Mutagenetix > Incidental Mutation

Incidental Mutation 'R8022:Ankrd11'

617459

Institutional Source

Beutler Lab

Gene Symbol

Ankrd11

Ensembl Gene

ENSMUSG00000035569

Gene Name

ankyrin repeat domain 11

Synonyms

3010027A04Rik, Yod, 2410104C19Rik, 9530048I21Rik

MMRRC Submission

067461-MU

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

R8022 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

122883822-123042277 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 122887593 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Lysine to Glutamic Acid at position 2503 (K2503E)

Ref Sequence

ENSEMBL: ENSMUSP00000095938 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000098333] [ENSMUST00000098334] [ENSMUST00000127664] [ENSMUST00000172906]

AlphaFold

E9Q4F7

Predicted Effect

probably damaging
Transcript: ENSMUST00000098333
AA Change: K2503E

PolyPhen 2 Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000095938
Gene: ENSMUSG00000035569
AA Change: K2503E

Domain	Start	End	E-Value	Type
ANK	188	217	2.58e-3	SMART
ANK	221	250	1.31e-4	SMART
ANK	254	283	5.04e-6	SMART
low complexity region	311	324	N/A	INTRINSIC
low complexity region	366	377	N/A	INTRINSIC
low complexity region	429	440	N/A	INTRINSIC
low complexity region	470	487	N/A	INTRINSIC
low complexity region	499	521	N/A	INTRINSIC
low complexity region	534	549	N/A	INTRINSIC
low complexity region	596	609	N/A	INTRINSIC
low complexity region	649	669	N/A	INTRINSIC
coiled coil region	786	826	N/A	INTRINSIC
low complexity region	867	877	N/A	INTRINSIC
low complexity region	965	984	N/A	INTRINSIC
low complexity region	1040	1055	N/A	INTRINSIC
low complexity region	1058	1082	N/A	INTRINSIC
low complexity region	1187	1200	N/A	INTRINSIC
low complexity region	1204	1227	N/A	INTRINSIC
low complexity region	1268	1289	N/A	INTRINSIC
low complexity region	1294	1306	N/A	INTRINSIC
coiled coil region	1374	1406	N/A	INTRINSIC
low complexity region	1476	1496	N/A	INTRINSIC
low complexity region	1508	1523	N/A	INTRINSIC
low complexity region	1526	1547	N/A	INTRINSIC
coiled coil region	1598	1625	N/A	INTRINSIC
low complexity region	1770	1781	N/A	INTRINSIC
low complexity region	1874	1885	N/A	INTRINSIC
low complexity region	1913	1922	N/A	INTRINSIC
low complexity region	1969	1979	N/A	INTRINSIC
low complexity region	2035	2045	N/A	INTRINSIC
low complexity region	2057	2071	N/A	INTRINSIC
low complexity region	2162	2179	N/A	INTRINSIC
low complexity region	2191	2209	N/A	INTRINSIC
low complexity region	2224	2236	N/A	INTRINSIC
low complexity region	2250	2263	N/A	INTRINSIC
low complexity region	2294	2305	N/A	INTRINSIC
low complexity region	2391	2409	N/A	INTRINSIC
low complexity region	2445	2455	N/A	INTRINSIC

Predicted Effect

probably damaging
Transcript: ENSMUST00000098334
AA Change: K2482E

PolyPhen 2 Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000095939
Gene: ENSMUSG00000035569
AA Change: K2482E

