Incidental Mutation 'R0675:Zfhx2'
| ID |
61625 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Zfhx2
|
| Ensembl Gene |
ENSMUSG00000040721 |
| Gene Name |
zinc finger homeobox 2 |
| Synonyms |
zfh-5 |
| MMRRC Submission |
038860-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.354)
|
| Stock # |
R0675 (G1)
|
| Quality Score |
173 |
|
Status
|
Validated
|
| Chromosome |
14 |
| Chromosomal Location |
55297719-55329781 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 55300620 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Alanine
at position 2377
(V2377A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000045156
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000036328]
[ENSMUST00000183822]
[ENSMUST00000185121]
|
| AlphaFold |
Q2MHN3 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000036328
AA Change: V2377A
PolyPhen 2
Score 0.987 (Sensitivity: 0.73; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000045156
Gene: ENSMUSG00000040721
AA Change: V2377A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
22 |
42 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
230 |
252 |
1.43e1 |
SMART |
|
low complexity region
|
333 |
345 |
N/A |
INTRINSIC |
|
low complexity region
|
428 |
439 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
446 |
469 |
8.94e-3 |
SMART |
|
ZnF_U1
|
498 |
532 |
6.98e-1 |
SMART |
|
ZnF_C2H2
|
501 |
525 |
3.21e-4 |
SMART |
|
ZnF_U1
|
560 |
594 |
1.36e0 |
SMART |
|
ZnF_C2H2
|
563 |
587 |
3.29e-1 |
SMART |
|
low complexity region
|
597 |
623 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
752 |
776 |
6.4e0 |
SMART |
|
ZnF_C2H2
|
815 |
839 |
2.02e-1 |
SMART |
|
ZnF_U1
|
861 |
895 |
1.78e1 |
SMART |
|
ZnF_C2H2
|
864 |
888 |
5.34e-1 |
SMART |
|
ZnF_C2H2
|
974 |
997 |
1.51e1 |
SMART |
|
ZnF_C2H2
|
1003 |
1026 |
1.51e0 |
SMART |
|
low complexity region
|
1087 |
1103 |
N/A |
INTRINSIC |
|
low complexity region
|
1106 |
1126 |
N/A |
INTRINSIC |
|
ZnF_U1
|
1182 |
1216 |
3.42e0 |
SMART |
|
ZnF_C2H2
|
1185 |
1209 |
8.22e-2 |
SMART |
|
ZnF_U1
|
1239 |
1273 |
3.73e0 |
SMART |
|
ZnF_C2H2
|
1242 |
1266 |
6.67e-2 |
SMART |
|
low complexity region
|
1277 |
1304 |
N/A |
INTRINSIC |
|
low complexity region
|
1314 |
1326 |
N/A |
INTRINSIC |
|
low complexity region
|
1332 |
1346 |
N/A |
INTRINSIC |
|
low complexity region
|
1349 |
1359 |
N/A |
INTRINSIC |
|
low complexity region
|
1379 |
1400 |
N/A |
INTRINSIC |
|
low complexity region
|
1457 |
1465 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1474 |
1497 |
5.34e0 |
SMART |
|
low complexity region
|
1522 |
1531 |
N/A |
INTRINSIC |
|
low complexity region
|
1542 |
1554 |
N/A |
INTRINSIC |
|
low complexity region
|
1562 |
1583 |
N/A |
INTRINSIC |
|
HOX
|
1589 |
1651 |
1.97e-16 |
SMART |
|
low complexity region
|
1656 |
1665 |
N/A |
INTRINSIC |
|
coiled coil region
|
1693 |
1723 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1761 |
1783 |
2.53e-2 |
SMART |
|
low complexity region
|
1837 |
1847 |
N/A |
INTRINSIC |
|
HOX
|
1851 |
1913 |
2.34e-18 |
SMART |
|
low complexity region
|
1984 |
1995 |
N/A |
INTRINSIC |
|
low complexity region
|
2001 |
2051 |
N/A |
INTRINSIC |
|
HOX
|
2058 |
2120 |
1.52e-17 |
SMART |
|
ZnF_U1
|
2136 |
2170 |
1.09e1 |
SMART |
|
ZnF_C2H2
|
2139 |
2163 |
5.4e1 |
SMART |
|
low complexity region
|
