Mutagenetix > Incidental Mutation

Incidental Mutation 'R8009:Fsip2'

616783

Institutional Source

Beutler Lab

Gene Symbol

Fsip2

Ensembl Gene

ENSMUSG00000075249

Gene Name

fibrous sheath-interacting protein 2

Synonyms

OTTMUSG00000013335

MMRRC Submission

046049-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.174) question?

Stock #

R8009 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

82943634-83008937 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 82988449 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Glutamic Acid to Glycine at position 4842 (E4842G)

Ref Sequence

ENSEMBL: ENSMUSP00000120314 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000143764]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000132967

SMART Domains

Protein: ENSMUSP00000122350
Gene: ENSMUSG00000075249

Domain	Start	End	E-Value	Type
low complexity region	22	38	N/A	INTRINSIC
low complexity region	79	90	N/A	INTRINSIC
low complexity region	381	392	N/A	INTRINSIC
low complexity region	411	430	N/A	INTRINSIC
low complexity region	735	746	N/A	INTRINSIC
low complexity region	953	962	N/A	INTRINSIC

Predicted Effect

possibly damaging
Transcript: ENSMUST00000143764
AA Change: E4842G

PolyPhen 2 Score 0.847 (Sensitivity: 0.83; Specificity: 0.93)

SMART Domains

Protein: ENSMUSP00000120314
Gene: ENSMUSG00000075249
AA Change: E4842G

Domain	Start	End	E-Value	Type
coiled coil region	271	297	N/A	INTRINSIC
low complexity region	544	561	N/A	INTRINSIC
low complexity region	586	597	N/A	INTRINSIC
low complexity region	882	895	N/A	INTRINSIC
low complexity region	925	939	N/A	INTRINSIC
low complexity region	1115	1120	N/A	INTRINSIC
low complexity region	1531	1545	N/A	INTRINSIC
low complexity region	2044	2057	N/A	INTRINSIC
low complexity region	2507	2523	N/A	INTRINSIC
low complexity region	2564	2575	N/A	INTRINSIC
low complexity region	2866	2877	N/A	INTRINSIC
low complexity region	2896	2915	N/A	INTRINSIC
low complexity region	3220	3231	N/A	INTRINSIC
low complexity region	3438	3447	N/A	INTRINSIC
Pfam:FSIP2	4045	4408	3.5e-42	PFAM
Pfam:FSIP2	4375	4613	7.7e-26	PFAM
Pfam:FSIP2	4622	4932	4.3e-17	PFAM
Pfam:FSIP2	4903	5454	7e-27	PFAM
low complexity region	5507	5522	N/A	INTRINSIC
low complexity region	5769	5780	N/A	INTRINSIC
low complexity region	5834	5846	N/A	INTRINSIC
low complexity region	5851	5867	N/A	INTRINSIC
Pfam:FSIP2	5998	6867	N/A	PFAM
low complexity region	6977	6990	N/A	INTRINSIC

Coding Region Coverage

1x: 100.0%
3x: 100.0%
10x: 99.7%
20x: 99.0%

Validation Efficiency

100% (54/54)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein associated with the sperm fibrous sheath. Genes encoding most of the fibrous-sheath associated proteins genes are transcribed only during the postmeiotic period of spermatogenesis. The protein encoded by this gene is specific to spermatogenic cells. Copy number variation in this gene may be associated with testicular germ cell tumors. Pseudogenes associated with this gene are reported on chromosomes 2 and X. [provided by RefSeq, Aug 2016]

Allele List at MGI

Other mutations in this stock

Total: 54 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abcb1b	T	A	5: 8,828,870 (GRCm38)	N751K	possibly damaging	Het
Akap13	G	A	7: 75,730,465 (GRCm38)	R462H	probably damaging	Het
Baz1a	A	T	12: 54,895,031 (GRCm38)	Y1466*	probably null	Het
Casc4	T	C	2: 121,906,761 (GRCm38)	V261A	probably benign	Het
Ccng1	G	A	11: 40,751,269 (GRCm38)	H229Y	probably benign	Het
Cenpn	C	A	8: 116,937,237 (GRCm38)	T256N	probably benign	Het
Ciart	A	G	3: 95,881,317 (GRCm38)	V70A	possibly damaging	Het
Clcc1	A	G	3: 108,661,458 (GRCm38)	N36S	probably damaging	Het
Dmrt1	T	A	19: 25,545,881 (GRCm38)	S199T	possibly damaging	Het
Dmrt3	T	C	19: 25,610,908 (GRCm38)	V37A	possibly damaging	Het
Dock1	T	A	7: 134,745,057 (GRCm38)	D239E	possibly damaging	Het
Dyrk3	A	G	1: 131,136,258 (GRCm38)		probably null	Het
Esyt1	T	C	10: 128,511,485 (GRCm38)	E1057G	probably benign	Het
Gadd45b	G	A	10: 80,931,150 (GRCm38)	V90I	probably benign	Het
Gfi1	T	A	5: 107,723,801 (GRCm38)	H79L	probably damaging	Het
Idh2	T	C	7: 80,098,253 (GRCm38)	H233R	probably benign	Het
Itsn2	G	A	12: 4,664,553 (GRCm38)	A950T	probably benign	Het
Kcna5	A	G	6: 126,533,554 (GRCm38)	L537P	probably benign	Het
Krtap5-4	C	T	7: 142,303,934 (GRCm38)	Q114*	probably null	Het
Loxl3	T	C	6: 83,050,809 (GRCm38)	F734S	possibly damaging	Het
Lpcat1	C	T	13: 73,511,379 (GRCm38)	T420I	probably damaging	Het
Lrch3	A	T	16: 33,005,713 (GRCm38)	D720V	possibly damaging	Het
Lrrk1	T	C	7: 66,265,474 (GRCm38)	D1622G	possibly damaging	Het
Meioc	G	C	11: 102,676,743 (GRCm38)	A788P	probably damaging	Het
Mmp1a	A	T	9: 7,467,235 (GRCm38)	T271S	possibly damaging	Het
Nrp2	C	T	1: 62,745,408 (GRCm38)	R239C	probably damaging	Het
Ntrk3	T	A	7: 78,453,328 (GRCm38)	D408V	probably benign	Het
Odf1	A	G	15: 38,226,596 (GRCm38)	I247V	unknown	Het
Olfr1089	A	G	2: 86,733,504 (GRCm38)	L36P	probably damaging	Het
Olfr126	A	T	17: 37,850,802 (GRCm38)	D70V	probably damaging	Het
Pcsk1	T	C	13: 75,126,839 (GRCm38)	S516P	probably benign	Het
Phactr3	A	C	2: 178,332,944 (GRCm38)	R523S	probably damaging	Het
Pikfyve	A	G	1: 65,255,134 (GRCm38)	D1411G	probably damaging	Het
Ppcs	A	T	4: 119,419,065 (GRCm38)	S281T	probably benign	Het
Prkcg	A	G	7: 3,314,192 (GRCm38)	D294G	probably benign	Het
Psg28	T	A	7: 18,422,997 (GRCm38)	I438L	probably damaging	Het
Pspc1	G	A	14: 56,771,847 (GRCm38)	Q177*	probably null	Het
Rbm33	G	A	5: 28,394,608 (GRCm38)	G185R		Het
Rps6ka5	T	C	12: 100,577,789 (GRCm38)	E350G	probably damaging	Het
Satb2	A	G	1: 56,871,758 (GRCm38)	S243P	probably benign	Het
Serinc5	T	C	13: 92,661,191 (GRCm38)		probably null	Het
Sgce	T	C	6: 4,691,636 (GRCm38)	D313G	probably damaging	Het
Sntg1	C	T	1: 8,363,570 (GRCm38)	V486I	probably damaging	Het
Stxbp5	A	G	10: 9,816,302 (GRCm38)	V366A	probably damaging	Het
Tep1	A	G	14: 50,824,230 (GRCm38)	S2610P	possibly damaging	Het
Tlr3	G	A	8: 45,400,782 (GRCm38)	T167M	not run	Het
Tmem200a	A	G	10: 25,994,006 (GRCm38)	S122P	probably damaging	Het
Tmprss15	C	T	16: 79,090,863 (GRCm38)	V19M	probably damaging	Het
Tnks2	T	A	19: 36,852,501 (GRCm38)	M194K	probably benign	Het
Trav14d-3-dv8	A	C	14: 53,078,767 (GRCm38)	Q28P	probably damaging	Het
Trpm5	T	C	7: 143,080,369 (GRCm38)	E700G	probably benign	Het
Ubqln3	T	A	7: 104,142,590 (GRCm38)	I98L	probably benign	Het
Uso1	A	T	5: 92,166,580 (GRCm38)	E115D	probably benign	Het
Vmn1r28	T	C	6: 58,265,193 (GRCm38)	V7A	probably benign	Het

