Incidental Mutation 'R0685:Abi3bp'
| ID |
61145 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Abi3bp
|
| Ensembl Gene |
ENSMUSG00000035258 |
| Gene Name |
ABI family member 3 binding protein |
| Synonyms |
D930038M13Rik, TARSH, 5033411B22Rik, eratin |
| MMRRC Submission |
038870-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.090)
|
| Stock # |
R0685 (G1)
|
| Quality Score |
120 |
|
Status
|
Validated
|
| Chromosome |
16 |
| Chromosomal Location |
56298241-56510498 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 56353316 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Alanine
at position 82
(T82A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000036257
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000048471]
[ENSMUST00000096012]
[ENSMUST00000096013]
[ENSMUST00000171000]
[ENSMUST00000231781]
[ENSMUST00000231832]
[ENSMUST00000231870]
|
| AlphaFold |
A0A338P6S8 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000048471
AA Change: T82A
PolyPhen 2
Score 0.902 (Sensitivity: 0.82; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000036257
Gene: ENSMUSG00000035258
AA Change: T82A
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
21 |
N/A |
INTRINSIC |
|
FN3
|
114 |
203 |
3.08e-2 |
SMART |
|
low complexity region
|
433 |
446 |
N/A |
INTRINSIC |
|
low complexity region
|
516 |
528 |
N/A |
INTRINSIC |
|
low complexity region
|
579 |
591 |
N/A |
INTRINSIC |
|
low complexity region
|
734 |
747 |
N/A |
INTRINSIC |
|
low complexity region
|
751 |
764 |
N/A |
INTRINSIC |
|
FN3
|
941 |
1024 |
6.29e-8 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000096012
AA Change: T82A
PolyPhen 2
Score 0.803 (Sensitivity: 0.84; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000093711
Gene: ENSMUSG00000035258
AA Change: T82A
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
21 |
N/A |
INTRINSIC |
|
FN3
|
114 |
203 |
3.08e-2 |
SMART |
|
low complexity region
|
433 |
446 |
N/A |
INTRINSIC |
|
low complexity region
|
634 |
647 |
N/A |
INTRINSIC |
|
low complexity region
|
651 |
664 |
N/A |
INTRINSIC |
|
FN3
|
841 |
924 |
6.29e-8 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000096013
AA Change: T82A
PolyPhen 2
Score 0.650 (Sensitivity: 0.87; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000093712
Gene: ENSMUSG00000035258
AA Change: T82A
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
21 |
N/A |
INTRINSIC |
|
FN3
|
114 |
203 |
3.08e-2 |
SMART |
|
low complexity region
|
433 |
446 |
N/A |
INTRINSIC |
|
low complexity region
|
670 |
683 |
N/A |
INTRINSIC |
|
low complexity region
|
687 |
700 |
N/A |
INTRINSIC |
|
FN3
|
877 |
960 |
6.29e-8 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000171000
AA Change: T82A
PolyPhen 2
Score 0.235 (Sensitivity: 0.91; Specificity: 0.88)
|
| SMART Domains |
Protein: ENSMUSP00000128818
Gene: ENSMUSG00000035258
AA Change: T82A
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
21 |
N/A |
INTRINSIC |
|
FN3
|
114 |
203 |
3.08e-2 |
SMART |
|
low complexity region
|
464 |
477 |
N/A |
INTRINSIC |
|
low complexity region
|
481 |
494 |
N/A |
INTRINSIC |
|
FN3
|
671 |
754 |
6.29e-8 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000231337
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000231781
AA Change: T82A
PolyPhen 2
Score 0.862 (Sensitivity: 0.83; Specificity: 0.93)
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000231832
AA Change: T82A
PolyPhen 2
Score 0.760 (Sensitivity: 0.85; Specificity: 0.92)
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000231870
AA Change: T82A
PolyPhen 2
