Incidental Mutation 'R7912:Aox3'
| ID |
610547 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Aox3
|
| Ensembl Gene |
ENSMUSG00000064294 |
| Gene Name |
aldehyde oxidase 3 |
| Synonyms |
1200011D03Rik, AOH1 |
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7912 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
1 |
| Chromosomal Location |
58152289-58239857 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 58181855 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Threonine
at position 281
(S281T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000049391
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000040999]
[ENSMUST00000162011]
|
| AlphaFold |
G3X982 |
| PDB Structure |
Crystal structure of the mouse liver Aldehyde Oxidase 3 (mAOX3) [X-RAY DIFFRACTION]
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000040999
AA Change: S281T
PolyPhen 2
Score 0.046 (Sensitivity: 0.94; Specificity: 0.83)
|
| SMART Domains |
Protein: ENSMUSP00000049391
Gene: ENSMUSG00000064294
AA Change: S281T
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Fer2
|
12 |
82 |
1.4e-9 |
PFAM |
|
Pfam:Fer2_2
|
91 |
165 |
1e-29 |
PFAM |
|
Pfam:FAD_binding_5
|
239 |
419 |
1e-44 |
PFAM |
|
CO_deh_flav_C
|
426 |
530 |
9.26e-24 |
SMART |
|
Ald_Xan_dh_C
|
594 |
697 |
2.27e-41 |
SMART |
|
Pfam:Ald_Xan_dh_C2
|
708 |
1241 |
8.7e-183 |
PFAM |
|
low complexity region
|
1275 |
1286 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000162011
|
| SMART Domains |
Protein: ENSMUSP00000140140
Gene: ENSMUSG00000064294
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Fer2
|
12 |
82 |
3.6e-8 |
PFAM |
|
Pfam:Fer2_2
|
91 |
166 |
2.5e-29 |
PFAM |
|
transmembrane domain
|
242 |
264 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.6%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 90 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2310003L06Rik |
A |
G |
5: 88,120,451 (GRCm39) |
T403A |
probably benign |
Het |
| Aco1 |
T |
C |
4: 40,184,983 (GRCm39) |
L551S |
probably damaging |
Het |
| Acvr1 |
C |
T |
2: 58,364,230 (GRCm39) |
V200I |
probably damaging |
Het |
| Adam26b |
T |
A |
8: 43,973,245 (GRCm39) |
T586S |
probably benign |
Het |
| Ahctf1 |
T |
C |
1: 179,580,656 (GRCm39) |
R1849G |
probably benign |
Het |
| Alox5 |
T |
A |
6: 116,389,497 (GRCm39) |
D590V |
probably benign |
Het |
| Anapc5 |
A |
G |
5: 122,931,498 (GRCm39) |
|
probably null |
Het |
| Anln |
T |
C |
9: 22,269,965 (GRCm39) |
E743G |
possibly damaging |
Het |
| Anpep |
T |
C |
7: 79,488,174 (GRCm39) |
K496R |
probably benign |
Het |
| Arhgef11 |
C |
A |
3: 87,640,529 (GRCm39) |
P1258T |
probably damaging |
Het |
| Atp2c2 |
A |
T |
8: 120,456,917 (GRCm39) |
D173V |
possibly damaging |
Het |
| Aurka |
T |
G |
2: 172,210,949 (GRCm39) |
D22A |
probably benign |
Het |
| B3gat1 |
A |
T |
9: 26,666,882 (GRCm39) |
D51V |
probably benign |
Het |
| BC028528 |
CTCACTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTT |
CTCACTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTT |
3: 95,795,448 (GRCm39) |
|
probably benign |
Het |
| BC028528 |
TGGTTCTGTGGTCAC |
TGGTTCTGTGGTCACGGGTTCTGTGGTCAC |
3: 95,795,483 (GRCm39) |
|
probably benign |
Het |
| BC028528 |
ACTGGTTCTGTGGTCACTGGTTCTGTGGTC |
ACTGGTTCTGTGGTCGCTGGTTCTGTGGTCACTGGTTCTGTGGTC |
3: 95,795,466 (GRCm39) |
|
probably benign |
Het |
| BC028528 |
TTC |
TTCGGTGGTCACTGGCTC |
3: 95,795,456 (GRCm39) |
|
probably benign |
Het |
| BC028528 |
GGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTTCTGTGGTCACT |
GGTTCTGTGGTCACTTGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTTCTGTGGTCACT |
3: 95,795,454 (GRCm39) |
|
probably benign |
Het |
| BC028528 |
CTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTTCTGTGGTCA |
CTGGTTCTGTGGTCAATGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTTCTGTGGTCA |
3: 95,795,452 (GRCm39) |
|
probably benign |
Het |
| BC028528 |
CACTG |
CACTGATTCTGTGGTGACTG |
3: 95,795,450 (GRCm39) |
|
probably benign |
Het |
| Bcas3 |
G |
A |
11: 85,261,954 (GRCm39) |
G96S |
probably damaging |
Het |
| Bltp1 |
C |
T |
3: 37,061,218 (GRCm39) |
A3309V |
probably damaging |
Het |
| C2cd4d |
T |
A |
3: 94,270,860 (GRCm39) |
V42D |
probably damaging |
Het |
| Ccdc127 |
T |
C |
13: 74,505,151 (GRCm39) |
L233P |
probably damaging |
Het |
| Cdc42bpa |
A |
G |
1: 179,921,578 (GRCm39) |
K573E |
probably damaging |
Het |
| Cend1 |
T |
C |
7: 141,007,544 (GRCm39) |
D92G |
probably damaging |
Het |
| Crb1 |
T |
C |
1: 139,170,909 (GRCm39) |
D827G |
probably damaging |
Het |
| Cyld |
G |
T |
8: 89,461,525 (GRCm39) |
C654F |
probably damaging |
Het |
| Fastkd5 |
C |
T |
2: 130,458,557 (GRCm39) |
G11D |
probably damaging |
Het |
| Foxj3 |
A |
T |
4: 119,477,252 (GRCm39) |
N354I |
possibly damaging |
Het |
| Gimap8 |
G |
T |
6: 48,627,999 (GRCm39) |
C252F |
probably benign |
Het |
| Glra1 |
T |
C |
11: 55,411,821 (GRCm39) |
Y329C |
probably damaging |
Het |
| Gm10330 |
G |
A |
12: 23,829,980 (GRCm39) |
P67L |
probably benign |
Het |
| Gpm6a |
T |
C |
8: 55,508,469 (GRCm39) |
I226T |
possibly damaging |
Het |
| Gstt2 |
A |
G |
10: 75,668,418 (GRCm39) |
F121S |
probably benign |
Het |
| Hjurp |
TCTGGGAGGGCTTGCTCCGGGGGCAGTGTGTCCTGTTCTTGTGCAGCCCCTGCT |
TCT |
1: 88,194,000 (GRCm39) |
|
probably benign |
Het |
| Hmcn2 |
T |
C |
2: 31,310,311 (GRCm39) |
F3302L |
probably benign |
Het |
| Hormad2 |
T |
C |
11: 4,358,841 (GRCm39) |
T189A |
probably damaging |
Het |
| Hps5 |
A |
T |
7: 46,418,826 (GRCm39) |
S815T |
probably benign |
Het |
| Hydin |
G |
T |
8: 111,282,239 (GRCm39) |
R3113L |
possibly damaging |
Het |
| Inava |
A |
G |
1: 136,155,279 (GRCm39) |
S109P |
probably benign |
Het |
| Inpp5f |
T |
A |
7: 128,294,037 (GRCm39) |
C698S |
probably benign |
Het |
| Irs1 |
T |
G |
1: 82,267,605 (GRCm39) |
M204L |
probably benign |
Het |
| Itfg1 |
T |
C |
8: 86,490,909 (GRCm39) |
D340G |
probably damaging |
Het |
| Itm2c |
T |
A |
1: 85,833,032 (GRCm39) |
I122N |
probably damaging |
Het |
| Lamp3 |
T |
A |
16: 19,474,247 (GRCm39) |
T376S |
probably damaging |
Het |
| Lrba |
T |
A |
3: 86,622,872 (GRCm39) |
I2418N |
probably damaging |
Het |
| Lrcol1 |
T |
A |
5: 110,502,715 (GRCm39) |
V161D |
probably damaging |
Het |
| Lrp2 |
T |
A |
2: 69,259,016 (GRCm39) |
Q4558L |
probably benign |
Het |
| Lrrfip2 |
A |
T |
9: 111,034,836 (GRCm39) |
Q175L |
probably damaging |
Het |
| Mib1 |
T |
G |
18: 10,778,187 (GRCm39) |
S572R |
probably damaging |
Het |
| Mis18bp1 |
A |
T |
12: 65,199,532 (GRCm39) |
D456E |
possibly damaging |
Het |
| Mlh1 |
T |
A |
9: 111,090,581 (GRCm39) |
T116S |
possibly damaging |
Het |
| Mpp4 |
T |
C |
1: 59,160,521 (GRCm39) |
N594S |
probably damaging |
Het |
| Nbas |
A |
G |
12: 13,455,458 (GRCm39) |
E1224G |
possibly damaging |
Het |
| Neb |
T |
C |
2: 52,110,997 (GRCm39) |
D163G |
possibly damaging |
Het |
| Nectin4 |
T |
C |
1: 171,207,941 (GRCm39) |
V111A |
possibly damaging |
Het |
| Nfatc2ip |
G |
A |
7: 125,989,617 (GRCm39) |
R256* |
probably null |
Het |
| Nlgn2 |
G |
A |
11: 69,716,760 (GRCm39) |