2328 |
2354 |
N/A |
INTRINSIC |
|
low complexity region
|
2385 |
2426 |
N/A |
INTRINSIC |
|
ZnF_U1
|
2482 |
2516 |
8.31e-1 |
SMART |
|
ZnF_C2H2
|
2485 |
2509 |
9.46e0 |
SMART |
|
low complexity region
|
2523 |
2538 |
N/A |
INTRINSIC |
|
low complexity region
|
2553 |
2562 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000176665
|
| SMART Domains |
Protein: ENSMUSP00000134955
Gene: ENSMUSG00000040721
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
13 |
37 |
5.34e-1 |
SMART |
|
ZnF_C2H2
|
133 |
156 |
1.51e1 |
SMART |
|
ZnF_C2H2
|
162 |
185 |
1.51e0 |
SMART |
|
low complexity region
|
246 |
262 |
N/A |
INTRINSIC |
|
low complexity region
|
265 |
285 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
344 |
368 |
8.22e-2 |
SMART |
|
ZnF_C2H2
|
401 |
425 |
6.67e-2 |
SMART |
|
low complexity region
|
436 |
463 |
N/A |
INTRINSIC |
|
low complexity region
|
473 |
485 |
N/A |
INTRINSIC |
|
low complexity region
|
491 |
505 |
N/A |
INTRINSIC |
|
low complexity region
|
508 |
518 |
N/A |
INTRINSIC |
|
low complexity region
|
538 |
559 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000176872
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000183750
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000183822
|
| SMART Domains |
Protein: ENSMUSP00000140371
Gene: ENSMUSG00000045691
| Domain | Start | End | E-Value | Type |
|---|
|
PDB:2JMU|A
|
5 |
64 |
3e-23 |
PDB |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000183993
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000185121
|
| Meta Mutation Damage Score |
0.6467 |
| Coding Region Coverage |
- 1x: 99.4%
- 3x: 98.9%
- 10x: 97.7%
- 20x: 96.1%
|
| Validation Efficiency |
97% (88/91) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 78 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Ablim2 |
C |
T |
5: 36,024,124 (GRCm39) |
|
probably benign |
Het |
| Aire |
T |
C |
10: 77,870,327 (GRCm39) |
|
probably benign |
Het |
| Akap12 |
T |
C |
10: 4,303,315 (GRCm39) |
S42P |
probably benign |
Het |
| Amigo1 |
T |
C |
3: 108,098,985 (GRCm39) |
|
probably benign |
Het |
| Angptl3 |
A |
G |
4: 98,921,499 (GRCm39) |
T206A |
probably benign |
Het |
| Ank1 |
T |
A |
8: 23,600,400 (GRCm39) |
|
probably benign |
Het |
| Ano5 |
A |
T |
7: 51,224,558 (GRCm39) |
T472S |
probably damaging |
Het |
| Arid3c |
T |
C |
4: 41,725,958 (GRCm39) |
D215G |
probably damaging |
Het |
| Cd200 |
T |
C |
16: 45,217,473 (GRCm39) |
I73V |
probably benign |
Het |
| Cd47 |
T |
C |
16: 49,727,162 (GRCm39) |
I318T |
possibly damaging |
Het |
| Cep290 |
A |
G |
10: 100,404,675 (GRCm39) |
|
probably null |
Het |
| Cep350 |
A |
G |
1: 155,835,499 (GRCm39) |
S66P |
possibly damaging |
Het |
| Cfap46 |
C |
T |
7: 139,255,950 (GRCm39) |
C300Y |
probably damaging |
Het |
| Chd1 |
T |
A |
17: 15,978,523 (GRCm39) |
|
probably benign |
Het |
| Chd5 |
C |
A |
4: 152,470,407 (GRCm39) |
T1913K |
probably benign |
Het |
| Cimip3 |
T |
C |
17: 47,724,701 (GRCm39) |
E140G |
probably benign |
Het |
| Clec4b1 |
A |
G |
6: 123,048,405 (GRCm39) |
Y180C |
probably damaging |
Het |
| Cntnap5c |
A |
T |
17: 58,341,990 (GRCm39) |
D227V |
probably damaging |
Het |
| Col19a1 |
C |
G |
1: 24,614,536 (GRCm39) |
|
probably benign |
Het |
| Csmd1 |
A |
T |
8: 16,208,145 (GRCm39) |
M1270K |
probably benign |
