Incidental Mutation 'R8058:Fan1'
| ID |
619542 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Fan1
|
| Ensembl Gene |
ENSMUSG00000033458 |
| Gene Name |
FANCD2/FANCI-associated nuclease 1 |
| Synonyms |
Mtmr15, 6030441H18Rik |
| MMRRC Submission |
067495-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R8058 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
7 |
| Chromosomal Location |
63996506-64023843 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 64022234 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Tyrosine
at position 340
(N340Y)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000130012
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000032735]
[ENSMUST00000163289]
|
| AlphaFold |
Q69ZT1 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000032735
|
| SMART Domains |
Protein: ENSMUSP00000032735
Gene: ENSMUSG00000030521
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Mpp10
|
20 |
654 |
6.9e-217 |
PFAM |
|
low complexity region
|
666 |
671 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000163289
AA Change: N340Y
PolyPhen 2
Score 0.974 (Sensitivity: 0.76; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000130012
Gene: ENSMUSG00000033458
AA Change: N340Y
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1ihga1
|
600 |
737 |
5e-5 |
SMART |
|
Blast:VRR_NUC
|
834 |
867 |
2e-12 |
BLAST |
|
VRR_NUC
|
896 |
1011 |
1.99e-37 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000206047
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000206329
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000206730
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000206778
|
| Meta Mutation Damage Score |
0.1011 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.8%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene plays a role in DNA interstrand cross-link repair and encodes a protein with 5' flap endonuclease and 5'-3' exonuclease activity. Mutations in this gene cause karyomegalic interstitial nephritis. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Feb 2016]
PHENOTYPE: Mice homozygous for mutations in this gene display renal tubular karyomegaly with polyploidy and defects in interstrand cross-link DNA repair. Some homozygous mice also display hepatocyte karyomegaly and liver dysfunction. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 78 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca1 |
C |
T |
4: 53,081,954 (GRCm39) |
D769N |
possibly damaging |
Het |
| Abcb6 |
A |
G |
1: 75,156,653 (GRCm39) |
L37P |
possibly damaging |
Het |
| Abcg1 |
G |
T |
17: 31,324,504 (GRCm39) |
A250S |
probably benign |
Het |
| Acsf3 |
C |
T |
8: 123,540,373 (GRCm39) |
H524Y |
possibly damaging |
Het |
| Agbl4 |
A |
G |
4: 110,518,039 (GRCm39) |
K110R |
unknown |
Het |
| Arfgap2 |
G |
A |
2: 91,096,644 (GRCm39) |
|
probably null |
Het |
| B4galt4 |
T |
C |
16: 38,586,383 (GRCm39) |
|
probably null |
Het |
| Bex6 |
G |
T |
16: 32,005,224 (GRCm39) |
D11Y |
probably damaging |
Het |
| Bhlhe40 |
TG |
TGG |
6: 108,641,818 (GRCm39) |
254 |
probably null |
Het |
| C8b |
A |
T |
4: 104,647,811 (GRCm39) |
D334V |
probably damaging |
Het |
| Capn11 |
T |
C |
17: 45,954,681 (GRCm39) |
Q152R |
probably null |
Het |
| Ccdc171 |
C |
A |
4: 83,499,003 (GRCm39) |
Q234K |
probably damaging |
Het |
| Cemip2 |
C |
A |
19: 21,829,695 (GRCm39) |
A1268E |
probably benign |
Het |
| Clec2h |
A |
G |
6: 128,650,966 (GRCm39) |
D82G |
probably benign |
Het |
| Creld2 |
A |
G |
15: 88,710,632 (GRCm39) |
D349G |
probably damaging |
Het |
| D430041D05Rik |
A |
G |
2: 103,979,128 (GRCm39) |
*1415Q |
probably null |
Het |
| Dnmt3a |
T |
C |
12: 3,952,768 (GRCm39) |
V755A |
possibly damaging |
Het |
| Doc2a |
G |
T |
7: 126,450,164 (GRCm39) |
V201L |
probably benign |
Het |
| Fbn1 |
G |
T |
2: 125,193,889 (GRCm39) |
D1359E |
possibly damaging |
Het |
| Fcnb |
T |
C |
2: 27,969,707 (GRCm39) |
Y120C |
probably damaging |
Het |
| Fras1 |
T |
A |