Domain	Start	End	E-Value	Type
ANK	167	196	2.58e-3	SMART
ANK	200	229	1.31e-4	SMART
ANK	233	262	5.04e-6	SMART
low complexity region	290	303	N/A	INTRINSIC
low complexity region	345	356	N/A	INTRINSIC
low complexity region	408	419	N/A	INTRINSIC
low complexity region	449	466	N/A	INTRINSIC
low complexity region	478	500	N/A	INTRINSIC
low complexity region	513	528	N/A	INTRINSIC
low complexity region	575	588	N/A	INTRINSIC
low complexity region	628	648	N/A	INTRINSIC
coiled coil region	765	805	N/A	INTRINSIC
low complexity region	846	856	N/A	INTRINSIC
low complexity region	944	963	N/A	INTRINSIC
low complexity region	1019	1034	N/A	INTRINSIC
low complexity region	1037	1061	N/A	INTRINSIC
low complexity region	1166	1179	N/A	INTRINSIC
low complexity region	1183	1206	N/A	INTRINSIC
low complexity region	1247	1268	N/A	INTRINSIC
low complexity region	1273	1285	N/A	INTRINSIC
coiled coil region	1353	1385	N/A	INTRINSIC
low complexity region	1455	1475	N/A	INTRINSIC
low complexity region	1487	1502	N/A	INTRINSIC
low complexity region	1505	1526	N/A	INTRINSIC
coiled coil region	1577	1604	N/A	INTRINSIC
low complexity region	1749	1760	N/A	INTRINSIC
low complexity region	1853	1864	N/A	INTRINSIC
low complexity region	1892	1901	N/A	INTRINSIC
low complexity region	1948	1958	N/A	INTRINSIC
low complexity region	2014	2024	N/A	INTRINSIC
low complexity region	2036	2050	N/A	INTRINSIC
low complexity region	2141	2158	N/A	INTRINSIC
low complexity region	2170	2188	N/A	INTRINSIC
low complexity region	2203	2215	N/A	INTRINSIC
low complexity region	2229	2242	N/A	INTRINSIC
low complexity region	2273	2284	N/A	INTRINSIC
low complexity region	2370	2388	N/A	INTRINSIC
low complexity region	2424	2434	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000127664

SMART Domains

Protein: ENSMUSP00000118564
Gene: ENSMUSG00000092329

Domain	Start	End	E-Value	Type
Pfam:Glycos_transf_2	104	287	7.4e-31	PFAM
Pfam:Glyco_transf_7C	261	331	4.9e-8	PFAM
RICIN	406	531	9.28e-27	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000172906

