Incidental Mutation 'R8098:Kif13a'
| ID |
630346 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Kif13a
|
| Ensembl Gene |
ENSMUSG00000021375 |
| Gene Name |
kinesin family member 13A |
| Synonyms |
4930505I07Rik, N-3 kinesin |
| MMRRC Submission |
067530-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.268)
|
| Stock # |
R8098 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
13 |
| Chromosomal Location |
46902563-47083343 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 46968780 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Serine
at position 354
(N354S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000055304
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000056978]
[ENSMUST00000225591]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000056978
AA Change: N354S
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000055304
Gene: ENSMUSG00000021375
AA Change: N354S
| Domain | Start | End | E-Value | Type |
|---|
|
KISc
|
3 |
360 |
2.69e-175 |
SMART |
|
low complexity region
|
368 |
381 |
N/A |
INTRINSIC |
|
low complexity region
|
391 |
406 |
N/A |
INTRINSIC |
|
FHA
|
469 |
519 |
7.16e-2 |
SMART |
|
coiled coil region
|
605 |
639 |
N/A |
INTRINSIC |
|
coiled coil region
|
664 |
704 |
N/A |
INTRINSIC |
|
Pfam:KIF1B
|
748 |
792 |
1.7e-19 |
PFAM |
|
low complexity region
|
840 |
854 |
N/A |
INTRINSIC |
|
low complexity region
|
903 |
915 |
N/A |
INTRINSIC |
|
Pfam:DUF3694
|
1003 |
1270 |
2.2e-39 |
PFAM |
|
low complexity region
|
1401 |
1412 |
N/A |
INTRINSIC |
|
low complexity region
|
1475 |
1492 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000225591
AA Change: N291S
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.8%
- 10x: 99.3%
- 20x: 98.4%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the kinesin family of microtubule-based motor proteins that function in the positioning of endosomes. This family member can direct mannose-6-phosphate receptor-containing vesicles from the trans-Golgi network to the plasma membrane, and it is necessary for the steady-state distribution of late endosomes/lysosomes. It is also required for the translocation of FYVE-CENT and TTC19 from the centrosome to the midbody during cytokinesis, and it plays a role in melanosome maturation. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased anxiety. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 92 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 3425401B19Rik |
A |
G |
14: 32,384,618 (GRCm39) |
L449P |
probably damaging |
Het |
| Abca15 |
A |
G |
7: 119,960,619 (GRCm39) |
S694G |
probably benign |
Het |
| Abcc6 |
A |
G |
7: 45,646,089 (GRCm39) |
L800P |
probably damaging |
Het |
| Adam15 |
T |
A |
3: 89,251,193 (GRCm39) |
D504V |
probably damaging |
Het |
| Adnp |
T |
C |
2: 168,024,452 (GRCm39) |
T948A |
probably benign |
Het |
| Akap11 |
T |
C |
14: 78,750,362 (GRCm39) |
D675G |
|
Het |
| Atp13a3 |
A |
C |
16: 30,173,115 (GRCm39) |
V254G |
possibly damaging |
Het |
| Atp1a1 |
A |
G |
3: 101,489,365 (GRCm39) |
I749T |
probably damaging |
Het |
| B3glct |
T |
A |
5: 149,673,965 (GRCm39) |
Y369* |
probably null |
Het |
| Bms1 |
C |
T |
6: 118,361,219 (GRCm39) |
R1204H |
probably damaging |
Het |
| Btla |
T |
A |
16: 45,064,612 (GRCm39) |
L188* |
probably null |
Het |
| Btn2a2 |
A |
G |
13: 23,666,058 (GRCm39) |
V258A |
probably benign |
Het |
| C1ra |
G |
A |
6: 124,494,684 (GRCm39) |
E316K |
probably benign |
Het |
| Cacna1g |
T |
C |
11: 94,307,338 (GRCm39) |
H1782R |
probably benign |
Het |
| Calcoco1 |
T |
C |
15: 102,624,759 (GRCm39) |
D172G |
probably benign |
Het |
| Ccdc192 |
A |
T |
18: 57,800,403 (GRCm39) |
I185L |
probably benign |
Het |
| Ciart |
G |
A |
3: 95,788,656 (GRCm39) |
P61L |
probably damaging |
Het |
| Ckap4 |
A |
G |
10: 84,369,499 (GRCm39) |
S78P |
probably damaging |
Het |
| Col6a3 |
A |
