Incidental Mutation 'R8117:Cntn5'
| ID |
631274 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Cntn5
|
| Ensembl Gene |
ENSMUSG00000039488 |
| Gene Name |
contactin 5 |
| Synonyms |
A830025P08Rik, 6720426O10Rik, NB-2, LOC244683 |
| MMRRC Submission |
067546-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R8117 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
9 |
| Chromosomal Location |
9660896-10904780 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 9673955 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Proline
at position 716
(S716P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000124214
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000074133]
[ENSMUST00000160216]
[ENSMUST00000162484]
[ENSMUST00000179049]
|
| AlphaFold |
P68500 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000074133
AA Change: S921P
PolyPhen 2
Score 0.328 (Sensitivity: 0.90; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000073769
Gene: ENSMUSG00000039488
AA Change: S921P
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
23 |
N/A |
INTRINSIC |
|
IGc2
|
113 |
179 |
1.11e-10 |
SMART |
|
IG
|
201 |
289 |
4.82e-6 |
SMART |
|
IGc2
|
312 |
375 |
1.4e-16 |
SMART |
|
IGc2
|
401 |
464 |
8.97e-15 |
SMART |
|
IGc2
|
493 |
557 |
4.96e-8 |
SMART |
|
IG
|
577 |
667 |
2.13e-7 |
SMART |
|
FN3
|
670 |
756 |
1.01e-11 |
SMART |
|
FN3
|
773 |
859 |
9.19e-1 |
SMART |
|
FN3
|
875 |
958 |
3.99e-10 |
SMART |
|
FN3
|
974 |
1053 |
1.68e-3 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000160216
AA Change: S921P
PolyPhen 2
Score 0.328 (Sensitivity: 0.90; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000124327
Gene: ENSMUSG00000039488
AA Change: S921P
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
23 |
N/A |
INTRINSIC |
|
IGc2
|
113 |
179 |
1.11e-10 |
SMART |
|
IG
|
201 |
289 |
4.82e-6 |
SMART |
|
IGc2
|
312 |
375 |
1.4e-16 |
SMART |
|
IGc2
|
401 |
464 |
8.97e-15 |
SMART |
|
IGc2
|
493 |
557 |
4.96e-8 |
SMART |
|
IG
|
577 |
667 |
2.13e-7 |
SMART |
|
FN3
|
670 |
756 |
1.01e-11 |
SMART |
|
FN3
|
773 |
859 |
9.19e-1 |
SMART |
|
FN3
|
875 |
958 |
3.99e-10 |
SMART |
|
FN3
|
974 |
1053 |
1.68e-3 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000162484
AA Change: S716P
PolyPhen 2
Score 0.328 (Sensitivity: 0.90; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000124214
Gene: ENSMUSG00000039488
AA Change: S716P
| Domain | Start | End | E-Value | Type |
|---|
|
IG_like
|
10 |
84 |
1.12e2 |
SMART |
|
IGc2
|
107 |
170 |
1.4e-16 |
SMART |
|
IGc2
|
196 |
259 |
8.97e-15 |
SMART |
|
IGc2
|
288 |
352 |
4.96e-8 |
SMART |
|
IG
|
372 |
462 |
2.13e-7 |
SMART |
|
FN3
|
465 |
551 |
1.01e-11 |
SMART |
|
FN3
|
568 |
654 |
9.19e-1 |
SMART |
|
FN3
|
670 |
753 |
3.99e-10 |
SMART |
|
FN3
|
769 |
848 |
1.68e-3 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000179049
AA Change: S716P
PolyPhen 2
Score 0.328 (Sensitivity: 0.90; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000135903
Gene: ENSMUSG00000039488
AA Change: S716P
| Domain | Start | End | E-Value | Type |
|---|
|
IG_like
|
10 |
84 |
1.12e2 |
SMART |
|
IGc2
|
107 |
170 |
1.4e-16 |
SMART |
|
IGc2
|
196 |
259 |
8.97e-15 |
SMART |
|
IGc2
|
288 |
352 |
4.96e-8 |
SMART |
|
IG
|
372 |
462 |
2.13e-7 |
SMART |
|
FN3
|
465 |
551 |
1.01e-11 |
SMART |
|
FN3
|
568 |
654 |
9.19e-1 |
SMART |
|
FN3
|
670 |
753 |
3.99e-10 |
SMART |
|
FN3
|
769 |
848 |
1.68e-3 |
SMART |
|
