|Institutional Source||Beutler Lab|
|Gene Name||ankyrin repeat and SOCS box-containing 13|
|Is this an essential gene?||Probably non essential (E-score: 0.084)|
|Stock #||R7735 (G1)|
|Chromosomal Location||3634032-3653822 bp(+) (GRCm38)|
|Type of Mutation||splice site (5 bp from exon)|
|DNA Base Change (assembly)||G to A at 3634180 bp|
|Amino Acid Change|
|Ref Sequence||ENSEMBL: ENSMUSP00000046476 (fasta)|
|Gene Model||predicted gene model for transcript(s): [ENSMUST00000042288]|
|Predicted Effect||probably null
|Coding Region Coverage||
|Validation Efficiency||100% (58/58)|
|MGI Phenotype||FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants, both protein-coding and not protein-coding, have been described for this gene. [provided by RefSeq, Nov 2010]|
|Allele List at MGI|
|Other mutations in this stock||
|Other mutations in Asb13||
(F):5'- TGGCCATGGTAGCAATCAGG -3'
(R):5'- GCGACAGACATTAAACGTCG -3'
(F):5'- ATGGTAGCAATCAGGCCCCG -3'
(R):5'- TCTGAGATGACCAGGATCGTC -3'