Incidental Mutation 'R0671:Abca17'
| ID |
61486 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Abca17
|
| Ensembl Gene |
ENSMUSG00000035435 |
| Gene Name |
ATP-binding cassette, sub-family A member 17 |
| Synonyms |
|
| MMRRC Submission |
038856-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R0671 (G1)
|
| Quality Score |
83 |
|
Status
|
Validated
|
| Chromosome |
17 |
| Chromosomal Location |
24483233-24570042 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 24500223 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Phenylalanine to Leucine
at position 1323
(F1323L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000112538
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000039324]
[ENSMUST00000121226]
|
| AlphaFold |
E9PX95 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000039324
AA Change: F1323L
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000046218
Gene: ENSMUSG00000035435
AA Change: F1323L
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
4 |
18 |
N/A |
INTRINSIC |
|
transmembrane domain
|
22 |
44 |
N/A |
INTRINSIC |
|
Pfam:ABC2_membrane_3
|
252 |
464 |
9.5e-17 |
PFAM |
|
AAA
|
547 |
729 |
5.71e-12 |
SMART |
|
low complexity region
|
846 |
857 |
N/A |
INTRINSIC |
|
Pfam:ABC2_membrane_3
|
905 |
1307 |
6.7e-35 |
PFAM |
|
low complexity region
|
1337 |
1351 |
N/A |
INTRINSIC |
|
AAA
|
1393 |
1577 |
1.15e-1 |
SMART |
|
low complexity region
|
1697 |
1730 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000121226
AA Change: F1323L
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000112538
Gene: ENSMUSG00000035435
AA Change: F1323L
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
4 |
18 |
N/A |
INTRINSIC |
|
Pfam:ABC2_membrane_3
|
21 |
464 |
1.2e-15 |
PFAM |
|
AAA
|
547 |
729 |
5.71e-12 |
SMART |
|
low complexity region
|
846 |
857 |
N/A |
INTRINSIC |
|
Pfam:ABC2_membrane_3
|
905 |
1307 |
1.1e-32 |
PFAM |
|
low complexity region
|
1337 |
1351 |
N/A |
INTRINSIC |
|
AAA
|
1393 |
1577 |
1.15e-1 |
SMART |
|
low complexity region
|
1697 |
1730 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 99.4%
- 3x: 98.9%
- 10x: 97.7%
- 20x: 96.1%
|
| Validation Efficiency |
99% (125/126) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 115 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700067K01Rik |
T |
C |
8: 84,729,637 (GRCm39) |
|
probably benign |
Het |
| A530064D06Rik |
G |
A |
17: 48,473,824 (GRCm39) |
T31I |
probably benign |
Het |
| Abcf3 |
T |
A |
16: 20,369,237 (GRCm39) |
N206K |
probably damaging |
Het |
| Adam10 |
A |
G |
9: 70,673,223 (GRCm39) |
|
probably benign |
Het |
| Adamtsl3 |
A |
T |
7: 82,172,390 (GRCm39) |
Q451L |
probably damaging |
Het |
| Adgrl3 |
T |
A |
5: 81,708,752 (GRCm39) |
I413N |
probably benign |
Het |
| Asb18 |
G |
T |
1: 89,920,893 (GRCm39) |
A128E |
probably damaging |
Het |
| Atf7ip2 |
T |
C |
16: 10,059,743 (GRCm39) |
S428P |
possibly damaging |
Het |
| Atp8b5 |
G |
T |
4: 43,291,672 (GRCm39) |
C15F |
possibly damaging |
Het |
| Bahcc1 |
A |
G |
11: 120,178,146 (GRCm39) |
E2235G |
probably damaging |
Het |
| Blnk |
G |
T |
19: 40,926,111 (GRCm39) |
S330* |
probably null |
Het |
| Bpnt1 |
T |
G |
1: 185,088,808 (GRCm39) |
N319K |
probably benign |
Het |
| Brip1 |
G |
A |
11: 86,043,493 (GRCm39) |
T357I |
possibly damaging |
Het |
| Cadm1 |
T |
A |
9: 47,725,104 (GRCm39) |
D288E |
probably benign |
Het |
| Calcoco2 |
A |
G |
11: 95,998,354 (GRCm39) |
V23A |
probably damaging |
Het |
| Cand2 |
G |
A |
6: 115,780,766 (GRCm39) |
E1217K |