Other mutations in Fsip2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00094:Fsip2	APN	2	82,990,386 (GRCm38)	missense	probably benign	0.18
IGL00557:Fsip2	APN	2	82,991,313 (GRCm38)	missense	possibly damaging	0.53
IGL01343:Fsip2	APN	2	82,999,819 (GRCm38)	missense	possibly damaging	0.53
IGL01387:Fsip2	APN	2	82,992,982 (GRCm38)	missense	possibly damaging	0.71
IGL01523:Fsip2	APN	2	82,977,519 (GRCm38)	missense	probably benign
IGL01554:Fsip2	APN	2	82,977,278 (GRCm38)	missense	possibly damaging	0.68
IGL01650:Fsip2	APN	2	82,991,086 (GRCm38)	missense	probably benign	0.33
IGL01809:Fsip2	APN	2	82,978,347 (GRCm38)	missense	possibly damaging	0.80
IGL01826:Fsip2	APN	2	82,982,639 (GRCm38)	missense	probably benign	0.18
IGL01830:Fsip2	APN	2	82,984,929 (GRCm38)	missense	probably benign
IGL01918:Fsip2	APN	2	82,992,138 (GRCm38)	missense	possibly damaging	0.71
IGL01932:Fsip2	APN	2	82,994,005 (GRCm38)	missense	possibly damaging	0.71
IGL01989:Fsip2	APN	2	82,993,867 (GRCm38)	missense	probably damaging	0.99
IGL02096:Fsip2	APN	2	82,991,860 (GRCm38)	missense	possibly damaging	0.85
IGL02153:Fsip2	APN	2	82,978,721 (GRCm38)	missense	probably benign
IGL02155:Fsip2	APN	2	82,998,352 (GRCm38)	missense	probably benign
IGL02219:Fsip2	APN	2	82,977,830 (GRCm38)	missense	probably benign	0.07
IGL02248:Fsip2	APN	2	82,982,772 (GRCm38)	missense	possibly damaging	0.73
IGL02316:Fsip2	APN	2	82,978,793 (GRCm38)	missense	probably benign
IGL02478:Fsip2	APN	2	82,984,392 (GRCm38)	missense	probably benign	0.00
IGL02504:Fsip2	APN	2	82,978,855 (GRCm38)	missense	possibly damaging	0.83
IGL02572:Fsip2	APN	2	82,992,003 (GRCm38)	missense	probably benign	0.32
IGL02625:Fsip2	APN	2	82,949,492 (GRCm38)	missense	probably benign	0.00
IGL02665:Fsip2	APN	2	82,993,063 (GRCm38)	missense	probably damaging	1.00
IGL02668:Fsip2	APN	2	82,998,318 (GRCm38)	missense	probably benign	0.06
IGL02676:Fsip2	APN	2	82,982,157 (GRCm38)	missense	possibly damaging	0.53
IGL02717:Fsip2	APN	2	82,951,026 (GRCm38)	splice site	probably benign
IGL02805:Fsip2	APN	2	82,993,495 (GRCm38)	missense	probably benign	0.01
IGL02943:Fsip2	APN	2	82,992,357 (GRCm38)	missense	probably benign	0.32
IGL02965:Fsip2	APN	2	82,983,054 (GRCm38)	missense	probably benign	0.33
IGL03001:Fsip2	APN	2	82,990,624 (GRCm38)	intron	probably benign
IGL03076:Fsip2	APN	2	82,982,138 (GRCm38)	missense	possibly damaging	0.96
IGL03229:Fsip2	APN	2	82,978,076 (GRCm38)	missense	possibly damaging	0.86
IGL03353:Fsip2	APN	2	82,977,393 (GRCm38)	missense	possibly damaging	0.85
IGL03401:Fsip2	APN	2	82,990,470 (GRCm38)	missense	probably benign
bubblegum	UTSW	2	82,992,840 (GRCm38)	missense	probably benign	0.16
Dao	UTSW	2	82,993,150 (GRCm38)	missense	probably damaging	0.97
engulf	UTSW	2	82,984,776 (GRCm38)	missense	probably damaging	0.98
envelope	UTSW	2	82,980,741 (GRCm38)	missense	probably benign	0.07
gladius	UTSW	2	82,981,949 (GRCm38)	missense	possibly damaging	0.68
glove	UTSW	2	82,978,394 (GRCm38)	missense	possibly damaging	0.85
Katana	UTSW	2	82,989,516 (GRCm38)	missense	probably benign	0.07
scarf	UTSW	2	82,986,891 (GRCm38)	missense	probably benign
Sock	UTSW	2	82,998,180 (GRCm38)	missense	probably benign	0.00
swaddle	UTSW	2	82,983,428 (GRCm38)	missense	possibly damaging	0.93
wrap	UTSW	2	82,986,820 (GRCm38)	missense	probably benign	0.04
Wrapper	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
D4186:Fsip2	UTSW	2	82,988,412 (GRCm38)	missense	probably benign	0.32
FR4976:Fsip2	UTSW	2	82,984,365 (GRCm38)	critical splice acceptor site	probably benign
FR4976:Fsip2	UTSW	2	82,984,362 (GRCm38)	critical splice acceptor site	probably benign
PIT4382001:Fsip2	UTSW	2	82,990,852 (GRCm38)	missense	possibly damaging	0.86
R0017:Fsip2	UTSW	2	82,992,072 (GRCm38)	missense	probably damaging	0.98
R0017:Fsip2	UTSW	2	82,992,072 (GRCm38)	missense	probably damaging	0.98
R0021:Fsip2	UTSW	2	82,999,857 (GRCm38)	splice site	probably benign
R0054:Fsip2	UTSW	2	82,986,955 (GRCm38)	missense	possibly damaging	0.85
R0054:Fsip2	UTSW	2	82,986,955 (GRCm38)	missense	possibly damaging	0.85
R0054:Fsip2	UTSW	2	82,976,608 (GRCm38)	missense	probably damaging	0.96
R0104:Fsip2	UTSW	2	82,978,973 (GRCm38)	missense	possibly damaging	0.91
R0104:Fsip2	UTSW	2	82,978,973 (GRCm38)	missense	possibly damaging	0.91
R0127:Fsip2	UTSW	2	82,984,925 (GRCm38)	missense	probably benign	0.28
R0131:Fsip2	UTSW	2	82,991,121 (GRCm38)	missense	probably benign
R0149:Fsip2	UTSW	2	82,975,505 (GRCm38)	missense	possibly damaging	0.93