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.6%
20x: 98.6%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This locus encodes an ankryin repeat domain-containing protein. The encoded protein inhibits ligand-dependent activation of transcription. Mutations in this gene have been associated with KBG syndrome, which is characterized by macrodontia, distinctive craniofacial features, short stature, skeletal anomalies, global developmental delay, seizures and intellectual disability. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 2 and X. [provided by RefSeq, Jan 2012]
PHENOTYPE: Mice homozygous for a spontaneous allele die by E9.5, are small and fail to turn. Mice heterozygous for a spontaneous allele exhibit craniofacial abnormalities, decreased weight, osteoporosis and osteopenia. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 87 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Acacb	A	T	5: 114,223,854 (GRCm38)	T1386S	probably benign	Het
AI661453	T	G	17: 47,466,236 (GRCm38)	S296A	unknown	Het
Ambp	G	T	4: 63,144,197 (GRCm38)	N268K	probably damaging	Het
Ap1g1	C	A	8: 109,832,735 (GRCm38)	R221S	possibly damaging	Het
Ap5z1	T	C	5: 142,470,149 (GRCm38)		probably null	Het
Aspa	A	C	11: 73,322,206 (GRCm38)	N103K	probably benign	Het
BC049730	T	A	7: 24,714,174 (GRCm38)	I205N	possibly damaging	Het
Bend7	G	A	2: 4,752,779 (GRCm38)	V211I	probably benign	Het
Bsn	A	G	9: 108,114,404 (GRCm38)	M1383T	probably benign	Het
Cad	G	T	5: 31,068,806 (GRCm38)	V1117F	probably damaging	Het
Cdh2	A	G	18: 16,590,301 (GRCm38)	L856S	probably damaging	Het
Cdh7	T	A	1: 110,061,108 (GRCm38)	S247T	probably benign	Het
Ces1b	A	G	8: 93,069,315 (GRCm38)		probably null	Het
Chd7	T	A	4: 8,751,605 (GRCm38)	V34E	unknown	Het
Clca3a2	A	T	3: 144,805,766 (GRCm38)	F623I	probably damaging	Het
Cope	T	G	8: 70,312,803 (GRCm38)	M217R	probably benign	Het
Crim1	T	A	17: 78,315,555 (GRCm38)	I394N	possibly damaging	Het
Crnkl1	A	T	2: 145,918,566 (GRCm38)	I644N	probably damaging	Het
Cry1	G	A	10: 85,146,402 (GRCm38)	A360V	probably damaging	Het
Ctcfl	A	T	2: 173,118,766 (GRCm38)	V8D	probably benign	Het
Cyp2d34	G	A	15: 82,616,114 (GRCm38)	Q475*	probably null	Het
Cyp39a1	T	C	17: 43,746,577 (GRCm38)	Y436H	probably damaging	Het
Cyp3a25	T	A	5: 145,977,668 (GRCm38)	Q484L	probably benign	Het
Dnah1	A	G	14: 31,265,014 (GRCm38)	F3607S	probably damaging	Het
Dnali1	T	A	4: 125,065,530 (GRCm38)	K23N	possibly damaging	Het
Ecel1	T	C	1: 87,153,330 (GRCm38)	I313V	probably benign	Het
Ehhadh	C	A	16: 21,777,820 (GRCm38)	A53S	probably benign	Het
Epcam	T	C	17: 87,646,308 (GRCm38)	S277P	probably benign	Het
Fbxo10	T	C	4: 45,062,062 (GRCm38)	I155V	possibly damaging	Het
Fgd6	A	T	10: 94,044,344 (GRCm38)	K353N	possibly damaging	Het
Glce	A	T	9: 62,060,591 (GRCm38)	M426K	probably benign	Het
Glmp	A	T	3: 88,326,520 (GRCm38)	N228I	probably damaging	Het
Gm4787	C	A	12: 81,377,720 (GRCm38)	V555F	possibly damaging	Het
Gm5114	T	A	7: 39,409,376 (GRCm38)	H273L	probably benign	Het
Gzmg	T	A	14: 56,157,446 (GRCm38)	T122S	probably benign	Het
Hace1	T	C	10: 45,700,970 (GRCm38)	V820A	probably damaging	Het
