Incidental Mutation 'R8177:Slit3'
| ID |
634430 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Slit3
|
| Ensembl Gene |
ENSMUSG00000056427 |
| Gene Name |
slit guidance ligand 3 |
| Synonyms |
Slit1, b2b2362.1Clo |
| MMRRC Submission |
067602-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.897)
|
| Stock # |
R8177 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
11 |
| Chromosomal Location |
35012283-35599334 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 35469919 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Glycine
at position 307
(E307G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000066857
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000069837]
|
| AlphaFold |
Q9WVB4 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000069837
AA Change: E307G
PolyPhen 2
Score 0.987 (Sensitivity: 0.73; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000066857
Gene: ENSMUSG00000056427
AA Change: E307G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
23 |
N/A |
INTRINSIC |
|
LRRNT
|
33 |
65 |
2.12e-8 |
SMART |
|
LRR
|
59 |
83 |
1.37e2 |
SMART |
|
LRR_TYP
|
84 |
107 |
1.12e-3 |
SMART |
|
LRR_TYP
|
108 |
131 |
7.78e-3 |
SMART |
|
LRR_TYP
|
132 |
155 |
5.42e-2 |
SMART |
|
LRR
|
156 |
179 |
5.88e0 |
SMART |
|
LRR
|
180 |
203 |
7.55e-1 |
SMART |
|
LRRCT
|
215 |
264 |
1.33e-6 |
SMART |
|
LRRNT
|
279 |
311 |
6.79e-7 |
SMART |
|
LRR
|
305 |
329 |
1.16e2 |
SMART |
|
LRR
|
330 |
353 |
1.26e1 |
SMART |
|
LRR_TYP
|
354 |
377 |
2.79e-4 |
SMART |
|
LRR
|
378 |
401 |
4.05e-1 |
SMART |
|
LRR
|
402 |
425 |
4.05e-1 |
SMART |
|
LRRCT
|
437 |
486 |
7.75e-8 |
SMART |
|
LRRNT
|
504 |
536 |
1.95e-7 |
SMART |
|
LRR_TYP
|
556 |
579 |
7.49e-5 |
SMART |
|
LRR
|
581 |
603 |
6.41e1 |
SMART |
|
LRR_TYP
|
604 |
627 |
2.53e-2 |
SMART |
|
LRR
|
628 |
651 |
1.76e-1 |
SMART |
|
LRRCT
|
663 |
712 |
2.52e-7 |
SMART |
|
LRRNT
|
724 |
756 |
3e-8 |
SMART |
|
LRR
|
774 |
797 |
2.14e0 |
SMART |
|
LRR_TYP
|
798 |
821 |
2.95e-3 |
SMART |
|
LRR_TYP
|
822 |
845 |
2.43e-4 |
SMART |
|
LRRCT
|
857 |
906 |
1.12e-13 |
SMART |
|
EGF
|
919 |
953 |
6.86e-4 |
SMART |
|
EGF
|
958 |
994 |
8.84e-7 |
SMART |
|
EGF
|
999 |
1032 |
1.13e-4 |
SMART |
|
EGF
|
1037 |
1072 |
2.3e-5 |
SMART |
|
EGF_CA
|
1074 |
1110 |
5.92e-8 |
SMART |
|
EGF
|
1122 |
1155 |
3.79e-6 |
SMART |
|
LamG
|
1178 |
1314 |
3.16e-34 |
SMART |
|
EGF
|
1331 |
1365 |
2.19e-2 |
SMART |
|
EGF
|
1371 |
1403 |
1.13e-4 |
SMART |
|
EGF
|
1411 |
1444 |
5.57e-4 |
SMART |
|
CT
|
1455 |
1523 |
4.56e-5 |
SMART |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.9%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is secreted, likely interacting with roundabout homolog receptors to effect cell migration. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]
PHENOTYPE: Mice homozygous for a gene trap allele show congenital diaphragmatic hernia (CDH), variable renal defects and enlarged heart right ventricles. Mice homozygous for either of two reporter alleles show diaphragm dysgenesis and die prematurely; those with end-stage CDH show dyspnea and lung congestion. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 71 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 9830107B12Rik |
A |
T |
17: 48,439,174 (GRCm39) |
Y127* |
probably null |
Het |
| Abcb5 |
C |
T |
12: 118,836,525 (GRCm39) |
V1129I |