R0167:Fsip2	UTSW	2	82,980,807 (GRCm38)	missense	possibly damaging	0.53
R0190:Fsip2	UTSW	2	82,985,177 (GRCm38)	missense	possibly damaging	0.73
R0323:Fsip2	UTSW	2	82,985,896 (GRCm38)	missense	probably benign	0.33
R0358:Fsip2	UTSW	2	82,983,333 (GRCm38)	missense	possibly damaging	0.56
R0361:Fsip2	UTSW	2	82,975,505 (GRCm38)	missense	possibly damaging	0.93
R0369:Fsip2	UTSW	2	82,984,564 (GRCm38)	missense	probably benign	0.33
R0394:Fsip2	UTSW	2	82,991,075 (GRCm38)	missense	possibly damaging	0.70
R0532:Fsip2	UTSW	2	82,977,785 (GRCm38)	missense	probably benign	0.33
R0595:Fsip2	UTSW	2	82,946,952 (GRCm38)	missense	probably damaging	0.99
R0613:Fsip2	UTSW	2	82,993,795 (GRCm38)	missense	probably damaging	0.99
R0614:Fsip2	UTSW	2	82,977,533 (GRCm38)	missense	probably benign	0.15
R0619:Fsip2	UTSW	2	82,944,140 (GRCm38)	missense	probably damaging	1.00
R0626:Fsip2	UTSW	2	82,988,958 (GRCm38)	missense	probably benign	0.06
R0644:Fsip2	UTSW	2	82,976,897 (GRCm38)	missense	probably benign	0.02
R0661:Fsip2	UTSW	2	82,986,169 (GRCm38)	missense	possibly damaging	0.92
R0680:Fsip2	UTSW	2	82,991,359 (GRCm38)	missense	possibly damaging	0.73
R0688:Fsip2	UTSW	2	82,982,339 (GRCm38)	missense	probably benign	0.18
R0881:Fsip2	UTSW	2	82,986,273 (GRCm38)	missense	possibly damaging	0.52
R0919:Fsip2	UTSW	2	82,985,484 (GRCm38)	missense	possibly damaging	0.53
R0973:Fsip2	UTSW	2	82,977,092 (GRCm38)	missense	probably benign	0.05
R0973:Fsip2	UTSW	2	82,977,092 (GRCm38)	missense	probably benign	0.05
R0974:Fsip2	UTSW	2	82,977,092 (GRCm38)	missense	probably benign	0.05
R0976:Fsip2	UTSW	2	82,998,031 (GRCm38)	missense	possibly damaging	0.92
R1025:Fsip2	UTSW	2	82,989,436 (GRCm38)	nonsense	probably null
R1026:Fsip2	UTSW	2	82,988,461 (GRCm38)	missense	possibly damaging	0.52
R1140:Fsip2	UTSW	2	82,975,034 (GRCm38)	missense	probably damaging	0.99
R1170:Fsip2	UTSW	2	82,991,500 (GRCm38)	missense	possibly damaging	0.72
R1180:Fsip2	UTSW	2	82,975,226 (GRCm38)	missense	probably damaging	0.99
R1188:Fsip2	UTSW	2	82,975,017 (GRCm38)	missense	possibly damaging	0.96
R1226:Fsip2	UTSW	2	82,981,011 (GRCm38)	missense	probably damaging	0.96
R1248:Fsip2	UTSW	2	82,989,763 (GRCm38)	missense	possibly damaging	0.93
R1273:Fsip2	UTSW	2	82,989,408 (GRCm38)	missense	possibly damaging	0.92
R1323:Fsip2	UTSW	2	82,985,752 (GRCm38)	missense	probably damaging	1.00
R1323:Fsip2	UTSW	2	82,985,752 (GRCm38)	missense	probably damaging	1.00
R1356:Fsip2	UTSW	2	82,989,745 (GRCm38)	missense	probably benign	0.38
R1413:Fsip2	UTSW	2	82,988,418 (GRCm38)	missense	possibly damaging	0.93
R1430:Fsip2	UTSW	2	82,998,063 (GRCm38)	missense	possibly damaging	0.71
R1475:Fsip2	UTSW	2	82,987,195 (GRCm38)	missense	probably damaging	0.99
R1489:Fsip2	UTSW	2	82,979,811 (GRCm38)	missense	probably benign
R1520:Fsip2	UTSW	2	82,980,714 (GRCm38)	missense	possibly damaging	0.96
R1543:Fsip2	UTSW	2	82,981,587 (GRCm38)	missense	possibly damaging	0.91
R1581:Fsip2	UTSW	2	82,986,282 (GRCm38)	missense	probably damaging	0.98
R1590:Fsip2	UTSW	2	82,982,787 (GRCm38)	missense	probably benign	0.26
R1646:Fsip2	UTSW	2	82,978,517 (GRCm38)	missense	probably benign	0.07
R1678:Fsip2	UTSW	2	82,986,345 (GRCm38)	missense	probably benign
R1700:Fsip2	UTSW	2	82,991,737 (GRCm38)	missense	probably benign	0.33
R1717:Fsip2	UTSW	2	82,974,945 (GRCm38)	missense	possibly damaging	0.68
R1741:Fsip2	UTSW	2	82,989,912 (GRCm38)	missense	probably benign	0.32
R1760:Fsip2	UTSW	2	82,987,711 (GRCm38)	missense	possibly damaging	0.71
R1760:Fsip2	UTSW	2	82,984,896 (GRCm38)	missense	probably benign	0.07
R1760:Fsip2	UTSW	2	82,999,841 (GRCm38)	missense	possibly damaging	0.85
R1789:Fsip2	UTSW	2	82,977,562 (GRCm38)	missense	probably benign	0.00
R1850:Fsip2	UTSW	2	82,984,589 (GRCm38)	missense	possibly damaging	0.72
R1854:Fsip2	UTSW	2	82,993,257 (GRCm38)	missense	possibly damaging	0.84
R1888:Fsip2	UTSW	2	82,944,160 (GRCm38)	missense	probably benign	0.04
R1888:Fsip2	UTSW	2	82,944,160 (GRCm38)	missense	probably benign	0.04
R1905:Fsip2	UTSW	2	82,983,428 (GRCm38)	missense	possibly damaging	0.93
R1907:Fsip2	UTSW	2	82,983,428 (GRCm38)	missense	possibly damaging	0.93
R1920:Fsip2	UTSW	2	82,986,820 (GRCm38)	missense	probably benign	0.04
R1921:Fsip2	UTSW	2	82,986,820 (GRCm38)	missense	probably benign	0.04
R1921:Fsip2	UTSW	2	82,980,783 (GRCm38)	nonsense	probably null
R1931:Fsip2	UTSW	2	82,986,733 (GRCm38)	missense	probably damaging	0.99
R1934:Fsip2	UTSW	2	82,980,558 (GRCm38)	missense	possibly damaging	0.91
