Incidental Mutation 'R8052:Rusc2'
| ID |
619095 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Rusc2
|
| Ensembl Gene |
ENSMUSG00000035969 |
| Gene Name |
RUN and SH3 domain containing 2 |
| Synonyms |
|
| MMRRC Submission |
067489-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.158)
|
| Stock # |
R8052 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
4 |
| Chromosomal Location |
43381979-43427088 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 43421851 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Phenylalanine to Serine
at position 757
(F757S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000038379
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000035645]
[ENSMUST00000098106]
[ENSMUST00000131668]
[ENSMUST00000149221]
[ENSMUST00000173682]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000035645
AA Change: F757S
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000038379
Gene: ENSMUSG00000035969
AA Change: F757S
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
39 |
47 |
N/A |
INTRINSIC |
|
low complexity region
|
212 |
230 |
N/A |
INTRINSIC |
|
low complexity region
|
253 |
265 |
N/A |
INTRINSIC |
|
low complexity region
|
411 |
427 |
N/A |
INTRINSIC |
|
low complexity region
|
435 |
448 |
N/A |
INTRINSIC |
|
low complexity region
|
530 |
544 |
N/A |
INTRINSIC |
|
low complexity region
|
600 |
617 |
N/A |
INTRINSIC |
|
low complexity region
|
795 |
809 |
N/A |
INTRINSIC |
|
RUN
|
1109 |
1177 |
3.66e-21 |
SMART |
|
low complexity region
|
1235 |
1260 |
N/A |
INTRINSIC |
|
low complexity region
|
1289 |
1324 |
N/A |
INTRINSIC |
|
low complexity region
|
1330 |
1341 |
N/A |
INTRINSIC |
|
SH3
|
1457 |
1512 |
7.4e-11 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000098106
AA Change: F757S
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000095710
Gene: ENSMUSG00000035969
AA Change: F757S
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
39 |
47 |
N/A |
INTRINSIC |
|
low complexity region
|
212 |
230 |
N/A |
INTRINSIC |
|
low complexity region
|
253 |
265 |
N/A |
INTRINSIC |
|
low complexity region
|
411 |
427 |
N/A |
INTRINSIC |
|
low complexity region
|
435 |
448 |
N/A |
INTRINSIC |
|
low complexity region
|
530 |
544 |
N/A |
INTRINSIC |
|
low complexity region
|
600 |
617 |
N/A |
INTRINSIC |
|
low complexity region
|
795 |
809 |
N/A |
INTRINSIC |
|
RUN
|
1109 |
1177 |
3.66e-21 |
SMART |
|
low complexity region
|
1235 |
1260 |
N/A |
INTRINSIC |
|
low complexity region
|
1289 |
1324 |
N/A |
INTRINSIC |
|
low complexity region
|
1330 |
1341 |
N/A |
INTRINSIC |
|
SH3
|
1457 |
1512 |
7.4e-11 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000131668
AA Change: F757S
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000118528
Gene: ENSMUSG00000035969
AA Change: F757S
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
39 |
47 |
N/A |
INTRINSIC |
|
low complexity region
|
212 |
230 |
N/A |
INTRINSIC |
|
low complexity region
|
253 |
265 |
N/A |
INTRINSIC |
|
low complexity region
|
411 |
427 |
N/A |
INTRINSIC |
|
low complexity region
|
435 |
448 |
N/A |
INTRINSIC |
|
low complexity region
|
530 |
544 |
N/A |
INTRINSIC |
|
low complexity region
|
600 |
617 |
N/A |
INTRINSIC |
|
low complexity region
|
795 |
809 |
N/A |
INTRINSIC |
|
RUN
|
1109 |
1177 |
3.66e-21 |
SMART |
|
low complexity region
