Incidental Mutation 'R8167:Kat6b'
| ID |
633867 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Kat6b
|
| Ensembl Gene |
ENSMUSG00000021767 |
| Gene Name |
K(lysine) acetyltransferase 6B |
| Synonyms |
monocytic leukemia, Myst4, B130044K16Rik, Morf, qkf, querkopf |
| MMRRC Submission |
067593-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.912)
|
| Stock # |
R8167 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
14 |
| Chromosomal Location |
21549284-21722546 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 21719953 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Isoleucine
at position 1435
(T1435I)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000138511
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000069648]
[ENSMUST00000112458]
[ENSMUST00000182405]
[ENSMUST00000182855]
[ENSMUST00000182964]
|
| AlphaFold |
Q8BRB7 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000069648
AA Change: T1544I
PolyPhen 2
Score 0.946 (Sensitivity: 0.80; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000066693
Gene: ENSMUSG00000021767
AA Change: T1544I
| Domain | Start | End | E-Value | Type |
|---|
|
H15
|
94 |
171 |
1.7e-12 |
SMART |
|
low complexity region
|
189 |
203 |
N/A |
INTRINSIC |
|
PHD
|
216 |
271 |
6.6e-5 |
SMART |
|
PHD
|
272 |
319 |
5.56e-12 |
SMART |
|
low complexity region
|
386 |
398 |
N/A |
INTRINSIC |
|
low complexity region
|
411 |
425 |
N/A |
INTRINSIC |
|
Blast:PHD
|
483 |
573 |
3e-51 |
BLAST |
|
Pfam:MOZ_SAS
|
594 |
772 |
4.5e-85 |
PFAM |
|
coiled coil region
|
811 |
845 |
N/A |
INTRINSIC |
|
coiled coil region
|
875 |
913 |
N/A |
INTRINSIC |
|
low complexity region
|
926 |
943 |
N/A |
INTRINSIC |
|
low complexity region
|
946 |
959 |
N/A |
INTRINSIC |
|
low complexity region
|
1153 |
1175 |
N/A |
INTRINSIC |
|
low complexity region
|
1207 |
1237 |
N/A |
INTRINSIC |
|
low complexity region
|
1391 |
1410 |
N/A |
INTRINSIC |
|
low complexity region
|
1450 |
1464 |
N/A |
INTRINSIC |
|
low complexity region
|
1490 |
1517 |
N/A |
INTRINSIC |
|
low complexity region
|
1676 |
1695 |
N/A |
INTRINSIC |
|
low complexity region
|
1811 |
1832 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000112458
|
| SMART Domains |
Protein: ENSMUSP00000108077
Gene: ENSMUSG00000021767
| Domain | Start | End | E-Value | Type |
|---|
|
H15
|
94 |
159 |
3.4e-1 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000182405
AA Change: T1435I
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000138377
Gene: ENSMUSG00000021767
AA Change: T1435I
| Domain | Start | End | E-Value | Type |
|---|
|
H15
|
94 |
171 |
1.7e-12 |
SMART |
|
low complexity region
|
189 |
203 |
N/A |
INTRINSIC |
|
PHD
|
216 |
271 |
6.6e-5 |
SMART |
|
PHD
|
272 |
319 |
5.56e-12 |
SMART |
|
Pfam:MOZ_SAS
|
482 |
669 |
1.3e-89 |
PFAM |
|
coiled coil region
|
702 |
736 |
N/A |
INTRINSIC |
|
coiled coil region
|
766 |
804 |
N/A |
INTRINSIC |
|
low complexity region
|
817 |
834 |
N/A |
INTRINSIC |
|
low complexity region
|
837 |
850 |
N/A |
INTRINSIC |
|
low complexity region
|
1044 |