| Coding Region Coverage |
- 1x: 99.8%
- 3x: 99.5%
- 10x: 98.5%
- 20x: 94.4%
|
| Validation Efficiency |
99% (73/74) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a member of the immunoglobulin superfamily, and contactin family, which mediate cell surface interactions during nervous system development. This protein is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
PHENOTYPE: Homozygous null mice are viable, fertile, and less susceptible to audiogenic seizures. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 71 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2010315B03Rik |
T |
C |
9: 124,058,078 (GRCm39) |
T14A |
|
Het |
| 2610008E11Rik |
T |
C |
10: 78,930,289 (GRCm39) |
N42D |
probably benign |
Het |
| Ajm1 |
A |
G |
2: 25,469,246 (GRCm39) |
F222L |
probably benign |
Het |
| Ankrd54 |
T |
A |
15: 78,939,641 (GRCm39) |
M183L |
|
Het |
| Apob |
G |
A |
12: 8,056,435 (GRCm39) |
G1639D |
probably damaging |
Het |
| B3gat2 |
A |
G |
1: 23,884,061 (GRCm39) |
T283A |
probably benign |
Het |
| Bmpr2 |
T |
G |
1: 59,886,252 (GRCm39) |
S296R |
probably damaging |
Het |
| Cand1 |
G |
A |
10: 119,042,721 (GRCm39) |
T1123I |
probably damaging |
Het |
| Cc2d2a |
T |
C |
5: 43,869,781 (GRCm39) |
F943S |
probably damaging |
Het |
| Ccdc40 |
T |
C |
11: 119,144,211 (GRCm39) |
I912T |
probably benign |
Het |
| Cdkn2d |
G |
A |
9: 21,200,447 (GRCm39) |
S108L |
probably benign |
Het |
| Cep295 |
G |
A |
9: 15,245,660 (GRCm39) |
T932I |
probably damaging |
Het |
| Col18a1 |
T |
C |
10: 76,895,808 (GRCm39) |
E903G |
probably benign |
Het |
| Ctrc |
T |
A |
4: 141,565,972 (GRCm39) |
I229F |
probably damaging |
Het |
| Cyb561d2 |
C |
T |
9: 107,418,771 (GRCm39) |
A18T |
probably benign |
Het |
| Dnajb4 |
T |
A |
3: 151,899,089 (GRCm39) |
K46* |
probably null |
Het |
| Dsc2 |
C |
T |
18: 20,165,331 (GRCm39) |
G881R |
possibly damaging |
Het |
| Dsg1c |
C |
T |
18: 20,410,016 (GRCm39) |
H495Y |
probably benign |
Het |
| Eif2b3 |
A |
G |
4: 116,879,414 (GRCm39) |
D18G |
probably damaging |
Het |
| Enam |
A |
T |
5: 88,651,385 (GRCm39) |
I965L |
probably benign |
Het |
| Fhod3 |
T |
A |
18: 25,248,910 (GRCm39) |
I1363K |
probably damaging |
Het |
| Fras1 |
A |
G |
5: 96,855,245 (GRCm39) |
Y1918C |
probably damaging |
Het |
| Fsip2 |
T |
A |
2: 82,823,296 (GRCm39) |
I6343N |
possibly damaging |
Het |
| Gpr45 |
G |
C |
1: 43,072,475 (GRCm39) |
V373L |
probably damaging |
Het |
| Hdac2 |
G |
T |
10: 36,873,966 (GRCm39) |
Q365H |
probably damaging |
Het |
| Hspa12b |
A |
G |
2: 130,980,389 (GRCm39) |
T103A |
possibly damaging |
Het |
| Ifrd1 |
A |
T |
12: 40,262,350 (GRCm39) |
S287T |
probably benign |
Het |
| Igkv6-15 |
G |
A |
6: 70,383,622 (GRCm39) |
P60S |
possibly damaging |
Het |
| Ippk |
C |
T |
13: 49,599,818 (GRCm39) |
P226S |
|
Het |
| Kctd19 |
T |
A |
8: 106,122,069 (GRCm39) |
D109V |
unknown |
Het |
| Matn4 |
G |
A |
2: 164,234,851 (GRCm39) |
S540L |
probably damaging |
Het |
| Matn4 |
T |
C |
2: 164,241,682 (GRCm39) |
K248E |
probably benign |
Het |
| Muc16 |
G |
A |
9: 18,420,206 (GRCm39) |
Q97* |
probably null |
Het |
| Mup18 |
A |
G |
4: 61,592,238 (GRCm39) |
C9R |
unknown |
Het |
| Myh1 |
A |
G |
11: 67,113,031 (GRCm39) |
K1845R |
probably damaging |
Het |
| Mysm1 |
G |
A |
4: 94,848,627 (GRCm39) |
R469* |
probably null |
Het |
| Naip1 |
T |
C |
13: 100,563,509 (GRCm39) |
D552G |
possibly damaging |
Het |
| Nrcam |
