsl1 |
T |
C |
4: 86,274,676 (GRCm39) |
V1244A |
probably benign |
Het |
| Ankfn1 |
G |
A |
11: 89,296,360 (GRCm39) |
P123L |
probably damaging |
Het |
| Aox1 |
T |
C |
1: 58,145,227 (GRCm39) |
I1331T |
possibly damaging |
Het |
| Atg14 |
T |
A |
14: 47,806,050 (GRCm39) |
|
probably benign |
Het |
| Bmal1 |
A |
T |
7: 112,912,680 (GRCm39) |
I579L |
probably benign |
Het |
| Btnl4 |
A |
G |
17: 34,692,161 (GRCm39) |
M147T |
possibly damaging |
Het |
| Camk1g |
T |
C |
1: 193,042,082 (GRCm39) |
K56E |
probably damaging |
Het |
| Capn7 |
T |
C |
14: 31,088,202 (GRCm39) |
|
probably null |
Het |
| Cbln1 |
T |
A |
8: 88,198,724 (GRCm39) |
T49S |
probably benign |
Het |
| Cc2d2a |
T |
C |
5: 43,864,188 (GRCm39) |
V763A |
probably benign |
Het |
| Cdc40 |
A |
G |
10: 40,724,042 (GRCm39) |
Y249H |
probably damaging |
Het |
| Cfap61 |
T |
A |
2: 145,944,019 (GRCm39) |
L762H |
probably damaging |
Het |
| Cfap68 |
T |
A |
9: 50,675,248 (GRCm39) |
T153S |
possibly damaging |
Het |
| Cfap73 |
T |
C |
5: 120,768,123 (GRCm39) |
T212A |
probably benign |
Het |
| Cfi |
A |
G |
3: 129,642,233 (GRCm39) |
E29G |
probably benign |
Het |
| Chmp6 |
A |
T |
11: 119,804,656 (GRCm39) |
|
probably benign |
Het |
| Clec14a |
T |
C |
12: 58,314,465 (GRCm39) |
T386A |
possibly damaging |
Het |
| Coq6 |
T |
A |
12: 84,417,940 (GRCm39) |
L268H |
probably damaging |
Het |
| Cpt1a |
T |
C |
19: 3,412,202 (GRCm39) |
S225P |
probably benign |
Het |
| Dhx58 |
C |
A |
11: 100,586,130 (GRCm39) |
L630F |
probably damaging |
Het |
| Dlg2 |
T |
A |
7: 91,549,981 (GRCm39) |
V158E |
probably damaging |
Het |
| Fcgbpl1 |
A |
T |
7: 27,846,921 (GRCm39) |
Y1168F |
probably benign |
Het |
| Foxd3 |
A |
G |
4: 99,545,576 (GRCm39) |
T239A |
probably benign |
Het |
| Galnt6 |
T |
C |
15: 100,601,242 (GRCm39) |
T346A |
probably damaging |
Het |
| Guca1b |
C |
G |
17: 47,702,102 (GRCm39) |
T185S |
unknown |
Het |
| H2-M5 |
T |
C |
17: 37,298,571 (GRCm39) |
T292A |
probably benign |
Het |
| Hlx |
T |
C |
1: 184,459,773 (GRCm39) |
H455R |
probably benign |
Het |
| Hydin |
A |
G |
8: 111,237,499 (GRCm39) |
Y1924C |
probably benign |
Het |
| Ighg2b |
C |
T |
12: 113,270,074 (GRCm39) |
V315M |
|
Het |
| Ildr2 |
A |
G |
1: 166,135,369 (GRCm39) |
K374E |
probably damaging |
Het |
| Kcnj8 |
T |
C |
6: 142,511,755 (GRCm39) |
D284G |
probably benign |
Het |
| Kri1 |
TTCCTCCTCCTCCTCCTCCTCCTCCTCCTC |
TTCCTCCTCCTCCTCCTCCTCCTCCTC |
9: 21,192,352 (GRCm39) |
|
probably benign |
Het |
| Lingo4 |
A |
G |
3: 94,309,541 (GRCm39) |
T160A |
probably benign |
Het |
| Lmod3 |
G |
T |
6: 97,225,434 (GRCm39) |
A129E |
probably benign |
Het |
| Lrrk2 |
T |
C |
15: 91,610,355 (GRCm39) |
C696R |
probably damaging |
Het |
| Mc2r |
A |
G |
18: 68,541,036 (GRCm39) |
F86L |
probably benign |
Het |
| Mppe1 |
T |
G |
18: 67,362,055 (GRCm39) |
K170T |
probably benign |
Het |
| Mtcl1 |
A |
G |
17: 66,678,325 (GRCm39) |
I667T |
possibly damaging |
Het |
| Mtnr1a |
A |
T |
8: 45,540,863 (GRCm39) |
I275F |
probably benign |
Het |
| Myh2 |
A |
G |
11: 67,088,197 (GRCm39) |
I1938V |
probably benign |
Het |
| Npsr1 |