Score 0.763 (Sensitivity: 0.85; Specificity: 0.92)
|
| Meta Mutation Damage Score |
0.1131 |
| Coding Region Coverage |
- 1x: 99.4%
- 3x: 98.8%
- 10x: 97.6%
- 20x: 95.6%
|
| Validation Efficiency |
98% (89/91) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 80 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700020N01Rik |
A |
G |
10: 21,469,337 (GRCm39) |
D17G |
probably damaging |
Het |
| Adgre4 |
A |
C |
17: 56,099,035 (GRCm39) |
E180D |
probably benign |
Het |
| Ankrd28 |
G |
A |
14: 31,465,407 (GRCm39) |
|
probably benign |
Het |
| Aoc3 |
A |
G |
11: 101,227,273 (GRCm39) |
D382G |
possibly damaging |
Het |
| Apob |
C |
A |
12: 8,060,742 (GRCm39) |
R3075S |
probably benign |
Het |
| Aqr |
A |
G |
2: 113,971,458 (GRCm39) |
F459S |
probably damaging |
Het |
| Bcr |
T |
C |
10: 74,967,475 (GRCm39) |
W570R |
probably damaging |
Het |
| Bloc1s5 |
C |
T |
13: 38,787,895 (GRCm39) |
R163K |
probably benign |
Het |
| Bod1 |
A |
T |
11: 31,619,267 (GRCm39) |
N101K |
possibly damaging |
Het |
| Bysl |
A |
T |
17: 47,913,396 (GRCm39) |
S296T |
probably benign |
Het |
| Chl1 |
G |
A |
6: 103,685,503 (GRCm39) |
|
probably null |
Het |
| Clstn1 |
G |
A |
4: 149,731,312 (GRCm39) |
A885T |
probably benign |
Het |
| Cyp3a25 |
G |
T |
5: 145,935,356 (GRCm39) |
P87T |
probably damaging |
Het |
| Dync1h1 |
T |
C |
12: 110,623,626 (GRCm39) |
V3633A |
probably damaging |
Het |
| Dynlt5 |
T |
C |
4: 102,859,735 (GRCm39) |
Y96H |
probably damaging |
Het |
| Elp4 |
C |
A |
2: 105,622,622 (GRCm39) |
C241F |
possibly damaging |
Het |
| Fat4 |
T |
A |
3: 39,055,327 (GRCm39) |
F4182Y |
probably benign |
Het |
| Gabbr2 |
G |
A |
4: 46,787,521 (GRCm39) |
H381Y |
possibly damaging |
Het |
| Gm10577 |
G |
T |
4: 100,877,515 (GRCm39) |
|
probably benign |
Het |
| Gm9955 |
G |
T |
18: 24,842,314 (GRCm39) |
|
probably benign |
Het |
| Gstm5 |
T |
A |
3: 107,804,635 (GRCm39) |
I73N |
probably damaging |
Het |
| Gypa |
T |
A |
8: 81,223,331 (GRCm39) |
|
probably benign |
Het |
| Hectd2 |
T |
A |
19: 36,546,831 (GRCm39) |
V64D |
probably damaging |
Het |
| Igkv10-95 |
T |
A |
6: 68,657,543 (GRCm39) |
Y20N |
probably benign |
Het |
| Il15 |
T |
C |
8: 83,064,188 (GRCm39) |
|
probably benign |
Het |
| Iqca1 |
C |
A |
1: 90,070,453 (GRCm39) |
G133V |
probably null |
Het |
| Kiz |
C |
A |
2: 146,697,978 (GRCm39) |
|
probably benign |
Het |
| Lcmt2 |
C |
A |
2: 120,969,721 (GRCm39) |
S234I |
probably benign |
Het |
| Lilra5 |
A |
G |
7: 4,244,956 (GRCm39) |
|
probably benign |
Het |
| Lin37 |
T |
C |
7: 30,255,299 (GRCm39) |
E187G |
probably damaging |
Het |
| Lrrc37 |
T |
C |
11: 103,507,714 (GRCm39) |
|
probably benign |
Het |
| Mcmdc2 |
T |
A |
1: 9,982,039 (GRCm39) |
|
probably null |
Het |
| Mctp1 |
T |
C |
13: 76,973,918 (GRCm39) |
|
probably null |
Het |
| Mdp1 |
C |
A |
14: 55,896,726 (GRCm39) |
G112* |
probably null |
Het |
| Mmp15 |
T |
C |
8: 96,098,762 (GRCm39) |
Y530H |
possibly damaging |
Het |
| Mtss2 |
T |
C |
8: 111,454,029 (GRCm39) |
|
probably null |
Het |
| Muc5ac |
T |
C |
7: 141,361,446 (GRCm39) |
S1586P |
probably benign |
Het |
| Nap1l5 |
A |
T |
6: 58,883,757 (GRCm39) |
C66S |
possibly damaging |
Het |
| Ninl |
G |
T |
2: 150,781,775 (GRCm39) |
Q1237K |
possibly damaging |
Het |
| Or5p70 |
A |
T |
7: 107,994,470 (GRCm39) |
T48S |
possibly damaging |
Het |
| Or9m1b |
T |
C |
2: 87,836,762 (GRCm39) |
E111G |
probably damaging |
Het |
| Orc6 |
T |
G |
8: 86,027,783 (GRCm39) |
S37R |
possibly damaging |
Het |
| Papss1 |
A |
C |
3: 131,288,854 (GRCm39) |
N119H |
possibly damaging |
Het |
| Phf13 |
