Mutagenetix > Incidental Mutation

Incidental Mutation 'R8022:Nbeal1'

617411

Institutional Source

Beutler Lab

Gene Symbol

Nbeal1

Ensembl Gene

ENSMUSG00000073664

Gene Name

neurobeachin like 1

Synonyms

A530083I02Rik, A530050O19Rik, ALS2CR17, 2310076G13Rik

MMRRC Submission

067461-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R8022 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

60180599-60338328 bp(+) (GRCm38)

Type of Mutation

nonsense

DNA Base Change (assembly)

C to T at 60260272 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Glutamine to Stop codon at position 1256 (Q1256*)

Ref Sequence

ENSEMBL: ENSMUSP00000124056 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000160834] [ENSMUST00000162291]

AlphaFold

E9PYP2

Predicted Effect

probably benign
Transcript: ENSMUST00000035569

SMART Domains

Protein: ENSMUSP00000049393
Gene: ENSMUSG00000073664

Domain	Start	End	E-Value	Type
low complexity region	522	541	N/A	INTRINSIC
low complexity region	719	735	N/A	INTRINSIC
Pfam:DUF4704	851	1130	3.4e-39	PFAM
low complexity region	1383	1401	N/A	INTRINSIC
Pfam:DUF4800	1575	1828	6.3e-126	PFAM
coiled coil region	1859	1882	N/A	INTRINSIC
Pfam:PH_BEACH	1889	1975	2e-24	PFAM
Beach	1998	2278	7.2e-199	SMART
Blast:Beach	2342	2405	6e-30	BLAST
WD40	2425	2463	5.52e-2	SMART
WD40	2475	2514	4.95e-4	SMART
WD40	2604	2649	7.64e1	SMART

Predicted Effect

probably null
Transcript: ENSMUST00000160834
AA Change: Q1256*

SMART Domains

Protein: ENSMUSP00000124056
Gene: ENSMUSG00000073664
AA Change: Q1256*

Domain	Start	End	E-Value	Type
low complexity region	522	541	N/A	INTRINSIC
Pfam:Laminin_G_3	567	801	8.3e-9	PFAM
low complexity region	1383	1401	N/A	INTRINSIC
low complexity region	1849	1865	N/A	INTRINSIC
Pfam:PH_BEACH	1882	1975	4.9e-32	PFAM
Beach	1998	2278	7.2e-199	SMART
Blast:Beach	2342	2405	6e-30	BLAST
WD40	2425	2463	5.52e-2	SMART
WD40	2475	2514	4.95e-4	SMART
WD40	2604	2649	7.64e1	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000162291

SMART Domains

Protein: ENSMUSP00000125592
Gene: ENSMUSG00000073664

Domain	Start	End	E-Value	Type
low complexity region	114	132	N/A	INTRINSIC
low complexity region	580	596	N/A	INTRINSIC
Pfam:PH_BEACH	613	706	9.6e-33	PFAM

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.6%
20x: 98.6%

Validation Efficiency

Allele List at MGI

All alleles(16) : Targeted(1) Gene trapped(15)

