Incidental Mutation 'R0685:Psme4'
| ID |
61133 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Psme4
|
| Ensembl Gene |
ENSMUSG00000040850 |
| Gene Name |
proteasome (prosome, macropain) activator subunit 4 |
| Synonyms |
|
| MMRRC Submission |
038870-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R0685 (G1)
|
| Quality Score |
142 |
|
Status
|
Validated
|
| Chromosome |
11 |
| Chromosomal Location |
30721726-30830361 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 30828415 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Alanine
at position 1812
(T1812A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000045460
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000041231]
|
| AlphaFold |
Q5SSW2 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000041231
AA Change: T1812A
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000045460
Gene: ENSMUSG00000040850
AA Change: T1812A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
19 |
N/A |
INTRINSIC |
|
low complexity region
|
122 |
133 |
N/A |
INTRINSIC |
|
Pfam:BLM10_mid
|
330 |
828 |
8.8e-119 |
PFAM |
|
SCOP:d1b3ua_
|
1183 |
1716 |
3e-14 |
SMART |
|
Pfam:DUF3437
|
1756 |
1843 |
5.3e-39 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000155719
|
| Meta Mutation Damage Score |
0.1931 |
| Coding Region Coverage |
- 1x: 99.4%
- 3x: 98.8%
- 10x: 97.6%
- 20x: 95.6%
|
| Validation Efficiency |
98% (89/91) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a knock-out allele show normal repair of DNA double-strand breaks but exhibit significantly reduced male fertility due to defects in spermatogenesis observed in both meiotic spermatocytes and postmeiotic haploid spermatids. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(25) : Targeted, knock-out(1) Gene trapped(24) |
| Other mutations in this stock |
Total: 80 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700020N01Rik |
A |
G |
10: 21,469,337 (GRCm39) |
D17G |
probably damaging |
Het |
| Abi3bp |
A |
G |
16: 56,353,316 (GRCm39) |
T82A |
possibly damaging |
Het |
| Adgre4 |
A |
C |
17: 56,099,035 (GRCm39) |
E180D |
probably benign |
Het |
| Ankrd28 |
G |
A |
14: 31,465,407 (GRCm39) |
|
probably benign |
Het |
| Aoc3 |
A |
G |
11: 101,227,273 (GRCm39) |
D382G |
possibly damaging |
Het |
| Apob |
C |
A |
12: 8,060,742 (GRCm39) |
R3075S |
probably benign |
Het |
| Aqr |
A |
G |
2: 113,971,458 (GRCm39) |
F459S |
probably damaging |
Het |
| Bcr |
T |
C |
10: 74,967,475 (GRCm39) |
W570R |
probably damaging |
Het |
| Bloc1s5 |
C |
T |
13: 38,787,895 (GRCm39) |
R163K |
probably benign |
Het |
| Bod1 |
A |
T |
11: 31,619,267 (GRCm39) |
N101K |
possibly damaging |
Het |
| Bysl |
A |
T |
17: 47,913,396 (GRCm39) |
S296T |
probably benign |
Het |
| Chl1 |
G |
A |
6: 103,685,503 (GRCm39) |
|
probably null |
Het |
| Clstn1 |
G |
A |
4: 149,731,312 (GRCm39) |
A885T |
probably benign |
Het |
| Cyp3a25 |
G |
T |
5: 145,935,356 (GRCm39) |
P87T |
probably damaging |
Het |
| Dync1h1 |
T |
C |
12: 110,623,626 (GRCm39) |
V3633A |
probably damaging |
Het |
| Dynlt5 |
T |
C |
4: 102,859,735 (GRCm39) |
Y96H |
probably damaging |
Het |
| Elp4 |
C |
A |
2: 105,622,622 (GRCm39) |
C241F |
possibly damaging |
Het |
| Fat4 |
T |
A |
3: 39,055,327 (GRCm39) |
F4182Y |
probably benign |
Het |
| Gabbr2 |
G |
A |
4: 46,787,521 (GRCm39) |
H381Y |
possibly damaging |
Het |
| Gm10577 |
G |
T |
4: 100,877,515 (GRCm39) |
|
probably benign |
Het |
| Gm9955 |
