Mutagenetix > Incidental Mutation

Incidental Mutation 'R8079:Baz2b'

629179

Institutional Source

Beutler Lab

Gene Symbol

Baz2b

Ensembl Gene

ENSMUSG00000026987

Gene Name

bromodomain adjacent to zinc finger domain, 2B

Synonyms

D2Ertd794e, 5830435C13Rik

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.321) question?

Stock #

R8079 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

59899363-60209839 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 59900768 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Arginine to Tryptophan at position 2085 (R2085W)

Ref Sequence

ENSEMBL: ENSMUSP00000088443 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000090925] [ENSMUST00000112550]

AlphaFold

A2AUY4

Predicted Effect

probably damaging
Transcript: ENSMUST00000090925
AA Change: R2085W

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000088443
Gene: ENSMUSG00000026987
AA Change: R2085W

Domain	Start	End	E-Value	Type
low complexity region	7	46	N/A	INTRINSIC
low complexity region	82	97	N/A	INTRINSIC
low complexity region	147	162	N/A	INTRINSIC
low complexity region	193	244	N/A	INTRINSIC
low complexity region	291	308	N/A	INTRINSIC
low complexity region	366	385	N/A	INTRINSIC
low complexity region	528	540	N/A	INTRINSIC
low complexity region	554	614	N/A	INTRINSIC
low complexity region	628	637	N/A	INTRINSIC
low complexity region	671	685	N/A	INTRINSIC
Pfam:MBD	690	742	1e-12	PFAM
low complexity region	759	774	N/A	INTRINSIC
coiled coil region	814	975	N/A	INTRINSIC
DDT	1004	1069	1.19e-20	SMART
low complexity region	1199	1212	N/A	INTRINSIC
low complexity region	1213	1247	N/A	INTRINSIC
coiled coil region	1251	1286	N/A	INTRINSIC
low complexity region	1320	1337	N/A	INTRINSIC
low complexity region	1503	1524	N/A	INTRINSIC
low complexity region	1569	1582	N/A	INTRINSIC
low complexity region	1585	1605	N/A	INTRINSIC
Blast:BROMO	1802	1843	7e-18	BLAST
PHD	1888	1934	1.71e-12	SMART
low complexity region	1942	1964	N/A	INTRINSIC
low complexity region	1968	1980	N/A	INTRINSIC
BROMO	2013	2121	3.85e-41	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000112550
AA Change: R2085W

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000108169
Gene: ENSMUSG00000026987
AA Change: R2085W

Domain	Start	End	E-Value	Type
low complexity region	7	46	N/A	INTRINSIC
low complexity region	82	97	N/A	INTRINSIC
low complexity region	147	162	N/A	INTRINSIC
low complexity region	193	244	N/A	INTRINSIC
low complexity region	291	308	N/A	INTRINSIC
low complexity region	366	385	N/A	INTRINSIC
low complexity region	528	540	N/A	INTRINSIC
low complexity region	554	614	N/A	INTRINSIC
low complexity region	628	637	N/A	INTRINSIC
low complexity region	671	685	N/A	INTRINSIC
Pfam:MBD	690	741	3.4e-13	PFAM
low complexity region	759	774	N/A	INTRINSIC
coiled coil region	814	975	N/A	INTRINSIC
DDT	1004	1069	1.19e-20	SMART
low complexity region	1199	1212	N/A	INTRINSIC
low complexity region	1213	1247	N/A	INTRINSIC
coiled coil region	1251	1286	N/A	INTRINSIC
low complexity region	1320	1337	N/A	INTRINSIC
low complexity region	1503	1524	N/A	INTRINSIC
low complexity region	1569	1582	N/A	INTRINSIC
low complexity region	1585	1605	N/A	INTRINSIC
Pfam:WHIM3	1638	1676	5.1e-14	PFAM
Blast:BROMO	1802	1843	7e-18	BLAST
PHD	1888	1934	1.71e-12	SMART
low complexity region	1942	1964	N/A	INTRINSIC
low complexity region	1968	1980	N/A	INTRINSIC
BROMO	2013	2121	3.85e-41	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000130637