A |
T |
9: 24,201,096 (GRCm39) |
E160V |
probably damaging |
Het |
| Or13c7b |
T |
A |
4: 43,821,086 (GRCm39) |
I92F |
probably damaging |
Het |
| Or5ac23 |
C |
T |
16: 59,149,606 (GRCm39) |
D89N |
possibly damaging |
Het |
| Or6c3 |
T |
A |
10: 129,308,867 (GRCm39) |
I102N |
probably damaging |
Het |
| Ovch2 |
T |
A |
7: 107,388,326 (GRCm39) |
Y418F |
probably damaging |
Het |
| Pak5 |
A |
G |
2: 135,958,479 (GRCm39) |
L203S |
probably benign |
Het |
| Pcdh15 |
A |
T |
10: 74,479,414 (GRCm39) |
E508D |
probably benign |
Het |
| Prl7a1 |
T |
C |
13: 27,826,433 (GRCm39) |
M1V |
probably null |
Het |
| Prorp |
A |
T |
12: 55,426,250 (GRCm39) |
K533N |
possibly damaging |
Het |
| Prpsap2 |
G |
T |
11: 61,647,098 (GRCm39) |
N14K |
possibly damaging |
Het |
| Rad54b |
T |
A |
4: 11,595,868 (GRCm39) |
V215E |
probably null |
Het |
| Ryr2 |
G |
A |
13: 11,807,634 (GRCm39) |
T845I |
probably benign |
Het |
| Scgb2b3 |
G |
A |
7: 31,061,439 (GRCm39) |
T20I |
probably damaging |
Het |
| Serpina1b |
T |
C |
12: 103,694,566 (GRCm39) |
I393V |
possibly damaging |
Het |
| Slc13a5 |
T |
C |
11: 72,149,890 (GRCm39) |
M207V |
probably benign |
Het |
| Slc49a3 |
T |
C |
5: 108,592,363 (GRCm39) |
I276V |
probably benign |
Het |
| Smg1 |
A |
T |
7: 117,785,357 (GRCm39) |
L843M |
unknown |
Het |
| Sp100 |
T |
C |
1: 85,635,788 (GRCm39) |
V531A |
possibly damaging |
Het |
| Srsf6 |
T |
C |
2: 162,775,760 (GRCm39) |
S190P |
unknown |
Het |
| Stil |
A |
G |
4: 114,889,896 (GRCm39) |
K795E |
possibly damaging |
Het |
| Sugp2 |
A |
G |
8: 70,704,577 (GRCm39) |
R705G |
probably benign |
Het |
| Tnfrsf11a |
T |
A |
1: 105,737,099 (GRCm39) |
C69S |
probably damaging |
Het |
| Trim30a |
A |
T |
7: 104,070,656 (GRCm39) |
N252K |
probably benign |
Het |
| Tshz1 |
T |
A |
18: 84,032,732 (GRCm39) |
K559* |
probably null |
Het |
| Ttbk1 |
C |
T |
17: 46,789,864 (GRCm39) |
R133H |
probably damaging |
Het |
| Vmn1r1 |
T |
C |
1: 181,984,915 (GRCm39) |
Y250C |
probably benign |
Het |
| Vmn2r12 |
A |
G |
5: 109,234,307 (GRCm39) |
L635P |
probably damaging |
Het |
| Vmn2r52 |
C |
A |
7: 9,896,877 (GRCm39) |
V532L |
probably benign |
Het |
| Vwa5b1 |
A |
T |
4: 138,296,481 (GRCm39) |
L1182* |
probably null |
Het |
| Washc2 |
A |
G |
6: 116,225,106 (GRCm39) |
D818G |
probably benign |
Het |
| Xylb |
T |
G |
9: 119,210,611 (GRCm39) |
S365A |
probably benign |
Het |
| Zcchc8 |
T |
C |
5: 123,858,783 (GRCm39) |
|
probably benign |
Het |
| Zdbf2 |
T |
C |
1: 63,345,986 (GRCm39) |
I1455T |
possibly damaging |
Het |
|
| Other mutations in Jmjd1c |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01062:Jmjd1c
|
APN |
10 |
67,062,494 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01604:Jmjd1c
|
APN |
10 |
67,085,541 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01753:Jmjd1c
|
APN |
10 |
67,067,794 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02081:Jmjd1c
|
APN |
10 |
67,055,305 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02128:Jmjd1c
|
APN |
10 |
67,079,648 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02134:Jmjd1c
|
APN |
10 |