Other mutations in this stock

Total: 87 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Acacb	A	T	5: 114,223,854 (GRCm38)	T1386S	probably benign	Het
AI661453	T	G	17: 47,466,236 (GRCm38)	S296A	unknown	Het
Ambp	G	T	4: 63,144,197 (GRCm38)	N268K	probably damaging	Het
Ankrd11	T	C	8: 122,887,593 (GRCm38)	K2503E	probably damaging	Het
Ap1g1	C	A	8: 109,832,735 (GRCm38)	R221S	possibly damaging	Het
Ap5z1	T	C	5: 142,470,149 (GRCm38)		probably null	Het
Aspa	A	C	11: 73,322,206 (GRCm38)	N103K	probably benign	Het
BC049730	T	A	7: 24,714,174 (GRCm38)	I205N	possibly damaging	Het
Bend7	G	A	2: 4,752,779 (GRCm38)	V211I	probably benign	Het
Bsn	A	G	9: 108,114,404 (GRCm38)	M1383T	probably benign	Het
Cad	G	T	5: 31,068,806 (GRCm38)	V1117F	probably damaging	Het
Cdh2	A	G	18: 16,590,301 (GRCm38)	L856S	probably damaging	Het
Cdh7	T	A	1: 110,061,108 (GRCm38)	S247T	probably benign	Het
Ces1b	A	G	8: 93,069,315 (GRCm38)		probably null	Het
Chd7	T	A	4: 8,751,605 (GRCm38)	V34E	unknown	Het
Clca3a2	A	T	3: 144,805,766 (GRCm38)	F623I	probably damaging	Het
Cope	T	G	8: 70,312,803 (GRCm38)	M217R	probably benign	Het
Crim1	T	A	17: 78,315,555 (GRCm38)	I394N	possibly damaging	Het
Crnkl1	A	T	2: 145,918,566 (GRCm38)	I644N	probably damaging	Het
Cry1	G	A	10: 85,146,402 (GRCm38)	A360V	probably damaging	Het
Ctcfl	A	T	2: 173,118,766 (GRCm38)	V8D	probably benign	Het
Cyp2d34	G	A	15: 82,616,114 (GRCm38)	Q475*	probably null	Het
Cyp39a1	T	C	17: 43,746,577 (GRCm38)	Y436H	probably damaging	Het
Cyp3a25	T	A	5: 145,977,668 (GRCm38)	Q484L	probably benign	Het
Dnah1	A	G	14: 31,265,014 (GRCm38)	F3607S	probably damaging	Het
Dnali1	T	A	4: 125,065,530 (GRCm38)	K23N	possibly damaging	Het
Ecel1	T	C	1: 87,153,330 (GRCm38)	I313V	probably benign	Het
Ehhadh	C	A	16: 21,777,820 (GRCm38)	A53S	probably benign	Het
Epcam	T	C	17: 87,646,308 (GRCm38)	S277P	probably benign	Het
Fbxo10	T	C	4: 45,062,062 (GRCm38)	I155V	possibly damaging	Het
Fgd6	A	T	10: 94,044,344 (GRCm38)	K353N	possibly damaging	Het
Glce	A	T	9: 62,060,591 (GRCm38)	M426K	probably benign	Het
Glmp	A	T	3: 88,326,520 (GRCm38)	N228I	probably damaging	Het
Gm4787	C	A	12: 81,377,720 (GRCm38)	V555F	possibly damaging	Het
Gm5114	T	A	7: 39,409,376 (GRCm38)	H273L	probably benign	Het
Gzmg	T	A	14: 56,157,446 (GRCm38)	T122S	probably benign	Het
Hace1	T	C	10: 45,700,970 (GRCm38)	V820A	probably damaging	Het
Igf2r	T	A	17: 12,718,795 (GRCm38)	D535V	probably damaging	Het
Kcnd3	A	G	3: 105,458,873 (GRCm38)	M20V	probably benign	Het
Kcnn3	T	G	3: 89,609,703 (GRCm38)	I473S	possibly damaging	Het
Klhl35	T	A	7: 99,473,239 (GRCm38)	F94Y	unknown	Het
Kmt2c	C	T	5: 25,281,680 (GRCm38)	V4712I	possibly damaging	Het
Lepr	A	G	4: 101,782,557 (GRCm38)	E740G	probably benign	Het