R1959:Fsip2	UTSW	2	82,991,550 (GRCm38)	missense	probably benign
R1965:Fsip2	UTSW	2	82,992,780 (GRCm38)	missense	possibly damaging	0.86
R1966:Fsip2	UTSW	2	82,992,780 (GRCm38)	missense	possibly damaging	0.86
R1983:Fsip2	UTSW	2	82,979,831 (GRCm38)	missense	probably benign
R1988:Fsip2	UTSW	2	82,976,517 (GRCm38)	missense	possibly damaging	0.56
R2016:Fsip2	UTSW	2	82,982,732 (GRCm38)	missense	possibly damaging	0.53
R2017:Fsip2	UTSW	2	82,982,732 (GRCm38)	missense	possibly damaging	0.53
R2026:Fsip2	UTSW	2	82,989,444 (GRCm38)	missense	possibly damaging	0.71
R2034:Fsip2	UTSW	2	82,989,494 (GRCm38)	missense	probably benign	0.43
R2037:Fsip2	UTSW	2	82,978,512 (GRCm38)	missense	probably damaging	0.99
R2070:Fsip2	UTSW	2	82,976,355 (GRCm38)	missense	probably damaging	0.98
R2072:Fsip2	UTSW	2	83,008,815 (GRCm38)	missense	possibly damaging	0.53
R2075:Fsip2	UTSW	2	82,988,579 (GRCm38)	missense	possibly damaging	0.85
R2143:Fsip2	UTSW	2	82,990,271 (GRCm38)	missense	possibly damaging	0.93
R2207:Fsip2	UTSW	2	82,977,479 (GRCm38)	missense	probably benign	0.02
R2256:Fsip2	UTSW	2	82,962,751 (GRCm38)	missense	probably benign	0.07
R2315:Fsip2	UTSW	2	82,975,093 (GRCm38)	missense	probably benign
R2344:Fsip2	UTSW	2	82,989,913 (GRCm38)	missense	possibly damaging	0.71
R2377:Fsip2	UTSW	2	82,976,249 (GRCm38)	missense	probably benign	0.29
R2403:Fsip2	UTSW	2	82,980,720 (GRCm38)	missense	possibly damaging	0.53
R2441:Fsip2	UTSW	2	82,985,341 (GRCm38)	missense	possibly damaging	0.53
R2504:Fsip2	UTSW	2	82,979,610 (GRCm38)	missense	possibly damaging	0.86
R2510:Fsip2	UTSW	2	82,986,438 (GRCm38)	missense	probably benign
R2511:Fsip2	UTSW	2	82,986,438 (GRCm38)	missense	probably benign
R2511:Fsip2	UTSW	2	82,951,657 (GRCm38)	missense	probably damaging	1.00
R2512:Fsip2	UTSW	2	82,978,167 (GRCm38)	missense	probably benign	0.04
R2568:Fsip2	UTSW	2	82,990,431 (GRCm38)	missense	probably benign	0.14
R2656:Fsip2	UTSW	2	82,979,045 (GRCm38)	missense	possibly damaging	0.83
R2883:Fsip2	UTSW	2	82,991,524 (GRCm38)	missense	possibly damaging	0.86
R3417:Fsip2	UTSW	2	82,986,510 (GRCm38)	missense	possibly damaging	0.51
R3431:Fsip2	UTSW	2	82,992,010 (GRCm38)	missense	possibly damaging	0.85
R3441:Fsip2	UTSW	2	82,986,727 (GRCm38)	missense	probably benign	0.00
R3605:Fsip2	UTSW	2	82,984,909 (GRCm38)	missense	probably benign	0.28
R3620:Fsip2	UTSW	2	82,980,258 (GRCm38)	missense	probably benign	0.00
R3621:Fsip2	UTSW	2	82,980,258 (GRCm38)	missense	probably benign	0.00
R3726:Fsip2	UTSW	2	82,988,967 (GRCm38)	missense	possibly damaging	0.84
R3755:Fsip2	UTSW	2	82,978,217 (GRCm38)	missense	probably benign	0.26
R3789:Fsip2	UTSW	2	82,982,714 (GRCm38)	missense	probably damaging	0.96
R3836:Fsip2	UTSW	2	82,950,946 (GRCm38)	missense	probably damaging	1.00
R3844:Fsip2	UTSW	2	82,989,606 (GRCm38)	missense	possibly damaging	0.52
R3846:Fsip2	UTSW	2	82,986,415 (GRCm38)	missense	possibly damaging	0.52
R3861:Fsip2	UTSW	2	82,984,776 (GRCm38)	missense	probably damaging	0.98
R3981:Fsip2	UTSW	2	82,958,662 (GRCm38)	missense	probably benign	0.08
R4014:Fsip2	UTSW	2	82,983,518 (GRCm38)	missense	probably benign
R4042:Fsip2	UTSW	2	82,983,552 (GRCm38)	missense	probably benign	0.02
R4075:Fsip2	UTSW	2	82,982,901 (GRCm38)	missense	probably benign	0.26
R4154:Fsip2	UTSW	2	82,987,069 (GRCm38)	missense	possibly damaging	0.71
R4210:Fsip2	UTSW	2	82,975,149 (GRCm38)	missense	probably damaging	0.99
R4211:Fsip2	UTSW	2	82,975,149 (GRCm38)	missense	probably damaging	0.99
R4327:Fsip2	UTSW	2	82,987,059 (GRCm38)	missense	probably benign	0.25
R4332:Fsip2	UTSW	2	82,977,857 (GRCm38)	missense	probably benign	0.00
R4440:Fsip2	UTSW	2	82,991,206 (GRCm38)	missense	possibly damaging	0.85
R4454:Fsip2	UTSW	2	82,990,776 (GRCm38)	missense	possibly damaging	0.70
R4455:Fsip2	UTSW	2	82,990,776 (GRCm38)	missense	possibly damaging	0.70
R4457:Fsip2	UTSW	2	82,990,776 (GRCm38)	missense	possibly damaging	0.70
R4458:Fsip2	UTSW	2	82,990,776 (GRCm38)	missense	possibly damaging	0.70
R4540:Fsip2	UTSW	2	82,951,665 (GRCm38)	missense	probably benign
R4549:Fsip2	UTSW	2	82,989,628 (GRCm38)	missense	probably damaging	0.99
R4558:Fsip2	UTSW	2	82,984,953 (GRCm38)	missense	possibly damaging	0.73
R4573:Fsip2	UTSW	2	82,986,166 (GRCm38)	missense	possibly damaging	0.71
R4583:Fsip2	UTSW	2	82,978,673 (GRCm38)	missense	probably benign	0.33
R4618:Fsip2	UTSW	2	82,987,759 (GRCm38)	missense	probably benign
R4700:Fsip2	UTSW	2	82,987,029 (GRCm38)	missense	probably benign	0.32