67,056,171 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL02215:Jmjd1c
|
APN |
10 |
67,056,101 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02408:Jmjd1c
|
APN |
10 |
67,062,161 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02502:Jmjd1c
|
APN |
10 |
67,061,640 (GRCm39) |
missense |
probably benign |
0.13 |
|
IGL02546:Jmjd1c
|
APN |
10 |
67,061,115 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL02943:Jmjd1c
|
APN |
10 |
67,055,433 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03171:Jmjd1c
|
APN |
10 |
67,061,277 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL03261:Jmjd1c
|
APN |
10 |
67,067,849 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Accordion
|
UTSW |
10 |
67,069,193 (GRCm39) |
missense |
probably damaging |
0.99 |
|
PIT4378001:Jmjd1c
|
UTSW |
10 |
67,065,692 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0126:Jmjd1c
|
UTSW |
10 |
67,055,105 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0133:Jmjd1c
|
UTSW |
10 |
67,076,587 (GRCm39) |
missense |
probably benign |
0.22 |
|
R0201:Jmjd1c
|
UTSW |
10 |
67,054,888 (GRCm39) |
missense |
unknown |
|
|
R0396:Jmjd1c
|
UTSW |
10 |
67,055,302 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R0401:Jmjd1c
|
UTSW |
10 |
67,056,161 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0452:Jmjd1c
|
UTSW |
10 |
67,091,261 (GRCm39) |
missense |
probably benign |
0.28 |
|
R0488:Jmjd1c
|
UTSW |
10 |
67,076,506 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0504:Jmjd1c
|
UTSW |
10 |
67,061,534 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0555:Jmjd1c
|
UTSW |
10 |
67,061,568 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0673:Jmjd1c
|
UTSW |
10 |
67,062,588 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0718:Jmjd1c
|
UTSW |
10 |
67,054,725 (GRCm39) |
splice site |
probably null |
|
|
R0755:Jmjd1c
|
UTSW |
10 |
66,932,378 (GRCm39) |
intron |
probably benign |
|
|
R1142:Jmjd1c
|
UTSW |
10 |
67,061,124 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1196:Jmjd1c
|
UTSW |
10 |
67,075,015 (GRCm39) |
splice site |
probably benign |
|
|
R1413:Jmjd1c
|
UTSW |
10 |
67,085,529 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1619:Jmjd1c
|
UTSW |
10 |
67,055,654 (GRCm39) |
missense |
probably benign |
0.25 |
|
R1676:Jmjd1c
|
UTSW |
10 |
67,060,588 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1751:Jmjd1c
|
UTSW |
10 |
67,061,469 (GRCm39) |
missense |
probably benign |
|
|
R1950:Jmjd1c
|
UTSW |
10 |
67,075,701 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R1968:Jmjd1c
|
UTSW |
10 |
67,061,219 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2049:Jmjd1c
|
UTSW |
10 |
66,993,777 (GRCm39) |
nonsense |
probably null |
|
|
R2061:Jmjd1c
|
UTSW |
10 |
67,054,205 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2202:Jmjd1c
|
UTSW |
10 |
67,075,242 (GRCm39) |
splice site |
probably null |
|
|
R2203:Jmjd1c
|
UTSW |
10 |
67,075,242 (GRCm39) |
splice site |
probably null |
|
|
R2256:Jmjd1c
|
UTSW |
10 |
67,061,073 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2312:Jmjd1c
|
UTSW |
10 |