A |
G |
12: 44,618,371 (GRCm39) |
D787G |
probably benign |
Het |
| Nrcam |
G |
A |
12: 44,645,365 (GRCm39) |
V1256I |
probably damaging |
Het |
| Obscn |
G |
T |
11: 58,932,980 (GRCm39) |
H4799N |
possibly damaging |
Het |
| Or1f12 |
T |
C |
13: 21,722,122 (GRCm39) |
K3E |
probably benign |
Het |
| Or4p4 |
A |
G |
2: 88,482,729 (GRCm39) |
K78E |
probably damaging |
Het |
| Or52e18 |
T |
C |
7: 104,609,356 (GRCm39) |
I194M |
probably damaging |
Het |
| Or7g22 |
A |
G |
9: 19,048,353 (GRCm39) |
I21M |
probably benign |
Het |
| Pcdhgb5 |
T |
C |
18: 37,866,302 (GRCm39) |
F699S |
probably damaging |
Het |
| Phtf2 |
T |
C |
5: 21,007,038 (GRCm39) |
E175G |
probably benign |
Het |
| Pira1 |
G |
A |
7: 3,740,075 (GRCm39) |
T340I |
probably damaging |
Het |
| Ppp2r5c |
A |
G |
12: 110,517,519 (GRCm39) |
H218R |
possibly damaging |
Het |
| Ptgs2 |
A |
G |
1: 149,979,785 (GRCm39) |
R297G |
probably damaging |
Het |
| Rapgef3 |
A |
T |
15: 97,648,747 (GRCm39) |
D619E |
probably benign |
Het |
| Ric1 |
G |
A |
19: 29,552,191 (GRCm39) |
V321I |
probably benign |
Het |
| Ripor1 |
T |
C |
8: 106,344,105 (GRCm39) |
V413A |
probably damaging |
Het |
| Rsf1 |
G |
T |
7: 97,288,464 (GRCm39) |
|
probably null |
Het |
| Sccpdh |
A |
G |
1: 179,504,017 (GRCm39) |
D122G |
probably damaging |
Het |
| Sec16a |
A |
T |
2: 26,331,441 (GRCm39) |
H191Q |
probably benign |
Het |
| Slco1a5 |
G |
T |
6: 142,208,418 (GRCm39) |
N124K |
probably damaging |
Het |
| Snrnp200 |
A |
G |
2: 127,071,051 (GRCm39) |
T1111A |
probably benign |
Het |
| Stard9 |
G |
A |
2: 120,534,911 (GRCm39) |
G3723S |
probably benign |
Het |
| Tanc2 |
T |
A |
11: 105,725,988 (GRCm39) |
V384E |
probably damaging |
Het |
| Tbrg1 |
A |
G |
9: 37,568,296 (GRCm39) |
F49L |
possibly damaging |
Het |
| Tecta |
A |
G |
9: 42,288,927 (GRCm39) |
F546S |
probably damaging |
Het |
| Tmem132c |
A |
G |
5: 127,437,176 (GRCm39) |
R222G |
probably benign |
Het |
| Trub2 |
C |
T |
2: 29,668,739 (GRCm39) |
|
probably null |
Het |
| Tti1 |
G |
T |
2: 157,849,418 (GRCm39) |
P607Q |
probably damaging |
Het |
| Vmn1r62 |
T |
A |
7: 5,678,726 (GRCm39) |
F136I |
possibly damaging |
Het |
| Vmn2r111 |
T |
A |
17: 22,790,469 (GRCm39) |
H179L |
probably benign |
Het |
| Wdfy4 |
A |
T |
14: 32,699,063 (GRCm39) |
C2703* |
probably null |
Het |
| Wdfy4 |
G |
A |
14: 32,826,072 (GRCm39) |
P1193L |
|
Het |
| Wipf3 |
A |
G |
6: 54,460,816 (GRCm39) |
K88R |
probably benign |
Het |
| Zfp641 |
C |
T |
15: 98,186,856 (GRCm39) |
G256R |
probably damaging |
Het |
| Zfp993 |
T |
A |
4: 146,741,972 (GRCm39) |
C99S |
probably benign |
Het |
|
| Other mutations in Cntn5 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00742:Cntn5
|
APN |
9 |
9,976,302 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01118:Cntn5
|
APN |
9 |
9,831,565 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL01328:Cntn5
|
APN |
9 |
9,781,773 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01445:Cntn5
|
APN |
9 |
9,693,489 (GRCm39) |
splice site |
probably benign |
|
|
IGL01505:Cntn5
|
APN |
9 |
9,706,092 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01556:Cntn5
|
APN |
9 |
9,673,913 (GRCm39) |
missense |
probably benign |
|
|
IGL01804:Cntn5
|
APN |
9 |
9,831,542 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02173:Cntn5
|
APN |
9 |
9,748,401 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02250:Cntn5
|
APN |
9 |