Lmod3	T	C	6: 97,248,299 (GRCm38)	D187G	probably benign	Het
Lsm3	C	T	6: 91,519,561 (GRCm38)	H49Y	probably benign	Het
Magi1	T	C	6: 93,697,365 (GRCm38)	S962G	probably damaging	Het
Man2b1	G	A	8: 85,095,613 (GRCm38)	R782Q	probably damaging	Het
Mical2	A	T	7: 112,303,767 (GRCm38)	K148N	probably damaging	Het
Ncam1	G	T	9: 49,564,892 (GRCm38)	A299D	possibly damaging	Het
Ncapg	A	G	5: 45,681,794 (GRCm38)	D512G	probably damaging	Het
Nkiras2	A	G	11: 100,624,287 (GRCm38)	N28D	probably benign	Het
Nprl2	A	C	9: 107,543,061 (GRCm38)	K53T	probably damaging	Het
Nr4a3	T	A	4: 48,051,510 (GRCm38)	I88N	probably damaging	Het
Oas3	A	G	5: 120,756,966 (GRCm38)	I986T	possibly damaging	Het
Olfr809	A	T	10: 129,776,785 (GRCm38)	L305F	possibly damaging	Het
Pcsk1	A	T	13: 75,099,293 (GRCm38)	Y187F	possibly damaging	Het
Pgc	A	G	17: 47,728,776 (GRCm38)	T32A	probably benign	Het
Ranbp2	A	C	10: 58,485,861 (GRCm38)	D2660A	possibly damaging	Het
Retreg1	A	G	15: 25,843,479 (GRCm38)	R46G		Het
Rrbp1	C	A	2: 143,956,792 (GRCm38)	K1100N	probably benign	Het
Rsph10b	A	T	5: 143,967,232 (GRCm38)	T676S	probably benign	Het
Setdb1	A	T	3: 95,338,599 (GRCm38)	F672I	probably damaging	Het
Setdb1	T	A	3: 95,347,085 (GRCm38)	D195V	probably damaging	Het
Slc12a8	A	G	16: 33,625,086 (GRCm38)	E450G	probably benign	Het
Slc1a7	G	A	4: 108,012,276 (GRCm38)	V513M	probably benign	Het
Slc25a12	A	T	2: 71,275,189 (GRCm38)	V667E	unknown	Het
Slc39a3	T	C	10: 81,031,277 (GRCm38)	T212A	probably benign	Het
Slc45a1	C	T	4: 150,638,309 (GRCm38)	G373S	possibly damaging	Het
Snx11	G	A	11: 96,772,854 (GRCm38)	T53M	probably damaging	Het
Snx33	A	G	9: 56,925,340 (GRCm38)	F482L	possibly damaging	Het
Srebf2	C	T	15: 82,178,765 (GRCm38)	R468C	probably damaging	Het
Stk32a	C	T	18: 43,315,101 (GRCm38)	Q382*	probably null	Het
Sun3	C	A	11: 9,023,376 (GRCm38)	S167I	probably damaging	Het
Sycp2	A	G	2: 178,355,062 (GRCm38)	L1116P	probably damaging	Het
Thbs4	T	G	13: 92,752,447 (GRCm38)	T913P	probably damaging	Het
Trav8d-1	C	T	14: 52,778,827 (GRCm38)	Q57*	probably null	Het
Trio	C	G	15: 27,749,866 (GRCm38)	V2250L	probably benign	Het
Unc119b	A	T	5: 115,127,043 (GRCm38)	I204N	probably damaging	Het
Usp4	A	G	9: 108,378,471 (GRCm38)	E576G	probably damaging	Het
Uvssa	T	A	5: 33,409,504 (GRCm38)	L515Q	probably damaging	Het
Xkr8	T	C	4: 132,732,338 (GRCm38)	Y43C	probably damaging	Het
Xpo6	G	A	7: 126,169,254 (GRCm38)	L94F	probably benign	Het
Zbtb11	A	G	16: 56,006,020 (GRCm38)	K804R	probably damaging	Het
Zfp616	A	G	11: 74,084,068 (GRCm38)	R479G	probably benign	Het
Zfp661	T	C	2: 127,577,924 (GRCm38)	T99A	probably benign	Het
Zfp839	A	T	12: 110,855,098 (GRCm38)	Q115H	probably damaging	Het
Zyg11a	C	T	4: 108,189,568 (GRCm38)		probably null	Het

