Incidental Mutation 'R8021:Fer1l4'
| ID |
617343 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Fer1l4
|
| Ensembl Gene |
ENSMUSG00000013338 |
| Gene Name |
fer-1 like family member 4 |
| Synonyms |
9130402C12Rik |
| MMRRC Submission |
067460-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R8021 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
2 |
| Chromosomal Location |
155861059-155894867 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 155864511 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Phenylalanine
at position 1668
(I1668F)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000105240
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000006035]
[ENSMUST00000088650]
[ENSMUST00000109611]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000006035
|
| SMART Domains |
Protein: ENSMUSP00000006035
Gene: ENSMUSG00000005881
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:ERGIC_N
|
6 |
101 |
2.2e-38 |
PFAM |
|
Pfam:COPIIcoated_ERV
|
145 |
363 |
6.2e-86 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000088650
|
| SMART Domains |
Protein: ENSMUSP00000086025
Gene: ENSMUSG00000005881
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:ERGIC_N
|
7 |
97 |
9e-35 |
PFAM |
|
Pfam:COPIIcoated_ERV
|
145 |
374 |
7e-94 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000109611
AA Change: I1668F
PolyPhen 2
Score 0.983 (Sensitivity: 0.75; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000105240
Gene: ENSMUSG00000013338
AA Change: I1668F
| Domain | Start | End | E-Value | Type |
|---|
|
PDB:3L9B|A
|
1 |
122 |
1e-12 |
PDB |
|
Blast:C2
|
2 |
96 |
2e-51 |
BLAST |
|
low complexity region
|
159 |
172 |
N/A |
INTRINSIC |
|
low complexity region
|
178 |
197 |
N/A |
INTRINSIC |
|
C2
|
228 |
329 |
2.87e-7 |
SMART |
|
FerI
|
312 |
383 |
7.93e-29 |
SMART |
|
C2
|
391 |
501 |
3.64e-9 |
SMART |
|
low complexity region
|
574 |
581 |
N/A |
INTRINSIC |
|
low complexity region
|
611 |
622 |
N/A |
INTRINSIC |
|
low complexity region
|
829 |
837 |
N/A |
INTRINSIC |
|
low complexity region
|
844 |
855 |
N/A |
INTRINSIC |
|
FerB
|
861 |
932 |
7.27e-37 |
SMART |
|
C2
|
968 |
1076 |
3.73e-6 |
SMART |
|
low complexity region
|
1249 |
1257 |
N/A |
INTRINSIC |
|
low complexity region
|
1280 |
1310 |
N/A |
INTRINSIC |
|
low complexity region
|
1327 |
1340 |
N/A |
INTRINSIC |
|
low complexity region
|
1397 |
1407 |
N/A |
INTRINSIC |
|
C2
|
1449 |
1548 |
5.65e-15 |
SMART |
|
C2
|
1692 |
1822 |
4.22e-5 |
SMART |
|
Pfam:Ferlin_C
|
1834 |
1987 |
1.6e-74 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000142859
|
| SMART Domains |
Protein: ENSMUSP00000115912
Gene: ENSMUSG00000005881
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:COPIIcoated_ERV
|
74 |
246 |
1.9e-67 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000155370
|
| SMART Domains |
Protein: ENSMUSP00000119051
Gene: ENSMUSG00000005881
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:COPIIcoated_ERV
|
21 |
235 |
1e-95 |
PFAM |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.3%
|
| Validation Efficiency |
97% (74/76) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 77 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1810010H24Rik |
A |
G |
11: 106,916,753 (GRCm39) |
I12V |
unknown |
Het |
| A630010A05Rik |
C |
T |
16: 14,407,110 (GRCm39) |
T13I |
|
Het |
| Acsm5 |
A |
G |
7: 119,141,616 (GRCm39) |
E537G |
possibly damaging |
Het |
| Adam25 |
C |
A |
8: 41,207,796 (GRCm39) |
A354E |
probably damaging |
Het |
| Adamts3 |
T |
C |
5: 89,831,043 (GRCm39) |