|
1235 |
1260 |
N/A |
INTRINSIC |
|
low complexity region
|
1289 |
1324 |
N/A |
INTRINSIC |
|
low complexity region
|
1330 |
1341 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000149221
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000173682
AA Change: S652P
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000133715
Gene: ENSMUSG00000035969
AA Change: S652P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
39 |
47 |
N/A |
INTRINSIC |
|
low complexity region
|
212 |
230 |
N/A |
INTRINSIC |
|
low complexity region
|
253 |
265 |
N/A |
INTRINSIC |
|
low complexity region
|
411 |
427 |
N/A |
INTRINSIC |
|
low complexity region
|
435 |
448 |
N/A |
INTRINSIC |
|
low complexity region
|
530 |
544 |
N/A |
INTRINSIC |
|
low complexity region
|
685 |
703 |
N/A |
INTRINSIC |
|
low complexity region
|
733 |
740 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.5%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a RUN and SH3 domain containing protein that interacts with Rab1b and Rab1-binding protein GM130. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jun 2012]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 72 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700123L14Rik |
TCC |
TCCGCC |
6: 96,165,097 (GRCm38) |
|
probably benign |
Het |
| 1700123L14Rik |
TCC |
TCCCCC |
6: 96,165,103 (GRCm38) |
|
probably benign |
Het |
| 2010111I01Rik |
G |
A |
13: 63,068,251 (GRCm38) |
V446I |
probably damaging |
Het |
| Abi1 |
T |
C |
2: 22,953,543 (GRCm38) |
T297A |
probably benign |
Het |
| Acadl |
G |
T |
1: 66,853,178 (GRCm38) |
T162K |
probably benign |
Het |
| Aldoart2 |
A |
T |
12: 55,565,751 (GRCm38) |
I154F |
probably damaging |
Het |
| Alkbh8 |
G |
A |
9: 3,385,478 (GRCm38) |
R625H |
probably damaging |
Het |
| Ankrd31 |
T |
A |
13: 96,832,528 (GRCm38) |
V891E |
probably benign |
Het |
| Atp8b5 |
C |
T |
4: 43,356,982 (GRCm38) |
R577* |
probably null |
Het |
| Capn3 |
G |
T |
2: 120,486,386 (GRCm38) |
E285D |
probably benign |
Het |
| Cd79b |
G |
T |
11: 106,313,700 (GRCm38) |
P87T |
probably damaging |
Het |
| Celsr2 |
T |
G |
3: 108,412,655 (GRCm38) |
D947A |
probably damaging |
Het |
| Csmd3 |
A |
C |
15: 47,706,387 (GRCm38) |
S1213R |
|
Het |
| Cyp2j5 |
T |
C |
4: 96,664,004 (GRCm38) |
M3V |
probably benign |
Het |
| Ddi1 |
C |
T |
9: 6,265,787 (GRCm38) |
R194K |
probably benign |
Het |
| Decr1 |
T |
C |
4: 15,933,019 (GRCm38) |
K49R |
probably benign |
Het |
| Dnah10 |
A |
C |
5: 124,828,511 (GRCm38) |
E4130A |
probably benign |
Het |
| Dst |
A |
G |
1: 34,284,363 (GRCm38) |
D4648G |
probably damaging |
Het |
| Ecd |
A |
G |
14: 20,329,952 (GRCm38) |
|
probably null |
Het |
| Erbin |
A |
T |
13: 103,834,356 (GRCm38) |
Y917* |
probably null |
Het |
| Evpl |
T |
C |
11: 116,223,163 (GRCm38) |
K1234E |
probably benign |
Het |
| F11r |
T |
A |
1: 171,461,623 (GRCm38) |
Y218N |
possibly damaging |
Het |
| Fam43a |
C |
G |
16: 30,601,804 (GRCm38) |
T402S |
probably benign |
Het |
| Frem2 |
T |
C |
3: 53,549,643 (GRCm38) |
N2096S |
probably benign |
Het |
| Gm7697 |
A |
T |
8: 69,522,752 (GRCm38) |
Y21N |
possibly damaging |
Het |
| Gpd2 |
T |
A |
2: 57,306,950 (GRCm38) |
Y172* |
probably null |
Het |
| Hscb |
A |
G |
5: 110,835,978 (GRCm38) |
V90A |
probably benign |
Het |
| Iqgap2 |
T |
C |
13: 95,657,879 (GRCm38) |
D1195G |
