Incidental Mutation 'R8087:Arhgap32'
| ID |
629720 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Arhgap32
|
| Ensembl Gene |
ENSMUSG00000041444 |
| Gene Name |
Rho GTPase activating protein 32 |
| Synonyms |
p200RhoGAP, Grit, PX-RICS, GC-GAP, 3426406O18Rik |
| MMRRC Submission |
067520-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R8087 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
9 |
| Chromosomal Location |
32027432-32179742 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 32168324 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Serine
at position 769
(N769S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000138145
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000168954]
[ENSMUST00000174641]
[ENSMUST00000182802]
|
| AlphaFold |
Q811P8 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000168954
AA Change: N769S
PolyPhen 2
Score 0.002 (Sensitivity: 0.99; Specificity: 0.30)
|
| SMART Domains |
Protein: ENSMUSP00000128448
Gene: ENSMUSG00000041444
AA Change: N769S
| Domain | Start | End | E-Value | Type |
|---|
|
RhoGAP
|
34 |
215 |
9.6e-60 |
SMART |
|
Blast:RhoGAP
|
232 |
298 |
7e-31 |
BLAST |
|
low complexity region
|
518 |
533 |
N/A |
INTRINSIC |
|
low complexity region
|
669 |
689 |
N/A |
INTRINSIC |
|
low complexity region
|
696 |
710 |
N/A |
INTRINSIC |
|
low complexity region
|
913 |
926 |
N/A |
INTRINSIC |
|
low complexity region
|
960 |
974 |
N/A |
INTRINSIC |
|
low complexity region
|
997 |
1008 |
N/A |
INTRINSIC |
|
low complexity region
|
1076 |
1093 |
N/A |
INTRINSIC |
|
low complexity region
|
1304 |
1317 |
N/A |
INTRINSIC |
|
low complexity region
|
1691 |
1700 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000174641
AA Change: N1118S
PolyPhen 2
Score 0.002 (Sensitivity: 0.99; Specificity: 0.30)
|
| SMART Domains |
Protein: ENSMUSP00000133898
Gene: ENSMUSG00000041444
AA Change: N1118S
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:PX
|
132 |
226 |
5.6e-7 |
PFAM |
|
SH3
|
262 |
320 |
7.4e-11 |
SMART |
|
RhoGAP
|
383 |
564 |
9.6e-60 |
SMART |
|
Blast:RhoGAP
|
581 |
647 |
9e-31 |
BLAST |
|
low complexity region
|
867 |
882 |
N/A |
INTRINSIC |
|
low complexity region
|
1018 |
1038 |
N/A |
INTRINSIC |
|
low complexity region
|
1045 |
1059 |
N/A |
INTRINSIC |
|
low complexity region
|
1262 |
1275 |
N/A |
INTRINSIC |
|
low complexity region
|
1309 |
1323 |
N/A |
INTRINSIC |
|
low complexity region
|
1346 |
1357 |
N/A |
INTRINSIC |
|
low complexity region
|
1425 |
1442 |
N/A |
INTRINSIC |
|
low complexity region
|
1653 |
1666 |
N/A |
INTRINSIC |
|
low complexity region
|
2040 |
2049 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000182802
AA Change: N769S
PolyPhen 2
Score 0.002 (Sensitivity: 0.99; Specificity: 0.30)
|
| SMART Domains |
Protein: ENSMUSP00000138145
Gene: ENSMUSG00000041444
AA Change: N769S
| Domain | Start | End | E-Value | Type |
|---|
|
RhoGAP
|
34 |
215 |
9.6e-60 |
SMART |
|
Blast:RhoGAP
|
232 |
298 |
7e-31 |
BLAST |
|
low complexity region
|
518 |
533 |
N/A |
INTRINSIC |
|
low complexity region
|
669 |
689 |
N/A |
INTRINSIC |
|
low complexity region
|
696 |
710 |
N/A |
INTRINSIC |
|
low complexity region
|
913 |
926 |
N/A |
INTRINSIC |
|
low complexity region
|
960 |
974 |
N/A |
INTRINSIC |
|
low complexity region
|
997 |
1008 |
N/A |
INTRINSIC |
|
low complexity region
|
1076 |
1093 |
N/A |
INTRINSIC |
|
low complexity region
|
1304 |
1317 |
N/A |
INTRINSIC |
|
low complexity region
|
1691 |
1700 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.7%
- 10x: 97.7%
- 20x: 83.0%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] RICS is a neuron-associated GTPase-activating protein that may regulate dendritic spine morphology and strength by modulating Rho GTPase (see RHOA; MIM 165390) activity (Okabe et al., 2003 [PubMed 12531901]).[supplied by OMIM, Mar 2008]