Other mutations in Nbeal1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00094:Nbeal1	APN	1	60,235,191 (GRCm38)	nonsense	probably null	0.00
IGL00334:Nbeal1	APN	1	60,281,883 (GRCm38)	missense	probably damaging	0.98
IGL00334:Nbeal1	APN	1	60,328,103 (GRCm38)	missense	probably damaging	1.00
IGL00514:Nbeal1	APN	1	60,217,225 (GRCm38)	missense	probably benign	0.31
IGL00596:Nbeal1	APN	1	60,181,741 (GRCm38)	missense	probably damaging	0.96
IGL00654:Nbeal1	APN	1	60,195,011 (GRCm38)	critical splice acceptor site	probably benign	0.00
IGL00757:Nbeal1	APN	1	60,195,143 (GRCm38)	missense	possibly damaging	0.82
IGL00771:Nbeal1	APN	1	60,235,353 (GRCm38)	missense	probably benign	0.11
IGL01315:Nbeal1	APN	1	60,281,341 (GRCm38)	missense	probably damaging	1.00
IGL01445:Nbeal1	APN	1	60,242,625 (GRCm38)	critical splice donor site	probably null
IGL01456:Nbeal1	APN	1	60,230,628 (GRCm38)	missense	probably damaging	1.00
IGL01458:Nbeal1	APN	1	60,242,625 (GRCm38)	critical splice donor site	probably null
IGL01535:Nbeal1	APN	1	60,217,255 (GRCm38)	missense	probably damaging	1.00
IGL01608:Nbeal1	APN	1	60,242,535 (GRCm38)	critical splice acceptor site	probably benign	0.00
IGL02006:Nbeal1	APN	1	60,272,259 (GRCm38)	critical splice donor site	probably null
IGL02105:Nbeal1	APN	1	60,253,501 (GRCm38)	missense	probably damaging	1.00
IGL02409:Nbeal1	APN	1	60,329,335 (GRCm38)	missense	probably benign	0.01
IGL02713:Nbeal1	APN	1	60,235,237 (GRCm38)	missense	possibly damaging	0.94
IGL02720:Nbeal1	APN	1	60,283,987 (GRCm38)	missense	probably damaging	0.98
IGL02887:Nbeal1	APN	1	60,287,444 (GRCm38)	splice site	probably benign
IGL02945:Nbeal1	APN	1	60,206,410 (GRCm38)	missense	probably damaging	1.00
IGL03023:Nbeal1	APN	1	60,253,413 (GRCm38)	missense	probably damaging	0.98
IGL03114:Nbeal1	APN	1	60,278,727 (GRCm38)	missense	probably damaging	1.00
IGL03231:Nbeal1	APN	1	60,236,459 (GRCm38)	missense	probably benign	0.44
IGL03241:Nbeal1	APN	1	60,234,868 (GRCm38)	missense	possibly damaging	0.46
IGL03241:Nbeal1	APN	1	60,234,869 (GRCm38)	missense	probably benign	0.44
IGL03382:Nbeal1	APN	1	60,261,586 (GRCm38)	critical splice donor site	probably null
IGL03412:Nbeal1	APN	1	60,242,567 (GRCm38)	nonsense	probably null
coach	UTSW	1	60,253,481 (GRCm38)	nonsense	probably null
Committee	UTSW	1	60,292,903 (GRCm38)	missense	probably damaging	1.00
Disgrace	UTSW	1	60,281,310 (GRCm38)	nonsense	probably null
Dravrah	UTSW	1	60,284,092 (GRCm38)	missense	probably damaging	1.00
Harvard	UTSW	1	60,235,563 (GRCm38)	splice site	probably null
horrified	UTSW	1	60,244,824 (GRCm38)	missense	probably damaging	1.00
Lampoon	UTSW	1	60,261,586 (GRCm38)	critical splice donor site	probably null
lawyer	UTSW	1	60,310,224 (GRCm38)	nonsense	probably null
magistrate	UTSW	1	60,194,597 (GRCm38)	critical splice donor site	probably null
Maratimus	UTSW	1	60,291,888 (GRCm38)	missense	probably damaging	1.00
