Incidental Mutation 'R7998:Shprh'
| ID |
616201 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Shprh
|
| Ensembl Gene |
ENSMUSG00000090112 |
| Gene Name |
SNF2 histone linker PHD RING helicase |
| Synonyms |
2610103K11Rik, D230017O13Rik |
| MMRRC Submission |
046038-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7998 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
10 |
| Chromosomal Location |
11149427-11217595 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 11185341 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Tryptophan to Arginine
at position 1133
(W1133R)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000039422
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000044053]
[ENSMUST00000054814]
[ENSMUST00000159541]
[ENSMUST00000159810]
|
| AlphaFold |
Q7TPQ3 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000044053
AA Change: W1133R
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000039422
Gene: ENSMUSG00000090112
AA Change: W1133R
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
42 |
56 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
195 |
250 |
3e-12 |
BLAST |
|
low complexity region
|
253 |
265 |
N/A |
INTRINSIC |
|
DEXDc
|
295 |
866 |
4.02e-17 |
SMART |
|
H15
|
431 |
497 |
3.76e-5 |
SMART |
|
PHD
|
651 |
698 |
2.33e-5 |
SMART |
|
low complexity region
|
1393 |
1404 |
N/A |
INTRINSIC |
|
RING
|
1423 |
1469 |
9.68e-3 |
SMART |
|
Pfam:Helicase_C
|
1500 |
1613 |
1.6e-8 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000054814
AA Change: W1133R
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000125849
Gene: ENSMUSG00000090112
AA Change: W1133R
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
42 |
56 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
195 |
250 |
3e-12 |
BLAST |
|
low complexity region
|
253 |
265 |
N/A |
INTRINSIC |
|
DEXDc
|
295 |
866 |
4.02e-17 |
SMART |
|
H15
|
431 |
497 |
3.76e-5 |
SMART |
|
PHD
|
651 |
698 |
2.33e-5 |
SMART |
|
low complexity region
|
1393 |
1404 |
N/A |
INTRINSIC |
|
RING
|
1423 |
1469 |
9.68e-3 |
SMART |
|
SCOP:d1fuka_
|
1504 |
1616 |
6e-8 |
SMART |
|
Blast:HELICc
|
1533 |
1613 |
4e-46 |
BLAST |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000159541
AA Change: W1133R
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000132870
Gene: ENSMUSG00000090112
AA Change: W1133R
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
42 |
56 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
195 |
250 |
3e-12 |
BLAST |
|
low complexity region
|
253 |
265 |
N/A |
INTRINSIC |
|
DEXDc
|
295 |
866 |
4.02e-17 |
SMART |
|
H15
|
431 |
497 |
3.76e-5 |
SMART |
|
PHD
|
651 |
698 |
2.33e-5 |
SMART |
|
low complexity region
|
1393 |
1404 |
N/A |
INTRINSIC |
|
RING
|
1423 |
1469 |
9.68e-3 |
SMART |
|
SCOP:d1fuka_
|
1504 |
1619 |
4e-8 |
SMART |
|
Blast:HELICc
|
1533 |
1613 |
6e-46 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000159810
|
| SMART Domains |
Protein: ENSMUSP00000125457
Gene: ENSMUSG00000090112
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
42 |
56 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
195 |
250 |
2e-12 |
BLAST |
|
low complexity region
|
253 |
265 |
N/A |
INTRINSIC |
|
DEXDc
|
295 |
866 |
4.02e-17 |
SMART |
|
H15
|
431 |
497 |
3.76e-5 |
SMART |
|
PHD
|
651 |
698 |
2.33e-5 |
SMART |
|
Blast:DEXDc
|
948 |
1026 |
2e-9 |
