Incidental Mutation 'R8111:Dync2i2'
| ID |
630848 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dync2i2
|
| Ensembl Gene |
ENSMUSG00000039715 |
| Gene Name |
dynein 2 intermediate chain 2 |
| Synonyms |
3200002I06Rik, Wdr34 |
| MMRRC Submission |
067540-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.544)
|
| Stock # |
R8111 (G1)
|
| Quality Score |
208.009 |
|
Status
|
Not validated
|
| Chromosome |
2 |
| Chromosomal Location |
29921563-29938891 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to A
at 29921859 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Alanine to Serine
at position 501
(A501S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000109340
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000046257]
[ENSMUST00000095083]
[ENSMUST00000100225]
[ENSMUST00000113711]
[ENSMUST00000113717]
[ENSMUST00000113719]
[ENSMUST00000129241]
|
| AlphaFold |
Q5U4F6 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000046257
|
| SMART Domains |
Protein: ENSMUSP00000047792
Gene: ENSMUSG00000057738
| Domain | Start | End | E-Value | Type |
|---|
|
SPEC
|
47 |
146 |
2.1e-30 |
SMART |
|
SPEC
|
152 |
252 |
2.6e-35 |
SMART |
|
SPEC
|
258 |
358 |
4.93e-36 |
SMART |
|
SPEC
|
364 |
464 |
1.08e-27 |
SMART |
|
SPEC
|
470 |
570 |
9.01e-30 |
SMART |
|
SPEC
|
576 |
675 |
3.52e-32 |
SMART |
|
SPEC
|
681 |
781 |
2.15e-36 |
SMART |
|
SPEC
|
787 |
887 |
2.45e-40 |
SMART |
|
SPEC
|
893 |
1068 |
1.18e-24 |
SMART |
|
SH3
|
970 |
1025 |
8.24e-18 |
SMART |
|
SPEC
|
1074 |
1210 |
6.52e-27 |
SMART |
|
SPEC
|
1216 |
1316 |
1.44e-37 |
SMART |
|
SPEC
|
1322 |
1422 |
4.43e-29 |
SMART |
|
SPEC
|
1428 |
1528 |
7.54e-32 |
SMART |
|
SPEC
|
1534 |
1635 |
9.65e-30 |
SMART |
|
SPEC
|
1641 |
1741 |
2.32e-32 |
SMART |
|
SPEC
|
1747 |
1847 |
6.98e-36 |
SMART |
|
SPEC
|
1853 |
1953 |
1.53e-32 |
SMART |
|
SPEC
|
1959 |
2060 |
6.23e-24 |
SMART |
|
SPEC
|
2074 |
2174 |
2.08e-11 |
SMART |
|
SPEC
|
2188 |
2289 |
1.07e-4 |
SMART |
|
EFh
|
2307 |
2335 |
5.78e-7 |
SMART |
|
EFh
|
2350 |
2378 |
3.85e-3 |
SMART |
|
efhand_Ca_insen
|
2382 |
2451 |
6.74e-32 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000095083
|
| SMART Domains |
Protein: ENSMUSP00000092697
Gene: ENSMUSG00000057738
| Domain | Start | End | E-Value | Type |
|---|
|
SPEC
|
47 |
146 |
2.1e-30 |
SMART |
|
SPEC
|
152 |
252 |
2.6e-35 |
SMART |
|
SPEC
|
258 |
358 |
4.93e-36 |
SMART |
|
SPEC
|
364 |
464 |
1.08e-27 |
SMART |
|
SPEC
|
470 |
570 |
9.01e-30 |
SMART |
|
SPEC
|
576 |
675 |
3.52e-32 |
SMART |
|
SPEC
|
681 |
781 |
2.15e-36 |
SMART |
|
SPEC
|
787 |
887 |
2.45e-40 |
SMART |
|
SPEC
|
893 |
1088 |