probably damaging |
Het |
| Ccdc154 |
G |
T |
17: 25,386,259 (GRCm39) |
|
probably benign |
Het |
| Cdk12 |
T |
C |
11: 98,120,935 (GRCm39) |
|
probably benign |
Het |
| Clec4a3 |
A |
G |
6: 122,930,993 (GRCm39) |
|
probably null |
Het |
| Cpne2 |
T |
A |
8: 95,274,970 (GRCm39) |
|
probably benign |
Het |
| Cyfip1 |
T |
C |
7: 55,573,710 (GRCm39) |
|
probably null |
Het |
| Cyp26c1 |
A |
G |
19: 37,675,009 (GRCm39) |
H110R |
probably damaging |
Het |
| Cyp2j13 |
A |
G |
4: 95,959,932 (GRCm39) |
Y75H |
probably damaging |
Het |
| Defb43 |
T |
A |
14: 63,249,287 (GRCm39) |
V10D |
probably damaging |
Het |
| Dhx36 |
G |
A |
3: 62,401,162 (GRCm39) |
S368L |
possibly damaging |
Het |
| Dock6 |
G |
A |
9: 21,715,923 (GRCm39) |
|
probably benign |
Het |
| Elp2 |
T |
C |
18: 24,745,499 (GRCm39) |
|
probably benign |
Het |
| Emilin3 |
A |
G |
2: 160,750,249 (GRCm39) |
L453P |
probably damaging |
Het |
| Eml6 |
A |
T |
11: 29,755,065 (GRCm39) |
D903E |
probably benign |
Het |
| Ep300 |
T |
C |
15: 81,500,335 (GRCm39) |
|
probably benign |
Het |
| Ep400 |
G |
A |
5: 110,836,062 (GRCm39) |
T1899M |
unknown |
Het |
| Fancg |
A |
G |
4: 43,002,998 (GRCm39) |
S620P |
probably benign |
Het |
| Fbxo42 |
G |
A |
4: 140,922,550 (GRCm39) |
V239M |
probably damaging |
Het |
| Fermt2 |
T |
C |
14: 45,706,776 (GRCm39) |
D340G |
probably benign |
Het |
| Filip1 |
A |
T |
9: 79,726,672 (GRCm39) |
V649E |
probably damaging |
Het |
| Fut8 |
G |
A |
12: 77,521,791 (GRCm39) |
E477K |
probably damaging |
Het |
| Gbp3 |
G |
A |
3: 142,271,151 (GRCm39) |
G185D |
probably benign |
Het |
| Gclc |
G |
T |
9: 77,694,080 (GRCm39) |
D345Y |
probably damaging |
Het |
| Gfus |
A |
G |
15: 75,800,807 (GRCm39) |
V27A |
possibly damaging |
Het |
| Gkn2 |
A |
G |
6: 87,352,800 (GRCm39) |
D43G |
possibly damaging |
Het |
| Gnptab |
A |
G |
10: 88,279,166 (GRCm39) |
|
probably benign |
Het |
| Greb1l |
C |
T |
18: 10,474,303 (GRCm39) |
T206I |
probably damaging |
Het |
| Grk4 |
A |
G |
5: 34,905,611 (GRCm39) |
N452S |
probably benign |
Het |
| Hcn2 |
G |
C |
10: 79,570,066 (GRCm39) |
|
probably null |
Het |
| Hpn |
T |
C |
7: 30,808,585 (GRCm39) |
K76E |
possibly damaging |
Het |
| Hspg2 |
A |
G |
4: 137,280,591 (GRCm39) |
D3268G |
probably damaging |
Het |
| Immt |
A |
T |
6: 71,848,541 (GRCm39) |
Q467L |
possibly damaging |
Het |
| Kalrn |
T |
C |
16: 33,936,778 (GRCm39) |
S1636G |
probably benign |
Het |
| Kcnh8 |
T |
A |
17: 53,285,141 (GRCm39) |
L1037* |
probably null |
Het |
| Klhl33 |
T |
C |
14: 51,129,851 (GRCm39) |
T548A |
probably damaging |
Het |
| Klri2 |
T |
C |
6: 129,717,171 (GRCm39) |
I71V |
probably benign |
Het |
| Kmt2c |
A |
T |
5: 25,609,363 (GRCm39) |
C254S |
probably damaging |
Het |
| Lama3 |
T |
C |
18: 12,610,647 (GRCm39) |
I1170T |
possibly damaging |
Het |
| Med12l |
A |
G |
3: 59,172,350 (GRCm39) |
Q1702R |
probably damaging |
Het |
| Mga |
A |
T |
2: 119,750,391 (GRCm39) |
|
probably null |
Het |
| Mis18a |
A |
T |
16: 90,517,561 (GRCm39) |
I172K |
possibly damaging |
Het |
| Mrgpre |
T |
C |
7: 143,335,254 (GRCm39) |
D83G |
probably benign |
Het |
| Mroh2a |
C |
A |
1: 88,170,142 (GRCm39) |
A685D |
possibly damaging |
Het |
| Mrpl39 |
T |
C |
16: 84,531,282 (GRCm39) |
|
probably benign |
Het |
| Mrrf |
C |
T |
2: 36,043,710 (GRCm39) |
A149V |
probably benign |
Het |
| Mycbp2 |
A |
T |
14: 103,432,024 (GRCm39) |
M2338K |
possibly damaging |
Het |
| Myo18b |
T |
C |
5: 112,840,632 (GRCm39) |
Q2387R |
probably benign |
Het |
| N4bp2 |
T |