National	UTSW	1	60,222,263 (GRCm38)	missense	possibly damaging	0.95
phainopepla	UTSW	1	60,319,687 (GRCm38)	missense	probably damaging	1.00
R3875_Nbeal1_770	UTSW	1	60,194,599 (GRCm38)	splice site	probably benign
satirical	UTSW	1	60,235,562 (GRCm38)	critical splice donor site	probably null
silky	UTSW	1	60,330,878 (GRCm38)	splice site	probably benign
stiggs	UTSW	1	60,237,151 (GRCm38)	missense	probably benign	0.11
3-1:Nbeal1	UTSW	1	60,264,272 (GRCm38)	splice site	probably benign
P0007:Nbeal1	UTSW	1	60,319,688 (GRCm38)	missense	probably damaging	0.98
P0028:Nbeal1	UTSW	1	60,291,937 (GRCm38)	missense	probably damaging	1.00
R0041:Nbeal1	UTSW	1	60,281,871 (GRCm38)	missense	probably benign	0.05
R0051:Nbeal1	UTSW	1	60,310,263 (GRCm38)	missense	probably benign	0.19
R0052:Nbeal1	UTSW	1	60,228,612 (GRCm38)	splice site	probably benign
R0054:Nbeal1	UTSW	1	60,287,401 (GRCm38)	utr 3 prime	probably benign
R0062:Nbeal1	UTSW	1	60,247,717 (GRCm38)	missense	probably benign	0.01
R0062:Nbeal1	UTSW	1	60,247,717 (GRCm38)	missense	probably benign	0.01
R0094:Nbeal1	UTSW	1	60,305,309 (GRCm38)	missense	possibly damaging	0.62
R0310:Nbeal1	UTSW	1	60,305,370 (GRCm38)	splice site	probably benign
R0324:Nbeal1	UTSW	1	60,292,873 (GRCm38)	missense	probably damaging	1.00
R0329:Nbeal1	UTSW	1	60,268,063 (GRCm38)	missense	probably damaging	1.00
R0330:Nbeal1	UTSW	1	60,268,063 (GRCm38)	missense	probably damaging	1.00
R0417:Nbeal1	UTSW	1	60,247,734 (GRCm38)	missense	probably benign	0.00
R0421:Nbeal1	UTSW	1	60,268,439 (GRCm38)	missense	probably benign	0.08
R0617:Nbeal1	UTSW	1	60,281,832 (GRCm38)	nonsense	probably null
R1034:Nbeal1	UTSW	1	60,290,006 (GRCm38)	nonsense	probably null
R1082:Nbeal1	UTSW	1	60,312,226 (GRCm38)	missense	probably damaging	0.99
R1123:Nbeal1	UTSW	1	60,260,269 (GRCm38)	missense	probably benign
R1187:Nbeal1	UTSW	1	60,194,528 (GRCm38)	missense	probably damaging	1.00
R1484:Nbeal1	UTSW	1	60,200,939 (GRCm38)	missense	probably damaging	1.00
R1594:Nbeal1	UTSW	1	60,305,291 (GRCm38)	missense	possibly damaging	0.91
R1651:Nbeal1	UTSW	1	60,200,119 (GRCm38)	missense	probably damaging	1.00
R1678:Nbeal1	UTSW	1	60,260,334 (GRCm38)	missense	probably benign	0.00
R1806:Nbeal1	UTSW	1	60,284,092 (GRCm38)	missense	probably damaging	1.00
R1937:Nbeal1	UTSW	1	60,267,941 (GRCm38)	nonsense	probably null
R1952:Nbeal1	UTSW	1	60,234,840 (GRCm38)	missense	probably damaging	1.00
R1953:Nbeal1	UTSW	1	60,234,840 (GRCm38)	missense	probably damaging	1.00
R2038:Nbeal1	UTSW	1	60,206,344 (GRCm38)	missense	probably benign	0.00
R2044:Nbeal1	UTSW	1	60,319,687 (GRCm38)	missense	probably damaging	1.00
R2050:Nbeal1	UTSW	1	60,292,964 (GRCm38)	splice site	probably null
R2055:Nbeal1	UTSW	1	60,311,057 (GRCm38)	missense	probably damaging	1.00
R2064:Nbeal1	UTSW	1	60,270,356 (GRCm38)	missense	possibly damaging	0.89
R2100:Nbeal1	UTSW	1	60,305,271 (GRCm38)	splice site	probably null