SMART Domains

Protein: ENSMUSP00000119690
Gene: ENSMUSG00000026987

Domain	Start	End	E-Value	Type
Pfam:WHIM3	2	37	1.8e-13	PFAM
low complexity region	162	173	N/A	INTRINSIC
PHD	214	253	2.05e-1	SMART

Coding Region Coverage

1x: 99.9%
3x: 99.7%
10x: 99.0%
20x: 96.5%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene belongs to the bromodomain gene family. Members of this gene family encode proteins that are integral components of chromatin remodeling complexes. The encoded protein showed strong preference for the activating H3K14Ac mark in a histone peptide screen, suggesting a potential role in transcriptional activation. This gene may be associated with susceptibility to sudden cardiac death (SCD). [provided by RefSeq, Aug 2016]

Allele List at MGI

Other mutations in this stock

Total: 86 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abcb9	A	G	5: 124,083,123 (GRCm38)	I255T	possibly damaging	Het
Ablim1	A	T	19: 57,182,224 (GRCm38)		probably null	Het
Akap10	G	A	11: 61,930,054 (GRCm38)	P8L	possibly damaging	Het
Ankle2	C	T	5: 110,231,316 (GRCm38)	A27V	probably damaging	Het
Anxa8	A	G	14: 34,094,812 (GRCm38)	T246A	probably benign	Het
Arhgap5	A	G	12: 52,567,205 (GRCm38)	N1460S	probably benign	Het
Arid5b	T	G	10: 68,098,356 (GRCm38)	D572A	possibly damaging	Het
Atrn	T	A	2: 131,013,641 (GRCm38)	L1278Q	probably null	Het
AU040320	G	T	4: 126,832,160 (GRCm38)	K454N	possibly damaging	Het
Bbx	A	T	16: 50,210,458 (GRCm38)	N649K	probably damaging	Het
BC034090	G	A	1: 155,225,286 (GRCm38)	P411S	probably damaging	Het
Calcoco2	A	T	11: 96,107,537 (GRCm38)	F20Y	probably damaging	Het
Carmil2	A	G	8: 105,686,761 (GRCm38)	R50G	probably damaging	Het
Catspere2	A	G	1: 178,046,959 (GRCm38)	T131A	probably benign	Het
Cdcp1	C	A	9: 123,173,790 (GRCm38)	V739L	probably damaging	Het
Chit1	A	G	1: 134,144,027 (GRCm38)	T92A	possibly damaging	Het
Clstn3	A	G	6: 124,459,804 (GRCm38)	I185T	probably damaging	Het
Dctpp1	C	A	7: 127,259,389 (GRCm38)	V61L	probably damaging	Het
Dip2a	T	C	10: 76,287,321 (GRCm38)	T760A	probably benign	Het
Dock10	C	T	1: 80,578,704 (GRCm38)	V552I	probably benign	Het
Dpp8	A	G	9: 65,043,735 (GRCm38)	E151G	probably damaging	Het
Dvl2	G	C	11: 70,007,518 (GRCm38)	R367P	possibly damaging	Het
Fem1b	A	T	9: 62,796,361 (GRCm38)	I539N	probably damaging	Het
Frat2	A	T	19: 41,847,838 (GRCm38)	L25H	probably damaging	Het
Garnl3	A	T	2: 33,018,499 (GRCm38)		probably null	Het
Gh	T	C	11: 106,301,427 (GRCm38)	H47R	possibly damaging	Het
Glmp	T	C	3: 88,325,738 (GRCm38)	V61A	probably damaging	Het
Gm9925	T	C	18: 74,065,487 (GRCm38)	V129A	unknown	Het
H2-M9	T	A	17: 36,642,133 (GRCm38)	E94V	probably benign	Het
Hira	A	T	16: 18,925,757 (GRCm38)	Q408L	probably benign	Het
Hook3	A	G	8: 26,088,058 (GRCm38)		probably null	Het
Ifi206	G	A	1: 173,481,158 (GRCm38)	P424L		Het
Impdh2	T	C	9: 108,563,325 (GRCm38)	V270A	probably benign	Het
Klhl14	A	G	18: 21,651,965 (GRCm38)	I135T	probably benign	Het
Klra10	C	A	6: 130,275,775 (GRCm38)	V179L	probably benign	Het
Kmt2c	T	C	5: 25,302,732 (GRCm38)	S3236G	probably damaging	Het