5: 96,842,778 (GRCm39) |
D1665E |
probably benign |
Het |
| Fry |
A |
T |
5: 150,419,232 (GRCm39) |
D524V |
|
Het |
| Garem1 |
A |
G |
18: 21,281,621 (GRCm39) |
L245P |
probably damaging |
Het |
| Gdf6 |
A |
G |
4: 9,859,712 (GRCm39) |
S265G |
probably benign |
Het |
| Gm5591 |
T |
C |
7: 38,218,363 (GRCm39) |
I837V |
probably benign |
Het |
| Gpr61 |
T |
C |
3: 108,058,211 (GRCm39) |
Y150C |
probably damaging |
Het |
| Grin2b |
A |
T |
6: 135,710,225 (GRCm39) |
L1107Q |
probably damaging |
Het |
| Helb |
A |
G |
10: 119,941,483 (GRCm39) |
S402P |
probably benign |
Het |
| Htt |
A |
G |
5: 34,977,444 (GRCm39) |
T777A |
probably benign |
Het |
| Iffo2 |
A |
G |
4: 139,341,164 (GRCm39) |
D383G |
probably benign |
Het |
| Ikzf3 |
G |
T |
11: 98,407,753 (GRCm39) |
Y29* |
probably null |
Het |
| Ints2 |
A |
T |
11: 86,146,179 (GRCm39) |
M143K |
probably benign |
Het |
| Jmjd1c |
T |
C |
10: 67,090,274 (GRCm39) |
V2292A |
not run |
Het |
| Katnip |
A |
G |
7: 125,442,188 (GRCm39) |
E725G |
probably benign |
Het |
| Lamb1 |
C |
A |
12: 31,353,046 (GRCm39) |
Q916K |
probably benign |
Het |
| Lrrtm4 |
G |
A |
6: 79,999,528 (GRCm39) |
M313I |
probably benign |
Het |
| Lum |
A |
G |
10: 97,404,425 (GRCm39) |
I107V |
probably benign |
Het |
| Ly6h |
T |
C |
15: 75,437,061 (GRCm39) |
E126G |
probably benign |
Het |
| Map3k5 |
G |
A |
10: 20,007,860 (GRCm39) |
V1230M |
probably damaging |
Het |
| Mcoln1 |
T |
C |
8: 3,558,378 (GRCm39) |
F211L |
probably benign |
Het |
| Mink1 |
G |
A |
11: 70,494,594 (GRCm39) |
W258* |
probably null |
Het |
| Muc16 |
G |
T |
9: 18,571,298 (GRCm39) |
S407* |
probably null |
Het |
| Ngef |
G |
A |
1: 87,473,744 (GRCm39) |
Q13* |
probably null |
Het |
| Nxpe5 |
T |
A |
5: 138,237,573 (GRCm39) |
Y44* |
probably null |
Het |
| Or13d1 |
T |
A |
4: 52,971,106 (GRCm39) |
L162M |
probably benign |
Het |
| Or4a77 |
A |
G |
2: 89,487,671 (GRCm39) |
V38A |
probably benign |
Het |
| Or5t9 |
A |
G |
2: 86,660,052 (GRCm39) |
R319G |
probably benign |
Het |
| Or7e178 |
T |
A |
9: 20,225,476 (GRCm39) |
I247F |
probably damaging |
Het |
| Or8g24 |
A |
T |
9: 38,989,862 (GRCm39) |
Y60N |
probably damaging |
Het |
| Or8h8 |
C |
A |
2: 86,753,151 (GRCm39) |
A242S |
probably benign |
Het |
| Orc3 |
C |
A |
4: 34,595,223 (GRCm39) |
E249* |
probably null |
Het |
| Otogl |
A |
T |
10: 107,598,287 (GRCm39) |
C2288S |
probably damaging |
Het |
| Pde1b |
A |
G |
15: 103,433,238 (GRCm39) |
E249G |
probably damaging |
Het |
| Phf2 |
T |
C |
13: 48,976,558 (GRCm39) |
E219G |
unknown |
Het |
| Rbm19 |
T |
A |
5: 120,278,440 (GRCm39) |
|
probably null |
Het |
| Rcc2 |
G |
A |
4: 140,429,586 (GRCm39) |
C40Y |
probably benign |
Het |
| Sbk2 |
A |
G |
7: 4,960,289 (GRCm39) |
Y294H |
possibly damaging |
Het |
| Selenoo |
T |
C |
15: 88,976,942 (GRCm39) |
I198T |
possibly damaging |
Het |
| Sema3f |
T |
C |
9: 107,559,800 (GRCm39) |
E729G |
probably benign |
Het |
| Serpinb1b |
A |
T |
13: 33,269,293 (GRCm39) |
T9S |
probably benign |
Het |
| Sfxn4 |
T |
C |
19: 60,832,690 (GRCm39) |
T235A |
probably damaging |
Het |
| Shc4 |
A |
T |
2: 125,491,154 (GRCm39) |
Y461* |
probably null |
Het |
| Slc22a15 |
T |
C |
3: 101,771,926 (GRCm39) |
D391G |
probably benign |
Het |
| Slc22a23 |
G |
T |
13: 34,489,167 (GRCm39) |
Y239* |
probably null |
Het |
| Slc24a2 |
G |
A |
4: 86,909,750 (GRCm39) |
A656V |
probably damaging |
Het |
| Slc2a5 |
A |
T |
4: 150,227,590 (GRCm39) |
I470F |
probably damaging |
Het |
| Sptbn4 |
T |
C |
7: 27,063,694 (GRCm39) |
E2249G |
possibly damaging |
Het |
| Tas2r139 |
A |
T |
6: 42,118,753 (GRCm39) |
Q295L |
probably benign |
Het |
| Tdrd7 |
C |
A |
4: 46,034,309 (GRCm39) |
S1051R |
probably benign |
Het |
| Tnfrsf18 |
G |
A |
4: 156,112,802 (GRCm39) |
A163T |
probably benign |
Het |
| Ube3b |
T |
C |
5: 114,544,846 (GRCm39) |
V596A |
possibly damaging |
Het |
| Vmn2r10 |
T |
A |
5: 109,149,955 (GRCm39) |
N363I |
probably benign |
Het |
| Vmn2r15 |
T |
A |
5: 109,440,956 (GRCm39) |