BLAST |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 98.9%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] SHPRH is a ubiquitously expressed protein that contains motifs characteristics of several DNA repair proteins, transcription factors, and helicases. SHPRH is a functional homolog of S. cerevisiae RAD5 (Unk et al., 2006 [PubMed 17108083]).[supplied by OMIM, Mar 2008]
PHENOTYPE: The gene product is an E3 ligase involved in poly-ubiquitination of Pcna. Neither homozygous truncation nor KO affect B cell somatic hypermutation or class switching. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 63 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930474N05Rik |
C |
T |
14: 36,096,692 (GRCm38) |
R216C |
probably benign |
Het |
| Acsl3 |
C |
T |
1: 78,694,271 (GRCm38) |
P294L |
probably damaging |
Het |
| Alox12b |
T |
C |
11: 69,168,837 (GRCm38) |
Y572H |
probably damaging |
Het |
| Arid1b |
A |
G |
17: 5,327,684 (GRCm38) |
D1236G |
probably damaging |
Het |
| Astl |
T |
C |
2: 127,350,499 (GRCm38) |
L254P |
probably damaging |
Het |
| Btbd7 |
A |
C |
12: 102,795,240 (GRCm38) |
L562R |
probably damaging |
Het |
| Chl1 |
T |
C |
6: 103,729,289 (GRCm38) |
V1195A |
probably benign |
Het |
| Ciao2b |
T |
A |
8: 104,641,036 (GRCm38) |
S94C |
probably damaging |
Het |
| Cib1 |
A |
T |
7: 80,228,414 (GRCm38) |
Y105* |
probably null |
Het |
| Cog3 |
G |
T |
14: 75,747,093 (GRCm38) |
S94Y |
possibly damaging |
Het |
| Cpne6 |
A |
C |
14: 55,516,294 (GRCm38) |
Q403P |
probably damaging |
Het |
| Csn1s1 |
A |
G |
5: 87,674,228 (GRCm38) |
N119S |
possibly damaging |
Het |
| Cux2 |
T |
C |
5: 121,868,585 (GRCm38) |
D874G |
possibly damaging |
Het |
| Dicer1 |
A |
T |
12: 104,704,069 (GRCm38) |
F1079Y |
probably damaging |
Het |
| Dsc2 |
T |
A |
18: 20,034,663 (GRCm38) |
Q724H |
possibly damaging |
Het |
| Fbxw16 |
A |
G |
9: 109,436,698 (GRCm38) |
V351A |
probably damaging |
Het |
| G2e3 |
A |
T |
12: 51,353,841 (GRCm38) |
E59D |
probably benign |
Het |
| Gm10800 |
A |
AC |
2: 98,667,033 (GRCm38) |
|
probably null |
Het |
| Gm10837 |
G |
T |
14: 122,490,641 (GRCm38) |
|
probably benign |
Het |
| Gpr137b |
T |
C |
13: 13,359,406 (GRCm38) |
Y355C |
|
Het |
| Gpr18 |
T |
C |
14: 121,911,981 (GRCm38) |
I211V |
probably benign |
Het |
| Gstm7 |
T |
A |
3: 107,930,341 (GRCm38) |
D98V |
probably damaging |
Het |
| Hspa8 |
A |
G |
9: 40,804,514 (GRCm38) |
Y525C |
probably damaging |
Het |
| Itga7 |
T |
C |
10: 128,934,151 (GRCm38) |
S55P |
probably damaging |
Het |
| Itpr1 |
T |
C |
6: 108,417,948 (GRCm38) |
V1674A |
possibly damaging |
Het |
| Itsn1 |
G |
T |
16: 91,850,936 (GRCm38) |
G893C |
unknown |
Het |
| Kcnc1 |
A |
G |
7: 46,397,799 (GRCm38) |
D41G |
probably benign |
Het |
| Larp6 |
A |
G |
9: 60,724,355 (GRCm38) |
K137E |
probably damaging |
Het |
| Leo1 |
G |
T |
9: 75,445,276 (GRCm38) |
G34C |
probably benign |
Het |
| Map4 |
G |
A |
9: 110,079,861 (GRCm38) |
V1050M |
probably damaging |
Het |
| Mast3 |
A |
G |
8: 70,783,570 (GRCm38) |
V722A |
probably benign |
Het |
| Med28 |
T |
A |
5: 45,525,199 (GRCm38) |
V69D |
probably damaging |
Het |
| Mier1 |
T |
C |
4: 103,162,615 (GRCm38) |
F512S |
probably benign |
Het |
| Mix23 |
T |
A |
16: 36,085,033 (GRCm38) |
V65D |
probably benign |
Het |
| Mov10l1 |
T |
A |
15: 89,053,439 (GRCm38) |
V1147E |
probably damaging |
Het |
| Mroh7 |
T |
C |
4: 106,711,281 (GRCm38) |
E409G |
probably benign |
Het |
| Muc16 |
G |
T |
9: 18,639,892 (GRCm38) |