K1004E |
possibly damaging |
Het |
| Ap3d1 |
C |
A |
10: 80,550,135 (GRCm39) |
V699L |
probably benign |
Het |
| Arel1 |
T |
G |
12: 84,981,732 (GRCm39) |
H216P |
possibly damaging |
Het |
| Armc12 |
T |
A |
17: 28,749,879 (GRCm39) |
F8I |
probably benign |
Het |
| Armh3 |
C |
T |
19: 45,945,180 (GRCm39) |
|
probably null |
Het |
| Ascc3 |
T |
A |
10: 50,607,744 (GRCm39) |
M1416K |
probably benign |
Het |
| Catsperb |
A |
C |
12: 101,554,322 (GRCm39) |
N672T |
probably benign |
Het |
| Ccdc30 |
T |
C |
4: 119,209,876 (GRCm39) |
H291R |
probably benign |
Het |
| Cd33 |
A |
G |
7: 43,178,262 (GRCm39) |
V371A |
unknown |
Het |
| Cpt1b |
A |
T |
15: 89,305,629 (GRCm39) |
M362K |
probably benign |
Het |
| Dusp5 |
T |
A |
19: 53,517,929 (GRCm39) |
S61T |
probably benign |
Het |
| Eogt |
T |
G |
6: 97,111,291 (GRCm39) |
D190A |
probably damaging |
Het |
| Fat3 |
T |
A |
9: 15,910,405 (GRCm39) |
I1866F |
probably damaging |
Het |
| Foxn3 |
A |
T |
12: 99,355,161 (GRCm39) |
M1K |
probably null |
Het |
| Frs3 |
T |
A |
17: 48,014,039 (GRCm39) |
V244E |
probably damaging |
Het |
| Grik1 |
C |
T |
16: 87,711,110 (GRCm39) |
V832I |
|
Het |
| Gtf2ird2 |
T |
A |
5: 134,232,175 (GRCm39) |
V242E |
probably benign |
Het |
| Gtpbp2 |
C |
T |
17: 46,475,195 (GRCm39) |
R97C |
possibly damaging |
Het |
| Habp2 |
T |
A |
19: 56,302,485 (GRCm39) |
V263E |
probably benign |
Het |
| Iars2 |
T |
A |
1: 185,054,654 (GRCm39) |
I337L |
probably benign |
Het |
| Ifi204 |
T |
C |
1: 173,586,919 (GRCm39) |
|
probably benign |
Het |
| Itih2 |
T |
C |
2: 10,110,463 (GRCm39) |
T543A |
probably benign |
Het |
| Kdm2b |
A |
G |
5: 123,070,982 (GRCm39) |
S372P |
probably damaging |
Het |
| Kit |
T |
A |
5: 75,776,151 (GRCm39) |
V311E |
possibly damaging |
Het |
| Kmt2c |
C |
G |
5: 25,492,117 (GRCm39) |
V4230L |
possibly damaging |
Het |
| Lao1 |
T |
C |
4: 118,825,674 (GRCm39) |
I498T |
probably damaging |
Het |
| Lrp1 |
G |
T |
10: 127,384,215 (GRCm39) |
D3641E |
possibly damaging |
Het |
| Mapk8ip1 |
A |
T |
2: 92,216,760 (GRCm39) |
S477T |
possibly damaging |
Het |
| Mast3 |
C |
T |
8: 71,240,896 (GRCm39) |
G218S |
probably benign |
Het |
| Mical1 |
T |
C |
10: 41,358,720 (GRCm39) |
V546A |
probably damaging |
Het |
| Nck2 |
T |
C |
1: 43,593,420 (GRCm39) |
V209A |
probably benign |
Het |
| Ndufs4 |
A |
G |
13: 114,444,351 (GRCm39) |
|
probably null |
Het |
| Nek3 |
C |
T |
8: 22,647,206 (GRCm39) |
V139M |
probably damaging |
Het |
| Or10v5 |
T |
C |
19: 11,806,256 (GRCm39) |
I45V |
probably benign |
Het |
| Or5ak24 |
A |
T |
2: 85,260,996 (GRCm39) |
M59K |
probably damaging |
Het |
| Or7e171-ps1 |
A |
C |
9: 19,853,375 (GRCm39) |
Y120* |
probably null |
Het |
| Or8b9 |
T |
A |
9: 37,766,592 (GRCm39) |
H159Q |
probably damaging |
Het |
| Otog |
A |
T |
7: 45,916,766 (GRCm39) |
N901I |
probably damaging |
Het |
| Pclo |
A |
C |
5: 14,589,798 (GRCm39) |
Q699H |
unknown |
Het |
| Pcnx1 |
C |
T |
12: 81,965,593 (GRCm39) |
R59* |
probably null |
Het |
| Pde12 |
A |
T |
14: 26,386,854 (GRCm39) |
Y551* |
probably null |
Het |
| Pigg |
A |
G |
5: 108,467,805 (GRCm39) |
D268G |
probably damaging |
Het |
| Ppp1r21 |
A |
G |
17: 88,856,935 (GRCm39) |
D130G |
probably benign |
Het |
| Psip1 |
T |
C |
4: 83,378,192 (GRCm39) |
T435A |
possibly damaging |
Het |
| Rad54l2 |
T |
C |
9: 106,596,840 (GRCm39) |
S189G |
probably benign |
Het |
| Rgs14 |
T |
C |
13: 55,531,569 (GRCm39) |
C498R |
probably damaging |
Het |
| Ripply3 |
C |
A |
16: 94,129,369 (GRCm39) |
A5E |
probably benign |
