|Institutional Source||Beutler Lab|
|Gene Name||Fc receptor, IgG, high affinity I|
|Is this an essential gene?||Possibly non essential (E-score: 0.449)|
|Stock #||R7939 (G1)|
|Chromosomal Location||96282909-96293969 bp(-) (GRCm38)|
|Type of Mutation||splice site|
|DNA Base Change (assembly)||A to T at 96284627 bp|
|Amino Acid Change|
|Ref Sequence||ENSEMBL: ENSMUSP00000029748 (fasta)|
|Gene Model||predicted gene model for transcript(s): [ENSMUST00000029748]|
|Predicted Effect||probably null
|Predicted Effect||probably benign
|Coding Region Coverage||
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein that plays an important role in the immune response. This protein is a high-affinity Fc-gamma receptor. The gene is one of three related gene family members located on chromosome 1. [provided by RefSeq, Jul 2008]
PHENOTYPE: Homozygous mutation of this gene results immune response defects including a decreased inflammatory response. [provided by MGI curators]
|Allele List at MGI|
|Other mutations in this stock||
|Other mutations in Fcgr1||
(F):5'- CGCTTCTAACTTGCTGAAAGG -3'
(R):5'- GGGTTCATAAGCCCAGAACC -3'
(F):5'- GCTGAAAGGAATTTGCTTTCTTTCC -3'
(R):5'- GACTCTGGCAGGGAAAAGTCCTC -3'