10,145,336 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02366:Cntn5
|
APN |
9 |
9,984,060 (GRCm39) |
splice site |
probably benign |
|
|
IGL02565:Cntn5
|
APN |
9 |
10,145,343 (GRCm39) |
nonsense |
probably null |
|
|
IGL02593:Cntn5
|
APN |
9 |
9,833,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02743:Cntn5
|
APN |
9 |
9,984,115 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02976:Cntn5
|
APN |
9 |
10,419,104 (GRCm39) |
unclassified |
probably benign |
|
|
IGL03103:Cntn5
|
APN |
9 |
9,972,817 (GRCm39) |
splice site |
probably benign |
|
|
IGL03114:Cntn5
|
APN |
9 |
9,748,457 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03156:Cntn5
|
APN |
9 |
9,673,882 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02802:Cntn5
|
UTSW |
9 |
10,048,683 (GRCm39) |
splice site |
probably null |
|
|
R0243:Cntn5
|
UTSW |
9 |
9,781,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0385:Cntn5
|
UTSW |
9 |
9,972,875 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0541:Cntn5
|
UTSW |
9 |
9,673,407 (GRCm39) |
splice site |
probably benign |
|
|
R0827:Cntn5
|
UTSW |
9 |
9,666,943 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R1029:Cntn5
|
UTSW |
9 |
9,831,577 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1440:Cntn5
|
UTSW |
9 |
10,145,344 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1463:Cntn5
|
UTSW |
9 |
9,673,801 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1536:Cntn5
|
UTSW |
9 |
9,976,321 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R1746:Cntn5
|
UTSW |
9 |
9,831,577 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1761:Cntn5
|
UTSW |
9 |
10,172,059 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1764:Cntn5
|
UTSW |
9 |
9,673,988 (GRCm39) |
missense |
probably benign |
|
|
R1859:Cntn5
|
UTSW |
9 |
9,972,839 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1888:Cntn5
|
UTSW |
9 |
9,984,082 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1888:Cntn5
|
UTSW |
9 |
9,984,082 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1950:Cntn5
|
UTSW |
9 |
9,781,774 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2143:Cntn5
|
UTSW |
9 |
9,748,420 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2145:Cntn5
|
UTSW |
9 |
9,748,420 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2437:Cntn5
|
UTSW |
9 |
10,048,758 (GRCm39) |
nonsense |
probably null |
|
|
R2440:Cntn5
|
UTSW |
9 |
10,171,960 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R2504:Cntn5
|
UTSW |
9 |
10,172,126 (GRCm39) |
missense |
probably benign |
|
|
R3054:Cntn5
|
UTSW |
9 |
10,419,076 (GRCm39) |
missense |
probably benign |
0.30 |
|
R3056:Cntn5
|
UTSW |
9 |
10,419,076 (GRCm39) |
missense |
probably benign |
0.30 |
|
R3804:Cntn5
|
UTSW |
9 |
9,781,668 (GRCm39) |
splice site |
probably benign |
|
|
R4164:Cntn5
|
UTSW |
9 |
9,781,681 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4444:Cntn5
|
UTSW |
9 |
9,704,947 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4472:Cntn5
|
UTSW |
9 |
10,048,776 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4576:Cntn5
|
UTSW |
9 |
9,673,297 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4624:Cntn5
|
UTSW |
9 |
9,704,809 (GRCm39) |
nonsense |
probably null |
|
|
R4652:Cntn5
|
UTSW |
9 |
9,704,917 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R4664:Cntn5
|
UTSW |
9 |
10,144,214 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R4679:Cntn5