probably damaging |
Het |
| Map2k2 |
T |
C |
10: 81,115,066 (GRCm38) |
I115T |
probably damaging |
Het |
| Mast2 |
C |
T |
4: 116,312,975 (GRCm38) |
R707H |
probably damaging |
Het |
| Mindy4 |
A |
G |
6: 55,300,992 (GRCm38) |
N607S |
probably damaging |
Het |
| Mrpl9 |
T |
A |
3: 94,443,743 (GRCm38) |
Y77N |
probably damaging |
Het |
| Muc16 |
G |
A |
9: 18,659,051 (GRCm38) |
T724I |
unknown |
Het |
| Nat3 |
A |
T |
8: 67,547,826 (GRCm38) |
Y119F |
possibly damaging |
Het |
| Nol7 |
T |
C |
13: 43,401,514 (GRCm38) |
S208P |
probably damaging |
Het |
| Notch3 |
A |
T |
17: 32,146,571 (GRCm38) |
C1056S |
probably damaging |
Het |
| Olfr1039 |
A |
T |
2: 86,131,377 (GRCm38) |
Y95* |
probably null |
Het |
| Olfr146 |
G |
T |
9: 39,019,487 (GRCm38) |
T18K |
probably damaging |
Het |
| Olfr399 |
T |
A |
11: 74,054,475 (GRCm38) |
I95F |
probably benign |
Het |
| Olfr71 |
A |
T |
4: 43,705,884 (GRCm38) |
V228E |
probably damaging |
Het |
| Osbpl3 |
A |
C |
6: 50,346,015 (GRCm38) |
L288R |
probably damaging |
Het |
| Oscp1 |
A |
C |
4: 126,088,323 (GRCm38) |
D352A |
possibly damaging |
Het |
| Pcdh9 |
G |
A |
14: 93,885,786 (GRCm38) |
R983C |
probably benign |
Het |
| Pcdhgb8 |
T |
C |
18: 37,763,502 (GRCm38) |
S542P |
probably benign |
Het |
| Pi4ka |
T |
C |
16: 17,356,166 (GRCm38) |
T490A |
|
Het |
| Pkd1l1 |
A |
T |
11: 8,947,315 (GRCm38) |
D531E |
|
Het |
| Prr3 |
G |
T |
17: 35,979,161 (GRCm38) |
D26E |
possibly damaging |
Het |
| Psmd8 |
T |
C |
7: 29,180,576 (GRCm38) |
K24E |
probably benign |
Het |
| Rasgrp4 |
G |
A |
7: 29,149,937 (GRCm38) |
C583Y |
probably damaging |
Het |
| Rest |
A |
G |
5: 77,268,324 (GRCm38) |
I128M |
probably benign |
Het |
| Rftn1 |
A |
T |
17: 50,086,579 (GRCm38) |
F144I |
probably damaging |
Het |
| Ryr1 |
A |
G |
7: 29,083,385 (GRCm38) |
S1942P |
probably benign |
Het |
| Sdk2 |
C |
T |
11: 113,854,351 (GRCm38) |
R706Q |
probably damaging |
Het |
| Sergef |
G |
T |
7: 46,614,638 (GRCm38) |
T275K |
probably damaging |
Het |
| Serpina10 |
T |
C |
12: 103,628,310 (GRCm38) |
T217A |
probably damaging |
Het |
| Shd |
G |
C |
17: 55,976,235 (GRCm38) |
S288T |
probably damaging |
Het |
| Siglec15 |
C |
A |
18: 78,048,588 (GRCm38) |
A133S |
possibly damaging |
Het |
| Stat4 |
C |
T |
1: 52,079,773 (GRCm38) |
P325L |
probably damaging |
Het |
| Syt8 |
G |
A |
7: 142,440,144 (GRCm38) |
G344D |
probably damaging |
Het |
| Tes |
A |
G |
6: 17,097,292 (GRCm38) |
E133G |
probably benign |
Het |
| Tmprss2 |
T |
C |
16: 97,568,416 (GRCm38) |
Y386C |
probably damaging |
Het |
| Tnfrsf11b |
A |
T |
15: 54,252,106 (GRCm38) |
L365Q |
probably damaging |
Het |
| Tns1 |
T |
A |
1: 73,953,437 (GRCm38) |
D67V |
probably damaging |
Het |
| Tns2 |
T |
C |
15: 102,112,845 (GRCm38) |
S982P |
probably damaging |
Het |
| Tpcn2 |
A |
T |
7: 145,260,946 (GRCm38) |
F473I |
probably benign |
Het |
| Tsg101 |
A |
T |
7: 46,892,509 (GRCm38) |
I232N |
probably damaging |
Het |
| Ttc3 |
T |
C |
16: 94,467,989 (GRCm38) |
S1977P |
probably benign |
Het |
| Ttll11 |
T |
A |
2: 35,979,515 (GRCm38) |
E37V |
unknown |
Het |
| Ttn |
A |
T |
2: 76,818,816 (GRCm38) |
V12716E |
possibly damaging |
Het |
| Vmn2r70 |
A |
C |
7: 85,563,715 (GRCm38) |
S495A |
probably benign |
Het |
| Zfp974 |
A |
G |
7: 27,911,272 (GRCm38) |
C343R |
probably damaging |
Het |
| Zfy1 |
A |
T |
Y: 726,004 (GRCm38) |