R594C |
probably damaging |
Het |
| Nufip1 |
A |
G |
14: 76,352,442 (GRCm39) |
S198G |
possibly damaging |
Het |
| Or2n1 |
T |
C |
17: 38,486,158 (GRCm39) |
F61S |
probably damaging |
Het |
| Or5ac23 |
C |
T |
16: 59,149,606 (GRCm39) |
D89N |
possibly damaging |
Het |
| Or8b49 |
T |
C |
9: 38,506,446 (GRCm39) |
F310L |
probably benign |
Het |
| Or8s8 |
C |
T |
15: 98,354,574 (GRCm39) |
H128Y |
probably benign |
Het |
| Pcdhga8 |
G |
A |
18: 37,859,896 (GRCm39) |
M317I |
probably benign |
Het |
| Phactr1 |
A |
T |
13: 42,863,239 (GRCm39) |
I55L |
probably benign |
Het |
| Prl3c1 |
G |
A |
13: 27,383,367 (GRCm39) |
R31Q |
probably benign |
Het |
| Prss55 |
A |
T |
14: 64,319,180 (GRCm39) |
F59Y |
possibly damaging |
Het |
| Ptprb |
T |
C |
10: 116,158,392 (GRCm39) |
W488R |
probably damaging |
Het |
| Qrich2 |
GAAACCAGGCTGATCTGCCCCAGGCTGCAACAAACCAGGCTGATCTGCCCCAGGCTGCAACAAACCAGGCTGATCTGCCCCAGGCTGCAACAAACCAGGCTGATCTGTCCCAGGCTGCAACAAACCAGGCTGATC |
GAAACCAGGCTGATCTGCCCCAGGCTGCAACAAACCAGGCTGATCTGCCCCAGGCTGCAACAAACCAGGCTGATCTGTCCCAGGCTGCAACAAACCAGGCTGATC |
11: 116,346,608 (GRCm39) |
|
probably benign |
Het |
| Ros1 |
G |
T |
10: 52,044,791 (GRCm39) |
T172K |
probably damaging |
Het |
| Rtel1 |
C |
T |
2: 180,997,869 (GRCm39) |
R1206W |
possibly damaging |
Het |
| Slf2 |
A |
T |
19: 44,930,682 (GRCm39) |
K586N |
probably damaging |
Het |
| Smc2 |
T |
A |
4: 52,450,854 (GRCm39) |
M224K |
probably benign |
Het |
| Spata31d1e |
A |
T |
13: 59,890,329 (GRCm39) |
I497K |
probably damaging |
Het |
| Spinkl |
T |
C |
18: 44,299,716 (GRCm39) |
Y83C |
probably damaging |
Het |
| Srgap1 |
CTACCTCCTCTTAGGGACCACGCCCACCCCCTCCCAGGGACCATGCTTACCTCCTCTTAGGGACCACGCCCACCCCCTCCCAGGGACCATGCTTACCTCCTC |
CTACCTCCTCTTAGGGACCACGCCCACCCCCTCCCAGGGACCATGCTTACCTCCTC |
10: 121,689,458 (GRCm39) |
|
probably benign |
Het |
| St13 |
T |
C |
15: 81,283,719 (GRCm39) |
E26G |
possibly damaging |
Het |
| Teddm3 |
T |
A |
16: 20,971,699 (GRCm39) |
Q290L |
probably benign |
Het |
| Tfec |
C |
A |
6: 16,840,467 (GRCm39) |
|
probably null |
Het |
| Trank1 |
C |
A |
9: 111,220,596 (GRCm39) |
D2444E |
probably benign |
Het |
| Ttc17 |
T |
A |
2: 94,209,166 (GRCm39) |
N96I |
probably damaging |
Het |
| Ttn |
T |
C |
2: 76,560,130 (GRCm39) |
T29424A |
possibly damaging |
Het |
| Tut7 |
C |
A |
13: 59,946,819 (GRCm39) |
Q1003H |
probably damaging |
Het |
| Vmn1r68 |
G |
A |
7: 10,261,237 (GRCm39) |
T287I |
probably benign |
Het |
| Vmn2r52 |
C |
A |
7: 9,896,877 (GRCm39) |
V532L |
probably benign |
Het |
| Vmn2r92 |
A |
T |
17: 18,404,970 (GRCm39) |
T705S |
possibly damaging |
Het |
| Vps13d |
T |
C |
4: 144,899,697 (GRCm39) |
D200G |
|
Het |
| Wdr48 |
G |
A |
9: 119,733,405 (GRCm39) |
C84Y |
probably damaging |
Het |
| Zscan25 |
T |
A |
5: 145,227,321 (GRCm39) |
H328Q |
probably benign |
Het |
|
| Other mutations in Aox3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01599:Aox3
|
APN |
1 |
58,208,953 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01747:Aox3
|
APN |
1 |
58,198,817 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL01883:Aox3
|
APN |
1 |
58,177,442 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01911:Aox3
|
APN |
1 |
58,191,719 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL02017:Aox3
|
APN |
1 |
58,160,151 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02120:Aox3
|
APN |
1 |
58,166,809 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02466:Aox3
|
APN |
1 |
58,197,431 (GRCm39) |
missense |
probably benign |
0.28 |