I301F |
probably damaging |
Het |
| Yod1 |
C |
T |
1: 130,646,806 (GRCm39) |
Q228* |
probably null |
Het |
| Zfp433 |
A |
T |
10: 81,556,124 (GRCm39) |
K209* |
probably null |
Het |
| Zfp865 |
G |
A |
7: 5,033,445 (GRCm39) |
V477I |
probably benign |
Het |
| Zfp937 |
T |
A |
2: 150,081,421 (GRCm39) |
Y484N |
probably benign |
Het |
| Zfp951 |
T |
G |
5: 104,962,312 (GRCm39) |
H418P |
probably damaging |
Het |
|
| Other mutations in Fan1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01648:Fan1
|
APN |
7 |
64,022,297 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01752:Fan1
|
APN |
7 |
64,022,542 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01971:Fan1
|
APN |
7 |
64,003,459 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02043:Fan1
|
APN |
7 |
64,021,367 (GRCm39) |
splice site |
probably null |
|
|
IGL02542:Fan1
|
APN |
7 |
64,014,408 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02731:Fan1
|
APN |
7 |
64,022,741 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
IGL03111:Fan1
|
APN |
7 |
63,999,816 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
hitched
|
UTSW |
7 |
64,014,377 (GRCm39) |
missense |
probably damaging |
1.00 |
|
stitched
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0270:Fan1
|
UTSW |
7 |
63,998,619 (GRCm39) |
missense |
probably benign |
0.26 |
|
R0632:Fan1
|
UTSW |
7 |
64,012,947 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R1714:Fan1
|
UTSW |
7 |
64,016,435 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1750:Fan1
|
UTSW |
7 |
64,022,761 (GRCm39) |
missense |
probably benign |
0.14 |
|
R1822:Fan1
|
UTSW |
7 |
64,022,554 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2031:Fan1
|
UTSW |
7 |
64,004,172 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2107:Fan1
|
UTSW |
7 |
64,016,536 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2126:Fan1
|
UTSW |
7 |
63,996,636 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2869:Fan1
|
UTSW |
7 |
64,012,938 (GRCm39) |
missense |
probably benign |
0.16 |
|
R2869:Fan1
|
UTSW |
7 |
64,012,938 (GRCm39) |
missense |
probably benign |
0.16 |
|
R2870:Fan1
|
UTSW |
7 |
64,012,938 (GRCm39) |
missense |
probably benign |
0.16 |
|
R2870:Fan1
|
UTSW |
7 |
64,012,938 (GRCm39) |
missense |
probably benign |
0.16 |
|
R2871:Fan1
|
UTSW |
7 |
64,012,938 (GRCm39) |
missense |
probably benign |
0.16 |
|
R2871:Fan1
|
UTSW |
7 |
64,012,938 (GRCm39) |
missense |
probably benign |
0.16 |
|
R2873:Fan1
|
UTSW |
7 |
64,012,938 (GRCm39) |
missense |
probably benign |
0.16 |
|
R3849:Fan1
|
UTSW |
7 |
64,022,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3850:Fan1
|
UTSW |
7 |
64,022,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3949:Fan1
|
UTSW |
7 |
64,021,292 (GRCm39) |
nonsense |
probably null |
|
|
R4007:Fan1
|
UTSW |
7 |
64,016,309 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4490:Fan1
|
UTSW |
7 |
64,018,928 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R4623:Fan1
|
UTSW |
7 |
64,023,301 (GRCm39) |
nonsense |
probably null |
|
|
R4918:Fan1
|
UTSW |
7 |
64,023,286 (GRCm39) |
utr 5 prime |
probably benign |
|
|
R5328:Fan1
|
UTSW |
7 |
64,004,217 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5691:Fan1
|
UTSW |
7 |
64,004,118 (GRCm39) |
splice site |
probably null |
|
|
R5902:Fan1
|
UTSW |
7 |
64,023,070 (GRCm39) |
splice site |
probably null |
|
|
R5905:Fan1
|
UTSW |
7 |
64,003,399 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6126:Fan1
|
UTSW |
7 |
64,014,318 (GRCm39) |
nonsense |
probably null |
|
|
R6195:Fan1
|
UTSW |
7 |
64,004,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6233:Fan1
|
UTSW |
7 |
64,004,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6405:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6434:Fan1
|
UTSW |
7 |
64,004,129 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6460:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6469:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6471:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6473:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6696:Fan1