C |
5: 65,964,780 (GRCm39) |
I943T |
probably damaging |
Het |
| Ncapd3 |
T |
A |
9: 26,998,773 (GRCm39) |
N1254K |
probably benign |
Het |
| Ncoa1 |
A |
T |
12: 4,299,758 (GRCm39) |
|
probably null |
Het |
| Ncor2 |
C |
T |
5: 125,126,451 (GRCm39) |
A136T |
probably benign |
Het |
| Opa1 |
T |
C |
16: 29,421,025 (GRCm39) |
|
probably benign |
Het |
| Or13a25 |
A |
G |
7: 140,247,590 (GRCm39) |
D123G |
probably damaging |
Het |
| Or5p59 |
C |
A |
7: 107,703,363 (GRCm39) |
Y282* |
probably null |
Het |
| Or8b39 |
T |
A |
9: 37,996,423 (GRCm39) |
M97K |
possibly damaging |
Het |
| Or9e1 |
T |
A |
11: 58,732,681 (GRCm39) |
I247N |
possibly damaging |
Het |
| Pcdhb4 |
T |
C |
18: 37,440,795 (GRCm39) |
M35T |
probably benign |
Het |
| Per3 |
T |
C |
4: 151,113,288 (GRCm39) |
I347V |
probably benign |
Het |
| Pex13 |
G |
A |
11: 23,615,831 (GRCm39) |
P5L |
possibly damaging |
Het |
| Phkb |
T |
A |
8: 86,602,322 (GRCm39) |
W38R |
probably damaging |
Het |
| Plekhf1 |
A |
T |
7: 37,920,826 (GRCm39) |
D247E |
probably benign |
Het |
| Plxnb2 |
A |
G |
15: 89,042,184 (GRCm39) |
S1607P |
probably benign |
Het |
| Plxnc1 |
T |
A |
10: 94,635,194 (GRCm39) |
H1344L |
possibly damaging |
Het |
| Potefam1 |
A |
C |
2: 111,034,482 (GRCm39) |
V350G |
possibly damaging |
Het |
| Ptk7 |
T |
G |
17: 46,901,238 (GRCm39) |
N196H |
possibly damaging |
Het |
| Rab27a |
G |
T |
9: 72,982,715 (GRCm39) |
D7Y |
probably damaging |
Het |
| Rars2 |
T |
A |
4: 34,630,505 (GRCm39) |
C82* |
probably null |
Het |
| Rccd1 |
A |
T |
7: 79,969,965 (GRCm39) |
|
probably benign |
Het |
| Riiad1 |
T |
C |
3: 94,379,546 (GRCm39) |
I56V |
possibly damaging |
Het |
| Rnase4 |
A |
G |
14: 51,342,507 (GRCm39) |
E77G |
probably damaging |
Het |
| Rnf126 |
A |
T |
10: 79,597,441 (GRCm39) |
I157N |
possibly damaging |
Het |
| Rnf207 |
T |
C |
4: 152,391,925 (GRCm39) |
R623G |
probably benign |
Het |
| Rpusd1 |
T |
G |
17: 25,947,498 (GRCm39) |
F62V |
possibly damaging |
Het |
| Rxfp1 |
T |
C |
3: 79,570,600 (GRCm39) |
|
probably null |
Het |
| Scfd1 |
A |
T |
12: 51,459,411 (GRCm39) |
Q324L |
probably benign |
Het |
| Skint3 |
G |
T |
4: 112,112,974 (GRCm39) |
E195* |
probably null |
Het |
| Slc7a10 |
A |
T |
7: 34,896,758 (GRCm39) |
T165S |
probably benign |
Het |
| Smagp |
A |
G |
15: 100,519,733 (GRCm39) |
I97T |
probably damaging |
Het |
| Sostdc1 |
A |
G |
12: 36,367,340 (GRCm39) |
H172R |
probably damaging |
Het |
| Spast |
A |
G |
17: 74,646,446 (GRCm39) |
|
probably benign |
Het |
| Sspo |
G |
T |
6: 48,467,325 (GRCm39) |
|
probably benign |
Het |
| Ston2 |
C |
T |
12: 91,707,240 (GRCm39) |
|
probably null |
Het |
| Tas2r103 |
T |
G |
6: 133,013,313 (GRCm39) |
E251A |
probably benign |
Het |
| Tbc1d2b |
A |
T |
9: 90,104,558 (GRCm39) |
|
probably benign |
Het |
| Telo2 |
G |
A |
17: 25,332,139 (GRCm39) |
P143L |
probably benign |
Het |
| Tgfbi |
A |
T |
13: 56,786,539 (GRCm39) |
Y674F |
probably null |
Het |
| Tha1 |
T |
A |
11: 117,763,983 (GRCm39) |
|
probably benign |
Het |
| Timp4 |
T |
A |
6: 115,226,814 (GRCm39) |
S110C |
probably damaging |
Het |
| Tlr6 |
T |
C |
5: 65,111,935 (GRCm39) |
K324R |
probably benign |
Het |
| Tnip3 |
A |
G |
6: 65,574,347 (GRCm39) |
E137G |
probably damaging |
Het |
| Top6bl |
A |
G |
19: 4,676,216 (GRCm39) |
S639P |
probably damaging |
Het |
| Trak1 |
T |
C |
9: 121,278,021 (GRCm39) |
|
probably null |
Het |
| Trim47 |
A |
G |
11: 115,999,178 (GRCm39) |
S233P |
probably benign |
Het |
| Tspoap1 |
A |
T |
11: 87,653,635 (GRCm39) |
