|Institutional Source||Beutler Lab|
|Gene Name||solute carrier family 6 (neurotransmitter transporter), member 15|
|Essential gene?||Non essential (E-score: 0.000)|
|Stock #||R7660 (G1)|
|Chromosomal Location||103367783-103419377 bp(+) (GRCm38)|
|Type of Mutation||splice site|
|DNA Base Change (assembly)||T to A at 103393380 bp (GRCm38)|
|Amino Acid Change|
|Ref Sequence||ENSEMBL: ENSMUSP00000151517 (fasta)|
|Gene Model||predicted gene model for transcript(s): [ENSMUST00000074204] [ENSMUST00000179636] [ENSMUST00000217905]|
|Coding Region Coverage||
|Validation Efficiency||100% (70/70)|
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the solute carrier family 6 protein family which transports neutral amino acids. The encoded protein is thought to play a role in neuronal amino acid transport (PMID: 16185194) and may be associated with major depression (PMID: 21521612). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]
PHENOTYPE: Mice homozygous for a null allele exhibit decreased synaptosome transport activities but exhibit no behavioral abnormalities. [provided by MGI curators]
|Allele List at MGI|
|Other mutations in this stock||
|Other mutations in Slc6a15||
(F):5'- TTCCTAGAGCAGTCTAATACAGGATTC -3'
(R):5'- CCCGGGTAAGAGCAAATGTC -3'
(F):5'- AGGTCAGTTATGTTTTCTTCA -3'
(R):5'- GGAAAGAAACTTACTACACAGCTTG -3'