G |
T |
18: 24,842,314 (GRCm39) |
|
probably benign |
Het |
| Gstm5 |
T |
A |
3: 107,804,635 (GRCm39) |
I73N |
probably damaging |
Het |
| Gypa |
T |
A |
8: 81,223,331 (GRCm39) |
|
probably benign |
Het |
| Hectd2 |
T |
A |
19: 36,546,831 (GRCm39) |
V64D |
probably damaging |
Het |
| Igkv10-95 |
T |
A |
6: 68,657,543 (GRCm39) |
Y20N |
probably benign |
Het |
| Il15 |
T |
C |
8: 83,064,188 (GRCm39) |
|
probably benign |
Het |
| Iqca1 |
C |
A |
1: 90,070,453 (GRCm39) |
G133V |
probably null |
Het |
| Kiz |
C |
A |
2: 146,697,978 (GRCm39) |
|
probably benign |
Het |
| Lcmt2 |
C |
A |
2: 120,969,721 (GRCm39) |
S234I |
probably benign |
Het |
| Lilra5 |
A |
G |
7: 4,244,956 (GRCm39) |
|
probably benign |
Het |
| Lin37 |
T |
C |
7: 30,255,299 (GRCm39) |
E187G |
probably damaging |
Het |
| Lrrc37 |
T |
C |
11: 103,507,714 (GRCm39) |
|
probably benign |
Het |
| Mcmdc2 |
T |
A |
1: 9,982,039 (GRCm39) |
|
probably null |
Het |
| Mctp1 |
T |
C |
13: 76,973,918 (GRCm39) |
|
probably null |
Het |
| Mdp1 |
C |
A |
14: 55,896,726 (GRCm39) |
G112* |
probably null |
Het |
| Mmp15 |
T |
C |
8: 96,098,762 (GRCm39) |
Y530H |
possibly damaging |
Het |
| Mtss2 |
T |
C |
8: 111,454,029 (GRCm39) |
|
probably null |
Het |
| Muc5ac |
T |
C |
7: 141,361,446 (GRCm39) |
S1586P |
probably benign |
Het |
| Nap1l5 |
A |
T |
6: 58,883,757 (GRCm39) |
C66S |
possibly damaging |
Het |
| Ninl |
G |
T |
2: 150,781,775 (GRCm39) |
Q1237K |
possibly damaging |
Het |
| Or5p70 |
A |
T |
7: 107,994,470 (GRCm39) |
T48S |
possibly damaging |
Het |
| Or9m1b |
T |
C |
2: 87,836,762 (GRCm39) |
E111G |
probably damaging |
Het |
| Orc6 |
T |
G |
8: 86,027,783 (GRCm39) |
S37R |
possibly damaging |
Het |
| Papss1 |
A |
C |
3: 131,288,854 (GRCm39) |
N119H |
possibly damaging |
Het |
| Phf13 |
A |
T |
4: 152,076,069 (GRCm39) |
F278I |
probably damaging |
Het |
| Pole2 |
C |
A |
12: 69,258,187 (GRCm39) |
A239S |
probably damaging |
Het |
| Ppt2 |
T |
C |
17: 34,845,546 (GRCm39) |
D75G |
probably damaging |
Het |
| Psd2 |
A |
G |
18: 36,136,044 (GRCm39) |
D443G |
possibly damaging |
Het |
| Psen1 |
C |
A |
12: 83,761,594 (GRCm39) |
S132* |
probably null |
Het |
| Rasgrf1 |
T |
C |
9: 89,797,535 (GRCm39) |
|
probably benign |
Het |
| Reep3 |
A |
G |
10: 66,857,518 (GRCm39) |
|
probably benign |
Het |
| Rexo4 |
A |
T |
2: 26,848,586 (GRCm39) |
|
probably benign |
Het |
| Rnf6 |
A |
C |
5: 146,148,468 (GRCm39) |
S183R |
probably damaging |
Het |
| Scai |
A |
T |
2: 38,993,749 (GRCm39) |
M297K |
probably damaging |
Het |
| Scn9a |
A |
T |
2: 66,313,843 (GRCm39) |
S1947R |
probably benign |
Het |
| Sema6c |
T |
C |
3: 95,080,021 (GRCm39) |
C772R |
possibly damaging |
Het |
| Skint7 |
T |
C |
4: 111,837,542 (GRCm39) |
S107P |
possibly damaging |
Het |
| Slc24a3 |
A |
G |
2: 145,448,715 (GRCm39) |
N420D |
probably benign |
Het |
| Smc1b |
T |
C |
15: 84,955,021 (GRCm39) |
D1077G |
possibly damaging |
Het |
| Smg7 |
G |
A |
1: 152,742,399 (GRCm39) |
P82L |
probably damaging |
Het |
| Sp3 |
A |
C |
2: 72,801,342 (GRCm39) |
F268V |
probably damaging |
Het |
| Srms |
T |
C |
2: 180,854,426 (GRCm39) |
D47G |
probably benign |
Het |
| Ss18 |
A |
C |
18: 14,784,238 (GRCm39) |
M150R |
probably damaging |
Het |
| Taf5 |
G |
A |
19: 47,063,293 (GRCm39) |
R281Q |
probably benign |
Het |
| Tars1 |
T |
C |
15: 11,385,259 (GRCm39) |
K644R |
probably benign |
Het |
| Tinag |
C |
A |
9: 76,859,285 (GRCm39) |
W441L |
probably damaging |