possibly damaging |
Het |
| Abcc2 |
A |
G |
19: 43,795,519 (GRCm39) |
D425G |
probably damaging |
Het |
| Adamts15 |
T |
A |
9: 30,833,322 (GRCm39) |
D71V |
probably damaging |
Het |
| Add1 |
A |
G |
5: 34,774,049 (GRCm39) |
H435R |
possibly damaging |
Het |
| Akr1c19 |
A |
G |
13: 4,292,591 (GRCm39) |
N204S |
probably benign |
Het |
| Ankub1 |
C |
A |
3: 57,597,837 (GRCm39) |
R44S |
possibly damaging |
Het |
| Ano3 |
T |
A |
2: 110,496,801 (GRCm39) |
N783Y |
probably damaging |
Het |
| Bbs9 |
A |
G |
9: 22,425,359 (GRCm39) |
M138V |
probably benign |
Het |
| Ccdc18 |
G |
A |
5: 108,345,661 (GRCm39) |
E936K |
possibly damaging |
Het |
| Cit |
T |
G |
5: 116,126,218 (GRCm39) |
L1604V |
probably benign |
Het |
| Col2a1 |
T |
A |
15: 97,874,654 (GRCm39) |
S1396C |
unknown |
Het |
| Col3a1 |
G |
C |
1: 45,374,924 (GRCm39) |
G653R |
unknown |
Het |
| Col6a1 |
T |
C |
10: 76,560,863 (GRCm39) |
E45G |
probably damaging |
Het |
| Col9a3 |
T |
A |
2: 180,249,450 (GRCm39) |
F271I |
probably damaging |
Het |
| Cyp2g1 |
C |
A |
7: 26,518,578 (GRCm39) |
D364E |
probably damaging |
Het |
| Dmbt1 |
T |
A |
7: 130,708,162 (GRCm39) |
V1457D |
possibly damaging |
Het |
| Dnah17 |
A |
T |
11: 118,019,753 (GRCm39) |
I98N |
possibly damaging |
Het |
| Dyrk1b |
T |
A |
7: 27,882,601 (GRCm39) |
M222K |
possibly damaging |
Het |
| Epha8 |
T |
C |
4: 136,672,974 (GRCm39) |
D270G |
probably benign |
Het |
| Fbxw17 |
T |
C |
13: 50,579,660 (GRCm39) |
L159P |
probably damaging |
Het |
| Fgl2 |
G |
A |
5: 21,578,307 (GRCm39) |
|
probably null |
Het |
| Fmnl1 |
A |
T |
11: 103,080,785 (GRCm39) |
M309L |
probably damaging |
Het |
| Fn1 |
T |
C |
1: 71,648,746 (GRCm39) |
I1479V |
probably benign |
Het |
| Gm11939 |
A |
T |
11: 99,450,124 (GRCm39) |
S57T |
possibly damaging |
Het |
| Gm9195 |
C |
T |
14: 72,697,977 (GRCm39) |
A1268T |
possibly damaging |
Het |
| Gnpda1 |
A |
G |
18: 38,466,348 (GRCm39) |
W90R |
possibly damaging |
Het |
| Igkv5-43 |
T |
A |
6: 69,800,445 (GRCm39) |
R81W |
probably damaging |
Het |
| Mapk3 |
T |
A |
7: 126,362,937 (GRCm39) |
W230R |
probably null |
Het |
| Mplkip |
A |
G |
13: 17,870,205 (GRCm39) |
S46G |
probably benign |
Het |
| Mrs2 |
T |
C |
13: 25,188,961 (GRCm39) |
T118A |
probably benign |
Het |
| Mst1r |
T |
A |
9: 107,784,784 (GRCm39) |
H147Q |
probably damaging |
Het |
| Muc5ac |
G |
C |
7: 141,361,068 (GRCm39) |
G1460R |
probably damaging |
Het |
| Myorg |
G |
T |
4: 41,497,568 (GRCm39) |
Y687* |
probably null |
Het |
| Naip1 |
T |
C |
13: 100,563,911 (GRCm39) |
H418R |
probably benign |
Het |
| Ncapg |
A |
G |
5: 45,851,095 (GRCm39) |
T763A |
probably benign |
Het |
| Nr6a1 |
T |
C |
2: 38,619,510 (GRCm39) |
I462V |
probably benign |
Het |
| Nudcd3 |
T |
C |
11: 6,143,460 (GRCm39) |
D70G |
possibly damaging |
Het |
| Nup210 |
A |
G |
6: 90,991,470 (GRCm39) |
S1858P |
probably benign |
Het |
| Or12e13 |
T |
A |
2: 87,663,512 (GRCm39) |
I43N |
probably benign |
Het |
| Or5aq1 |
C |
A |
2: 86,966,294 (GRCm39) |
V124L |
possibly damaging |
Het |
| Or6a2 |
G |
C |
7: 106,600,663 (GRCm39) |
L135V |
probably damaging |
Het |
| Or6c205 |
A |
G |
10: 129,086,790 (GRCm39) |
H129R |
probably benign |
Het |
| Or8k33 |
T |
A |
2: 86,383,623 (GRCm39) |
I282F |
noncoding transcript |
Het |
| Pde4dip |
T |
C |
3: 97,674,848 (GRCm39) |
T23A |
probably damaging |
