Incidental Mutation 'R8094:Myom2'
| ID |
630080 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Myom2
|
| Ensembl Gene |
ENSMUSG00000031461 |
| Gene Name |
myomesin 2 |
| Synonyms |
|
| MMRRC Submission |
067526-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.149)
|
| Stock # |
R8094 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
8 |
| Chromosomal Location |
15107653-15183410 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to T
at 15119418 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Arginine to Leucine
at position 103
(R103L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000033842
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000033842]
|
| AlphaFold |
Q14BI5 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000033842
AA Change: R103L
PolyPhen 2
Score 0.936 (Sensitivity: 0.80; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000033842
Gene: ENSMUSG00000031461
AA Change: R103L
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
34 |
63 |
N/A |
INTRINSIC |
|
low complexity region
|
79 |
87 |
N/A |
INTRINSIC |
|
coiled coil region
|
97 |
129 |
N/A |
INTRINSIC |
|
IG
|
160 |
247 |
7.7e-5 |
SMART |
|
IG
|
284 |
373 |
8.01e-3 |
SMART |
|
FN3
|
383 |
466 |
1.5e-14 |
SMART |
|
FN3
|
511 |
594 |
1.79e-12 |
SMART |
|
FN3
|
612 |
693 |
1.95e-13 |
SMART |
|
FN3
|
711 |
794 |
8.69e-11 |
SMART |
|
FN3
|
813 |
896 |
1.86e-10 |
SMART |
|
IG_like
|
913 |
999 |
1.58e2 |
SMART |
|
Blast:IG_like
|
1021 |
1106 |
1e-44 |
BLAST |
|
IG_like
|
1135 |
1215 |
2.27e1 |
SMART |
|
Blast:IG_like
|
1227 |
1321 |
9e-51 |
BLAST |
|
IGc2
|
1357 |
1425 |
4.96e-8 |
SMART |
|
| Coding Region Coverage |
- 1x: 99.8%
- 3x: 99.7%
- 10x: 99.2%
- 20x: 98.0%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly to M-band constituents of apparent molecular masses of 190 kD and 165 kD. The predicted MYOM2 protein contains 1,465 amino acids. Like MYOM1, MYOM2 has a unique N-terminal domain followed by 12 repeat domains with strong homology to either fibronectin type III or immunoglobulin C2 domains. Protein sequence comparisons suggested that the MYOM2 protein and bovine M protein are identical. [provided by RefSeq, Jul 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 94 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| A230072I06Rik |
T |
A |
8: 12,329,824 (GRCm39) |
L93H |
unknown |
Het |
| A2ml1 |
A |
G |
6: 128,549,045 (GRCm39) |
Y246H |
probably damaging |
Het |
| Akap11 |
C |
A |
14: 78,750,413 (GRCm39) |
C658F |
|
Het |
| Arid2 |
T |
G |
15: 96,266,592 (GRCm39) |
S547A |
possibly damaging |
Het |
| Atf1 |
C |
A |
15: 100,143,170 (GRCm39) |
D46E |
probably damaging |
Het |
| Brca2 |
T |
A |
5: 150,459,634 (GRCm39) |
F303Y |
possibly damaging |
Het |
| Btbd18 |
T |
A |
2: 84,498,260 (GRCm39) |
S633T |
possibly damaging |
Het |
| Btg4 |
T |
G |
9: 51,030,445 (GRCm39) |
F182V |
probably benign |
Het |
| Cacna1e |
G |
A |
1: 154,437,516 (GRCm39) |
S340F |
probably damaging |
Het |
| Camta2 |
A |
G |
11: 70,576,903 (GRCm39) |
W41R |
probably damaging |
Het |
| Cbl |
A |
T |
9: 44,074,696 (GRCm39) |
D455E |
probably benign |
Het |
| Ccdc162 |
A |
T |
10: 41,488,864 (GRCm39) |
D1208E |
probably benign |
Het |
| Cd177 |
A |
T |
7: 24,443,842 (GRCm39) |
M752K |
probably damaging |
Het |
| Cep290 |
A |
T |
10: 100,380,793 (GRCm39) |
H100L |
possibly damaging |
Het |