Het |
| Cyp2c66 |
T |
A |
19: 39,175,060 (GRCm39) |
F487I |
possibly damaging |
Het |
| Dpp8 |
T |
C |
9: 64,973,784 (GRCm39) |
|
probably benign |
Het |
| Duoxa1 |
A |
T |
2: 122,136,861 (GRCm39) |
|
probably benign |
Het |
| Edil3 |
A |
G |
13: 89,325,399 (GRCm39) |
K263E |
probably damaging |
Het |
| Fat2 |
A |
G |
11: 55,200,035 (GRCm39) |
L1013P |
probably damaging |
Het |
| Fras1 |
T |
C |
5: 96,815,246 (GRCm39) |
|
probably benign |
Het |
| Gab1 |
A |
G |
8: 81,496,297 (GRCm39) |
S668P |
probably damaging |
Het |
| Galnt14 |
T |
C |
17: 73,852,030 (GRCm39) |
T130A |
probably damaging |
Het |
| Gm10192 |
G |
A |
4: 97,071,109 (GRCm39) |
H99Y |
unknown |
Het |
| Gm5592 |
A |
G |
7: 40,938,811 (GRCm39) |
T698A |
possibly damaging |
Het |
| Gm6605 |
C |
A |
7: 38,147,699 (GRCm39) |
|
noncoding transcript |
Het |
| Gsdma3 |
A |
G |
11: 98,522,017 (GRCm39) |
K149R |
probably benign |
Het |
| Igkv4-71 |
A |
G |
6: 69,220,411 (GRCm39) |
S29P |
probably damaging |
Het |
| Igsf10 |
C |
T |
3: 59,236,015 (GRCm39) |
V1389I |
probably benign |
Het |
| Ik |
T |
C |
18: 36,880,386 (GRCm39) |
|
probably benign |
Het |
| Ino80 |
G |
A |
2: 119,213,962 (GRCm39) |
P1203S |
probably damaging |
Het |
| Iqsec2 |
G |
A |
X: 150,987,120 (GRCm39) |
E398K |
possibly damaging |
Het |
| Jmjd6 |
A |
G |
11: 116,731,353 (GRCm39) |
V232A |
probably damaging |
Het |
| Klhdc9 |
G |
A |
1: 171,187,895 (GRCm39) |
T112M |
possibly damaging |
Het |
| Marcks |
A |
G |
10: 37,017,181 (GRCm39) |
|
probably benign |
Het |
| Mctp2 |
T |
A |
7: 71,732,918 (GRCm39) |
T829S |
probably damaging |
Het |
| Mroh2a |
C |
A |
1: 88,156,102 (GRCm39) |
A78E |
probably damaging |
Het |
| Mroh2a |
G |
A |
1: 88,178,064 (GRCm39) |
D1053N |
probably damaging |
Het |
| Mtmr14 |
A |
T |
6: 113,247,608 (GRCm39) |
H518L |
probably damaging |
Het |
| Myo5c |
T |
C |
9: 75,185,571 (GRCm39) |
M978T |
probably benign |
Het |
| Nlrc3 |
T |
C |
16: 3,766,775 (GRCm39) |
I1015V |
probably benign |
Het |
| Nlrp5 |
C |
A |
7: 23,116,842 (GRCm39) |
Q189K |
possibly damaging |
Het |
| Or1e26 |
A |
C |
11: 73,480,078 (GRCm39) |
L162R |
probably damaging |
Het |
| Or2h2c |
G |
C |
17: 37,422,347 (GRCm39) |
L176V |
probably benign |
Het |
| Or51f1d |
A |
G |
7: 102,700,909 (GRCm39) |
I135V |
probably benign |
Het |
| Or8k35 |
T |
C |
2: 86,424,423 (GRCm39) |
I250V |
probably benign |
Het |
| Otof |
T |
A |
5: 30,539,705 (GRCm39) |
Y1051F |
probably benign |
Het |
| Pcdhb14 |
C |
A |
18: 37,581,392 (GRCm39) |
T166K |
possibly damaging |
Het |
| Pla2g4e |
A |
G |
2: 120,030,679 (GRCm39) |
|
probably benign |
Het |
| Polr3gl |
T |
C |
3: 96,489,471 (GRCm39) |
E20G |
probably damaging |
Het |
| Psmd1 |
A |
G |
1: 86,009,761 (GRCm39) |
D295G |
probably benign |
Het |
| Ptpn21 |
C |
A |
12: 98,654,475 (GRCm39) |
A831S |
probably benign |
Het |
| Pwwp3a |
T |
A |
10: 80,065,914 (GRCm39) |
V56E |
probably damaging |
Het |
| Rd3l |
T |
C |
12: 111,946,596 (GRCm39) |
D60G |
probably benign |
Het |
| Rif1 |
GCCACCA |
GCCA |
2: 52,000,336 (GRCm39) |
|
probably benign |
Het |
| Rnf213 |
A |
G |
11: 119,332,660 (GRCm39) |
D2624G |
probably benign |
Het |
| Sec31a |
T |
C |
5: 100,541,066 (GRCm39) |
D347G |
probably damaging |
Het |
| Sema4g |
G |
A |
19: 44,986,026 (GRCm39) |
R289H |
probably damaging |