Igf2r	T	A	17: 12,718,795 (GRCm38)	D535V	probably damaging	Het
Kcnd3	A	G	3: 105,458,873 (GRCm38)	M20V	probably benign	Het
Kcnn3	T	G	3: 89,609,703 (GRCm38)	I473S	possibly damaging	Het
Klhl35	T	A	7: 99,473,239 (GRCm38)	F94Y	unknown	Het
Kmt2c	C	T	5: 25,281,680 (GRCm38)	V4712I	possibly damaging	Het
Lepr	A	G	4: 101,782,557 (GRCm38)	E740G	probably benign	Het
Lmod3	T	C	6: 97,248,299 (GRCm38)	D187G	probably benign	Het
Lsm3	C	T	6: 91,519,561 (GRCm38)	H49Y	probably benign	Het
Magi1	T	C	6: 93,697,365 (GRCm38)	S962G	probably damaging	Het
Man2b1	G	A	8: 85,095,613 (GRCm38)	R782Q	probably damaging	Het
Mical2	A	T	7: 112,303,767 (GRCm38)	K148N	probably damaging	Het
Nbeal1	C	T	1: 60,260,272 (GRCm38)	Q1256*	probably null	Het
Ncam1	G	T	9: 49,564,892 (GRCm38)	A299D	possibly damaging	Het
Ncapg	A	G	5: 45,681,794 (GRCm38)	D512G	probably damaging	Het
Nkiras2	A	G	11: 100,624,287 (GRCm38)	N28D	probably benign	Het
Nprl2	A	C	9: 107,543,061 (GRCm38)	K53T	probably damaging	Het
Nr4a3	T	A	4: 48,051,510 (GRCm38)	I88N	probably damaging	Het
Oas3	A	G	5: 120,756,966 (GRCm38)	I986T	possibly damaging	Het
Olfr809	A	T	10: 129,776,785 (GRCm38)	L305F	possibly damaging	Het
Pcsk1	A	T	13: 75,099,293 (GRCm38)	Y187F	possibly damaging	Het
Pgc	A	G	17: 47,728,776 (GRCm38)	T32A	probably benign	Het
Ranbp2	A	C	10: 58,485,861 (GRCm38)	D2660A	possibly damaging	Het
Retreg1	A	G	15: 25,843,479 (GRCm38)	R46G		Het
Rrbp1	C	A	2: 143,956,792 (GRCm38)	K1100N	probably benign	Het
Rsph10b	A	T	5: 143,967,232 (GRCm38)	T676S	probably benign	Het
Setdb1	T	A	3: 95,347,085 (GRCm38)	D195V	probably damaging	Het
Setdb1	A	T	3: 95,338,599 (GRCm38)	F672I	probably damaging	Het
Slc12a8	A	G	16: 33,625,086 (GRCm38)	E450G	probably benign	Het
Slc1a7	G	A	4: 108,012,276 (GRCm38)	V513M	probably benign	Het
Slc25a12	A	T	2: 71,275,189 (GRCm38)	V667E	unknown	Het
Slc39a3	T	C	10: 81,031,277 (GRCm38)	T212A	probably benign	Het
Slc45a1	C	T	4: 150,638,309 (GRCm38)	G373S	possibly damaging	Het
Snx11	G	A	11: 96,772,854 (GRCm38)	T53M	probably damaging	Het
Snx33	A	G	9: 56,925,340 (GRCm38)	F482L	possibly damaging	Het
Srebf2	C	T	15: 82,178,765 (GRCm38)	R468C	probably damaging	Het
Stk32a	C	T	18: 43,315,101 (GRCm38)	Q382*	probably null	Het
Sun3	C	A	11: 9,023,376 (GRCm38)	S167I	probably damaging	Het
Sycp2	A	G	2: 178,355,062 (GRCm38)	L1116P	probably damaging	Het
Thbs4	T	G	13: 92,752,447 (GRCm38)	T913P	probably damaging	Het
Trav8d-1	C	T	14: 52,778,827 (GRCm38)	Q57*	probably null	Het
Trio	C	G	15: 27,749,866 (GRCm38)	V2250L	probably benign	Het
Unc119b	A	T	5: 115,127,043 (GRCm38)	I204N	probably damaging	Het
Usp4	A	G	9: 108,378,471 (GRCm38)	E576G	probably damaging	Het
Uvssa	T	A	5: 33,409,504 (GRCm38)	L515Q	probably damaging	Het
Xkr8	T	C	4: 132,732,338 (GRCm38)	Y43C	probably damaging	Het
Xpo6	G	A	7: 126,169,254 (GRCm38)	L94F	probably benign	Het
Zbtb11	A	G	16: 56,006,020 (GRCm38)	K804R	probably damaging	Het
Zfp616	A	G	11: 74,084,068 (GRCm38)	R479G	probably benign	Het
Zfp661	T	C	2: 127,577,924 (GRCm38)	T99A	probably benign	Het
Zfp839	A	T	12: 110,855,098 (GRCm38)	Q115H	probably damaging	Het
Zyg11a	C	T	4: 108,189,568 (GRCm38)		probably null	Het