| Chrnb2 |
T |
A |
3: 89,668,698 (GRCm39) |
I206F |
probably damaging |
Het |
| Cyp2c40 |
A |
G |
19: 39,791,009 (GRCm39) |
L274S |
probably benign |
Het |
| Cyp2c40 |
T |
A |
19: 39,791,015 (GRCm39) |
Y272F |
probably benign |
Het |
| Cyp2d22 |
C |
A |
15: 82,258,556 (GRCm39) |
A102S |
probably benign |
Het |
| Cyp51 |
C |
T |
5: 4,136,490 (GRCm39) |
E435K |
probably benign |
Het |
| Dchs2 |
T |
C |
3: 83,262,929 (GRCm39) |
F3066L |
probably benign |
Het |
| Disp1 |
C |
A |
1: 182,869,192 (GRCm39) |
R1076L |
probably damaging |
Het |
| Dkk2 |
C |
T |
3: 131,791,801 (GRCm39) |
A3V |
probably benign |
Het |
| Dnah7b |
T |
C |
1: 46,165,964 (GRCm39) |
F543S |
probably benign |
Het |
| Dpt |
A |
T |
1: 164,624,481 (GRCm39) |
S61C |
probably damaging |
Het |
| Drg2 |
A |
T |
11: 60,353,096 (GRCm39) |
Y243F |
probably damaging |
Het |
| Dsg2 |
A |
G |
18: 20,716,061 (GRCm39) |
|
probably benign |
Het |
| Dst |
T |
G |
1: 34,228,040 (GRCm39) |
L1878V |
possibly damaging |
Het |
| F5 |
A |
G |
1: 164,036,509 (GRCm39) |
Y1890C |
probably benign |
Het |
| Fat1 |
T |
C |
8: 45,405,739 (GRCm39) |
V830A |
probably damaging |
Het |
| Fat2 |
C |
T |
11: 55,186,965 (GRCm39) |
D1294N |
probably benign |
Het |
| Fbxo15 |
A |
G |
18: 84,983,618 (GRCm39) |
Y322C |
probably benign |
Het |
| Fcsk |
A |
G |
8: 111,622,604 (GRCm39) |
F108S |
probably damaging |
Het |
| Fhit |
A |
T |
14: 10,751,666 (GRCm38) |
N7K |
unknown |
Het |
| Gabrb2 |
A |
G |
11: 42,488,370 (GRCm39) |
I279V |
probably damaging |
Het |
| Galk2 |
T |
C |
2: 125,773,189 (GRCm39) |
F207S |
probably damaging |
Het |
| Gtpbp3 |
C |
T |
8: 71,941,480 (GRCm39) |
L17F |
possibly damaging |
Het |
| Gucy2c |
T |
A |
6: 136,714,446 (GRCm39) |
D460V |
probably benign |
Het |
| Herc1 |
G |
A |
9: 66,400,462 (GRCm39) |
V4329I |
probably damaging |
Het |
| Iqcn |
T |
C |
8: 71,162,067 (GRCm39) |
V420A |
probably benign |
Het |
| Kirrel3 |
G |
A |
9: 34,946,460 (GRCm39) |
V740M |
probably damaging |
Het |
| Macf1 |
C |
A |
4: 123,263,660 (GRCm39) |
V6956L |
probably damaging |
Het |
| Mill1 |
C |
T |
7: 17,989,835 (GRCm39) |
A39V |
probably benign |
Het |
| Mkln1 |
T |
A |
6: 31,469,588 (GRCm39) |
Y599* |
probably null |
Het |
| Mrpl14 |
T |
A |
17: 46,009,039 (GRCm39) |
L46Q |
possibly damaging |
Het |
| Naip2 |
A |
C |
13: 100,298,290 (GRCm39) |
I582S |
probably benign |
Het |
| Ndst2 |
A |
T |
14: 20,778,232 (GRCm39) |
V449D |
probably damaging |
Het |
| Nell1 |
T |
A |
7: 49,770,335 (GRCm39) |
H131Q |
probably benign |
Het |
| Nos3 |
G |
C |
5: 24,572,218 (GRCm39) |
R97P |
probably benign |
Het |
| Npc1 |
A |
T |
18: 12,327,297 (GRCm39) |
F1099L |
probably benign |
Het |
| Nxpe5 |
T |
A |
5: 138,249,802 (GRCm39) |
W531R |
probably damaging |
Het |
| Ogfr |
GGCCAGAGGACCCCAAAAGCCAGGTGGAGCCAGAGGACCCCAAAAGCCAGGTGGAGCCAGAGGACCCCAAAAGCCAGGTGGAGCCAGAGGACCCCAAAAGCCAGGTGGGGCCAGAGGACCCCCAAAGCCAGGTGG |
GGCCAGAGGACCCCAAAAGCCAGGTGGAGCCAGAGGACCCCAAAAGCCAGGTGGAGCCAGAGGACCCCAAAAGCCAGGTGGGGCCAGAGGACCCCCAAAGCCAGGTGG |
2: 180,237,059 (GRCm39) |
|
probably benign |
Het |
| Or1j1 |
A |
T |
2: 36,702,330 (GRCm39) |
L258H |
probably damaging |
Het |
| Or4c110 |
T |
C |
2: 88,832,712 (GRCm39) |
|
probably benign |
Het |
| Or5b98 |
A |
T |
19: 12,931,366 (GRCm39) |
T138S |
probably benign |
Het |
| Or6c210 |
A |
G |
10: 129,495,933 (GRCm39) |
D86G |