|
UTSW |
7 |
63,999,826 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6708:Fan1
|
UTSW |
7 |
64,022,554 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6713:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6714:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6749:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6841:Fan1
|
UTSW |
7 |
64,014,377 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6858:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6859:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6860:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6925:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6927:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6936:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6938:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6939:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7040:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7120:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7290:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7292:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7459:Fan1
|
UTSW |
7 |
63,998,714 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7460:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7464:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7465:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7465:Fan1
|
UTSW |
7 |
64,003,386 (GRCm39) |
missense |
probably benign |
0.30 |
|
R7608:Fan1
|
UTSW |
7 |
64,003,979 (GRCm39) |
splice site |
probably null |
|
|
R7624:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7629:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7682:Fan1
|
UTSW |
7 |
64,022,512 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7731:Fan1
|
UTSW |
7 |
64,022,444 (GRCm39) |
missense |
probably benign |
0.17 |
|
R7863:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8054:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8055:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8057:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8101:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8241:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8262:Fan1
|
UTSW |
7 |
64,023,054 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8274:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8275:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8276:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8285:Fan1
|
UTSW |
7 |
64,016,348 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8318:Fan1
|
UTSW |
7 |
63,999,803 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8402:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8466:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8468:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8799:Fan1
|
UTSW |
7 |
64,016,406 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8821:Fan1
|
UTSW |
7 |
64,004,249 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9030:Fan1
|
UTSW |
7 |
64,022,761 (GRCm39) |
missense |
probably benign |
0.14 |
|
R9181:Fan1
|
UTSW |
7 |
64,016,400 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9525:Fan1
|
UTSW |
7 |
64,022,007 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9564:Fan1
|
UTSW |
7 |
63,999,240 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R9565:Fan1
|
UTSW |
7 |
63,999,240 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R9796:Fan1
|
UTSW |
7 |
64,022,278 (GRCm39) |
missense |
probably benign |
0.09 |
|
X0025:Fan1
|
UTSW |
7 |
64,022,583 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
| Predicted Primers |
PCR Primer
(F):5'- CCTTCTCCTGCTCATCGAAGAG -3'
(R):5'- GTAACACGAAATCCTCTCCGG -3'
Sequencing Primer
(F):5'- TCATCGAAGAGCTTCATGTCC -3'
(R):5'- TCTCCGGGAGACACTCTTGTAAAG -3'
|
| Posted On |
2020-01-23 |
Incidental Mutation