1.56e-24 |
SMART |
|
SH3
|
970 |
1025 |
8.24e-18 |
SMART |
|
SPEC
|
1094 |
1230 |
6.52e-27 |
SMART |
|
SPEC
|
1236 |
1336 |
1.44e-37 |
SMART |
|
SPEC
|
1342 |
1442 |
4.43e-29 |
SMART |
|
SPEC
|
1448 |
1548 |
7.54e-32 |
SMART |
|
SPEC
|
1554 |
1655 |
9.65e-30 |
SMART |
|
SPEC
|
1661 |
1761 |
2.32e-32 |
SMART |
|
SPEC
|
1767 |
1867 |
6.98e-36 |
SMART |
|
SPEC
|
1873 |
1973 |
1.53e-32 |
SMART |
|
SPEC
|
1979 |
2080 |
6.23e-24 |
SMART |
|
SPEC
|
2094 |
2194 |
2.08e-11 |
SMART |
|
SPEC
|
2208 |
2309 |
1.07e-4 |
SMART |
|
EFh
|
2327 |
2355 |
5.78e-7 |
SMART |
|
EFh
|
2370 |
2398 |
3.85e-3 |
SMART |
|
efhand_Ca_insen
|
2402 |
2471 |
6.74e-32 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000100225
|
| SMART Domains |
Protein: ENSMUSP00000097797
Gene: ENSMUSG00000057738
| Domain | Start | End | E-Value | Type |
|---|
|
SPEC
|
47 |
146 |
2.1e-30 |
SMART |
|
SPEC
|
152 |
252 |
2.6e-35 |
SMART |
|
SPEC
|
258 |
358 |
4.93e-36 |
SMART |
|
SPEC
|
364 |
464 |
1.08e-27 |
SMART |
|
SPEC
|
470 |
570 |
9.01e-30 |
SMART |
|
SPEC
|
576 |
675 |
3.52e-32 |
SMART |
|
SPEC
|
681 |
781 |
2.15e-36 |
SMART |
|
SPEC
|
787 |
887 |
2.45e-40 |
SMART |
|
SPEC
|
893 |
1088 |
1.56e-24 |
SMART |
|
SH3
|
970 |
1025 |
8.24e-18 |
SMART |
|
SPEC
|
1094 |
1230 |
6.52e-27 |
SMART |
|
SPEC
|
1236 |
1336 |
1.44e-37 |
SMART |
|
SPEC
|
1342 |
1442 |
4.43e-29 |
SMART |
|
SPEC
|
1448 |
1548 |
7.54e-32 |
SMART |
|
SPEC
|
1554 |
1660 |
2.06e-24 |
SMART |
|
SPEC
|
1666 |
1766 |
2.32e-32 |
SMART |
|
SPEC
|
1772 |
1872 |
6.98e-36 |
SMART |
|
SPEC
|
1878 |
1978 |
1.53e-32 |
SMART |
|
SPEC
|
1984 |
2085 |
6.23e-24 |
SMART |
|
SPEC
|
2099 |
2199 |
2.08e-11 |
SMART |
|
SPEC
|
2213 |
2314 |
1.07e-4 |
SMART |
|
EFh
|
2332 |
2360 |
5.78e-7 |
SMART |
|
EFh
|
2375 |
2403 |
3.85e-3 |
SMART |
|
efhand_Ca_insen
|
2407 |
2476 |
6.74e-32 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000113711
AA Change: A501S
PolyPhen 2
Score 0.817 (Sensitivity: 0.84; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000109340
Gene: ENSMUSG00000039715
AA Change: A501S
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
11 |
36 |
N/A |
INTRINSIC |
|
low complexity region
|
90 |
100 |
N/A |
INTRINSIC |
|
Blast:WD40
|
146 |
200 |
3e-28 |
BLAST |
|
WD40
|
207 |
247 |
2e-1 |
SMART |
|
WD40
|
256 |
300 |
3.42e1 |
SMART |
|
Blast:WD40
|
323 |
364 |
8e-10 |
BLAST |
|
WD40
|
382 |
422 |
1.66e-5 |
SMART |
|
WD40
|
425 |
465 |
3.09e-1 |
SMART |
|
WD40
|
470 |
512 |
4.18e-2 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000113717
|
| SMART Domains |
Protein: ENSMUSP00000109346
Gene: ENSMUSG00000057738