R4716:Fsip2	UTSW	2	82,974,859 (GRCm38)	missense	probably damaging	0.96
R4739:Fsip2	UTSW	2	82,975,353 (GRCm38)	missense	possibly damaging	0.92
R4749:Fsip2	UTSW	2	82,989,285 (GRCm38)	missense	probably benign	0.06
R4791:Fsip2	UTSW	2	82,982,108 (GRCm38)	missense	possibly damaging	0.53
R4793:Fsip2	UTSW	2	82,987,700 (GRCm38)	nonsense	probably null
R4819:Fsip2	UTSW	2	82,988,442 (GRCm38)	missense	probably benign	0.06
R4832:Fsip2	UTSW	2	82,990,171 (GRCm38)	missense	possibly damaging	0.92
R4840:Fsip2	UTSW	2	82,985,471 (GRCm38)	missense	probably benign	0.26
R4840:Fsip2	UTSW	2	82,949,395 (GRCm38)	missense	probably benign	0.01
R4865:Fsip2	UTSW	2	82,990,951 (GRCm38)	missense	possibly damaging	0.86
R4876:Fsip2	UTSW	2	82,974,858 (GRCm38)	missense	possibly damaging	0.91
R4885:Fsip2	UTSW	2	82,988,094 (GRCm38)	missense	probably benign	0.02
R4911:Fsip2	UTSW	2	82,981,493 (GRCm38)	missense	possibly damaging	0.85
R4918:Fsip2	UTSW	2	82,993,770 (GRCm38)	missense	possibly damaging	0.51
R4936:Fsip2	UTSW	2	82,985,040 (GRCm38)	missense	probably benign	0.18
R4950:Fsip2	UTSW	2	82,977,414 (GRCm38)	missense	probably benign	0.03
R4950:Fsip2	UTSW	2	82,946,932 (GRCm38)	missense	probably damaging	0.97
R4959:Fsip2	UTSW	2	82,984,825 (GRCm38)	missense	probably benign	0.00
R4971:Fsip2	UTSW	2	82,985,878 (GRCm38)	missense	probably benign	0.38
R4973:Fsip2	UTSW	2	82,984,825 (GRCm38)	missense	probably benign	0.00
R4976:Fsip2	UTSW	2	82,988,191 (GRCm38)	missense	probably damaging	0.99
R5022:Fsip2	UTSW	2	82,979,429 (GRCm38)	missense	probably benign	0.33
R5027:Fsip2	UTSW	2	82,989,133 (GRCm38)	missense	possibly damaging	0.71
R5030:Fsip2	UTSW	2	82,988,492 (GRCm38)	missense	possibly damaging	0.85
R5048:Fsip2	UTSW	2	82,993,150 (GRCm38)	missense	probably damaging	0.97
R5096:Fsip2	UTSW	2	82,991,116 (GRCm38)	missense	probably benign	0.00
R5097:Fsip2	UTSW	2	82,991,985 (GRCm38)	missense	probably benign
R5119:Fsip2	UTSW	2	82,988,191 (GRCm38)	missense	probably damaging	0.99
R5138:Fsip2	UTSW	2	82,981,424 (GRCm38)	missense	probably benign	0.12
R5152:Fsip2	UTSW	2	82,978,572 (GRCm38)	missense	probably benign	0.43
R5174:Fsip2	UTSW	2	82,980,741 (GRCm38)	missense	probably benign	0.07
R5193:Fsip2	UTSW	2	82,982,994 (GRCm38)	missense	possibly damaging	0.53
R5245:Fsip2	UTSW	2	82,993,161 (GRCm38)	missense	probably benign	0.02
R5282:Fsip2	UTSW	2	82,978,581 (GRCm38)	missense	possibly damaging	0.61
R5323:Fsip2	UTSW	2	82,988,145 (GRCm38)	missense	possibly damaging	0.71
R5326:Fsip2	UTSW	2	82,981,863 (GRCm38)	missense	possibly damaging	0.84
R5378:Fsip2	UTSW	2	82,989,841 (GRCm38)	missense	possibly damaging	0.71
R5380:Fsip2	UTSW	2	82,975,398 (GRCm38)	missense	possibly damaging	0.91
R5396:Fsip2	UTSW	2	82,990,918 (GRCm38)	missense	probably benign	0.00
R5422:Fsip2	UTSW	2	82,982,228 (GRCm38)	missense	probably benign	0.00
R5481:Fsip2	UTSW	2	82,979,886 (GRCm38)	missense	probably benign	0.26
R5482:Fsip2	UTSW	2	82,985,310 (GRCm38)	missense	possibly damaging	0.80
R5513:Fsip2	UTSW	2	82,985,198 (GRCm38)	missense	possibly damaging	0.72
R5513:Fsip2	UTSW	2	82,950,912 (GRCm38)	missense	probably benign	0.07
R5513:Fsip2	UTSW	2	82,950,908 (GRCm38)	missense	probably damaging	1.00
R5536:Fsip2	UTSW	2	82,987,059 (GRCm38)	missense	probably benign	0.25
R5542:Fsip2	UTSW	2	82,981,863 (GRCm38)	missense	possibly damaging	0.84
R5553:Fsip2	UTSW	2	82,962,746 (GRCm38)	missense	probably benign
R5568:Fsip2	UTSW	2	82,986,564 (GRCm38)	missense	probably benign	0.25
R5581:Fsip2	UTSW	2	82,998,128 (GRCm38)	missense	possibly damaging	0.84
R5664:Fsip2	UTSW	2	82,988,095 (GRCm38)	missense	probably benign	0.05
R5672:Fsip2	UTSW	2	82,987,494 (GRCm38)	nonsense	probably null
R5712:Fsip2	UTSW	2	83,008,848 (GRCm38)	missense	possibly damaging	0.73
R5762:Fsip2	UTSW	2	82,977,916 (GRCm38)	missense	probably benign	0.33
R5772:Fsip2	UTSW	2	82,984,740 (GRCm38)	missense	probably benign
R5881:Fsip2	UTSW	2	82,984,441 (GRCm38)	missense	possibly damaging	0.72
R5919:Fsip2	UTSW	2	82,992,609 (GRCm38)	missense	possibly damaging	0.71
R5920:Fsip2	UTSW	2	82,988,508 (GRCm38)	nonsense	probably null
R5934:Fsip2	UTSW	2	82,986,748 (GRCm38)	missense	possibly damaging	0.86
R5938:Fsip2	UTSW	2	82,977,491 (GRCm38)	missense	probably benign	0.00
R5974:Fsip2	UTSW	2	82,963,313 (GRCm38)	missense	possibly damaging	0.68
R5991:Fsip2	UTSW	2	82,990,468 (GRCm38)	missense	probably benign	0.28
R6019:Fsip2	UTSW	2	82,987,939 (GRCm38)	missense	possibly damaging	0.52
R6020:Fsip2	UTSW	2	82,992,127 (GRCm38)	missense	probably damaging	0.99