T |
1: 90,731,383 (GRCm39) |
D1623E |
probably benign |
Het |
| Col7a1 |
A |
G |
9: 108,785,763 (GRCm39) |
T411A |
unknown |
Het |
| Cpt1a |
A |
C |
19: 3,420,849 (GRCm39) |
I436L |
probably benign |
Het |
| Cyp2c23 |
T |
A |
19: 44,004,242 (GRCm39) |
I173F |
probably benign |
Het |
| Dcun1d2 |
T |
C |
8: 13,311,396 (GRCm39) |
T198A |
probably benign |
Het |
| Ddx50 |
A |
C |
10: 62,460,922 (GRCm39) |
|
probably null |
Het |
| Depdc1b |
A |
G |
13: 108,460,593 (GRCm39) |
T68A |
probably damaging |
Het |
| Dgkq |
G |
A |
5: 108,800,334 (GRCm39) |
R546W |
probably damaging |
Het |
| Dmbt1 |
G |
A |
7: 130,710,188 (GRCm39) |
W1493* |
probably null |
Het |
| Dnah17 |
A |
G |
11: 117,941,193 (GRCm39) |
S3219P |
probably damaging |
Het |
| Egf |
T |
A |
3: 129,484,486 (GRCm39) |
Y986F |
probably benign |
Het |
| Ell3 |
TCTCCTC |
TCTC |
2: 121,269,937 (GRCm39) |
|
probably benign |
Het |
| Ep400 |
A |
T |
5: 110,841,117 (GRCm39) |
M1805K |
unknown |
Het |
| Exoc3 |
A |
G |
13: 74,320,271 (GRCm39) |
M730T |
probably benign |
Het |
| Fbxl13 |
T |
A |
5: 21,825,716 (GRCm39) |
M129L |
probably benign |
Het |
| Fem1al |
A |
G |
11: 29,774,450 (GRCm39) |
S336P |
possibly damaging |
Het |
| Gins4 |
T |
A |
8: 23,727,037 (GRCm39) |
M19L |
probably benign |
Het |
| Gm3238 |
T |
C |
10: 77,606,474 (GRCm39) |
N229S |
unknown |
Het |
| Gpd2 |
T |
A |
2: 57,180,020 (GRCm39) |
V89D |
possibly damaging |
Het |
| Hectd4 |
G |
A |
5: 121,459,461 (GRCm39) |
V777I |
possibly damaging |
Het |
| Hgf |
T |
A |
5: 16,766,059 (GRCm39) |
V65E |
probably benign |
Het |
| Hnrnpdl |
A |
G |
5: 100,185,779 (GRCm39) |
S169P |
probably benign |
Het |
| Igfbp3 |
T |
C |
11: 7,160,104 (GRCm39) |
D183G |
possibly damaging |
Het |
| Il16 |
A |
G |
7: 83,295,767 (GRCm39) |
V1134A |
probably damaging |
Het |
| Kcnn4 |
A |
G |
7: 24,083,504 (GRCm39) |
D395G |
probably damaging |
Het |
| Kctd17 |
CAGCTGGAGGAGC |
CAGC |
15: 78,321,113 (GRCm39) |
|
probably benign |
Het |
| Lrp1 |
C |
T |
10: 127,410,324 (GRCm39) |
R1474Q |
possibly damaging |
Het |
| Map3k9 |
T |
C |
12: 81,780,888 (GRCm39) |
Q424R |
probably damaging |
Het |
| Mkx |
A |
C |
18: 6,992,784 (GRCm39) |
S167A |
possibly damaging |
Het |
| Ms4a14 |
A |
G |
19: 11,281,979 (GRCm39) |
F193S |
possibly damaging |
Het |
| Myo18a |
A |
T |
11: 77,736,227 (GRCm39) |
D1508V |
probably damaging |
Het |
| Nek4 |
T |
A |
14: 30,685,908 (GRCm39) |
N273K |
probably benign |
Het |
| Nipal3 |
A |
T |
4: 135,179,709 (GRCm39) |
V403D |
possibly damaging |
Het |
| Nlrp6 |
G |
A |
7: 140,503,168 (GRCm39) |
V425M |
probably damaging |
Het |
| Or13p4 |
A |
T |
4: 118,547,406 (GRCm39) |
V81E |
possibly damaging |
Het |
| Or14j6 |
A |
G |
17: 38,215,250 (GRCm39) |
D271G |
probably damaging |
Het |
| Or4c122 |
T |
A |
2: 89,079,652 (GRCm39) |
M117L |
possibly damaging |
Het |
| Or9k2 |
T |
C |
10: 129,998,916 (GRCm39) |
K93R |
probably benign |
Het |
| Otub1 |
A |
T |
19: 7,181,794 (GRCm39) |
D27E |
probably damaging |
Het |
| Pcnx2 |
T |
C |
8: 126,495,040 (GRCm39) |
D1607G |
probably damaging |
Het |
| Pde2a |
A |
G |
7: 101,071,178 (GRCm39) |
Y16C |
probably benign |
Het |
| Pkd1l3 |
GACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCA |
GACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCA |
8: 110,350,827 (GRCm39) |
|
probably benign |
Het |
| Prph2 |
A |
T |
17: 47,230,892 (GRCm39) |
M262L |
probably benign |
Het |
| Pxdn |
C |
T |
12: 30,056,601 (GRCm39) |
L1271F |
probably damaging |
Het |
| Rnf10 |
A |
C |
5: 115,389,438 (GRCm39) |
I243S |
probably damaging |
Het |
| Samd9l |
T |
C |
6: 3,375,549 (GRCm39) |
I571V |
probably damaging |
Het |
| Scube1 |
C |
T |
15: 83,543,289 (GRCm39) |
G183D |
probably damaging |
Het |
| Sidt2 |
A |
G |
9: 45,857,028 (GRCm39) |
V426A |
probably benign |
Het |
| Slc20a1 |
T |
C |
2: 129,051,041 (GRCm39) |
L566P |