A |
T |
4: 152,076,069 (GRCm39) |
F278I |
probably damaging |
Het |
| Pole2 |
C |
A |
12: 69,258,187 (GRCm39) |
A239S |
probably damaging |
Het |
| Ppt2 |
T |
C |
17: 34,845,546 (GRCm39) |
D75G |
probably damaging |
Het |
| Psd2 |
A |
G |
18: 36,136,044 (GRCm39) |
D443G |
possibly damaging |
Het |
| Psen1 |
C |
A |
12: 83,761,594 (GRCm39) |
S132* |
probably null |
Het |
| Psme4 |
A |
G |
11: 30,828,415 (GRCm39) |
T1812A |
probably damaging |
Het |
| Rasgrf1 |
T |
C |
9: 89,797,535 (GRCm39) |
|
probably benign |
Het |
| Reep3 |
A |
G |
10: 66,857,518 (GRCm39) |
|
probably benign |
Het |
| Rexo4 |
A |
T |
2: 26,848,586 (GRCm39) |
|
probably benign |
Het |
| Rnf6 |
A |
C |
5: 146,148,468 (GRCm39) |
S183R |
probably damaging |
Het |
| Scai |
A |
T |
2: 38,993,749 (GRCm39) |
M297K |
probably damaging |
Het |
| Scn9a |
A |
T |
2: 66,313,843 (GRCm39) |
S1947R |
probably benign |
Het |
| Sema6c |
T |
C |
3: 95,080,021 (GRCm39) |
C772R |
possibly damaging |
Het |
| Skint7 |
T |
C |
4: 111,837,542 (GRCm39) |
S107P |
possibly damaging |
Het |
| Slc24a3 |
A |
G |
2: 145,448,715 (GRCm39) |
N420D |
probably benign |
Het |
| Smc1b |
T |
C |
15: 84,955,021 (GRCm39) |
D1077G |
possibly damaging |
Het |
| Smg7 |
G |
A |
1: 152,742,399 (GRCm39) |
P82L |
probably damaging |
Het |
| Sp3 |
A |
C |
2: 72,801,342 (GRCm39) |
F268V |
probably damaging |
Het |
| Srms |
T |
C |
2: 180,854,426 (GRCm39) |
D47G |
probably benign |
Het |
| Ss18 |
A |
C |
18: 14,784,238 (GRCm39) |
M150R |
probably damaging |
Het |
| Taf5 |
G |
A |
19: 47,063,293 (GRCm39) |
R281Q |
probably benign |
Het |
| Tars1 |
T |
C |
15: 11,385,259 (GRCm39) |
K644R |
probably benign |
Het |
| Tinag |
C |
A |
9: 76,859,285 (GRCm39) |
W441L |
probably damaging |
Het |
| Tmtc1 |
T |
C |
6: 148,312,738 (GRCm39) |
S244G |
probably benign |
Het |
| Tpr |
T |
C |
1: 150,309,476 (GRCm39) |
V1670A |
possibly damaging |
Het |
| Trpv3 |
A |
G |
11: 73,187,640 (GRCm39) |
|
probably benign |
Het |
| Uhrf1 |
G |
T |
17: 56,617,742 (GRCm39) |
V155L |
probably damaging |
Het |
| Ush2a |
G |
A |
1: 188,132,475 (GRCm39) |
C899Y |
probably damaging |
Het |
| Vmn2r115 |
G |
A |
17: 23,578,249 (GRCm39) |
R574H |
probably benign |
Het |
| Vmn2r63 |
T |
C |
7: 42,577,434 (GRCm39) |
D368G |
probably benign |
Het |
| Vps13a |
A |
G |
19: 16,758,105 (GRCm39) |
V10A |
probably damaging |
Het |
| Wbp11 |
A |
G |
6: 136,791,636 (GRCm39) |
|
probably benign |
Het |
| Zcwpw1 |
A |
G |
5: 137,797,854 (GRCm39) |
D145G |
probably benign |
Het |
| Zfp607a |
G |
A |
7: 27,577,901 (GRCm39) |
V324I |
probably damaging |
Het |
| Zfp618 |
A |
G |
4: 63,052,011 (GRCm39) |
I931V |
probably benign |
Het |
| Zfp821 |
T |
C |
8: 110,451,174 (GRCm39) |
V389A |
possibly damaging |
Het |
| Zfp976 |
T |
A |
7: 42,263,141 (GRCm39) |
H232L |
probably damaging |
Het |
|
| Other mutations in Abi3bp |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00780:Abi3bp
|
APN |
16 |
56,423,168 (GRCm39) |
missense |
probably null |
0.99 |
|
IGL01580:Abi3bp
|
APN |
16 |
56,495,573 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01633:Abi3bp
|
APN |
16 |
56,498,163 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01783:Abi3bp
|
APN |
16 |
56,353,332 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01866:Abi3bp
|
APN |
16 |
56,492,336 (GRCm39) |
missense |
probably benign |
0.19 |
|
IGL02022:Abi3bp
|
APN |
16 |
56,412,999 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02086:Abi3bp
|
APN |
16 |
56,462,930 (GRCm39) |
splice site |
probably benign |
|
|
IGL02122:Abi3bp
|
APN |
16 |