R2181:Nbeal1	UTSW	1	60,278,780 (GRCm38)	missense	probably damaging	1.00
R2192:Nbeal1	UTSW	1	60,281,895 (GRCm38)	missense	probably damaging	1.00
R2203:Nbeal1	UTSW	1	60,284,006 (GRCm38)	missense	probably benign	0.21
R2267:Nbeal1	UTSW	1	60,330,878 (GRCm38)	splice site	probably benign
R2268:Nbeal1	UTSW	1	60,330,878 (GRCm38)	splice site	probably benign
R2351:Nbeal1	UTSW	1	60,237,098 (GRCm38)	missense	possibly damaging	0.90
R2366:Nbeal1	UTSW	1	60,251,352 (GRCm38)	missense	probably damaging	0.97
R2393:Nbeal1	UTSW	1	60,251,370 (GRCm38)	missense	probably damaging	0.98
R3545:Nbeal1	UTSW	1	60,278,780 (GRCm38)	missense	probably damaging	1.00
R3546:Nbeal1	UTSW	1	60,278,780 (GRCm38)	missense	probably damaging	1.00
R3547:Nbeal1	UTSW	1	60,278,780 (GRCm38)	missense	probably damaging	1.00
R3701:Nbeal1	UTSW	1	60,251,413 (GRCm38)	splice site	probably benign
R3747:Nbeal1	UTSW	1	60,195,023 (GRCm38)	missense	probably damaging	0.98
R3875:Nbeal1	UTSW	1	60,194,599 (GRCm38)	splice site	probably benign
R4119:Nbeal1	UTSW	1	60,291,870 (GRCm38)	missense	probably damaging	0.99
R4256:Nbeal1	UTSW	1	60,330,948 (GRCm38)	missense	probably benign	0.19
R4371:Nbeal1	UTSW	1	60,289,946 (GRCm38)	missense	possibly damaging	0.95
R4450:Nbeal1	UTSW	1	60,267,774 (GRCm38)	missense	probably damaging	0.97
R4558:Nbeal1	UTSW	1	60,281,310 (GRCm38)	nonsense	probably null
R4618:Nbeal1	UTSW	1	60,228,731 (GRCm38)	intron	probably benign
R4673:Nbeal1	UTSW	1	60,329,390 (GRCm38)	missense	probably damaging	1.00
R4719:Nbeal1	UTSW	1	60,235,563 (GRCm38)	splice site	probably null
R4798:Nbeal1	UTSW	1	60,222,193 (GRCm38)	splice site	probably null
R4826:Nbeal1	UTSW	1	60,251,342 (GRCm38)	missense	possibly damaging	0.79
R4841:Nbeal1	UTSW	1	60,253,375 (GRCm38)	missense	probably damaging	1.00
R4842:Nbeal1	UTSW	1	60,253,375 (GRCm38)	missense	probably damaging	1.00
R4895:Nbeal1	UTSW	1	60,292,903 (GRCm38)	missense	probably damaging	1.00
R4929:Nbeal1	UTSW	1	60,238,654 (GRCm38)	missense	probably damaging	1.00
R5026:Nbeal1	UTSW	1	60,237,179 (GRCm38)	missense	probably damaging	1.00
R5243:Nbeal1	UTSW	1	60,270,328 (GRCm38)	missense	probably damaging	0.99
R5300:Nbeal1	UTSW	1	60,235,559 (GRCm38)	nonsense	probably null
R5345:Nbeal1	UTSW	1	60,328,210 (GRCm38)	critical splice donor site	probably null
R5502:Nbeal1	UTSW	1	60,310,999 (GRCm38)	missense	probably damaging	1.00
R5542:Nbeal1	UTSW	1	60,277,194 (GRCm38)	missense	probably benign	0.00
R5555:Nbeal1	UTSW	1	60,237,152 (GRCm38)	missense	possibly damaging	0.93
R5580:Nbeal1	UTSW	1	60,242,602 (GRCm38)	missense	probably benign	0.45
R5765:Nbeal1	UTSW	1	60,291,847 (GRCm38)	missense	probably damaging	1.00
R5802:Nbeal1	UTSW	1	60,272,221 (GRCm38)	missense	probably benign	0.01
R5907:Nbeal1	UTSW	1	60,228,791 (GRCm38)	intron	probably benign
R5918:Nbeal1	UTSW	1	60,267,892 (GRCm38)	missense	possibly damaging	0.90
R5923:Nbeal1	UTSW	1	60,248,395 (GRCm38)	missense	probably damaging	1.00