E155V |
probably damaging |
Het |
| Uggt1 |
A |
T |
1: 36,194,209 (GRCm39) |
L1343Q |
probably damaging |
Het |
| Utp14b |
T |
C |
1: 78,642,452 (GRCm39) |
S117P |
probably benign |
Het |
| Vmn1r124 |
A |
T |
7: 20,994,436 (GRCm39) |
V36D |
probably damaging |
Het |
| Wdr27 |
T |
C |
17: 15,148,658 (GRCm39) |
T112A |
probably benign |
Het |
| Wdr90 |
T |
C |
17: 26,065,367 (GRCm39) |
T1630A |
probably benign |
Het |
| Zfp352 |
A |
G |
4: 90,112,156 (GRCm39) |
T99A |
probably benign |
Het |
|
| Other mutations in Abca17 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00402:Abca17
|
APN |
17 |
24,514,165 (GRCm39) |
missense |
probably benign |
0.14 |
|
IGL00585:Abca17
|
APN |
17 |
24,519,294 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL00941:Abca17
|
APN |
17 |
24,536,104 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01987:Abca17
|
APN |
17 |
24,565,202 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01988:Abca17
|
APN |
17 |
24,553,229 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02223:Abca17
|
APN |
17 |
24,506,909 (GRCm39) |
nonsense |
probably null |
|
|
IGL02368:Abca17
|
APN |
17 |
24,506,767 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02405:Abca17
|
APN |
17 |
24,498,036 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
IGL02431:Abca17
|
APN |
17 |
24,517,958 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02607:Abca17
|
APN |
17 |
24,546,679 (GRCm39) |
nonsense |
probably null |
|
|
IGL02706:Abca17
|
APN |
17 |
24,517,966 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02729:Abca17
|
APN |
17 |
24,499,455 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL02818:Abca17
|
APN |
17 |
24,519,326 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02891:Abca17
|
APN |
17 |
24,500,340 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03236:Abca17
|
APN |
17 |
24,545,450 (GRCm39) |
splice site |
probably benign |
|
|
IGL03299:Abca17
|
APN |
17 |
24,484,565 (GRCm39) |
missense |
probably damaging |
1.00 |
|
basin
|
UTSW |
17 |
24,537,159 (GRCm39) |
missense |
probably benign |
0.01 |
|
Bowl
|
UTSW |
17 |
24,536,212 (GRCm39) |
missense |
probably benign |
0.09 |
|
R0018:Abca17
|
UTSW |
17 |
24,532,162 (GRCm39) |
splice site |
probably null |
|
|
R0467:Abca17
|
UTSW |
17 |
24,532,151 (GRCm39) |
splice site |
probably benign |
|
|
R1175:Abca17
|
UTSW |
17 |
24,508,325 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R1397:Abca17
|
UTSW |
17 |
24,504,733 (GRCm39) |
missense |
probably benign |
0.18 |
|
R1398:Abca17
|
UTSW |
17 |
24,547,511 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1678:Abca17
|
UTSW |
17 |
24,554,594 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1696:Abca17
|
UTSW |
17 |
24,486,632 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R1781:Abca17
|
UTSW |
17 |
24,486,531 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1845:Abca17
|
UTSW |
17 |
24,486,690 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1970:Abca17
|
UTSW |
17 |
24,526,549 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1997:Abca17
|
UTSW |
17 |
24,504,700 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2141:Abca17
|
UTSW |
17 |
24,553,240 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2199:Abca17
|
UTSW |
17 |
24,554,598 (GRCm39) |
missense |
probably benign |
0.19 |
|
R2394:Abca17
|
UTSW |
17 |
24,500,190 (GRCm39) |
splice site |
probably null |
|
|
R2442:Abca17
|
UTSW |
17 |
24,547,606 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2509:Abca17