probably damaging |
Het |
| Slc22a3 |
A |
G |
17: 12,642,619 (GRCm39) |
|
probably null |
Het |
| Snx11 |
G |
T |
11: 96,661,500 (GRCm39) |
S168R |
probably benign |
Het |
| Snx5 |
T |
C |
2: 144,097,482 (GRCm39) |
N218D |
probably benign |
Het |
| Snx7 |
A |
T |
3: 117,632,583 (GRCm39) |
D169E |
probably benign |
Het |
| Soat1 |
A |
G |
1: 156,274,180 (GRCm39) |
L77P |
probably damaging |
Het |
| Sucnr1 |
T |
A |
3: 59,994,162 (GRCm39) |
V230E |
probably damaging |
Het |
| Supv3l1 |
T |
C |
10: 62,265,282 (GRCm39) |
K753E |
probably benign |
Het |
| Tango6 |
T |
G |
8: 107,468,990 (GRCm39) |
L829V |
possibly damaging |
Het |
| Tek |
T |
C |
4: 94,715,907 (GRCm39) |
V443A |
probably benign |
Het |
| Tet1 |
A |
T |
10: 62,714,859 (GRCm39) |
L312Q |
probably damaging |
Het |
| Tgm1 |
A |
T |
14: 55,947,991 (GRCm39) |
N269K |
probably damaging |
Het |
| Thrb |
A |
T |
14: 18,008,645 (GRCm38) |
D168V |
probably damaging |
Het |
| Tk2 |
C |
T |
8: 104,957,804 (GRCm39) |
V181I |
probably benign |
Het |
| Tm6sf2 |
T |
C |
8: 70,526,972 (GRCm39) |
L47P |
probably damaging |
Het |
| Tmcc3 |
T |
A |
10: 94,415,078 (GRCm39) |
M291K |
probably benign |
Het |
| Tnfrsf21 |
A |
G |
17: 43,350,790 (GRCm39) |
E318G |
probably benign |
Het |
| Ttc7 |
T |
C |
17: 87,641,756 (GRCm39) |
V451A |
probably benign |
Het |
| Ugt2b36 |
A |
T |
5: 87,240,252 (GRCm39) |
D44E |
probably benign |
Het |
| Usp17la |
G |
T |
7: 104,510,138 (GRCm39) |
V248L |
probably damaging |
Het |
| Utp20 |
A |
C |
10: 88,588,810 (GRCm39) |
I2453S |
probably benign |
Het |
| Wdr91 |
A |
T |
6: 34,863,817 (GRCm39) |
I566N |
possibly damaging |
Het |
| Zfp282 |
A |
G |
6: 47,867,652 (GRCm39) |
D276G |
probably benign |
Het |
| Zfp764l1 |
C |
T |
7: 126,992,496 (GRCm39) |
C38Y |
probably null |
Het |
| Zfp866 |
T |
C |
8: 70,218,628 (GRCm39) |
K331E |
probably benign |
Het |
| Zkscan17 |
A |
T |
11: 59,394,410 (GRCm39) |
W64R |
possibly damaging |
Het |
|
| Other mutations in Kif13a |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01084:Kif13a
|
APN |
13 |
46,904,110 (GRCm39) |
splice site |
probably benign |
|
|
IGL01433:Kif13a
|
APN |
13 |
46,926,384 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01528:Kif13a
|
APN |
13 |
47,018,313 (GRCm39) |
splice site |
probably benign |
|
|
IGL01536:Kif13a
|
APN |
13 |
46,905,765 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01620:Kif13a
|
APN |
13 |
47,018,296 (GRCm39) |
missense |
probably benign |
|
|
IGL02020:Kif13a
|
APN |
13 |
46,947,495 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02142:Kif13a
|
APN |
13 |
46,925,011 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL02375:Kif13a
|
APN |
13 |
46,978,698 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02407:Kif13a
|
APN |
13 |
46,938,769 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02476:Kif13a
|
APN |
13 |
46,938,772 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03038:Kif13a
|
APN |
13 |
46,926,314 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03053:Kif13a
|
APN |
13 |
46,905,564 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03366:Kif13a
|
APN |
13 |
46,918,099 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0025:Kif13a
|
UTSW |
13 |
46,939,987 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0106:Kif13a
|
UTSW |
13 |
46,978,823 (GRCm39) |
splice site |
probably benign |
|
|
R0106:Kif13a
|
UTSW |
13 |
46,978,823 (GRCm39) |
splice site |
probably benign |
|
|
R0135:Kif13a
|
UTSW |
13 |
46,947,419 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0137:Kif13a
|
UTSW |
13 |
46,918,079 (GRCm39) |
missense |
probably benign |
0.38 |
|
R0243:Kif13a
|
UTSW |
13 |
46,944,827 (GRCm39) |
missense |
probably benign |
0.24 |
|
R0346:Kif13a
|
UTSW |
13 |
46,967,695 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R0403:Kif13a
|
UTSW |
13 |