I587N |
possibly damaging |
Het |
|
| Other mutations in Rusc2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01358:Rusc2
|
APN |
4 |
43,426,116 (GRCm38) |
missense |
probably damaging |
0.97 |
|
IGL01474:Rusc2
|
APN |
4 |
43,416,434 (GRCm38) |
missense |
probably damaging |
0.98 |
|
IGL01541:Rusc2
|
APN |
4 |
43,415,840 (GRCm38) |
missense |
probably benign |
0.08 |
|
IGL01628:Rusc2
|
APN |
4 |
43,425,729 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01969:Rusc2
|
APN |
4 |
43,415,738 (GRCm38) |
missense |
probably benign |
0.02 |
|
IGL02030:Rusc2
|
APN |
4 |
43,416,095 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
IGL02079:Rusc2
|
APN |
4 |
43,425,668 (GRCm38) |
missense |
probably benign |
|
|
IGL02115:Rusc2
|
APN |
4 |
43,426,136 (GRCm38) |
splice site |
probably benign |
|
|
IGL02122:Rusc2
|
APN |
4 |
43,421,685 (GRCm38) |
missense |
possibly damaging |
0.67 |
|
IGL02350:Rusc2
|
APN |
4 |
43,425,351 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
IGL02357:Rusc2
|
APN |
4 |
43,425,351 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
IGL02437:Rusc2
|
APN |
4 |
43,415,545 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02930:Rusc2
|
APN |
4 |
43,416,376 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL03154:Rusc2
|
APN |
4 |
43,425,806 (GRCm38) |
missense |
probably benign |
0.00 |
|
P0026:Rusc2
|
UTSW |
4 |
43,415,840 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R0036:Rusc2
|
UTSW |
4 |
43,424,009 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0068:Rusc2
|
UTSW |
4 |
43,424,100 (GRCm38) |
splice site |
probably benign |
|
|
R0068:Rusc2
|
UTSW |
4 |
43,424,100 (GRCm38) |
splice site |
probably benign |
|
|
R0114:Rusc2
|
UTSW |
4 |
43,422,055 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0255:Rusc2
|
UTSW |
4 |
43,423,954 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0471:Rusc2
|
UTSW |
4 |
43,425,486 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1381:Rusc2
|
UTSW |
4 |
43,416,137 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1413:Rusc2
|
UTSW |
4 |
43,416,568 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1416:Rusc2
|
UTSW |
4 |
43,421,617 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
R1731:Rusc2
|
UTSW |
4 |
43,426,046 (GRCm38) |
missense |
probably benign |
|
|
R1864:Rusc2
|
UTSW |
4 |
43,421,719 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
R1897:Rusc2
|
UTSW |
4 |
43,421,749 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2010:Rusc2
|
UTSW |
4 |
43,415,212 (GRCm38) |
missense |
probably benign |
0.06 |
|
R2212:Rusc2
|
UTSW |
4 |
43,415,935 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2275:Rusc2
|
UTSW |
4 |
43,416,260 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2885:Rusc2
|
UTSW |
4 |
43,415,456 (GRCm38) |
missense |
probably benign |
0.28 |
|
R2886:Rusc2
|
UTSW |
4 |
43,415,456 (GRCm38) |
missense |
probably benign |
0.28 |
|
R3412:Rusc2
|
UTSW |
4 |
43,415,935 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3413:Rusc2
|
UTSW |
4 |
43,415,935 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3414:Rusc2
|
UTSW |
4 |
43,415,935 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3852:Rusc2
|
UTSW |
4 |
43,416,424 (GRCm38) |
missense |
probably benign |
0.45 |
|
R4135:Rusc2
|
UTSW |
4 |