Het |
| Pex6 |
A |
G |
17: 47,024,988 (GRCm39) |
Q347R |
probably benign |
Het |
| Rbm27 |
A |
G |
18: 42,457,175 (GRCm39) |
K694R |
probably damaging |
Het |
| Rnf40 |
T |
G |
7: 127,195,322 (GRCm39) |
D549E |
probably benign |
Het |
| Rpl22 |
A |
G |
4: 152,411,968 (GRCm39) |
K15E |
probably damaging |
Het |
| Rsph6a |
T |
A |
7: 18,808,164 (GRCm39) |
D697E |
unknown |
Het |
| Sec23b |
C |
T |
2: 144,427,543 (GRCm39) |
P590L |
probably benign |
Het |
| Semp2l1 |
T |
C |
1: 32,585,457 (GRCm39) |
E151G |
probably benign |
Het |
| Slc17a7 |
T |
A |
7: 44,824,356 (GRCm39) |
M524K |
probably benign |
Het |
| Slc28a1 |
G |
A |
7: 80,814,164 (GRCm39) |
D454N |
probably benign |
Het |
| Slc6a13 |
C |
T |
6: 121,301,987 (GRCm39) |
R190* |
probably null |
Het |
| Slc7a9 |
G |
A |
7: 35,155,558 (GRCm39) |
V257I |
probably benign |
Het |
| Slco1a6 |
T |
A |
6: 142,047,460 (GRCm39) |
M377L |
probably damaging |
Het |
| Smchd1 |
A |
G |
17: 71,697,448 (GRCm39) |
M1164T |
probably benign |
Het |
| Stk4 |
T |
C |
2: 163,930,777 (GRCm39) |
I126T |
probably damaging |
Het |
| Syndig1 |
A |
T |
2: 149,741,788 (GRCm39) |
S125C |
probably damaging |
Het |
| Synm |
T |
C |
7: 67,383,813 (GRCm39) |
D1283G |
probably benign |
Het |
| Tmprss6 |
T |
C |
15: 78,349,327 (GRCm39) |
M73V |
probably benign |
Het |
| Tmprss9 |
A |
G |
10: 80,730,882 (GRCm39) |
I803V |
probably benign |
Het |
| Tmx4 |
A |
T |
2: 134,485,822 (GRCm39) |
V35E |
probably damaging |
Het |
| Topbp1 |
T |
G |
9: 103,197,740 (GRCm39) |
S440A |
probably benign |
Het |
| Twf1 |
T |
C |
15: 94,482,276 (GRCm39) |
I157V |
possibly damaging |
Het |
| Vmn1r205 |
T |
C |
13: 22,776,415 (GRCm39) |
N229S |
probably benign |
Het |
| Vmn1r27 |
T |
A |
6: 58,192,759 (GRCm39) |
I82L |
probably benign |
Het |
| Vmn2r112 |
A |
G |
17: 22,822,594 (GRCm39) |
N424S |
possibly damaging |
Het |
| Vmn2r68 |
A |
T |
7: 84,871,422 (GRCm39) |
Y620* |
probably null |
Het |
| Zfp51 |
A |
G |
17: 21,684,129 (GRCm39) |
D248G |
probably benign |
Het |
|
| Other mutations in Slit3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00731:Slit3
|
APN |
11 |
35,512,981 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01324:Slit3
|
APN |
11 |
35,501,529 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01612:Slit3
|
APN |
11 |
35,591,211 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL02145:Slit3
|
APN |
11 |
35,520,569 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02146:Slit3
|
APN |
11 |
35,125,675 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
IGL02430:Slit3
|
APN |
11 |
35,068,601 (GRCm39) |
splice site |
probably null |
|
|
IGL02528:Slit3
|
APN |
11 |
35,469,801 (GRCm39) |
missense |
probably benign |
|
|
IGL02530:Slit3
|
APN |
11 |
35,598,969 (GRCm39) |
makesense |
probably null |
|
|
IGL02640:Slit3
|
APN |
11 |
35,591,172 (GRCm39) |
missense |
probably benign |
0.10 |
|
IGL02819:Slit3
|
APN |
11 |
35,062,417 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
IGL02839:Slit3
|
APN |
11 |
35,539,874 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
IGL03150:Slit3
|
APN |
11 |
35,399,084 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
IGL03161:Slit3
|
APN |
11 |
35,591,241 (GRCm39) |
missense |
probably benign |
0.10 |
|
IGL03336:Slit3
|
APN |
11 |
35,560,928 (GRCm39) |
missense |
probably damaging |