|
UTSW |
9 |
9,970,536 (GRCm39) |
missense |
probably benign |
0.09 |
|
R4829:Cntn5
|
UTSW |
9 |
9,976,288 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4929:Cntn5
|
UTSW |
9 |
9,976,400 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R5211:Cntn5
|
UTSW |
9 |
9,704,894 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R5406:Cntn5
|
UTSW |
9 |
9,833,465 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5468:Cntn5
|
UTSW |
9 |
9,743,633 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5584:Cntn5
|
UTSW |
9 |
9,661,457 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R5688:Cntn5
|
UTSW |
9 |
9,748,427 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5762:Cntn5
|
UTSW |
9 |
9,748,394 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6141:Cntn5
|
UTSW |
9 |
10,144,162 (GRCm39) |
missense |
probably benign |
|
|
R6147:Cntn5
|
UTSW |
9 |
10,012,894 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6325:Cntn5
|
UTSW |
9 |
10,144,328 (GRCm39) |
splice site |
probably null |
|
|
R6377:Cntn5
|
UTSW |
9 |
9,743,657 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6774:Cntn5
|
UTSW |
9 |
10,144,222 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7117:Cntn5
|
UTSW |
9 |
10,904,704 (GRCm39) |
start gained |
probably benign |
|
|
R7252:Cntn5
|
UTSW |
9 |
9,831,640 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7363:Cntn5
|
UTSW |
9 |
10,172,021 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7401:Cntn5
|
UTSW |
9 |
9,833,466 (GRCm39) |
missense |
probably benign |
0.13 |
|
R7488:Cntn5
|
UTSW |
9 |
9,970,570 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7548:Cntn5
|
UTSW |
9 |
9,673,415 (GRCm39) |
splice site |
probably null |
|
|
R7662:Cntn5
|
UTSW |
9 |
9,661,390 (GRCm39) |
missense |
probably benign |
0.17 |
|
R7718:Cntn5
|
UTSW |
9 |
9,984,133 (GRCm39) |
missense |
probably benign |
|
|
R7719:Cntn5
|
UTSW |
9 |
9,704,903 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7788:Cntn5
|
UTSW |
9 |
9,704,934 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7864:Cntn5
|
UTSW |
9 |
9,984,182 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7937:Cntn5
|
UTSW |
9 |
9,748,450 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8159:Cntn5
|
UTSW |
9 |
10,145,386 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R8349:Cntn5
|
UTSW |
9 |
9,666,840 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8449:Cntn5
|
UTSW |
9 |
9,666,840 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8779:Cntn5
|
UTSW |
9 |
10,171,920 (GRCm39) |
missense |
probably benign |
|
|
R8789:Cntn5
|
UTSW |
9 |
9,673,292 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8985:Cntn5
|
UTSW |
9 |
10,171,960 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9370:Cntn5
|
UTSW |
9 |
9,833,520 (GRCm39) |
missense |
probably benign |
0.19 |
|
R9382:Cntn5
|
UTSW |
9 |
9,673,817 (GRCm39) |
missense |
probably benign |
|
|
R9781:Cntn5
|
UTSW |
9 |
10,048,686 (GRCm39) |
critical splice donor site |
probably null |
|
|
Z1177:Cntn5
|
UTSW |
9 |
10,090,241 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Cntn5
|
UTSW |
9 |
9,673,967 (GRCm39) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- AATCCCAGGTCACTTACGGTG -3'
(R):5'- GAAATCAAGGCAGTTTGGGC -3'
Sequencing Primer
(F):5'- AGGTCACTTACGGTGCCTCTTTG -3'
(R):5'- CAGAGGCAATTTCTTTCAGGG -3'
|
| Posted On |
2020-06-30 |
Incidental Mutation