Other mutations in Ankrd11

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00949:Ankrd11	APN	8	122,908,728 (GRCm38)	missense	possibly damaging	0.59
IGL00971:Ankrd11	APN	8	122,895,353 (GRCm38)	missense	probably damaging	1.00
IGL01017:Ankrd11	APN	8	122,894,728 (GRCm38)	missense	probably damaging	1.00
IGL01137:Ankrd11	APN	8	122,884,336 (GRCm38)	missense	probably damaging	0.99
IGL01659:Ankrd11	APN	8	122,895,371 (GRCm38)	missense	probably damaging	1.00
IGL01920:Ankrd11	APN	8	122,915,897 (GRCm38)	splice site	probably benign
IGL01964:Ankrd11	APN	8	122,889,736 (GRCm38)	missense	probably damaging	0.97
IGL02131:Ankrd11	APN	8	122,894,410 (GRCm38)	missense	probably damaging	1.00
IGL02226:Ankrd11	APN	8	122,892,245 (GRCm38)	missense	probably damaging	1.00
IGL02549:Ankrd11	APN	8	122,891,293 (GRCm38)	missense	probably damaging	1.00
IGL02642:Ankrd11	APN	8	122,890,651 (GRCm38)	missense	probably damaging	1.00
IGL02643:Ankrd11	APN	8	122,892,322 (GRCm38)	missense	probably damaging	0.98
IGL02861:Ankrd11	APN	8	122,895,827 (GRCm38)	missense	probably damaging	0.99
IGL03086:Ankrd11	APN	8	122,894,510 (GRCm38)	missense	probably damaging	1.00
IGL03336:Ankrd11	APN	8	122,891,843 (GRCm38)	missense	probably benign	0.00
anchors	UTSW	8	122,895,770 (GRCm38)	missense	probably damaging	0.99
away	UTSW	8	122,891,953 (GRCm38)	missense	probably damaging	1.00
bluebell	UTSW	8	122,891,785 (GRCm38)	missense	probably damaging	0.97
Navy	UTSW	8	122,908,734 (GRCm38)	nonsense	probably null
BB001:Ankrd11	UTSW	8	122,895,902 (GRCm38)	missense	possibly damaging	0.95
BB011:Ankrd11	UTSW	8	122,895,902 (GRCm38)	missense	possibly damaging	0.95
R0051:Ankrd11	UTSW	8	122,889,742 (GRCm38)	missense	probably damaging	1.00
R0051:Ankrd11	UTSW	8	122,889,742 (GRCm38)	missense	probably damaging	1.00
R0110:Ankrd11	UTSW	8	122,892,175 (GRCm38)	missense	possibly damaging	0.95
R0281:Ankrd11	UTSW	8	122,895,568 (GRCm38)	missense	probably benign	0.01
R0450:Ankrd11	UTSW	8	122,892,175 (GRCm38)	missense	possibly damaging	0.95
R0481:Ankrd11	UTSW	8	122,900,036 (GRCm38)	missense	probably damaging	1.00
R0542:Ankrd11	UTSW	8	122,895,770 (GRCm38)	missense	probably damaging	0.99
R0606:Ankrd11	UTSW	8	122,892,832 (GRCm38)	missense	probably benign	0.04
R0702:Ankrd11	UTSW	8	122,889,766 (GRCm38)	missense	probably damaging	1.00
R0730:Ankrd11	UTSW	8	122,891,953 (GRCm38)	missense	probably damaging	1.00
R0737:Ankrd11	UTSW	8	122,895,836 (GRCm38)	missense	probably damaging	0.99
R1401:Ankrd11	UTSW	8	122,893,050 (GRCm38)	missense	probably benign	0.23
R1464:Ankrd11	UTSW	8	122,892,724 (GRCm38)	missense	probably damaging	1.00
R1464:Ankrd11	UTSW	8	122,892,724 (GRCm38)	missense	probably damaging	1.00
R1470:Ankrd11	UTSW	8	122,899,724 (GRCm38)	missense	probably damaging	0.98
R1470:Ankrd11	UTSW	8	122,899,724 (GRCm38)	missense	probably damaging	0.98
R1641:Ankrd11	UTSW	8	122,891,746 (GRCm38)	missense	probably benign	0.03
R1950:Ankrd11	UTSW	8	122,889,869 (GRCm38)	missense	probably damaging	1.00