1066 |
N/A |
INTRINSIC |
|
low complexity region
|
1098 |
1128 |
N/A |
INTRINSIC |
|
low complexity region
|
1282 |
1301 |
N/A |
INTRINSIC |
|
low complexity region
|
1341 |
1355 |
N/A |
INTRINSIC |
|
low complexity region
|
1381 |
1408 |
N/A |
INTRINSIC |
|
low complexity region
|
1567 |
1586 |
N/A |
INTRINSIC |
|
low complexity region
|
1702 |
1723 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000182855
AA Change: T1435I
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000138511
Gene: ENSMUSG00000021767
AA Change: T1435I
| Domain | Start | End | E-Value | Type |
|---|
|
H15
|
94 |
171 |
1.7e-12 |
SMART |
|
low complexity region
|
189 |
203 |
N/A |
INTRINSIC |
|
PHD
|
216 |
271 |
6.6e-5 |
SMART |
|
PHD
|
272 |
319 |
5.56e-12 |
SMART |
|
Pfam:MOZ_SAS
|
482 |
669 |
1.3e-89 |
PFAM |
|
coiled coil region
|
702 |
736 |
N/A |
INTRINSIC |
|
coiled coil region
|
766 |
804 |
N/A |
INTRINSIC |
|
low complexity region
|
817 |
834 |
N/A |
INTRINSIC |
|
low complexity region
|
837 |
850 |
N/A |
INTRINSIC |
|
low complexity region
|
1044 |
1066 |
N/A |
INTRINSIC |
|
low complexity region
|
1098 |
1128 |
N/A |
INTRINSIC |
|
low complexity region
|
1282 |
1301 |
N/A |
INTRINSIC |
|
low complexity region
|
1341 |
1355 |
N/A |
INTRINSIC |
|
low complexity region
|
1381 |
1408 |
N/A |
INTRINSIC |
|
low complexity region
|
1567 |
1586 |
N/A |
INTRINSIC |
|
low complexity region
|
1702 |
1723 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000182964
AA Change: T1544I
PolyPhen 2
Score 0.946 (Sensitivity: 0.80; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000138421
Gene: ENSMUSG00000021767
AA Change: T1544I
| Domain | Start | End | E-Value | Type |
|---|
|
H15
|
94 |
171 |
1.7e-12 |
SMART |
|
low complexity region
|
189 |
203 |
N/A |
INTRINSIC |
|
PHD
|
216 |
271 |
6.6e-5 |
SMART |
|
PHD
|
272 |
319 |
5.56e-12 |
SMART |
|
low complexity region
|
386 |
398 |
N/A |
INTRINSIC |
|
low complexity region
|
411 |
425 |
N/A |
INTRINSIC |
|
Blast:PHD
|
483 |
573 |
3e-51 |
BLAST |
|
Pfam:MOZ_SAS
|
591 |
778 |
1.4e-89 |
PFAM |
|
coiled coil region
|
811 |
845 |
N/A |
INTRINSIC |
|
coiled coil region
|
875 |
913 |
N/A |
INTRINSIC |
|
low complexity region
|
926 |
943 |
N/A |
INTRINSIC |
|
low complexity region
|
946 |
959 |
N/A |
INTRINSIC |
|
low complexity region
|
1153 |
1175 |
N/A |
INTRINSIC |
|
low complexity region
|
1207 |
1237 |
N/A |
INTRINSIC |
|
low complexity region
|
1391 |
1410 |
N/A |
INTRINSIC |
|
low complexity region
|
1450 |
1464 |
N/A |
INTRINSIC |
|
low complexity region
|
1490 |
1517 |
N/A |
INTRINSIC |
|
low complexity region
|
1676 |
1695 |
N/A |
INTRINSIC |
|
low complexity region
|
1811 |
1832 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.5%
- 20x: 98.5%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Reduced expression of this gene results in developmental defects of the skeleton and brain, particularly the cerebral cortex. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 75 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4931406B18Rik |