probably damaging |
Het |
| Osmr |
T |
C |
15: 6,845,102 (GRCm39) |
N889S |
possibly damaging |
Het |
| Oxct2b |
A |
G |
4: 123,010,301 (GRCm39) |
I74V |
possibly damaging |
Het |
| Pakap |
A |
G |
4: 57,886,319 (GRCm39) |
T859A |
possibly damaging |
Het |
| Phldb3 |
C |
A |
7: 24,326,134 (GRCm39) |
A572D |
probably damaging |
Het |
| Pigr |
A |
G |
1: 130,774,247 (GRCm39) |
E409G |
probably damaging |
Het |
| Ptprs |
T |
C |
17: 56,735,947 (GRCm39) |
E674G |
probably benign |
Het |
| Ptpru |
G |
A |
4: 131,520,903 (GRCm39) |
T801I |
possibly damaging |
Het |
| Ralgapa1 |
T |
A |
12: 55,829,631 (GRCm39) |
D200V |
probably damaging |
Het |
| Rb1cc1 |
A |
T |
1: 6,333,448 (GRCm39) |
R1429* |
probably null |
Het |
| Rictor |
C |
T |
15: 6,801,635 (GRCm39) |
S441L |
probably benign |
Het |
| Rnpep |
A |
T |
1: 135,211,514 (GRCm39) |
L78Q |
probably damaging |
Het |
| Rtn2 |
A |
T |
7: 19,027,791 (GRCm39) |
I394F |
probably damaging |
Het |
| Satb2 |
A |
T |
1: 56,870,623 (GRCm39) |
V572D |
possibly damaging |
Het |
| Sds |
T |
C |
5: 120,617,001 (GRCm39) |
|
probably benign |
Het |
| Serpina10 |
TTCCTCCTCCTCCTCCTCCTCCTCC |
TTCCTCCTCCTCCTCCTCCTCC |
12: 103,595,032 (GRCm39) |
|
probably benign |
Het |
| Sgo2a |
T |
C |
1: 58,056,300 (GRCm39) |
I828T |
possibly damaging |
Het |
| Slc25a33 |
T |
A |
4: 149,840,609 (GRCm39) |
K79N |
probably benign |
Het |
| Slc25a51 |
A |
C |
4: 45,399,783 (GRCm39) |
F136V |
probably benign |
Het |
| Slfn14 |
T |
A |
11: 83,174,119 (GRCm39) |
K291* |
probably null |
Het |
| Sp100 |
A |
G |
1: 85,624,819 (GRCm39) |
K403E |
possibly damaging |
Het |
| Spaca1 |
C |
T |
4: 34,049,837 (GRCm39) |
E54K |
possibly damaging |
Het |
| Sympk |
T |
G |
7: 18,787,373 (GRCm39) |
|
probably null |
Het |
| Syne1 |
A |
T |
10: 5,067,031 (GRCm39) |
V7078D |
probably damaging |
Het |
| Tas2r121 |
T |
A |
6: 132,677,772 (GRCm39) |
I67L |
probably benign |
Het |
| Tha1 |
T |
C |
11: 117,759,323 (GRCm39) |
K389E |
probably benign |
Het |
| Thbs2 |
T |
A |
17: 14,900,584 (GRCm39) |
Q541L |
probably benign |
Het |
| Tmem161b |
C |
A |
13: 84,370,537 (GRCm39) |
|
probably benign |
Het |
| Tmem94 |
T |
C |
11: 115,679,218 (GRCm39) |
|
probably null |
Het |
| Tnfsf13 |
A |
G |
11: 69,575,983 (GRCm39) |
C35R |
probably damaging |
Het |
| Trcg1 |
C |
A |
9: 57,149,564 (GRCm39) |
Q379K |
probably benign |
Het |
| Ubr4 |
T |
C |
4: 139,168,007 (GRCm39) |
S1507P |
probably damaging |
Het |
| Uckl1 |
A |
G |
2: 181,215,049 (GRCm39) |
I268T |
probably damaging |
Het |
| Uvrag |
T |
C |
7: 98,641,174 (GRCm39) |
K289E |
possibly damaging |
Het |
| Vmn2r104 |
C |
A |
17: 20,250,483 (GRCm39) |
C596F |
possibly damaging |
Het |
| Vmn2r11 |
A |
T |
5: 109,201,626 (GRCm39) |
F293I |
probably damaging |
Het |
| Vps13b |
T |
A |
15: 35,669,052 (GRCm39) |
|
probably null |
Het |
| Wipf1 |
G |
A |
2: 73,267,879 (GRCm39) |
P173L |
possibly damaging |
Het |
| Zfp217 |
G |
A |
2: 169,961,571 (GRCm39) |
S252F |
possibly damaging |
Het |
| Zscan4f |
T |
A |
7: 11,135,154 (GRCm39) |
C187S |
possibly damaging |
Het |
|
| Other mutations in Myom2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00422:Myom2
|
APN |
8 |
15,119,490 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00426:Myom2
|
APN |
8 |
15,119,502 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00503:Myom2
|
APN |
8 |
15,164,289 (GRCm39) |