56,507,491 (GRCm39) |
splice site |
probably benign |
|
|
IGL02155:Abi3bp
|
APN |
16 |
56,408,327 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02351:Abi3bp
|
APN |
16 |
56,474,418 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL02358:Abi3bp
|
APN |
16 |
56,474,418 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL02418:Abi3bp
|
APN |
16 |
56,424,479 (GRCm39) |
splice site |
probably benign |
|
|
IGL02559:Abi3bp
|
APN |
16 |
56,507,433 (GRCm39) |
nonsense |
probably null |
|
|
IGL02617:Abi3bp
|
APN |
16 |
56,394,807 (GRCm39) |
nonsense |
probably null |
|
|
IGL02810:Abi3bp
|
APN |
16 |
56,498,138 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03057:Abi3bp
|
APN |
16 |
56,488,754 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL03174:Abi3bp
|
APN |
16 |
56,435,110 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R0389:Abi3bp
|
UTSW |
16 |
56,491,670 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R0485:Abi3bp
|
UTSW |
16 |
56,424,375 (GRCm39) |
splice site |
probably null |
|
|
R0557:Abi3bp
|
UTSW |
16 |
56,488,750 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0616:Abi3bp
|
UTSW |
16 |
56,474,433 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0783:Abi3bp
|
UTSW |
16 |
56,415,601 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R0828:Abi3bp
|
UTSW |
16 |
56,498,193 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0841:Abi3bp
|
UTSW |
16 |
56,488,639 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1078:Abi3bp
|
UTSW |
16 |
56,474,444 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1101:Abi3bp
|
UTSW |
16 |
56,426,521 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1116:Abi3bp
|
UTSW |
16 |
56,506,792 (GRCm39) |
splice site |
probably benign |
|
|
R1145:Abi3bp
|
UTSW |
16 |
56,488,639 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1145:Abi3bp
|
UTSW |
16 |
56,488,639 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1317:Abi3bp
|
UTSW |
16 |
56,488,672 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R1384:Abi3bp
|
UTSW |
16 |
56,394,862 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1460:Abi3bp
|
UTSW |
16 |
56,382,780 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1730:Abi3bp
|
UTSW |
16 |
56,488,642 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R1761:Abi3bp
|
UTSW |
16 |
56,488,672 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R1830:Abi3bp
|
UTSW |
16 |
56,408,348 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1873:Abi3bp
|
UTSW |
16 |
56,394,862 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1875:Abi3bp
|
UTSW |
16 |
56,394,862 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1996:Abi3bp
|
UTSW |
16 |
56,491,720 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R2018:Abi3bp
|
UTSW |
16 |
56,498,159 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2019:Abi3bp
|
UTSW |
16 |
56,498,159 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2035:Abi3bp
|
UTSW |
16 |
56,480,581 (GRCm39) |
missense |
probably benign |
0.21 |
|
R2118:Abi3bp
|
UTSW |
16 |
56,298,227 (GRCm39) |
unclassified |
probably benign |
|
|
R2202:Abi3bp
|
UTSW |
16 |
56,471,088 (GRCm39) |
nonsense |
probably null |
|
|
R2202:Abi3bp
|
UTSW |
16 |
56,433,566 (GRCm39) |
missense |
probably benign |
0.06 |
|
R2203:Abi3bp
|
UTSW |
16 |
56,433,566 (GRCm39) |
missense |
probably benign |
0.06 |
|
R3030:Abi3bp
|
UTSW |
16 |
56,477,682 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R3952:Abi3bp
|
UTSW |
16 |
56,424,401 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R4176:Abi3bp
|
UTSW |