PHENOTYPE: Mice homozygous for a null mutation are fertile but display abnormal neurite growth. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 77 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930451I11Rik |
A |
G |
7: 126,430,052 (GRCm39) |
V73A |
possibly damaging |
Het |
| Abcg1 |
T |
C |
17: 31,283,459 (GRCm39) |
L48P |
probably benign |
Het |
| Ablim1 |
A |
G |
19: 57,170,688 (GRCm39) |
W18R |
|
Het |
| Acss1 |
A |
G |
2: 150,484,668 (GRCm39) |
F192L |
probably damaging |
Het |
| BC004004 |
T |
A |
17: 29,513,064 (GRCm39) |
L163I |
probably damaging |
Het |
| Bco1 |
A |
T |
8: 117,835,501 (GRCm39) |
T151S |
possibly damaging |
Het |
| Btbd8 |
T |
A |
5: 107,632,953 (GRCm39) |
Y264N |
probably damaging |
Het |
| C1ra |
G |
A |
6: 124,490,831 (GRCm39) |
V75I |
probably damaging |
Het |
| Cadps |
A |
C |
14: 12,536,380 (GRCm38) |
W527G |
probably damaging |
Het |
| Calca |
T |
C |
7: 114,231,809 (GRCm39) |
N85D |
probably benign |
Het |
| Capn13 |
A |
G |
17: 73,623,279 (GRCm39) |
L644P |
probably damaging |
Het |
| Ccdc57 |
T |
C |
11: 120,788,705 (GRCm39) |
I381V |
probably benign |
Het |
| Ccr1 |
A |
G |
9: 123,764,371 (GRCm39) |
V53A |
probably benign |
Het |
| Cd27 |
G |
T |
6: 125,210,325 (GRCm39) |
A234D |
possibly damaging |
Het |
| Cnpy4 |
T |
A |
5: 138,188,532 (GRCm39) |
V46E |
probably damaging |
Het |
| Cspp1 |
T |
G |
1: 10,174,489 (GRCm39) |
D647E |
possibly damaging |
Het |
| Ctnnd1 |
A |
T |
2: 84,441,220 (GRCm39) |
F660I |
possibly damaging |
Het |
| Dchs1 |
A |
T |
7: 105,402,706 (GRCm39) |
S3279T |
probably benign |
Het |
| Ddx11 |
T |
A |
17: 66,456,988 (GRCm39) |
Y772N |
probably damaging |
Het |
| Dennd11 |
T |
A |
6: 40,395,526 (GRCm39) |
D194V |
possibly damaging |
Het |
| Dgkd |
T |
A |
1: 87,844,569 (GRCm39) |
V245E |
probably damaging |
Het |
| Dmgdh |
C |
T |
13: 93,840,379 (GRCm39) |
T270I |
possibly damaging |
Het |
| Elac2 |
A |
G |
11: 64,870,034 (GRCm39) |
H33R |
probably benign |
Het |
| Emilin1 |
T |
A |
5: 31,074,444 (GRCm39) |
D228E |
probably damaging |
Het |
| F2rl1 |
A |
G |
13: 95,650,507 (GRCm39) |
L125P |
probably damaging |
Het |
| Fam186a |
A |
G |
15: 99,839,725 (GRCm39) |
V2173A |
possibly damaging |
Het |
| Foxp4 |
C |
A |
17: 48,215,355 (GRCm39) |
G30C |
probably damaging |
Het |
| Fyn |
T |
A |
10: 39,405,553 (GRCm39) |
L273* |
probably null |
Het |
| Garnl3 |
G |
T |
2: 32,935,548 (GRCm39) |
D196E |
probably benign |
Het |
| Glb1 |
A |
T |
9: 114,259,483 (GRCm39) |
T220S |
probably damaging |
Het |
| Hsdl2 |
G |
T |
4: 59,592,228 (GRCm39) |
A31S |
unknown |
Het |
| Irak3 |
T |
A |
10: 120,018,440 (GRCm39) |
I103F |
probably benign |
Het |
| Khdrbs2 |
A |
T |
1: 32,454,057 (GRCm39) |
M148L |
probably benign |
Het |
| Kif2c |
A |
T |
4: 117,022,615 (GRCm39) |
S500R |
possibly damaging |
Het |
| Kmt2c |
T |
C |
5: 25,534,250 (GRCm39) |
Y1500C |
probably damaging |
Het |
| Lrp2 |
T |
C |
2: 69,278,473 (GRCm39) |
D3960G |
probably damaging |
Het |
| Map2k6 |
A |
T |
11: 110,381,002 (GRCm39) |
I39L |
probably benign |
Het |
| Muc13 |
G |
T |
16: 33,619,397 (GRCm39) |
Q48H |
unknown |
Het |
| Nlrp1b |
A |
T |
11: 71,062,897 (GRCm39) |
I721N |
probably benign |
Het |
| Ntsr1 |
A |
T |
2: 180,141,965 (GRCm39) |
|
probably benign |
Het |
| Nubp1 |
T |
C |
16: 10,238,212 (GRCm39) |
|
probably null |
Het |
| Or2h2c |
T |
C |
17: 37,422,440 (GRCm39) |
I145V |
probably benign |
Het |
| Ovol3 |
A |
C |
7: 29,933,797 (GRCm39) |
D108E |
probably damaging |
Het |
| Pcdhb4 |
C |
A |
18: 37,441,717 (GRCm39) |
N342K |
probably damaging |