Krt76	G	T	15: 101,888,390 (GRCm38)	A358D	possibly damaging	Het
Lacc1	C	A	14: 77,029,552 (GRCm38)	G424C	probably damaging	Het
Limch1	A	G	5: 67,046,753 (GRCm38)	I878V	possibly damaging	Het
Lipi	C	T	16: 75,565,530 (GRCm38)		probably null	Het
Lrrc17	C	T	5: 21,561,071 (GRCm38)	R184W	probably damaging	Het
Mllt10	A	G	2: 18,123,756 (GRCm38)	N183D	probably damaging	Het
Mterf2	C	T	10: 85,120,163 (GRCm38)	G199D	probably damaging	Het
Mucl3	T	C	17: 35,638,192 (GRCm38)	T172A	unknown	Het
Nat8f4	A	T	6: 85,900,994 (GRCm38)	S182R	probably benign	Het
Ndrg3	C	A	2: 156,937,532 (GRCm38)	E238*	probably null	Het
Nop14	A	T	5: 34,654,461 (GRCm38)	L194H	probably damaging	Het
Obscn	T	C	11: 59,081,905 (GRCm38)	E2105G	possibly damaging	Het
Or5b104	A	C	19: 13,095,284 (GRCm38)	Y121*	probably null	Het
Or5g9	A	T	2: 85,722,043 (GRCm38)	T213S	probably benign	Het
Or7g17	A	T	9: 18,857,429 (GRCm38)	Y259F	possibly damaging	Het
Or8k32	T	A	2: 86,538,381 (GRCm38)	H176L	possibly damaging	Het
Pbx3	C	T	2: 34,178,228 (GRCm38)	A320T	probably benign	Het
Pcdhac2	A	T	18: 37,146,144 (GRCm38)	S726C	probably damaging	Het
Pcdhgb2	A	G	18: 37,690,763 (GRCm38)	D269G	probably damaging	Het
Pcgf6	A	T	19: 47,045,832 (GRCm38)	S257T	probably damaging	Het
Pclo	A	T	5: 14,540,458 (GRCm38)	H924L	unknown	Het
Per3	T	A	4: 151,042,678 (GRCm38)	T129S	possibly damaging	Het
Pi4ka	A	T	16: 17,303,060 (GRCm38)	M1270K		Het
Plec	G	A	15: 76,179,550 (GRCm38)	Q2277*	probably null	Het
Pnma1	T	A	12: 84,147,335 (GRCm38)	K198M	probably damaging	Het
Prc1	T	A	7: 80,304,767 (GRCm38)	F196L	possibly damaging	Het
Prkcz	T	C	4: 155,357,505 (GRCm38)	T57A	probably damaging	Het
Repin1	G	T	6: 48,597,345 (GRCm38)	E403*	probably null	Het
Robo4	A	G	9: 37,402,635 (GRCm38)	M61V	possibly damaging	Het
Rps12	C	T	10: 23,785,677 (GRCm38)	V79I	probably benign	Het
Rsph3a	A	G	17: 7,979,188 (GRCm38)	K466E	probably benign	Het
Scly	A	T	1: 91,308,367 (GRCm38)	I168F	probably damaging	Het
Setd1a	T	A	7: 127,785,053 (GRCm38)	F359I	unknown	Het
Sh3tc1	A	G	5: 35,706,857 (GRCm38)	L662P	possibly damaging	Het
Slc12a5	T	C	2: 164,992,452 (GRCm38)	W798R	probably damaging	Het
Slc16a6	C	T	11: 109,473,455 (GRCm38)	R13Q	unknown	Het
Slco1a8	T	G	6: 141,987,734 (GRCm38)	M462L	probably benign	Het
Smarcad1	A	G	6: 65,052,782 (GRCm38)	D118G	possibly damaging	Het
Sos2	T	C	12: 69,607,215 (GRCm38)	T788A	probably damaging	Het
Syvn1	A	G	19: 6,048,366 (GRCm38)	E75G	probably null	Het
Thpo	T	C	16: 20,726,394 (GRCm38)	E103G	probably benign	Het
Trav7d-3	A	T	14: 52,744,736 (GRCm38)	E78V	possibly damaging	Het
Uap1	A	G	1: 170,158,763 (GRCm38)	S217P	probably damaging	Het
Unc45a	T	G	7: 80,331,562 (GRCm38)	R497S	probably damaging	Het
Upf1	A	G	8: 70,338,884 (GRCm38)		probably null	Het
Usp47	A	T	7: 112,046,970 (GRCm38)	K28M	probably damaging	Het
Wdr72	A	C	9: 74,218,772 (GRCm38)	T1062P	probably damaging	Het
Wnt7b	A	T	15: 85,537,445 (GRCm38)	C339S	probably damaging	Het
Zfp954	G	T	7: 7,115,471 (GRCm38)	T358K	probably benign	Het
Zmynd15	G	T	11: 70,459,452 (GRCm38)		probably benign	Het