16 |
56,472,563 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4296:Abi3bp
|
UTSW |
16 |
56,488,673 (GRCm39) |
missense |
probably benign |
0.05 |
|
R4301:Abi3bp
|
UTSW |
16 |
56,377,266 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4354:Abi3bp
|
UTSW |
16 |
56,353,314 (GRCm39) |
missense |
probably benign |
0.05 |
|
R4417:Abi3bp
|
UTSW |
16 |
56,474,398 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4716:Abi3bp
|
UTSW |
16 |
56,471,088 (GRCm39) |
nonsense |
probably null |
|
|
R4808:Abi3bp
|
UTSW |
16 |
56,414,879 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4814:Abi3bp
|
UTSW |
16 |
56,471,116 (GRCm39) |
missense |
probably benign |
0.06 |
|
R5016:Abi3bp
|
UTSW |
16 |
56,491,631 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5290:Abi3bp
|
UTSW |
16 |
56,462,838 (GRCm39) |
splice site |
probably null |
|
|
R5891:Abi3bp
|
UTSW |
16 |
56,426,496 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5897:Abi3bp
|
UTSW |
16 |
56,425,032 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R6146:Abi3bp
|
UTSW |
16 |
56,491,628 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6267:Abi3bp
|
UTSW |
16 |
56,414,860 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6905:Abi3bp
|
UTSW |
16 |
56,394,880 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6908:Abi3bp
|
UTSW |
16 |
56,477,668 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6917:Abi3bp
|
UTSW |
16 |
56,437,684 (GRCm39) |
splice site |
probably null |
|
|
R7071:Abi3bp
|
UTSW |
16 |
56,449,503 (GRCm39) |
nonsense |
probably null |
|
|
R7194:Abi3bp
|
UTSW |
16 |
56,382,734 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7476:Abi3bp
|
UTSW |
16 |
56,435,109 (GRCm39) |
nonsense |
probably null |
|
|
R7554:Abi3bp
|
UTSW |
16 |
56,438,575 (GRCm39) |
splice site |
probably null |
|
|
R7571:Abi3bp
|
UTSW |
16 |
56,451,345 (GRCm39) |
splice site |
probably null |
|
|
R7661:Abi3bp
|
UTSW |
16 |
56,453,263 (GRCm39) |
splice site |
probably null |
|
|
R7662:Abi3bp
|
UTSW |
16 |
56,437,686 (GRCm39) |
splice site |
probably null |
|
|
R7910:Abi3bp
|
UTSW |
16 |
56,498,105 (GRCm39) |
nonsense |
probably null |
|
|
R8121:Abi3bp
|
UTSW |
16 |
56,452,241 (GRCm39) |
missense |
unknown |
|
|
R8781:Abi3bp
|
UTSW |
16 |
56,426,512 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8790:Abi3bp
|
UTSW |
16 |
56,495,437 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8828:Abi3bp
|
UTSW |
16 |
56,507,455 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9094:Abi3bp
|
UTSW |
16 |
56,456,590 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9135:Abi3bp
|
UTSW |
16 |
56,417,173 (GRCm39) |
missense |
probably benign |
0.21 |
|
R9282:Abi3bp
|
UTSW |
16 |
56,440,867 (GRCm39) |
missense |
unknown |
|
|
R9363:Abi3bp
|
UTSW |
16 |
56,438,575 (GRCm39) |
splice site |
probably null |
|
|
R9464:Abi3bp
|
UTSW |
16 |
56,409,046 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R9506:Abi3bp
|
UTSW |
16 |
56,437,773 (GRCm39) |
missense |
unknown |
|
|
RF008:Abi3bp
|
UTSW |
16 |
56,447,952 (GRCm39) |
intron |
probably benign |
|
|
RF016:Abi3bp
|
UTSW |
16 |
56,447,950 (GRCm39) |
frame shift |
probably null |
|
|
RF052:Abi3bp
|
UTSW |
16 |
56,447,948 (GRCm39) |
intron |
probably benign |
|
|
RF061:Abi3bp
|
UTSW |
16 |
56,447,950 (GRCm39) |
frame shift |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- GAATGATGCTTCCAGCAAGCAAGG -3'
(R):5'- GCTCCAGGTTCCAGTTACAAAGGTG -3'
Sequencing Primer
(F):5'- GGTGAAATATCAGGCACTTACCTATG -3'
(R):5'- ACAAAGGTGATTTGTGTTGCCAC -3'
|
| Posted On |
2013-07-30 |
Incidental Mutation