Het |
| Rps6ka4 |
T |
C |
19: 6,807,777 (GRCm39) |
D676G |
probably benign |
Het |
| Rsbn1 |
T |
C |
3: 103,835,898 (GRCm39) |
L312S |
possibly damaging |
Het |
| Secisbp2 |
T |
A |
13: 51,819,664 (GRCm39) |
*415R |
probably null |
Het |
| Sephs1 |
T |
A |
2: 4,911,434 (GRCm39) |
F336Y |
probably benign |
Het |
| Setdb2 |
A |
T |
14: 59,660,833 (GRCm39) |
Y103* |
probably null |
Het |
| Slit2 |
T |
A |
5: 48,459,834 (GRCm39) |
C1371* |
probably null |
Het |
| Spata31e4 |
A |
G |
13: 50,855,130 (GRCm39) |
N256S |
possibly damaging |
Het |
| Stab2 |
C |
T |
10: 86,741,403 (GRCm39) |
A1239T |
possibly damaging |
Het |
| Taf4b |
T |
A |
18: 14,937,581 (GRCm39) |
V218E |
probably damaging |
Het |
| Tars2 |
T |
C |
3: 95,654,826 (GRCm39) |
N393S |
probably benign |
Het |
| Tbc1d30 |
A |
G |
10: 121,103,448 (GRCm39) |
M528T |
probably benign |
Het |
| Tchp |
A |
G |
5: 114,856,478 (GRCm39) |
E363G |
probably damaging |
Het |
| Tec |
T |
A |
5: 72,914,812 (GRCm39) |
N568I |
probably benign |
Het |
| Ticam1 |
A |
G |
17: 56,577,089 (GRCm39) |
S669P |
unknown |
Het |
| Tnk1 |
A |
G |
11: 69,745,810 (GRCm39) |
S372P |
probably benign |
Het |
| Tnpo2 |
G |
A |
8: 85,781,835 (GRCm39) |
A847T |
probably damaging |
Het |
| Tsc1 |
A |
T |
2: 28,576,901 (GRCm39) |
I1068F |
possibly damaging |
Het |
| Ttc14 |
T |
A |
3: 33,863,270 (GRCm39) |
Y559* |
probably null |
Het |
| Ttc41 |
C |
A |
10: 86,569,578 (GRCm39) |
T652N |
probably benign |
Het |
| Tut1 |
T |
A |
19: 8,932,873 (GRCm39) |
S69T |
probably benign |
Het |
| Uck1 |
T |
C |
2: 32,149,929 (GRCm39) |
S40G |
probably benign |
Het |
| Vmn2r76 |
G |
A |
7: 85,874,958 (GRCm39) |
T673I |
probably damaging |
Het |
| Vps13d |
G |
T |
4: 144,875,245 (GRCm39) |
P1760H |
|
Het |
| Zbp1 |
T |
C |
2: 173,051,003 (GRCm39) |
N289S |
possibly damaging |
Het |
| Zc3hav1l |
C |
A |
6: 38,274,882 (GRCm39) |
|
probably benign |
Het |
| Zzef1 |
A |
T |
11: 72,714,242 (GRCm39) |
D244V |
probably damaging |
Het |
|
| Other mutations in Fer1l4 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00417:Fer1l4
|
APN |
2 |
155,861,840 (GRCm39) |
nonsense |
probably null |
|
|
IGL01025:Fer1l4
|
APN |
2 |
155,894,105 (GRCm39) |
missense |
probably benign |
0.41 |
|
IGL01103:Fer1l4
|
APN |
2 |
155,886,361 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01322:Fer1l4
|
APN |
2 |
155,862,259 (GRCm39) |
splice site |
probably null |
|
|
IGL01391:Fer1l4
|
APN |
2 |
155,878,376 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02176:Fer1l4
|
APN |
2 |
155,890,371 (GRCm39) |
missense |
probably benign |
|
|
IGL02267:Fer1l4
|
APN |
2 |
155,873,172 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
IGL02291:Fer1l4
|
APN |
2 |
155,861,458 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02385:Fer1l4
|
APN |
2 |
155,887,348 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL02423:Fer1l4
|
APN |
2 |
155,894,827 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL02596:Fer1l4
|
APN |
2 |
155,881,052 (GRCm39) |
missense |
probably benign |
|
|
IGL02612:Fer1l4
|
APN |
2 |
155,889,848 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02716:Fer1l4
|
APN |
2 |
155,871,635 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02738:Fer1l4
|
APN |
2 |
155,887,648 (GRCm39) |
missense |
probably benign |
|
|
IGL03035:Fer1l4
|
APN |
2 |
155,864,526 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL03083:Fer1l4
|
APN |
2 |
155,881,286 (GRCm39) |
unclassified |
probably benign |
|
|
IGL03201:Fer1l4
|
APN |
2 |
155,886,650 (GRCm39) |