Other mutations in Baz2b

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00430:Baz2b	APN	2	59,912,795 (GRCm38)	missense	probably benign	0.02
IGL00476:Baz2b	APN	2	59,913,739 (GRCm38)	missense	probably benign	0.06
IGL00489:Baz2b	APN	2	59,957,675 (GRCm38)	nonsense	probably null
IGL00514:Baz2b	APN	2	59,962,477 (GRCm38)	missense	probably benign	0.11
IGL00678:Baz2b	APN	2	60,006,183 (GRCm38)	missense	unknown
IGL01348:Baz2b	APN	2	59,933,687 (GRCm38)	missense	possibly damaging	0.95
IGL01354:Baz2b	APN	2	59,968,889 (GRCm38)	missense	probably benign	0.18
IGL01924:Baz2b	APN	2	59,935,271 (GRCm38)	missense	probably damaging	1.00
IGL02125:Baz2b	APN	2	59,968,640 (GRCm38)	missense	probably benign	0.12
IGL02314:Baz2b	APN	2	59,962,227 (GRCm38)	missense	probably benign
IGL02370:Baz2b	APN	2	59,923,589 (GRCm38)	missense	possibly damaging	0.77
IGL02473:Baz2b	APN	2	59,960,063 (GRCm38)	missense	probably benign	0.40
IGL02499:Baz2b	APN	2	59,901,496 (GRCm38)	missense	possibly damaging	0.60
IGL02609:Baz2b	APN	2	59,917,369 (GRCm38)	missense	possibly damaging	0.77
IGL02705:Baz2b	APN	2	59,948,260 (GRCm38)	missense	possibly damaging	0.92
IGL02711:Baz2b	APN	2	59,917,505 (GRCm38)	unclassified	probably benign
IGL02716:Baz2b	APN	2	59,962,524 (GRCm38)	missense	possibly damaging	0.53
IGL02724:Baz2b	APN	2	59,977,374 (GRCm38)	missense	possibly damaging	0.70
IGL02750:Baz2b	APN	2	59,968,658 (GRCm38)	missense	possibly damaging	0.73
IGL02869:Baz2b	APN	2	59,977,528 (GRCm38)	missense	probably benign	0.00
IGL02886:Baz2b	APN	2	59,957,743 (GRCm38)	splice site	probably null
IGL02892:Baz2b	APN	2	59,900,736 (GRCm38)	missense	probably damaging	1.00
IGL03132:Baz2b	APN	2	59,907,753 (GRCm38)	splice site	probably benign
IGL03183:Baz2b	APN	2	59,903,296 (GRCm38)	missense	probably benign	0.10
IGL03197:Baz2b	APN	2	59,901,554 (GRCm38)	missense	possibly damaging	0.74
R0054:Baz2b	UTSW	2	59,932,166 (GRCm38)	missense	probably damaging	1.00
R0054:Baz2b	UTSW	2	59,932,166 (GRCm38)	missense	probably damaging	1.00
R0122:Baz2b	UTSW	2	59,913,619 (GRCm38)	splice site	probably null
R0136:Baz2b	UTSW	2	59,901,954 (GRCm38)	missense	probably benign	0.22
R0144:Baz2b	UTSW	2	59,907,495 (GRCm38)	missense	probably damaging	0.98
R0403:Baz2b	UTSW	2	59,969,377 (GRCm38)	missense	possibly damaging	0.70
R0498:Baz2b	UTSW	2	59,901,996 (GRCm38)	unclassified	probably benign