|
IGL02545:Aox3
|
APN |
1 |
58,222,645 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02572:Aox3
|
APN |
1 |
58,197,526 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02746:Aox3
|
APN |
1 |
58,222,701 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
IGL02808:Aox3
|
APN |
1 |
58,181,859 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02812:Aox3
|
APN |
1 |
58,205,055 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02982:Aox3
|
APN |
1 |
58,166,846 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03056:Aox3
|
APN |
1 |
58,198,180 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL03182:Aox3
|
APN |
1 |
58,205,046 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL03234:Aox3
|
APN |
1 |
58,191,845 (GRCm39) |
missense |
probably benign |
|
|
IGL03374:Aox3
|
APN |
1 |
58,211,007 (GRCm39) |
missense |
probably damaging |
1.00 |
|
amber
|
UTSW |
1 |
58,211,050 (GRCm39) |
nonsense |
probably null |
|
|
R0071:Aox3
|
UTSW |
1 |
58,211,050 (GRCm39) |
nonsense |
probably null |
|
|
R0071:Aox3
|
UTSW |
1 |
58,211,050 (GRCm39) |
nonsense |
probably null |
|
|
R0135:Aox3
|
UTSW |
1 |
58,164,247 (GRCm39) |
splice site |
probably benign |
|
|
R0332:Aox3
|
UTSW |
1 |
58,181,910 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0626:Aox3
|
UTSW |
1 |
58,211,458 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1325:Aox3
|
UTSW |
1 |
58,215,726 (GRCm39) |
nonsense |
probably null |
|
|
R1435:Aox3
|
UTSW |
1 |
58,202,605 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1438:Aox3
|
UTSW |
1 |
58,192,337 (GRCm39) |
missense |
probably benign |
|
|
R1567:Aox3
|
UTSW |
1 |
58,233,852 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1575:Aox3
|
UTSW |
1 |
58,191,713 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1759:Aox3
|
UTSW |
1 |
58,209,805 (GRCm39) |
splice site |
probably null |
|
|
R1785:Aox3
|
UTSW |
1 |
58,209,002 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1786:Aox3
|
UTSW |
1 |
58,209,002 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1921:Aox3
|
UTSW |
1 |
58,219,810 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1984:Aox3
|
UTSW |
1 |
58,192,220 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R2012:Aox3
|
UTSW |
1 |
58,177,391 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2080:Aox3
|
UTSW |
1 |
58,225,439 (GRCm39) |
missense |
probably benign |
0.06 |
|
R2121:Aox3
|
UTSW |
1 |
58,191,708 (GRCm39) |
splice site |
probably benign |
|
|
R2126:Aox3
|
UTSW |
1 |
58,197,375 (GRCm39) |
missense |
probably benign |
0.25 |
|
R2130:Aox3
|
UTSW |
1 |
58,209,002 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2131:Aox3
|
UTSW |
1 |
58,209,002 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2132:Aox3
|
UTSW |
1 |
58,209,002 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2133:Aox3
|
UTSW |
1 |
58,209,002 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2385:Aox3
|
UTSW |
1 |
58,177,448 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2495:Aox3
|
UTSW |
1 |
58,227,567 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4200:Aox3
|
UTSW |
1 |
58,227,537 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4231:Aox3
|
UTSW |
1 |
58,154,044 (GRCm39) |
missense |
probably benign |
0.12 |
|
R4591:Aox3
|
UTSW |
1 |
58,191,815 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4627:Aox3
|
UTSW |
1 |
58,164,194 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4831:Aox3
|
UTSW |
1 |
58,191,725 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R4864:Aox3