splice site |
probably null |
|
|
IGL01515:Myom2
|
APN |
8 |
15,172,655 (GRCm39) |
missense |
probably benign |
0.15 |
|
IGL01649:Myom2
|
APN |
8 |
15,163,755 (GRCm39) |
missense |
probably benign |
0.24 |
|
IGL01658:Myom2
|
APN |
8 |
15,127,880 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01786:Myom2
|
APN |
8 |
15,156,330 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01924:Myom2
|
APN |
8 |
15,119,685 (GRCm39) |
missense |
probably benign |
0.37 |
|
IGL01929:Myom2
|
APN |
8 |
15,167,698 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02016:Myom2
|
APN |
8 |
15,175,195 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02511:Myom2
|
APN |
8 |
15,115,743 (GRCm39) |
missense |
probably benign |
|
|
IGL02558:Myom2
|
APN |
8 |
15,164,237 (GRCm39) |
missense |
probably benign |
0.31 |
|
IGL02944:Myom2
|
APN |
8 |
15,154,065 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
IGL03052:Myom2
|
APN |
8 |
15,173,442 (GRCm39) |
splice site |
probably benign |
|
|
IGL03195:Myom2
|
APN |
8 |
15,161,844 (GRCm39) |
nonsense |
probably null |
|
|
IGL03288:Myom2
|
APN |
8 |
15,172,679 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03402:Myom2
|
APN |
8 |
15,115,731 (GRCm39) |
missense |
probably benign |
|
|
yomama
|
UTSW |
8 |
15,182,895 (GRCm39) |
missense |
probably benign |
0.10 |
|
yoyoma
|
UTSW |
8 |
15,182,667 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0069:Myom2
|
UTSW |
8 |
15,167,624 (GRCm39) |
missense |
probably benign |
|
|
R0116:Myom2
|
UTSW |
8 |
15,167,633 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0131:Myom2
|
UTSW |
8 |
15,133,329 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0373:Myom2
|
UTSW |
8 |
15,148,419 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R0463:Myom2
|
UTSW |
8 |
15,154,123 (GRCm39) |
missense |
probably benign |
0.09 |
|
R0544:Myom2
|
UTSW |
8 |
15,119,796 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0629:Myom2
|
UTSW |
8 |
15,119,783 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0634:Myom2
|
UTSW |
8 |
15,169,216 (GRCm39) |
splice site |
probably benign |
|
|
R0645:Myom2
|
UTSW |
8 |
15,167,698 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0730:Myom2
|
UTSW |
8 |
15,149,326 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0744:Myom2
|
UTSW |
8 |
15,182,924 (GRCm39) |
nonsense |
probably null |
|
|
R0836:Myom2
|
UTSW |
8 |
15,182,924 (GRCm39) |
nonsense |
probably null |
|
|
R1033:Myom2
|
UTSW |
8 |
15,158,934 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1103:Myom2
|
UTSW |
8 |
15,160,827 (GRCm39) |
missense |
probably benign |
0.22 |
|
R1110:Myom2
|
UTSW |
8 |
15,172,413 (GRCm39) |
missense |
probably benign |
0.44 |
|
R1208:Myom2
|
UTSW |
8 |
15,134,631 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1208:Myom2
|
UTSW |
8 |
15,134,631 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1353:Myom2
|
UTSW |
8 |
15,156,424 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1530:Myom2
|
UTSW |
8 |
15,172,384 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1544:Myom2
|
UTSW |
8 |
15,154,059 (GRCm39) |
splice site |
probably benign |
|
|
R1576:Myom2
|
UTSW |
8 |
15,134,556 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1758:Myom2
|
UTSW |
8 |
15,115,795 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1884:Myom2
|
UTSW |
8 |