R0528:Baz2b	UTSW	2	59,936,739 (GRCm38)	missense	probably damaging	1.00
R1025:Baz2b	UTSW	2	59,962,482 (GRCm38)	missense	probably benign	0.06
R1470:Baz2b	UTSW	2	59,978,546 (GRCm38)	missense	possibly damaging	0.53
R1470:Baz2b	UTSW	2	59,978,546 (GRCm38)	missense	possibly damaging	0.53
R1510:Baz2b	UTSW	2	59,922,209 (GRCm38)	missense	probably damaging	1.00
R1511:Baz2b	UTSW	2	59,962,024 (GRCm38)	missense	probably benign	0.12
R1514:Baz2b	UTSW	2	59,962,326 (GRCm38)	missense	probably benign	0.13
R1519:Baz2b	UTSW	2	59,948,254 (GRCm38)	missense	possibly damaging	0.50
R1523:Baz2b	UTSW	2	59,968,637 (GRCm38)	missense	possibly damaging	0.47
R1630:Baz2b	UTSW	2	60,006,130 (GRCm38)	missense	unknown
R1641:Baz2b	UTSW	2	59,912,890 (GRCm38)	missense	probably damaging	0.99
R1674:Baz2b	UTSW	2	59,912,992 (GRCm38)	missense	possibly damaging	0.53
R1778:Baz2b	UTSW	2	60,006,136 (GRCm38)	missense	unknown
R1826:Baz2b	UTSW	2	59,968,733 (GRCm38)	missense	probably benign	0.12
R1835:Baz2b	UTSW	2	59,901,819 (GRCm38)	missense	probably benign	0.02
R1954:Baz2b	UTSW	2	59,968,743 (GRCm38)	missense	probably benign	0.12
R1981:Baz2b	UTSW	2	59,923,680 (GRCm38)	missense	possibly damaging	0.95
R2029:Baz2b	UTSW	2	59,912,723 (GRCm38)	unclassified	probably benign
R2567:Baz2b	UTSW	2	59,913,911 (GRCm38)	missense	possibly damaging	0.82
R2842:Baz2b	UTSW	2	59,913,004 (GRCm38)	missense	probably benign	0.27
R2848:Baz2b	UTSW	2	59,924,666 (GRCm38)	missense	possibly damaging	0.64
R3809:Baz2b	UTSW	2	59,968,896 (GRCm38)	missense	probably benign	0.12
R3935:Baz2b	UTSW	2	59,912,761 (GRCm38)	missense	possibly damaging	0.81
R3936:Baz2b	UTSW	2	59,912,761 (GRCm38)	missense	possibly damaging	0.81
R4072:Baz2b	UTSW	2	59,912,573 (GRCm38)	splice site	probably null
R4182:Baz2b	UTSW	2	60,098,457 (GRCm38)	intron	probably benign
R4255:Baz2b	UTSW	2	59,920,572 (GRCm38)	unclassified	probably benign
R4359:Baz2b	UTSW	2	59,901,613 (GRCm38)	missense	possibly damaging	0.87
R4716:Baz2b	UTSW	2	59,969,255 (GRCm38)	missense	probably benign	0.06
R4743:Baz2b	UTSW	2	59,913,911 (GRCm38)	missense	probably benign	0.01
R4772:Baz2b	UTSW	2	59,958,451 (GRCm38)	missense	probably damaging	0.96
R4858:Baz2b	UTSW	2	59,907,743 (GRCm38)	missense	probably benign
R4868:Baz2b	UTSW	2	59,924,882 (GRCm38)	missense	possibly damaging	0.65
R4872:Baz2b	UTSW	2	59,942,759 (GRCm38)	splice site	probably null