R6056:Fsip2	UTSW	2	82,985,673 (GRCm38)	missense	probably benign	0.01
R6057:Fsip2	UTSW	2	82,979,433 (GRCm38)	missense	probably damaging	0.99
R6139:Fsip2	UTSW	2	82,991,044 (GRCm38)	missense	possibly damaging	0.85
R6145:Fsip2	UTSW	2	82,993,768 (GRCm38)	missense	possibly damaging	0.71
R6160:Fsip2	UTSW	2	82,987,945 (GRCm38)	nonsense	probably null
R6161:Fsip2	UTSW	2	82,987,257 (GRCm38)	missense	possibly damaging	0.80
R6166:Fsip2	UTSW	2	82,980,727 (GRCm38)	missense	probably benign	0.00
R6187:Fsip2	UTSW	2	82,982,454 (GRCm38)	missense	probably benign	0.33
R6196:Fsip2	UTSW	2	82,989,883 (GRCm38)	missense	possibly damaging	0.71
R6217:Fsip2	UTSW	2	82,988,418 (GRCm38)	missense	possibly damaging	0.93
R6276:Fsip2	UTSW	2	82,980,441 (GRCm38)	missense	possibly damaging	0.91
R6278:Fsip2	UTSW	2	82,988,898 (GRCm38)	missense	probably benign	0.16
R6349:Fsip2	UTSW	2	82,993,072 (GRCm38)	missense	probably benign	0.05
R6351:Fsip2	UTSW	2	82,992,684 (GRCm38)	missense	possibly damaging	0.51
R6401:Fsip2	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
R6404:Fsip2	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
R6405:Fsip2	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
R6437:Fsip2	UTSW	2	82,983,492 (GRCm38)	missense	possibly damaging	0.73
R6478:Fsip2	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
R6479:Fsip2	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
R6480:Fsip2	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
R6481:Fsip2	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
R6521:Fsip2	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
R6529:Fsip2	UTSW	2	82,982,313 (GRCm38)	missense	probably benign
R6621:Fsip2	UTSW	2	82,989,814 (GRCm38)	missense	possibly damaging	0.93
R6639:Fsip2	UTSW	2	82,983,227 (GRCm38)	missense	possibly damaging	0.85
R6649:Fsip2	UTSW	2	82,967,817 (GRCm38)	missense	possibly damaging	0.83
R6714:Fsip2	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
R6714:Fsip2	UTSW	2	82,979,534 (GRCm38)	missense	probably benign	0.01
R6749:Fsip2	UTSW	2	82,978,394 (GRCm38)	missense	possibly damaging	0.85
R6765:Fsip2	UTSW	2	82,986,432 (GRCm38)	missense	probably benign
R6790:Fsip2	UTSW	2	82,990,939 (GRCm38)	missense	possibly damaging	0.53
R6793:Fsip2	UTSW	2	82,989,494 (GRCm38)	missense	probably benign	0.43
R6795:Fsip2	UTSW	2	82,980,959 (GRCm38)	missense	probably benign	0.08
R6818:Fsip2	UTSW	2	82,985,200 (GRCm38)	missense	probably benign	0.04
R6844:Fsip2	UTSW	2	82,983,625 (GRCm38)	missense	possibly damaging	0.72
R6848:Fsip2	UTSW	2	82,982,787 (GRCm38)	missense	probably benign	0.26
R6945:Fsip2	UTSW	2	82,992,840 (GRCm38)	missense	probably benign	0.16
R6950:Fsip2	UTSW	2	82,985,988 (GRCm38)	missense	probably benign	0.03
R6951:Fsip2	UTSW	2	82,981,949 (GRCm38)	missense	possibly damaging	0.68
R6974:Fsip2	UTSW	2	82,978,717 (GRCm38)	missense	probably damaging	0.96
R6987:Fsip2	UTSW	2	82,948,286 (GRCm38)	nonsense	probably null
R6989:Fsip2	UTSW	2	82,976,954 (GRCm38)	missense	probably benign	0.00
R7001:Fsip2	UTSW	2	82,986,925 (GRCm38)	missense	probably damaging	1.00
R7002:Fsip2	UTSW	2	82,989,343 (GRCm38)	missense	possibly damaging	0.86
R7016:Fsip2	UTSW	2	82,990,635 (GRCm38)	missense	probably benign	0.25
R7066:Fsip2	UTSW	2	82,990,891 (GRCm38)	missense	possibly damaging	0.86
R7067:Fsip2	UTSW	2	82,980,734 (GRCm38)	missense	possibly damaging	0.85
R7077:Fsip2	UTSW	2	82,983,152 (GRCm38)	missense	probably benign	0.18
R7099:Fsip2	UTSW	2	82,987,624 (GRCm38)	missense	probably benign
R7126:Fsip2	UTSW	2	82,983,141 (GRCm38)	missense	possibly damaging	0.53
R7156:Fsip2	UTSW	2	82,982,741 (GRCm38)	missense	probably benign	0.00
R7165:Fsip2	UTSW	2	82,981,197 (GRCm38)	missense	possibly damaging	0.77
R7171:Fsip2	UTSW	2	82,986,227 (GRCm38)	nonsense	probably null
R7189:Fsip2	UTSW	2	82,993,237 (GRCm38)	missense	possibly damaging	0.92
R7217:Fsip2	UTSW	2	82,989,068 (GRCm38)	missense	possibly damaging	0.85
R7222:Fsip2	UTSW	2	82,983,671 (GRCm38)	missense	probably benign
R7228:Fsip2	UTSW	2	82,992,307 (GRCm38)	missense	possibly damaging	0.93
R7238:Fsip2	UTSW	2	82,982,140 (GRCm38)	missense	possibly damaging	0.72
R7244:Fsip2	UTSW	2	82,993,263 (GRCm38)	missense	possibly damaging	0.92
R7251:Fsip2	UTSW	2	82,979,081 (GRCm38)	missense	possibly damaging	0.95
R7259:Fsip2	UTSW	2	82,982,130 (GRCm38)	missense	possibly damaging	0.85
R7291:Fsip2	UTSW	2	82,980,519 (GRCm38)	missense	possibly damaging	0.91
R7316:Fsip2	UTSW	2	82,989,691 (GRCm38)	missense	possibly damaging	0.93