T |
A |
7: 43,147,288 (GRCm39) |
I315F |
possibly damaging |
Het |
| Aadacl2fm3 |
T |
A |
3: 59,784,632 (GRCm39) |
D368E |
probably benign |
Het |
| Acin1 |
G |
A |
14: 54,902,337 (GRCm39) |
T485I |
probably benign |
Het |
| Adamts2 |
A |
T |
11: 50,670,541 (GRCm39) |
I552F |
probably damaging |
Het |
| Anapc11 |
T |
A |
11: 120,490,112 (GRCm39) |
N9K |
probably benign |
Het |
| Arhgef18 |
A |
T |
8: 3,403,636 (GRCm39) |
|
probably benign |
Het |
| Atp9b |
T |
C |
18: 80,890,398 (GRCm39) |
T314A |
|
Het |
| Birc6 |
T |
A |
17: 74,950,389 (GRCm39) |
I3214N |
probably damaging |
Het |
| Catsperb |
A |
G |
12: 101,557,714 (GRCm39) |
I762V |
probably benign |
Het |
| Cblb |
T |
A |
16: 51,986,365 (GRCm39) |
M536K |
probably benign |
Het |
| Ccdc85c |
C |
A |
12: 108,240,759 (GRCm39) |
A212S |
unknown |
Het |
| Cdh23 |
T |
A |
10: 60,150,162 (GRCm39) |
D2561V |
probably benign |
Het |
| Cdh23 |
T |
A |
10: 60,173,472 (GRCm39) |
Y1672F |
probably damaging |
Het |
| Cep83 |
T |
C |
10: 94,564,579 (GRCm39) |
S173P |
possibly damaging |
Het |
| Ctc1 |
C |
T |
11: 68,918,584 (GRCm39) |
P530S |
probably damaging |
Het |
| D630045J12Rik |
A |
G |
6: 38,167,484 (GRCm39) |
|
probably null |
Het |
| Dnah7b |
A |
T |
1: 46,292,671 (GRCm39) |
I3019F |
possibly damaging |
Het |
| Dsc1 |
T |
C |
18: 20,230,258 (GRCm39) |
D349G |
probably damaging |
Het |
| Ehd2 |
C |
G |
7: 15,697,917 (GRCm39) |
G107R |
probably damaging |
Het |
| Epha3 |
A |
T |
16: 63,388,804 (GRCm39) |
W816R |
probably damaging |
Het |
| Fam135b |
T |
A |
15: 71,404,840 (GRCm39) |
S69C |
probably null |
Het |
| Fbxo43 |
A |
G |
15: 36,151,917 (GRCm39) |
F600S |
probably damaging |
Het |
| Flnc |
A |
T |
6: 29,455,921 (GRCm39) |
D2117V |
probably damaging |
Het |
| Gas2l3 |
T |
A |
10: 89,262,342 (GRCm39) |
T127S |
probably damaging |
Het |
| Gli3 |
T |
G |
13: 15,900,228 (GRCm39) |
L1205R |
probably benign |
Het |
| Gm17093 |
A |
T |
14: 44,758,139 (GRCm39) |
I107F |
|
Het |
| Gm7298 |
T |
A |
6: 121,761,414 (GRCm39) |
C1323* |
probably null |
Het |
| H2-D1 |
A |
G |
17: 35,485,741 (GRCm39) |
T89A |
|
Het |
| Hira |
T |
G |
16: 18,715,259 (GRCm39) |
D52E |
probably benign |
Het |
| Ighv6-6 |
G |
C |
12: 114,398,525 (GRCm39) |
Y80* |
probably null |
Het |
| Kcna1 |
C |
A |
6: 126,620,443 (GRCm39) |
|
probably benign |
Het |
| Kif24 |
C |
A |
4: 41,392,957 (GRCm39) |
R1284L |
possibly damaging |
Het |
| Kremen2 |
A |
C |
17: 23,962,314 (GRCm39) |
C173G |
probably damaging |
Het |
| Krtap24-1 |
G |
C |
16: 88,408,707 (GRCm39) |
Q140E |
probably benign |
Het |
| Lrrc66 |
C |
A |
5: 73,786,952 (GRCm39) |
G133* |
probably null |
Het |
| Mast1 |
C |
A |
8: 85,647,987 (GRCm39) |
R498L |
probably damaging |
Het |
| Myom3 |
T |
C |
4: 135,534,504 (GRCm39) |
I1231T |
possibly damaging |
Het |
| Nid2 |
G |
A |
14: 19,860,131 (GRCm39) |
V1350I |
possibly damaging |
Het |
| Or4f59 |
A |
T |
2: 111,872,789 (GRCm39) |
V196D |
possibly damaging |
Het |
| Or8j3c |
A |
G |
2: 86,253,484 (GRCm39) |
C179R |
probably damaging |
Het |
| Or9r3 |