R2004:Ankrd11	UTSW	8	122,902,422 (GRCm38)	critical splice donor site	probably null
R2401:Ankrd11	UTSW	8	122,908,734 (GRCm38)	nonsense	probably null
R2425:Ankrd11	UTSW	8	122,893,163 (GRCm38)	missense	possibly damaging	0.86
R2830:Ankrd11	UTSW	8	122,892,196 (GRCm38)	missense	probably damaging	1.00
R2910:Ankrd11	UTSW	8	122,908,798 (GRCm38)	missense	probably damaging	1.00
R2911:Ankrd11	UTSW	8	122,908,798 (GRCm38)	missense	probably damaging	1.00
R3736:Ankrd11	UTSW	8	122,891,785 (GRCm38)	missense	probably damaging	0.97
R3738:Ankrd11	UTSW	8	122,896,715 (GRCm38)	unclassified	probably benign
R3739:Ankrd11	UTSW	8	122,896,715 (GRCm38)	unclassified	probably benign
R3813:Ankrd11	UTSW	8	122,891,378 (GRCm38)	missense	probably benign
R4012:Ankrd11	UTSW	8	122,892,417 (GRCm38)	missense	probably damaging	0.98
R4183:Ankrd11	UTSW	8	122,899,676 (GRCm38)	missense	possibly damaging	0.88
R4213:Ankrd11	UTSW	8	122,891,026 (GRCm38)	missense	probably benign	0.00
R4469:Ankrd11	UTSW	8	122,896,587 (GRCm38)	missense	probably damaging	1.00
R4482:Ankrd11	UTSW	8	122,893,489 (GRCm38)	missense	probably damaging	1.00
R4935:Ankrd11	UTSW	8	122,900,183 (GRCm38)	missense	probably benign	0.02
R4940:Ankrd11	UTSW	8	122,889,821 (GRCm38)	missense	probably damaging	1.00
R5145:Ankrd11	UTSW	8	122,891,204 (GRCm38)	utr 3 prime	probably benign
R5154:Ankrd11	UTSW	8	122,893,139 (GRCm38)	missense	probably damaging	1.00
R5230:Ankrd11	UTSW	8	122,890,477 (GRCm38)	missense	probably benign	0.11
R5283:Ankrd11	UTSW	8	122,884,182 (GRCm38)	missense	probably damaging	1.00
R5377:Ankrd11	UTSW	8	122,893,714 (GRCm38)	splice site	probably null
R5513:Ankrd11	UTSW	8	122,892,520 (GRCm38)	missense	probably benign	0.38
R5518:Ankrd11	UTSW	8	122,890,994 (GRCm38)	missense	possibly damaging	0.93
R5549:Ankrd11	UTSW	8	122,890,378 (GRCm38)	missense	probably benign	0.02
R5579:Ankrd11	UTSW	8	122,884,231 (GRCm38)	missense	probably damaging	0.97
R5595:Ankrd11	UTSW	8	122,894,304 (GRCm38)	nonsense	probably null
R5650:Ankrd11	UTSW	8	122,887,397 (GRCm38)	missense	probably damaging	0.99
R5717:Ankrd11	UTSW	8	122,892,638 (GRCm38)	missense	possibly damaging	0.92
R5753:Ankrd11	UTSW	8	122,895,304 (GRCm38)	missense	possibly damaging	0.90
R5782:Ankrd11	UTSW	8	122,900,017 (GRCm38)	missense	probably damaging	1.00
R5812:Ankrd11	UTSW	8	122,893,805 (GRCm38)	splice site	probably null
R5823:Ankrd11	UTSW	8	122,895,790 (GRCm38)	missense	probably benign	0.12
R5900:Ankrd11	UTSW	8	122,891,066 (GRCm38)	missense	probably benign	0.00
R5975:Ankrd11	UTSW	8	122,889,749 (GRCm38)	missense	possibly damaging	0.93
R5979:Ankrd11	UTSW	8	122,892,400 (GRCm38)	missense	probably damaging	1.00
R6000:Ankrd11	UTSW	8	122,891,195 (GRCm38)	missense	possibly damaging	0.73
R6145:Ankrd11	UTSW	8	122,892,661 (GRCm38)	missense	probably damaging	1.00
R6252:Ankrd11	UTSW	8	122,893,822 (GRCm38)	missense	possibly damaging	0.87
R6302:Ankrd11	UTSW	8	122,889,989 (GRCm38)	missense	probably benign
R6457:Ankrd11	UTSW	8	122,908,764 (GRCm38)	missense	probably damaging	1.00