67,074,629 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2349:Jmjd1c
|
UTSW |
10 |
67,091,279 (GRCm39) |
missense |
probably benign |
|
|
R2392:Jmjd1c
|
UTSW |
10 |
67,065,683 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3015:Jmjd1c
|
UTSW |
10 |
66,993,711 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3110:Jmjd1c
|
UTSW |
10 |
67,075,863 (GRCm39) |
splice site |
probably benign |
|
|
R4043:Jmjd1c
|
UTSW |
10 |
67,055,245 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R4097:Jmjd1c
|
UTSW |
10 |
67,054,787 (GRCm39) |
missense |
probably benign |
0.09 |
|
R4118:Jmjd1c
|
UTSW |
10 |
67,055,532 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4193:Jmjd1c
|
UTSW |
10 |
66,932,460 (GRCm39) |
intron |
probably benign |
|
|
R4352:Jmjd1c
|
UTSW |
10 |
67,080,588 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4577:Jmjd1c
|
UTSW |
10 |
67,085,529 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4630:Jmjd1c
|
UTSW |
10 |
66,993,753 (GRCm39) |
nonsense |
probably null |
|
|
R4717:Jmjd1c
|
UTSW |
10 |
66,993,830 (GRCm39) |
nonsense |
probably null |
|
|
R4741:Jmjd1c
|
UTSW |
10 |
67,060,718 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R4774:Jmjd1c
|
UTSW |
10 |
67,060,571 (GRCm39) |
missense |
possibly damaging |
0.45 |
|
R4836:Jmjd1c
|
UTSW |
10 |
67,069,225 (GRCm39) |
missense |
probably benign |
0.21 |
|
R4914:Jmjd1c
|
UTSW |
10 |
67,054,750 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4939:Jmjd1c
|
UTSW |
10 |
67,081,916 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R5211:Jmjd1c
|
UTSW |
10 |
67,067,795 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5215:Jmjd1c
|
UTSW |
10 |
67,076,480 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R5514:Jmjd1c
|
UTSW |
10 |
67,053,928 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5530:Jmjd1c
|
UTSW |
10 |
67,085,541 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5624:Jmjd1c
|
UTSW |
10 |
67,069,193 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5640:Jmjd1c
|
UTSW |
10 |
67,061,857 (GRCm39) |
missense |
probably benign |
0.10 |
|
R5654:Jmjd1c
|
UTSW |
10 |
67,065,785 (GRCm39) |
missense |
probably benign |
0.10 |
|
R5742:Jmjd1c
|
UTSW |
10 |
67,056,112 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5764:Jmjd1c
|
UTSW |
10 |
67,062,291 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6118:Jmjd1c
|
UTSW |
10 |
67,075,791 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6163:Jmjd1c
|
UTSW |
10 |
67,083,827 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6256:Jmjd1c
|
UTSW |
10 |
67,056,187 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6266:Jmjd1c
|
UTSW |
10 |
67,085,439 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6358:Jmjd1c
|
UTSW |
10 |
67,061,718 (GRCm39) |
missense |
probably benign |
|
|
R6430:Jmjd1c
|
UTSW |
10 |
67,059,939 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R6455:Jmjd1c
|
UTSW |
10 |
67,061,795 (GRCm39) |
missense |
probably benign |
0.10 |
|
R6887:Jmjd1c
|
UTSW |
10 |
67,025,599 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R6895:Jmjd1c
|
UTSW |