T |
C |
10: 129,948,350 (GRCm39) |
Q103R |
probably damaging |
Het |
| Pde4a |
A |
G |
9: 21,117,469 (GRCm39) |
D577G |
possibly damaging |
Het |
| Pde4d |
T |
A |
13: 109,578,855 (GRCm39) |
N36K |
probably benign |
Het |
| Plekhg1 |
A |
T |
10: 3,907,452 (GRCm39) |
S845C |
|
Het |
| Plekhg1 |
G |
A |
10: 3,907,453 (GRCm39) |
S845N |
|
Het |
| Plod1 |
C |
T |
4: 148,004,658 (GRCm39) |
D481N |
probably damaging |
Het |
| Plxna4 |
T |
A |
6: 32,493,981 (GRCm39) |
M212L |
probably damaging |
Het |
| Ppip5k1 |
C |
A |
2: 121,173,282 (GRCm39) |
E464* |
probably null |
Het |
| Raph1 |
T |
A |
1: 60,529,270 (GRCm39) |
M664L |
unknown |
Het |
| Rbm11 |
A |
C |
16: 75,395,673 (GRCm39) |
M115L |
probably benign |
Het |
| Rerg |
T |
C |
6: 137,034,869 (GRCm39) |
H45R |
possibly damaging |
Het |
| Rnf43 |
A |
G |
11: 87,618,232 (GRCm39) |
E47G |
probably benign |
Het |
| Rsph1 |
A |
G |
17: 31,496,260 (GRCm39) |
|
probably benign |
Het |
| Safb |
A |
G |
17: 56,892,286 (GRCm39) |
E42G |
unknown |
Het |
| Scn1a |
A |
T |
2: 66,155,182 (GRCm39) |
D592E |
probably damaging |
Het |
| Sdf4 |
T |
G |
4: 156,093,379 (GRCm39) |
V237G |
possibly damaging |
Het |
| Slc44a2 |
C |
A |
9: 21,258,068 (GRCm39) |
H439Q |
possibly damaging |
Het |
| Smg7 |
A |
T |
1: 152,720,123 (GRCm39) |
N761K |
possibly damaging |
Het |
| Snrpb2 |
A |
G |
2: 142,910,284 (GRCm39) |
E114G |
probably benign |
Het |
| Spmip11 |
A |
G |
15: 98,486,548 (GRCm39) |
H106R |
probably benign |
Het |
| Ssh1 |
T |
C |
5: 114,090,051 (GRCm39) |
D346G |
possibly damaging |
Het |
| Svopl |
T |
A |
6: 37,993,979 (GRCm39) |
I351F |
probably damaging |
Het |
| Tgfb2 |
A |
G |
1: 186,422,942 (GRCm39) |
S136P |
possibly damaging |
Het |
| Thsd7a |
A |
T |
6: 12,317,400 (GRCm39) |
L1636* |
probably null |
Het |
| Tmc2 |
A |
G |
2: 130,083,488 (GRCm39) |
T482A |
probably benign |
Het |
| Tnk2 |
C |
A |
16: 32,499,080 (GRCm39) |
P798T |
probably damaging |
Het |
| Trim5 |
T |
C |
7: 103,927,630 (GRCm39) |
Y170C |
probably damaging |
Het |
| Ttll10 |
T |
C |
4: 156,129,213 (GRCm39) |
M310V |
probably null |
Het |
| Unc13c |
T |
A |
9: 73,643,985 (GRCm39) |
T1160S |
probably damaging |
Het |
| Usp25 |
A |
T |
16: 76,904,819 (GRCm39) |
D795V |
probably damaging |
Het |
| Usp28 |
T |
A |
9: 48,949,148 (GRCm39) |
V914E |
probably damaging |
Het |
| Utrn |
A |
T |
10: 12,547,558 (GRCm39) |
C1627* |
probably null |
Het |
| Vmn1r28 |
C |
A |
6: 58,243,052 (GRCm39) |
F298L |
noncoding transcript |
Het |
| Vps29 |
T |
C |
5: 122,500,877 (GRCm39) |
S69P |
possibly damaging |
Het |
| Zfp703 |
T |
A |
8: 27,469,782 (GRCm39) |
L482H |
probably damaging |
Het |
|
| Other mutations in Kat6b |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00264:Kat6b
|
APN |
14 |
21,718,627 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01128:Kat6b
|
APN |
14 |
21,710,928 (GRCm39) |
missense |
probably benign |
|
|
IGL02272:Kat6b
|
APN |
14 |
21,676,846 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02349:Kat6b
|
APN |
14 |