0.97 |
|
Bloated
|
UTSW |
11 |
35,524,779 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
Quellung
|
UTSW |
11 |
35,542,647 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02988:Slit3
|
UTSW |
11 |
35,598,890 (GRCm39) |
missense |
probably damaging |
0.99 |
|
PIT4791001:Slit3
|
UTSW |
11 |
35,552,072 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R0013:Slit3
|
UTSW |
11 |
35,598,745 (GRCm39) |
missense |
probably benign |
|
|
R0013:Slit3
|
UTSW |
11 |
35,598,745 (GRCm39) |
missense |
probably benign |
|
|
R0334:Slit3
|
UTSW |
11 |
35,469,928 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0385:Slit3
|
UTSW |
11 |
35,591,109 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0840:Slit3
|
UTSW |
11 |
35,514,263 (GRCm39) |
splice site |
probably benign |
|
|
R1065:Slit3
|
UTSW |
11 |
35,012,462 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R1364:Slit3
|
UTSW |
11 |
35,560,934 (GRCm39) |
missense |
probably benign |
|
|
R1476:Slit3
|
UTSW |
11 |
35,577,126 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1508:Slit3
|
UTSW |
11 |
35,461,448 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1665:Slit3
|
UTSW |
11 |
35,125,733 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R1692:Slit3
|
UTSW |
11 |
35,550,171 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1696:Slit3
|
UTSW |
11 |
35,566,750 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1727:Slit3
|
UTSW |
11 |
35,520,659 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1752:Slit3
|
UTSW |
11 |
35,455,480 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1970:Slit3
|
UTSW |
11 |
35,521,668 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R2077:Slit3
|
UTSW |
11 |
35,435,575 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R2126:Slit3
|
UTSW |
11 |
35,579,506 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2143:Slit3
|
UTSW |
11 |
35,503,088 (GRCm39) |
splice site |
probably null |
|
|
R2162:Slit3
|
UTSW |
11 |
35,579,509 (GRCm39) |
missense |
probably null |
1.00 |
|
R2873:Slit3
|
UTSW |
11 |
35,435,620 (GRCm39) |
nonsense |
probably null |
|
|
R3813:Slit3
|
UTSW |
11 |
35,566,806 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3831:Slit3
|
UTSW |
11 |
35,579,509 (GRCm39) |
missense |
probably null |
1.00 |
|
R3832:Slit3
|
UTSW |
11 |
35,579,509 (GRCm39) |
missense |
probably null |
1.00 |
|
R3833:Slit3
|
UTSW |
11 |
35,579,509 (GRCm39) |
missense |
probably null |
1.00 |
|
R3839:Slit3
|
UTSW |
11 |
35,399,064 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4152:Slit3
|
UTSW |
11 |
35,589,147 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4387:Slit3
|
UTSW |
11 |
35,574,875 (GRCm39) |
missense |
probably benign |
0.12 |
|
R4795:Slit3
|
UTSW |
11 |
35,542,647 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4910:Slit3
|
UTSW |
11 |
35,523,549 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4933:Slit3
|
UTSW |
11 |
35,579,420 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5048:Slit3
|
UTSW |
11 |
35,479,812 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5106:Slit3
|
UTSW |
11 |
35,503,194 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5138:Slit3
|
UTSW |
11 |
35,479,812 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5218:Slit3
|
UTSW |
11 |
35,575,002 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5338:Slit3