missense |
probably benign |
0.32 |
|
IGL03349:Fer1l4
|
APN |
2 |
155,886,654 (GRCm39) |
nonsense |
probably null |
|
|
R0033:Fer1l4
|
UTSW |
2 |
155,866,026 (GRCm39) |
splice site |
probably benign |
|
|
R0356:Fer1l4
|
UTSW |
2 |
155,865,930 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0477:Fer1l4
|
UTSW |
2 |
155,894,806 (GRCm39) |
missense |
probably benign |
0.43 |
|
R0504:Fer1l4
|
UTSW |
2 |
155,894,115 (GRCm39) |
missense |
probably benign |
0.36 |
|
R0731:Fer1l4
|
UTSW |
2 |
155,865,990 (GRCm39) |
missense |
probably benign |
0.17 |
|
R0800:Fer1l4
|
UTSW |
2 |
155,887,583 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0884:Fer1l4
|
UTSW |
2 |
155,861,233 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1017:Fer1l4
|
UTSW |
2 |
155,891,398 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R1266:Fer1l4
|
UTSW |
2 |
155,888,169 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1544:Fer1l4
|
UTSW |
2 |
155,887,553 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1657:Fer1l4
|
UTSW |
2 |
155,877,518 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1699:Fer1l4
|
UTSW |
2 |
155,871,605 (GRCm39) |
missense |
probably benign |
0.14 |
|
R1816:Fer1l4
|
UTSW |
2 |
155,877,119 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1950:Fer1l4
|
UTSW |
2 |
155,890,194 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2117:Fer1l4
|
UTSW |
2 |
155,881,038 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2219:Fer1l4
|
UTSW |
2 |
155,873,684 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2220:Fer1l4
|
UTSW |
2 |
155,873,684 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2879:Fer1l4
|
UTSW |
2 |
155,894,120 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3746:Fer1l4
|
UTSW |
2 |
155,876,968 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3806:Fer1l4
|
UTSW |
2 |
155,887,603 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3807:Fer1l4
|
UTSW |
2 |
155,887,603 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4224:Fer1l4
|
UTSW |
2 |
155,862,309 (GRCm39) |
missense |
probably benign |
0.37 |
|
R4274:Fer1l4
|
UTSW |
2 |
155,862,464 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4569:Fer1l4
|
UTSW |
2 |
155,878,559 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R4619:Fer1l4
|
UTSW |
2 |
155,889,007 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4707:Fer1l4
|
UTSW |
2 |
155,887,543 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R4914:Fer1l4
|
UTSW |
2 |
155,873,220 (GRCm39) |
missense |
probably benign |
0.41 |
|
R4915:Fer1l4
|
UTSW |
2 |
155,873,220 (GRCm39) |
missense |
probably benign |
0.41 |
|
R4917:Fer1l4
|
UTSW |
2 |
155,873,220 (GRCm39) |
missense |
probably benign |
0.41 |
|
R4918:Fer1l4
|
UTSW |
2 |
155,873,220 (GRCm39) |
missense |
probably benign |
0.41 |
|
R4941:Fer1l4
|
UTSW |
2 |
155,887,009 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5011:Fer1l4
|
UTSW |
2 |
155,873,135 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5013:Fer1l4
|
UTSW |
2 |
155,873,135 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5130:Fer1l4
|
UTSW |
2 |
155,891,386 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R5385:Fer1l4
|
UTSW |
2 |
155,879,286 (GRCm39) |
nonsense |
probably null |
|
|
R5441:Fer1l4
|
UTSW |
2 |
155,865,177 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5555:Fer1l4
|
UTSW |
2 |
155,890,109 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5838:Fer1l4
|
UTSW |
2 |
155,893,913 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6125:Fer1l4