R6513:Ankrd11	UTSW	8	122,890,180 (GRCm38)	missense	probably benign	0.02
R6582:Ankrd11	UTSW	8	122,891,629 (GRCm38)	missense	probably benign	0.00
R6738:Ankrd11	UTSW	8	122,891,921 (GRCm38)	missense	probably damaging	0.99
R6865:Ankrd11	UTSW	8	122,894,944 (GRCm38)	missense	probably benign	0.41
R6913:Ankrd11	UTSW	8	122,894,911 (GRCm38)	missense	probably benign	0.01
R7101:Ankrd11	UTSW	8	122,895,455 (GRCm38)	missense	probably benign	0.35
R7116:Ankrd11	UTSW	8	122,896,130 (GRCm38)	missense	probably damaging	1.00
R7477:Ankrd11	UTSW	8	122,894,385 (GRCm38)	missense	possibly damaging	0.91
R7534:Ankrd11	UTSW	8	122,894,410 (GRCm38)	missense	probably damaging	1.00
R7555:Ankrd11	UTSW	8	122,887,406 (GRCm38)	missense	probably damaging	0.99
R7627:Ankrd11	UTSW	8	122,890,951 (GRCm38)	missense	possibly damaging	0.63
R7658:Ankrd11	UTSW	8	122,893,664 (GRCm38)	missense	probably benign
R7721:Ankrd11	UTSW	8	122,894,759 (GRCm38)	missense	probably damaging	1.00
R7731:Ankrd11	UTSW	8	122,895,433 (GRCm38)	missense	probably benign	0.12
R7792:Ankrd11	UTSW	8	122,884,231 (GRCm38)	missense	probably damaging	0.97
R7924:Ankrd11	UTSW	8	122,895,902 (GRCm38)	missense	possibly damaging	0.95
R7939:Ankrd11	UTSW	8	122,891,073 (GRCm38)	missense	probably damaging	1.00
R8222:Ankrd11	UTSW	8	122,895,608 (GRCm38)	missense	probably damaging	0.98
R8362:Ankrd11	UTSW	8	122,892,058 (GRCm38)	missense	probably damaging	0.96
R8430:Ankrd11	UTSW	8	122,893,366 (GRCm38)	missense	probably benign	0.01
R8511:Ankrd11	UTSW	8	122,899,729 (GRCm38)	missense
R8726:Ankrd11	UTSW	8	122,894,026 (GRCm38)	missense	possibly damaging	0.90
R8888:Ankrd11	UTSW	8	122,894,275 (GRCm38)	missense	possibly damaging	0.87
R8895:Ankrd11	UTSW	8	122,894,275 (GRCm38)	missense	possibly damaging	0.87
R8928:Ankrd11	UTSW	8	122,895,979 (GRCm38)	missense	probably damaging	0.99
R8930:Ankrd11	UTSW	8	122,895,979 (GRCm38)	missense	probably damaging	0.99
R8931:Ankrd11	UTSW	8	122,895,979 (GRCm38)	missense	probably damaging	0.99
R8936:Ankrd11	UTSW	8	122,895,101 (GRCm38)	missense	possibly damaging	0.69
R9018:Ankrd11	UTSW	8	122,895,512 (GRCm38)	missense	probably damaging	1.00
R9113:Ankrd11	UTSW	8	122,887,333 (GRCm38)	missense	possibly damaging	0.60
R9399:Ankrd11	UTSW	8	122,891,440 (GRCm38)	missense	probably benign
R9644:Ankrd11	UTSW	8	122,890,943 (GRCm38)	missense	probably benign	0.00
R9645:Ankrd11	UTSW	8	122,890,943 (GRCm38)	missense	probably benign	0.00
R9647:Ankrd11	UTSW	8	122,890,943 (GRCm38)	missense	probably benign	0.00
R9683:Ankrd11	UTSW	8	122,890,943 (GRCm38)	missense	probably benign	0.00
RF019:Ankrd11	UTSW	8	122,896,634 (GRCm38)	missense	probably damaging	1.00
Z1176:Ankrd11	UTSW	8	122,895,803 (GRCm38)	missense	possibly damaging	0.68
Z1177:Ankrd11	UTSW	8	122,900,142 (GRCm38)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- CATGCACTGAATGGCACTG -3'
(R):5'- TACTTGTAGGGTTCACGTGCAG -3'

Sequencing Primer
(F):5'- GGCAATGAACCCGAAGAATCTCTTG -3'
(R):5'- AGGGTTCACGTGCAGCTCTG -3'

Posted On

2020-01-23