| Domain | Start | End | E-Value | Type |
|---|
|
SPEC
|
47 |
146 |
2.1e-30 |
SMART |
|
SPEC
|
152 |
252 |
2.6e-35 |
SMART |
|
SPEC
|
258 |
358 |
4.93e-36 |
SMART |
|
SPEC
|
364 |
464 |
1.08e-27 |
SMART |
|
SPEC
|
470 |
570 |
9.01e-30 |
SMART |
|
SPEC
|
576 |
675 |
3.52e-32 |
SMART |
|
SPEC
|
681 |
781 |
2.15e-36 |
SMART |
|
SPEC
|
787 |
887 |
2.45e-40 |
SMART |
|
SPEC
|
893 |
1068 |
1.18e-24 |
SMART |
|
SH3
|
970 |
1025 |
8.24e-18 |
SMART |
|
SPEC
|
1074 |
1210 |
6.52e-27 |
SMART |
|
SPEC
|
1216 |
1316 |
1.44e-37 |
SMART |
|
SPEC
|
1322 |
1422 |
4.43e-29 |
SMART |
|
SPEC
|
1428 |
1528 |
7.54e-32 |
SMART |
|
SPEC
|
1534 |
1640 |
2.06e-24 |
SMART |
|
SPEC
|
1646 |
1746 |
2.32e-32 |
SMART |
|
SPEC
|
1752 |
1852 |
6.98e-36 |
SMART |
|
SPEC
|
1858 |
1958 |
1.53e-32 |
SMART |
|
SPEC
|
1964 |
2065 |
6.23e-24 |
SMART |
|
SPEC
|
2079 |
2179 |
2.08e-11 |
SMART |
|
SPEC
|
2193 |
2294 |
1.07e-4 |
SMART |
|
EFh
|
2312 |
2340 |
5.78e-7 |
SMART |
|
EFh
|
2355 |
2383 |
3.85e-3 |
SMART |
|
efhand_Ca_insen
|
2387 |
2456 |
6.74e-32 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000113719
|
| SMART Domains |
Protein: ENSMUSP00000109348
Gene: ENSMUSG00000057738
| Domain | Start | End | E-Value | Type |
|---|
|
SPEC
|
47 |
146 |
2.1e-30 |
SMART |
|
SPEC
|
152 |
252 |
2.6e-35 |
SMART |
|
SPEC
|
258 |
358 |
4.93e-36 |
SMART |
|
SPEC
|
364 |
464 |
1.08e-27 |
SMART |
|
SPEC
|
470 |
570 |
9.01e-30 |
SMART |
|
SPEC
|
576 |
675 |
3.52e-32 |
SMART |
|
SPEC
|
681 |
781 |
2.15e-36 |
SMART |
|
SPEC
|
787 |
887 |
2.45e-40 |
SMART |
|
SPEC
|
893 |
1068 |
1.18e-24 |
SMART |
|
SH3
|
970 |
1025 |
8.24e-18 |
SMART |
|
SPEC
|
1074 |
1210 |
6.52e-27 |
SMART |
|
SPEC
|
1216 |
1316 |
1.44e-37 |
SMART |
|
SPEC
|
1322 |
1422 |
4.43e-29 |
SMART |
|
SPEC
|
1428 |
1528 |
7.54e-32 |
SMART |
|
SPEC
|
1534 |
1640 |
2.06e-24 |
SMART |
|
SPEC
|
1646 |
1746 |
2.32e-32 |
SMART |
|
SPEC
|
1752 |
1852 |
6.98e-36 |
SMART |
|
SPEC
|
1858 |
1958 |
1.53e-32 |
SMART |
|
SPEC
|
1964 |
2065 |
6.23e-24 |
SMART |
|
SPEC
|
2079 |
2179 |
2.08e-11 |
SMART |
|
SPEC
|
2193 |
2315 |
3.27e0 |
SMART |
|
EFh
|
2333 |
2361 |
5.78e-7 |
SMART |
|
EFh
|
2376 |
2404 |
3.85e-3 |
SMART |
|
efhand_Ca_insen
|
2408 |
2477 |
6.74e-32 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000129241
|
| SMART Domains |
Protein: ENSMUSP00000121116
Gene: ENSMUSG00000057738
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Spectrin
|
1 |
65 |
9.9e-10 |
PFAM |
|
SPEC
|
78 |
178 |
2.08e-11 |
SMART |
|
SPEC
|
192 |
314 |
3.27e0 |
SMART |
|
EFh
|
332 |
360 |
5.78e-7 |
SMART |
|
EFh
|
375 |
403 |
3.85e-3 |
SMART |
|
efhand_Ca_insen
|
407 |