21,687,661 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02402:Kat6b
|
APN |
14 |
21,681,415 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02474:Kat6b
|
APN |
14 |
21,719,107 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL02516:Kat6b
|
APN |
14 |
21,659,936 (GRCm39) |
splice site |
probably benign |
|
|
IGL02666:Kat6b
|
APN |
14 |
21,678,938 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02971:Kat6b
|
APN |
14 |
21,719,826 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03075:Kat6b
|
APN |
14 |
21,711,638 (GRCm39) |
nonsense |
probably null |
|
|
IGL03274:Kat6b
|
APN |
14 |
21,659,831 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL03308:Kat6b
|
APN |
14 |
21,674,902 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0118:Kat6b
|
UTSW |
14 |
21,720,042 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0383:Kat6b
|
UTSW |
14 |
21,719,149 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0441:Kat6b
|
UTSW |
14 |
21,720,301 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0457:Kat6b
|
UTSW |
14 |
21,720,598 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0558:Kat6b
|
UTSW |
14 |
21,719,489 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0662:Kat6b
|
UTSW |
14 |
21,712,417 (GRCm39) |
small deletion |
probably benign |
|
|
R0684:Kat6b
|
UTSW |
14 |
21,718,849 (GRCm39) |
missense |
probably benign |
|
|
R0755:Kat6b
|
UTSW |
14 |
21,687,661 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1216:Kat6b
|
UTSW |
14 |
21,672,108 (GRCm39) |
nonsense |
probably null |
|
|
R1479:Kat6b
|
UTSW |
14 |
21,669,024 (GRCm39) |
missense |
probably benign |
0.19 |
|
R1873:Kat6b
|
UTSW |
14 |
21,567,057 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1957:Kat6b
|
UTSW |
14 |
21,678,947 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2151:Kat6b
|
UTSW |
14 |
21,718,735 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2152:Kat6b
|
UTSW |
14 |
21,718,735 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2153:Kat6b
|
UTSW |
14 |
21,718,735 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2154:Kat6b
|
UTSW |
14 |
21,718,735 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2399:Kat6b
|
UTSW |
14 |
21,712,417 (GRCm39) |
small deletion |
probably benign |
|
|
R3740:Kat6b
|
UTSW |
14 |
21,720,112 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3771:Kat6b
|
UTSW |
14 |
21,567,166 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4178:Kat6b
|
UTSW |
14 |
21,668,972 (GRCm39) |
nonsense |
probably null |
|
|
R4261:Kat6b
|
UTSW |
14 |
21,719,737 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4551:Kat6b
|
UTSW |
14 |
21,711,516 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4724:Kat6b
|
UTSW |
14 |
21,711,030 (GRCm39) |
missense |
probably benign |
|
|
R5055:Kat6b
|
UTSW |
14 |
21,567,062 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5098:Kat6b
|
UTSW |
14 |
21,669,083 (GRCm39) |
splice site |
probably benign |
|
|
R5121:Kat6b
|
UTSW |
14 |
21,669,326 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5158:Kat6b
|
UTSW |
14 |