R4889:Baz2b	UTSW	2	59,936,726 (GRCm38)	missense	probably damaging	1.00
R4890:Baz2b	UTSW	2	59,926,039 (GRCm38)	missense	probably damaging	0.99
R4914:Baz2b	UTSW	2	59,914,043 (GRCm38)	missense	possibly damaging	0.70
R4915:Baz2b	UTSW	2	59,914,043 (GRCm38)	missense	possibly damaging	0.70
R4918:Baz2b	UTSW	2	59,914,043 (GRCm38)	missense	possibly damaging	0.70
R5027:Baz2b	UTSW	2	60,098,644 (GRCm38)	intron	probably benign
R5031:Baz2b	UTSW	2	59,912,807 (GRCm38)	missense	probably benign	0.00
R5082:Baz2b	UTSW	2	59,901,491 (GRCm38)	nonsense	probably null
R5133:Baz2b	UTSW	2	59,962,024 (GRCm38)	missense	probably benign	0.12
R5276:Baz2b	UTSW	2	59,962,614 (GRCm38)	missense	probably benign	0.40
R5279:Baz2b	UTSW	2	59,932,152 (GRCm38)	missense	probably damaging	1.00
R5294:Baz2b	UTSW	2	59,978,602 (GRCm38)	missense	probably benign	0.11
R5447:Baz2b	UTSW	2	59,913,988 (GRCm38)	missense	probably damaging	0.99
R5903:Baz2b	UTSW	2	59,959,889 (GRCm38)	missense	probably damaging	0.99
R5910:Baz2b	UTSW	2	59,977,426 (GRCm38)	missense	possibly damaging	0.88
R6140:Baz2b	UTSW	2	59,912,527 (GRCm38)	missense	probably damaging	0.99
R6195:Baz2b	UTSW	2	59,907,511 (GRCm38)	missense	possibly damaging	0.89
R6199:Baz2b	UTSW	2	59,978,675 (GRCm38)	missense	probably benign	0.00
R6208:Baz2b	UTSW	2	59,924,806 (GRCm38)	missense	probably damaging	1.00
R6233:Baz2b	UTSW	2	59,907,511 (GRCm38)	missense	possibly damaging	0.89
R6276:Baz2b	UTSW	2	59,948,223 (GRCm38)	missense	probably damaging	1.00
R6324:Baz2b	UTSW	2	59,906,948 (GRCm38)	missense	probably damaging	1.00
R6490:Baz2b	UTSW	2	59,901,729 (GRCm38)	missense	probably damaging	1.00
R6578:Baz2b	UTSW	2	59,969,279 (GRCm38)	missense	possibly damaging	0.47
R6720:Baz2b	UTSW	2	59,924,890 (GRCm38)	missense	probably damaging	1.00
R6760:Baz2b	UTSW	2	59,962,432 (GRCm38)	missense	probably benign	0.40
R6836:Baz2b	UTSW	2	59,917,425 (GRCm38)	missense	probably damaging	1.00
R6859:Baz2b	UTSW	2	59,901,530 (GRCm38)	missense	probably benign	0.01
R6880:Baz2b	UTSW	2	59,912,939 (GRCm38)	missense	probably damaging	0.99
R6916:Baz2b	UTSW	2	59,968,776 (GRCm38)	missense	probably benign
R6978:Baz2b	UTSW	2	59,907,715 (GRCm38)	missense	possibly damaging	0.84
R7037:Baz2b	UTSW	2	59,933,670 (GRCm38)	critical splice donor site	probably null
R7112:Baz2b	UTSW	2	59,962,184 (GRCm38)	missense	possibly damaging	0.53