R7323:Fsip2	UTSW	2	82,989,516 (GRCm38)	missense	probably benign	0.07
R7335:Fsip2	UTSW	2	82,983,118 (GRCm38)	missense	probably benign
R7343:Fsip2	UTSW	2	82,979,367 (GRCm38)	missense	probably benign	0.07
R7346:Fsip2	UTSW	2	82,998,180 (GRCm38)	missense	probably benign	0.00
R7389:Fsip2	UTSW	2	82,988,796 (GRCm38)	missense	possibly damaging	0.51
R7391:Fsip2	UTSW	2	82,990,319 (GRCm38)	missense	possibly damaging	0.70
R7397:Fsip2	UTSW	2	82,985,257 (GRCm38)	missense	possibly damaging	0.53
R7426:Fsip2	UTSW	2	82,980,097 (GRCm38)	missense	probably damaging	0.98
R7450:Fsip2	UTSW	2	82,951,680 (GRCm38)	missense	probably benign	0.30
R7538:Fsip2	UTSW	2	82,988,550 (GRCm38)	missense	possibly damaging	0.86
R7542:Fsip2	UTSW	2	82,984,852 (GRCm38)	missense	possibly damaging	0.96
R7549:Fsip2	UTSW	2	82,993,993 (GRCm38)	missense	probably damaging	0.99
R7564:Fsip2	UTSW	2	82,989,017 (GRCm38)	missense	probably benign	0.02
R7565:Fsip2	UTSW	2	82,949,512 (GRCm38)	missense	probably damaging	0.97
R7583:Fsip2	UTSW	2	82,975,241 (GRCm38)	missense	probably benign	0.12
R7641:Fsip2	UTSW	2	82,986,912 (GRCm38)	nonsense	probably null
R7655:Fsip2	UTSW	2	82,977,542 (GRCm38)	missense	possibly damaging	0.91
R7656:Fsip2	UTSW	2	82,977,542 (GRCm38)	missense	possibly damaging	0.91
R7665:Fsip2	UTSW	2	82,981,805 (GRCm38)	missense	probably benign	0.03
R7672:Fsip2	UTSW	2	82,990,111 (GRCm38)	missense	possibly damaging	0.93
R7764:Fsip2	UTSW	2	82,980,908 (GRCm38)	missense	possibly damaging	0.93
R7790:Fsip2	UTSW	2	82,988,379 (GRCm38)	missense	probably benign
R7811:Fsip2	UTSW	2	82,998,453 (GRCm38)	missense	possibly damaging	0.93
R7838:Fsip2	UTSW	2	82,976,700 (GRCm38)	missense	probably benign	0.00
R7873:Fsip2	UTSW	2	82,949,512 (GRCm38)	missense	probably damaging	0.97
R7902:Fsip2	UTSW	2	82,977,824 (GRCm38)	missense	possibly damaging	0.72
R7920:Fsip2	UTSW	2	82,951,021 (GRCm38)	missense	possibly damaging	0.94
R7959:Fsip2	UTSW	2	82,985,776 (GRCm38)	missense	possibly damaging	0.51
R8031:Fsip2	UTSW	2	82,986,891 (GRCm38)	missense	probably benign
R8034:Fsip2	UTSW	2	82,989,355 (GRCm38)	missense	possibly damaging	0.92
R8037:Fsip2	UTSW	2	82,985,978 (GRCm38)	missense	possibly damaging	0.72
R8110:Fsip2	UTSW	2	82,958,673 (GRCm38)	missense	probably benign	0.00
R8117:Fsip2	UTSW	2	82,992,952 (GRCm38)	missense	possibly damaging	0.86
R8138:Fsip2	UTSW	2	82,975,797 (GRCm38)	missense	possibly damaging	0.83
R8175:Fsip2	UTSW	2	82,987,677 (GRCm38)	missense	probably benign	0.16
R8175:Fsip2	UTSW	2	82,984,744 (GRCm38)	missense	probably benign	0.06
R8182:Fsip2	UTSW	2	82,976,607 (GRCm38)	missense	probably damaging	0.99
R8206:Fsip2	UTSW	2	82,990,464 (GRCm38)	missense	possibly damaging	0.85
R8229:Fsip2	UTSW	2	82,978,143 (GRCm38)	missense	possibly damaging	0.63
R8239:Fsip2	UTSW	2	82,989,343 (GRCm38)	missense	possibly damaging	0.71
R8245:Fsip2	UTSW	2	82,981,002 (GRCm38)	missense	possibly damaging	0.79
R8303:Fsip2	UTSW	2	82,988,380 (GRCm38)	missense	probably benign	0.00
R8336:Fsip2	UTSW	2	82,990,755 (GRCm38)	missense	possibly damaging	0.53
R8347:Fsip2	UTSW	2	82,987,854 (GRCm38)	missense	probably benign	0.16
R8351:Fsip2	UTSW	2	82,991,895 (GRCm38)	missense	possibly damaging	0.73
R8352:Fsip2	UTSW	2	82,984,593 (GRCm38)	missense	probably benign
R8419:Fsip2	UTSW	2	82,978,619 (GRCm38)	missense	probably damaging	0.96
R8431:Fsip2	UTSW	2	82,981,566 (GRCm38)	missense	probably damaging	1.00
R8439:Fsip2	UTSW	2	82,977,086 (GRCm38)	missense	probably benign	0.24
R8452:Fsip2	UTSW	2	82,984,593 (GRCm38)	missense	probably benign
R8459:Fsip2	UTSW	2	82,979,678 (GRCm38)	missense	possibly damaging	0.95
R8465:Fsip2	UTSW	2	82,979,940 (GRCm38)	missense	probably benign	0.26
R8473:Fsip2	UTSW	2	82,946,992 (GRCm38)	missense	probably damaging	0.99
R8703:Fsip2	UTSW	2	82,991,527 (GRCm38)	missense	probably damaging	0.98
R8711:Fsip2	UTSW	2	82,984,902 (GRCm38)	missense	possibly damaging	0.53
R8713:Fsip2	UTSW	2	82,981,109 (GRCm38)	missense	probably damaging	1.00
R8789:Fsip2	UTSW	2	82,985,478 (GRCm38)	missense	possibly damaging	0.73
R8805:Fsip2	UTSW	2	82,983,109 (GRCm38)	missense	possibly damaging	0.46
R8840:Fsip2	UTSW	2	82,991,262 (GRCm38)	missense	probably benign	0.03
R8855:Fsip2	UTSW	2	82,980,177 (GRCm38)	missense	probably benign	0.04
R8866:Fsip2	UTSW	2	82,980,177 (GRCm38)	missense	probably benign	0.04
R8875:Fsip2	UTSW	2	82,990,438 (GRCm38)	missense	possibly damaging	0.95
R8883:Fsip2	UTSW	2	82,979,180 (GRCm38)	missense	possibly damaging	0.68