Het |
| Tmtc1 |
T |
C |
6: 148,312,738 (GRCm39) |
S244G |
probably benign |
Het |
| Tpr |
T |
C |
1: 150,309,476 (GRCm39) |
V1670A |
possibly damaging |
Het |
| Trpv3 |
A |
G |
11: 73,187,640 (GRCm39) |
|
probably benign |
Het |
| Uhrf1 |
G |
T |
17: 56,617,742 (GRCm39) |
V155L |
probably damaging |
Het |
| Ush2a |
G |
A |
1: 188,132,475 (GRCm39) |
C899Y |
probably damaging |
Het |
| Vmn2r115 |
G |
A |
17: 23,578,249 (GRCm39) |
R574H |
probably benign |
Het |
| Vmn2r63 |
T |
C |
7: 42,577,434 (GRCm39) |
D368G |
probably benign |
Het |
| Vps13a |
A |
G |
19: 16,758,105 (GRCm39) |
V10A |
probably damaging |
Het |
| Wbp11 |
A |
G |
6: 136,791,636 (GRCm39) |
|
probably benign |
Het |
| Zcwpw1 |
A |
G |
5: 137,797,854 (GRCm39) |
D145G |
probably benign |
Het |
| Zfp607a |
G |
A |
7: 27,577,901 (GRCm39) |
V324I |
probably damaging |
Het |
| Zfp618 |
A |
G |
4: 63,052,011 (GRCm39) |
I931V |
probably benign |
Het |
| Zfp821 |
T |
C |
8: 110,451,174 (GRCm39) |
V389A |
possibly damaging |
Het |
| Zfp976 |
T |
A |
7: 42,263,141 (GRCm39) |
H232L |
probably damaging |
Het |
|
| Other mutations in Psme4 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00228:Psme4
|
APN |
11 |
30,765,710 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL00401:Psme4
|
APN |
11 |
30,771,079 (GRCm39) |
splice site |
probably benign |
|
|
IGL00475:Psme4
|
APN |
11 |
30,795,252 (GRCm39) |
missense |
probably benign |
0.14 |
|
IGL00576:Psme4
|
APN |
11 |
30,773,145 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
IGL00817:Psme4
|
APN |
11 |
30,770,129 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01525:Psme4
|
APN |
11 |
30,759,936 (GRCm39) |
splice site |
probably benign |
|
|
IGL01862:Psme4
|
APN |
11 |
30,762,038 (GRCm39) |
nonsense |
probably null |
|
|
IGL02310:Psme4
|
APN |
11 |
30,787,484 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL02477:Psme4
|
APN |
11 |
30,792,083 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02545:Psme4
|
APN |
11 |
30,791,586 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
IGL02608:Psme4
|
APN |
11 |
30,770,944 (GRCm39) |
missense |
probably benign |
0.34 |
|
IGL02621:Psme4
|
APN |
11 |
30,798,131 (GRCm39) |
missense |
probably benign |
|
|
IGL02822:Psme4
|
APN |
11 |
30,798,204 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02833:Psme4
|
APN |
11 |
30,800,715 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02964:Psme4
|
APN |
11 |
30,741,095 (GRCm39) |
nonsense |
probably null |
|
|
IGL03273:Psme4
|
APN |
11 |
30,798,130 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03348:Psme4
|
APN |
11 |
30,826,796 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03382:Psme4
|
APN |
11 |
30,757,788 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
H2330:Psme4
|
UTSW |
11 |
30,801,210 (GRCm39) |
missense |
probably benign |
0.17 |
|
PIT4378001:Psme4
|
UTSW |
11 |
30,771,079 (GRCm39) |
splice site |
probably benign |
|
|
R0276:Psme4
|
UTSW |
11 |
30,761,980 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0462:Psme4
|
UTSW |
11 |
30,798,117 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0766:Psme4
|
UTSW |
11 |
30,757,687 (GRCm39) |
splice site |
probably null |
|
|
R0830:Psme4
|
UTSW |
11 |
30,757,797 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R0940:Psme4
|
UTSW |
11 |
30,765,264 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R1018:Psme4
|
UTSW |
11 |
30,754,310 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1312:Psme4