43,425,563 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
R4272:Rusc2
|
UTSW |
4 |
43,415,533 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4574:Rusc2
|
UTSW |
4 |
43,416,080 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4888:Rusc2
|
UTSW |
4 |
43,423,942 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5010:Rusc2
|
UTSW |
4 |
43,415,926 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5071:Rusc2
|
UTSW |
4 |
43,415,240 (GRCm38) |
missense |
probably benign |
0.05 |
|
R5131:Rusc2
|
UTSW |
4 |
43,414,948 (GRCm38) |
missense |
probably benign |
0.03 |
|
R5177:Rusc2
|
UTSW |
4 |
43,421,805 (GRCm38) |
splice site |
probably null |
|
|
R5540:Rusc2
|
UTSW |
4 |
43,423,975 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5561:Rusc2
|
UTSW |
4 |
43,415,932 (GRCm38) |
nonsense |
probably null |
|
|
R5628:Rusc2
|
UTSW |
4 |
43,425,348 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5645:Rusc2
|
UTSW |
4 |
43,425,758 (GRCm38) |
missense |
probably benign |
0.06 |
|
R6129:Rusc2
|
UTSW |
4 |
43,424,271 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6362:Rusc2
|
UTSW |
4 |
43,416,416 (GRCm38) |
missense |
probably benign |
0.30 |
|
R6633:Rusc2
|
UTSW |
4 |
43,414,852 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R6980:Rusc2
|
UTSW |
4 |
43,422,846 (GRCm38) |
missense |
probably benign |
0.35 |
|
R7491:Rusc2
|
UTSW |
4 |
43,426,528 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7641:Rusc2
|
UTSW |
4 |
43,425,335 (GRCm38) |
missense |
possibly damaging |
0.84 |
|
R7698:Rusc2
|
UTSW |
4 |
43,414,900 (GRCm38) |
nonsense |
probably null |
|
|
R7710:Rusc2
|
UTSW |
4 |
43,416,119 (GRCm38) |
missense |
probably benign |
0.07 |
|
R8061:Rusc2
|
UTSW |
4 |
43,422,492 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8127:Rusc2
|
UTSW |
4 |
43,423,747 (GRCm38) |
missense |
possibly damaging |
0.54 |
|
R8319:Rusc2
|
UTSW |
4 |
43,425,378 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8355:Rusc2
|
UTSW |
4 |
43,422,846 (GRCm38) |
missense |
probably benign |
0.35 |
|
R8397:Rusc2
|
UTSW |
4 |
43,424,206 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R8455:Rusc2
|
UTSW |
4 |
43,422,846 (GRCm38) |
missense |
probably benign |
0.35 |
|
R8553:Rusc2
|
UTSW |
4 |
43,416,508 (GRCm38) |
missense |
probably benign |
0.05 |
|
R8725:Rusc2
|
UTSW |
4 |
43,401,351 (GRCm38) |
intron |
probably benign |
|
|
R8725:Rusc2
|
UTSW |
4 |
43,415,396 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R8727:Rusc2
|
UTSW |
4 |
43,401,351 (GRCm38) |
intron |
probably benign |
|
|
R8834:Rusc2
|
UTSW |
4 |
43,416,431 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R9295:Rusc2
|
UTSW |
4 |
43,416,382 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R9483:Rusc2
|
UTSW |
4 |
43,415,897 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R9666:Rusc2
|
UTSW |
4 |
43,416,262 (GRCm38) |
missense |
probably benign |
0.21 |
|
R9705:Rusc2
|
UTSW |
4 |
43,424,936 (GRCm38) |
missense |
probably benign |
0.00 |
|
X0025:Rusc2
|
UTSW |
4 |
43,422,226 (GRCm38) |
missense |
probably benign |
0.00 |
|
X0066:Rusc2
|
UTSW |
4 |
43,422,204 (GRCm38) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TTCGCTACAGCAAGGAACAGAG -3'
(R):5'- ATACACTGTCGGCTGCTGTG -3'
Sequencing Primer
(F):5'- TACCGATCCAGCCGTTCGTG -3'
(R):5'- TGTGCCCTGCTCTGGAG -3'
|
| Posted On |
2020-01-23 |
Incidental Mutation