R7117:Baz2b	UTSW	2	59,912,497 (GRCm38)	missense
R7198:Baz2b	UTSW	2	59,962,206 (GRCm38)	missense	probably benign	0.00
R7270:Baz2b	UTSW	2	59,962,492 (GRCm38)	missense	possibly damaging	0.96
R7282:Baz2b	UTSW	2	59,920,437 (GRCm38)	missense	probably benign	0.17
R7464:Baz2b	UTSW	2	59,977,448 (GRCm38)	missense	possibly damaging	0.53
R7609:Baz2b	UTSW	2	59,962,473 (GRCm38)	missense	probably benign	0.40
R7703:Baz2b	UTSW	2	59,917,425 (GRCm38)	missense	probably damaging	1.00
R7850:Baz2b	UTSW	2	59,936,716 (GRCm38)	missense	probably damaging	0.98
R7851:Baz2b	UTSW	2	59,936,716 (GRCm38)	missense	probably damaging	0.98
R7988:Baz2b	UTSW	2	59,962,141 (GRCm38)	missense	possibly damaging	0.53
R8084:Baz2b	UTSW	2	59,962,236 (GRCm38)	missense	probably benign
R8343:Baz2b	UTSW	2	59,901,514 (GRCm38)	missense	probably damaging	1.00
R8348:Baz2b	UTSW	2	59,911,793 (GRCm38)	missense
R8438:Baz2b	UTSW	2	59,917,484 (GRCm38)	nonsense	probably null
R8448:Baz2b	UTSW	2	59,911,793 (GRCm38)	missense
R8511:Baz2b	UTSW	2	59,901,814 (GRCm38)	missense	probably benign
R8893:Baz2b	UTSW	2	59,924,805 (GRCm38)	missense	probably damaging	0.96
R8947:Baz2b	UTSW	2	59,948,239 (GRCm38)	missense	probably benign	0.06
R8998:Baz2b	UTSW	2	59,969,264 (GRCm38)	missense	probably benign	0.02
R9241:Baz2b	UTSW	2	59,913,649 (GRCm38)	missense	probably benign	0.01
R9245:Baz2b	UTSW	2	59,912,987 (GRCm38)	missense	probably benign
R9577:Baz2b	UTSW	2	59,978,687 (GRCm38)	missense	probably benign	0.06
R9581:Baz2b	UTSW	2	59,968,956 (GRCm38)	missense	probably benign
R9601:Baz2b	UTSW	2	59,901,503 (GRCm38)	missense	possibly damaging	0.66
R9613:Baz2b	UTSW	2	59,901,480 (GRCm38)	missense	probably benign	0.09
R9639:Baz2b	UTSW	2	59,901,484 (GRCm38)	missense	probably benign	0.01
X0011:Baz2b	UTSW	2	59,977,361 (GRCm38)	missense	possibly damaging	0.53
X0053:Baz2b	UTSW	2	59,900,675 (GRCm38)	missense	probably damaging	1.00
X0064:Baz2b	UTSW	2	59,969,282 (GRCm38)	missense	probably benign
Z1088:Baz2b	UTSW	2	59,960,015 (GRCm38)	missense	probably damaging	1.00
Z1177:Baz2b	UTSW	2	59,977,520 (GRCm38)	missense	probably benign	0.01
Z1188:Baz2b	UTSW	2	59,977,405 (GRCm38)	missense	probably benign

Predicted Primers

PCR Primer
(F):5'- GAATGCAGTTCACACCGCTG -3'
(R):5'- GAGCCTAATGAATGTAATCGGGTG -3'

Sequencing Primer
(F):5'- AGTTCACACCGCTGGTCTTG -3'
(R):5'- GCTTCAGCAGGAGGAGTTATG -3'

Posted On

2020-06-30