46,944,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0492:Kif13a
|
UTSW |
13 |
46,966,218 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0607:Kif13a
|
UTSW |
13 |
46,956,187 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0631:Kif13a
|
UTSW |
13 |
46,932,364 (GRCm39) |
unclassified |
probably benign |
|
|
R0654:Kif13a
|
UTSW |
13 |
46,966,218 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0697:Kif13a
|
UTSW |
13 |
47,001,813 (GRCm39) |
missense |
probably benign |
0.19 |
|
R0699:Kif13a
|
UTSW |
13 |
46,952,689 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R0715:Kif13a
|
UTSW |
13 |
46,966,299 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0834:Kif13a
|
UTSW |
13 |
46,967,712 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0903:Kif13a
|
UTSW |
13 |
47,082,735 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R1419:Kif13a
|
UTSW |
13 |
46,978,711 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1428:Kif13a
|
UTSW |
13 |
46,944,987 (GRCm39) |
splice site |
probably benign |
|
|
R1449:Kif13a
|
UTSW |
13 |
46,966,212 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1463:Kif13a
|
UTSW |
13 |
47,083,088 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R1541:Kif13a
|
UTSW |
13 |
46,962,689 (GRCm39) |
missense |
probably benign |
|
|
R1579:Kif13a
|
UTSW |
13 |
46,906,332 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1582:Kif13a
|
UTSW |
13 |
46,947,398 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1644:Kif13a
|
UTSW |
13 |
46,947,398 (GRCm39) |
missense |
probably benign |
0.31 |
|
R1752:Kif13a
|
UTSW |
13 |
46,951,885 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1755:Kif13a
|
UTSW |
13 |
46,927,154 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R1755:Kif13a
|
UTSW |
13 |
46,906,089 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R1858:Kif13a
|
UTSW |
13 |
47,018,314 (GRCm39) |
splice site |
probably benign |
|
|
R1891:Kif13a
|
UTSW |
13 |
47,082,695 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R1902:Kif13a
|
UTSW |
13 |
46,941,638 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1928:Kif13a
|
UTSW |
13 |
46,966,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1960:Kif13a
|
UTSW |
13 |
47,018,314 (GRCm39) |
splice site |
probably benign |
|
|
R1961:Kif13a
|
UTSW |
13 |
47,018,314 (GRCm39) |
splice site |
probably benign |
|
|
R2016:Kif13a
|
UTSW |
13 |
46,964,275 (GRCm39) |
missense |
probably benign |
0.13 |
|
R2139:Kif13a
|
UTSW |
13 |
46,905,945 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R2174:Kif13a
|
UTSW |
13 |
46,922,652 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2407:Kif13a
|
UTSW |
13 |
46,930,573 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2504:Kif13a
|
UTSW |
13 |
46,967,676 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3122:Kif13a
|
UTSW |
13 |
46,918,072 (GRCm39) |
splice site |
probably benign |
|
|
R3499:Kif13a
|
UTSW |
13 |
46,978,815 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3905:Kif13a
|
UTSW |
13 |
46,956,166 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4474:Kif13a
|
UTSW |
13 |
46,967,631 (GRCm39) |
splice site |
probably null |
|
|
R4771:Kif13a
|
UTSW |
13 |
46,978,687 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4838:Kif13a
|
UTSW |
13 |
46,980,224 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4924:Kif13a
|
UTSW |
13 |
47,083,075 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4931:Kif13a
|
UTSW |
13 |
46,962,531 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4980:Kif13a
|
UTSW |
13 |
46,906,222 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R4992:Kif13a
|
UTSW |
13 |
46,930,639 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5047:Kif13a
|
UTSW |
13 |
46,941,561 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5054:Kif13a
|
UTSW |
13 |