Het |
| Sema5b |
C |
T |
16: 35,480,703 (GRCm39) |
T761I |
probably benign |
Het |
| Septin1 |
A |
T |
7: 126,816,171 (GRCm39) |
F86L |
probably damaging |
Het |
| Shank3 |
T |
C |
15: 89,415,591 (GRCm39) |
V627A |
possibly damaging |
Het |
| Slc25a46 |
C |
A |
18: 31,742,641 (GRCm39) |
G75V |
probably benign |
Het |
| Slc45a2 |
T |
A |
15: 11,025,864 (GRCm39) |
Y405N |
probably damaging |
Het |
| Spidr |
T |
C |
16: 15,855,498 (GRCm39) |
E339G |
probably damaging |
Het |
| Sptbn1 |
A |
T |
11: 30,067,903 (GRCm39) |
H1770Q |
probably damaging |
Het |
| Srgap1 |
T |
C |
10: 121,628,140 (GRCm39) |
Y944C |
probably damaging |
Het |
| Supt20 |
C |
T |
3: 54,614,390 (GRCm39) |
T169I |
probably damaging |
Het |
| Tie1 |
G |
A |
4: 118,336,966 (GRCm39) |
Q587* |
probably null |
Het |
| Tmem214 |
A |
G |
5: 31,029,169 (GRCm39) |
T203A |
possibly damaging |
Het |
| Tmprss15 |
C |
A |
16: 78,782,838 (GRCm39) |
S742I |
probably damaging |
Het |
| Wdr87-ps |
T |
C |
7: 29,231,942 (GRCm39) |
|
noncoding transcript |
Het |
| Zfp763 |
G |
A |
17: 33,238,774 (GRCm39) |
H124Y |
possibly damaging |
Het |
| Zfp846 |
T |
C |
9: 20,504,853 (GRCm39) |
S238P |
probably benign |
Het |
|
| Other mutations in Zfhx2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00091:Zfhx2
|
APN |
14 |
55,304,022 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL00164:Zfhx2
|
APN |
14 |
55,302,483 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
IGL00235:Zfhx2
|
APN |
14 |
55,300,714 (GRCm39) |
missense |
probably benign |
0.11 |
|
IGL00925:Zfhx2
|
APN |
14 |
55,310,518 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL01025:Zfhx2
|
APN |
14 |
55,301,717 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01061:Zfhx2
|
APN |
14 |
55,311,339 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
IGL01486:Zfhx2
|
APN |
14 |
55,304,547 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01875:Zfhx2
|
APN |
14 |
55,301,372 (GRCm39) |
missense |
unknown |
|
|
IGL01990:Zfhx2
|
APN |
14 |
55,311,047 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02097:Zfhx2
|
APN |
14 |
55,300,351 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02269:Zfhx2
|
APN |
14 |
55,309,393 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02488:Zfhx2
|
APN |
14 |
55,302,560 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
IGL02624:Zfhx2
|
APN |
14 |
55,304,085 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL03087:Zfhx2
|
APN |
14 |
55,310,302 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
G1patch:Zfhx2
|
UTSW |
14 |
55,301,539 (GRCm39) |
nonsense |
probably null |
|
|
PIT4403001:Zfhx2
|
UTSW |
14 |
55,312,437 (GRCm39) |
missense |
probably benign |
|
|
R0148:Zfhx2
|
UTSW |
14 |
55,310,354 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R0323:Zfhx2
|
UTSW |
14 |
55,303,436 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R0328:Zfhx2
|
UTSW |
14 |
55,309,445 (GRCm39) |
missense |
probably benign |
|
|
R0348:Zfhx2
|
UTSW |
14 |
55,300,965 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0442:Zfhx2
|
UTSW |
14 |
55,304,357 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R0533:Zfhx2
|
UTSW |
14 |
55,301,547 (GRCm39) |
missense |
probably benign |
0.23 |
|
R0561:Zfhx2
|
UTSW |
14 |
55,303,346 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0627:Zfhx2