|
UTSW |
1 |
58,215,646 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4976:Aox3
|
UTSW |
1 |
58,227,683 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5007:Aox3
|
UTSW |
1 |
58,202,583 (GRCm39) |
missense |
probably benign |
|
|
R5119:Aox3
|
UTSW |
1 |
58,227,683 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5175:Aox3
|
UTSW |
1 |
58,211,487 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5360:Aox3
|
UTSW |
1 |
58,185,667 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5784:Aox3
|
UTSW |
1 |
58,192,658 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6050:Aox3
|
UTSW |
1 |
58,219,814 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R6056:Aox3
|
UTSW |
1 |
58,209,018 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6162:Aox3
|
UTSW |
1 |
58,198,890 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R6181:Aox3
|
UTSW |
1 |
58,198,105 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6374:Aox3
|
UTSW |
1 |
58,211,320 (GRCm39) |
missense |
probably benign |
0.11 |
|
R6662:Aox3
|
UTSW |
1 |
58,157,774 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6809:Aox3
|
UTSW |
1 |
58,157,840 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6810:Aox3
|
UTSW |
1 |
58,180,590 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6821:Aox3
|
UTSW |
1 |
58,189,547 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7039:Aox3
|
UTSW |
1 |
58,215,714 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7116:Aox3
|
UTSW |
1 |
58,192,689 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7146:Aox3
|
UTSW |
1 |
58,197,688 (GRCm39) |
splice site |
probably null |
|
|
R7163:Aox3
|
UTSW |
1 |
58,158,671 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7243:Aox3
|
UTSW |
1 |
58,177,466 (GRCm39) |
missense |
unknown |
|
|
R7319:Aox3
|
UTSW |
1 |
58,191,761 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7423:Aox3
|
UTSW |
1 |
58,160,228 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R7664:Aox3
|
UTSW |
1 |
58,158,698 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7709:Aox3
|
UTSW |
1 |
58,219,810 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7745:Aox3
|
UTSW |
1 |
58,215,676 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R7751:Aox3
|
UTSW |
1 |
58,218,494 (GRCm39) |
missense |
probably benign |
0.11 |
|
R7940:Aox3
|
UTSW |
1 |
58,227,596 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8143:Aox3
|
UTSW |
1 |
58,198,074 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8178:Aox3
|
UTSW |
1 |
58,189,481 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R8719:Aox3
|
UTSW |
1 |
58,158,696 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8861:Aox3
|
UTSW |
1 |
58,189,460 (GRCm39) |
missense |
probably benign |
|
|
R9379:Aox3
|
UTSW |
1 |
58,208,959 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R9459:Aox3
|
UTSW |
1 |
58,189,468 (GRCm39) |
missense |
probably benign |
0.10 |
|
R9472:Aox3
|
UTSW |
1 |
58,215,669 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R9479:Aox3
|
UTSW |
1 |
58,177,568 (GRCm39) |
missense |
probably benign |
0.23 |
|
R9521:Aox3
|
UTSW |
1 |
58,164,222 (GRCm39) |
missense |
probably benign |
0.10 |
|
R9750:Aox3
|
UTSW |
1 |
58,215,648 (GRCm39) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TACAACTCTCAATCTGATGCTGTATCC -3'
(R):5'- GATCAGCCACAGTTCAGCAC -3'
Sequencing Primer
(F):5'- AATCTGATGCTGTATCCTCCGTC -3'
(R):5'- CACTGGCTGAGTGTGATCTCC -3'
|
| Posted On |
2019-12-20 |
Incidental Mutation