P5035Q |
probably benign |
Het |
| Nemp1 |
C |
A |
10: 127,693,489 (GRCm38) |
S213R |
probably damaging |
Het |
| Npffr2 |
T |
C |
5: 89,583,290 (GRCm38) |
Y360H |
probably damaging |
Het |
| Nrxn2 |
T |
C |
19: 6,509,875 (GRCm38) |
V1221A |
probably damaging |
Het |
| Nup107 |
A |
G |
10: 117,757,994 (GRCm38) |
F765L |
probably damaging |
Het |
| Nup188 |
T |
C |
2: 30,330,971 (GRCm38) |
L991P |
probably damaging |
Het |
| Or13f5 |
A |
T |
4: 52,825,970 (GRCm38) |
D191V |
possibly damaging |
Het |
| Or5ac23 |
T |
A |
16: 59,329,270 (GRCm38) |
M80L |
probably benign |
Het |
| Pla2g7 |
A |
T |
17: 43,611,318 (GRCm38) |
I363L |
probably benign |
Het |
| Ppp2r1a |
T |
C |
17: 20,961,639 (GRCm38) |
F473S |
possibly damaging |
Het |
| Prex1 |
A |
G |
2: 166,587,045 (GRCm38) |
|
probably null |
Het |
| Ptov1 |
A |
G |
7: 44,864,929 (GRCm38) |
V263A |
probably damaging |
Het |
| Reg3a |
T |
C |
6: 78,381,149 (GRCm38) |
V21A |
probably benign |
Het |
| Sdk2 |
T |
A |
11: 113,859,938 (GRCm38) |
I550F |
probably benign |
Het |
| Slc28a2b |
T |
C |
2: 122,494,358 (GRCm38) |
L137P |
probably damaging |
Het |
| Syne2 |
T |
C |
12: 76,087,858 (GRCm38) |
V1297A |
probably damaging |
Het |
| Themis2 |
A |
G |
4: 132,792,564 (GRCm38) |
I50T |
probably damaging |
Het |
| Tmprss15 |
C |
A |
16: 79,001,843 (GRCm38) |
L650F |
possibly damaging |
Het |
| Ttc41 |
C |
A |
10: 86,736,847 (GRCm38) |
N694K |
probably benign |
Het |
| Ttll9 |
T |
C |
2: 152,991,626 (GRCm38) |
Y215H |
possibly damaging |
Het |
| Ttn |
C |
A |
2: 76,903,309 (GRCm38) |
V4541L |
unknown |
Het |
| Usp32 |
G |
T |
11: 84,994,426 (GRCm38) |
A1265E |
probably damaging |
Het |
| Vcan |
T |
A |
13: 89,704,327 (GRCm38) |
D838V |
probably damaging |
Het |
| Vmn2r88 |
T |
C |
14: 51,414,108 (GRCm38) |
I293T |
|
Het |
| Wdr36 |
T |
G |
18: 32,852,519 (GRCm38) |
D496E |
probably damaging |
Het |
| Wrn |
T |
C |
8: 33,292,643 (GRCm38) |
N753S |
probably benign |
Het |
| Zmat3 |
T |
C |
3: 32,341,666 (GRCm38) |
R231G |
possibly damaging |
Het |
|
| Other mutations in Shprh |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00492:Shprh
|
APN |
10 |
11,188,158 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL00583:Shprh
|
APN |
10 |
11,188,020 (GRCm38) |
missense |
probably benign |
0.37 |
|
IGL00684:Shprh
|
APN |
10 |
11,163,037 (GRCm38) |
missense |
probably benign |
0.11 |
|
IGL01295:Shprh
|
APN |
10 |
11,183,868 (GRCm38) |
missense |
probably damaging |
0.96 |
|
IGL01387:Shprh
|
APN |
10 |
11,170,254 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01635:Shprh
|
APN |
10 |
11,170,019 (GRCm38) |
nonsense |
probably null |
|
|
IGL01833:Shprh
|
APN |
10 |
11,191,062 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02013:Shprh
|
APN |
10 |
11,181,502 (GRCm38) |
splice site |
probably benign |
|
|
IGL02502:Shprh
|
APN |
10 |
11,194,357 (GRCm38) |
missense |
possibly damaging |
0.66 |
|
IGL02819:Shprh
|
APN |
10 |
11,154,765 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
PIT4581001:Shprh
|
UTSW |
10 |
11,192,494 (GRCm38) |
frame shift |
probably null |
|
|
R0010:Shprh
|
UTSW |
10 |
11,151,931 (GRCm38) |
missense |
probably benign |
|
|
R0010:Shprh
|
UTSW |
10 |
11,151,931 (GRCm38) |
missense |
probably benign |
|
|
R0053:Shprh
|
UTSW |
10 |
11,194,372 (GRCm38) |
splice site |
probably null |
|
|
R0053:Shprh
|
UTSW |
10 |
11,194,372 (GRCm38) |
splice site |