476 |
6.74e-32 |
SMART |
|
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.7%
- 10x: 98.7%
- 20x: 93.2%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Defects in this gene are a cause of short-rib thoracic dysplasia 11 with or without polydactyly. [provided by RefSeq, Mar 2014]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 59 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 3425401B19Rik |
C |
T |
14: 32,382,266 (GRCm39) |
W1233* |
probably null |
Het |
| 4930590J08Rik |
A |
G |
6: 91,894,691 (GRCm39) |
I247V |
probably benign |
Het |
| 8030423J24Rik |
T |
A |
13: 71,032,077 (GRCm39) |
C50S |
unknown |
Het |
| Adam29 |
T |
G |
8: 56,324,585 (GRCm39) |
H623P |
probably benign |
Het |
| Adamts5 |
A |
G |
16: 85,696,203 (GRCm39) |
V318A |
probably damaging |
Het |
| Ano3 |
T |
C |
2: 110,614,058 (GRCm39) |
D215G |
possibly damaging |
Het |
| Ap3b2 |
A |
G |
7: 81,113,530 (GRCm39) |
I893T |
unknown |
Het |
| Apob |
G |
A |
12: 8,058,801 (GRCm39) |
A2428T |
probably benign |
Het |
| Armc3 |
T |
C |
2: 19,301,674 (GRCm39) |
V660A |
probably benign |
Het |
| Atf7 |
G |
T |
15: 102,471,769 (GRCm39) |
T42K |
probably damaging |
Het |
| Atg9a |
A |
T |
1: 75,164,366 (GRCm39) |
I160N |
probably damaging |
Het |
| Atp2b1 |
T |
C |
10: 98,832,786 (GRCm39) |
V429A |
possibly damaging |
Het |
| Bpifb3 |
A |
C |
2: 153,764,609 (GRCm39) |
H167P |
probably benign |
Het |
| Cacna1f |
G |
T |
X: 7,487,326 (GRCm39) |
E921D |
probably damaging |
Het |
| Ccdc57 |
T |
A |
11: 120,769,713 (GRCm39) |
L713F |
probably damaging |
Het |
| Chd1l |
C |
T |
3: 97,494,526 (GRCm39) |
E385K |
possibly damaging |
Het |
| Csmd1 |
C |
T |
8: 15,967,306 (GRCm39) |
V3186I |
probably benign |
Het |
| Dclre1c |
T |
A |
2: 3,448,185 (GRCm39) |
D349E |
probably benign |
Het |
| Dlg1 |
C |
T |
16: 31,661,620 (GRCm39) |
T657M |
possibly damaging |
Het |
| Dync2h1 |
T |
C |
9: 7,148,688 (GRCm39) |
I919V |
probably benign |
Het |
| Eml5 |
A |
G |
12: 98,758,773 (GRCm39) |
|
probably null |
Het |
| Epas1 |
C |
A |
17: 87,125,860 (GRCm39) |
S286* |
probably null |
Het |
| Fat1 |
G |
A |
8: 45,479,095 (GRCm39) |
V2714I |
possibly damaging |
Het |
| Fuca2 |
T |
C |
10: 13,390,545 (GRCm39) |
M447T |
probably benign |
Het |
| Gm10800 |
CAAGAAAACTGAAAATCAAAGAAAACTGAAAATCA |
CAAGAAAACTGAAAATCA |
2: 98,497,361 (GRCm39) |
|
probably null |
Het |
| Gm11110 |
A |
C |
17: 57,410,427 (GRCm39) |
C24G |
probably null |
Het |
| Gm6176 |
T |
A |
7: 21,750,593 (GRCm39) |
I113F |
probably benign |
Het |
| Gmcl1 |
G |
T |
6: 86,698,408 (GRCm39) |
A163E |
probably damaging |
Het |
| Gpat2 |
G |