21,720,054 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R5488:Kat6b
|
UTSW |
14 |
21,719,332 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5489:Kat6b
|
UTSW |
14 |
21,719,332 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5653:Kat6b
|
UTSW |
14 |
21,719,440 (GRCm39) |
missense |
probably benign |
0.10 |
|
R5742:Kat6b
|
UTSW |
14 |
21,718,503 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5868:Kat6b
|
UTSW |
14 |
21,684,547 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5969:Kat6b
|
UTSW |
14 |
21,720,860 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6110:Kat6b
|
UTSW |
14 |
21,720,555 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6427:Kat6b
|
UTSW |
14 |
21,567,480 (GRCm39) |
missense |
probably benign |
0.24 |
|
R6457:Kat6b
|
UTSW |
14 |
21,720,748 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6639:Kat6b
|
UTSW |
14 |
21,567,562 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R6891:Kat6b
|
UTSW |
14 |
21,719,104 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7784:Kat6b
|
UTSW |
14 |
21,710,909 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7916:Kat6b
|
UTSW |
14 |
21,712,417 (GRCm39) |
small deletion |
probably benign |
|
|
R7977:Kat6b
|
UTSW |
14 |
21,719,931 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7987:Kat6b
|
UTSW |
14 |
21,719,931 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8266:Kat6b
|
UTSW |
14 |
21,566,913 (GRCm39) |
start gained |
probably benign |
|
|
R8483:Kat6b
|
UTSW |
14 |
21,719,461 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8902:Kat6b
|
UTSW |
14 |
21,719,629 (GRCm39) |
missense |
probably benign |
0.30 |
|
R8909:Kat6b
|
UTSW |
14 |
21,719,214 (GRCm39) |
missense |
probably benign |
|
|
R8931:Kat6b
|
UTSW |
14 |
21,674,995 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9112:Kat6b
|
UTSW |
14 |
21,675,256 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R9182:Kat6b
|
UTSW |
14 |
21,567,187 (GRCm39) |
missense |
probably benign |
0.20 |
|
R9224:Kat6b
|
UTSW |
14 |
21,720,031 (GRCm39) |
missense |
probably benign |
0.14 |
|
R9273:Kat6b
|
UTSW |
14 |
21,711,551 (GRCm39) |
missense |
probably benign |
0.07 |
|
R9332:Kat6b
|
UTSW |
14 |
21,720,093 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9380:Kat6b
|
UTSW |
14 |
21,678,926 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9397:Kat6b
|
UTSW |
14 |
21,675,244 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R9400:Kat6b
|
UTSW |
14 |
21,659,826 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9432:Kat6b
|
UTSW |
14 |
21,672,077 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9481:Kat6b
|
UTSW |
14 |
21,712,417 (GRCm39) |
small deletion |
probably benign |
|
|
R9526:Kat6b
|
UTSW |
14 |
21,567,564 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
| Predicted Primers |
PCR Primer
(F):5'- CATGGGAGGCAGTATCTGTG -3'
(R):5'- ACTGCTGCAGTTTGGCAAG -3'
Sequencing Primer
(F):5'- CAGTATCTGTGGAAACGGCTC -3'
(R):5'- CTGCAGTTTGGCAAGGCTGAAG -3'
|
| Posted On |
2020-07-13 |
Incidental Mutation