probably null |
|
|
R0255:Shprh
|
UTSW |
10 |
11,186,391 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R0325:Shprh
|
UTSW |
10 |
11,170,109 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0331:Shprh
|
UTSW |
10 |
11,194,170 (GRCm38) |
splice site |
probably benign |
|
|
R0494:Shprh
|
UTSW |
10 |
11,157,191 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0532:Shprh
|
UTSW |
10 |
11,162,812 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R0546:Shprh
|
UTSW |
10 |
11,183,887 (GRCm38) |
splice site |
probably benign |
|
|
R0574:Shprh
|
UTSW |
10 |
11,163,077 (GRCm38) |
unclassified |
probably benign |
|
|
R0605:Shprh
|
UTSW |
10 |
11,207,112 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0662:Shprh
|
UTSW |
10 |
11,186,847 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1148:Shprh
|
UTSW |
10 |
11,213,482 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R1148:Shprh
|
UTSW |
10 |
11,213,482 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R1263:Shprh
|
UTSW |
10 |
11,159,530 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1588:Shprh
|
UTSW |
10 |
11,164,744 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1638:Shprh
|
UTSW |
10 |
11,157,078 (GRCm38) |
missense |
probably benign |
|
|
R1830:Shprh
|
UTSW |
10 |
11,186,911 (GRCm38) |
splice site |
probably null |
|
|
R1898:Shprh
|
UTSW |
10 |
11,186,869 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1903:Shprh
|
UTSW |
10 |
11,183,797 (GRCm38) |
nonsense |
probably null |
|
|
R2060:Shprh
|
UTSW |
10 |
11,152,120 (GRCm38) |
missense |
probably benign |
0.03 |
|
R2225:Shprh
|
UTSW |
10 |
11,162,235 (GRCm38) |
unclassified |
probably benign |
|
|
R2363:Shprh
|
UTSW |
10 |
11,171,953 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2509:Shprh
|
UTSW |
10 |
11,166,724 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2891:Shprh
|
UTSW |
10 |
11,164,356 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3077:Shprh
|
UTSW |
10 |
11,170,413 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3150:Shprh
|
UTSW |
10 |
11,170,030 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R3796:Shprh
|
UTSW |
10 |
11,178,757 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
R4196:Shprh
|
UTSW |
10 |
11,207,860 (GRCm38) |
utr 3 prime |
probably benign |
|
|
R4423:Shprh
|
UTSW |
10 |
11,186,518 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
R4488:Shprh
|
UTSW |
10 |
11,160,471 (GRCm38) |
missense |
probably benign |
0.17 |
|
R4748:Shprh
|
UTSW |
10 |
11,170,476 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4768:Shprh
|
UTSW |
10 |
11,181,540 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R4867:Shprh
|
UTSW |
10 |
11,164,557 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4937:Shprh
|
UTSW |
10 |
11,157,119 (GRCm38) |
missense |
probably benign |
|
|
R5140:Shprh
|
UTSW |
10 |
11,154,705 (GRCm38) |
missense |
probably benign |
0.03 |
|
R5318:Shprh
|
UTSW |
10 |
11,166,557 (GRCm38) |
missense |
probably benign |
0.04 |
|
R5323:Shprh
|
UTSW |
10 |
11,170,297 (GRCm38) |
splice site |
probably null |
|
|
R5450:Shprh
|
UTSW |
10 |
11,212,330 (GRCm38) |
missense |
possibly damaging |
0.70 |
|
R5872:Shprh
|
UTSW |
10 |
11,188,073 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6030:Shprh
|
UTSW |
10 |
11,151,991 (GRCm38) |
missense |
probably benign |
0.37 |
|
R6030:Shprh
|
UTSW |
10 |
11,151,991 (GRCm38) |
missense |