|
UTSW |
17 |
24,508,587 (GRCm39) |
splice site |
probably benign |
|
|
R2848:Abca17
|
UTSW |
17 |
24,508,481 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R2849:Abca17
|
UTSW |
17 |
24,508,481 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R2859:Abca17
|
UTSW |
17 |
24,500,288 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R2879:Abca17
|
UTSW |
17 |
24,508,481 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R2935:Abca17
|
UTSW |
17 |
24,508,481 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R3153:Abca17
|
UTSW |
17 |
24,547,720 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3154:Abca17
|
UTSW |
17 |
24,547,720 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3434:Abca17
|
UTSW |
17 |
24,508,511 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3695:Abca17
|
UTSW |
17 |
24,508,481 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R3905:Abca17
|
UTSW |
17 |
24,515,257 (GRCm39) |
missense |
probably benign |
0.13 |
|
R4282:Abca17
|
UTSW |
17 |
24,518,034 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R4334:Abca17
|
UTSW |
17 |
24,537,242 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4350:Abca17
|
UTSW |
17 |
24,498,020 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4548:Abca17
|
UTSW |
17 |
24,553,245 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R4626:Abca17
|
UTSW |
17 |
24,540,058 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4722:Abca17
|
UTSW |
17 |
24,484,403 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4745:Abca17
|
UTSW |
17 |
24,526,427 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4818:Abca17
|
UTSW |
17 |
24,536,135 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5279:Abca17
|
UTSW |
17 |
24,508,388 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5310:Abca17
|
UTSW |
17 |
24,500,204 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5320:Abca17
|
UTSW |
17 |
24,526,541 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5435:Abca17
|
UTSW |
17 |
24,486,588 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5622:Abca17
|
UTSW |
17 |
24,546,642 (GRCm39) |
missense |
probably benign |
0.14 |
|
R5776:Abca17
|
UTSW |
17 |
24,514,132 (GRCm39) |
missense |
probably benign |
0.09 |
|
R5928:Abca17
|
UTSW |
17 |
24,537,159 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6013:Abca17
|
UTSW |
17 |
24,506,820 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R6035:Abca17
|
UTSW |
17 |
24,500,219 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R6035:Abca17
|
UTSW |
17 |
24,500,219 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R6052:Abca17
|
UTSW |
17 |
24,537,165 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6063:Abca17
|
UTSW |
17 |
24,483,318 (GRCm39) |
missense |
unknown |
|
|
R6404:Abca17
|
UTSW |
17 |
24,484,892 (GRCm39) |
missense |
probably benign |
0.13 |
|
R6746:Abca17
|
UTSW |
17 |
24,565,195 (GRCm39) |
nonsense |
probably null |
|
|
R6819:Abca17
|
UTSW |
17 |
24,506,767 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6828:Abca17
|
UTSW |
17 |
24,545,389 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R7043:Abca17
|
UTSW |
17 |
24,484,474 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7065:Abca17
|
UTSW |
17 |
24,546,725 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7123:Abca17
|
UTSW |
17 |
24,484,949 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7157:Abca17
|
UTSW |
17 |
24,554,564 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7188:Abca17