|
UTSW |
11 |
30,757,687 (GRCm39) |
splice site |
probably null |
|
|
R1448:Psme4
|
UTSW |
11 |
30,802,744 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1713:Psme4
|
UTSW |
11 |
30,756,310 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1732:Psme4
|
UTSW |
11 |
30,798,105 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1813:Psme4
|
UTSW |
11 |
30,754,353 (GRCm39) |
missense |
probably benign |
0.14 |
|
R1905:Psme4
|
UTSW |
11 |
30,760,922 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1907:Psme4
|
UTSW |
11 |
30,760,922 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1911:Psme4
|
UTSW |
11 |
30,765,658 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1956:Psme4
|
UTSW |
11 |
30,782,424 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1974:Psme4
|
UTSW |
11 |
30,769,011 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1980:Psme4
|
UTSW |
11 |
30,782,615 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R1986:Psme4
|
UTSW |
11 |
30,780,352 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2046:Psme4
|
UTSW |
11 |
30,767,723 (GRCm39) |
splice site |
probably benign |
|
|
R2142:Psme4
|
UTSW |
11 |
30,770,998 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R2698:Psme4
|
UTSW |
11 |
30,824,282 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2844:Psme4
|
UTSW |
11 |
30,795,173 (GRCm39) |
splice site |
probably benign |
|
|
R3807:Psme4
|
UTSW |
11 |
30,806,027 (GRCm39) |
splice site |
probably null |
|
|
R3876:Psme4
|
UTSW |
11 |
30,806,068 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4420:Psme4
|
UTSW |
11 |
30,762,028 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R4584:Psme4
|
UTSW |
11 |
30,784,318 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4615:Psme4
|
UTSW |
11 |
30,784,287 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4714:Psme4
|
UTSW |
11 |
30,782,573 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5008:Psme4
|
UTSW |
11 |
30,806,896 (GRCm39) |
intron |
probably benign |
|
|
R5109:Psme4
|
UTSW |
11 |
30,741,095 (GRCm39) |
nonsense |
probably null |
|
|
R5155:Psme4
|
UTSW |
11 |
30,826,806 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5199:Psme4
|
UTSW |
11 |
30,803,272 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5205:Psme4
|
UTSW |
11 |
30,782,666 (GRCm39) |
intron |
probably benign |
|
|
R5452:Psme4
|
UTSW |
11 |
30,741,168 (GRCm39) |
missense |
probably benign |
|
|
R5491:Psme4
|
UTSW |
11 |
30,765,246 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R5685:Psme4
|
UTSW |
11 |
30,759,837 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5764:Psme4
|
UTSW |
11 |
30,722,364 (GRCm39) |
intron |
probably benign |
|
|
R5853:Psme4
|
UTSW |
11 |
30,741,234 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5865:Psme4
|
UTSW |
11 |
30,741,993 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5903:Psme4
|
UTSW |
11 |
30,791,589 (GRCm39) |
missense |
probably benign |
0.28 |
|
R5927:Psme4
|
UTSW |
11 |
30,754,294 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R6004:Psme4
|
UTSW |
11 |
30,806,896 (GRCm39) |
intron |
probably benign |
|
|
R6102:Psme4
|
UTSW |
11 |
30,815,567 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6247:Psme4
|
UTSW |
11 |
30,803,245 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R6527:Psme4
|
UTSW |
11 |
30,782,175 (GRCm39) |
missense |
probably benign |
|
|
R6750:Psme4
|