probably benign |
0.37 |
|
R6392:Shprh
|
UTSW |
10 |
11,178,741 (GRCm38) |
nonsense |
probably null |
|
|
R6416:Shprh
|
UTSW |
10 |
11,167,873 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6470:Shprh
|
UTSW |
10 |
11,171,937 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R6513:Shprh
|
UTSW |
10 |
11,186,893 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6530:Shprh
|
UTSW |
10 |
11,194,267 (GRCm38) |
missense |
probably benign |
0.02 |
|
R6678:Shprh
|
UTSW |
10 |
11,166,545 (GRCm38) |
missense |
probably benign |
0.16 |
|
R6757:Shprh
|
UTSW |
10 |
11,181,508 (GRCm38) |
splice site |
probably null |
|
|
R6971:Shprh
|
UTSW |
10 |
11,166,693 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7158:Shprh
|
UTSW |
10 |
11,166,730 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R7582:Shprh
|
UTSW |
10 |
11,164,705 (GRCm38) |
missense |
probably benign |
|
|
R7757:Shprh
|
UTSW |
10 |
11,162,180 (GRCm38) |
missense |
probably benign |
0.30 |
|
R7812:Shprh
|
UTSW |
10 |
11,151,991 (GRCm38) |
missense |
probably benign |
|
|
R8061:Shprh
|
UTSW |
10 |
11,212,333 (GRCm38) |
missense |
possibly damaging |
0.71 |
|
R8082:Shprh
|
UTSW |
10 |
11,151,811 (GRCm38) |
missense |
probably benign |
0.22 |
|
R8116:Shprh
|
UTSW |
10 |
11,213,461 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R8390:Shprh
|
UTSW |
10 |
11,187,983 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R8445:Shprh
|
UTSW |
10 |
11,181,569 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R8530:Shprh
|
UTSW |
10 |
11,151,934 (GRCm38) |
missense |
probably benign |
0.37 |
|
R8759:Shprh
|
UTSW |
10 |
11,157,164 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R8937:Shprh
|
UTSW |
10 |
11,185,437 (GRCm38) |
missense |
possibly damaging |
0.60 |
|
R8995:Shprh
|
UTSW |
10 |
11,164,830 (GRCm38) |
nonsense |
probably null |
|
|
R9053:Shprh
|
UTSW |
10 |
11,154,702 (GRCm38) |
missense |
probably benign |
0.04 |
|
R9131:Shprh
|
UTSW |
10 |
11,162,845 (GRCm38) |
missense |
possibly damaging |
0.58 |
|
R9176:Shprh
|
UTSW |
10 |
11,160,576 (GRCm38) |
missense |
probably benign |
0.02 |
|
R9391:Shprh
|
UTSW |
10 |
11,162,889 (GRCm38) |
missense |
probably benign |
0.05 |
|
R9423:Shprh
|
UTSW |
10 |
11,205,263 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9563:Shprh
|
UTSW |
10 |
11,166,491 (GRCm38) |
nonsense |
probably null |
|
|
R9668:Shprh
|
UTSW |
10 |
11,206,332 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R9709:Shprh
|
UTSW |
10 |
11,162,830 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R9718:Shprh
|
UTSW |
10 |
11,213,504 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9750:Shprh
|
UTSW |
10 |
11,164,460 (GRCm38) |
missense |
probably damaging |
0.98 |
|
RF012:Shprh
|
UTSW |
10 |
11,164,841 (GRCm38) |
missense |
probably benign |
0.02 |
|
V8831:Shprh
|
UTSW |
10 |
11,186,862 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1176:Shprh
|
UTSW |
10 |
11,186,447 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1176:Shprh
|
UTSW |
10 |
11,164,553 (GRCm38) |
missense |
probably benign |
|
|
Z1177:Shprh
|
UTSW |
10 |
11,151,762 (GRCm38) |
frame shift |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- GTATTTGCCCAATACACACAGTTTG -3'
(R):5'- GCATGCAGCTCCTGATACTAAATG -3'
Sequencing Primer
(F):5'- ACAGTTTGTGTGTTTTTCTGTGTG -3'
(R):5'- CTGATACTAAATGACCTGCACGCTTG -3'
|
| Posted On |
2020-01-23 |
Incidental Mutation