|
UTSW |
17 |
24,554,600 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7294:Abca17
|
UTSW |
17 |
24,539,983 (GRCm39) |
missense |
not run |
|
|
R7352:Abca17
|
UTSW |
17 |
24,508,028 (GRCm39) |
nonsense |
probably null |
|
|
R7355:Abca17
|
UTSW |
17 |
24,486,621 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7358:Abca17
|
UTSW |
17 |
24,510,529 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7411:Abca17
|
UTSW |
17 |
24,547,543 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R7915:Abca17
|
UTSW |
17 |
24,484,507 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8039:Abca17
|
UTSW |
17 |
24,547,699 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8095:Abca17
|
UTSW |
17 |
24,536,196 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R8308:Abca17
|
UTSW |
17 |
24,486,657 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8517:Abca17
|
UTSW |
17 |
24,536,207 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8811:Abca17
|
UTSW |
17 |
24,536,212 (GRCm39) |
missense |
probably benign |
0.09 |
|
R8819:Abca17
|
UTSW |
17 |
24,547,576 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8820:Abca17
|
UTSW |
17 |
24,547,576 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8953:Abca17
|
UTSW |
17 |
24,518,015 (GRCm39) |
missense |
probably benign |
|
|
R9095:Abca17
|
UTSW |
17 |
24,500,370 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9313:Abca17
|
UTSW |
17 |
24,565,207 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9314:Abca17
|
UTSW |
17 |
24,547,593 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9347:Abca17
|
UTSW |
17 |
24,483,479 (GRCm39) |
missense |
probably benign |
|
|
R9351:Abca17
|
UTSW |
17 |
24,510,751 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9387:Abca17
|
UTSW |
17 |
24,553,255 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9388:Abca17
|
UTSW |
17 |
24,483,273 (GRCm39) |
missense |
unknown |
|
|
R9440:Abca17
|
UTSW |
17 |
24,499,452 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9498:Abca17
|
UTSW |
17 |
24,484,480 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9654:Abca17
|
UTSW |
17 |
24,536,099 (GRCm39) |
missense |
probably benign |
0.09 |
|
R9709:Abca17
|
UTSW |
17 |
24,517,934 (GRCm39) |
missense |
probably benign |
|
|
R9770:Abca17
|
UTSW |
17 |
24,514,121 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9773:Abca17
|
UTSW |
17 |
24,508,565 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF024:Abca17
|
UTSW |
17 |
24,506,706 (GRCm39) |
frame shift |
probably null |
|
|
RF029:Abca17
|
UTSW |
17 |
24,506,701 (GRCm39) |
critical splice donor site |
probably benign |
|
|
RF032:Abca17
|
UTSW |
17 |
24,506,701 (GRCm39) |
frame shift |
probably null |
|
|
RF036:Abca17
|
UTSW |
17 |
24,506,701 (GRCm39) |
critical splice donor site |
probably benign |
|
|
X0017:Abca17
|
UTSW |
17 |
24,536,137 (GRCm39) |
missense |
probably benign |
0.26 |
|
X0065:Abca17
|
UTSW |
17 |
24,553,258 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Abca17
|
UTSW |
17 |
24,498,081 (GRCm39) |
missense |
probably benign |
0.03 |
|
Z1088:Abca17
|
UTSW |
17 |
24,498,053 (GRCm39) |
missense |
probably damaging |
0.96 |
|
Z1088:Abca17
|
UTSW |
17 |
24,565,193 (GRCm39) |
missense |
probably damaging |
0.98 |
|
| Predicted Primers |
PCR Primer
(F):5'- CATTTGACGAGCTGGCCCTAGATAC -3'
(R):5'- TGGTCCAAGAGAACATCTACGCCTG -3'
Sequencing Primer
(F):5'- TACTCCCCAGGTGACCAGTATG -3'
(R):5'- GAGAACATCTACGCCTGGGAATC -3'
|
| Posted On |
2013-07-30 |
Incidental Mutation