|
UTSW |
2 |
155,888,907 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6184:Fer1l4
|
UTSW |
2 |
155,890,211 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6246:Fer1l4
|
UTSW |
2 |
155,866,902 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6248:Fer1l4
|
UTSW |
2 |
155,888,091 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6274:Fer1l4
|
UTSW |
2 |
155,871,188 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6298:Fer1l4
|
UTSW |
2 |
155,866,660 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6362:Fer1l4
|
UTSW |
2 |
155,890,170 (GRCm39) |
missense |
probably benign |
0.08 |
|
R6490:Fer1l4
|
UTSW |
2 |
155,889,834 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6494:Fer1l4
|
UTSW |
2 |
155,887,390 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6516:Fer1l4
|
UTSW |
2 |
155,877,119 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6530:Fer1l4
|
UTSW |
2 |
155,889,785 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6740:Fer1l4
|
UTSW |
2 |
155,873,142 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7039:Fer1l4
|
UTSW |
2 |
155,878,650 (GRCm39) |
missense |
probably benign |
0.05 |
|
R7121:Fer1l4
|
UTSW |
2 |
155,886,477 (GRCm39) |
missense |
probably benign |
0.13 |
|
R7132:Fer1l4
|
UTSW |
2 |
155,887,546 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7382:Fer1l4
|
UTSW |
2 |
155,862,669 (GRCm39) |
nonsense |
probably null |
|
|
R7631:Fer1l4
|
UTSW |
2 |
155,890,195 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7693:Fer1l4
|
UTSW |
2 |
155,862,351 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R7730:Fer1l4
|
UTSW |
2 |
155,890,854 (GRCm39) |
missense |
probably benign |
|
|
R8161:Fer1l4
|
UTSW |
2 |
155,866,555 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8171:Fer1l4
|
UTSW |
2 |
155,890,151 (GRCm39) |
missense |
probably benign |
0.29 |
|
R8241:Fer1l4
|
UTSW |
2 |
155,891,585 (GRCm39) |
missense |
probably benign |
|
|
R8245:Fer1l4
|
UTSW |
2 |
155,886,934 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8280:Fer1l4
|
UTSW |
2 |
155,891,620 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8369:Fer1l4
|
UTSW |
2 |
155,861,680 (GRCm39) |
missense |
probably benign |
0.17 |
|
R8403:Fer1l4
|
UTSW |
2 |
155,894,163 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R8702:Fer1l4
|
UTSW |
2 |
155,861,310 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8804:Fer1l4
|
UTSW |
2 |
155,893,914 (GRCm39) |
missense |
probably benign |
0.28 |
|
R8814:Fer1l4
|
UTSW |
2 |
155,894,163 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8817:Fer1l4
|
UTSW |
2 |
155,890,143 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9325:Fer1l4
|
UTSW |
2 |
155,877,934 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9342:Fer1l4
|
UTSW |
2 |
155,877,196 (GRCm39) |
missense |
probably benign |
0.08 |
|
R9527:Fer1l4
|
UTSW |
2 |
155,871,617 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9661:Fer1l4
|
UTSW |
2 |
155,862,336 (GRCm39) |
missense |
probably damaging |
0.98 |
|
RF030:Fer1l4
|
UTSW |
2 |
155,887,449 (GRCm39) |
small deletion |
probably benign |
|
|
X0063:Fer1l4
|
UTSW |
2 |
155,876,931 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Fer1l4
|
UTSW |
2 |
155,890,349 (GRCm39) |
missense |
probably null |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TATACACAACAATGCTCGTGGC -3'
(R):5'- TTGCCTTGACCTTGGGAAC -3'
Sequencing Primer
(F):5'- CACAACAATGCTCGTGGCTTATGG -3'
(R):5'- GGAACCTCACGTTAGACTCG -3'
|
| Posted On |
2020-01-23 |
Incidental Mutation