Het |
| Pcgf3 |
A |
G |
5: 108,634,102 (GRCm39) |
D120G |
probably benign |
Het |
| Pde6b |
T |
C |
5: 108,536,328 (GRCm39) |
V8A |
probably benign |
Het |
| Pkhd1 |
G |
T |
1: 20,593,313 (GRCm39) |
T1600K |
probably damaging |
Het |
| Pkp3 |
A |
G |
7: 140,667,551 (GRCm39) |
I451V |
possibly damaging |
Het |
| Plce1 |
A |
G |
19: 38,724,965 (GRCm39) |
T1439A |
probably damaging |
Het |
| Prr27 |
C |
A |
5: 87,994,168 (GRCm39) |
N347K |
probably benign |
Het |
| Prss41 |
T |
C |
17: 24,056,076 (GRCm39) |
Y259C |
probably damaging |
Het |
| Rasgef1b |
T |
C |
5: 99,369,248 (GRCm39) |
I457V |
probably benign |
Het |
| Rspry1 |
G |
A |
8: 95,380,925 (GRCm39) |
V534M |
probably benign |
Het |
| Rxrb |
T |
C |
17: 34,254,763 (GRCm39) |
V306A |
probably benign |
Het |
| Sim1 |
T |
C |
10: 50,785,651 (GRCm39) |
M240T |
possibly damaging |
Het |
| Slc22a4 |
A |
T |
11: 53,886,887 (GRCm39) |
I285K |
possibly damaging |
Het |
| Slc4a2 |
GGCAGCAGCAGCAGCAGCA |
GGCAGCAGCAGCAGCA |
5: 24,643,747 (GRCm39) |
|
probably benign |
Het |
| Snx19 |
T |
C |
9: 30,375,698 (GRCm39) |
M993T |
probably benign |
Het |
| Sstr2 |
G |
A |
11: 113,515,501 (GRCm39) |
R140H |
probably damaging |
Het |
| Syne1 |
C |
T |
10: 5,283,034 (GRCm39) |
R1553Q |
probably benign |
Het |
| Tchp |
T |
C |
5: 114,857,665 (GRCm39) |
I386T |
probably damaging |
Het |
| Tmem273 |
G |
T |
14: 32,507,926 (GRCm39) |
|
probably benign |
Het |
| Traf7 |
G |
T |
17: 24,731,038 (GRCm39) |
S304R |
possibly damaging |
Het |
| Trcg1 |
C |
T |
9: 57,155,957 (GRCm39) |
L798F |
probably damaging |
Het |
| Ttc3 |
C |
T |
16: 94,243,812 (GRCm39) |
P1272L |
probably benign |
Het |
| Ttf2 |
G |
T |
3: 100,871,412 (GRCm39) |
A83E |
probably damaging |
Het |
| Uba3 |
T |
A |
6: 97,162,344 (GRCm39) |
I421F |
possibly damaging |
Het |
| Ube3b |
T |
C |
5: 114,550,550 (GRCm39) |
|
probably null |
Het |
| Ulk4 |
A |
G |
9: 121,095,317 (GRCm39) |
L112P |
probably damaging |
Het |
| Unc5a |
A |
G |
13: 55,143,985 (GRCm39) |
N150S |
probably damaging |
Het |
| Vac14 |
A |
T |
8: 111,446,532 (GRCm39) |
K760N |
probably benign |
Het |
| Vmn2r113 |
A |
T |
17: 23,177,711 (GRCm39) |
I832L |
possibly damaging |
Het |
| Vmn2r-ps158 |
A |
T |
7: 42,697,094 (GRCm39) |
Y717F |
probably benign |
Het |
| Xpot |
T |
C |
10: 121,437,232 (GRCm39) |
I830V |
probably benign |
Het |
| Zfp101 |
G |
A |
17: 33,599,977 (GRCm39) |
T593I |
probably benign |
Het |
| Zfp54 |
A |
C |
17: 21,655,260 (GRCm39) |
T585P |
probably damaging |
Het |
| Zfp663 |
T |
C |
2: 165,195,679 (GRCm39) |
D180G |
probably benign |
Het |
|
| Other mutations in Arhgap32 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01020:Arhgap32
|
APN |
9 |
32,168,657 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01317:Arhgap32
|
APN |
9 |
32,168,260 (GRCm39) |
missense |
probably benign |
0.30 |
|
IGL01614:Arhgap32
|
APN |
9 |
32,171,801 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01791:Arhgap32
|
APN |
9 |
32,158,486 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02318:Arhgap32
|
APN |
9 |
32,170,627 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02542:Arhgap32
|
APN |
9 |
32,166,944 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02568:Arhgap32
|
APN |
9 |
32,158,490 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02627:Arhgap32
|
APN |
9 |
32,157,302 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02927:Arhgap32
|
APN |
9 |
32,172,431 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL03157:Arhgap32
|
APN |
9 |
32,170,430 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03286:Arhgap32
|
APN |
9 |
32,170,816 (GRCm39) |
missense |
probably benign |
0.06 |
|
PIT4445001:Arhgap32
|
UTSW |