46,956,122 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5141:Kif13a
|
UTSW |
13 |
46,906,197 (GRCm39) |
missense |
probably benign |
|
|
R5329:Kif13a
|
UTSW |
13 |
46,928,877 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5429:Kif13a
|
UTSW |
13 |
46,926,245 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5499:Kif13a
|
UTSW |
13 |
46,986,212 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5509:Kif13a
|
UTSW |
13 |
46,905,591 (GRCm39) |
missense |
probably benign |
0.13 |
|
R5594:Kif13a
|
UTSW |
13 |
46,906,338 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5921:Kif13a
|
UTSW |
13 |
46,978,776 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5964:Kif13a
|
UTSW |
13 |
46,925,000 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6115:Kif13a
|
UTSW |
13 |
46,954,789 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6317:Kif13a
|
UTSW |
13 |
46,980,233 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6318:Kif13a
|
UTSW |
13 |
46,968,683 (GRCm39) |
splice site |
probably null |
|
|
R6393:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6394:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6395:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6735:Kif13a
|
UTSW |
13 |
46,906,222 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R7037:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7038:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7039:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7237:Kif13a
|
UTSW |
13 |
46,962,632 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7285:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7286:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7287:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7341:Kif13a
|
UTSW |
13 |
46,980,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7693:Kif13a
|
UTSW |
13 |
46,904,089 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7761:Kif13a
|
UTSW |
13 |
46,951,955 (GRCm39) |
missense |
probably benign |
|
|
R8171:Kif13a
|
UTSW |
13 |
46,932,444 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8271:Kif13a
|
UTSW |
13 |
46,906,057 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8806:Kif13a
|
UTSW |
13 |
46,914,813 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R8871:Kif13a
|
UTSW |
13 |
46,984,279 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8877:Kif13a
|
UTSW |
13 |
46,954,921 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R8906:Kif13a
|
UTSW |
13 |
46,927,154 (GRCm39) |
missense |
probably benign |
0.17 |
|
R9028:Kif13a
|
UTSW |
13 |
46,951,841 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9058:Kif13a
|
UTSW |
13 |
46,944,941 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9062:Kif13a
|
UTSW |
13 |
46,941,536 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9070:Kif13a
|
UTSW |
13 |
46,905,934 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9083:Kif13a
|
UTSW |
13 |
46,966,263 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9250:Kif13a
|
UTSW |
13 |
46,928,909 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9328:Kif13a
|
UTSW |
13 |
46,951,838 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9360:Kif13a
|
UTSW |
13 |
46,962,472 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9369:Kif13a
|
UTSW |
13 |
46,940,099 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9589:Kif13a
|
UTSW |
13 |
46,956,020 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9749:Kif13a
|
UTSW |
13 |
46,914,227 (GRCm39) |
missense |
probably damaging |
0.96 |
|
X0013:Kif13a
|
UTSW |
13 |
47,082,746 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
| Predicted Primers |
PCR Primer
(F):5'- AATCACATGGCTAGGACCCAG -3'
(R):5'- AGTCAAATGTGGCTATTTCCTGC -3'
Sequencing Primer
(F):5'- CTAGGACCCAGGGCCGC -3'
(R):5'- CCTGCTTTTATTGGGTGCTGAC -3'
|
| Posted On |
2020-06-30 |
Incidental Mutation