|
UTSW |
14 |
55,302,784 (GRCm39) |
missense |
probably benign |
|
|
R0659:Zfhx2
|
UTSW |
14 |
55,311,258 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R1301:Zfhx2
|
UTSW |
14 |
55,300,854 (GRCm39) |
missense |
probably benign |
0.32 |
|
R1563:Zfhx2
|
UTSW |
14 |
55,302,545 (GRCm39) |
missense |
probably benign |
0.33 |
|
R1607:Zfhx2
|
UTSW |
14 |
55,300,442 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1694:Zfhx2
|
UTSW |
14 |
55,311,401 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R1710:Zfhx2
|
UTSW |
14 |
55,303,455 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R1773:Zfhx2
|
UTSW |
14 |
55,310,348 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R1879:Zfhx2
|
UTSW |
14 |
55,310,206 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R1879:Zfhx2
|
UTSW |
14 |
55,303,074 (GRCm39) |
missense |
probably benign |
0.32 |
|
R1933:Zfhx2
|
UTSW |
14 |
55,312,695 (GRCm39) |
start gained |
probably benign |
|
|
R1944:Zfhx2
|
UTSW |
14 |
55,312,189 (GRCm39) |
missense |
probably benign |
0.18 |
|
R2888:Zfhx2
|
UTSW |
14 |
55,302,260 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R2889:Zfhx2
|
UTSW |
14 |
55,302,260 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R2915:Zfhx2
|
UTSW |
14 |
55,302,014 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3971:Zfhx2
|
UTSW |
14 |
55,311,932 (GRCm39) |
missense |
probably benign |
0.33 |
|
R4082:Zfhx2
|
UTSW |
14 |
55,302,662 (GRCm39) |
missense |
probably benign |
|
|
R4134:Zfhx2
|
UTSW |
14 |
55,302,600 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4231:Zfhx2
|
UTSW |
14 |
55,310,991 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R4675:Zfhx2
|
UTSW |
14 |
55,304,678 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4764:Zfhx2
|
UTSW |
14 |
55,304,372 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R4866:Zfhx2
|
UTSW |
14 |
55,302,993 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R4940:Zfhx2
|
UTSW |
14 |
55,303,891 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R5125:Zfhx2
|
UTSW |
14 |
55,312,232 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5178:Zfhx2
|
UTSW |
14 |
55,312,232 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5554:Zfhx2
|
UTSW |
14 |
55,301,774 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5689:Zfhx2
|
UTSW |
14 |
55,311,360 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R5768:Zfhx2
|
UTSW |
14 |
55,311,822 (GRCm39) |
missense |
probably benign |
|
|
R5792:Zfhx2
|
UTSW |
14 |
55,304,303 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R5834:Zfhx2
|
UTSW |
14 |
55,310,787 (GRCm39) |
nonsense |
probably null |
|
|
R5895:Zfhx2
|
UTSW |
14 |
55,303,348 (GRCm39) |
missense |
probably benign |
|
|
R5999:Zfhx2
|
UTSW |
14 |
55,311,462 (GRCm39) |
missense |
probably benign |
|
|
R6025:Zfhx2
|
UTSW |
14 |
55,302,665 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6106:Zfhx2
|
UTSW |
14 |
55,305,767 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6135:Zfhx2
|
UTSW |
14 |
55,311,653 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R6186:Zfhx2
|
UTSW |
14 |
55,300,617 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6379:Zfhx2
|
UTSW |
14 |
55,311,795 (GRCm39) |
missense |
probably benign |
|
|
R6725:Zfhx2
|
UTSW |
14 |