15,164,278 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1908:Myom2
|
UTSW |
8 |
15,131,023 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1962:Myom2
|
UTSW |
8 |
15,182,599 (GRCm39) |
splice site |
probably null |
|
|
R1977:Myom2
|
UTSW |
8 |
15,135,263 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R2018:Myom2
|
UTSW |
8 |
15,181,151 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2049:Myom2
|
UTSW |
8 |
15,156,379 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R2155:Myom2
|
UTSW |
8 |
15,134,555 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2314:Myom2
|
UTSW |
8 |
15,113,927 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2350:Myom2
|
UTSW |
8 |
15,158,835 (GRCm39) |
missense |
probably benign |
0.09 |
|
R2358:Myom2
|
UTSW |
8 |
15,162,018 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R2904:Myom2
|
UTSW |
8 |
15,148,348 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3418:Myom2
|
UTSW |
8 |
15,135,294 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3606:Myom2
|
UTSW |
8 |
15,119,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3607:Myom2
|
UTSW |
8 |
15,119,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3735:Myom2
|
UTSW |
8 |
15,119,676 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3756:Myom2
|
UTSW |
8 |
15,152,650 (GRCm39) |
missense |
probably benign |
0.11 |
|
R3902:Myom2
|
UTSW |
8 |
15,154,165 (GRCm39) |
missense |
probably benign |
|
|
R3951:Myom2
|
UTSW |
8 |
15,134,556 (GRCm39) |
missense |
probably benign |
0.35 |
|
R4240:Myom2
|
UTSW |
8 |
15,182,895 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4361:Myom2
|
UTSW |
8 |
15,162,018 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R4581:Myom2
|
UTSW |
8 |
15,156,459 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4736:Myom2
|
UTSW |
8 |
15,131,271 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5010:Myom2
|
UTSW |
8 |
15,133,310 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5108:Myom2
|
UTSW |
8 |
15,182,667 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5370:Myom2
|
UTSW |
8 |
15,149,343 (GRCm39) |
missense |
probably benign |
0.10 |
|
R5427:Myom2
|
UTSW |
8 |
15,163,764 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5498:Myom2
|
UTSW |
8 |
15,179,142 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5504:Myom2
|
UTSW |
8 |
15,178,879 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5567:Myom2
|
UTSW |
8 |
15,152,546 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5743:Myom2
|
UTSW |
8 |
15,130,914 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R5745:Myom2
|
UTSW |
8 |
15,172,705 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5844:Myom2
|
UTSW |
8 |
15,181,182 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5854:Myom2
|
UTSW |
8 |
15,158,478 (GRCm39) |
missense |
probably benign |
|
|
R6141:Myom2
|
UTSW |
8 |
15,113,903 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6209:Myom2
|
UTSW |
8 |
15,154,173 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R6248:Myom2
|
UTSW |
8 |
15,148,472 (GRCm39) |
splice site |
probably null |
|
|
R6378:Myom2
|
UTSW |
8 |
15,149,356 (GRCm39) |
missense |
probably benign |
0.11 |
|
R6829:Myom2
|
UTSW |
8 |
15,172,643 (GRCm39) |
nonsense |
probably null |
|
|
R6913:Myom2
|
UTSW |
8 |
15,115,710 (GRCm39) |
missense |
probably benign |
|
|