T |
2: 127,275,777 (GRCm39) |
L518F |
probably damaging |
Het |
| Gpr137b |
T |
C |
13: 13,533,991 (GRCm39) |
Y355C |
|
Het |
| Hgsnat |
C |
T |
8: 26,458,440 (GRCm39) |
V195I |
probably benign |
Het |
| Hivep3 |
T |
A |
4: 119,955,583 (GRCm39) |
S1300T |
probably damaging |
Het |
| Hs3st2 |
A |
T |
7: 120,992,362 (GRCm39) |
H137L |
probably damaging |
Het |
| Iffo1 |
T |
C |
6: 125,122,781 (GRCm39) |
S188P |
possibly damaging |
Het |
| Itih1 |
T |
C |
14: 30,654,225 (GRCm39) |
D684G |
probably damaging |
Het |
| Lrba |
C |
A |
3: 86,235,012 (GRCm39) |
N852K |
probably damaging |
Het |
| Lrriq4 |
T |
C |
3: 30,709,930 (GRCm39) |
S425P |
possibly damaging |
Het |
| Mdn1 |
T |
A |
4: 32,674,003 (GRCm39) |
S562T |
possibly damaging |
Het |
| Mex3a |
T |
C |
3: 88,444,064 (GRCm39) |
V380A |
probably benign |
Het |
| Mgat4d |
A |
T |
8: 84,094,776 (GRCm39) |
N271I |
probably damaging |
Het |
| Mmp24 |
T |
A |
2: 155,649,345 (GRCm39) |
V254E |
possibly damaging |
Het |
| Muc16 |
T |
A |
9: 18,503,925 (GRCm39) |
R6455S |
possibly damaging |
Het |
| Npffr1 |
T |
A |
10: 61,459,128 (GRCm39) |
V127E |
probably damaging |
Het |
| Obox5 |
T |
A |
7: 15,492,541 (GRCm39) |
N165K |
probably damaging |
Het |
| Or10g3b |
G |
A |
14: 52,587,344 (GRCm39) |
T53M |
possibly damaging |
Het |
| Otulin |
A |
C |
15: 27,606,381 (GRCm39) |
V344G |
probably damaging |
Het |
| Pappa |
A |
G |
4: 65,180,229 (GRCm39) |
D1030G |
probably damaging |
Het |
| Pdzd2 |
G |
A |
15: 12,373,592 (GRCm39) |
S2181L |
probably benign |
Het |
| Ppp2r3c |
C |
A |
12: 55,344,634 (GRCm39) |
M111I |
probably benign |
Het |
| Prss37 |
T |
C |
6: 40,494,747 (GRCm39) |
T13A |
probably benign |
Het |
| Sfi1 |
TCGC |
TC |
11: 3,096,254 (GRCm39) |
|
probably null |
Het |
| Sgo2b |
T |
A |
8: 64,396,138 (GRCm39) |
K39N |
probably damaging |
Het |
| Sike1 |
T |
C |
3: 102,909,123 (GRCm39) |
*208Q |
probably null |
Het |
| Spire1 |
A |
G |
18: 67,652,391 (GRCm39) |
S229P |
probably damaging |
Het |
| Tmem132b |
A |
G |
5: 125,699,857 (GRCm39) |
I132V |
probably benign |
Het |
| Umodl1 |
T |
C |
17: 31,190,792 (GRCm39) |
V213A |
probably damaging |
Het |
| Washc1 |
C |
G |
17: 66,423,033 (GRCm39) |
Q116E |
probably benign |
Het |
| Zfp553 |
T |
A |
7: 126,836,093 (GRCm39) |
C549* |
probably null |
Het |
| Zfp9 |
G |
A |
6: 118,441,561 (GRCm39) |
P367L |
probably damaging |
Het |
|
| Other mutations in Dync2i2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL02007:Dync2i2
|
APN |
2 |
29,928,402 (GRCm39) |
missense |
probably benign |
0.11 |
|
IGL02165:Dync2i2
|
APN |
2 |
29,922,172 (GRCm39) |
