|Institutional Source||Beutler Lab|
|Gene Name||solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10|
|Is this an essential gene?||Non essential (E-score: 0.000)|
|Stock #||R7618 (G1)|
|Chromosomal Location||120491840-120499187 bp(+) (GRCm38)|
|Type of Mutation||splice site|
|DNA Base Change (assembly)||G to A at 120496971 bp (GRCm38)|
|Amino Acid Change|
|Ref Sequence||ENSEMBL: ENSMUSP00000026899 (fasta)|
|Gene Model||predicted gene model for transcript(s): [ENSMUST00000026899]|
|Coding Region Coverage||
|Validation Efficiency||98% (51/52)|
|MGI Phenotype||FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of a family of proteins that translocate small metabolites across the mitochondrial membrane. The encoded protein exchanges dicarboxylates, such as malate and succinate, for phosphate, sulfate, and other small molecules, thereby providing substrates for metabolic processes including the Krebs cycle and fatty acid synthesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]|
|Allele List at MGI|
|Other mutations in this stock||
|Other mutations in Slc25a10||
(F):5'- ATCGTCTACAGGGATTACAGCAC -3'
(R):5'- ACGGGCTCCTTGAATCAAGC -3'
(F):5'- CCGAGCACTGGAAACCATGG -3'
(R):5'- GGCTCCTTGAATCAAGCTCCAC -3'