UTSW |
11 |
30,803,203 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6885:Psme4
|
UTSW |
11 |
30,784,307 (GRCm39) |
nonsense |
probably null |
|
|
R6939:Psme4
|
UTSW |
11 |
30,787,291 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6945:Psme4
|
UTSW |
11 |
30,787,437 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7029:Psme4
|
UTSW |
11 |
30,722,474 (GRCm39) |
intron |
probably benign |
|
|
R7049:Psme4
|
UTSW |
11 |
30,763,904 (GRCm39) |
splice site |
probably null |
|
|
R7098:Psme4
|
UTSW |
11 |
30,800,661 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7107:Psme4
|
UTSW |
11 |
30,798,105 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7223:Psme4
|
UTSW |
11 |
30,824,226 (GRCm39) |
missense |
probably benign |
0.33 |
|
R7319:Psme4
|
UTSW |
11 |
30,757,790 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7375:Psme4
|
UTSW |
11 |
30,722,700 (GRCm39) |
splice site |
probably null |
|
|
R7410:Psme4
|
UTSW |
11 |
30,765,279 (GRCm39) |
nonsense |
probably null |
|
|
R7469:Psme4
|
UTSW |
11 |
30,752,837 (GRCm39) |
missense |
probably benign |
0.20 |
|
R7651:Psme4
|
UTSW |
11 |
30,787,334 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7679:Psme4
|
UTSW |
11 |
30,828,425 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7681:Psme4
|
UTSW |
11 |
30,741,975 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R7822:Psme4
|
UTSW |
11 |
30,824,245 (GRCm39) |
missense |
probably benign |
|
|
R8013:Psme4
|
UTSW |
11 |
30,754,320 (GRCm39) |
missense |
probably benign |
0.06 |
|
R8130:Psme4
|
UTSW |
11 |
30,792,026 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8323:Psme4
|
UTSW |
11 |
30,793,532 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8330:Psme4
|
UTSW |
11 |
30,793,583 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8363:Psme4
|
UTSW |
11 |
30,762,139 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8491:Psme4
|
UTSW |
11 |
30,722,161 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8690:Psme4
|
UTSW |
11 |
30,787,319 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8696:Psme4
|
UTSW |
11 |
30,759,896 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8743:Psme4
|
UTSW |
11 |
30,828,467 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8998:Psme4
|
UTSW |
11 |
30,788,957 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R9241:Psme4
|
UTSW |
11 |
30,815,576 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9657:Psme4
|
UTSW |
11 |
30,788,980 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9736:Psme4
|
UTSW |
11 |
30,797,411 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9744:Psme4
|
UTSW |
11 |
30,765,294 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9746:Psme4
|
UTSW |
11 |
30,826,868 (GRCm39) |
nonsense |
probably null |
|
|
V5088:Psme4
|
UTSW |
11 |
30,801,210 (GRCm39) |
missense |
probably benign |
0.17 |
|
X0063:Psme4
|
UTSW |
11 |
30,782,600 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
Z1176:Psme4
|
UTSW |
11 |
30,793,522 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
Z1177:Psme4
|
UTSW |
11 |
30,762,138 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Psme4
|
UTSW |
11 |
30,756,311 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- CGCAAAACAGGTCACCTTCGTAGATG -3'
(R):5'- CAGCACTGGAAATCGAATTAGGGTCTC -3'
Sequencing Primer
(F):5'- atatTGAACTGGTCTAGCAATGTGAC -3'
(R):5'- ctcttcctctaaactatctacccc -3'
|
| Posted On |
2013-07-30 |
Incidental Mutation