missense |
probably benign |
|
|
IGL02600:Dync2i2
|
APN |
2 |
29,923,314 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
PIT1430001:Dync2i2
|
UTSW |
2 |
29,922,147 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0542:Dync2i2
|
UTSW |
2 |
29,921,837 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4065:Dync2i2
|
UTSW |
2 |
29,922,820 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4067:Dync2i2
|
UTSW |
2 |
29,922,820 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4750:Dync2i2
|
UTSW |
2 |
29,923,932 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4907:Dync2i2
|
UTSW |
2 |
29,922,472 (GRCm39) |
splice site |
probably null |
|
|
R5008:Dync2i2
|
UTSW |
2 |
29,922,781 (GRCm39) |
missense |
probably benign |
0.14 |
|
R5253:Dync2i2
|
UTSW |
2 |
29,922,375 (GRCm39) |
unclassified |
probably benign |
|
|
R6014:Dync2i2
|
UTSW |
2 |
29,921,763 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6456:Dync2i2
|
UTSW |
2 |
29,922,779 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6789:Dync2i2
|
UTSW |
2 |
29,923,284 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7024:Dync2i2
|
UTSW |
2 |
29,928,278 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R7319:Dync2i2
|
UTSW |
2 |
29,928,341 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7576:Dync2i2
|
UTSW |
2 |
29,938,790 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7640:Dync2i2
|
UTSW |
2 |
29,921,780 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8025:Dync2i2
|
UTSW |
2 |
29,938,730 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8273:Dync2i2
|
UTSW |
2 |
29,921,903 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8277:Dync2i2
|
UTSW |
2 |
29,923,886 (GRCm39) |
missense |
probably benign |
|
|
R8309:Dync2i2
|
UTSW |
2 |
29,922,201 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8724:Dync2i2
|
UTSW |
2 |
29,923,961 (GRCm39) |
missense |
probably benign |
0.11 |
|
R8732:Dync2i2
|
UTSW |
2 |
29,922,220 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R8837:Dync2i2
|
UTSW |
2 |
29,928,374 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9149:Dync2i2
|
UTSW |
2 |
29,923,953 (GRCm39) |
missense |
probably benign |
0.26 |
|
R9190:Dync2i2
|
UTSW |
2 |
29,922,211 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9557:Dync2i2
|
UTSW |
2 |
29,922,534 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
| Predicted Primers |
PCR Primer
(F):5'- CACAGCCATCCTGAAGCATG -3'
(R):5'- TGAAGATGGTGGCTCTCTGC -3'
Sequencing Primer
(F):5'- GGGCATCAGATCTCATTACGG -3'
(R):5'- CTGTGGTTTCTATGTGTTCTGAAC -3'
|
| Posted On |
2020-06-30 |
Incidental Mutation