R6066:Nbeal1	UTSW	1	60,248,405 (GRCm38)	missense	probably benign	0.29
R6091:Nbeal1	UTSW	1	60,181,556 (GRCm38)	start gained	probably benign
R6113:Nbeal1	UTSW	1	60,222,263 (GRCm38)	missense	possibly damaging	0.95
R6143:Nbeal1	UTSW	1	60,251,307 (GRCm38)	missense	possibly damaging	0.81
R6194:Nbeal1	UTSW	1	60,257,484 (GRCm38)	missense	possibly damaging	0.80
R6197:Nbeal1	UTSW	1	60,222,128 (GRCm38)	missense	probably damaging	0.99
R6228:Nbeal1	UTSW	1	60,295,924 (GRCm38)	missense	probably benign	0.00
R6229:Nbeal1	UTSW	1	60,248,365 (GRCm38)	missense	possibly damaging	0.88
R6309:Nbeal1	UTSW	1	60,238,719 (GRCm38)	missense	probably benign
R6457:Nbeal1	UTSW	1	60,253,474 (GRCm38)	missense	probably benign	0.31
R6489:Nbeal1	UTSW	1	60,330,942 (GRCm38)	missense	possibly damaging	0.89
R6845:Nbeal1	UTSW	1	60,281,310 (GRCm38)	nonsense	probably null
R7021:Nbeal1	UTSW	1	60,261,586 (GRCm38)	critical splice donor site	probably null
R7033:Nbeal1	UTSW	1	60,310,947 (GRCm38)	missense	probably damaging	1.00
R7144:Nbeal1	UTSW	1	60,237,151 (GRCm38)	missense	probably benign	0.11
R7145:Nbeal1	UTSW	1	60,237,151 (GRCm38)	missense	probably benign	0.11
R7146:Nbeal1	UTSW	1	60,237,151 (GRCm38)	missense	probably benign	0.11
R7157:Nbeal1	UTSW	1	60,260,634 (GRCm38)	nonsense	probably null
R7157:Nbeal1	UTSW	1	60,237,158 (GRCm38)	missense	probably damaging	1.00
R7209:Nbeal1	UTSW	1	60,237,151 (GRCm38)	missense	probably benign	0.11
R7210:Nbeal1	UTSW	1	60,237,151 (GRCm38)	missense	probably benign	0.11
R7211:Nbeal1	UTSW	1	60,200,951 (GRCm38)	missense	probably damaging	1.00
R7212:Nbeal1	UTSW	1	60,237,151 (GRCm38)	missense	probably benign	0.11
R7213:Nbeal1	UTSW	1	60,237,151 (GRCm38)	missense	probably benign	0.11
R7214:Nbeal1	UTSW	1	60,237,151 (GRCm38)	missense	probably benign	0.11
R7283:Nbeal1	UTSW	1	60,237,151 (GRCm38)	missense	probably benign	0.11
R7285:Nbeal1	UTSW	1	60,237,151 (GRCm38)	missense	probably benign	0.11
R7287:Nbeal1	UTSW	1	60,237,151 (GRCm38)	missense	probably benign	0.11
R7296:Nbeal1	UTSW	1	60,310,224 (GRCm38)	nonsense	probably null
R7312:Nbeal1	UTSW	1	60,237,151 (GRCm38)	missense	probably benign	0.11
R7313:Nbeal1	UTSW	1	60,237,151 (GRCm38)	missense	probably benign	0.11
R7329:Nbeal1	UTSW	1	60,217,196 (GRCm38)	missense	probably benign	0.39
R7380:Nbeal1	UTSW	1	60,244,810 (GRCm38)	missense	probably damaging	1.00
R7414:Nbeal1	UTSW	1	60,194,597 (GRCm38)	critical splice donor site	probably null
R7477:Nbeal1	UTSW	1	60,261,584 (GRCm38)	missense	probably benign
R7507:Nbeal1	UTSW	1	60,235,467 (GRCm38)	missense	probably damaging	1.00
R7642:Nbeal1	UTSW	1	60,277,227 (GRCm38)	missense	probably benign	0.31
R7678:Nbeal1	UTSW	1	60,237,151 (GRCm38)	missense	probably benign	0.11
R7689:Nbeal1	UTSW	1	60,237,151 (GRCm38)	missense	probably benign	0.11
R7728:Nbeal1	UTSW	1	60,244,824 (GRCm38)	missense	probably damaging	1.00