R8903:Fsip2	UTSW	2	82,977,337 (GRCm38)	missense	possibly damaging	0.83
R8907:Fsip2	UTSW	2	82,986,640 (GRCm38)	missense	probably benign	0.20
R8912:Fsip2	UTSW	2	82,980,594 (GRCm38)	missense	probably benign
R8926:Fsip2	UTSW	2	82,993,583 (GRCm38)	missense	possibly damaging	0.84
R8991:Fsip2	UTSW	2	82,985,026 (GRCm38)	missense	probably benign	0.33
R9014:Fsip2	UTSW	2	82,976,554 (GRCm38)	missense	probably benign	0.32
R9014:Fsip2	UTSW	2	82,986,731 (GRCm38)	missense	possibly damaging	0.71
R9039:Fsip2	UTSW	2	82,998,201 (GRCm38)	missense	probably benign	0.32
R9054:Fsip2	UTSW	2	82,975,836 (GRCm38)	missense	possibly damaging	0.68
R9114:Fsip2	UTSW	2	82,976,957 (GRCm38)	missense	probably benign	0.00
R9124:Fsip2	UTSW	2	82,985,759 (GRCm38)	missense	probably benign	0.00
R9131:Fsip2	UTSW	2	82,982,826 (GRCm38)	missense	probably benign
R9149:Fsip2	UTSW	2	82,982,030 (GRCm38)	missense	possibly damaging	0.86
R9180:Fsip2	UTSW	2	82,985,230 (GRCm38)	missense	possibly damaging	0.96
R9192:Fsip2	UTSW	2	82,987,500 (GRCm38)	missense	probably benign	0.06
R9216:Fsip2	UTSW	2	82,990,081 (GRCm38)	missense	probably damaging	0.99
R9218:Fsip2	UTSW	2	82,992,718 (GRCm38)	missense	probably damaging	0.97
R9222:Fsip2	UTSW	2	82,985,614 (GRCm38)	missense	probably benign	0.00
R9262:Fsip2	UTSW	2	82,977,318 (GRCm38)	missense	probably benign	0.00
R9340:Fsip2	UTSW	2	82,988,260 (GRCm38)	missense	possibly damaging	0.71
R9342:Fsip2	UTSW	2	82,988,403 (GRCm38)	missense	possibly damaging	0.71
R9368:Fsip2	UTSW	2	82,980,695 (GRCm38)	missense	possibly damaging	0.68
R9372:Fsip2	UTSW	2	82,992,412 (GRCm38)	missense	possibly damaging	0.71
R9385:Fsip2	UTSW	2	82,989,449 (GRCm38)	missense	possibly damaging	0.84
R9432:Fsip2	UTSW	2	82,975,563 (GRCm38)	missense	probably damaging	0.98
R9434:Fsip2	UTSW	2	82,986,358 (GRCm38)	missense	possibly damaging	0.71
R9445:Fsip2	UTSW	2	82,975,788 (GRCm38)	missense	probably damaging	0.99
R9472:Fsip2	UTSW	2	82,986,941 (GRCm38)	missense	possibly damaging	0.85
R9496:Fsip2	UTSW	2	82,962,718 (GRCm38)	missense	probably benign
R9523:Fsip2	UTSW	2	82,977,628 (GRCm38)	missense	probably damaging	0.99
R9567:Fsip2	UTSW	2	82,967,829 (GRCm38)	missense	probably benign
R9636:Fsip2	UTSW	2	82,990,219 (GRCm38)	missense	possibly damaging	0.52
R9643:Fsip2	UTSW	2	82,991,640 (GRCm38)	missense	possibly damaging	0.53
R9680:Fsip2	UTSW	2	82,988,928 (GRCm38)	missense	probably benign	0.32
R9695:Fsip2	UTSW	2	82,975,882 (GRCm38)	missense	probably benign
R9705:Fsip2	UTSW	2	82,993,290 (GRCm38)	missense	probably benign
R9739:Fsip2	UTSW	2	82,993,552 (GRCm38)	missense	possibly damaging	0.71
R9751:Fsip2	UTSW	2	82,987,897 (GRCm38)	missense	probably benign	0.00
R9761:Fsip2	UTSW	2	82,991,650 (GRCm38)	missense	probably benign	0.00
R9798:Fsip2	UTSW	2	82,979,881 (GRCm38)	nonsense	probably null
RF003:Fsip2	UTSW	2	82,991,521 (GRCm38)	missense	probably benign	0.02
RF005:Fsip2	UTSW	2	82,992,532 (GRCm38)	missense	probably benign	0.04
RF008:Fsip2	UTSW	2	82,977,840 (GRCm38)	missense	probably benign
RF028:Fsip2	UTSW	2	82,994,008 (GRCm38)	frame shift	probably null
RF029:Fsip2	UTSW	2	82,994,008 (GRCm38)	frame shift	probably null
RF036:Fsip2	UTSW	2	82,984,363 (GRCm38)	critical splice acceptor site	probably benign
RF038:Fsip2	UTSW	2	82,994,008 (GRCm38)	frame shift	probably null
RF062:Fsip2	UTSW	2	82,984,363 (GRCm38)	critical splice acceptor site	probably benign
X0018:Fsip2	UTSW	2	82,982,507 (GRCm38)	nonsense	probably null
X0020:Fsip2	UTSW	2	82,951,020 (GRCm38)	missense	probably damaging	1.00
X0025:Fsip2	UTSW	2	82,954,946 (GRCm38)	missense	possibly damaging	0.70
X0027:Fsip2	UTSW	2	82,976,778 (GRCm38)	missense	probably benign	0.35
X0066:Fsip2	UTSW	2	82,987,463 (GRCm38)	missense	possibly damaging	0.51
Z1088:Fsip2	UTSW	2	82,988,634 (GRCm38)	missense	possibly damaging	0.85
Z1088:Fsip2	UTSW	2	82,987,653 (GRCm38)	missense	possibly damaging	0.86
Z1088:Fsip2	UTSW	2	82,975,448 (GRCm38)	missense	probably damaging	0.96
Z1176:Fsip2	UTSW	2	82,989,665 (GRCm38)	missense	probably benign	0.02
Z1177:Fsip2	UTSW	2	82,984,524 (GRCm38)	missense	probably damaging	0.98
Z1177:Fsip2	UTSW	2	82,946,960 (GRCm38)	missense	probably damaging	0.99
Z1177:Fsip2	UTSW	2	82,987,203 (GRCm38)	missense	possibly damaging	0.71

Predicted Primers

PCR Primer
(F):5'- CGTAGCAAATCTTCCTTTACGC -3'
(R):5'- AAACAGGTATGCTACTTAGGCCC -3'

Sequencing Primer
(F):5'- ATGTCTTGGTGAACAAAGTGC -3'
(R):5'- GGCCCTTTTTATCTTTTGTAAGAGAC -3'

Posted On

2020-01-23