|
UTSW |
11 |
35,512,975 (GRCm39) |
missense |
probably benign |
|
|
R5354:Slit3
|
UTSW |
11 |
35,566,740 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5436:Slit3
|
UTSW |
11 |
35,598,738 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5896:Slit3
|
UTSW |
11 |
35,598,932 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5933:Slit3
|
UTSW |
11 |
35,520,578 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5963:Slit3
|
UTSW |
11 |
35,591,063 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5964:Slit3
|
UTSW |
11 |
35,591,063 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6125:Slit3
|
UTSW |
11 |
35,461,560 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6153:Slit3
|
UTSW |
11 |
35,591,310 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R6484:Slit3
|
UTSW |
11 |
35,552,125 (GRCm39) |
missense |
probably benign |
|
|
R6526:Slit3
|
UTSW |
11 |
35,552,119 (GRCm39) |
missense |
probably benign |
0.33 |
|
R6797:Slit3
|
UTSW |
11 |
35,524,779 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R6887:Slit3
|
UTSW |
11 |
35,435,633 (GRCm39) |
splice site |
probably null |
|
|
R7067:Slit3
|
UTSW |
11 |
35,399,057 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7150:Slit3
|
UTSW |
11 |
35,461,546 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7228:Slit3
|
UTSW |
11 |
35,490,245 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7232:Slit3
|
UTSW |
11 |
35,501,516 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R7418:Slit3
|
UTSW |
11 |
35,577,255 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R7545:Slit3
|
UTSW |
11 |
35,591,139 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R7727:Slit3
|
UTSW |
11 |
35,574,871 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7820:Slit3
|
UTSW |
11 |
35,591,235 (GRCm39) |
missense |
probably benign |
0.23 |
|
R8179:Slit3
|
UTSW |
11 |
35,554,903 (GRCm39) |
missense |
probably benign |
0.31 |
|
R8416:Slit3
|
UTSW |
11 |
35,399,062 (GRCm39) |
missense |
probably benign |
0.08 |
|
R8417:Slit3
|
UTSW |
11 |
35,501,438 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8476:Slit3
|
UTSW |
11 |
35,520,596 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R8785:Slit3
|
UTSW |
11 |
35,560,968 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8955:Slit3
|
UTSW |
11 |
35,589,207 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9040:Slit3
|
UTSW |
11 |
35,594,136 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9068:Slit3
|
UTSW |
11 |
35,574,917 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9088:Slit3
|
UTSW |
11 |
35,012,463 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R9266:Slit3
|
UTSW |
11 |
35,598,808 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9539:Slit3
|
UTSW |
11 |
35,589,155 (GRCm39) |
nonsense |
probably null |
|
|
R9636:Slit3
|
UTSW |
11 |
35,594,088 (GRCm39) |
missense |
probably damaging |
0.97 |
|
X0028:Slit3
|
UTSW |
11 |
35,455,464 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1176:Slit3
|
UTSW |
11 |
35,598,751 (GRCm39) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TCAAGCTGCATCTTGGGAAG -3'
(R):5'- CTACACTCTTGACAACTAGGCTG -3'
Sequencing Primer
(F):5'- CTGCATCTTGGGAAGCGAATC -3'
(R):5'- TCTTGACAACTAGGCTGAAGAAAAC -3'
|
| Posted On |
2020-07-13 |
Incidental Mutation