9 |
32,172,152 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0004:Arhgap32
|
UTSW |
9 |
32,063,294 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0335:Arhgap32
|
UTSW |
9 |
32,171,056 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0380:Arhgap32
|
UTSW |
9 |
32,157,773 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0396:Arhgap32
|
UTSW |
9 |
32,156,551 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0494:Arhgap32
|
UTSW |
9 |
32,170,199 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0508:Arhgap32
|
UTSW |
9 |
32,101,364 (GRCm39) |
splice site |
probably benign |
|
|
R0856:Arhgap32
|
UTSW |
9 |
32,171,516 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0990:Arhgap32
|
UTSW |
9 |
32,166,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1312:Arhgap32
|
UTSW |
9 |
32,166,608 (GRCm39) |
missense |
probably benign |
|
|
R1455:Arhgap32
|
UTSW |
9 |
32,171,381 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1515:Arhgap32
|
UTSW |
9 |
32,027,498 (GRCm39) |
missense |
probably benign |
|
|
R1523:Arhgap32
|
UTSW |
9 |
32,168,048 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1651:Arhgap32
|
UTSW |
9 |
32,171,096 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1743:Arhgap32
|
UTSW |
9 |
32,170,727 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1999:Arhgap32
|
UTSW |
9 |
32,027,436 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R2098:Arhgap32
|
UTSW |
9 |
32,171,207 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2150:Arhgap32
|
UTSW |
9 |
32,027,436 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R2256:Arhgap32
|
UTSW |
9 |
32,158,793 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2257:Arhgap32
|
UTSW |
9 |
32,158,793 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2989:Arhgap32
|
UTSW |
9 |
32,150,694 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R3780:Arhgap32
|
UTSW |
9 |
32,063,315 (GRCm39) |
splice site |
probably null |
|
|
R3793:Arhgap32
|
UTSW |
9 |
32,166,669 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3846:Arhgap32
|
UTSW |
9 |
32,101,320 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4086:Arhgap32
|
UTSW |
9 |
32,158,362 (GRCm39) |
unclassified |
probably benign |
|
|
R4177:Arhgap32
|
UTSW |
9 |
32,158,510 (GRCm39) |
missense |
probably null |
1.00 |
|
R4230:Arhgap32
|
UTSW |
9 |
32,168,770 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4280:Arhgap32
|
UTSW |
9 |
32,171,185 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4504:Arhgap32
|
UTSW |
9 |
32,093,135 (GRCm39) |
splice site |
probably null |
|
|
R4587:Arhgap32
|
UTSW |
9 |
32,172,241 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4612:Arhgap32
|
UTSW |
9 |
32,170,775 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4622:Arhgap32
|
UTSW |
9 |
32,150,644 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R4670:Arhgap32
|
UTSW |
9 |
32,081,441 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4784:Arhgap32
|
UTSW |
9 |
32,172,076 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4784:Arhgap32
|
UTSW |
9 |
32,040,949 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4785:Arhgap32
|
UTSW |
9 |
32,040,949 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4785:Arhgap32
|
UTSW |
9 |
32,172,076 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4906:Arhgap32
|
UTSW |
9 |
32,156,552 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5046:Arhgap32
|
UTSW |
9 |
32,168,095 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5360:Arhgap32
|
UTSW |
9 |
32,170,967 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5382:Arhgap32
|
UTSW |
9 |
32,063,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5445:Arhgap32
|
UTSW |