R6957:Myom2
|
UTSW |
8 |
15,167,741 (GRCm39) |
missense |
probably null |
0.42 |
|
R6958:Myom2
|
UTSW |
8 |
15,167,741 (GRCm39) |
missense |
probably null |
0.42 |
|
R6960:Myom2
|
UTSW |
8 |
15,167,741 (GRCm39) |
missense |
probably null |
0.42 |
|
R6961:Myom2
|
UTSW |
8 |
15,167,741 (GRCm39) |
missense |
probably null |
0.42 |
|
R6962:Myom2
|
UTSW |
8 |
15,167,741 (GRCm39) |
missense |
probably null |
0.42 |
|
R6999:Myom2
|
UTSW |
8 |
15,134,531 (GRCm39) |
missense |
probably benign |
0.22 |
|
R7148:Myom2
|
UTSW |
8 |
15,134,577 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R7210:Myom2
|
UTSW |
8 |
15,154,114 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7298:Myom2
|
UTSW |
8 |
15,148,411 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7463:Myom2
|
UTSW |
8 |
15,167,679 (GRCm39) |
missense |
probably null |
0.94 |
|
R7535:Myom2
|
UTSW |
8 |
15,167,679 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7573:Myom2
|
UTSW |
8 |
15,172,450 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7590:Myom2
|
UTSW |
8 |
15,167,679 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7690:Myom2
|
UTSW |
8 |
15,161,717 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7794:Myom2
|
UTSW |
8 |
15,133,259 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7822:Myom2
|
UTSW |
8 |
15,158,454 (GRCm39) |
missense |
probably benign |
|
|
R7948:Myom2
|
UTSW |
8 |
15,135,306 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8268:Myom2
|
UTSW |
8 |
15,179,157 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8292:Myom2
|
UTSW |
8 |
15,182,888 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8514:Myom2
|
UTSW |
8 |
15,175,153 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R8539:Myom2
|
UTSW |
8 |
15,164,254 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8790:Myom2
|
UTSW |
8 |
15,169,242 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8824:Myom2
|
UTSW |
8 |
15,164,169 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R8895:Myom2
|
UTSW |
8 |
15,152,589 (GRCm39) |
nonsense |
probably null |
|
|
R9024:Myom2
|
UTSW |
8 |
15,113,936 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9129:Myom2
|
UTSW |
8 |
15,154,068 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9224:Myom2
|
UTSW |
8 |
15,178,804 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R9237:Myom2
|
UTSW |
8 |
15,152,591 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R9321:Myom2
|
UTSW |
8 |
15,172,464 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9341:Myom2
|
UTSW |
8 |
15,134,633 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9343:Myom2
|
UTSW |
8 |
15,134,633 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9375:Myom2
|
UTSW |
8 |
15,149,210 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9455:Myom2
|
UTSW |
8 |
15,156,293 (GRCm39) |
missense |
probably benign |
0.31 |
|
R9563:Myom2
|
UTSW |
8 |
15,158,399 (GRCm39) |
nonsense |
probably null |
|
|
R9565:Myom2
|
UTSW |
8 |
15,158,399 (GRCm39) |
nonsense |
probably null |
|
|
RF001:Myom2
|
UTSW |
8 |
15,131,418 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
| Predicted Primers |
PCR Primer
(F):5'- AAAACGTTGTTTGGCTTTTCCC -3'
(R):5'- ACGCCAGATTGTCTTCCACC -3'
Sequencing Primer
(F):5'- GTTGTTTGGCTTTTCCCCATCATC -3'
(R):5'- AGGAGCAGCCCACGGTTAG -3'
|
| Posted On |
2020-06-30 |
Incidental Mutation