R7757:Nbeal1	UTSW	1	60,257,450 (GRCm38)	missense	probably damaging	0.97
R7761:Nbeal1	UTSW	1	60,319,341 (GRCm38)	missense	probably benign	0.00
R7813:Nbeal1	UTSW	1	60,291,889 (GRCm38)	missense	probably damaging	1.00
R7829:Nbeal1	UTSW	1	60,237,151 (GRCm38)	missense	probably benign	0.11
R7891:Nbeal1	UTSW	1	60,260,432 (GRCm38)	missense	probably benign
R7902:Nbeal1	UTSW	1	60,291,870 (GRCm38)	missense	probably damaging	0.99
R8053:Nbeal1	UTSW	1	60,279,795 (GRCm38)	missense	probably damaging	0.98
R8169:Nbeal1	UTSW	1	60,237,151 (GRCm38)	missense	probably benign	0.11
R8170:Nbeal1	UTSW	1	60,237,151 (GRCm38)	missense	probably benign	0.11
R8178:Nbeal1	UTSW	1	60,237,151 (GRCm38)	missense	probably benign	0.11
R8182:Nbeal1	UTSW	1	60,200,133 (GRCm38)	missense	probably benign	0.00
R8186:Nbeal1	UTSW	1	60,237,151 (GRCm38)	missense	probably benign	0.11
R8187:Nbeal1	UTSW	1	60,237,151 (GRCm38)	missense	probably benign	0.11
R8193:Nbeal1	UTSW	1	60,253,481 (GRCm38)	nonsense	probably null
R8209:Nbeal1	UTSW	1	60,277,177 (GRCm38)	missense	probably damaging	0.99
R8226:Nbeal1	UTSW	1	60,277,177 (GRCm38)	missense	probably damaging	0.99
R8549:Nbeal1	UTSW	1	60,235,562 (GRCm38)	critical splice donor site	probably null
R8560:Nbeal1	UTSW	1	60,235,157 (GRCm38)	missense	probably benign	0.38
R8753:Nbeal1	UTSW	1	60,268,383 (GRCm38)	missense	probably damaging	1.00
R8769:Nbeal1	UTSW	1	60,235,211 (GRCm38)	missense	probably damaging	0.99
R8771:Nbeal1	UTSW	1	60,261,584 (GRCm38)	missense	probably benign
R8952:Nbeal1	UTSW	1	60,260,300 (GRCm38)	missense	probably benign	0.01
R9014:Nbeal1	UTSW	1	60,289,959 (GRCm38)	missense	probably damaging	1.00
R9056:Nbeal1	UTSW	1	60,278,726 (GRCm38)	missense	probably damaging	1.00
R9091:Nbeal1	UTSW	1	60,268,389 (GRCm38)	missense	possibly damaging	0.50
R9138:Nbeal1	UTSW	1	60,247,745 (GRCm38)	nonsense	probably null
R9168:Nbeal1	UTSW	1	60,291,888 (GRCm38)	missense	probably damaging	1.00
R9200:Nbeal1	UTSW	1	60,281,266 (GRCm38)	missense	probably damaging	1.00
R9205:Nbeal1	UTSW	1	60,278,680 (GRCm38)	missense	probably damaging	1.00
R9270:Nbeal1	UTSW	1	60,268,389 (GRCm38)	missense	possibly damaging	0.50
R9322:Nbeal1	UTSW	1	60,258,659 (GRCm38)	missense	possibly damaging	0.91
R9405:Nbeal1	UTSW	1	60,310,265 (GRCm38)	missense	probably damaging	1.00
R9554:Nbeal1	UTSW	1	60,251,128 (GRCm38)	nonsense	probably null
R9557:Nbeal1	UTSW	1	60,235,350 (GRCm38)	missense	probably benign
R9560:Nbeal1	UTSW	1	60,329,385 (GRCm38)	missense	probably damaging	1.00
R9641:Nbeal1	UTSW	1	60,311,088 (GRCm38)	missense	probably damaging	1.00
R9784:Nbeal1	UTSW	1	60,260,582 (GRCm38)	nonsense	probably null
X0022:Nbeal1	UTSW	1	60,277,232 (GRCm38)	missense	probably benign

Predicted Primers

PCR Primer
(F):5'- AAGGTAGCTGAGGGTCTCTG -3'
(R):5'- TCTGAAGATACGTCAGCTAACATC -3'

Sequencing Primer
(F):5'- TAGCTCCAGGTTCCATGAGAGAC -3'
(R):5'- TGAAACTGTCTTCCCGTG -3'

Posted On

2020-01-23