9 |
32,159,678 (GRCm39) |
missense |
probably benign |
0.19 |
|
R5637:Arhgap32
|
UTSW |
9 |
32,158,502 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5659:Arhgap32
|
UTSW |
9 |
32,093,256 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5801:Arhgap32
|
UTSW |
9 |
32,167,084 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6002:Arhgap32
|
UTSW |
9 |
32,168,275 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6109:Arhgap32
|
UTSW |
9 |
32,171,407 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6405:Arhgap32
|
UTSW |
9 |
32,159,784 (GRCm39) |
missense |
probably benign |
0.31 |
|
R6922:Arhgap32
|
UTSW |
9 |
32,063,983 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R7009:Arhgap32
|
UTSW |
9 |
32,157,272 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7137:Arhgap32
|
UTSW |
9 |
32,063,232 (GRCm39) |
missense |
probably benign |
0.32 |
|
R7183:Arhgap32
|
UTSW |
9 |
32,097,679 (GRCm39) |
missense |
probably benign |
0.15 |
|
R7251:Arhgap32
|
UTSW |
9 |
32,119,481 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7287:Arhgap32
|
UTSW |
9 |
32,063,993 (GRCm39) |
missense |
|
|
|
R7289:Arhgap32
|
UTSW |
9 |
32,168,234 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7289:Arhgap32
|
UTSW |
9 |
32,168,233 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7391:Arhgap32
|
UTSW |
9 |
32,093,235 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7408:Arhgap32
|
UTSW |
9 |
32,157,220 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7566:Arhgap32
|
UTSW |
9 |
32,162,018 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7584:Arhgap32
|
UTSW |
9 |
32,168,263 (GRCm39) |
missense |
probably benign |
0.16 |
|
R7653:Arhgap32
|
UTSW |
9 |
32,168,441 (GRCm39) |
missense |
probably benign |
|
|
R7884:Arhgap32
|
UTSW |
9 |
32,171,810 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R8109:Arhgap32
|
UTSW |
9 |
32,093,150 (GRCm39) |
missense |
probably benign |
0.09 |
|
R8131:Arhgap32
|
UTSW |
9 |
32,158,426 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8155:Arhgap32
|
UTSW |
9 |
32,093,196 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8232:Arhgap32
|
UTSW |
9 |
32,168,198 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8303:Arhgap32
|
UTSW |
9 |
32,172,205 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8304:Arhgap32
|
UTSW |
9 |
32,167,233 (GRCm39) |
nonsense |
probably null |
|
|
R8696:Arhgap32
|
UTSW |
9 |
32,159,799 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8832:Arhgap32
|
UTSW |
9 |
32,172,115 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R9112:Arhgap32
|
UTSW |
9 |
32,157,309 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9170:Arhgap32
|
UTSW |
9 |
32,162,039 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R9279:Arhgap32
|
UTSW |
9 |
32,168,655 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9431:Arhgap32
|
UTSW |
9 |
32,170,463 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9522:Arhgap32
|
UTSW |
9 |
32,027,450 (GRCm39) |
missense |
probably benign |
|
|
R9526:Arhgap32
|
UTSW |
9 |
32,172,026 (GRCm39) |
missense |
probably benign |
0.28 |
|
R9661:Arhgap32
|
UTSW |
9 |
32,168,531 (GRCm39) |
missense |
probably benign |
0.01 |
|
X0027:Arhgap32
|
UTSW |
9 |
32,161,937 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
X0063:Arhgap32
|
UTSW |
9 |
32,172,365 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Arhgap32
|
UTSW |
9 |
32,171,976 (GRCm39) |
missense |
probably damaging |
0.97 |
|
| Predicted Primers |
PCR Primer
(F):5'- AATGTCGCCCGAATGTTGGC -3'
(R):5'- AAGGGAGCTGAAGTGCTTC -3'
Sequencing Primer
(F):5'- CGTTAGCTGAGTCTGCACAG -3'
(R):5'- AGCTGAAGTGCTTCTAGCC -3'
|
| Posted On |
2020-06-30 |
Incidental Mutation