10 |
67,052,869 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7041:Jmjd1c
|
UTSW |
10 |
67,056,388 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7095:Jmjd1c
|
UTSW |
10 |
67,055,411 (GRCm39) |
missense |
probably benign |
0.39 |
|
R7113:Jmjd1c
|
UTSW |
10 |
66,993,780 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7225:Jmjd1c
|
UTSW |
10 |
67,061,844 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7249:Jmjd1c
|
UTSW |
10 |
67,025,596 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7361:Jmjd1c
|
UTSW |
10 |
67,054,143 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7383:Jmjd1c
|
UTSW |
10 |
67,025,537 (GRCm39) |
missense |
probably benign |
0.14 |
|
R7460:Jmjd1c
|
UTSW |
10 |
67,052,815 (GRCm39) |
missense |
probably benign |
0.24 |
|
R7475:Jmjd1c
|
UTSW |
10 |
67,061,092 (GRCm39) |
missense |
probably benign |
0.22 |
|
R7502:Jmjd1c
|
UTSW |
10 |
67,067,794 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7699:Jmjd1c
|
UTSW |
10 |
67,054,195 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7745:Jmjd1c
|
UTSW |
10 |
67,052,824 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7897:Jmjd1c
|
UTSW |
10 |
67,075,644 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7911:Jmjd1c
|
UTSW |
10 |
67,067,774 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7967:Jmjd1c
|
UTSW |
10 |
67,085,461 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8058:Jmjd1c
|
UTSW |
10 |
67,090,274 (GRCm39) |
missense |
not run |
|
|
R8224:Jmjd1c
|
UTSW |
10 |
67,080,628 (GRCm39) |
missense |
noncoding transcript |
|
|
R8251:Jmjd1c
|
UTSW |
10 |
67,075,068 (GRCm39) |
missense |
noncoding transcript |
|
|
R8797:Jmjd1c
|
UTSW |
10 |
67,060,616 (GRCm39) |
missense |
probably benign |
|
|
R8833:Jmjd1c
|
UTSW |
10 |
67,054,162 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9262:Jmjd1c
|
UTSW |
10 |
67,083,793 (GRCm39) |
missense |
probably benign |
0.39 |
|
R9354:Jmjd1c
|
UTSW |
10 |
67,059,875 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9373:Jmjd1c
|
UTSW |
10 |
66,932,495 (GRCm39) |
intron |
probably benign |
|
|
R9477:Jmjd1c
|
UTSW |
10 |
66,993,734 (GRCm39) |
nonsense |
probably null |
|
|
R9519:Jmjd1c
|
UTSW |
10 |
66,993,798 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R9701:Jmjd1c
|
UTSW |
10 |
67,060,745 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R9802:Jmjd1c
|
UTSW |
10 |
67,060,745 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
RF011:Jmjd1c
|
UTSW |
10 |
67,055,978 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
Z1088:Jmjd1c
|
UTSW |
10 |
67,073,953 (GRCm39) |
missense |
probably benign |
|
|
Z1176:Jmjd1c
|
UTSW |
10 |
67,073,953 (GRCm39) |
missense |
probably benign |
|
|
Z1177:Jmjd1c
|
UTSW |
10 |
67,081,904 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Z1177:Jmjd1c
|
UTSW |
10 |
67,073,953 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- GTGGAGATCTAATAACAACCTCAAC -3'
(R):5'- TCAAGCTGGAGACACTGGTG -3'
Sequencing Primer
(F):5'- ACCTCAACAGAGAGAAAGCTG -3'
(R):5'- CACATCTGCTTTGGTAGTAGAGAC -3'
|
| Posted On |
2019-12-20 |
Incidental Mutation