55,301,539 (GRCm39) |
nonsense |
probably null |
|
|
R7089:Zfhx2
|
UTSW |
14 |
55,303,229 (GRCm39) |
missense |
probably benign |
0.33 |
|
R7383:Zfhx2
|
UTSW |
14 |
55,305,710 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7470:Zfhx2
|
UTSW |
14 |
55,304,207 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R7606:Zfhx2
|
UTSW |
14 |
55,304,120 (GRCm39) |
missense |
probably benign |
0.12 |
|
R7607:Zfhx2
|
UTSW |
14 |
55,303,688 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R7698:Zfhx2
|
UTSW |
14 |
55,300,306 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7730:Zfhx2
|
UTSW |
14 |
55,304,357 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R8142:Zfhx2
|
UTSW |
14 |
55,310,895 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R8188:Zfhx2
|
UTSW |
14 |
55,301,898 (GRCm39) |
missense |
probably benign |
0.18 |
|
R8212:Zfhx2
|
UTSW |
14 |
55,310,373 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R8264:Zfhx2
|
UTSW |
14 |
55,302,969 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R8331:Zfhx2
|
UTSW |
14 |
55,309,444 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8369:Zfhx2
|
UTSW |
14 |
55,304,201 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8371:Zfhx2
|
UTSW |
14 |
55,301,549 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8383:Zfhx2
|
UTSW |
14 |
55,311,528 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R8415:Zfhx2
|
UTSW |
14 |
55,308,079 (GRCm39) |
missense |
probably benign |
|
|
R8441:Zfhx2
|
UTSW |
14 |
55,303,985 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R8466:Zfhx2
|
UTSW |
14 |
55,310,353 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R8504:Zfhx2
|
UTSW |
14 |
55,303,243 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8708:Zfhx2
|
UTSW |
14 |
55,312,509 (GRCm39) |
missense |
probably benign |
|
|
R8804:Zfhx2
|
UTSW |
14 |
55,312,191 (GRCm39) |
missense |
probably benign |
0.18 |
|
R8913:Zfhx2
|
UTSW |
14 |
55,309,543 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8952:Zfhx2
|
UTSW |
14 |
55,310,207 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R9057:Zfhx2
|
UTSW |
14 |
55,310,027 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R9060:Zfhx2
|
UTSW |
14 |
55,311,803 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9197:Zfhx2
|
UTSW |
14 |
55,312,179 (GRCm39) |
nonsense |
probably null |
|
|
R9622:Zfhx2
|
UTSW |
14 |
55,303,483 (GRCm39) |
missense |
probably benign |
0.18 |
|
R9623:Zfhx2
|
UTSW |
14 |
55,302,191 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9775:Zfhx2
|
UTSW |
14 |
55,304,562 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9780:Zfhx2
|
UTSW |
14 |
55,312,494 (GRCm39) |
missense |
probably benign |
0.02 |
|
X0065:Zfhx2
|
UTSW |
14 |
55,304,417 (GRCm39) |
missense |
probably benign |
0.33 |
|
Z1088:Zfhx2
|
UTSW |
14 |
55,311,637 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
Z1177:Zfhx2
|
UTSW |
14 |
55,304,439 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
Z1177:Zfhx2
|
UTSW |
14 |
55,303,377 (GRCm39) |
missense |
probably benign |
0.40 |
|
| Predicted Primers |
PCR Primer
(F):5'- GCCGTCAAATGCCATCTTGCAC -3'
(R):5'- CCTGAAAGCATTGAAAGCCACTGTC -3'
Sequencing Primer
(F):5'- AGTAGCGGTGAGTCACATCC -3'
(R):5'- TTGAAAGCCACTGTCCCAGC -3'
|
| Posted On |
2013-07-30 |
Incidental Mutation